<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2015-11-11" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0K2WPD1</accession>
    <name>A0A0K2WPD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_467153_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001016">
        <property type="protein sequence ID" value="SCN47822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4675" checksum="FD35086975495A9E" modified="2015-11-11" version="1">MIQAAKRKARGYGKKHFKTMAYLLSGKLDLNRVNGFLPTCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL54</accession>
    <name>A0A1D3RL54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_372223_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000011">
        <property type="protein sequence ID" value="SCN46400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="106" mass="12081" checksum="C7AD7E60DB81468A" modified="2016-11-30" version="1">MWVIVGFVLATLVGRQKLSSIHRYICNRANWLYEITQTQKIKPISRAHLPRFLNGLDWSALNELIERCFGIKIDCTQSKKWIAIDGKALRGTLDAGDKQNIVLAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL67</accession>
    <name>A0A1D3RL67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_56150_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000024">
        <property type="protein sequence ID" value="SCN46421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015223">
        <property type="entry name" value="MipZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09140">
        <property type="entry name" value="MipZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="210" mass="23474" checksum="0B9A7CD451C7B733" modified="2016-11-30" version="1">MIILVGSQKGGCGKSTIATNIAAALATDGKDVMLVDADRQESSSNWALDRSENEDLKKVHSVQKYDDVRPTILDLKERYEYVIIDAAGRDSTELRTSMIVADALVMPVRPSQFDLDTVPRMQEIYNDAKILNSDLKFFSVITMGPTNPIINESRDAQDFFKNYSEITLLGTIIRERKVYRDAISGIGKGVVEMDNPKAKKEINDLLQEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLD7</accession>
    <name>A0A1D3RLD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holliday junction ATP-dependent DNA helicase RuvA</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ruvA</name>
        <name evidence="11" type="ORF">BAZMOX_04903_3</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Forms a complex with RuvB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RuvA family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000068">
        <property type="protein sequence ID" value="SCN46482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009379">
        <property type="term" value="C:Holliday junction helicase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14332">
        <property type="entry name" value="UBA_RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00031">
        <property type="entry name" value="DNA_helic_RuvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013849">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvA_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000085">
        <property type="entry name" value="RuvA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011114">
        <property type="entry name" value="RuvA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036267">
        <property type="entry name" value="RuvA_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07499">
        <property type="entry name" value="RuvA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01330">
        <property type="entry name" value="RuvA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46929">
        <property type="entry name" value="SSF46929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00084">
        <property type="entry name" value="ruvA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="HhH1" evidence="10">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="10">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="200" mass="21795" checksum="07B47BCFC2BE213E" modified="2016-11-30" version="1">MIGFLRGKLVAKVPPMLVLDVQGVGYEVEAPMTTFYNLPAMGEIVQLHTHLVVREDAHILFGFSTEADRVMFRTLIKVNGVGPKLALTILSGQSSDEFYRCIQDNDTATLIRLPGVGKKTAERLIVEMRDKLPTASDSPAEQTSVTDGAPRSHAKQEAISALCALGYKPADASKMVQNIAQEDKTCEEIIRLALQGKIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLI7</accession>
    <name>A0A1D3RLI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_12008_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000116">
        <property type="protein sequence ID" value="SCN46541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="1">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="367" mass="42574" checksum="3F8F3DAEBC6CFB61" modified="2016-11-30" version="1">MADTKKKPAKKKAVKKVIKKPPSLPVKSVQHDLFREFLSNDPEEVSNTVELWERIPKYFLSPEEQKNLRGSNGLAQPYVYSYVLRDKNGAPLPFKVKIQPALIEQPDGNHIAFFPTSAEEIIEEVLKKIFTEQNLGIHDVRNAESWVRFSYGMINKELRKNHCSKTHQQIKHSLEIMSKCIITAYEDDEEIYTGAILQDYCSVDRKKYLDDSKALHVARLPVFISHAVNTLQYRQFNYKRMMRLKSALSREILRRMINRFIQASLIKTYHFRFSTIQEETPYLRATKQSKNREKIIIALNELVKEGAIYGYELEKSKEGNKISDIKYVLNPTQEFCSEQKASNARANIIEDKAKLEGLGIVDKSKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK6</accession>
    <name>A0A1D3RLK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hydroxymethylpyrimidine phosphate synthase ThiC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_66939_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="FMJP01000122">
        <property type="protein sequence ID" value="SCN46546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="380" mass="42709" checksum="2B5DBB7DEF6E006B" modified="2016-11-30" version="1">MMWGIRWGGDTIMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLHHVPMTAKRMTGIVSRGGSIMAKWCLAHHTESFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQFAELETLGELTKIAWKHDIQTMIEGPGHVPLHMIEVNMTKQLEDCDEAPFYTLGPLTTDIAPGYDHITSVIGAANIGWYGCAMLCYVTQKEHLGLPNKEDVREGIVTYKIAAHAADLAKGHPGAQARDNAMSKARFEFRWEDQFNIALDPEKARSFHDETLPKDSAKIAHFCSMCGPHFCSMKISQDVREYAAEKGIKDAEEALQKGMDEKSQQFLEEGAEVYHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL8</accession>
    <name>A0A1D3RLL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RelB antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_265722_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelB/DinJ antitoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000132">
        <property type="protein sequence ID" value="SCN46560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015643">
        <property type="term" value="F:toxic substance binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044010">
        <property type="term" value="P:single-species biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026262">
        <property type="entry name" value="DinJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007337">
        <property type="entry name" value="RelB/DinJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38781">
        <property type="entry name" value="PTHR38781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04221">
        <property type="entry name" value="RelB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003108">
        <property type="entry name" value="DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02384">
        <property type="entry name" value="RelB_DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="83" mass="9368" checksum="E28C1D086B721C5B" modified="2016-11-30" version="1">MSATLKETTSIKLDKDSKEKAKLIFKELGITMGEAFNMFLSQVNLHHGLPFEMKIPNEVTKKVIKEARQGKNVDDFSLDELNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM4</accession>
    <name>A0A1D3RLM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_82098_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000133">
        <property type="protein sequence ID" value="SCN46563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="17371" checksum="83CB54E3D2BCD7E5" modified="2016-11-30" version="1">MDSLTDNGKGEFNHERDMSIGYPRMAEFCIAIGVPKSGLSTTYNDRNEPEEWRTWWMTEGVEDENGIPVRDEDEEMQATINLLKLAKSALGGLPVYLVIGNDLGLFASKVIKKLGKDGESDVIDGFIYVNRDTGEFVKYGRDSTIWKSSENTPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ7</accession>
    <name>A0A1D3RLQ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="7">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tilS</name>
        <name evidence="9" type="ORF">BAZMOX_07693_2</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000171">
        <property type="protein sequence ID" value="SCN46611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015262">
        <property type="entry name" value="tRNA_Ile_lys_synt_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09179">
        <property type="entry name" value="TilS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TilS_C" evidence="8">
        <location>
            <begin position="364"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="26"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="448" mass="50555" checksum="284BBDD6F25E835D" modified="2016-11-30" version="1">MKLNSSFIASQLLPFYAKSNIIVGYSGGVDSHVLLHLLTSLPEFKNKITAIYVHHGLQTCADAWAVHCQNCSKALGVKFKVLKVNGQAVPGESPEEAARNARYQAFKEILTSNDVLLFAQHRNDQLETVLLQLFRGAGLKGLSGMPVKASFVAGTLLRPLLDVSQEDIKQYALQHQLQWIEDPSNQDTQFDRNFLRQEILPLLEQRWPSLDKTVARVASHCAEAQMVLSANAKEQMLMLYDQQQRCLLITGLLQHDVLMQQWIVREWLGYLGVRMPSVKVLQAILQNILTARQEANPIVRHDGFDIQRYRDGLYLVAPQVPFDASQVFLWSDTSQPLPLNNNGRLLVSEAQQGIAVDLWQQGAVQIKYRQGGEKIALPNRTGRHSLKKLFQEAGIAPWLRARVPVIYMGDKIAAIADFWVSKDFYGTVGEPCIKLTWHKAHDEKFNID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS2</accession>
    <name>A0A1D3RLS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_83548_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000055">
        <property type="protein sequence ID" value="SCN46458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4738" checksum="521F32D72BA64052" modified="2016-11-30" version="1">MGFKAFHSAQATIAGIETAHMIRKEQLSEENIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS5</accession>
    <name>A0A1D3RLS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_39362_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000173">
        <property type="protein sequence ID" value="SCN46613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="91" mass="9897" checksum="DB7132B430E76AFC" modified="2016-11-30" version="1">MNWVQQNAKYLTIFALAMLMALTRSDHFGSAITLPDASLAVFYLAGIFTGGLASFAVLLTEAALLDYVAISQFQVSDYCISPAYILGSFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX0</accession>
    <name>A0A1D3RLX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_40961_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000201">
        <property type="protein sequence ID" value="SCN46662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="5055" checksum="7116F3BAC20E2F07" modified="2016-11-30" version="1">MKIIIDYDSSWRNSFLDPTTSNNEPLPKKGRKVCWLNDKSKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX8</accession>
    <name>A0A1D3RLX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome c oxidase (B(O/a)3-type) chain II</fullName>
            <ecNumber evidence="2">1.9.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11390_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.9.3.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000203">
        <property type="protein sequence ID" value="SCN46663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="63" mass="7079" checksum="F05BB63EEBED6D32" modified="2016-11-30" version="1">MHIDPLEKKWVQIALGMCTLFISIIMIDALFHGVNAPSNVETIDSRKIHLSEEFAEDNLGVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ9</accession>
    <name>A0A1D3RLZ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase J</fullName>
            <ecNumber evidence="1">2.1.1.242</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA m2G1516 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (guanine-N(2)-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmJ</name>
        <name evidence="2" type="ORF">BAZMOX_10024_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the guanosine in position 1516 of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(1516) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43220"/>
            <dbReference type="Rhea" id="RHEA-COMP:10412"/>
            <dbReference type="Rhea" id="RHEA-COMP:10413"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.242"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.242" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000213">
        <property type="protein sequence ID" value="SCN46683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008990">
        <property type="term" value="F:rRNA (guanine-N2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01523">
        <property type="entry name" value="16SrRNA_methyltr_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007536">
        <property type="entry name" value="16SrRNA_methylTrfase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36112">
        <property type="entry name" value="PTHR36112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04445">
        <property type="entry name" value="SAM_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="124"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="255" mass="28587" checksum="A218A01C1BA8F8CC" modified="2016-11-30" version="1">MPEYSGKLAVLHNEQYALNVSQALADRLAVPLYLNVDKNTAEDFFLSWRDGCLKLLDKELLKKGGLTVDIEPRNGEQRSWPAPKNSALAQAIGRKTKTVIDATTGWAQDSLHIFRMGYELRCIERSPIMLELLGDAYLRLEQLDWVQRLSLSVPELIAGNAIGVLSELTEAPECIYIDPMFPPKRKKSALPKKSMLILRDLLGDDMDKEQLFSTAMQATAKRVVVKSPDYAEPMGGTPSASFKGKLLRYDVYLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM55</accession>
    <name>A0A1D3RM55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">[NiFe] hydrogenase metallocenter assembly protein HypC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_34263_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HupF/HypC family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000248">
        <property type="protein sequence ID" value="SCN46733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019812">
        <property type="entry name" value="Hydgase_assmbl_chp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001109">
        <property type="entry name" value="Hydrogenase_HupF/HypC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35177">
        <property type="entry name" value="PTHR35177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01455">
        <property type="entry name" value="HupF_HypC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00445">
        <property type="entry name" value="HUPFHYPC"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00074">
        <property type="entry name" value="hypC_hupF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01097">
        <property type="entry name" value="HUPF_HYPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="78" mass="8290" checksum="6E57B323CDBE4E9C" modified="2016-11-30" version="1">MCLAVPGKVISISEADSLSRTGLVEFSGISTQVSLAYVPEAKVDDYVIIHAGFALSVLDQEEAEQSLLVFAQMDALSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM66</accession>
    <name>A0A1D3RM66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_415920_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000274">
        <property type="protein sequence ID" value="SCN46772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4289" checksum="AE1960A7636FC6B7" modified="2016-11-30" version="1">MKMLNQIFVGLAVLSVVILFGYLALWSWKDVKNHEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC2</accession>
    <name>A0A1D3RMC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_393598_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000297">
        <property type="protein sequence ID" value="SCN46804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="3"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="73" mass="8286" checksum="8D95F791AD13965F" modified="2016-11-30" version="1">MPEFNWINTVLGKLKTSLGGAYHAFDFAKYGTRYLGAFVYRFNRRFHLEALPLHLLVAAATTKPCPAGWLRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC7</accession>
    <name>A0A1D3RMC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein-export membrane protein SecD (TC 3.A.5.1.1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_47618_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000174">
        <property type="protein sequence ID" value="SCN46617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="217" mass="23345" checksum="A83EC674B6FCC69A" modified="2016-11-30" version="1">MRDAFSKRFQTTGLDSSQEARKLALLLRAGALAAPVDIVEERTVGPSLGQDNIDKGVLSVVVGFVLVLIFMAVYYKVFGLIADLALTFNLIVIIAVLSMLQATLTLPGIAGIVLTVGMAVDANVLIFERIKEELKNKQSPQTSIFLGYEKAFATIFDANITTLLVALVLFGFGTGPIKGFAITLAIGILTSMFTAILGSRMLVNWIYGGRRISKLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD3</accession>
    <name>A0A1D3RMD3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_127535_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000328">
        <property type="protein sequence ID" value="SCN46851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="153" mass="17126" checksum="D6F2A41E852A748D" modified="2016-11-30" version="1">MDLACGLGANALLLAQQGMTVQAWDISTLALQKLQVQADTEALSIKTFTKEITPYSFSINSFDVVVVGRFLDRSICNAIMECLKPNGLLFYQTYTQHKVYLHGPKNPKFLLADNELLSLFSPMKVIYYRENSAVGDTRQGLRNEAQFIGQKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF0</accession>
    <name>A0A1D3RMF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00523_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="164" mass="18516" checksum="700241C2F5BE67EB" modified="2016-11-30" version="1">MDLIDLNTKNCLEKLVDSVTSEVGRALIGLTVMQLTIKSIDSTQNIRLHKGGTGSNSFSWKDGISMRVLDKNYVTPVLRKYDLVKLNADGFMMTRSLAENYPYSSLYKAQLKGARIEWLSVVESLEGNLSDPFNSLKYFVSLLFNKAEQFQLVSDNLLKKQILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMG2</accession>
    <name>A0A1D3RMG2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Integration host factor subunit alpha</fullName>
            <shortName evidence="8">IHF-alpha</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ihfA</name>
        <name evidence="8" type="synonym">himA</name>
        <name evidence="11" type="ORF">BAZMOX_122560_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8 10">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000223">
        <property type="protein sequence ID" value="SCN46698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13835">
        <property type="entry name" value="IHF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00380">
        <property type="entry name" value="IHF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005684">
        <property type="entry name" value="IHF_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00987">
        <property type="entry name" value="himA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 8 10" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="98" mass="11136" checksum="AA2A71ACA77A9D06" modified="2016-11-30" version="1">MAVIKADFAERLFDELGLNKREAKEMVELFFEEIKLALETGEQVKISGFGKFELRDKSSRPGRNPKTGEEIPISARRVVTFRTGQKLKTRVEAYAGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI9</accession>
    <name>A0A1D3RMI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_70760_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000350">
        <property type="protein sequence ID" value="SCN46890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="5">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="131" mass="14069" checksum="11A74E302EC21CAA" modified="2016-11-30" version="1">MALLEPVSQPLVIPEKQGPYVILVVGVNGAGKTTTIGKLAQRLQQQGRSVMLAAGDTFRAAAVEQLQVWGERNEIHVVAQHTGADSASVIFDAVQSAQAKGVDVLIADTAGRLHTKSNLMEELKKTKTYYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ9</accession>
    <name>A0A1D3RMJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_55192_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000216">
        <property type="protein sequence ID" value="SCN46687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="49" mass="5559" checksum="767E3ECC6BDD942B" modified="2016-11-30" version="1">MIDTINLPTLLTLLRIALIPVLAIFFYVPWEYSNIATTLIFLLPVLQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK1</accession>
    <name>A0A1D3RMK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase</fullName>
            <ecNumber evidence="4">1.8.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_11318_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.8.1.8" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000355">
        <property type="protein sequence ID" value="SCN46900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase (NAD(P)) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1250">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028250">
        <property type="entry name" value="DsbDN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036929">
        <property type="entry name" value="DsbDN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022910">
        <property type="entry name" value="Thiol_diS_interchange_DbsD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32234:SF0">
        <property type="entry name" value="PTHR32234:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11412">
        <property type="entry name" value="DsbC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74863">
        <property type="entry name" value="SSF74863"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920230" evidence="2">
        <location>
            <begin position="22"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC" evidence="3">
        <location>
            <begin position="25"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC" evidence="3">
        <location>
            <begin position="176"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="435" mass="48675" checksum="09282D3A0BFB8F46" modified="2016-11-30" version="1">MHHVKIVLSCFFILFSQVTFAIDPDDLLTPEQAFKVSAQATEDGNLLISWDIAEGYYLYRNKMLFTSKTEAITVKHADLPAGKVKSDKYFGDVVIYRHHLESKLTLQRPEKAVSFSLLVKHQGCADLGICYPPQKTLLTIQLPAINTPVSTESSANPLQQLSKSFNLGLNLFKNEAELLPAEEAFQFSAFVKEGKNLRVNWQIAKGYYLYREKIDLELLDSNNTKLLDYEIPHGTPKFDEAFGDVEILHNNVAFTIPLERLHATQHSITLRAKFQGCAERGVCYPPMDKTVTLLLPEIAATELSTPASQIKKNTRSEQDLIVQSLQQDSFFLTLLSFLGFGLLLAFTPCVFPMIPILSGIIVGQGKDISSRKAFLLSLSFVLASAMTYTVFGILAALFGSNLQATFQAPWIIYLFSGSFYPTVTVNVWFLSFRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK2</accession>
    <name>A0A1D3RMK2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="10" type="ORF">BAZMOX_19473_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000373">
        <property type="protein sequence ID" value="SCN46925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="267" mass="29558" checksum="7EB4B070CFB40BD9" modified="2016-11-30" version="1">MVAASKMRKTKDRMQATRPYSKKISQIIRHLAHANPEYKHPFLIDREVKRIGVIVITSDRGLCGGLNSNLFRTVLKDLVAWEKDSIEVDICTIGTKGSSFFAGINANLVAQIGKLGDTPHLDDIVGIIKVMLDSYSNGTIDELYVVSNEFVNTMTQKPIVEKLIPVVAAELEDDAEDHFGNKHWDYLYEPDAKDVLDTLLTRYIESIVYQGVVENNACEQSARMVAMKSASNNAANIIDELQLVYNKARQAAITQETSEIVAGAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK3</accession>
    <name>A0A1D3RMK3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein BAZMOX_11843_0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_11843_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000353">
        <property type="protein sequence ID" value="SCN46893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="91" mass="9873" checksum="E647311FC8C29A10" modified="2016-11-30" version="1">MKGALGNIMQQAQQMQEDMQKAQAELENLEVTGESGGGMVSILMTGKREVRKVSIDDALVGDDKEMLEDLVAAAINDAVRKVAKLKKRKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK8</accession>
    <name>A0A1D3RMK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_122560_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000223">
        <property type="protein sequence ID" value="SCN46697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="117" mass="13639" checksum="96CBA743BF6D16CE" modified="2016-11-30" version="1">MLEPSNNNELPAIPAKRYFAIGEVSELCGVKPHVLRYWEQEFEQLEPVKRRGNRRYYQRNDVMLIRQIRALLYEQGYTIGGARAHLLSDDAKGDSVRTKQVIHQMIGELEDILEILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ1</accession>
    <name>A0A1D3RMQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTP pyrophosphokinase, (P)ppGpp synthetase II / Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase</fullName>
            <ecNumber evidence="5">2.7.6.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_00824_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000397">
        <property type="protein sequence ID" value="SCN46952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="62"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="403"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="651"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="725" mass="82361" checksum="83F515B62389AD35" modified="2016-11-30" version="1">MNAQATTSIPSTPDSPEHILFTQLSALLSEYLEPPQLKQVQQAYQFGEQHHLGQFRKSGEAYICHPLAVAISLAKMRMDVHGIMAAILHDVIEDTDASKQDIIELFGDDVAELVDGVTKLTQLNSITKAEAQAENVRKMCLAMTKDLRVIMVKLADRLHNMKTLGVMRPDKKFRIAKETLDIYTPIANRLGMNKIRHQLESLCFEAMYPMRHRILKEAIKKARGHRKEIIETINNSIRNRLEQAEVVCEVHGREKHLYSIYNKMHLKKLSFSDIFDVYAFRIHCEYVDTCYRILGIVHNLFNPIPGKFKDYIALPKANGYQSLHTVLIGPYGVPIEIQIRTHQMHRMSESGIAAHWLYKSENGENTNSKTRAAEWVHDLLEIQKTAGNSLDFIESLKIDLFPQEIFVFTPQGNIIKLPRKASIVDFAYAVHTDIGNSCVSARINKRLVPLQSQLDNGVTVEVITASWARPNPLWLNYVITTKARTGIRSYLKHFKQQEAINLGRRLLEKELSDLGKHVDDITEEMQAQLLTALKYTTMDNLLSDIGLGNKMPFLVAKQLNQEDIHAQIKLNDNETRKESPLIIKGTEGMIVTLAKCCRPIPGDPIIGYFNPGKGIVVHNHECHNTPDGRKRQTDWLEVEWCPEASGDYPAEIRIELENRRGTLATIASTISQMDSNIENVYIADQDARVSVDLVTLTVKDRKHLANIMRQLKKLPIVLKITRTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ9</accession>
    <name>A0A1D3RMQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helix-turn-helix protein, CopG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_48536_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000425">
        <property type="protein sequence ID" value="SCN46985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5360" checksum="BEDD0BBCF9415D54" modified="2016-11-30" version="1">MIQAIKEHLDNLEDLYLAEQRLIENRAGRSKTYTLDEVERDLGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR4</accession>
    <name>A0A1D3RMR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_84672_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000326">
        <property type="protein sequence ID" value="SCN46849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4242" checksum="6ABD30E306E32B08" modified="2016-11-30" version="1">MNSDALEFLLFLTYNISSVMFEKGAHLKFGGYLKENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS3</accession>
    <name>A0A1D3RMS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_265192_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000415">
        <property type="protein sequence ID" value="SCN46972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="81" mass="9213" checksum="0A6910EE218319DD" modified="2016-11-30" version="1">MAGAIRFHWGVESNNWIRDVTFNEDHIKTKAGNQAQIMALLRGLAIELIRKTSPKNFQAAIENLSDSVDNLESMLRQVKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV5</accession>
    <name>A0A1D3RMV5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ORF">BAZMOX_00289_5</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="FMJP01000434">
        <property type="protein sequence ID" value="SCN47002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="105"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="316"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="107"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="454" mass="48110" checksum="F287F6DE2E0C6104" modified="2016-11-30" version="1">MILMTLQEIAEAVQGKLVGTDATVSGVCIDTRILAEGDLYIAIKGEQFDGHDFIAQAEKKGTLALLVAKQVTSDKPQIIVKDTRLALAQLAGAVRAKVQVKVCGITGSNGKTTVKEMVAAVLAVNYRVLFTQGNFNNATGVPLTLLRLQAEDEFAVIEMGANHAGEIAYMSAYAQPDVVVITNVGAAHIEGFGSIEGIALAKAEIIESLTDQGIAVLNADDTFFAQWLALAGQRKVLSFGLNANADVTAENIVTGFAGEQFCTQFDLLSEGKRVPIRLALAGEHNVKNALAASSACLALGIEVKQIQEGLKQVKVVKGRLQLSVTGLGYRVINDTYNANPDSLTAALAVLKNCEGELWFALGAFGELGAGAEQLHSEMGQKIKQAGVTRLFVTGALAKSTVKAFGVGAEFFTQQEDLITAVQQAINPKVVLLVKGSRVQRMENVVNALVNKVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW2</accession>
    <name>A0A1D3RMW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3">2.3.3.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_04316_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000451">
        <property type="protein sequence ID" value="SCN47031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="256" mass="27745" checksum="103C192CFAC38D25" modified="2016-11-30" version="1">MELVMKDKLIIFDTTLRDGEQSPGASMTRDEKVRIARALERLKVDIIEAGFPAASEGDFAAVQAVAETVKNSTVCGLSRALDRDIDRAGEALKGAERSRIHTFIATSPIHMQMKLKMEPEQVIEYAVRAVKRARQYTDDVEFSAEDAGRSDEDFLCRILEAVIDAGASTLNIPDTVGYSIPSEFGATIASLMQRIPNADKAIFSVHCHNDLGMAVANSLSAVMNGARQVECTINGLGERAGNASLEEVVMAIKNTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY7</accession>
    <name>A0A1D3RMY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_161123_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000369">
        <property type="protein sequence ID" value="SCN46919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="3944" checksum="98DBB4098ADBAC3F" modified="2016-11-30" version="1">MGIPAQVSGKNLTRLLIAFGAPIRPRHFVPTQQAVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ7</accession>
    <name>A0A1D3RMZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="16">FIG004556: membrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BAZMOX_03068_1</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000379">
        <property type="protein sequence ID" value="SCN46929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06158">
        <property type="entry name" value="S2P-M50_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044537">
        <property type="entry name" value="S2P-M50-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 16" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="15">
        <location>
            <begin position="138"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SCN46929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="215" mass="23683" checksum="3603FD9DA74CAB43" modified="2016-11-30" version="1">MDELTLVQKIVVWVIPVIFAITVHEVAHGWVAKQYGDKTAWMLGRLTLNPLKHIDPVGTILVPGLMLAFTGFVFGWAKPVPVNIRNLRNPKHDMAIVALAGPAANFLMALGWALFARLGILINTPEFSIPMIYVGIAGIMINLILGLLNLLPIPPLDGSRILSWILPGRLSLYYDQFEKYGFYLLVLLLMTDSLGVVLGYPLSIAKGFFFSIAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ9</accession>
    <name>A0A1D3RMZ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_12464_4</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000493">
        <property type="protein sequence ID" value="SCN47085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="88"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="321" mass="36096" checksum="9510CF6F822EE910" modified="2016-11-30" version="1">MEYAAFAENHHFQIPAGAHWNDVRETTVNIGAALQGAMRAIEKANPDTLFGIFGDASWTNKDRLSDEILTNLVEHYSQHKLNISTVPDDKLGDAYKYLIKEFADDSGHTAAEFYTNRTVVKLMTMIMDPQPGESVYDPTCGSGGLLLNCALHLKDEGKEYRTLKLYGQEINLLTSAIARMNMFLHGIEEFSIIRGDTLANPSLLDNDQLKTFNVILANPPYSIKAWDRKAFESDPYGRNLWGTPPQGCADYAFQQHIQKSLDNKNGRSISLWPHGILFRDAENSMRRKMIEQDLVECVIGLGPNLFYNSPMEACLLITKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN03</accession>
    <name>A0A1D3RN03_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimM</name>
        <name evidence="5" type="ORF">BAZMOX_00434_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="3">
        <location>
            <begin position="8"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="4">
        <location>
            <begin position="96"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="167" mass="18772" checksum="CE4B68FD025E816D" modified="2016-11-30" version="1">MAEEFISVGLVSGIFGVRGWIKVYSYTDPRENILNYSPWTLRKGKDSKKVKVIDGRRHGKTVLACLEDINDRDEAANLSGWEILICPEQLPKAKKGEYYWSDLIGLQVNTVDGVELGVVKQMLETGANDVVVVMGERERLIPFLQEQTILSIDLPAGVMIVDWDAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN15</accession>
    <name>A0A1D3RN15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">23S rRNA (Guanosine-2'-O-)-methyltransferase rlmB</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_01117_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000457">
        <property type="protein sequence ID" value="SCN47036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01887">
        <property type="entry name" value="23SrRNA_methyltr_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024915">
        <property type="entry name" value="23S_rRNA_MeTrfase_RlmB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="4">
        <location>
            <begin position="5"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="247" mass="26902" checksum="DC101E66CBBDEEC4" modified="2016-11-30" version="1">MSLAKIFGVHAAQSALDYSPEKINQAWVDQKRQDERLQGLVKGLGQRGINIQKADRKQLDSLSKGANHQGIILEVEMPAMHSENDLKSVVESAKQVPFWLILDHVQDPHNLGACLRTADAAGVQGVIVTKDQAVGITPTVCKVACGAAETVLVYQVTNISRTIAWLKEQGVWVVGAAGEAEKTIYETDVNMPIALVMGAEEKGMRRLTREQCDFLVKIPMQGSVESLNVSVAAGVLIYEVFRQRLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN39</accession>
    <name>A0A1D3RN39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_20759_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000529">
        <property type="protein sequence ID" value="SCN47125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="86" mass="10035" checksum="07EB3CD7E01346D0" modified="2016-11-30" version="1">MARKDRVDRSHFGVTRVEEKRNITTGRSTPIRFTAEEIDQLDLLVEKIQKKIPQKKISKSKVLRASVYLQDDKRIAELIKSIKENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN89</accession>
    <name>A0A1D3RN89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_249438_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000543">
        <property type="protein sequence ID" value="SCN47142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="61" mass="6520" checksum="8858CEC03ED09D4F" modified="2016-11-30" version="1">MIARLSGISNSVPFEAAVDSLAIAENNSSVNNSVFICKVPAQGLLKVKSYWPLGRTILLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN91</accession>
    <name>A0A1D3RN91_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="7">DHBP synthase</shortName>
            <ecNumber evidence="7">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribB</name>
        <name evidence="9" type="ORF">BAZMOX_02217_3</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000520">
        <property type="protein sequence ID" value="SCN47114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="8">
        <location>
            <begin position="206"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="7">
        <location>
            <begin position="25"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="7">
        <location>
            <begin position="138"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="7">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="7">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="367" mass="40321" checksum="99699A8507A98177" modified="2016-11-30" version="1">MNTTEEIIEDIRQGKMVVIMDDEDRENEGDLIMAAELVRAADINFMARYGRGLICLTLTGERCQQLRLPLMVNDNNAAFATNFTVSIEAAEGVTTGISAADRAKTILSAVATDAKAEDVVQPGHIFPLRARDGGVLNRAGHTEAGCDLARLAGLEPASVIVEVLNEDGSMARRPDLEVFAKEHELKIGTIADLIQYRTKNEATLERISECALPTEFGDFRLYAYQDRNDGNIHLAIVMGDVANDEPVLVRVHARNLMDDIFSSTRSDCKMPVRDAMKHIAKEGRGVLVLIRQEENNKALAELVHQYQLQDNGVINPVVAEKTGEWRTTGTGSQILADLGVHKITVLGEQKTYFGLSGFNLELVESSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN96</accession>
    <name>A0A1D3RN96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thiol peroxidase, Bcp-type</fullName>
            <ecNumber evidence="5">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_23113_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.11.1.15" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000423">
        <property type="protein sequence ID" value="SCN46978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="157" mass="17788" checksum="29E9C9FE90D548CD" modified="2016-11-30" version="1">MSSVTLGSPVPNFEAISTGDKSIQLSDYRGKYLILYFYPRDNTPGCTTEGQNFRDKIAEFSALNAVILGVSRDSVRVHEGFKAKQNFPFDLLSDQEEKLCTLFDVIKMKNMYGKKVQGIERSTFLIDPNGILIHEWRKVKVKVHIDEVLQTLKELGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC3</accession>
    <name>A0A1D3RNC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS2020, hypothetical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_441818_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000474">
        <property type="protein sequence ID" value="SCN47049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="71" mass="8102" checksum="C8F2F7A1274AE86E" modified="2016-11-30" version="1">MIDICQVKYLNNIIEQDPRFIKKITKPMMEFKAFHSAQATIAGIEAAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE5</accession>
    <name>A0A1D3RNE5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_10545_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000565">
        <property type="protein sequence ID" value="SCN47166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="7">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="101" mass="11464" checksum="1EA15F9CCADE558B" modified="2016-11-30" version="1">MDRGRLTARQIEAARRTITRHCKRDGKLWIRVFPDKPITNKPLATRMGKGKGGVEYWIAQIKPGTMLYELQGVPETLAREAFALAAAKLPIKTKFIIRTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG0</accession>
    <name>A0A1D3RNG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_472727_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000589">
        <property type="protein sequence ID" value="SCN47220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="7005" checksum="A88C557803FA6DAC" modified="2016-11-30" version="1">MNNIIEQDHRFIKKITKPMMGFKAFHSAQTTVAGIEAAHMIRKGQLSEEKIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH0</accession>
    <name>A0A1D3RNH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_112116_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000469">
        <property type="protein sequence ID" value="SCN47048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4728" checksum="60396836EFF626F5" modified="2016-11-30" version="1">MPAYKQFMALAGWLCLKTRRTSLSLVLATEPDIRPRYANED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ6</accession>
    <name>A0A1D3RNJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase, IS30 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_44336_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000586">
        <property type="protein sequence ID" value="SCN47216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="55" mass="6487" checksum="9DF4D023EB7F93D8" modified="2016-11-30" version="1">MYKPRVVEALDCDTYFAKPYSSWERGQNENANGLLRQYFPKAMELIFEELLAKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK7</accession>
    <name>A0A1D3RNK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02905_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000594">
        <property type="protein sequence ID" value="SCN47226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4927" checksum="6748A521560B8244" modified="2016-11-30" version="1">MENSNIFRAIAIVLHVVFRLEQVTLNFAQSPIGVITRSITSKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL3</accession>
    <name>A0A1D3RNL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exonuclease SbcC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_218693_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000630">
        <property type="protein sequence ID" value="SCN47270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="82" mass="8762" checksum="EE46479CD2FA3825" modified="2016-11-30" version="1">MGLSDVVQERSGGIQLDTLFIDEGFGSLDQDSLQLAINTLIDLQSAGRAIGIISHVSELKEQMAQRIEVTGSRSGSTIKMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN7</accession>
    <name>A0A1D3RNN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_85627_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000633">
        <property type="protein sequence ID" value="SCN47283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="63" mass="7425" checksum="F4C76B445AFF5572" modified="2016-11-30" version="1">MKQMDLIDWLDGKRVIRQQPPTIATQHRLFIIEQLKPIMRELEALELSALTISEAMAHYQNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ7</accession>
    <name>A0A1D3RNQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_398836_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000649">
        <property type="protein sequence ID" value="SCN47303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="10227" checksum="E597C4B461201E0B" modified="2016-11-30" version="1">MSKDPVHLLVSAPPNLAPSEIMRRIKGRRASKVFESFPDLKKRYWGRHFWARGYFCVTSGELTEEMIKNYLEHHFEPKGDDNFKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR2</accession>
    <name>A0A1D3RNR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FIG005080: Possible exported protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01495_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000666">
        <property type="protein sequence ID" value="SCN47321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011836">
        <property type="entry name" value="CHP02099"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38690">
        <property type="entry name" value="PTHR38690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsmA_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="274" mass="30104" checksum="E4635B62449960DD" modified="2016-11-30" version="1">MIHDFPALNIQSKALYWQGVNLGQLELLTQPAPNGLLIKKLVLNTDQEQLSLVGNWQQQGATNKTTIKGTLHSKNFGQLLHQIHISDNLVNTTANIQFTLNWADAPYAFSSTNLSGDLNLQMTNGRILGVNPGLGRILGALDIWKINKRLHLDFSDVTEEGLSFSEINADITIDQGLLSSNNFYINAMPAKIDLSGTTHLDTKQININATVLPKFPIAGTIIGSIANSVTKTFTGDEHAGGFLLSLLYKITGTWENFVIVRQFDRVTPEPLKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR7</accession>
    <name>A0A1D3RNR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_01797_3</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000517">
        <property type="protein sequence ID" value="SCN47107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="6">
        <location>
            <begin position="35"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="5">
        <location>
            <begin position="200"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="690" mass="76368" checksum="259D7BB89EEF27C9" modified="2016-11-30" version="1">MALPLVGHAETEQLTTIVVEGSGSRPGTFALAPDSSGFKDTAALLERVPGANVNRNGPLTGIPQYRGMFGNRVNVEIDGANIKEAGPNSMDTALSHIPAVLTESLTVYRGIAPVSSGIDTIGGTMKVKTKKGHFAETEDDIVSEGAVSSGFSSVDKGYFVSGFTSLANENHKLHVGVSKEEGNDYRYKEREGKKVIPTEYDRRGLIAGYSYQRNGHELSFNYTDNDTRNTGSPALPMDIVYIKSHIYNLDYNWDLGQGYELKTKFFYQNSDHLMDNNTLRVPKPNGSDRLMDNTTNVQGGGWDIALSMPLLSGDFTTGFTGDTSRHNSNIHMNAAMAPGAMPMDIYTQNFNDVERSRYSFFGEWKGEVANKLNAELGARLTYTNSDAGDVSTTMMPLKPFANDFNSKGHNKDFVDVDLTAILRYVMRDDLDFELGFARKNRAPSYQELYLWSPAEATSGLADGRSYLGNLELDMEHAYQFEFGMDWHTDEAYLAPRAFVHYVNDYIQGTPSSVMRTQTSCPTSNSCPVLQFENIEALLYGIDLELGYIFTDWVRFDAGLNYVGGNRLDGPEGNLYRIAPLNGRMQLTFNYSGFTTSIEGILYAEQKNVASYNNEQSTPGYEIMNLRASYEAFDGFTFGTGIENVLDSTNLNHLGGYYRPNAATDAGNGVTTGDRIPMQGRNYYATVSYQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT2</accession>
    <name>A0A1D3RNT2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ORF">BAZMOX_10702_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000679">
        <property type="protein sequence ID" value="SCN47340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="43"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="152"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="355" mass="38633" checksum="AE73342A6D1C5F7D" modified="2016-11-30" version="1">MSASETLDYSSNIFKIKPMYILGIETSCDETGVAIYHSEKGLIHHCLYSQIAMHNLYGGIVPELASRDHIRKLIPLIHECLKSSQLTKTDIGGIAYTAGPGLIGALLVGAATAKSLAWTWGIPAIAVHHMEGHLLAPMLEDNPPAFPFVALLISGGHTLLVKVTDIGQYELLGESLDDAAGEAFDKAAKMLGLSYPGGPLLAKMAEQGNPERFKFPRPMTDRPGLDFSFSGLKTFTLNTLNSTKQTDQDKADVALAFQKATAETLAIKCKRALKQTGLKRLVVAGGVSANTYIRQTLTDMTQKERAEIFFPRPEFCTDNGAMIAYAGSRHLKTQQSESLAIQAKPRWPINELYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU8</accession>
    <name>A0A1D3RNU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ion-translocating oxidoreductase complex subunit E</fullName>
            <ecNumber evidence="7">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Rnf electron transport complex subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rnfE</name>
        <name evidence="8" type="ORF">BAZMOX_36003_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000660">
        <property type="protein sequence ID" value="SCN47316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00478">
        <property type="entry name" value="RsxE_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010968">
        <property type="entry name" value="RnfE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01948">
        <property type="entry name" value="rnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="222" mass="23973" checksum="244AD2F1593DD2A0" modified="2016-11-30" version="1">MTQATKKETPLTLDVFTAGIWKENPVFVMMLGLCPVLAVTNSVLNSLAMGIASIFVLVCSNALVSALRNFIPKQVRITTYIIIIATFVTLVDYIIQAVSLDLYNKLGAFIQLIVVNCLILGRAEAYASKNSFTKSVVSALGMGLGFTLALVMLGGVRELLGAGQLLGYQVFSTQFEPWVVMILPPGGFIVLGSWLLLINYIQQRKTGQIIAADATAHCTVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW5</accession>
    <name>A0A1D3RNW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_45768_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000732">
        <property type="protein sequence ID" value="SCN47415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="82" mass="9676" checksum="6732F57654707D1A" modified="2016-11-30" version="1">MISFKCAQFPKDVILYAVFYYVRYGVSYRDLEEIVVEREGLMLIMLRSIVGLSVMRQPLLQKLTLRNETQIDLGAWMKRISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP07</accession>
    <name>A0A1D3RP07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoserine aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphohydroxythreonine aminotransferase</fullName>
            <shortName evidence="6">PSAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">serC</name>
        <name evidence="9" type="ORF">BAZMOX_02254_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 6 7">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="6">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6 7">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 6">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000572">
        <property type="protein sequence ID" value="SCN47187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00611">
        <property type="entry name" value="PSAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PTHR43247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01364">
        <property type="entry name" value="serC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="6 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="5"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="359" mass="39316" checksum="CB19BDA322B29B70" modified="2016-11-30" version="1">MSKTYNFSAGPSMLPESVLQQAQAEMLDWQGSGMSVMEMSHRGPEFMGIAEVLHRDLRELMAIPDNYKILFLQGGATAQFSFIPTNVLGDKNKACYVNTGAWSGKALKAAKNYCDVVVSASAETNNFTAIPDPSTWNIDQQAAYLHYTSNETIHGLEFANIPNVGSLPLVADMSSNILSRQIDVSKFGLIYAGSQKNMGPAGVTVVIVREDLLGKAQSTLPNVFNYQQQVKYESMLNTPVTYSWYLVGLVLQWLKAQGGIAGIEQVNQRKAQNLYAAIDCSSLYSNAVAIADRSRMNVPFILADKGLESVFLKAAQEQGFLALKGHRLLGGMRASIYNAMPESGVEALVQFMAEFERTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP09</accession>
    <name>A0A1D3RP09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_26386_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000736">
        <property type="protein sequence ID" value="SCN47421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4142" checksum="127437D62E3C3F78" modified="2016-11-30" version="1">MFKEPGSKMLLFTFNNITRQSITINGVLNSNAARDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP13</accession>
    <name>A0A1D3RP13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplU</name>
        <name evidence="6" type="ORF">BAZMOX_04234_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000632">
        <property type="protein sequence ID" value="SCN47279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="103" mass="11712" checksum="30D348B60A2E8831" modified="2016-11-30" version="1">MYAVIQTGGKQYRVEEGTTLKIEKLELGMGDSVEFDNVLMVQSDNAVKIGQPYVDGSKVTATVVSQGRHKKVKIIKFRRRKHHMKQMGHRQYYTEIQITGISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP61</accession>
    <name>A0A1D3RP61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_45768_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000732">
        <property type="protein sequence ID" value="SCN47412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="60" mass="7039" checksum="3C1960F63609D216" modified="2016-11-30" version="1">MNPSIIFPTLTLIWHVFTISTYLISTLIDITYLDYVAMISKSEKRPVFRNNYPSKAMNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP75</accession>
    <name>A0A1D3RP75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division topological specificity factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">minE</name>
        <name evidence="4" type="ORF">BAZMOX_19938_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 3">Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the MinE family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000764">
        <property type="protein sequence ID" value="SCN47454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1070.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00262">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005527">
        <property type="entry name" value="MinE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036707">
        <property type="entry name" value="MinE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03776">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55229">
        <property type="entry name" value="SSF55229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01215">
        <property type="entry name" value="minE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="86" mass="9951" checksum="89C3602678158AC3" modified="2016-11-30" version="1">MSLLDYFKTTKPNSAKVAKERLQILVAHERNVRNQPSYLPALQQELLKVIQKYIKVDQDAISVNFDSDDEQETLELNIVLPEHTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP95</accession>
    <name>A0A1D3RP95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coproporphyrinogen III oxidase, oxygen-independent</fullName>
            <ecNumber evidence="2">1.3.98.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_09742_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.3.98.3" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000759">
        <property type="protein sequence ID" value="SCN47442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004558">
        <property type="entry name" value="Coprogen_oxidase_HemN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00538">
        <property type="entry name" value="hemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="294" mass="33205" checksum="6512240D5AAD0200" modified="2016-11-30" version="1">MGFNRISLGVQDFDPAVQQAVNRIQSETQTFAVLESARKEGFRSTSIDLIYGLPLQTVASFSVTLDKILSVEPDRFSIFNYAHLPARFKTQRQINDADMPNAEVKLDILQMIIQCLLEAGYVYIGMDHFAKPGDELAIAQRENKLYRNFQGYSTHSDCDLIGLGITSIGRIADSYVQNVKDLPAYDSLISKGELPVFKGFVLNADDKLRRAVITQLICHFSLSFSNIEQTYSIDFQQYFSTELQVLKVMQDDALLTLNNQEIEVLAVGRLLIRNICMVFDAYVQANTKQFSKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP96</accession>
    <name>A0A1D3RP96_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Biotin carboxylase</fullName>
            <ecNumber evidence="3 9">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_01131_3</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 9">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="3 9"/>
    <dbReference type="EMBL" id="FMJP01000799">
        <property type="protein sequence ID" value="SCN47513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0092">Biotin</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="11">
        <location>
            <begin position="1"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="120"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="447" mass="48609" checksum="D35AC9C5B7421AF2" modified="2016-11-30" version="1">MFDKLVIANRGEIALRILRACRELGVKTVAVYSSADRDLKHVRLADEAICIGPAASVDSYLNIPAIISAAEVTDAEAIHPGYGFLAESAEFSEKVKQSGFIFVGPEADTIRKMGDKIEAKKAMIASGIPCVPGNGEPLGDDNASNLKLAQEIGYPIIIKAAGGGGGRGMRTVHTEGALVSSIALTKSEAGSFFGNSTVYMEKFLEDPRHIEIQVLSDSHGNAIHLGERDCSMQRRHQKVVEEAPAPGITEEQRKFIGERCAQACVDMGYLGAGTFEFLYEKGEFFFIEMNTRVQVEHPVTEMVTGIDIVKEQLRIAAGEPLSYTQDQVVLRGHAIECRLNAEDPKSFMPCPGTIDVFHMPGGPGIRCETHIYNGYRVPPYYDSMIGKLIAHGEDRASAIARMKTALSEMVIDGIKTNIPLQQDIMADSAFALGSQNIHYLEKKLGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA1</accession>
    <name>A0A1D3RPA1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Ornithine carbamoyltransferase</fullName>
            <shortName evidence="5">OTCase</shortName>
            <ecNumber evidence="3 5">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_00271_5</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3 5"/>
    <dbReference type="EMBL" id="FMJP01000628">
        <property type="protein sequence ID" value="SCN47267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="148"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="5">
        <location>
            <begin position="221"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="257"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="299" mass="33608" checksum="FCAA5E06B4B652F4" modified="2016-11-30" version="1">MNPRHFISLLDLSSDEFRALINRAIELKNKRDPNFQPLKGQVLAMIFEKSSTRTRISFETGMTHFGGSAIFLSPRDTQLGRGEPIKDSAKVISSMVDGIMLRTNNHETVTEFAKHSSVPVINGLTDILHPCQLLADMQTYFEHRGDIQGKTVTWIGDGNNMCHSYINAAVRLDFKLNIASPEAYLPNNEMVKSGGERIQLFNQALDAAKDSDLIVTDVWASMGQEEEQKQREIAFKNYQVNQSIMDTAHDDALFMHCLPAHRGEEVTAEVIDGKQSVIYNEAENRLHAQKALLELLMCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA4</accession>
    <name>A0A1D3RPA4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable septum site-determining protein MinC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">minC</name>
        <name evidence="7" type="ORF">BAZMOX_19938_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with MinD and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MinC family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000764">
        <property type="protein sequence ID" value="SCN47452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051302">
        <property type="term" value="P:regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901891">
        <property type="term" value="P:regulation of cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00267">
        <property type="entry name" value="MinC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007874">
        <property type="entry name" value="MinC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="PTHR34108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05209">
        <property type="entry name" value="MinC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="SSF63848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01222">
        <property type="entry name" value="minC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0717">Septation</keyword>
    <feature type="domain" description="MinC_N" evidence="6">
        <location>
            <begin position="15"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="MinC_C" evidence="5">
        <location>
            <begin position="143"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="245" mass="26418" checksum="1C12C1E23CC53B68" modified="2016-11-30" version="1">MSTDSQPISASSPAFEFKSGVITIPVLNLFSTDINVITHQLREKIKQAPEFFTNSSLLLDLSPLQDQELNLALLVDAIRNSGMRPIGVRGGTTSQHQDAKDLMLPIMTSQNSISSKQAAPVKVEIPTQESSEPVASTTIASTVINQPIRSGQRIYVKGDLIIIAQVSAGAEVMAEGNIHIYGSLRGRALAGVQGDESAQIFCSDLQAELVSVAGNYRISEDLDDSNRNTPVQIYLNDQALIIKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB4</accession>
    <name>A0A1D3RPB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_113409_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000787">
        <property type="protein sequence ID" value="SCN47486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="113" mass="12365" checksum="C35556E8881049AB" modified="2016-11-30" version="1">MKQVIAYIKPLKFEHVMLALHKIEGLSGISALEIRGCGRSRKTTSDAIFDEENYGLVSRLKLEIACHDEKVAQVVAVIQESAHTGLRGDGKIYVFPVLEAVRISTGDTGEIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB5</accession>
    <name>A0A1D3RPB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_124587_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000833">
        <property type="protein sequence ID" value="SCN47575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014795">
        <property type="entry name" value="Vibrio_phage_ICP1_Orf50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08681">
        <property type="entry name" value="DUF1778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="54" mass="6240" checksum="4CA322AADEF3D495" modified="2016-11-30" version="1">MQSALEKAESIIEKDKIIYLSNKDAQLFFDMLENPPEPNSKLKNAVKNYRANIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC7</accession>
    <name>A0A1D3RPC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Glutamate synthase [NADPH] large chain</fullName>
            <ecNumber evidence="19">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BAZMOX_02646_0</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="19"/>
    <dbReference type="EMBL" id="FMJP01000823">
        <property type="protein sequence ID" value="SCN47560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="15">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Glu_syn_central" evidence="18">
        <location>
            <begin position="150"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Glu_synthase" evidence="17">
        <location>
            <begin position="628"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="domain" description="GXGXG" evidence="16">
        <location>
            <begin position="1094"/>
            <end position="1263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="SCN47560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="1486" mass="162011" checksum="474395188561FDDB" modified="2016-11-30" version="1">MPPAWENDSTLSADVRAMLEYFSLYEEKNDGPAALIFNDGIRVGARLDRLGLRPLRSVETTEYLAVMSEAGQIDFPSKDVLKRGRIEAGGMIYFDHETGRSYNSHEVMERLAQETDYHALLKARAIHLNDIKPVDFSTLDNQHPFNIDQQHTAYSLNQESFKFLLDPMLSTGLEKISAMGYGITPNALSGSEGGMSRYFSQRFAQVTNPPLDSLRESDGMTLRVALGAKPTFSASTSKQLVINSPVLQRTQLEQIRQQSTVSVITLDALYTPDIENATQNEKNLIQALAEVCNQVGKAAKANTGIIILSDIDISQEKAAIPALLLISAANQHLVKEGLRFNSSLISETGQAVSPHDIATALGFGASAICPLSVHNRVISQYSTGDQQKALDSYQKAVEKSLMKTMGKFGLCTAESYIGGEFFESNYIDTDEPRLKAYFPNINSSVGGVRFADIAASATEWHHKALTVNSESDIPFLGLFKERNEGAGHTFGNTSVREYIHMTDEDILYINQEKSPQVSDKSYTDFGYEKRTPEQIDGFGITPAYRHFTRILMEERDSRPAALRDVMSYPADISRIKETAEFDAILGKQNLYGNINFSIRGLSAQQKDNGVIIKLTNDSSQQRLDNLGAHFKTRFTDSIKLKVLNDTIEVSFNDSDSIVAHYFKNILSARNVISLKQVQPAHEITATLATGAMSHGALLAEAHEAVAQGTNIAGAMSNSGEGGEHSSRFNTLKSSKIKQFASGRFGVWVGYLADLNIEEIEIKIAQGAKPGEGGQLPAAKVSVEIAAARGGTPKVELISPPPHHDTYSIEDLGQLIHDAKAARVRVVVKLVSSEGIGTIAVGVAKAGADVINVAGNTGGTGAAAVTSLKNTGRSPEIGIAEVHQALAVNGLRDKIILRCSGAHQNGSDVVKSAILGGDSFEFGTTALMMLRCVMAKNCNIRCPAGLTTIHEEFKGDPRVLAQYFMNLAHEVREILAALGYQSLAEIRGQTHLLHLINHECMVGQLDFTKLLHHVDVIKVANPVYLEANFSIDDKIIEQFKAGFIDGKQPQVIVEGSEFKLNNCNKTVGGQAAIDIERLLAYQLNDQEIAQHPHIYTNQHKRRYLAADTLIVHTHGSAGQSYGAFNNDGMRMEHTGTCNDGVGKSASGGTIVVLSPGGGHKVPGENVLVGNFTLFGATGGKTFINGEAGDRFAVRNSGAMAVVEGVGDFACEYMTNGAVLNIGTFGKGFCNGMSGGNAYQYDPENKLEHLYDASSVEIRALAEDSDTARAHEQFVIYMLEQHAEYAQSSVAQRLLNNWTTERENFKFAVPLWLYKTQTAEYLAKSVDRKAMIEELAVDQSQQQINQVQQAYLQNSVLFDGLTPSYGETDSLLSFKLVNSFAVLSKATQIAAAQVQSEAETEAAAQRLITTRARKLQDVLVKEAREAYANYNNAQLAIILANKRLNDYKQALILRDVQSTYSLGSTNWIIEQSAINTQALIDIPSVANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD1</accession>
    <name>A0A1D3RPD1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methionine synthase</fullName>
            <ecNumber evidence="6">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BAZMOX_49079_1</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 19">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000796">
        <property type="protein sequence ID" value="SCN47506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="16" id="KW-0170">Cobalt</keyword>
    <keyword evidence="13 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 19 22" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 19 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="14 19" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="20">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="21">
        <location>
            <begin position="147"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="SCN47506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="444" mass="48649" checksum="40831C02B304928D" modified="2016-11-30" version="1">MISGTITDASGRTLSGQTALAFWNSVNHINPISIGFNCALGAQEMRQYVEELSTKVDTYISAHPNAGLPNEFGEYDETPEEMAAEIGDWAKSGYLNIIGGCCGTSPEYIKAIVDAVSPYPPRKIPKIEVRCQLAGLESFSIGKDSLFVNVGERTNVTGSARFKRLIVEEDYDTALDVAREQVINGAQIIDINMDEGMLESKEAMVHFLNLIASEPDISKVPIMIDSSKWDIIEAGLKCIQGKGIVNSISMKEGEDAFIKHAKLVRRYGAAVIVMAFDEEGQADTYDKKVTICQRAYKILVEQVGFPPQDIIFDPNIFAIATGIDEHNNYGVDFIEATREIKRTCPHAMISGGVSNVSFSFRGNNLVREAIHAVFLYHAVQAGMDMGIVNAGQLAIYADVPDELRNAVEDVVLNRIDDGTDKLLEVAEKYRGDAVVNSKTGFRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE2</accession>
    <name>A0A1D3RPE2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Formamidopyrimidine-DNA glycosylase</fullName>
            <shortName evidence="15">Fapy-DNA glycosylase</shortName>
            <ecNumber evidence="15">3.2.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">DNA-(apurinic or apyrimidinic site) lyase MutM</fullName>
            <shortName evidence="15">AP lyase MutM</shortName>
            <ecNumber evidence="15">4.2.99.18</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mutM</name>
        <name evidence="15" type="synonym">fpg</name>
        <name evidence="19" type="ORF">BAZMOX_00594_3</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="15">Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.23" evidence="15"/>
    <dbReference type="EC" id="4.2.99.18" evidence="15"/>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00103">
        <property type="entry name" value="Fapy_DNA_glycosyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 15 19" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 15 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="18">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="17">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA" evidence="15">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for beta-elimination activity" evidence="15">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for delta-elimination activity" evidence="15">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>DNA</name>
            <dbReference type="ChEBI" id="CHEBI:16991"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="SCN47524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="271" mass="30566" checksum="D9465679A60E1E25" modified="2016-11-30" version="1">MPELPEVETSLRGISPHIKNQIVTQVIIRQPQLRWPIPSNLPELLGQQELKSLSRRAKYLLLHFDTGTLLIHLGMSGSLRIVAENTLAAKHDHVDITFANHKTIRLTDPRRFGAVLWLGKKPFEHSLLNKLGPEPLSNSLTGKYLYQKSRNKKVNIKQFLMNQCIVTGIGNIYCTEVLFYAGIRPTRAAGNISLKRYQTLVTHIKRILQTAIEQGGTSLRDFVGSNGKPGYFKQELSTYGRSGLPCQHCQKTLIGIKQANRTTVYCKHCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI0</accession>
    <name>A0A1D3RPI0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hisC</name>
        <name evidence="5" type="ORF">BAZMOX_02140_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000854">
        <property type="protein sequence ID" value="SCN47601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="30"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="362" mass="40564" checksum="0068DDCF83035B09" modified="2016-11-30" version="1">MTEQELITSVIRPEIRALTAYKVADASGFIKLDAMENPYTWPEEIKVEWLKALHDAEINRYPDPEAKSLCRILKEYNQIPADSDLLLGNGSDEIIQLLLMALPANSTVMAPEPSFVMYKQIAQCLGLNYQGVPLLADNFELDLDATLATIKKQQPEIIFLAYPNNPTGNLFDNEAIEQIIQQSKGLVIIDEAYAPFTDFSFIQQLKKYTNLLVMRTVSKLGLAGLRLGFIAGNPAIIRELNKVRLPYNINILTQVSVEFALKHPEMFAEQTNTICTERARMFLQLSVIKEVTPCPSAANFILFRTSIDSATEIFQRLKEQGVLIKNLAPQKGLLNDCLRVTIGKPEENNAFIKALKTALQAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI6</accession>
    <name>A0A1D3RPI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplB</name>
        <name evidence="7" type="ORF">BAZMOX_04315_4</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000822">
        <property type="protein sequence ID" value="SCN47556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="124"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="275" mass="29952" checksum="7511700E2F3D63A3" modified="2016-11-30" version="1">MAIVKSKPTSPGSRFVVRVKHEGLHKGKPFGPLLSKKSKSGGRNNNGRITTRHIGGGHKQSYRVIDFKRNKTDIPGIVERLEYDPNRTANIALVLYKDGERKYIIAPKGVVAGQEIIASENAPVKVGNCMSLRNMPMGSVVHCIELKPGKGAQIARSAGTSAQLIAKDGAHVTLRLRSGEMRKVLADCKAVIGEVSNSEHNLTSLGKAGASRWRGVRPTVRGVVMNPVDHPHGGGEGRTSGGRHPVSPWGMPTKGYKTRKNKRTDKMIVRRRNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI9</accession>
    <name>A0A1D3RPI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_34354_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000813">
        <property type="protein sequence ID" value="SCN47542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024952">
        <property type="entry name" value="Lipo_LPP20-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02169">
        <property type="entry name" value="LPP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="156" mass="17491" checksum="6B721CF74AA0EBC9" modified="2016-11-30" version="1">MGYGTSDIFSNYSPAQRRLMGMRASKMDAYRNLAEQIYGVRIHGHTTVSAMAVQNDSYRTYIDAFLKGARVTSITAVDADTYETVLEITLTPKFFTCLSGTAAIHSQCLNGINSRHNHYSENFSPETKVASLFAYNCNSIDCYKYPDISGFYNKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ3</accession>
    <name>A0A1D3RPJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_79714_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000877">
        <property type="protein sequence ID" value="SCN47620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4432" checksum="D1236A45B47DCECF" modified="2016-11-30" version="1">MFLFVVVSIVVFVVIVRIDFVILLFLFLWFVVVVAMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK9</accession>
    <name>A0A1D3RPK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_30766_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000828">
        <property type="protein sequence ID" value="SCN47562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="12"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="280" mass="32592" checksum="95231B33213CD303" modified="2016-11-30" version="1">MNQEIINQENSKLKIHKHNDLVKARYGALTLPEQLLLLLVIGKVDPRELTPETGVELTVSAFKDLTDANGGSSYDELKKAVKRLYNRSVIILNPDPEDPSLTETETRWVSSINYYKNEGRVRVFFAPKILPYLSNLQSNYTAYFLKHVAKFQSSYSIRLYEMLIQWKSVGSTEIEVDELRQLWMLENKYPAMCDLKKRVIEPALRDINEYSNLWVKVGQRKRGRRVHSLQFRFGLKQQEKKKKQLTREYIENHAKPGESWGDAVSRLKTFAYKCRSGNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS6</accession>
    <name>A0A1D3RPS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type I restriction-modification system, specificity subunit S</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_387374_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000960">
        <property type="protein sequence ID" value="SCN47745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0680">Restriction system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="106" mass="11778" checksum="FF81447DA070970C" modified="2016-11-30" version="1">MNYLFNSDFGLSQLRLIAKGTTSVAAIYYKELKSLIYALPTPKEQVEISSFLDSESEKIGYLIEKSESAIELMQERRTALISAAVTGKIDVRNWQAPNSESKAISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT0</accession>
    <name>A0A1D3RPT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_464333_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000883">
        <property type="protein sequence ID" value="SCN47632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="50" mass="5713" checksum="2F12DBCDBB796298" modified="2016-11-30" version="1">MANFPVAYCGLKIITSLTFRFPDFQRKNNVFGKVCPFKADHDFILCTLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU5</accession>
    <name>A0A1D3RPU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_200851_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000765">
        <property type="protein sequence ID" value="SCN47457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="261" mass="29854" checksum="29A371E1248C3988" modified="2016-11-30" version="1">MGIVRLFAVSFVALILTTGTAYPSRLSIPEAEKQAQVMRDTAYAKAAELRELRKTLNSWWGAQETVNRLQALYYKIATIKYLAQLTFENENSSANAVYDSKHVEKQLLESMKHVAARIPVALASVKPTISHTELLRATDHWSWAKNYLIRAVRLQELVTANHKTNLYHQKISETVEDARIEEGWAHDEYVAMLGVLRYTDDISIDMGLYYSLQAADDYLAQVVRDEEERIEALKSAERNGADEVFNRYLVVLMKSFCRKDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV6</accession>
    <name>A0A1D3RPV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_05330_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000832">
        <property type="protein sequence ID" value="SCN47569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4591" checksum="75FFE8EEAED1C320" modified="2016-11-30" version="1">MQNQHISGEHYSGFWMDIGTPQRLKNLNHFLASNSSDKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW6</accession>
    <name>A0A1D3RPW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_196227_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000928">
        <property type="protein sequence ID" value="SCN47694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025427">
        <property type="entry name" value="DUF4160"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13711">
        <property type="entry name" value="DUF4160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="89" mass="10342" checksum="EB16DF46FA2D4AAF" modified="2016-11-30" version="1">MPTISMFYGIIIRMYFFDNQQHSLPHIHVHYQNYNTIIEVPSGAIIEGKLPKAKQKLVDAWIEIHRDELVANWELAVNGEPIFKIAPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW9</accession>
    <name>A0A1D3RPW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein Smg homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">smg</name>
        <name evidence="2" type="ORF">BAZMOX_01663_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Smg family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000963">
        <property type="protein sequence ID" value="SCN47753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00598">
        <property type="entry name" value="Smg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007456">
        <property type="entry name" value="Smg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38692">
        <property type="entry name" value="PTHR38692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04361">
        <property type="entry name" value="DUF494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="18371" checksum="4877FEED3342ED0B" modified="2016-11-30" version="1">MNEDIFDVLIYLFENYMDSDIDIDSDTDTLKTELKAAGFNSRNIIQAFEWLDMLVQQEEPMFKSNKNFRIFCAEENQKLSVECRDFIYFLQRLDILTPITREFVIDRAMAIDSHQVTLEKVQWISLIVLLNQPDEELAIAHMENIIYQEESDFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY7</accession>
    <name>A0A1D3RPY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 4,6-dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_246182_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000976">
        <property type="protein sequence ID" value="SCN47760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysacc_synt_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="236" mass="26424" checksum="2AC6112A7D66B02E" modified="2016-11-30" version="1">MECIKTNVHGADNVIQASIANNVKKVIALSTDKAANPINLYGATKLCSDKLFVAANNITGDNETIFSVVRYGNVVGSRGSVVPFFKNLITQGVKELPVTDEHMTRFWITLPEGIEFVIKNFQRMRGGEIYIPKIPSMRIMDLVRSIAPDMPIKIVGIRPGEKLHEVMCPKDDSHLTFEFDDHFVIGPSISFTNKDNHFNENELGEKGEPVKQGFEYESGTNPHFLTVEELQEYGNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY8</accession>
    <name>A0A1D3RPY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_70177_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000924">
        <property type="protein sequence ID" value="SCN47682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="191" mass="22012" checksum="5BC7E0116D53BE93" modified="2016-11-30" version="1">MMMQQPNEMLTNQTNCNNMLPANQNNCSNQEMYHQMQGNFNRQKMPQNFNQGNNTVFPPSNMYNQNPPNPQQMWNQQNINPRMPNNQQYSNQMEMSPGCNQVTSSTDREDSAQPIEDFMENINSISSENLLDNMSSVSEHTCTNNFVPQGGNRSESQSSRYSMMSNNMVVNDMSSVLTQLAQENKYLNMRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ2</accession>
    <name>A0A1D3RPZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA polymerase sigma-54 factor RpoN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_06712_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-54 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000943">
        <property type="protein sequence ID" value="SCN47716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00717">
        <property type="entry name" value="SIGMA54_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="10">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="9">
        <location>
            <begin position="130"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="288" mass="32487" checksum="E39741B5696FBC54" modified="2016-11-30" version="1">MAAENLQDCLRLQLLQLSDSTPFKALALELVERFLDILAAQDQVKLMRKLAVSEAKLAEIIALVRSLDPQPGRSIEQSESEYIVPDLFVFKVGGEWRVELNPDIAPKLRVNPFYSGMIKRADNSKDNVNMKEHLQEAKWFIKSLHSRNDTLLRVGRSIIAKQIEFLEHGAIAMKPMVLRDIAEELELHESTISRVTTQKYMHLPNGVIEFKYFFSSHVSTSAGGECSATAIRAFIEELVSTENPAKPLSDSKIADLLKEKGINVARRTIAKYREAISIPSSSQRKRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ09</accession>
    <name>A0A1D3RQ09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-succinyl-L,L-diaminopimelate desuccinylase</fullName>
            <ecNumber evidence="1">3.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00742_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000881">
        <property type="protein sequence ID" value="SCN47629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4821" checksum="BD626A2F378E4EDC" modified="2016-11-30" version="1">MIELGPLNESIHKLNENVGLEDLEILSKIYEQILIELLVTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ15</accession>
    <name>A0A1D3RQ15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus biogenesis protein PilF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_08843_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000953">
        <property type="protein sequence ID" value="SCN47736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="16"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="222" mass="25891" checksum="01F3907406B796D1" modified="2016-11-30" version="1">MQPDKVAVERPAKERAQTLADLGLAYYQLEKYTYALEYLKESLALDTNNAQTYQVMGLINMRQNLPDQAQISFAKALHVEPDNFDILTDYAVFLYGQERYAEALSTFKRIVKAPFYKRKWVAYTYLGLYDLKNSQKREAEKKFYYALKINKNYAPALLEMAKIRYSKGEMMAARAFIERYFANAGKTLEGLRLAVKVERALQDDDMAEQYQLELKHTYPYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ40</accession>
    <name>A0A1D3RQ40_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsD</name>
        <name evidence="10" type="ORF">BAZMOX_00676_3</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="9">
        <location>
            <begin position="3"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="8">
        <location>
            <begin position="96"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="206" mass="23320" checksum="07F437C537B50B52" modified="2016-11-30" version="1">MARYLGPTCKLSRREGTDLFLKSRGKSLEGKCKLDQRPGQHGTKRARDSNYASQLRAKQRIRRIYGVLEKQFRNYYKAAELQKGATGLNLLNLLESRLDNVVYRMGFAATRAEARQLVSHKSILLNDSILNIPSAQVNVGDKISIREKSKKQVRIIDSLTVADQYGFPAWLEVNPKEFTGSFNSLPDRADLGSDINEQLVVELYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ51</accession>
    <name>A0A1D3RQ51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_30428_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001017">
        <property type="protein sequence ID" value="SCN47823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920283" evidence="2">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="84" mass="9519" checksum="571BF1C39F8BA1AA" modified="2016-11-30" version="1">MQHVYKSIIVLLLSATASMSVYAQYKPMNINTSKNTSKSMNMGMSEEMKDRQAQAIQKYILQRDELSDQIRDEKNSAKNASIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ53</accession>
    <name>A0A1D3RQ53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate dehydrogenase hydrophobic membrane anchor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BAZMOX_49357_1</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Membrane-anchoring subunit of succinate dehydrogenase (SDH).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000831">
        <property type="protein sequence ID" value="SCN47567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014312">
        <property type="entry name" value="Succ_DH_anchor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02968">
        <property type="entry name" value="succ_dehyd_anc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN47567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="127" mass="14305" checksum="988BAFBA983227B6" modified="2016-11-30" version="1">MEYQTPLAKARGLGSAKSGTKHWWMQRVTAVALIPLSFWLILFVQQLFHASYPEIKQWLVSPLNFTLLIAWAFVGFYHAALGLQVVIEDYLSPEWLKIVTVWLVKLTFMGAAIAALVFAIRIAISVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ58</accession>
    <name>A0A1D3RQ58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_178563_0</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001065">
        <property type="protein sequence ID" value="SCN47885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024108">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF1">
        <property type="entry name" value="PTHR11766:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="11">
        <location>
            <begin position="173"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="236" mass="26444" checksum="BA7A441C7C9761B1" modified="2016-11-30" version="1">MKFLYPLVQGYDSVAMEADIELGGTDQKFNLLMGRTLQGYYGKPQQCTLTMPILEGLGGVQKMSKSLNNYIGIRDEPNDMFGKIMSISDELMWRYFELLSFRPMEEITGWRRECEEGANPRNYKVKLAQEIIARFHSEVAAVKALKDFEAQFKRGAIPDDITEIELTASGEGYAIALLLKDAGLTVSTSDSNRMVKQGAVKYDGEKITDAKLVVPVGAEHVFQVGKRKFAKVKIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ59</accession>
    <name>A0A1D3RQ59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_30273_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001000">
        <property type="protein sequence ID" value="SCN47794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4754" checksum="8B9D39C02C2807F3" modified="2016-11-30" version="1">MFFFVFSGYGRAYFSCTSAHTCTGDGTAMVTSNVLLCFQWLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ76</accession>
    <name>A0A1D3RQ76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_07964_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000929">
        <property type="protein sequence ID" value="SCN47699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="106" mass="11509" checksum="8C331AB13BA28906" modified="2016-11-30" version="1">MEIHSSSLYIAPSGQTTQSTSRSSNAAQLDNTLDKPNNVQQRLSKSDEFATATQKKQTQQLLVSAPPNNEALSTRTAKALGTYASTYNQIPQQQIASTITGIDFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC3</accession>
    <name>A0A1D3RQC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P) transhydrogenase alpha subunit</fullName>
            <ecNumber evidence="2">1.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11819_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001070">
        <property type="protein sequence ID" value="SCN47891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="1">
        <location>
            <begin position="55"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="213" mass="23451" checksum="B5D9E4E75F6C124F" modified="2016-11-30" version="1">MLFRVPTTSLLVNLGSSVEKLSIQCSRGFKNAPRNYCQKAEKTVNGIPYKNLTVGIPKETFLNEKRVAISPAAVANLIKKGFNVSVEKDAGIEAKFTNSDYETAGAKILSAQDAFKSDIVLKVRAPTDKELPLFKDNATLISFLYPKQNQDLVEKLATHNLNAFAMDMIPRISRAQVFDALSSMANIAGYKAVIEAANNFGRFFTGMSEYLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE8</accession>
    <name>A0A1D3RQE8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_55186_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000910">
        <property type="protein sequence ID" value="SCN47667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="91"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="174" mass="19837" checksum="62AFED093E4A32FF" modified="2016-11-30" version="1">MAFTAQFELLDPKLHANKVFDCGHDEMNQFLRRYADKNRNLGLSSTWVLPEKVEGNSEQKIKLGAYYTLASSTVKQEDIPYDKKLPAYPVPVVLLARIAVNRHYQKQGLGKKTLITALRKALELTEKGLPALGVVLDVLDNNALSFYQKFDDFQPFDNNSMRLFISMKVIRQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQI7</accession>
    <name>A0A1D3RQI7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5 6">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="7" type="ORF">BAZMOX_12411_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5 6"/>
    <dbReference type="EMBL" id="FMJP01001086">
        <property type="protein sequence ID" value="SCN47916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="197" mass="21653" checksum="64896AE738E83B29" modified="2016-11-30" version="1">MTDRTASIERNTLETQISISINLDGTGKAKFDTGVPFLEHMLDQIARHGMIDMDVTCKGDLQIDDHHTVEDVGITLGKAFAKALGNKKGLVRYGHAYVPLDESLSRVVIDFSGRPGLYYEVHFSRAMIGAFDVDLLREFFQGFVNHAGVSLHIDNLKGVNAHHIAETVFKAMGRALRMAVAEDPRMAGIMPSTKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQK9</accession>
    <name>A0A1D3RQK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="11">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rlmN</name>
        <name evidence="13" type="ORF">BAZMOX_08843_2</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="11"/>
    <dbReference type="EMBL" id="FMJP01000953">
        <property type="protein sequence ID" value="SCN47737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="68"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="131"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="185"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="11">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="329" mass="36242" checksum="945D40E3E7018136" modified="2016-11-30" version="1">MIKWIYQEGEFDFDKMSNLSKSLRAYLNEHCCIVAPEIILEQVASDGTRKWIVEMGGGNKVEAVYIPEATRATLCVSSQVGCALACTFCSTAQQGFNRNLTTAEIIGQLMAANARMGAEGRVTNVVMMGMGEPLLNFDNVVPAMNLMTEDFAFGLSKRRVTISTSGVVPAMYRLTEVCDISMAVSLHASTDELRDILVPINQKYPLKELMAACKKYIEGSPRGFITFEYVMLEGINDSVADARALVKLLKNVPSKMNLIPFNPFPNTQYRCSSKAAIEQFRDVVHKAGIITTVRKTRGEDIGAACGQLVGKVLDKSRRAERLQKMGLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQN0</accession>
    <name>A0A1D3RQN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maturase integron/retron-type RNA-directed DNA polymerase (Reverse transcriptase) part of type II intron</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_52771_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000981">
        <property type="protein sequence ID" value="SCN47767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000123">
        <property type="entry name" value="Reverse_transcriptase_msDNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00866">
        <property type="entry name" value="RNADNAPOLMS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="397" mass="45764" checksum="C96653EA69C70C37" modified="2016-11-30" version="1">MKQNKGAAGVDGLTIEDYPVWIHQHWADIQRGLQQGYYCPLPVKRVEIPKPNGGVRLLGIPSVHDRVIQQAITQVLQPLIDPDFSDHSHGFRPNRSAHDAVKSVQKGIKDGYGYAVDIDLSKFFDKVDHDLLMNRLGKWVTDKQLLALIGKYLRAEVSIKGQREPTRCGVPQGGPLSPLLANIMLDDLDRYLESKGYRFARYADDFVISVKSLTEGERIKTEVTAYLETLKLPINTEKSQVVSSQHLCFLGFAFKGKKIVWSPKSLANFKHRIRELTGRSWGVSWAYRYEKLRQYIQGWGNYFGLSEYYRPIPLLDQWIRRRIRMCYLKQWRRIRTRIHNLMRLGVPKSAAISLGMSSKGYYRLAKTKAVQLALNNKWLESQGLVSIKDQWVKFHYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQQ0</accession>
    <name>A0A1D3RQQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_551499_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001081">
        <property type="protein sequence ID" value="SCN47909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="47" mass="5018" checksum="54D5053FCD90200B" modified="2016-11-30" version="1">MNLNALKNTEELQSFLDGSPAVAFGYVASIIENEHALSSGITILLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQS7</accession>
    <name>A0A1D3RQS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oxaloacetate decarboxylase beta chain</fullName>
            <ecNumber evidence="8">4.1.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_08831_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.1.1.3" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01001024">
        <property type="protein sequence ID" value="SCN47837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005661">
        <property type="entry name" value="OadB_MmdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35806">
        <property type="entry name" value="PTHR35806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03977">
        <property type="entry name" value="OAD_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01109">
        <property type="entry name" value="Na_pump_decarbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="274" mass="29505" checksum="052434555FDD24C1" modified="2016-11-30" version="1">MENLLSLWHSTGLYNFTLPQVIMMLVGFLLLYLAIKKGFEPLLLVPIGFGAVLSNIPVAGLAEEGGLLYYLYYGIKTGIFPLLIFMGVGAMTDFGPMLANPKTLLLGAAAQFGIFATLLGALALNMIPGLEYSLSDAAAIAIIGGADGPTAIYVASKLAPDLLGAIAVAAYSYMALVPLIQPPIMRALTTPEERSIEMQQLRFVGKAEKIIFPLMLLILTALLLPSAAPLVGMFCLGNLMNVCGVVERLSKTSQNELINMLLFSRFIRWLQNEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQZ8</accession>
    <name>A0A1D3RQZ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="7" type="ORF">BAZMOX_52815_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001080">
        <property type="protein sequence ID" value="SCN47907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="57"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="123" mass="12510" checksum="A252270565DCA160" modified="2016-11-30" version="1">MAISQEDILEAVSNMTVMEIVDLISAMEEKFGVLAAALAAGPAAGGDAAAAEEKTDFDVVMTSFGANKVTVIKAVRAITGLGLKEAKGAVEGCPTVLKEGVSKEDAEAVKAQLEEAGASVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL55</accession>
    <name>A0A1D3RL55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01013_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000006">
        <property type="protein sequence ID" value="SCN46396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="134" mass="15965" checksum="F7DCB1A0A338CFB8" modified="2016-11-30" version="1">MDQEYFNKRKKKFLMQSAIWYVFLALLTYFLPKVMLFYVVCGLYDVTRNSNIDGRMLYRYFFGNGVPTWALSPFNILMDVLTLPYINKKIYQLEDLPEDCQAEIKHILDVVKSENIVDELSSRMEKIKRGMSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL85</accession>
    <name>A0A1D3RL85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_144645_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000027">
        <property type="protein sequence ID" value="SCN46426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="53" mass="6308" checksum="6CB257C47C5DD1F2" modified="2016-11-30" version="1">MQSVLDNKIKGINVIATKMILHLKHQKETLLPANLHRTALSVFIYLRMWNDWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLC9</accession>
    <name>A0A1D3RLC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_208044_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000059">
        <property type="protein sequence ID" value="SCN46466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="52" mass="5694" checksum="BCA48EFCE080E7D4" modified="2016-11-30" version="1">MGHSLGLIVIAEGVETVEQQAFLAQEGCDLIQGYLLSRPLTVEQFSDLFKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLE9</accession>
    <name>A0A1D3RLE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PUTATIVE PERIPLASMIC PROTEIN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04566_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000071">
        <property type="protein sequence ID" value="SCN46486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016907">
        <property type="entry name" value="UCP029033"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029033">
        <property type="entry name" value="UCP029033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="238" mass="26701" checksum="CCD23E66C4029934" modified="2016-11-30" version="1">MQENSKVNVFILGFFIFLGLFALGYLLANAAIKVKEYERTVTAKGLSEREYPADIIIWPIQFTEASNELIKLYSSVDASSLKIKHFLQKKGISEKEISFSSPVITDKSAQQYGNAKAEFRYTAMQTITVYSENIKGVRAIMSSLSELGKSGIAFTGNNYQSQTKYIFTRLNDVKPDMIEEATKQAREVAQKFAADSQSQLGKIRKASQGQFSISARDQNSPHIKKVRVVSTVEYYLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLG5</accession>
    <name>A0A1D3RLG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Secretion protein HlyD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_22207_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000095">
        <property type="protein sequence ID" value="SCN46513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="281" mass="31668" checksum="C2B68E51B6BC7378" modified="2016-11-30" version="1">MPIASEISGKVTHIYADIGQPIPENGIFACLDDTFIKLDIASTENSIAQHGIDLKFLSKQVGRHKKLVKSNSAAISLLDDLTRQKGNAYRAIQNEKIRKQKQQETKNRHCIKAPKNWKITQRNIEPGQWITAGNTIAQASDYSQLLIPITLTTEELAALQAQVKLSVYLPEYQQKIPVSIEHISPEFDPQSHKILVNLVIKDTSKYQRGGIRAELTLNVSDKLNNFLIPKDALDARFEEVWLTRKNGERIRVMLQGYADSNTAKISSAEIKIGDQFKRQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLG8</accession>
    <name>A0A1D3RLG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03205_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000127">
        <property type="protein sequence ID" value="SCN46555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="208" mass="22624" checksum="079F804557C4612E" modified="2016-11-30" version="1">MLDRNEVEIPCWRHALISFPHPLLKEGLCILDTPGLNALGTEPELTLNMLPSAQAIIFVLAADTGVTKSDLEMWRNHISIARGTGKQGLAVVMNKIDSMWDDLAGDAGYDASIASQVKNSASILGVSEELIFPVSAKQALLAKIKSDDALLEKSRLAGLENYLSDNILQHRRTILMETVAHNIGFLVKESLSLTEIKYKKCNGSIGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLI1</accession>
    <name>A0A1D3RLI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00699_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000100">
        <property type="protein sequence ID" value="SCN46522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="172" mass="19253" checksum="DB32BC729CC70B44" modified="2016-11-30" version="1">MYNKLQTVLPLDVDTEDGKQFSFSGDINTLEFVAAMPASAARLGLQIFKLSLIPSKNNQGKELMVDIKPFFGQSDETSWKEEQVVILKNVQRLHFAYFNADDTKDDAGWQKEWLDKFELPDLVSVDIELMNGELWPQIVVELKVDDVAAGGAAVGKRGRNPFGIVNGKFTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLJ3</accession>
    <name>A0A1D3RLJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_16396_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000110">
        <property type="protein sequence ID" value="SCN46532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="211" mass="22633" checksum="4F05985BCE77899C" modified="2016-11-30" version="1">MILELIYSRIGASPKRIVQPAAERSAEASDNSNACSTFKSGKPSISKIRPEKTFFLPFFSTVNKPFSIAAKGIALTKSRKVMPACISPVKRTKTDSGISKGMTPVAAANATKPEPAGKEMPIGKRVCESPPVPTVSGNNIRFNQEWIIPSPGRRATPPRFIIKSGKLCCIATSMGFGYAAVWQKDCSTKSAEKPKQAKSFNSSRVIGPVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLJ9</accession>
    <name>A0A1D3RLJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01011_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000111">
        <property type="protein sequence ID" value="SCN46536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4205" checksum="3AC26A01A7D02B74" modified="2016-11-30" version="1">MARRLTLKTIGFGHAKLYLEIQPSCDKALHASGYWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK7</accession>
    <name>A0A1D3RLK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_265722_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000132">
        <property type="protein sequence ID" value="SCN46561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40588">
        <property type="entry name" value="PTHR40588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006156">
        <property type="entry name" value="YafQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="88" mass="10287" checksum="B4D704271033F24B" modified="2016-11-30" version="1">MKIKRHKTFIKDFKKVQITDGQFEKFIQFINCLRENSPLPEESKDHALNGEYSDCREFHLGGDTLVIYLVIDNEATLMRIGSHAQLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN5</accession>
    <name>A0A1D3RLN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_331915_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000146">
        <property type="protein sequence ID" value="SCN46576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5428" checksum="FEFE6267E14CE406" modified="2016-11-30" version="1">MNTATKKPGLQALAFSTAIQRILHFFTFSHAQFPPGTLSPAENQGNGALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR8</accession>
    <name>A0A1D3RLR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General secretion pathway protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_00699_2</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000100">
        <property type="protein sequence ID" value="SCN46519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="GspH" evidence="9">
        <location>
            <begin position="31"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="134" mass="14667" checksum="A254892786631670" modified="2016-11-30" version="1">MVIVIIAISAAVVAPNIGSGNQTAKLKSSMRDIASALRFARGHALSQHKESRVLFNLQDNTYQITGKTKTYRIAKEIEVTLDLAQSQIIDETQGSIRFFPDGSSTGGRVTLEVAGNKRQLDINWLTGHVEINDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR9</accession>
    <name>A0A1D3RLR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_393567_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000190">
        <property type="protein sequence ID" value="SCN46645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="73" mass="8340" checksum="C93BA91E11E80AEB" modified="2016-11-30" version="1">MPKKILVIDDAPYVQQFTNALTEKGYLIFAISPGTDLYQVIHQEQPDLVIIDAFYNHSSILLKLNHLSLLQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU8</accession>
    <name>A0A1D3RLU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase IS3/IS911 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_412652_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000209">
        <property type="protein sequence ID" value="SCN46675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="109" mass="12470" checksum="AA2AA5EC81EFAC14" modified="2016-11-30" version="1">MSLEVNMSNKNKQTKPKYTLEFKQDAAKLVIKHGYTQQQAADHLGVSLSAIRRWVKAEKGPEEKTIKNNSSLNLSGHDELLQLRKENKQLCMEREILKKAAVFFAKEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW0</accession>
    <name>A0A1D3RLW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_161981_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000195">
        <property type="protein sequence ID" value="SCN46650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="287" mass="32625" checksum="F8708011952B9312" modified="2016-11-30" version="1">MISVVIVIYLFLPFHSLTKLPNKKQVATTSTRSVVKDDEYLRNMSWPTEEIDKQELNRLYELGNTATPRDLRDIEFYEQGGLVSSTPEMMELSKEGVEFIKNRFRLMDNQGYYEVDFVDDLTINMGGSFKVKKILKALGASNYHEGIQNVNEHLSFIATDLDNSLFVNIPHLVSQTYGSLSFDRWSSVKHFFEDPELGIVRLSEQRSGPAGETMYILPVELNEEINGNPARYTVEVSPNGKAKTTLRWVNGIIMYTLIMQKNAGINNEAKSYFFELARSLPIGGGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW3</accession>
    <name>A0A1D3RLW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oligoketide cyclase/dehydratase or lipid transport protein YfjG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00299_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="PTHR12901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="1">
        <location>
            <begin position="11"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="144" mass="16078" checksum="9F651BCB6EAD16C3" modified="2016-11-30" version="1">MAIVEKSALVKFSAQQMFALVADIESYPEFLPWCTGSRIISREGNVVEAELQIAKAGFKHAFATRNINDESELRITISLLHGPFSSLDGVWSFMPLREDASKISLDLEFEMNGVLANFAFGAVFNQICNTMVTSFTERAKQIYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW8</accession>
    <name>A0A1D3RLW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipoprotein releasing system transmembrane protein LolC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_00299_8</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011925">
        <property type="entry name" value="LolCE_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02212">
        <property type="entry name" value="lolCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="10">
        <location>
            <begin position="27"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="302"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="415" mass="45490" checksum="2B61F9F4EE587831" modified="2016-11-30" version="1">MFKPLTLYIGLRYTRAKRRTQFISFITLTSVLGIALGVTALITVLSVMNGFEAELRQRILGMTAHSTVTGRGGQLDDWQVLEKELQNFPHVQGTAPFVNGQVMVNAGRRVSGTALRGILPEQESAVSEVGEKMQIGALTDLQAGKYQIVLGSELATYLGVIVGDKVTVISPQVNSTPAGIIPRLRRFTVSGIFEVGMYEYDRNMAIIHIVDAAKLLRMEGRVSGLRLKLDDLFNAPQISRELAEKLRGQYYVSDWTKAHSNFFRAIQTEKRVMFIILLLIVAVAAFNIVSTLVMVVTDKRGDIAILKTQGLTPLSVMGIFITLGSIIGLIGTALGTVGGVLLALNVETIVPAIEKFFGVNFMAADVYYISSLPSKLVWMDVYVIAIVAFSLSLLATIYPAWQASRVNPAEVLRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX4</accession>
    <name>A0A1D3RLX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismatase</fullName>
            <ecNumber evidence="2">3.3.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00299_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.3.2.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008908">
        <property type="term" value="F:isochorismatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="188" mass="20851" checksum="626BA17A622827D6" modified="2016-11-30" version="1">MTTHPNLLDSQNSLLLIVDIQDKLTGAMPEGNAEDMLENSSRLITAANLLNVPIIITEQYPKGLGATVASIREKLNASTTHFEKTGFSCLAADNFSATLEKKARKQIIIVGQETHVCILQTALELMQQGYQVHIVEDAVCSRKAENKFYALQRLQTQGATISNFESVLFEWLKNSQHEHFPAIAALLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX9</accession>
    <name>A0A1D3RLX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_204940_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000150">
        <property type="protein sequence ID" value="SCN46579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920248" evidence="1">
        <location>
            <begin position="21"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="132" mass="14394" checksum="3564871FF78F7AEA" modified="2016-11-30" version="1">MKKLLPALLILPMFSTTILADSALDGDNNLDGNSTTKVTSERYDFNLLVKKVSSNTQGIAIANRKIGGNANAIGATNNKVINNKNNIKKLDIDNKQVVEEICASSIENALIWARLTAIEIKLNKLIKSKNQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ8</accession>
    <name>A0A1D3RLZ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_18123_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000225">
        <property type="protein sequence ID" value="SCN46701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="157"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="204" mass="22197" checksum="04DB2A5F563FCBCB" modified="2016-11-30" version="1">MLLPNSQKIILASGNKGKIKEIQALLKDYTIVTQQEFNIQEAEETGSTFVENAIIKARNAAHQSNLPAIADDSGLVVDALNGAPGVRSARFAGPQANDQENLQKLLKDMEGIPEAQRTARFICVIVLMRHVNDPFPIITQASWEGIILDKAQGTNGFGYDPIFLIPTENCSSAELPASKKNSVKPPRASTKEIKQFSISVNNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM37</accession>
    <name>A0A1D3RM37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <ecNumber evidence="3">2.7.1.148</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_09208_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.1.148" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000141">
        <property type="protein sequence ID" value="SCN46568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_C" evidence="2">
        <location>
            <begin position="95"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="174" mass="19184" checksum="EF4F79715BBA04D1" modified="2016-11-30" version="1">MVVLNQLWQLGLSKQRLMGLGVKLGADVPVFVNGASVWAEGVGEQLTEINLPEAWFVIVKPDCHVDTGEIFSTKGLTRGSKSIKMSEFQSGQVKNDCQEVVENIHSEVKEALAELSQYGNSRLTGTGACVFVQFDNKLSAENVYNKLNSKREVYLAKGLAISPLQKQMSELFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM69</accession>
    <name>A0A1D3RM69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Particulate methane monooxygenase A-subunit</fullName>
            <ecNumber evidence="2">1.14.13.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00686_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.14.13.25" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000262">
        <property type="protein sequence ID" value="SCN46754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106317">
        <property type="term" value="F:methane monooxygenase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106318">
        <property type="term" value="F:methane monooxygenase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037001">
        <property type="entry name" value="NH3/CH4_mOase_suA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003393">
        <property type="entry name" value="NH3_CH4_mOase_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02461">
        <property type="entry name" value="AMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03080">
        <property type="entry name" value="CH4_NH3mon_ox_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="249" mass="28500" checksum="E0AF37CFB49BC908" modified="2016-11-30" version="1">MSASQSAVRSRAEAVQVSRTLDWMILFTLFTAVLGGYHIHYMLTGGDWDFWSDWKDRRLWVTVAPIVSITFPAAVQAMLWYRYRLPFGAIVCVLALMLGEWINRYLNFWGWTYFPVNFCFPSNLIPGAILLDVVLMLSSSFVLTAVVGGMAWGLVFYPGNWPIIAPLHVPVEYNGMMFTLADLQGYHYVRTGTPEYIRMVEKGTLRTFGKDVAPVSAFFSAFVSIIIYFLWHYFGRWFNKTDFISGEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM81</accession>
    <name>A0A1D3RM81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_405956_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000175">
        <property type="protein sequence ID" value="SCN46618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920251" evidence="1">
        <location>
            <begin position="21"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="74" mass="7870" checksum="F8AF71E645C1049A" modified="2016-11-30" version="1">MNKLQSLSILVLAVFISACAPSLTKDIEVDAASDPKVNLTAYTTYAWNGAVILFNDPEGQWATAENRGNGALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM82</accession>
    <name>A0A1D3RM82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_86853_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000300">
        <property type="protein sequence ID" value="SCN46805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4786" checksum="ECEF313B049AF583" modified="2016-11-30" version="1">MMGFKAFHSAQATTAGIETAHMIRKGQLSEENIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM99</accession>
    <name>A0A1D3RM99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chaperone protein DnaK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_243452_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000186">
        <property type="protein sequence ID" value="SCN46638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="149" mass="16569" checksum="7AA521B8A6A40E15" modified="2016-11-30" version="1">MDIIANDQGNRTTPSYVAFTDTERLVGDAAKNQVAMNPENSIFDAKRLIGRNYSDQTVQSDMKHWPFTVVNHGGKPKLQAEYKGERKTFTPEEISSMVLVKMKETAEAYLGQKVTDAVITVPAYFNDAQRLATKDAGMIAGLECAENYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB1</accession>
    <name>A0A1D3RMB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00523_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5475" checksum="7F8BB25FCB188DB2" modified="2016-11-30" version="1">MSKDEKENHLRVFKDRSEYIIDGEDKEIFGKALCQPKQKENKTYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB8</accession>
    <name>A0A1D3RMB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_205735_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000167">
        <property type="protein sequence ID" value="SCN46607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="77" mass="8600" checksum="1D64BC1FCFB36116" modified="2016-11-30" version="1">MNQLITIDISSETPKGLGLKEYKSHPRIGEWIEMNINETGNMFEVVMIAHSDSGDGSDVYVKKLGETPSVIKTIYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC3</accession>
    <name>A0A1D3RMC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ORF">BAZMOX_05000_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="FMJP01000317">
        <property type="protein sequence ID" value="SCN46841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="291" mass="31257" checksum="AA46C0B0B3308EC8" modified="2016-11-30" version="1">MIQGSIVALVTPMFDNGDIDKDSLKKLVEFHIEQGTDAIVSMGTTGESATLNEQEHMDVVKSVIQYVAGRIPVIAGTGANSTSEAIALTQAAKEVGADACLLVTPYYNKPTQEGLFLHYKAIAEAIDIPQILYNVPGRTACDMLPETVGRLAKIKNIVGVKEATGDLSRVTVIRELCGDEFAIYTGDDASSCEFCLLGGNGTITVSGNVAPRLVHEMITAAMNGDRETATSVDALLKGLHKYLFIQSNPIPVKWAVAEMGLISHGVRLPLTWLTEDCVDKVRKAMKQAHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME3</accession>
    <name>A0A1D3RME3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonucleotide reductase of class II (Coenzyme B12-dependent)</fullName>
            <ecNumber evidence="2">1.17.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02006_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.17.4.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000332">
        <property type="protein sequence ID" value="SCN46861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIBORED_LARGE" evidence="1">
        <location>
            <begin position="105"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="366" mass="40609" checksum="00CC34F32756EA8C" modified="2016-11-30" version="1">MTNKAHTNTMEIALQDASLDIWDTKYRLKTKSGEAVDANIDGTYQRVAKALSSVEKGKAKQEKYYQEFLWALRQGVIPAGRIISNAGAQDHKPATSTINCTVSGSIVDSMDDILGKVHEAGLTLKAGCGIGYEFSTLRPKDAYVSGAGAYTSGPLSFMDIYDKMCFTVSSAGGRRGAQMATFDIGHPDVVEFIRAKREDGRLRQFNLSLLITTEFIEAVKADKPWSLSFPIMQRELEQDNLDLTDKSLIIWRDLPHSLGYVENEEGLVACKITKTLPARRLWDIIMSSTYDYAEPGFILIDKVNEMNNNWFCEDIRATNPCVTADTWVQTEHGARQVSSLLGQQIKVLVDGQLHLSGAQGFFQDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME8</accession>
    <name>A0A1D3RME8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_127535_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000328">
        <property type="protein sequence ID" value="SCN46852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="110" mass="12406" checksum="39048307C1A8AF68" modified="2016-11-30" version="1">MIDVRTKVEHGFVGHPLAAVHIPWKEFPDWQVNTQFVEQVKVAVNNDVTRPVLLLCRSGQRSLDAAQALNEAGFAHSINILDGFEGALDDNKHRGNLSGWRYCQLPWEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF4</accession>
    <name>A0A1D3RMF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03539_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000250">
        <property type="protein sequence ID" value="SCN46739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4292" checksum="8157E19098C6935E" modified="2016-11-30" version="1">MIFPRLLTALLFSLLIACGQQGPLFMPIEDTKTQQGDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMH9</accession>
    <name>A0A1D3RMH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_23179_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000358">
        <property type="protein sequence ID" value="SCN46905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="159" mass="17162" checksum="6ED3B51DFB24855C" modified="2016-11-30" version="1">MEKLLQKQRASGGGDYPEAMEQGLEQALSAPWHTGSTARVAFLVADAPPHDENLLPMLTLSHTAREKGVHIYSLAASGVADTAEYLMRSISVLTHSRYLFLTDDSGVGNSHAIPTVPCYQITKLNASIIRAIESELAGQRIEEAIKEVGLQQDGQCSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML4</accession>
    <name>A0A1D3RML4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome c heme lyase subunit CcmF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_01705_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000295">
        <property type="protein sequence ID" value="SCN46799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032523">
        <property type="entry name" value="CcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003567">
        <property type="entry name" value="Cyt_c_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003568">
        <property type="entry name" value="Cyt_c_biogenesis_CcmF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43653">
        <property type="entry name" value="PTHR43653"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16327">
        <property type="entry name" value="CcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01410">
        <property type="entry name" value="CCBIOGENESIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01411">
        <property type="entry name" value="CCMFBIOGNSIS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00353">
        <property type="entry name" value="nrfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="620"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="8">
        <location>
            <begin position="89"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="CcmF_C" evidence="9">
        <location>
            <begin position="316"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="652" mass="71942" checksum="AFF138F4A7556F16" modified="2016-11-30" version="1">MIPELGEFALILALGFSFILAVVPLYGAATLNALWMDYAKPLAKAQFTFLLISFMCLAYAFANDDFSVQYVANHSNSQLPIQFKLSAIWGGHEGSLLLWAFILSGWTLAVSLFSRGLPLDMLARVLGVMGIIATGFISFLLWTSSPFLRYLPRFPADGADLNPLLQDFGLIVHPPMLYMGYVGFSVAFAFAIAALLSGRLDAAWARWSRPWTNIAWAFLGAGITLGSWWAYYELGWGGWWFWDPVENASLMPWLVGTALIHSLAVTEKRGVFKSWTLLLAIFAFSLSLLGTFLVRSGVLTSVHAFASDPERGFFILVLLLLTIGGSLTLYAFKAPNVKSESSFGWLSREMLLLINNVFLVVMAITVLLGTLYPLLIDALGSGKLSVGPPYFNALFVPIMSLLALSMGISGAARWRQTSIAGLKKQLFVPAIISLVVGLVFPFIYGDGFNFRVFLGITISTWIIATTAKEFKDKFRNTNSITAKLSQLTLSYYGMMLAHLGVAVVAIGITLVPTYSEERDMRMAPGDKIELADYQFEFKGAKKVKGANFTADEGTIVITLEGEPVVTLYPQKRHYTVKRSMMTEASIDPGLFRDLYLAMGEPLGNDGAWAIRVHYKPYVRWLWLGGLLMALGGLLTVFDKRYRSKSSSEVAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMU7</accession>
    <name>A0A1D3RMU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Squalene--hopene cyclase</fullName>
            <ecNumber evidence="2">5.4.99.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01616_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="5.4.99.17" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000313">
        <property type="protein sequence ID" value="SCN46828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051007">
        <property type="term" value="F:squalene-hopene cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SQHop_cyclase_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="7862" checksum="CED7E1B9831C3901" modified="2016-11-30" version="1">MAAGETDTQEVKAGISYLLNSQTEEGVWADECHTAPGFPRVFYLKYHGYDKFFPLWALARYRNEQNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN12</accession>
    <name>A0A1D3RN12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_57597_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000325">
        <property type="protein sequence ID" value="SCN46847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="86" mass="9690" checksum="1434380BBB97B487" modified="2016-11-30" version="1">MIAKQSPEYEKITQVRDALCHNSANISFAAKLWQVFKAIITGALDALKTLLGDAITLVMETIEAHIQYFFVQVLQLDPKMLRLEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN31</accession>
    <name>A0A1D3RN31_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_12464_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000493">
        <property type="protein sequence ID" value="SCN47082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09873">
        <property type="entry name" value="PIN_Pae0151-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044153">
        <property type="entry name" value="PIN_Pae0151-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="143" mass="15973" checksum="724122D4CE026218" modified="2016-11-30" version="1">MQKYVIDSSVFNKLYLDEIDRDKAKQLFIQAAAGKVILIAPDLLYLEVVNTAQRCGVPIDSVVELLEAQKYLLQIRAVSDSERKKAIEIIATGHIKSGYPSIYDALFHAMALCNKAVFVTADKHHYAKTQILGNICLLSELSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN42</accession>
    <name>A0A1D3RN42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I restriction-modification system, restriction subunit R</fullName>
            <ecNumber evidence="1">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_161123_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.21.3" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000369">
        <property type="protein sequence ID" value="SCN46918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4408" checksum="BFB83988D718667F" modified="2016-11-30" version="1">MLTTEPLVMRPYQIAATERILWKINSAYQGKNCSHTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN52</accession>
    <name>A0A1D3RN52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inactive homolog of metal-dependent proteases, putative molecular chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03068_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000379">
        <property type="protein sequence ID" value="SCN46928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TsaD" evidence="1">
        <location>
            <begin position="2"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="156" mass="16941" checksum="EF60364E330EF10E" modified="2016-11-30" version="1">MQGIAYGADLPVVPVSTLAAISQACLQKTTYDMIFTAVDARMSEIYWAVYQRDAEGFAQLIGVEKVQPASDVDALQLTGYGIGSGWQVYEQVLTQRLGAQLLGFDAGYLPRSSQVALLGAIGVQRQQAVPVEQAMPVYLRDKVAKTTAEREALRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN65</accession>
    <name>A0A1D3RN65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_03040_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000555">
        <property type="protein sequence ID" value="SCN47155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920245" evidence="5">
        <location>
            <begin position="23"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="52"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="275"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="680" mass="73928" checksum="87174D3272771D3E" modified="2016-11-30" version="1">MDNKFISYSAASLLALTSSAFAAEDEIKQEPIELEPISVVNTTPFGAAKSIDKTPANIQIMTAEDLAKAQSISVPDYMNQYMGSVTVNDAQNNPLQPDVQYRGFTVSPLLGLPQGLSIYLNGVRFNETFGDNVHWDLIPKGAIDTMSLQSGSNPTYGLNSLGGAIALKTKTGFTAPEHSLTVSGGSWGRHTEEISSGWNNGEFAYFLDLQHFQEDGWRDQSPSQAFNGLGTFSWRGEAGQLNLTLAGADTRLIGNGATPVELEAINRKAVFTYPDKTSNEFFLAALDGNLWINDDVELAGNVYYRSNHVTTLNGDSSEFGSCDTDPNLLCEEGSDEVVEDVNGDEVLAVDAVEGGTLNTSKTKQWSFGIALQTAFNQSIMGYDNQFVIGTSYDLGNAGYSADTELGALTEDRGVDGAGILVDESRVRLDTKTHSIGLFFSDVFNITEQLAVSVSGRYNHVEIDMQDRGGNPKLTGNHKFDRFNPAAGLTYAFMPEFNFYSGYSESSRVPTPMELSCADPDDPCKLPNAFIADPPLEQVVAKTWEAGFRGRFTNVLEGRVRWNVGYFNTVNHNDIIFQSTGGANSAGFFDNVGKTQRQGVELGLSAAFFDRWRMSLNYSFIDATFLTPYVSQSPSHPSADANGDIQVQAGDRIPGIANHVVKFATDVDILDSWTVGMNVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN68</accession>
    <name>A0A1D3RN68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conjugative transfer protein TrbC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01638_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000388">
        <property type="protein sequence ID" value="SCN46948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007039">
        <property type="entry name" value="TrbC/VirB2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04956">
        <property type="entry name" value="TrbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="9091" checksum="8F943279009B03E5" modified="2016-11-30" version="1">MGTNAEAATTTGMPWETPLNNLLNSLTGPVARVIGAISIVVFGFGLAFSEGGGLIRRAMWIVLGLTIAFNALSWSLTFFGFTGGLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC5</accession>
    <name>A0A1D3RNC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR domain protein, putative component of TonB system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03040_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000555">
        <property type="protein sequence ID" value="SCN47154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_transf_41" evidence="1">
        <location>
            <begin position="64"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="265" mass="29682" checksum="4D003E00907EDF60" modified="2016-11-30" version="1">MSWLGFFASTGVPGIDFLLTDSISVPEDQRHYFSEKFYYLPETRLCFTPPDSDLMPGLLPVKQNNYITFGCFQNLSKINNAVIKVWGEIFKALPMAKLILRNKQMSCLEEKANLLQRLSLAGVSREQIEIGGLLTRESYLATYSDIDIMLDTFPYPGGTTTCEALWMGVPTLTLSGNTLLGRQGASLLNCVGLQDWIAQDEEEYITKAIQHSANIALLSALRENLRTQILETALFDASRFAKQFEGAMFGMWEQTLSEESVDLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE2</accession>
    <name>A0A1D3RNE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HigA protein (Antitoxin to HigB)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_272289_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000569">
        <property type="protein sequence ID" value="SCN47183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013430">
        <property type="entry name" value="Toxin_antidote_HigA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36924">
        <property type="entry name" value="PTHR36924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02607">
        <property type="entry name" value="antidote_HigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="95" mass="10882" checksum="600BE83ECDFBCBE3" modified="2016-11-30" version="1">MNMYNPPHPGEFIREVYLEPLKVSYRAVALKLHVAPSTFNRLIQGKSNISSEMALRLSKTLGRSPESWLAMQSNYNLWQAKQHLNLDEVEKLAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF1</accession>
    <name>A0A1D3RNF1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="9" type="ORF">BAZMOX_48678_2</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000583">
        <property type="protein sequence ID" value="SCN47210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PRA-CH" evidence="8">
        <location>
            <begin position="31"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="129" mass="14721" checksum="2E8A03684D757689" modified="2016-11-30" version="1">MSGTWLDEIRWTDDGLVPVIAQQAGTGKVVMFAWMNRESLALTNECGYAVYWSRSRNKLWRKGEESGNRQKVLAISVDCDEDVILLSIEQEGGISCHTGRESCFYRTLERGVWQENSPVLKNPAEMYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ3</accession>
    <name>A0A1D3RNJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Transaldolase</fullName>
            <ecNumber evidence="5 8">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_11998_3</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 8">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="5 8"/>
    <dbReference type="EMBL" id="FMJP01000489">
        <property type="protein sequence ID" value="SCN47078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="PTHR10683:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="283" mass="31015" checksum="5C1E5E19410186FE" modified="2016-11-30" version="1">MPQYQAIVDDTLKGARETLGATASDKEVASLAFDRLAVSFGLKILEIVPGRVSTEVDARLSFDTDASIAKGRDLIEQYEAAGVSRERVLIKVAATWEGIQAAKVLEEEGIHTNLTLIFGKHQAIACAQNGITLISPFVGRILDWYKKDTGRDSYEPAEDPGVVSVTEIYNYYKKFDFKTEIMGASFRNIGEIIELAGCDLLTIAPALLSELQSTEGELVRKLDPVAAKAMDIEEINVDKATFDKMHAADRMATDKLAEGIKGFEKAIITLEEILSKRLAELEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ9</accession>
    <name>A0A1D3RNJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ORF">BAZMOX_01036_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000535">
        <property type="protein sequence ID" value="SCN47129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="12"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="135"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="240" mass="26377" checksum="743D1A775E2C5425" modified="2016-11-30" version="1">MTKLICQRIMLKLSGEALMSDKGGNIDSDIVKRLATEIKELCDVGVQVGLVMGGGNILRGSEQAAEGLNRVTADQMGMLATVINALAMQDSLEFLGQQVRVMSALKINQVCEDYIRRRAVRHLEKGRVVIFAAGTGNPFFTTDSAASLRAIEINAELMIKATKVKGIYSADPEKVPEAKFYSRLTYDEALDQRLNVMDTTALVLCRDNDLPMRVMNIFETGAVMRLMQGEEIGSLIERGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL0</accession>
    <name>A0A1D3RNL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_165345_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000605">
        <property type="protein sequence ID" value="SCN47234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920267" evidence="1">
        <location>
            <begin position="24"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="237" mass="26217" checksum="1868DD04B047E7C9" modified="2016-11-30" version="1">MKKSKLKLIPLLFLVLLSGQVHAKKGEAEAERRAELAIPVLEVKPPVAGFEWITDQVGFDYLKPCDTGIPYAAIVAHGANHMDSLTDNGKGEFVHERDMNIGYPRMAEFCVIIEVPKSGLSTTFTEDNEKEEWRTWWVTNGVEDENGIPVRDEDEEIQATINQLKLSKSALGGIPVYLVIGNDLGKFTSNIIYKLGNAGEIDVIDGFIYVNRDTGEFIIHGIDGSIWKSADNTPPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN8</accession>
    <name>A0A1D3RNN8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amino-acid N-acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_00271_2</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ArgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000628">
        <property type="protein sequence ID" value="SCN47264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04237">
        <property type="entry name" value="AAK_NAGS-ABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01105">
        <property type="entry name" value="N_acetyl_glu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033719">
        <property type="entry name" value="NAGS_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010167">
        <property type="entry name" value="NH2A_AcTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30602">
        <property type="entry name" value="PTHR30602"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000423">
        <property type="entry name" value="ArgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01890">
        <property type="entry name" value="N-Ac-Glu-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="9">
        <location>
            <begin position="291"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="438" mass="48662" checksum="4823C51391FA0484" modified="2016-11-30" version="1">MHNSSSFVNWFRGSSPYIHAHRNRTFVIYFGGEAILDASLNNLVHDFALLNSLGIRLVLIHGIRPQIDLRLKKQNLPSLFHEQLRITDAAALQCVKEAAGLARVEIESLLSLGVANSPMSGAKIRVISGNFVTAQPQGVINGIDLQYTGKVRHVDKTAIQQQLDLDHVVLISPVGYSPSGDLFNLSAEQLATDVAITLQAEKLILMTEQSCHSIESGQLIAQMTTAETQAFIDHEPRLKFSTKHALQSAIKGCKAGVNRVHILNRKEDGALLTELFSRDGIGTLISSTEFESIRPATLNDIPGILELITPLEQQGLLVARSEEHLEININDYIVIERDGLIIGCTALHKITNSHVGLIACMAIHPDYRKAARGNQLLERLLIKAKQSSLRQLFALSTQTMHWFKERGFQESHFNELPHALQENYDHLRNSKVLKKNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP6</accession>
    <name>A0A1D3RNP6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsf</name>
        <name evidence="7" type="ORF">BAZMOX_01036_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the EF-Ts family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000535">
        <property type="protein sequence ID" value="SCN47128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="6">
        <location>
            <begin position="72"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="81"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="291" mass="31365" checksum="B69D7DBD40BA7F07" modified="2016-11-30" version="1">MSVTAGMVKELRERTGSGMMECRRALIEADANMELAIENMRKAGLAKADKKSGRIAAEGRIAVAQSEDTKNAVIIDVNCETDFVAKGDVFKAFANDIAKAILASDVATPEEAYELTLADGKTIDEVRRGLISKLGENITLRRFQRVTTEGGTGFYLHGEKIGVLVSLEKADDELAKDVAMHIAASKPACVSEADVAPEVIEKEKAIFVAQAEESGKPANIIEKMIGGRIKKFLAEITLEGQAFIKDDKMTVGQLVKGKDNKVLAFTRLEVGEGIEKAEGDFASEVMAQIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP8</accession>
    <name>A0A1D3RNP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_79136_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000656">
        <property type="protein sequence ID" value="SCN47310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010522">
        <property type="entry name" value="RepC_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06504">
        <property type="entry name" value="RepC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="222" mass="24817" checksum="0F49A13630FBF81C" modified="2016-11-30" version="1">MDDIKYPAARSKRIIHAAPQFRPIKRGARKKGIERKYEAKNGDTLTIAIFHELDIADQDLLLCLLSIARAEDRGVCVGPVPTTDLGIHLRDELKLKGKAEKATALLVNATGYEILKELGRTDGSSNYKWLRGSLKRLSRVSFDYDCKKGFWSFKLLSVMGFYGEKGEIKDISVCINPLSAQAILGNDGGYVMVNRNERSILEKSKSSSESKALPLKIRETER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ3</accession>
    <name>A0A1D3RNQ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH araC/xylS-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_114231_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000680">
        <property type="protein sequence ID" value="SCN47345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="71" mass="8025" checksum="D53EC1C2A494CADB" modified="2016-11-30" version="1">MWQRLKYAISIFGSTHSLTYAGLEAGFNDASHFSRCFKARYGVSPSVIHNVLEMYEVSGDERKKGFCRICG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ8</accession>
    <name>A0A1D3RNQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_221043_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000663">
        <property type="protein sequence ID" value="SCN47320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003173">
        <property type="entry name" value="PC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009044">
        <property type="entry name" value="ssDNA-bd_transcriptional_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02229">
        <property type="entry name" value="PC4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54447">
        <property type="entry name" value="SSF54447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PC4" evidence="1">
        <location>
            <begin position="47"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="PC4" evidence="1">
        <location>
            <begin position="132"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="245" mass="28207" checksum="B2546697277A6499" modified="2016-11-30" version="1">MSRKSKAKDQTKALNIPFTLTQADLVQEALAVAKDQTQALNIPVKVPLGGGRYAELTEWNASKRVDLRFWKTDTIPTKVGVSLSLPQWKILCSATQVVDDLISREKDGESVDWRYDLGEDVYVIIKAPQLTIHIRKYFVPNGECTLHPTKRGVTLSLYEWKELKKTIPLFEDREPELLHRHHHRRRRCTTTKKKGGENRACAEQTSGQGHFRSRDFVTSGQTAPLGRLSRNFRLRMRRTYFRTCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ9</accession>
    <name>A0A1D3RNQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GGDEF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00412_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="136" mass="15481" checksum="89BC387D0CA5BB5F" modified="2016-11-30" version="1">MTAKIDNLAIISNNTFEATKASNLNHYDISSALQTTLEFHELVHIFSTKIQELVPHNGFIYTNTEFDLNIQKGIQTKNTCSYALKVEDQDLGELTLMRHTRFSKHEIDLLETLLCCLIYPLRNATLFNGALKTGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR5</accession>
    <name>A0A1D3RNR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02254_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000572">
        <property type="protein sequence ID" value="SCN47189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="20"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="292" mass="32562" checksum="443C94DCAF940CA2" modified="2016-11-30" version="1">MVDANVTLTAESLVQGSITLFSLPDIYHQIEKMVNDPRFTALEIGQVIAKDPALSMRLLKLVNSSFYGFQSRIDTISRAVTIIGIKDLQSLVLATSVVDVFNDIPSDLVDMTDFWLQSVQCGVVAKLLAKESSVLHAERLFLAGLLHKIGTLVLYQKLPELSSKVLKLADYNAELVPVIEQEMIGFTFADVGGELAKSWALPDSLHEAIAYQLTPEVALAHRLDAQILHIATIFCTALVYDQDLVSELWDAIPFERKSLISLDQKQFFTLLLQAQEDVRQFFELLASGKKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS1</accession>
    <name>A0A1D3RNS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative stomatin/prohibitin-family membrane protease subunit YbbK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_117817_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000691">
        <property type="protein sequence ID" value="SCN47365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="281" mass="30637" checksum="0704498BCE41C3A4" modified="2016-11-30" version="1">MEGLYIVGAFVVLVIVTVIKGVRIVPQGYKHIVQRLGKYHQTLNPGLNFVIPYVDSVIEKITTKDIVLDIPSQEVITKDNAVIVANAIAYINIVSPEKAVYGVEHFVMAIEKLIQTSLRAIIGEMSLDEALSSRDHIKTKLKESISDDIADWGITLKTVEIQDINPSQTMQASMEEQGAAERERRAAVTRAEGAKQAAILEADGRLEASRRDAQAKILLAQGSAKAIESVAEALQGKDLPVTYLLGEKYIEAIRDLSESDNAKTVVIPADLIHAVKGMLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-06-17" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY1</accession>
    <name>A0A1D3RNY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04812_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000707">
        <property type="protein sequence ID" value="SCN47383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4056" checksum="390334D620AC4DE7" modified="2016-11-30" version="1">MSIGVTALQAADDVESFVARADKALYAAKTGGRNKVMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY3</accession>
    <name>A0A1D3RNY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Superoxide dismutase [Mn]</fullName>
            <ecNumber evidence="2">1.15.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_77164_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.15.1.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000719">
        <property type="protein sequence ID" value="SCN47400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5703" checksum="3337976894AF0EBB" modified="2016-11-30" version="1">MFGIDVWEHAYYLQYKNVRPDYVNAIWNIVNWKNVEQRLQDAKMEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP05</accession>
    <name>A0A1D3RP05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_53206_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000596">
        <property type="protein sequence ID" value="SCN47228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="92" mass="10415" checksum="62A1F2D409A4C354" modified="2016-11-30" version="1">MKWTIPEKTDLVLYFGRCLGSLGLVLEYCTYQAATIGAGEEVVFQFWIGICLFMVGLHIYGAIKRIQPITETLEIALWVLLLLLSLAFYPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP25</accession>
    <name>A0A1D3RP25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_103020_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000750">
        <property type="protein sequence ID" value="SCN47433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920275" evidence="1">
        <location>
            <begin position="21"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="288" mass="33938" checksum="ABB5BC4EBDC29ABE" modified="2016-11-30" version="1">MKKILLVLLAGIFTWNPAIASLNSKLTLKQDLDASSRSYLDMKKKADEAAKRDLLEATYEKLRPGSVEVRDRVQRFYWDVDRIRYSAQLTFEKSGVRGELPNRRLFLVAHYTEEKYLILTKETQTQVSRTKTNSRTPVTLTGALQRASQVLSWWKLAVRISKSIHGEIHRREDKFGTNIYRKDVDGTLAYARREKKWAEEEYDRISDRLEYYSAESIERRRTAAHEAAEISFEERNRMIMERYESAERAFSKIESKGFMDVNMLFQEYLNIQKIKGIFPTLKIRETER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP42</accession>
    <name>A0A1D3RP42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_49079_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.13" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000796">
        <property type="protein sequence ID" value="SCN47505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hcy-binding" evidence="3">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="47" mass="5252" checksum="8237380D639C71C2" modified="2016-11-30" version="1">MRQYEGLVDGGTDILLIETVFDTLNAKAASFCYRSSFLSSIILNYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP44</accession>
    <name>A0A1D3RP44_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetylornithine aminotransferase</fullName>
            <shortName evidence="2">ACOAT</shortName>
            <ecNumber evidence="2">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argD</name>
        <name evidence="4" type="ORF">BAZMOX_00271_6</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:18049"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.6.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000628">
        <property type="protein sequence ID" value="SCN47268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="91"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="210"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="386" mass="41579" checksum="1EC570D0F1695F04" modified="2016-11-30" version="1">MPTYGRLPVTFTKGEGAWLWDENNKRYLDALSGIAVCNLGHAHPAIHEALCKQSKTLLHTSNLYNIEVQEQLATKLCQLSGMDNVFFGNSGAEANEAAIKIARLYGHNKNITNPVVLVMQKSFHGRTMGTLSATGNPIIQDGFSPLLEGFVHVSYNDTHAIEIAIQQNPNIVAVLVEPIQGEGGVNIPAPDYLTQIRKLCDQHDLLMMLDEVQTGIGRTGAWFAFQHNNITPDVCTLAKALGNGVPIGACMAKGKAATLLTAGKHGSTFGGNPLVCSVALAVLNTIENENLCQQAADKGDAIQQAFTEQLKNNKHVLEVRNKGMMIGIQLDAPCTELVAIALAEGLLINVTGATTIRLLPPLIINKEQIELLVSKLSVLVNCHTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP58</accession>
    <name>A0A1D3RP58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BAZMOX_03955_1</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="FMJP01000670">
        <property type="protein sequence ID" value="SCN47329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02042">
        <property type="entry name" value="DusB_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032887">
        <property type="entry name" value="DusB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="12">
        <location>
            <begin position="29"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="352" mass="38515" checksum="D78BA8E09D28273E" modified="2016-11-30" version="1">MTLILQIPVDNEKLQKMQIGPYQLENNLILAPMAGITDRPFRNLCKQYGAGLAVSEMVASNPALRKNKRTLLKADHSGEVGLRSVQILGTDPKQMAEAAQINAQRGAHIIDINMGCPAKKVCSVAAGSALMRNEDLVKRILEAVVQAVSIPVTLKIRTGWDSDNRNAVNIAQIAQQSGIAALTIHGRTRACAFKGDAEYDTIKAVKQTVSIPVIANGDINSVEKAQYVLEHTGADAIMIGRGAQGRPWFFQEIQHYLQTGKHASPANLEQIKITLQQHLAELYLFYGTLNGVRIARKHIGWYFSYIGTLPPAIKSKIYQADAPEVQLSLVNSAFDLFDPPISLQPTNNACKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP74</accession>
    <name>A0A1D3RP74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_396885_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000739">
        <property type="protein sequence ID" value="SCN47422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="115" mass="13232" checksum="2F414DBCF0A58126" modified="2016-11-30" version="1">MEGMFTINDKSMNMQRIDETVRLGDTEIWAITNEADMAHPFHIHDIQFQILDRNGQAPVAGEAGWKDTVLVLPNETVRVITRFEDFADKDIPYMYHCHILEHEDAGMMGQFVVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP79</accession>
    <name>A0A1D3RP79_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BAZMOX_05066_0</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000684">
        <property type="protein sequence ID" value="SCN47349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038438">
        <property type="entry name" value="PepN_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012779">
        <property type="entry name" value="Peptidase_M1_pepN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024601">
        <property type="entry name" value="Peptidase_M1_pepN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037144">
        <property type="entry name" value="Peptidase_M1_pepN_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035414">
        <property type="entry name" value="Peptidase_M1_pepN_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322">
        <property type="entry name" value="PTHR46322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11940">
        <property type="entry name" value="DUF3458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17432">
        <property type="entry name" value="DUF3458_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02414">
        <property type="entry name" value="pepN_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M1_N" evidence="14">
        <location>
            <begin position="70"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="11">
        <location>
            <begin position="234"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3458" evidence="12">
        <location>
            <begin position="452"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3458_C" evidence="13">
        <location>
            <begin position="558"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN47349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="879" mass="99555" checksum="EA627D1F9206ECF7" modified="2016-11-30" version="1">MTDTKPQTIYLKDYLVPEYLIQTVDLNFILDAEHTRVVSRLTLNSNPDSQVKHAPLELLGEDLNLVSIVLDGVALTESQYQLTDEALTIQHVPQDQSFTLEIENSINPKANSALEGLYISNEMLCTQCEAQGFRKITYFLDRPDVMSRFTTTLVADKTLYPVLLSNGNKVAQGELTENRHWVTWEDPFKKSCYLFALVAGQLECIEDHFTTMSGRDITLKIFVEAHDIDKCSHAMQSLKNSMRWDEETYGREYDLDLYMIVAVGHFNMGAMENKGLNIFNTKFVLARPDTATDMDYEHIEGVIGHEYFHNWSGNRITCRDWFQLSLKEGFTVFRDQEFTADQTSRAVKRIDDVIALRTRQFAEDTGPLAHPIRPEAYIEINNFYTLTVYEKGAEVVRMIQTLLGAENFRKGSDLYFQRHDGQAVTCEHFVQAMEDASGKDLSQFRRWYAQAGTPVLSVEANYHAEQQSLALTLNQSIPTQSNAAILHIPVKVALFAGDGSVMTLNIAGCQETDNEVTLELTKASQTFIFEKVASAPHISVLREFSAPVKLKMERSLTELAFLLQHDNDSFNRWEAGQQLSTAIIFGLIDALKQGQTLILPEILCTSFKTVLEQAWTDLSYLACLLSLPSVNYLAEQMAVVDVLAIHQARDFVKRSLAEQLNEQFSALYQENHKEESGQLSAKAIGHRRIKNICLDYLSQLETEKSYQLVNKQFTSAKNMTDQIAALGALVDSQNPEKSASLESFYQQWESEGLVIDKWFSLQAMSTQADTFSVVQRLLQHAAFDLKNPNRVRALIGAFSQSNPLHFHAENGQGYQFLADQVIALNKINPQVASRMVGALTQWRRFDKARQTLIKQQLERIINTEHISKDVFEIASKSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP89</accession>
    <name>A0A1D3RP89_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ORF">BAZMOX_26533_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000801">
        <property type="protein sequence ID" value="SCN47520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="PTHR46986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="157" mass="17863" checksum="D702652E4297C9CB" modified="2016-11-30" version="1">MLARWLDIQRIVDLDSLPSDDDLQLWVETALADYNQDAEILIRIIDTQEMIELNSRYRGKHGATNILSFPFELPDGVEAIDLLGDLVVCAAVLEQEAEQQNKALSAHWAHIIIHGVLHLLGYDHLTNDEAIEMESKEIILLQELHIDNPYQEKEVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA3</accession>
    <name>A0A1D3RPA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-hexulose-6-phosphate synthase</fullName>
            <ecNumber evidence="4">4.1.2.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_41472_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-ribulose 5-phosphate + formaldehyde = D-arabino-hex-3-ulose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:25201"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58542"/>
            <dbReference type="EC" id="4.1.2.43"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; formaldehyde assimilation via RuMP pathway; D-fructose 6-phosphate from D-ribulose 5-phosphate and formaldehyde: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HPS/KGPDC family. HPS subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.43" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000778">
        <property type="protein sequence ID" value="SCN47476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00294">
        <property type="reaction ID" value="UER00434"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043801">
        <property type="term" value="F:hexulose-6-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019647">
        <property type="term" value="P:formaldehyde assimilation via ribulose monophosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04726">
        <property type="entry name" value="KGPDC_HPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017553">
        <property type="entry name" value="3-hexulose-6-phosphate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041710">
        <property type="entry name" value="HPS/KGPDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03128">
        <property type="entry name" value="RuMP_HxlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="7">
        <location>
            <begin position="5"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="213" mass="21782" checksum="EC37070C36FAB180" modified="2016-11-30" version="1">MATPLIQMALDSLDFDATVALAEQVADSIDIFEIGTPCIKHNGINLVKELRARFPNKLLLVDLKTMDAGEYEATPFYAAGADICTVLGVSGLATCKGVIAAANAHGAEAQIDLINVDDKAACARATVEAGAQIVGVHTGLDAQAAGDTPFNDLALIADLGLNVRVSVAGGINQSTVQDVVRAGADIIVVGAAIYGAASPAEAAREIRELVDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA5</accession>
    <name>A0A1D3RPA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_148500_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000830">
        <property type="protein sequence ID" value="SCN47565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4386" checksum="699C645FB160DE63" modified="2016-11-30" version="1">MSGVKRFKSHHRFGCFFGSGLNMLLSMNIWFLGAPPRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA6</accession>
    <name>A0A1D3RPA6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apt</name>
        <name evidence="12" type="ORF">BAZMOX_00594_2</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="46"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="171" mass="18961" checksum="18869B9E540E1729" modified="2016-11-30" version="1">MLRLKDKIRDIPDFPKLGITFKDITPLVKDPAALRLSVHQLIQPFLGRNITAVAGMEARGFIFGSLVAWELNLPFIPLRKPGKLPYDAQSVSYDLEYGSASLEIHTDALDKNDHVLLIDDLLATGGTAKASCELIEQLSASVTALAFVIELDFLKGREQLSTYEVHSLLHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC2</accession>
    <name>A0A1D3RPC2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Catalase-peroxidase</fullName>
            <ecNumber evidence="4">1.11.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_46310_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>AH2 + H2O2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000840">
        <property type="protein sequence ID" value="SCN47585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="PTHR30555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="SSF48113"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00198">
        <property type="entry name" value="cat_per_HPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEROXIDASE_4" evidence="5">
        <location>
            <begin position="15"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="532" mass="57721" checksum="BE1566EFB9185DE5" modified="2016-11-30" version="1">MGLIYVNPEGPDGNPDPLLAAADIRITFGRMAMNDEETVALIAGGHTFGKAHGAHNPKECVGAEPAAAGLEEQGLGWKNKCGTGMGADTVSSGLEGAWTISPTAWSINYLQNLISLEWVKTKSPAGATQWTPKNAHEVKFVPDAHIPGKTHAPIMFTTDIALKADPKYREIVERFLGNSEEFDLAFAKAWFKLTHRDMGPQTHLLGPDVPEAQLWQDPIPVADYPLVDAKDIKKLKASILDSGLTVPQLVRTAWGAAASFRGTDFRGGANGARIRLAPQKDWPVNSPAELAKVLNIFESIQKKFNDDAESTGSWFGFGKDDTTKKQVSLADLIVLGGAAAIEKAAQDAGYDVNVPFTPGRVDTTQELTDVDSFAVLEPTADGFRNYFDQKNTQSPAEMLVERANLLNLTVPEMTVLVGGMRALNANVEGNSHGVLTKQPGTLSNDFFVNLLDMSTKWEKSTKDQGVYLGLDRKSGNVKWTASPVDLVFGSNNELRAVAEVYASDDAKQKFVNDFIAAWVKVMTLDRFDMAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD6</accession>
    <name>A0A1D3RPD6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4351 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_168962_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000784">
        <property type="protein sequence ID" value="SCN47482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025587">
        <property type="entry name" value="DUF4351"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14261">
        <property type="entry name" value="DUF4351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4351" evidence="1">
        <location>
            <begin position="55"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="120" mass="13831" checksum="B14DD1699128FEB8" modified="2016-11-30" version="1">MQIKYADFIDAYAALSEEEMQQYQKSYVATDEVIMGLAQILRQEGLDQGIEQGLKQGRQQECINLISRLLRRKLGIHPEVEIILETLTNLSLETLESMTDVLLDFNEVADLKEWISQQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG0</accession>
    <name>A0A1D3RPG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_17197_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000747">
        <property type="protein sequence ID" value="SCN47429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="4"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="276" mass="30822" checksum="3368E23CED10573B" modified="2016-11-30" version="1">MRHGIYPGAPKYPFTPGYDIAGYIEKTGESVKEFKPGERVVALTQFGGYAQYVCVDKNIPIKIPDKMDLDAAVSLVLNYITAFQMIHSTARLKKGNTVLIHSAAGGVGTALLQLGKVMGLKIYGTASVMKHTIVEKYGFAIDYKNEDFVQRIKELEPEGLDAVFDPIGGDNWERSLKTLKKDGQLIGFGGLSMFNRDRLISNHLTVISTKENFIFYRVPVNNHEQLKENYTKLLKLYEEKLIDPIVGKILALEEVRTAHKLLSEGRIIGKIILNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH8</accession>
    <name>A0A1D3RPH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_04184_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000731">
        <property type="protein sequence ID" value="SCN47408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02125">
        <property type="entry name" value="L3_methyltr_PrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017127">
        <property type="entry name" value="Ribosome_L3_Gln-N5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037167">
        <property type="entry name" value="Mtase_YfcB_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03533">
        <property type="entry name" value="L3_gln_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="4">
        <location>
            <begin position="132"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="310" mass="34228" checksum="68B54E693CDF9A95" modified="2016-11-30" version="1">MQPTSAATIQTLMTVRDYIRWAASRFSEAKLFHGHGTATALDDAAALILHSLSLPYNLSESYFSARLTHTEREKIIDLVNRRVSSRVPSAYLMHEAIFAGLPFYVDERVLVPRSPIAELIQEQFSPWVDADSIGHVLDLCTGSACIAIACAYAFPDALVDAVDLSEDALDVAKINLAKHGLAEQLTLYHSDLFSALPVQKYDLIVSNPPYVAIAEWEQLPAEFHAEPEMGFTGGESGLDLVIKILVDAADYLSEQGILVIEVGSSAETLQEKFPDIPFYWLNFENGGDGVFLLTAEQVFVFNEQFKAVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI2</accession>
    <name>A0A1D3RPI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03845_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000890">
        <property type="protein sequence ID" value="SCN47645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5005" checksum="31A69455EDC5DAC7" modified="2016-11-30" version="1">MLAIERQSSTKEAPSKSLAYLVDTVNSTGAANYNNFVLNLYKPNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI5</accession>
    <name>A0A1D3RPI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA 5-methylaminomethyl-2-thiouridine synthase TusD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_336538_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DsrE/TusD family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000867">
        <property type="protein sequence ID" value="SCN47610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017463">
        <property type="entry name" value="Sulphur_relay_TusD/DsrE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03012">
        <property type="entry name" value="sulf_tusD_dsrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="129" mass="14568" checksum="EC2C07100875BDD5" modified="2016-11-30" version="1">MKYAIQVNSSPHQANSADTAYQFIKAALEMGHEVVRVFFYQEGIYHALRYATPPSDEVQVVTRWTKLAEDYDLDLVVCISAAQRRGLLEPGEAKRQGKQDNDIAEGFRIAGLGLWVEAMLIADRFIEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL7</accession>
    <name>A0A1D3RPL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_113592_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000841">
        <property type="protein sequence ID" value="SCN47586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="59" mass="6912" checksum="43127852549E6276" modified="2016-11-30" version="1">MTPYEKLKSLDQSEDYLKDALSFELLDKEAYKVSDNQAADQMNLAKKRLFKQINEQKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL8</accession>
    <name>A0A1D3RPL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_05330_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000832">
        <property type="protein sequence ID" value="SCN47572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920276" evidence="1">
        <location>
            <begin position="24"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="76" mass="8303" checksum="2E890AD26D6D9955" modified="2016-11-30" version="1">MKTSLIIGIFTAALTVIPNISSANSDDNRYPAANFQPKVIYIDKEAAKAPAKIFAEKSVFDPKYPAANFVPKVIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM7</accession>
    <name>A0A1D3RPM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon storage regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_129026_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000853">
        <property type="protein sequence ID" value="SCN47596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003751">
        <property type="entry name" value="CsrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036107">
        <property type="entry name" value="CsrA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34984">
        <property type="entry name" value="PTHR34984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02599">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117130">
        <property type="entry name" value="SSF117130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00202">
        <property type="entry name" value="csrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="63" mass="6672" checksum="D08A6B7DB49FA94E" modified="2016-11-30" version="1">MIGDDVTVTVLGVKGNQVRIGINAPKDVSVHREEIYERIKNEKAGNSDSVVESGSAGLMGSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ0</accession>
    <name>A0A1D3RPQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_241654_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000733">
        <property type="protein sequence ID" value="SCN47417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="56" mass="6842" checksum="040FA3EA5B05BB20" modified="2016-11-30" version="1">MISFKRTHFPKDVILYAVFFYVRYGVSYRDLEEIMEERGVNVDHATLNRWGFCRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ8</accession>
    <name>A0A1D3RPQ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 4">2.7.7.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">UDP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_02872_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 4"/>
    <dbReference type="EMBL" id="FMJP01000872">
        <property type="protein sequence ID" value="SCN47612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01099">
        <property type="entry name" value="galU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="5">
        <location>
            <begin position="12"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="296" mass="32562" checksum="B972D3BD4798F084" modified="2016-11-30" version="1">MTQKITKAVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVEEAVAAGIDTMIFVTGRNKRAIPDHFDKSYELEKELEAKNKLRVLDMVRNILPSHVSCIFIRQSEALGLGHAVLCAKPIVGDEPFAVILADDLVEDGKRGCIAQMTQQFTKTPHSLLAVERVDPNETDKYGIVKTTSTDNDKIGEVQSIVEKPKPDVAPTNLGVIGRYILTPAIFAEIESTGRGAGNEIQLTDAIASLLAKEKVLAYEFEGKRYDCGAKLGFLMATVEQALLHEELKDDFLDYLKTLAKKYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR2</accession>
    <name>A0A1D3RPR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Probable methyl-accepting chemotaxis protein IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_03845_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000890">
        <property type="protein sequence ID" value="SCN47644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025991">
        <property type="entry name" value="Chemoreceptor_zinc-bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13682">
        <property type="entry name" value="CZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="3">
        <location>
            <begin position="196"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="492" mass="54861" checksum="5C84A1997AD6C569" modified="2016-11-30" version="1">MSAHNKSSANIPFLKAKITYAISAIIFLSAFVFSVNFYLYGLSWLTLLSCIALIIIAFFILRSVNATLKVLNTIQEILLKTNQGELYHRITNTRGLGEIGKVAWELNEMLDIMESYFKEVNASFSHASKGNHDRYVLADGFPGLLKQSATNINNALHLMAENELLMTKNKLSANLHTLNTSNLLDNLKVNQQDLINITDQMQKVENIATDTGRNADASLSTVDDISHSLTDINETIHEVSDVINALIEDSRKVTDSLSMITGIADQTNLLALNASIEAARAGEHGRGFAVVAEEVKNLSEHTKNAALEVTKTLDSFNKRVSQMNTKANSSTELSQNIMEQVVSFKGQFASLSSSAKESIAYISYSKDKSFGLLTKLDHIIYKQNGYLAIEEESNCPQADAINVDNHHCRLGKWYYEGLGRDKFRHTNAYAKLSVPHQEVHTFTQQAYAFSRQNWQDNPEILNNIVSGMEKSESASANVMQLIDQMIEEKHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR3</accession>
    <name>A0A1D3RPR3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">glmU</name>
        <name evidence="17" type="ORF">BAZMOX_15857_0</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="FMJP01000922">
        <property type="protein sequence ID" value="SCN47681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="16">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="8"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="15">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="249"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="15">
        <location>
            <begin position="385"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SCN47681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="456" mass="49354" checksum="5DAF5A9FF360B6F8" modified="2016-11-30" version="1">MTLKTLILAAGQGTRMRSARPKVLHEIANRSLLQHVYDTSKLLDGNEIIVIYGHGGELVKQSLSNLDAQWVEQKEQLGTGHAVLQADNLINNDDTVLILYGDVPLLTKHSIEQLLGNVTKQSLALLTVNLDDPTGYGRIVRDNEGKVTKITEHKDATEQERLIKEVNTGILAVKGEKLKSWIARIGNSNAQQEFYLTDVIEMAVNEGITIKTSQPEHPDEVLGVNNRKQLSHLERVYQLAQADKLMKVGVTVVDPARIDCRGTFASLGQDISVDINVIFEGKNSIGNNVSIGANTIINNSVIADDVQILANCIIDNAVVGTGSKVGPFARLRPLAELAEHVHIGNFVEIKKSTVAKGSKINHLSYIGDATIGSGVNIGAGTITCNYDGVNKFRTVIEDGAFIGSDTQLIAPVTVGKNATIGAGSTITKDTPDEQLSLSRAKQISIQGWQRPVKKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR6</accession>
    <name>A0A1D3RPR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_29650_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000885">
        <property type="protein sequence ID" value="SCN47636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4900" checksum="9B99BC85277788ED" modified="2016-11-30" version="1">MFPAEITNNRWIPPFKPDENWSISADHDEGCPPSRSGADVTANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR8</accession>
    <name>A0A1D3RPR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_196227_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000928">
        <property type="protein sequence ID" value="SCN47693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018841">
        <property type="entry name" value="DUF2442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036782">
        <property type="entry name" value="NE0471-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10387">
        <property type="entry name" value="DUF2442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143880">
        <property type="entry name" value="SSF143880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="80" mass="9395" checksum="2486353AA3D7E129" modified="2016-11-30" version="1">MNPNVIDVEVKQKYILKLAFENKEVRIFDASPFLDKGIFRELKNINYFKQVKVAFGAIEWPHEQDFSKDTLYLLSTPLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV5</accession>
    <name>A0A1D3RPV5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ADP-L-glycero-D-manno-heptose-6-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">ADP-L-glycero-beta-D-manno-heptose-6-epimerase</fullName>
            <shortName evidence="3">ADP-glyceromanno-heptose 6-epimerase</shortName>
            <shortName evidence="3">ADP-hep 6-epimerase</shortName>
            <shortName evidence="3">AGME</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hldD</name>
        <name evidence="5" type="ORF">BAZMOX_45097_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ADP-D-glycero-beta-D-manno-heptose = ADP-L-glycero-beta-D-manno-heptose</text>
            <dbReference type="Rhea" id="RHEA:17577"/>
            <dbReference type="ChEBI" id="CHEBI:59967"/>
            <dbReference type="ChEBI" id="CHEBI:61506"/>
            <dbReference type="EC" id="5.1.3.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
        <text evidence="3">Binds 1 NADP(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; ADP-L-glycero-beta-D-manno-heptose biosynthesis; ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homopentamer.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.20" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000948">
        <property type="protein sequence ID" value="SCN47730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00356">
        <property type="reaction ID" value="UER00440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008712">
        <property type="term" value="F:ADP-glyceromanno-heptose 6-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097171">
        <property type="term" value="P:ADP-L-glycero-beta-D-manno-heptose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05248">
        <property type="entry name" value="ADP_GME_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01601">
        <property type="entry name" value="Heptose_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011912">
        <property type="entry name" value="Heptose_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02197">
        <property type="entry name" value="heptose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="201"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="10"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="31"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="76"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="314" mass="35392" checksum="3D6FAF547745F61C" modified="2016-11-30" version="1">MIIVTGGAGFIGSNIVKTLNQQGRTDIIVVDDLTDGKKFRNIADCDIADYWDKDDFLNRVQKDADLPPNIEVIFHEGACSSTTEWDGKFMMQNNYEFSKILLHFCLTHSIAFIYASSAATYGGGKQFTESREYESPLNVYGYSKWQFDQYVRSLKLGSQSQVVGLRYFNVYGPREQHKGSMASVAFHLHNQLLKGENPKLFSGCDGYEDGGQLRDFIYIDDIVAVNLWLFAHPEVQGIFNVGTGKAQSFKDVANAVIDFHKKGEIEYIPFPDHLKGSYQSFTEADMRKLRAAGYDAPFKTVQEGVALYLESLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX1</accession>
    <name>A0A1D3RPX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BAZMOX_03760_2</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000816">
        <property type="protein sequence ID" value="SCN47548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015956">
        <property type="entry name" value="Peniciliin-bd_prot_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012907">
        <property type="entry name" value="Peptidase_S11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037167">
        <property type="entry name" value="Peptidase_S11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07943">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00936">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69189">
        <property type="entry name" value="SSF69189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 16" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBP5_C" evidence="15">
        <location>
            <begin position="284"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="12">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SCN47548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="392" mass="44174" checksum="3DE564DDA6D7EBE9" modified="2016-11-30" version="1">MFLKIPINYPFALKIALLAFFCLPFTQINAETEILIPAPPRLAASSYILLDADSQRVLAEKNADEVLPPASLTKIMTVYIAFRELKNNRLSLDEMVTVSEKAWRTPGSKMFIEVNKQVKVEDLLKGIVIQSGNDASVAIAEHIAGDERTFAEMMNQQARRLGMSSTHFANSTGLPAPNEHYTTARDLALLTRALIREFPEYYRWDKEKEFTFNNITQKNRNTLLWRDESVDGVKTGHTEAAGYCLVASAKREDMRLISVVLGTKSKSARANESQTLLNYGFRFFETHKLYDANTILTTARVWKGASEVVNLGLADDMYVTISRRHYKEMKATTHVDLKLLAPIKVGDNLGTVNVMLRDKIITSQPLIALNAIEKGSFFQRAYDSALMLIKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY5</accession>
    <name>A0A1D3RPY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BAZMOX_02140_1</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="15">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000854">
        <property type="protein sequence ID" value="SCN47599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00290">
        <property type="entry name" value="cytochrome_b_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00284">
        <property type="entry name" value="Cytochrome_b_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030689">
        <property type="entry name" value="Cytochrome_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038885">
        <property type="entry name" value="COB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="SSF81648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="12 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="8 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="17">
        <location>
            <begin position="8"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_CTER" evidence="18">
        <location>
            <begin position="230"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="SCN47599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="464" mass="52938" checksum="122E32818CFF9CE6" modified="2016-11-30" version="1">MKTHLENCGNWFLDRFPLTKLWNDHMAQYYAPKNFNFWYFFGSLALLVLVNQFVTGILLTMNYKPDAGLAFDSVEYIMREVPWGWLVRYMHSTGASAFFLVVYLHMFRGLIYGSFKQPRELIWIFGMLLFVALMAEAFMGYLLPWGQMSYWGAQVIISLFSAIPVIGDDLSLWVRGDYVISDATLNRFFAFHVIAIPIILIMLVFLHIVALHEVGSNNPDGIEIKASKDPWGHPVDGIPFHPYYTVKDIVGVSVFIFFFATVLFYMPEMGGYFLEHANFIPADPLATPEHIAPVWYFTPFYAILRAIPDKFAGVIAMGGAIVVLFLLPWLDRSPVKSIRYRGGIYKKALLMFVISFLGLGYLGMQAPTAGATIMARIFTAMYFGFFLLMPIYTRWEKTKPVPKQLTEQPTIEDRIPGWKATFCEMVKEVPVEKDGTTVMRKRPDTSGIINVLIRTAKNLKASLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ9</accession>
    <name>A0A1D3RPZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphogluconate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_13384_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.12" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000985">
        <property type="protein sequence ID" value="SCN47771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004456">
        <property type="term" value="F:phosphogluconate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009255">
        <property type="term" value="P:Entner-Doudoroff pathway through 6-phosphogluconate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004786">
        <property type="entry name" value="6-phosphgluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43661:SF1">
        <property type="entry name" value="PTHR43661:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="231" mass="24541" checksum="D2F9E0133B1AC186" modified="2016-11-30" version="1">MHSVVEKVTQRIIERSHVVRSLYLKHIDKAAEDGPHRSTLACGNLAHGFAACSTGEKADLTENKKANIAIISSYNDMLSAHEPYKDSPALIKAAIREAGGVAQFAGGVPAMCDGVTQGQPGMELSLFSRDVIAMSTAISLSHNMFDGGLYLGACDKIVPGLLLGALSFGHLPAVFVPSGPMTSGITNKEKAMTRQLYAEGKIGRKELLESESKSYHSPGTCTFYGTAIATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ01</accession>
    <name>A0A1D3RQ01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_30428_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001017">
        <property type="protein sequence ID" value="SCN47825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="47"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="122" mass="13585" checksum="5AFF44E38968B726" modified="2016-11-30" version="1">MNDHPLCGRCKKPLFTQHPIELTATTFARHISRNDIPILVDFWAPWCGPCKMMAPAFAQAAEQLEPQVRLAKVNTEIEQALAGQYNIRSIPTLALFKNGKEVARQAGAMAKADIIRWVNANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ07</accession>
    <name>A0A1D3RQ07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_111148_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000800">
        <property type="protein sequence ID" value="SCN47517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4660" checksum="82E56E675495CD01" modified="2016-11-30" version="1">MLAGGADHKRLENKSVKKYKLHFFIMGNSMTNLLSLYCTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ24</accession>
    <name>A0A1D3RQ24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_387374_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000960">
        <property type="protein sequence ID" value="SCN47746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041527">
        <property type="entry name" value="YhcG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17761">
        <property type="entry name" value="DUF1016_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1016_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="73" mass="8158" checksum="62DBD84B9017A286" modified="2016-11-30" version="1">MNQPLSNTDLFIEVKGLIQSAKQQAAVAVNAELTLLYWQVGKRIADEVLKGERAEYGQPVIKTLAKQLTESDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ42</accession>
    <name>A0A1D3RQ42_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoA</name>
        <name evidence="13" type="ORF">BAZMOX_00676_4</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="23"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="250"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="335" mass="36639" checksum="28C60766EA00938F" modified="2016-11-30" version="1">MHSAVTGLLKPQLVEVVSKSLNHSRIVIEPLERGFGHSLGNALRRVLLSSIPGCAVVSVEIDNVEHEYSVIDGVHEDVIDILLNLKQLAVVLHSGNEVTLSLSKSGSGPITAADIQLPHDVEVINPDLVIANLTEEGALSMKINIQRGRGYEPSNTRTEGLGVGVVGALQVDASYTPINKVAYKVESTRVEQRTNLDKLIIELETNGTVDPESTIKLAATILHDQLSVFVDFEKVNDPIDEPVVEPVEHIDPTLLRPVDDLELTVRSANCLKAENIYYIGDLIQRTEFELLKTPNLGRKSLTEIKDVLALKGLSLGMRLENWPPENLAEQSQAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ79</accession>
    <name>A0A1D3RQ79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_451172_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001037">
        <property type="protein sequence ID" value="SCN47853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="7171" checksum="A9C59974772773DF" modified="2016-11-30" version="1">MISFKGTHFPKDVILYAVFFYVRYGVSYRDLEEIMEVGAPSYLMKYLGLLSPNIHSHTVRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ86</accession>
    <name>A0A1D3RQ86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02029_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001039">
        <property type="protein sequence ID" value="SCN47860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4634" checksum="8F244758B31D092D" modified="2016-11-30" version="1">MALIPLISLSKLGMQFAFIKTRLQLGYNNNQAIFFQRKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB5</accession>
    <name>A0A1D3RQB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GATase_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11216_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001032">
        <property type="protein sequence ID" value="SCN47844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase_3" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="100" mass="11476" checksum="A8B2F577815A34AB" modified="2016-11-30" version="1">MLLGEALIDLDGKSWAMANILPFRSKMQTRLASLGYREDKTGIKGHEFHHSVRESEQKLEPYLQIDRGDQGVCYKNCRASYVHWYFASAPEVISKWLSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQG2</accession>
    <name>A0A1D3RQG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_313795_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000996">
        <property type="protein sequence ID" value="SCN47789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4750" checksum="520B607E025AFCB2" modified="2016-11-30" version="1">MMGFKAFHSAQATIAGIEAAHMIRKGQLSEENIPAYKKFIALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQG5</accession>
    <name>A0A1D3RQG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BAZMOX_87659_1</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000926">
        <property type="protein sequence ID" value="SCN47687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="17"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="108"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="234"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="255"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="276" mass="29859" checksum="AB0D0E7AEEF42523" modified="2016-11-30" version="1">MNYTAPINVKPFLDEDIGSGDITVAIISETMQASAKLITREPMVCCGQDWFNAVFKELNADIEIEWLVAEGQWVEAGMLLCTLRGLARPLLTGERTALNLLQTLAATATYAHQYANAVAGTGCKVLDTRKTIPGLRNAQKYAVVCGGCHNHRMGLYDAVLIKENHIMAAGSIAKAVAKARQISDKWVEVEVENMDELQQALDARPDRIMLDNFSVLQLLEAVKKVAGTVALEASGNISLANIREIAETGVDYISIGALTKNVTAVDLSMRIDLVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQJ1</accession>
    <name>A0A1D3RQJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosome hibernation protein YhbH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_06712_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000943">
        <property type="protein sequence ID" value="SCN47717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="97" mass="11092" checksum="9A836B126DF297CD" modified="2016-11-30" version="1">MQVSITGHHVEVTEAMKQHVEEKIGKLKRHFDNVTDVHVILTVEKLEQKAEATVQISGATLFADDVQDNMYTAIDNMVDKLDRQIIKHKEKIQARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQN1</accession>
    <name>A0A1D3RQN1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="8" type="ORF">BAZMOX_00676_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="118" mass="13375" checksum="33067D7F71C17C14" modified="2016-11-30" version="1">MARIAGINVPDHKHADIALTAVYGIGKPTAINICKEVGIERTIKIKELSEEQLDAIRETIGKIVVEGDLRREVSMNIKRLMDLGCYRGIRHRRGLPLRGQRTRTNARTRKGPRKPIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQN2</accession>
    <name>A0A1D3RQN2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_437497_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001058">
        <property type="protein sequence ID" value="SCN47879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="7748" checksum="377F68AAE3F59CAF" modified="2016-11-30" version="1">MANFPVAYCGLKIITSLSLRFPDFQREYQTVPELRSGLKRYFEFYNQERLHQSLGYKTPSEVHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQV8</accession>
    <name>A0A1D3RQV8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="17">BCAT</shortName>
            <ecNumber evidence="17">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ilvE</name>
        <name evidence="18" type="ORF">BAZMOX_17185_0</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 17">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 17">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 17">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 16">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 17">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 17">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 17">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 15">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="17"/>
    <dbReference type="EMBL" id="FMJP01001088">
        <property type="protein sequence ID" value="SCN47918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17 18" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 17 18" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SCN47918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="308" mass="34910" checksum="C6380E8F48539820" modified="2016-11-30" version="1">MMTMDDRDGKIWMDGEWVEWRDAKVHVLTHTLHYGAGVFEGLRAYHTDQGPAIFKLEEHTDRLFRSAHIMNMTIPFAKEEINQAHRDAISKNNLDSAYIRSMCFYGSEGMGLRADNLKVHVMIAAWNWGAYLGVESMEKGIRIRTSSYTRNHINSTMCKAKANGNYINSILALQEALSAGYDEALLLDHQGFVAEGSGENLFIVRNGILYTPETTSALEGITRDTILTIAQEQGIEVKEKNMTRDEVYVADEAFFTGSAAEVTPIREYDDRKIGSGSRGPVTEKIQTLYFDYVHGRRSDHEEWLARIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL63</accession>
    <name>A0A1D3RL63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Resolvase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_331105_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000016">
        <property type="protein sequence ID" value="SCN46410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00398">
        <property type="entry name" value="RECOMBINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="6">
        <location>
            <begin position="5"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="4 5">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="102" mass="11670" checksum="9624C93702AA8F66" modified="2016-11-30" version="1">MNNFRTYAYLRASTKEQNADRAKGSLQQFASEHNLVISTFFTENESGASIHRPELFRLLEIAQKGDIVLVEQIDRISRLKDDDWNSLKSIIKTKGLRVASLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL66</accession>
    <name>A0A1D3RL66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">folE</name>
        <name evidence="7" type="ORF">BAZMOX_15316_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000053">
        <property type="protein sequence ID" value="SCN46455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="180" mass="20208" checksum="1FD06E9B4D965518" modified="2016-11-30" version="1">MEEHFSKIIEAIGEDVTREGLVDTPKRAAKAFEFLNNGYNKTLEEVLNGAIFEADTEDMVIIKDIELYSLCEHHLLPFVGKCHIAYLPQGKVLGLSKLARIVDMYARRLQIQEKLTKQIADAVDTAVGAKGVAVVIEAKHMCMMMRGVEKQNSVMTTSVMTGIFRKEMSTRAEFLSLINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL71</accession>
    <name>A0A1D3RL71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_255958_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000025">
        <property type="protein sequence ID" value="SCN46423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="232" mass="26174" checksum="0A1B42F1BC53A2FC" modified="2016-11-30" version="1">MALAAFLAEQSILDTSSGIVFDDPVSSLDHIHRDRVAERLATESLNRQVVIFTHDIAFLVLLEETCRETRDRAAIPIAYRVVSRGADAAGFCNTESPANVLPVDKVIKQMQKHLTNVKICHERGEQANWRRKVGSFQKELREAWERAVEDAVSPVIKRMAKKVQTDGLIRLTVLHEKDCLDMREAYGRCSQLLHSQPGELNPRLPTPTDIETEITALETWVHSIRDPQSNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL73</accession>
    <name>A0A1D3RL73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_76886_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000022">
        <property type="protein sequence ID" value="SCN46416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="345" mass="38833" checksum="AD208807362957CA" modified="2016-11-30" version="1">MKSEKINISIFILKLKNVLSSYENVRYFSLLFGENGLANGIHFRCLLSNLTNLNQVGVDEESKMRKVLLSMVLAGMFMSQSISADMSDDIREEMYEAGRQFAKKMMATIPTLENKSVDGWSTEMEAFDYKVPCDATLAPYSAIIAQGTNRMDLLTEDEDGEYTYERDVSISYPRMEEFCIALAQPKSGLSTVENAQGEPEKWRTWWLSEAVEVSDEDWDPYNIAPIRDEDNEIAATIAALKLAKETLGKPTYLVMGNDLGVLTAKIIRKLGEDGEIDVIDGFIYVNRETGEFRRYNRDGSIWKSADNTPPAAAAAAALARHDKRMRGLVVRDDSSRTYTLSRSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL76</accession>
    <name>A0A1D3RL76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_208044_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="PTM">
        <text evidence="4">Binds 2 heme c groups covalently per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000059">
        <property type="protein sequence ID" value="SCN46465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024167">
        <property type="entry name" value="Cytochrome_c4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000005">
        <property type="entry name" value="Cytochrome_c4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 6" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920212" evidence="7">
        <location>
            <begin position="24"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="25"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000005-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="189" mass="20118" checksum="2E2768FF2A7B7472" modified="2016-11-30" version="1">MNLSTKLISRIFLGLLFSSTVLAAPDINAGKESASVCFNCHGAEGNSTNSNFPTLAGQKPAYLANQLRAFRDGQRDNAMMKNIASSLSNKDINNLAAYFASLKNKGAGGDKELAEQGKSKAPMCFGCHGNGAQGMGVAPRLAGQHPAYLQRQLRAFKEGTRKNGPMRGIAGMLSDEDIRAVTEYMGSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLB1</accession>
    <name>A0A1D3RLB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Copper resistance protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11757_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000058">
        <property type="protein sequence ID" value="SCN46463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="134" mass="15072" checksum="630EBA18338138F3" modified="2016-11-30" version="1">MGFWESMLENGEILQHRIATLLVFLLGSMELRARMIHNPSSKLPYVFPLLCAVGGLMLLTHSHIGFQVKSAFLIQIGHTFMGLFALVMAVGRWLELKLDDPGKSIAGFVSVFAFFTGWYDFNFLSRTALLKNAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLB6</accession>
    <name>A0A1D3RLB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_272466_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000087">
        <property type="protein sequence ID" value="SCN46505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018531">
        <property type="entry name" value="DUF1993"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922">
        <property type="entry name" value="PTHR36922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09351">
        <property type="entry name" value="DUF1993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="168" mass="18872" checksum="893FE8DE838EDE59" modified="2016-11-30" version="1">MSLTMYQASIPSFLRMLDNLSAILDKAATHAEVKKIAPSIYVNGRLTPNMFPLSRQVQIATDMVKGCAGRLAGIEVPSYEDNEVTFPELQARIIKTKAFLESVSALQIDGSEDRQVKVKFGSRELNFLGQAYLFDFVIPNFHFHLTTTYAILRHHGVEIGKKDYIGNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLH1</accession>
    <name>A0A1D3RLH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrite reductase [NAD(P)H] large subunit</fullName>
            <ecNumber evidence="5">1.7.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_06966_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.7.1.4" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000090">
        <property type="protein sequence ID" value="SCN46512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="4">
        <location>
            <begin position="60"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="3">
        <location>
            <begin position="132"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="347" mass="39364" checksum="F67DF398AADB4AD1" modified="2016-11-30" version="1">MVNKIKSFNELLEKYGKGRGCEVCRQAIGSILASYWNDYILQPEHLSQQDTNDTFLANMQKDGTYSVVPRMTGGEVTPDGLIAIGKIAKKYKLYTKVTGGQRVDLFGARVDQLPLIWKELIDAGFESGHAYGKSLRTVKSCVGSTWCRFGVDDSVGLAVELENRYKGLRSPHKIKFAVSGCTRECAEAQSKDIGVIATEGGWNLYVCGNGGMKPRHGDLFATDLDKETLIKYIDRVLIFYTRTADRLQRTSVWMENMEGGLDYLKSVVIDDKLNICADLEEQMQHVVDTYQCEWKTTIEDESKLKRFRHFINSDKTDENIIFVEERGQIRPANEDERQHFALVEEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLH7</accession>
    <name>A0A1D3RLH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General secretion pathway protein K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_00699_6</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP K family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000100">
        <property type="protein sequence ID" value="SCN46523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005628">
        <property type="entry name" value="GspK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038072">
        <property type="entry name" value="GspK_central_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38831">
        <property type="entry name" value="PTHR38831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03934">
        <property type="entry name" value="T2SSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002786">
        <property type="entry name" value="XcpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158544">
        <property type="entry name" value="SSF158544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="308" mass="34413" checksum="1AB658F42752798F" modified="2016-11-30" version="1">MKSNKGLALIVVLWVITLLTIMASSFALTIQRESAIISGIKEKAEAQALAEAGINYAVVMLFNTNAEQQWQSTNSLYEVNYAGKNIRILIADESGKVNINYADKQQLLDLLNFAQVEEAQADSLSDAIIDWRDKDDLIGLNGAEEQQYKDAGLKYRPRNNLFNSVEELQMVLGMTPKIYQQIEDMISVYTKKAAINPATASRSVLLTLPDATEALVDEYMQQRAENQRNKQAVVAPDWYNSASATSNVYMIISEAMIERGSTAATMAVIRKGQAKNGLPFQILKWVKDYSVRSLFLPENDQWIINSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN4</accession>
    <name>A0A1D3RLN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_10816_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000144">
        <property type="protein sequence ID" value="SCN46573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="95" mass="10543" checksum="51576C39A2BA3DD8" modified="2016-11-30" version="1">MYAQSKKINCVIHAHSTEIWQATQALELPHTLANIAYGTPEMAEAINQLFQSEQLQQHSLFTMLGHEDGVIAFGDDFAQTACTLINLLAKSKQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP4</accession>
    <name>A0A1D3RLP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein 60 family chaperone GroEL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_53815_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000155">
        <property type="protein sequence ID" value="SCN46583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="236" mass="24953" checksum="197B7A48883D07B9" modified="2016-11-30" version="1">MAAKEVKFGDDARSLMANGVNILANAVKATLGPKGRNAVLDKSFGAPTITKDGVSVAKEIELEDKFENMGAQMVKEVASQTSDIAGDGTTTATVLAQSIVNEGLKSVAAGMNPMDLKRGIDLAVTKAVEAIIASATPCTDNKAIAQVGTISANSDESVGQIIAEAMEKVGKEGVITVEEGSGLDNELDVVEGMQFDRGYLSPYFINNQESMSIELDDPFILVFDKKSLISVIYYQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT1</accession>
    <name>A0A1D3RLT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_32210_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000178">
        <property type="protein sequence ID" value="SCN46622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024392">
        <property type="entry name" value="DUF2688"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10892">
        <property type="entry name" value="DUF2688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="72" mass="7995" checksum="568DA6013F01C8F4" modified="2016-11-30" version="1">MRKNSIQFFSLPCKGGCGKEITTTNRSIHGLDVLHAKYAGYCSDCSPLSEQEIALKQGRALAEKFYQTNSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV3</accession>
    <name>A0A1D3RLV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_21399_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000191">
        <property type="protein sequence ID" value="SCN46646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4527" checksum="C54C6D05B192AE05" modified="2016-11-30" version="1">MKWHLIMTVRIWSWLIPVGFIDSAVEESLDSIGEALARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW2</accession>
    <name>A0A1D3RLW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dolichol-p-glucose synthetase, (Glycosyltransferase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_83548_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000055">
        <property type="protein sequence ID" value="SCN46457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="374" mass="41023" checksum="7890676D242ACC08" modified="2016-11-30" version="1">MPCLNEEETLAVCIEKAQIFIQKNNIEGEVLIADNGSTDGSIAIAESSGARVVHVPTRGYGAALQKGIEGAKGEFVIMGDADDSYDFSNLMSYVEQLRAGYDLVMGNRFKGGIAKGAMPFLHKYLGNPVLSFLGRLFFKIPVGDFHCGLRGFRRDTALSLGLTTPGMEYASELVVRMALAGGRIKEVPTTLAQDGRSRPPHLNTWQDGWRHLRFLLMFSPRWLFFYPSVVILIFGLLLTVLLTQGAVHLTPNITLDIHSMIVGCFCVLVGVQGVSFAIVARRYAALRGFLPFTNQMRYLVNLLTLERVLIVAALFFLGGMVGLAYCSINWFSVHLGPLEYGSLVRILMLSGTSVAIAVQLAFTSFLAEILEIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX6</accession>
    <name>A0A1D3RLX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Probable TonB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_49042_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000207">
        <property type="protein sequence ID" value="SCN46672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="9">
        <location>
            <begin position="56"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="143" mass="16198" checksum="C989660E1A80304F" modified="2016-11-30" version="1">MDALRRQVSELGAKIRYQKPSSKKNRIKFVNSVSAHKYLAAQYITDWQRKVESTGNLNYPAFAKRLGFSSSLTLDVGIKPDGSLYSMRIRKSSGYPALDEAAKRIVRVSAPFPPLPKDLLQELDVLVITRVWKFSDETGLHTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ2</accession>
    <name>A0A1D3RLZ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="3">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tadA</name>
        <name evidence="5" type="ORF">BAZMOX_04566_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000071">
        <property type="protein sequence ID" value="SCN46487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14437">
        <property type="entry name" value="MafB19-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="161" mass="17735" checksum="286B216524098582" modified="2016-11-30" version="1">MGITAEDEAWMRHAIRLAQRAEEQGEVPVGAVVVMEGQCIAEGWNVPITTHDPSAHAEMVALRLAGKTLANYRLMNSTLYVTLEPCVMCMGAIAHARVKRVVFGALDEKRGAICSALELANADFLNHQVDWQGEVLAETCADLLRDFFRAKRRKAKLSVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM26</accession>
    <name>A0A1D3RM26_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-grasp_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_06146_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000227">
        <property type="protein sequence ID" value="SCN46704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003806">
        <property type="entry name" value="ATP-grasp_PylC-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016677">
        <property type="entry name" value="UCP016817_carboligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02655">
        <property type="entry name" value="ATP-grasp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016817">
        <property type="entry name" value="UCP016817_carboligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp_3" evidence="1">
        <location>
            <begin position="93"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="341" mass="39101" checksum="0071D23C4796F825" modified="2016-11-30" version="1">MLAELAYKADYKVIVIDLFADQDTLAIAEQVCRVESLGLPEVRSAIELLQLYFKIQLVVYGSGLEGQQSTLIWLAKNFQLIGNKPRAFERFRDKKDFFKQLNEFSIQFPESRFLPPNDTSRWLIKPIDHVGGIGIRESRLGANTNEYYQRFCQGQVGSVLFCADGQRVSTVGFHRQWPVNQDDFAFAGVIRDQILLETEQNRVTGWLEKLVGHYCLQGLGSLDFIWDGRQCYFLEINLRPPVSLMLYPELDLMGAHISGQLPTQLKDKSIRAMQVIYAMQLSVVKSWVEWPEWSFDRPKNNSCIQAGQPICSIMAQGKTVQQTLIQLSDRQKIIENTILNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM47</accession>
    <name>A0A1D3RM47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00985_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000183">
        <property type="protein sequence ID" value="SCN46629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="60" mass="6814" checksum="D45752717482579B" modified="2016-11-30" version="1">MRFSDALGCDELINVRCGVVYSRKLAQDQCQIGLGFLDLDADAEVRLTQFIQNRKRAHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM90</accession>
    <name>A0A1D3RM90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rep</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_91846_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000182">
        <property type="protein sequence ID" value="SCN46628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="27"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="315" mass="36211" checksum="6F967B1FEE323AB2" modified="2016-11-30" version="1">MYNLKKQYSETSFSSCRHITVEKSVYLTVVKSNKVIEASYLLSLSEQRVLLACIAQIDSTAELTEQYQFQVSAGQIADLVGLDNIANAYRDLKKSAEKLYERSVIINDPDPDNPKITERKTRWISSIDYIPGEGKLVLNFAAGIIPYLSRLSKEFTKYKLMHVARFESIYSIRLYELLVQWSSAGEREIEVEWLKKQFQVENKYKRLGDLKRRIIEPAIAEINKHSNLWVKYGQRKSGRTVTHFQFQFGLKDQPKPRKQITEDEINKAARPGESRASVIARLSGTKVDDFAKPGESLDQALARKWALQGVKKKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA0</accession>
    <name>A0A1D3RMA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylornithine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01616_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000313">
        <property type="protein sequence ID" value="SCN46825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="463" mass="50959" checksum="1816CD774994E14D" modified="2016-11-30" version="1">MAFSIAELFTQHNQEKFELHEKHLNNQMVRVLQTIGYDRTYTKATGQYLYDQDNQEYLDCLSGFGVFAVGRNHPTVVSALQETLTLELPNLVQMDVSLLSGLLAKKILETTPDNLSKMFFCNSGTESVEAAIKFARYTTKREKIVYCDHGYHGLTMGSLSLVGEEVFREGFGPFLPGCSSVPFNNLEALEGALSNKDVAAFIVESIQGKGVNIPDDNYLPEVERLCKKYGTLFVADEVQTGIGRTGKFWAIDHWGVKPDMICMAKALSGGFVPVGGVAMTSKIMDTVFNRMDRAVVHGSTFSKNNMAMAAGLATLQVIEDESLVENCAQVGTDIINSINAMAPKYEFLKEARGKGLMIAIEFQAPKSLKLKAAWAALEAANKGLFCQMVTIPLFKEHHLLTQVAGHGMNVVKLLPPLNLTNKDRDWIVNSFEHAIADTHKVPGSIWTLGKNLASHALKAKKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB0</accession>
    <name>A0A1D3RMB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_292994_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000291">
        <property type="protein sequence ID" value="SCN46793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="82" mass="8920" checksum="08691E95D679D4BA" modified="2016-11-30" version="1">MSHVVPCLLNKENNAKGIPKNENNDAAGSIQLSANEIKANKIETTPATDASGDMIFSNIAKINFLLFQCNLHFNIIICSESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME5</accession>
    <name>A0A1D3RME5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00523_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="180" mass="20490" checksum="FE6B89E25C3D7940" modified="2016-11-30" version="1">MHALMQAVIDTGTLGLVTLKPLSQMRSANKKHGNIGDIELLEDMEIIESWDAKYGKAYLREEIDEVIEKLTTHNSVGVVGFVTTLAPIINQEIIKKLDSAKQLHGIDIKILTFEEWIELIFNRALEEKHTTEIELAKNWLLAYTECIAQKRRDVAPIDEPCIEWVKELDQKLILTAKANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF5</accession>
    <name>A0A1D3RMF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iojap protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_05000_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000317">
        <property type="protein sequence ID" value="SCN46843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="83" mass="9271" checksum="474BFA3BB55E60E5" modified="2016-11-30" version="1">MVIATGTSARHSKALCEYVTLALKEQGVMPLGVEGGQDSEWVLVDLGDVILHVMTAQSREFYQLEKLWSVENTQSEENEDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI7</accession>
    <name>A0A1D3RMI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03276_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000342">
        <property type="protein sequence ID" value="SCN46874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="47" mass="5165" checksum="7E9971997F28A4CF" modified="2016-11-30" version="1">MQIRPITMRAATPKIKLEPSALHLIASGVVDQSKTIKIKAKAIRILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM6</accession>
    <name>A0A1D3RMM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-hydroxythreonine-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.262</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_10183_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.1.1.262" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000264">
        <property type="protein sequence ID" value="SCN46758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="127" mass="13461" checksum="B0D5B54103BF9199" modified="2016-11-30" version="1">MCGLNPHAGEGGHLGREEIDVIEPVLNQCRASGINLQGPLPADTLFTDKYLVNADAVLAMYHDQGLPVLKYKGFGKAVNITLGLPIIRTSVDHGTALDLAGTGKADAGSILYALQTAMQMSSHLDKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN2</accession>
    <name>A0A1D3RMN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase (Flavoprotein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02486_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000370">
        <property type="protein sequence ID" value="SCN46923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015904">
        <property type="entry name" value="Sulphide_quinone_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632">
        <property type="entry name" value="PTHR10632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="418" mass="46149" checksum="64DBAC0FC10A913A" modified="2016-11-30" version="1">MPERHHSLLIIGGGAAGVSVANNMRRKNQSIDIALVEPSEKHYYQPGFTIIGGGAYTLKRATKNEKDLIHSSVTWIQDYAKSFQSKDNKVTLKSGDVISYDFLVVCPGLQLDFNKIDGLVETLGKNGVCSNYSADTVEYTWEVLQTIESGNCLFTQPPMPIKCAGAPQKIMYLAADRFRKKGTADKVNVEFLNAGPGMFGVPFFAKALNKVIKEYAITTHFNHNLLAIDGPAKIATFETTDADGNKSTVTKEFDMIHVTPPQSAPDFIKTSPLANDAGWVDVHPGTLQHTVFGNVFGLGDVTSTPNAKTAAAVRKQVPVVVDNILKLQESQELVEGYDGYGSCPLTTSLNTVMLAEFSYGGKVTPSFPFLDPRTNNRLWWFGKTFGFPWLYWHIMIKGLRFDIPHKVSYAEKFTKEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN8</accession>
    <name>A0A1D3RMN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heat shock protein 60 family chaperone GroEL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_36330_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000361">
        <property type="protein sequence ID" value="SCN46906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="145" mass="14534" checksum="3C0EC45140B03156" modified="2016-11-30" version="1">MHSTRAAVEEGVVAGGGTALVRAISALEGLEGINHDQKVGVDILRRAMSAPLRQIVANAGDEASVVCNEVANGSGNFGYNAATAEYGDMLAMGILDPAKVTRTALQNAASVAGLMITTEVMVADAPSEGGAPAAMPDMGGMGGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP0</accession>
    <name>A0A1D3RMP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_51220_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000387">
        <property type="protein sequence ID" value="SCN46942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="50" mass="5587" checksum="B8223C13E8289F88" modified="2016-11-30" version="1">MPPSRTAIAAHFGLANFPVAYCGLKIITSLSLRFPDFQRVKELLKTCYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ5</accession>
    <name>A0A1D3RMQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_28787_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000287">
        <property type="protein sequence ID" value="SCN46788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005534">
        <property type="entry name" value="Curli_assmbl/transp-comp_CsgG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03783">
        <property type="entry name" value="CsgG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="313" mass="34634" checksum="1204C08533BE9656" modified="2016-11-30" version="1">MQKIIILLVGFLCAEVLWATPAKQPTMAVLPFQLSPVIDTMNIGEMRVTRTMAEREFSNQLIEFLAKSRKFNMLSRTQIDKVMDENRLTESEWALPGQVEMMAKLLVADYLVTGVINRLETAAVSQNIAITGETRPRLVTTFKIQFQILQSSTGKIVLADQVINKLRSDEVRRDIPALERRYWTAADYKDLLFTRTATEVGNAILAGIYPIKVNKVSNNEVILNRGSGAGIEVGQYYLVLNQGEAITDVDTGELLGGAEIQVGMIEVMSVARKLSKAKIISGAGQIGIGDICRLQKSIRGDTEAAYPRVTPGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ8</accession>
    <name>A0A1D3RMQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_48536_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000425">
        <property type="protein sequence ID" value="SCN46981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="5138" checksum="974FF1B2E8B843FF" modified="2016-11-30" version="1">MQNAKQIELGAPVRITAYQLLKTQQKTDCGKNRQTLLSSMKRMNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR5</accession>
    <name>A0A1D3RMR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome c-type biogenesis protein CcmE, heme chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_01705_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000295">
        <property type="protein sequence ID" value="SCN46798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017003">
        <property type="term" value="P:protein-heme linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004329">
        <property type="entry name" value="CcmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036127">
        <property type="entry name" value="CcmE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34128">
        <property type="entry name" value="PTHR34128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03100">
        <property type="entry name" value="CcmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82093">
        <property type="entry name" value="SSF82093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="covalent" evidence="4">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604329-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="9693" checksum="903E6C6CEC78D0CD" modified="2016-11-30" version="1">MVVDGSLKRSTDSLRVSFELTDYENTVKVVFTGILPDLFREGQGIIAQGKMDAQGVFQADEVLAKHDENYMPPEIAESMKAKKEVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS1</accession>
    <name>A0A1D3RMS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_406235_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000428">
        <property type="protein sequence ID" value="SCN46991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="1">
        <location>
            <begin position="16"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="10391" checksum="6C558DDC047832FF" modified="2016-11-30" version="1">MISFKGTHFPKDVILYAVFFYVRYGVSYRDLEEIMEERGVNVDHATLNRWVIRYAPTIAAKAQSQKRNTNRSWRMDETYIKVKGKWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS8</accession>
    <name>A0A1D3RMS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_16778_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000435">
        <property type="protein sequence ID" value="SCN47005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="112" mass="12741" checksum="9FC8FC704A61975C" modified="2016-11-30" version="1">MVSDVEASLYFYTQILGLQQMERPDLGFPGAWFQLGKNQQLHIIKLPNMDPTTGRPEHGGRDRHVALTVDDFDRVRETLDKNNIVYSMSKSGRKALFVRDLDANAIEIIGHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW6</accession>
    <name>A0A1D3RMW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11027_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000445">
        <property type="protein sequence ID" value="SCN47013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="54" mass="6423" checksum="F1AC8FF350012BAC" modified="2016-11-30" version="1">MLTKKKKTTKQNRTKNKQHKISNRPEKKDKTRAEKVETLVTNSKQTLIVIHMYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW7</accession>
    <name>A0A1D3RMW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable acyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_57597_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MetA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000325">
        <property type="protein sequence ID" value="SCN46848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00295">
        <property type="entry name" value="MetA_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033752">
        <property type="entry name" value="MetA_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20919">
        <property type="entry name" value="PTHR20919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04204">
        <property type="entry name" value="HTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000450">
        <property type="entry name" value="H_ser_succinyltr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3 4">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for acyl-CoA specificity" evidence="3">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000450-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="352" mass="40544" checksum="8330ED5E2C2AE53D" modified="2016-11-30" version="1">MPIILEKNSTIAKSLINEGVDVISKEDAVHQDIREMHIGILNLMPDAALRVTECQFIKLIASCNKIIQIRIHIFTLNEIERSNETKKYIDISYETFDQVRKDGLDALIITGAPPFNEDILSEVYSESLAKVISWGLKNVTSIWVSCLSAQYVAKKNLNIDRKKMNRKLWGVFPHTICDSTHPLVKNMNSKFNCIHSRIYDVDETELQRHGFKTLIKCDVNQQFLLAVSPDGIKTILCQGHPEYDTISLFKEYKREINQYLKGIRLDYPPLPIAYFGKETEQTLNKYKKFLQQDDCTLNSADFLEDYFSHSEIYNTWIDTSKALFGNWIGLVYHMTGYERNDPGIKGEGLKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX3</accession>
    <name>A0A1D3RMX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_85891_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000462">
        <property type="protein sequence ID" value="SCN47041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="100" mass="12322" checksum="262038F1EF32E0DB" modified="2016-11-30" version="1">MTSEDSRQKSRRRLERRASERRRITHKFGSPAWINAVKQNYLLWPKQDRRVKDNRSQERRRNYRRIKHLAHTASIVKREQLHNLLTEEEKIMLNELMQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX7</accession>
    <name>A0A1D3RMX7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1863 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01466_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000330">
        <property type="protein sequence ID" value="SCN46858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036490">
        <property type="entry name" value="MTH538_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015032">
        <property type="entry name" value="MTH538_TIR-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08937">
        <property type="entry name" value="DUF1863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52206">
        <property type="entry name" value="SSF52206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1863" evidence="1">
        <location>
            <begin position="5"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="137" mass="15339" checksum="069C14956BCC7917" modified="2016-11-30" version="1">MTDPRAFISFDFDHNETEKTLFVGQSKNSKTPFTIQDWSAKSSMPQSQWEAIVKEKINKTNMLIVLVGKYMASAIGVAKEISMAKDQNVPVFGIYVGGANTSSNLPKGLQRNRTIAWDWEKISNAIDQMMCEGKNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN54</accession>
    <name>A0A1D3RN54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_366682_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000525">
        <property type="protein sequence ID" value="SCN47121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="158" mass="17547" checksum="4D80181A033C718E" modified="2016-11-30" version="1">MHRIWSDGRWNKITIAHGCYWAKCSFCDISLDYIGKYDDAGADITVQRIQTLIAETGQTGFHFVDEAAPPKALFALAKKLIEQDIVITWWGNIRFEKTFTAEKCQLLADSGGESLFLRKLVLGIPAQASGKNLTRLVNAFGAPIRPRHLVPTQQGVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN55</accession>
    <name>A0A1D3RN55_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="11" type="ORF">BAZMOX_57089_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000548">
        <property type="protein sequence ID" value="SCN47145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01128">
        <property type="entry name" value="rho_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="10">
        <location>
            <begin position="48"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="181"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="418" mass="46946" checksum="1816BCB81A980B50" modified="2016-11-30" version="1">MNLTELKLKPITDIIALAESLGIENVSRTRKQEVIFSILKKQAKSGEDIYGDGVLEILQDGFGFLRTPGSSYLAGPDDIYVSPSQIRRFSLRTGDTISGKIRPPKDNERYFAMLKVEKINFEPPENAKHKILFTNLTPLFPNKRFIMERGDGSSEDLTGRVIDLIAPIGKGQRGLIVSPPKAGKTMILQSLAQSIAENNPECYLIVLLIDERPEEVTEMERCIRGEVISSTFDEPASRHVQVAEMVIEKARRLVEHKHDVVILLDSLTRLARAYNIVAPSSGKLLSGGVDANALEKPKRFFGAARNIEEGGSLTIIATALVDTGSRMDEVIYEEFKGTGNMELHLERKIAEKRIYPAIHINRSGTRREDYLVSPDELQKTWILRKILQPMDEMAASEFILGKLKDFKTNAEFFESMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN71</accession>
    <name>A0A1D3RN71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_36330_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000361">
        <property type="protein sequence ID" value="SCN46907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920260" evidence="1">
        <location>
            <begin position="22"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="248" mass="27091" checksum="B73C0FFA686707DE" modified="2016-11-30" version="1">MTTFKLLLASVPLLLSSHANAELYNVQLVFTDDTTFTGTFDYDPATQTTNNLQGKLDDVLMGNIEEIKYQLDAQSDGQGGITAYAYALETMDIETNPPINNNVMVAINFNATDPTLGATDESQLAYVDCSAGALMGNTCMYYLTWHNPIIPMAGGHGLLSQTITLANGGDTTSSYDCLFTWAENNYADLFAPAAASQSLPPYYYRYYSTQNVYLGVNTHDNHVYYLDADNTLSDVGPLSKWLPLAGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN77</accession>
    <name>A0A1D3RN77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease BN</fullName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_14423_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000403">
        <property type="protein sequence ID" value="SCN46958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="411" mass="46563" checksum="57F7E5271C815125" modified="2016-11-30" version="1">MHNKIIDYFHDGLWQSHKEEKNSDIKKFALRYLKIFTLSANGFIKDHGNLRASALTLYTLLSIVPVIAMCFGVAKGFGFEKTLEQQLLEQVPDQDTMILQLIEMARNMLDSTKGGLVAGFGVVLLFWTVIKVISNIEESFNHIWNVQKPRTMGRKLSDYLSLMLLAPVLIIAASSISVFVQAQLTSLINEFALPGTITALHILSYLPMLILWLLFSFLFMFMPNTRVNYSSGIFAGIFAGTVFYILQSLYVSLQIGVSSYNAIYGSFAALPLFLVWLQITWMIVLFGSELSFFHQNIALYQFNQKFKNLNFNSKNQLALHIMHAIIERFSKTTKLPYSAEDISLHLQLPISISKSLLTELSNCKLLSKVYYEDNPEPHYQPAYSIGLLSDEEITKALKNNGESYTITVNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN79</accession>
    <name>A0A1D3RN79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Restriction endonuclease (HaeIII)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_35689_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000508">
        <property type="protein sequence ID" value="SCN47096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019059">
        <property type="entry name" value="Restrct_endonuc_II_HaeIII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09556">
        <property type="entry name" value="RE_HaeIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="327" mass="37571" checksum="CF198C792A011296" modified="2016-11-30" version="1">MVNNSLQMLTGKAFEYAILSEFKEKLQSMTTVEVIENNAYEVAQNCFNELQHQEQGRYLLTASFAVNFLMDIEPRLANDVDKNDVLQLEILTDYQGQLGDVRDILAIRSVQKWEIGVSAKNNHRAVKHSRLSNDIDFGEKWLGAKCSRTYFSEINPVFNHLKTIQQESNKTEKWNSLDDKNAMVYVPILDAFKKELYRIYLTNPSKIASSLIEYLVGNKDFYKVIKSDNAVEIQAYNLYGTLNLPFQNVQPKFKTPKITLPSEVLDISYKVNSQTTLIVTFNNDWVLSFRIHNASSRIEPSLKFDINLITAPHSLFINKLSVPQELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN94</accession>
    <name>A0A1D3RN94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_363172_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000561">
        <property type="protein sequence ID" value="SCN47161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="70" mass="7623" checksum="D8714E70D10F9CED" modified="2016-11-30" version="1">MLRDALIRAVNVSGDAGVFAILVHALTDQAKLFYLSCGFIESPIQPMTLMMTIATVRSILVEVGLFIPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA1</accession>
    <name>A0A1D3RNA1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusB</name>
        <name evidence="8" type="ORF">BAZMOX_02217_5</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000520">
        <property type="protein sequence ID" value="SCN47116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="145" mass="16605" checksum="986AC1A7727B5EC4" modified="2016-11-30" version="1">MSSAKTKARQCAVQALYQWQMTGTDLSTIARQFAEDQRLKNAQKSYFTDLFHGIPKDLDKIDFAMKDFIDRAVNDIDPVERAILRIGVYELLHKPETPYRVIINEGVELAKYFGADGSHRYVNGVLDKVAQIQRKLEIEAKLKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG7</accession>
    <name>A0A1D3RNG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_433033_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000571">
        <property type="protein sequence ID" value="SCN47186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="64" mass="7126" checksum="C6542DE41F88A521" modified="2016-11-30" version="1">MLSERRDEDAATAFFKQAINNNGFPDKVVMDKSGANYAGLANINLSLKTRGKRSDSEVMIFSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI8</accession>
    <name>A0A1D3RNI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04316_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000451">
        <property type="protein sequence ID" value="SCN47027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="347" mass="40096" checksum="CD284F0234F5AF0B" modified="2016-11-30" version="1">MIRVIHDLQELSENPYYPSQLPKLANSAQVKAQNYSVLMGYDFHITENQEVKLIEVNTNAGGLWFACGIEDPLNQALPDKLAQQLLDTFIQEYQLFTQDLQARPKFIAIIDQVPEQQFLYPEMQAFAQLFKQAGIECVIIDLSEININNSKLYYQEQHIDLIYNRHCDFYLTTPEMQIVAQAWQRQSVCLTPNPRVYGLLADKQRMADWSQSTLLNDLLKPKVAQRLQQAIPKTQLLHTLDRNTLWSERKRLVFKPTTSYASRGVYIGEKLTKGKFNGFDLQTTLVQERIKPSIIRTNDGTQFKVDFRLFVYRHTILTACARIYQGQVTNLRTPNGGFSQLKLSNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ8</accession>
    <name>A0A1D3RNJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01117_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000457">
        <property type="protein sequence ID" value="SCN47037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="274" mass="31995" checksum="5ACBFB9A300723C8" modified="2016-11-30" version="1">MGVLDQLRKEADQKKLSEQETVDQQALRAKLYKTQVLPKMQQIFKYLQELAEHLNYLEVPVQVENYSDRFPRLGTLMQKDYKINTDGYGGFSDFNKLVQINLTFYCIGKGELEYNVQTKSAIEQENAFLHAKRVASKMYRLGGAGREESAKFVVTKKIPVRVRFEVDYEQSQIKVMVNNHTDFSTYTEVWQPADIDDAFLDTLARYLLRKDSEFVSLDITDEDRNELRKKLQSIKHKEEQERLRGVTEQKNSGLEKKEKLGDKMKSFITGKINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK8</accession>
    <name>A0A1D3RNK8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rep_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_110340_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000541">
        <property type="protein sequence ID" value="SCN47139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="50"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="391" mass="46567" checksum="CB1EA01435B173DD" modified="2016-11-30" version="1">MNQELNELRIVNKQFSVGEYDQSWSKIERYLFIEIYDTVKDFFMDRADEKISEFGSNHITVKVPVKLIREKFLNGGNKARQLLDVADSLSKKRVGFTKKAEKSDEIGFRFVTMFPQIAYNPDSRNQELFVEIHSSVYEEMVPIESYCQLELKLLSEFTSGNTIRLYEIFKSHSFRTQFSIWFDDLRGMLGFRVEGKYTEWKYFNAKVLKPAIQNINSYKEYDIEVSYKKIRGDDRIDFHITSHKKRDFNPVAVLNLNQTINPETRESNRIQRKYIETVIETCAKRVEITNKGELREWIVSDIINQQQNTDTEFNWKKALNEISKQIRFGQYTEPYCHKYLPDSSAKFDEDIYQKIKTLESRGYYKKIKDMFTEEQIIANRFGFILDRCQPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM5</accession>
    <name>A0A1D3RNM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00434_9</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="181" mass="19497" checksum="5216B8DE462B798A" modified="2016-11-30" version="1">MGLLDSVFGKSKVNAANKKVKAAREANDPVALEKALTSAITIYQSIGSDSSVFKDALYNWGMALLYSARLKKQDAEAIVLYEEAGKKFSFCLVAKPDYLAAALDWGVVLMELAALQKGATQAASYALAKEKFTLANSIQKGVASYNFACLHAVEGDFDACKAALELARDYGNLPDEQDILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP4</accession>
    <name>A0A1D3RNP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_06368_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000636">
        <property type="protein sequence ID" value="SCN47292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="213" mass="22924" checksum="5DB63249E471BC61" modified="2016-11-30" version="1">MSKVIAILNQKGGVGKTTIAANIGVSILKRGHSVLMVDSDPQGSLRDWNATNEGELVSVIGLDRETLAKDIEGVKAPYDFVIIDGRAKAEKMAGAAIRAADIVLIPVAPSALDIWGASDITEAIAARHEVTEGKPQTRFIINAATKNTKLIEEIRPATEESGFKPLDTVLYSREIYKQTMGEGLTVHSGKNADALEEIENLTTEIMEILNNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT3</accession>
    <name>A0A1D3RNT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Similar to LReO_3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_296935_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000650">
        <property type="protein sequence ID" value="SCN47304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="191" mass="21439" checksum="7D1CD8CFEEA91EBD" modified="2016-11-30" version="1">MNLLISDIDGIDAYINDVIIYSDSWEQHLMTIRKFYERLTEANLTVNLDKSEFCHGTVTFLGHVVGQGQAKPVLAKIQAISDFPVPACRKQLMRFLGMAGYYRKFCSNVSDISGPLTNLLSKKVKFIWDENCERAFCKIKAILQTEPVLSAPDFYKSFKLAVDASDIGVGGVLLQEDTDGIDHPACYFSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT6</accession>
    <name>A0A1D3RNT6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="4" type="ORF">BAZMOX_10545_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000565">
        <property type="protein sequence ID" value="SCN47168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="86" mass="9843" checksum="26560DB1F97AFD46" modified="2016-11-30" version="1">MSKNTDQVRTITGRVVSNKMDKTVTVLVERLIKHPVYGKYIRRSTKLFAHDENNVCNEGDVITITSCRPYSKNKSFILVDVQSKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU6</accession>
    <name>A0A1D3RNU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_468786_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000686">
        <property type="protein sequence ID" value="SCN47352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="7656" checksum="4C1DA8AE1F2EB8E4" modified="2016-11-30" version="1">MGVDQSVVFPLPPEFLTPQDGHNKQDCEIAAATRWLESYAPLCKAYDIVLLADDIFCHDPFCKQLMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW8</accession>
    <name>A0A1D3RNW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_15154_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000694">
        <property type="protein sequence ID" value="SCN47372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="5065" checksum="10AA7E403FF1D815" modified="2016-11-30" version="1">MGFLASLGGTVKKYWKIGVHWLAALRDLLALPFDAKAWHILKISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY9</accession>
    <name>A0A1D3RNY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_16045_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000715">
        <property type="protein sequence ID" value="SCN47393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="115" mass="12953" checksum="07AFCDECED79ED5A" modified="2016-11-30" version="1">MAISLTIPKVSEPVRVNFKLREDLVKNFNLYVKAAKEVNPSCDESIVLEAILEHHLKRDKEFKKWLKNYSPDADSDETKSGSSDVKGDEKKEKTKSSDFQSGMSSTIKDATLETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP00</accession>
    <name>A0A1D3RP00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_136743_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000695">
        <property type="protein sequence ID" value="SCN47374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="159" mass="18178" checksum="37357A876780F8C9" modified="2016-11-30" version="1">MSVIQLKKCTLPKTNIKHYLTAITALNIYSEDGTGDWHFSENFLEDGDFIPRKTVAGVDTCSTNEYLGNNGVFNCYQILVESGIQPSTKDVFSADHYRAIADMVLDGITKGYDIESSIILDDWLPEQHEKEKLYCLIDSFKPALTEKQWQKITSWKMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP18</accession>
    <name>A0A1D3RP18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_392425_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000578">
        <property type="protein sequence ID" value="SCN47197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="5322" checksum="C28876DFCF004B03" modified="2016-11-30" version="1">MANFHVAYCGLKIITSLSLRFPDFQRMCYSFKLHLNKKTINTLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP29</accession>
    <name>A0A1D3RP29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_156761_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000614">
        <property type="protein sequence ID" value="SCN47248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4945" checksum="D04D6DE3B31FE636" modified="2016-11-30" version="1">MIVCFVDIGGIVVITAIIHISPYCDWSYLHNSETHRSLNGQLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP40</accession>
    <name>A0A1D3RP40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_79136_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000656">
        <property type="protein sequence ID" value="SCN47309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="124" mass="13729" checksum="3AD48DF0F9B8F463" modified="2016-11-30" version="1">MSAVLRQFEFMAKLASSSVLLIHHEGKGSLNDSDAGTAASRGASAITDNARWHMRLQRMTRSDAENRGVLEDDERRRWIRVTNEKANYGEEMSEAWLLRGEAGVLSSSVPLIKTKNANGGRRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP43</accession>
    <name>A0A1D3RP43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_241654_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000733">
        <property type="protein sequence ID" value="SCN47416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="119" mass="13635" checksum="0B7ED01BE275C227" modified="2016-11-30" version="1">MIRERKSYSLAMAQIEKDFTQAINNHFSQSFQEGQKVLVSFVQFDRMRDVDELKACIESLPLTKSVAVGSIENRGVVYEVIYLGNPNDLQLDIMKKSREFRLRGLRAKSNNGGIIAFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP66</accession>
    <name>A0A1D3RP66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_54647_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000786">
        <property type="protein sequence ID" value="SCN47483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="53" mass="5938" checksum="2790DDAF22038730" modified="2016-11-30" version="1">MISMRVSGTKPKWRTTDLRAPTGGAGEWVRAMTMKGQQDTGKHYVIEQSLTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP72</accession>
    <name>A0A1D3RP72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_08714_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000645">
        <property type="protein sequence ID" value="SCN47298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="6060" checksum="1E38C6DAB50248D0" modified="2016-11-30" version="1">MAQKVVNIRVDDQKWERFKKIAKHNESDASKEIRKAINKYLSENAQLDLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP81</accession>
    <name>A0A1D3RP81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.129</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_53790_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.3.1.129" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000613">
        <property type="protein sequence ID" value="SCN47247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="6">
        <location>
            <begin position="177"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="263" mass="28949" checksum="599BD99C74210A2F" modified="2016-11-30" version="1">MTQNIHPTAYIAEQAILGKNITVGPFAVIESPAQIGDNCKIGAHAVVMPYTKMGSGNTLHPHVVLGCLPQDTSFKEETISWLDIGNDNVFREGFTAHRASEENGTTLIGSNCFFMNNSHVAHDCQIGNHTIFANNVAIGGFVQIDDRVFMGGSVVAHQFCRIGSYAIVQGTTGLNKDVIPFCLIAGYPAKHYRLNTIGLKRSGITGDRYKIISIAFRRLRNNESIDDLEDTEEIAYLKQWLAIKSKRGLHGFMGLGQNKLRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP82</accession>
    <name>A0A1D3RP82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01131_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000799">
        <property type="protein sequence ID" value="SCN47510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4433" checksum="20F2369EED660BB0" modified="2016-11-30" version="1">MPPSRTAIAVHFGLANFPVAYCGLKIITSLALRFPDFQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF6</accession>
    <name>A0A1D3RPF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00594_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4751" checksum="F174176AAB1A726E" modified="2016-11-30" version="1">MLGSVFSKCAIYAVILQGTGAHFWYDFSWYFNEPCTARNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG3</accession>
    <name>A0A1D3RPG3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor P-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_35182_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the elongation factor P family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000839">
        <property type="protein sequence ID" value="SCN47583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00646">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011897">
        <property type="entry name" value="Transl_elong_p-like_YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="9">
        <location>
            <begin position="69"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="8">
        <location>
            <begin position="132"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="189" mass="20954" checksum="C21FE6B62FC0BF50" modified="2016-11-30" version="1">MPKATDLKRGMIIDINDVPHAIKQLEARSPSSRGAGTAYKVRYTNLKTGQKLDEVYKGDDFLKEADCIQVKVQYSYNDGENYVFMNMDDYSQYNLNQDDLEGQKEYITEGLEGITALIMEDNILGIELPASVDLEIIETAPGIKGSSATARTKVAILPTGLEVQVPEYLETGEIIKINTTTGKYMSRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG8</accession>
    <name>A0A1D3RPG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_72545_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000718">
        <property type="protein sequence ID" value="SCN47398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="38"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="131" mass="14564" checksum="2B0B5EE582FE0309" modified="2016-11-30" version="1">MLVTAFFAVTFFLIQDIIESSTRKYQTISPMLTVAKLNSGNPIIIDVREANEFKKGHISGAIHIPLSSIEKQLKKIELYKKDDVIVVCHTGTRSASACSTLTKLGFENVFLMTGGMQSWEENKLPVVTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH5</accession>
    <name>A0A1D3RPH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_71251_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000756">
        <property type="protein sequence ID" value="SCN47439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="36"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="193" mass="21946" checksum="41ECD7933C0D6D7A" modified="2016-11-30" version="1">MEERGVNVDHATLNRWVIRYAPTIAAKAHSQKRNTNRSWRMDETYIKVKGKWVYLYRAVDSQGDTLDFMLSERRDEDAATAFFKQAINNNGFPDKVVMDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIIVQDHRFIKKIIKPMMVFKAFHSAQATIAGIETAHMIRKGQLSEENIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK2</accession>
    <name>A0A1D3RPK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
            <ecNumber evidence="8">6.1.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_35182_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.1.1.15" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000839">
        <property type="protein sequence ID" value="SCN47584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_2b" evidence="5">
        <location>
            <begin position="7"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA_edit" evidence="7">
        <location>
            <begin position="99"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="HGTP_anticodon" evidence="6">
        <location>
            <begin position="317"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="413" mass="44644" checksum="012B59F5BA14B7A6" modified="2016-11-30" version="1">MLILFILSQESLQATYDIMHTAYHAIFNNFGLDFRAVIADSGSIGGAVSHEFHVLAESGEDAIAVSTESSYAANVEKAEALMPTASRSAATQDLTLIDTPNQHSIEELTQFLNVSAEQCLKTLIVKGEEEGSLVALLLRGDHELNDIKVEKIDGILTPLAFASDEEVAAACQCKPGSIGPIGLSIRTIADRSVTILSDFVCGANQEGKHYTGVNWERDLAPPAEIADLRSVVAGDPSPNGKGVLNIVRGIEVGHIFQLGTKYSSAMNATVINEGGKSEVMTMGCYGIGISRIVAAAVEQSHDDNGIIWPAKLAPFTVALCPMNMHKSERLRVAANQLYQDLLEAGVDVLFDDRKVRAGFMFSDMELIGIPHRIVLGDRGLDNNSVEYRARTDSENRDIPLNEIVTFIKEQTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL0</accession>
    <name>A0A1D3RPL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_164073_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000882">
        <property type="protein sequence ID" value="SCN47631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="7121" checksum="B8BA28FB8F9CC9FD" modified="2016-11-30" version="1">MPPSRTAIAAHFGLANFPVAYCGLKIITSLALRFPDFQRLVVLQEYWHIPDCSNFIFLTVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL2</accession>
    <name>A0A1D3RPL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methanol dehydrogenase large subunit protein</fullName>
            <ecNumber evidence="8">1.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_18015_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyrroloquinoline quinone</name>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial PQQ dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.-" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000887">
        <property type="protein sequence ID" value="SCN47640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017512">
        <property type="entry name" value="PQQ_MeOH/EtOH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001479">
        <property type="entry name" value="Quinoprotein_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01011">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03075">
        <property type="entry name" value="PQQ_enz_alc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00364">
        <property type="entry name" value="BACTERIAL_PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0634">PQQ</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="443" mass="47704" checksum="C6EA16AC0D66C605" modified="2016-11-30" version="1">MTNTQAPLVVKGKVLTGIAGGEFGVRGFLAAYDMKTGQLAWKGYSMGPDGDTLINPGKSTTWENGKVTKLGKNSGTSTWEGDQWKIGGGTTWGWYSYDPELNLVYYGSGNPSTWNPVQRPGDNKWSMSLWARDADTGEVKWVYQMTPHDEWDFDGINEVALVDQKINGKMRKTAVHFDRNGFGYTLDRVTGELLVAEKFDKSVNWATHIDMKSGRPVLDLRYSTEANGEDENTVGACPAALGAKNQQPVSYSPQTGLFYISGNHLCMEYEPFEVSYTAGQPYVGATLSMMPAGKDVLTGKPDGSTNLGQFTAWDATTGKIAWSNKETFSVWSGSLATAGGVVFYGTLEGYLKAVDAKTGKELYKFKTPSGIIGNVNTWSYKGKQYVGVLSGIGGWAGIGIAAGLDSGEEDSNSEGLGAVGAYRSLSSFTKLGGVFTVFALPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM5</accession>
    <name>A0A1D3RPM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_25926_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000788">
        <property type="protein sequence ID" value="SCN47489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="56" mass="6272" checksum="E20E7309EB67C27B" modified="2016-11-30" version="1">MAFYFVSTFATAQTQTKQWPYGYRGLPALAFALHGWQAGLSEENIPAYKQLMALEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN4</accession>
    <name>A0A1D3RPN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amylopullulanase</fullName>
            <ecNumber evidence="3">3.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_306538_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000874">
        <property type="protein sequence ID" value="SCN47614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="2">
        <location>
            <begin position="36"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="185" mass="20477" checksum="85F3D230FD78500E" modified="2016-11-30" version="1">MGETVKLSDARIQRLIAKERNFTLHDRLEIIEVIGELLSTVICRYKSLATKGRIELSVTPYAHPIIPLLLDIKSTHEAMPGAPLPELDTYPGGEERAKWHIKQGLVTFKRFFGFIPEGCWPAEGAISTPTLKIIQEAGFSWTATGGQVLHNSLSLSGLGSDIGVHHPFQVKGTKIPSLKIRETER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP5</accession>
    <name>A0A1D3RPP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04194_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000798">
        <property type="protein sequence ID" value="SCN47509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4818" checksum="168A5BF80CA0D447" modified="2016-11-30" version="1">MLISHNRTGNFSILFFISKVSEILKSDGGDIEEEVQDGDIDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP6</accession>
    <name>A0A1D3RPP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative conjugal transfer protein trbL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_02191_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000875">
        <property type="protein sequence ID" value="SCN47616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030255">
        <property type="term" value="P:protein secretion by the type IV secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007688">
        <property type="entry name" value="Conjugal_tfr_TrbL/VirB6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04610">
        <property type="entry name" value="TrbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="377" mass="38393" checksum="4A2FB88F52FBFCCD" modified="2016-11-30" version="1">MFGLYWALGAGQILDAIKKILFIGIWFWIVSSFPVLVNQFVNSLIQAGSTAAGGLTFNLLDPSAIAGKGLDVSQPIMDKVEALPWTQIGQKIIISILYLIVMAIFLLIAIQVFITVLEFYLIVAIVSIFLPFGLMKHTKFLAEKSIGAVIASGIKMMVLSFILSVSGPVILAATLTATATLNEIFSLILTVGAIGFLAWNAPGIAAGLIAGSPSLSAGTAVQNTVAGGFMAAGAAAGLANATRAAASMTGGAARLGAAAYGSASTGANLALAASNSTNPVNRAASAALGSLYGMGSAAGNQVKNTVSNMAGKAGETLSNASTNGARVAMGMDKKTMAASTSSEAPAWAKRTMQRAASMHHSIPQEARPSGGNINPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR4</accession>
    <name>A0A1D3RPR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Programmed cell death toxin ChpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_40515_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000927">
        <property type="protein sequence ID" value="SCN47690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="104" mass="11039" checksum="FB42BA870C825466" modified="2016-11-30" version="1">MCLNPTAGKEITGDYRPCLVLSPKAFNRLGITLIAPITQGGNYARFEGFTVTLMGSGTDTQGVVLISGIRMADLVARKATKVETAPSEIVDEVLAILTTLVEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT2</accession>
    <name>A0A1D3RPT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04194_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000798">
        <property type="protein sequence ID" value="SCN47508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="149" mass="16893" checksum="E78012452EE05DB9" modified="2016-11-30" version="1">MYNRSEGEGEDEGEGDKISDYYDAPPKDEPEKQVSYYATIDGPSNYDGPVINEEQDVSVVNGYQDVGNTYNHINHSRNSDFKELGYDTAALGDSEMMLNDYDVAQRVIFRNNVTNYDTNASTGMYDRTDHSGVTKQLEHYDTVSKIFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT5</accession>
    <name>A0A1D3RPT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_07964_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000929">
        <property type="protein sequence ID" value="SCN47701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4752" checksum="7EC99ECDAC045501" modified="2016-11-30" version="1">MDDRQLDAMFSGVIGQEYDTLKLICPLAAKMSHAENQGNGAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV7</accession>
    <name>A0A1D3RPV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00594_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="116" mass="13199" checksum="AB463554C86A3629" modified="2016-11-30" version="1">MDITPYLKLMVDKKADSLIFSLSSAPRLRLLEQEKPVGNTILNHEMLNDIFQALTEDTQKLQFSIDKKIRFVSPLFGSQDFIIDAIETDNELSITISIDKRQAAIKNTPPLKAYKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW4</accession>
    <name>A0A1D3RPW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_87659_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000926">
        <property type="protein sequence ID" value="SCN47686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="15765" checksum="8F3E736C2BA37BA7" modified="2016-11-30" version="1">MFFIWLYAGKGASETTSQPEESAVEHKEVATETTEVTPEVESVEPVTEAVVTNETEENCVAVSVVPQDSTLRRHYMQNLMANKEDASKKIPEDSALRRHFTQQLCVEIAANMVDRPTDPTLKRHYDAQLSSAVADRLEALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW5</accession>
    <name>A0A1D3RPW5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_46996_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="FMJP01000956">
        <property type="protein sequence ID" value="SCN47740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="9"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="351" mass="38563" checksum="17DD18BFFACBF25D" modified="2016-11-30" version="1">MQMTTQKILVTGGAGYIGSHACVALLEAGYDIVVVDNLSNSSIESLVRVKQITGKMPIFVQADIRDKKALTDVFSEHTIYAVMHFAGLKAVGESCVQPIRYYQNNVYGTLVLTEVMQEFSVKKMIFSSSATVYGEPDTVKYSEELPVFGATNPYGKSKAMIEDILRDLSTADGLTKASQPWEIILLRYFNPMGAHESGLIGEDPNGIPNNLVPYVSQVAVGKLVQLSVFGGDYPTVDGTGVRDYIHVIDLVKGHLAALKALDDLSLNIGCKAYNLGAGKGYSVLQIIAAFEQVTGKNINYKIVDRRTGDVAENYADPSLALRELNWKTEKNLEDMVEDTWRWQSQNPNGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY0</accession>
    <name>A0A1D3RPY0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase</fullName>
            <ecNumber evidence="9">4.2.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Beta-hydroxydecanoyl thioester dehydrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Trans-2-decenoyl-[acyl-carrier-protein] isomerase</fullName>
            <ecNumber evidence="9">5.3.3.14</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fabA</name>
        <name evidence="10" type="ORF">BAZMOX_01376_2</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(2E)-decenoyl-[ACP] = (3Z)-decenoyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:23568"/>
            <dbReference type="Rhea" id="RHEA-COMP:9639"/>
            <dbReference type="Rhea" id="RHEA-COMP:9927"/>
            <dbReference type="ChEBI" id="CHEBI:78467"/>
            <dbReference type="ChEBI" id="CHEBI:78798"/>
            <dbReference type="EC" id="5.3.3.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(3R)-hydroxydecanoyl-[ACP] = (2E)-decenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41860"/>
            <dbReference type="Rhea" id="RHEA-COMP:9638"/>
            <dbReference type="Rhea" id="RHEA-COMP:9639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78466"/>
            <dbReference type="ChEBI" id="CHEBI:78467"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the thioester dehydratase family. FabA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="9"/>
    <dbReference type="EC" id="5.3.3.14" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01001010">
        <property type="protein sequence ID" value="SCN47805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034017">
        <property type="term" value="F:trans-2-decenoyl-acyl-carrier-protein isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01287">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00405">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010083">
        <property type="entry name" value="FabA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272:SF8">
        <property type="entry name" value="PTHR30272:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01749">
        <property type="entry name" value="fabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="171" mass="19056" checksum="C1E4ED860118E74C" modified="2016-11-30" version="1">MQKQHSYDREELLKSGRGELFGPENAQLPLPNMLMMDRITHISDTGGEFDKGEVIAELDITPDLWFFDCHFQGDPVMPGCLGLDAMWQLVGFYLGWKGGPGKGRALGVGEVKFTGQVLPDAKKVTYKVTLKRVIMRKLVMGIADATMEVDGKVIYVAKDLRVGLFTNTKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ3</accession>
    <name>A0A1D3RPZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_441872_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000866">
        <property type="protein sequence ID" value="SCN47609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="67" mass="7719" checksum="C1BBFF247C33B782" modified="2016-11-30" version="1">MDLVDFSKTISLPLYGLKDGEYKYIVNDEFSGVFNVSNDNLSSDKQLVSFPDDDAIFDEMDDWRTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ06</accession>
    <name>A0A1D3RQ06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Precorrin-3B C17-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_229414_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000930">
        <property type="protein sequence ID" value="SCN47702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="153" mass="16686" checksum="B64F7068A444A943" modified="2016-11-30" version="1">MITPRGYANKYNSLTGATKEGEQAGVSLSMGLEGWYACLRQYVQDNPGLTLEIADYFGVVMGEVLAAIAAGESAGEHKAARVAQDKLNDVVSACQSWGRLRGIIRAEAGAVSELFLQAQDFQLRGDWLNIETDAFSLSYQLEQSSCRLFSQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ29</accession>
    <name>A0A1D3RQ29_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xseA</name>
        <name evidence="10" type="ORF">BAZMOX_06203_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000808">
        <property type="protein sequence ID" value="SCN47537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="9">
        <location>
            <begin position="12"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="8">
        <location>
            <begin position="128"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="314"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="450" mass="50625" checksum="335817A13D5DCD77" modified="2016-11-30" version="1">MDSFSHSATKVFSVSQLNSSVKSLLEQNFFAVQVSGEISNLSRPSSGHIYFTLKDERAQVRCAMFRSQVQRLKFQPENGLQVQASANVSLYEARGDYQLIINQLQETGDGALRHAFEQLKEKLAAKGLFASEHKKTLPLIPTCIGIITSPSGAAIRDILSVLKRRFPIIPIIIYPVMVQGDEAKYAINQAIINANQRKECDVLILARGGGSLEDLWAFNEEMVAKAIFKSRIPIVSGIGHETDTTIADYVSDLRAATPTAAAEHCTPDVQQWLGQFQAYEYQLTQLIQNKLLQHTHHLDWVTKNLNQQHPGKRLQIQAQRLDELELRLKSTLQNQLNQARSNLKAHHAQLWQFNPAHKIQHLKNYYITLNNRLSSSINNKLHEQQQKLTLLSQALNIVSPLATLHRGYTLTSNEENVLLRSSAQLKVGQTIKTRFSSGTVTSIIQEVNHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ50</accession>
    <name>A0A1D3RQ50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_122810_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000993">
        <property type="protein sequence ID" value="SCN47784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="125" mass="14009" checksum="B1A122E4C3DFBC11" modified="2016-11-30" version="1">MLSERRDEDAATALFKQAINNNGFPDKVVMDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIIEQDHRFIKKIIKPMMVFKAFHSAQATIADIETAHMIRKGQLSEEYIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ73</accession>
    <name>A0A1D3RQ73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_30273_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001000">
        <property type="protein sequence ID" value="SCN47796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="8"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="49" mass="5392" checksum="486BC12FE33160F4" modified="2016-11-30" version="1">MFFFVFSGYGRAYFSCTSAHTCTGDGTAMVARAGLQNEDMEFVQFHPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ78</accession>
    <name>A0A1D3RQ78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BAZMOX_07461_1</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000893">
        <property type="protein sequence ID" value="SCN47648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="102"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="222"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="341" mass="38529" checksum="F056B1216C07B404" modified="2016-11-30" version="1">MPILANVLFKLDNNLLTLTGTDLEVQIVVDIAFDNDEQGSITIPARKLLDICKSLPSALDIKFELVKDKLKVQSGRSRFSLSTLEAHDYPDFEMTAMDCQFTIKTAQFKTALDKTAFCMANQDIRYYLNGIMLGIFNRQLKLVGSDGHRLSIYEGEIETETGIESRIIIPRKGVLELTRLLDNDPEQEIQVEFSKNNIRVVIENLTFSAKLVDSKYPDFSKVFEQSFNSPVHVQKQVLKDALTRVSILSNEKFRGVEFVIEGNNLQISTNNPEHEEADEEIAIEYQGEALSIAFNSQYILDAVSNLDSEMAVLTIAENLSSCFIEESSGQNYKFIVMPMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA1</accession>
    <name>A0A1D3RQA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02191_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000875">
        <property type="protein sequence ID" value="SCN47617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9876" checksum="73123EF1982BDFAB" modified="2016-11-30" version="1">MKYLLLIPLILTVLNGCSQEEVDAANYVKEKTLKEVSLDKKTEYFKNHQDELKLQRNKCNKMPRQEFKSSSDCQAVLRAINSLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB8</accession>
    <name>A0A1D3RQB8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="6" type="ORF">BAZMOX_00676_5</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="126" mass="14425" checksum="B5C2F7E472537548" modified="2016-11-30" version="1">MRHRKSGRQLNRNSSHRKAMFSNMATSLFKEELIRTTLPKAKELRSIAEPLITLSKNDSVANRRLAFAKLRDRDMVTKLFNELGPRYQARPGGYLRIMKCGFRTGDKAPMAYVELVDRPELGAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC7</accession>
    <name>A0A1D3RQC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_40515_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000927">
        <property type="protein sequence ID" value="SCN47688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="59" mass="6482" checksum="B691EE3BB140F1DB" modified="2016-11-30" version="1">MPEDKAYFAFTISCDRTGFKAFHSAQATIAGIETAHTIRKGQLSEENMPAYKQFIALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD0</accession>
    <name>A0A1D3RQD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1,4-alpha-glucan (Glycogen) branching enzyme, GH-13-type</fullName>
            <ecNumber evidence="2">2.4.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_07384_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.4.1.18" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001038">
        <property type="protein sequence ID" value="SCN47856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-amylase_C" evidence="1">
        <location>
            <begin position="217"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="312" mass="36482" checksum="F76670864E5C1088" modified="2016-11-30" version="1">MLYLDYSREEDDWVPNQYGGNENLEAIDFLRELNTVTHEQHPGTVVIAEESTSWPQVTRPTWTGGLGFSMKWNMGWMHDILSYMQQDPIHRRHHHDQLTFGMLYAFTENFMLPFSHDEVVHGKGSMLNKMPGDEWQKFANLRLLYTFMFTYPGKKLLFMGCDIAQGTEWNFNQSLDWYVLDYSYHKGIQTLVKDLNKLYVKHPALFQHDFDNQGFEWIDCHDVEQSIISFTRKTEQETLIVILNFTPVPRENYRIGVPRPGTYHEIFNSDSEYYAGSNTGNGYIVSEDTPWMNQEQSLNLTIPPLAGIVLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQG9</accession>
    <name>A0A1D3RQG9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein HflK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_29552_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">HflC and HflK could encode or regulate a protease.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">HflC and HflK may interact to form a multimeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the band 7/mec-2 family. HflK subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001005">
        <property type="protein sequence ID" value="SCN47799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03404">
        <property type="entry name" value="SPFH_HflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010201">
        <property type="entry name" value="HflK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020980">
        <property type="entry name" value="Membrane_HflK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF2">
        <property type="entry name" value="PTHR43327:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12221">
        <property type="entry name" value="HflK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01933">
        <property type="entry name" value="hflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PHB" evidence="7">
        <location>
            <begin position="77"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="359" mass="39175" checksum="C91FC5D03D41A643" modified="2016-11-30" version="1">MSWNEPGGDKKKDPWSGRNEENGPPDLDEAIRSLQDKLGGLFGGNSGGGNGNNEASPPSLKGLGFLALGAVALWGASGFYVVDEGNRGVELRFGKYITTTQPGLNWHFPAPIETVELVNISQQRFLEVGYRSGGARGTSGQGSVAKEALMLTKDENIVDVRLAVQYQVNDAKKYLFNILNQTATLKQVTESAERGVIGGNTMDFVLTEGRSQVVIDIKKDIQQVMDSYDSGILVTSVNLQDAQPPEQVQSAFEDAIKAREDKQRLINEAEAYANDVVPKARGGAARLTQESEGYKSRIISAAEGEVSRFTQILKEYKKAPEITRKRIYLETMESVMSATNTVMVDVKDGNNLMYLPLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQL1</accession>
    <name>A0A1D3RQL1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Autotransporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_42425_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001091">
        <property type="protein sequence ID" value="SCN47922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014262">
        <property type="entry name" value="Extracellular_HAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02913">
        <property type="entry name" value="HAF_rpt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autotransporter" evidence="1">
        <location>
            <begin position="325"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="595" mass="63353" checksum="4829B362A51799AE" modified="2016-11-30" version="1">MLGLGGTEASGVSGDGKIVVGYKTNNSRIEAFRWTSGGGMVDLGFLDSNAHTDAQGVSRDGSTVVGYSSITSSGGTANDTKAFRWTEKGGMEELKDLNGNFIAAQARAVSGDGSVVVGATSKTYEAFIWTKAGGIEILSTDFPTDSSSDAFGISTDGSVVVGYHQDSGGHLEAFRWTKAGGLKNLGDLPGGDKSSLASAVSGDGNVVVGESRSGRADEAFRWTQSGGMQSVSEWLTDNGVIATPIISTALGTNDDGSVVVGELDKKNRKQGQGAYIARVSKIGTGLITVLDLQDSLASLAQGISAFQSSNIIINGAHDRPMSHHVSEGKNTVWLSGNWSYDGRNTRDGMLGLAEISGGHNFGPAQVNISLGKTWYRKNLIRNGKIDSYGNYVMVEGIIPIPIDSGLYATIGTYYQWGDSDIHRSYINSGARDTSKASPDMDTWSVRVRVDWESALTMASIQFSPYVDLSYIHSHLDSYTETGGGFPAHFNSRNKKNTELHAGFNMGIPLFTTSFQLVTNIEVAHRFDHEDARISGKILGLSSFDLLGHKYDPTWVKGGVGVEGKLGIGKVSLMLNGTTEGEMPSAWFLTSYQIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQN6</accession>
    <name>A0A1D3RQN6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_67521_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000995">
        <property type="protein sequence ID" value="SCN47787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="247"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="459" mass="49046" checksum="D5470646275B168F" modified="2016-11-30" version="1">MHREASAREKAEADAKIVAQKKVDDDARAELEKKNKVSDEERLAAEKAKRLEESVERNAAKVRKQAAAKKAAAERKAGGGAARKPTAGGAARKSGVAAVPGGGRNAAKPATTVHRRADKPAGGTKTSYGKKGRKRTGRGKGGNEHQFVAEAKHAFAMPTEVVAKDIKIPENIVVSELALKMSVKAAEVIKHLMKLGIMSTINQSIDQETAVILVEEMGHNPIMTSEDDHETGMLAEHTEADEREEFARAPIVTIMGHVDHGKTSLLDYIRKTRVADAEAGGITQHIGAYQVVTDHGSVTFLDTPGHAAFTAMRARGADVTDVVIVVVAADDGVMPQTKEAVEHARAADVPIIVAMNKMDKPEANPDKVMQELAALNVVPEEWGGDVQFIKVSAKTGEGVDNLIESLILQTEILELKAPKEGKASGLVVESRLDKGRGAVATVMVQKGTLEQGQISFMWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQN7</accession>
    <name>A0A1D3RQN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P) transhydrogenase alpha subunit</fullName>
            <ecNumber evidence="2">1.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11819_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001070">
        <property type="protein sequence ID" value="SCN47889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_C" evidence="1">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="66" mass="7258" checksum="F3C53FF1DA440BF6" modified="2016-11-30" version="1">MENKILNFQESGAGEGGYAKDISEMSQEFRDAQIALYAKQCKEVDIVITTALVPGRKAPILITKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQP2</accession>
    <name>A0A1D3RQP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_486537_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001001">
        <property type="protein sequence ID" value="SCN47797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5608" checksum="717A21B9991A2D74" modified="2016-11-30" version="1">MCAFKADHDFILCALGNKDELSQNSPINATENPQLTYACDSPPPFNEHKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQQ5</accession>
    <name>A0A1D3RQQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DedD protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01607_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001034">
        <property type="protein sequence ID" value="SCN47848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="2">
        <location>
            <begin position="87"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="166" mass="18641" checksum="560577AA5A871D1F" modified="2016-11-30" version="1">MNEILKQRIVGAIVITALAAIFVPMLFDDPVSDADSYTNELSLPQQPIDNTQELLDSIPKTSREVLSRPKPAQVNLQAQQIKKSAQQANLESWIIQVGSFSQKQNAIEFRDKLRKNKFTAYVDSVNSDQGTLYRLLVGPELGKKIALKTQQRLESLYKVKTLLVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQT7</accession>
    <name>A0A1D3RQT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Colicin V production protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_01607_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01001034">
        <property type="protein sequence ID" value="SCN47847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="163" mass="17745" checksum="07614B04FE4554E0" modified="2016-11-30" version="1">MIWIDYAIIGLISISLIIGLFRGLVREAFALVTWGIAFWVGLTFSSPFANLLKNTVTIESVRIAVAFASLFILTLIVGAIINHLLSALISKTGLTGTDRLAGLLFGIARGAIIIVILVMLAGLTPLPESPWWVESQLIPHFQALAVWLNTHMPDSIAGYLNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RKZ9</accession>
    <name>A0A1D3RKZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside diphosphate sugar epimerase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01013_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000006">
        <property type="protein sequence ID" value="SCN46395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="328" mass="36854" checksum="7427FD04AE1572EC" modified="2016-11-30" version="1">MTILVTGATGHLGANLVRTLLNRGETVRVLLRKESNNTEVKGLNIEHAYGDLKDEKSLINAVKGCDYVYHLAAFVSIRNGDRKELYDVNVLGTRYLMQACRLEGVKKVVHCSSFGAVGNNPDGASNEKWAVSPYEMTTDYEISKTFAELEVYKEIARGLPAVIVNPSGIVGPWDFKPSLLGRTIIEFAQGKMRGSVKGGFDFVPVQDVVQGHLLAMEKGIVGERYLLTGEQHTINETLDWLEEFTGKPKPKLVIPTFVMQNIAIVKDWVERKFFPHVYPRFNYHSIRLLNCGKFGTHNRAIQELGLNPTPVKEAYRDAVLWFKEHGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL24</accession>
    <name>A0A1D3RL24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_267854_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000018">
        <property type="protein sequence ID" value="SCN46415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="76" mass="8819" checksum="B45BA6997DCEE5C8" modified="2016-11-30" version="1">MTNFKSAQYPKDVILYAVFVYVRYGVSSRYLEEIMKERGLNVDHATINRWVIRYAPTIAEKAHSQKQKTKEVLAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL72</accession>
    <name>A0A1D3RL72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_56150_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000024">
        <property type="protein sequence ID" value="SCN46420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="94" mass="10780" checksum="1C80BC26809CA3B5" modified="2016-11-30" version="1">MAFKDRSIKSDKDTAAEDKFISGADKTSNEIEKEEEIVKLDPNARKKIQVGLKVNDYEMLLIKRLSEKIDRSISGTIRYAINKAIKDHSVKKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLA3</accession>
    <name>A0A1D3RLA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Similar to marapsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_74407_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000048">
        <property type="protein sequence ID" value="SCN46450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920228" evidence="1">
        <location>
            <begin position="31"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="29"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="373" mass="42006" checksum="B5843407D2EA667F" modified="2016-11-30" version="1">MKPNSFIMKPNSFIKLFFFTILIFSNLTLASSENTDDVPSSSNSWPSMVTIYHSTGGDWKFQCDASLIDKNWVLTAASCMKGVSAKELLVIINEESANVHREVSEIIIHAEYSRQDNDYAMLKIKEVPSSVKSIQLAPPYPIESWYWGTTQFKDQYWKTPHWKTPHWETPQVKDLSWDGTVNKVRELDLTRISNSLCSKNEKMSGRYGKDWITDNMICAGQGLGKKETCDGASGGPLIMFRGHTNTWMHLGVSSFGGGCAPYGVYARTSKITRWVSDLMCSNEEVPDIPLSLKSSDNGDKTATIKWSSVSGATGYHLNYRTKNDGSVKSSLDLKENYFITPKWASGRSYYVTVNSYKNNCLSKETKEKYITLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLD5</accession>
    <name>A0A1D3RLD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_275694_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000072">
        <property type="protein sequence ID" value="SCN46491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014464">
        <property type="entry name" value="CvfB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040764">
        <property type="entry name" value="CvfB_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37296">
        <property type="entry name" value="PTHR37296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17783">
        <property type="entry name" value="CvfB_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="158" mass="17932" checksum="53515C3011A95975" modified="2016-11-30" version="1">MDEQHRIAASTELNNFILDEVSYLKEGDKVSLVIAKKTDLGFKAVVDNAFWGVLYYNEVFQSLKEGQKLTGYIKKIREDRKVDLSLNKTGHTHVAPLTQQIMTRLEENNGHLDLSDKSSPEEINAAFGVSKKVFKHAIGVLYKERRITLTKTSITLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLF7</accession>
    <name>A0A1D3RLF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thiamine biosynthesis protein ThiC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_534052_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000120">
        <property type="protein sequence ID" value="SCN46545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5092" checksum="E9F4CE106F3F93E4" modified="2016-11-30" version="1">MKITQEIKTMDKAEIAKINAIQVEMDNKSAEFLANDSEIYMKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLI2</accession>
    <name>A0A1D3RLI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-damage-inducible protein J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_269516_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelB/DinJ antitoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000098">
        <property type="protein sequence ID" value="SCN46516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015643">
        <property type="term" value="F:toxic substance binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044010">
        <property type="term" value="P:single-species biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026262">
        <property type="entry name" value="DinJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007337">
        <property type="entry name" value="RelB/DinJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38781">
        <property type="entry name" value="PTHR38781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04221">
        <property type="entry name" value="RelB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003108">
        <property type="entry name" value="DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02384">
        <property type="entry name" value="RelB_DinJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9453" checksum="A36037772F27C31D" modified="2016-11-30" version="1">MRTDTVVRARIDSDTKERATAALEAMGLSVSDAIRLLMLRIAEEKRLPFTVQVPNASTKKAMEELESGHGKRFDSSDELFDDLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLI5</accession>
    <name>A0A1D3RLI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recA</name>
        <name evidence="11" type="ORF">BAZMOX_15724_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000085">
        <property type="protein sequence ID" value="SCN46504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="9">
        <location>
            <begin position="36"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="10">
        <location>
            <begin position="200"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="66"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="332" mass="35776" checksum="4E0E9573DF893860" modified="2016-11-30" version="1">MDENKKKALGAALMQIEKQFGKGAVIRMGDDTASRDIQTVSTGSLSLDIALGCGGLPRGRVIEIYGPESSGKTTMTLSAIAQMQKVGGTAAFIDAEHALDIGYAEKIGVNVDDLLVSQPDTGEQALEIADMLVRSNAVDIVVVDSVAALTPKAEIEGDMGDSHMGLQARLMSQALRKLTANIKRSNTMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGAIKKGNEIIGNETRVKVVKNKVAPPFKQAEFEIIYGEGVSFLGELVDLGVKYGFVNKAGSWYSYGKDKIGQGKENVRLYLKENPAVATELEAKIRAEVFGVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM6</accession>
    <name>A0A1D3RLM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00589_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000166">
        <property type="protein sequence ID" value="SCN46605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="197" mass="22002" checksum="D9B30357E7169234" modified="2016-11-30" version="1">MDILSLILSCSLSIKFDDNLIQSIIMNESFNNPIYVRVEGSKFGVGYQNKDDSISAINEIMKSGKESYIGLMGIPLSDAINNGYTANDLLDECLNIQLGTANIDMFMDHCKAEGKIDISTCSIKKYAKYTGQKSIIFTNKVIHKGIQFVSKSNQKNENSLIKNQSVHLDIGKGKRSKESVFIDFNIDKERGEILDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ0</accession>
    <name>A0A1D3RLQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_156721_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000079">
        <property type="protein sequence ID" value="SCN46499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="5106" checksum="4B1A7E403FF28E20" modified="2016-11-30" version="1">MGFLASLEGTVKKYWKIGVHWLAALRDLLALPFDAKAWHILKISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT0</accession>
    <name>A0A1D3RLT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugal transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00589_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000166">
        <property type="protein sequence ID" value="SCN46604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="2">
        <location>
            <begin position="18"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="182" mass="20911" checksum="779CBE30B6A99880" modified="2016-11-30" version="1">MEKNIYYLSLKKEPVNLVPVLLVLSTFIFIAIIFMNSGKKYLVYNHTDSIPKGFYYLNNDIDIESVKNGDLIVFDVPDQVKEMVIHRRWLNVNDTLTKPVSAKSGDFVCTNNRTVIVNNISYGPIEEYDSNGREMPWFKYCGTVKKGEVFVFIDNSKSFDSRYYGPIPAAELIAKATPLWIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT8</accession>
    <name>A0A1D3RLT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_32210_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000178">
        <property type="protein sequence ID" value="SCN46623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="59" mass="6877" checksum="F40760F672F15A86" modified="2016-11-30" version="1">MIEFIDIEYQSNAGTKIEAEGYKAGCVKKSSNENPYEKSSWQYDIWEQGRVCSYAFVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ4</accession>
    <name>A0A1D3RLZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_14658_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000244">
        <property type="protein sequence ID" value="SCN46725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005318">
        <property type="entry name" value="OM_porin_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03573">
        <property type="entry name" value="OprD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920236" evidence="2">
        <location>
            <begin position="21"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="427" mass="47490" checksum="6B2E20D6AA1A7184" modified="2016-11-30" version="1">MQAYILSLLVVLSTLHIAIAEDKPEKTPAPTQIQPPAEDLSPGFPYNINTSLRVEGIQHDLKYDDCNGFVRGGYIQTHQKTVSNQQAYGLGGELGCGFSWGSFFKLHASAFTTINPGFNSDNKDEIQGDFFAADKNSYITLGEAVMTLSYANFQAHLGPQRFNSPHMDQDDLRLLPNIFEAYFVDYHIGDELYLGSGFVRTTKGWENNSNAADFVDIGEAFGGKGALSWLSWGKYQQGYIDANIWYYYIKDVQQIFFIDVTYQNWLNNIFFYELGGQFDLGRSVGSQSIGLVDANTLGVYATISAYGVSFTTAFNKNYGASAAVNSVGGGPFFTSMEQMTLDAVNAKNAQALFFNLEYQPLDELIIGAATGDFQGENTADFHTQEVNAYLGFNFRQILTVNFMYAYIKDLQAVQVSEQIRVILGFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ7</accession>
    <name>A0A1D3RLZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antirestriction protein KlcA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00589_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the antirestriction protein family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000166">
        <property type="protein sequence ID" value="SCN46599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004914">
        <property type="entry name" value="Antirestrict"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042297">
        <property type="entry name" value="Antirestriction_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03230">
        <property type="entry name" value="Antirestrict"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="139" mass="15762" checksum="81772D7519130533" modified="2016-11-30" version="1">MCEEVEIVVNSVVVPESIRMNKLPEYFGGKFLICENLIYHYMEKLCSDYQGGYWNFYELSNGGFFMAPSLDAESLNLIWANNYFDGSLSLEAAGIVACLFSYNHMASIGGDDQFINLYHWLLEYSWSHPEGGVIAKAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM30</accession>
    <name>A0A1D3RM30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_03224_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000131">
        <property type="protein sequence ID" value="SCN46558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="253"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="492"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="1049" mass="118500" checksum="BB47F10E3414EAFD" modified="2016-11-30" version="1">MRPEQKSQLLLGVTRSKAKMLEYGIPEEHHIKITQDPAKLFTISIGLLGDLAAAINRNEPDPDSLAELKNNLLFSAHFFDSYLQSKLNDTLDPYLVLLGSASYYLCDLPGSASVLAKRIDDNCPDLDGDGLEDLLLWLLQVKLGTYFEGTEGTFGEFIDSISRFLHQFFDDGTGEDNIFDLAISLREAVYRFGTPRQLLFGDVIVAVLRKKVENSSWKALPLYSGLPRDKWLHALRKDSFIKELWPAQHLLGKAGVLKGESAIIQMPTSAGKTKATELILRSAFLANRVSLAIIITPFRALCHEIKNSLVEAFHNEPTKVDELSDALQADFEIAELLESQQILVVTPEKLLYILRHVPELASHIGILVFDEGHQFDSGTRGITYELLLTSLRSMIPDNTQKVLISAVISNAESVGEWLNGEPNVVEGTSLIPTFRSVGFTSWLDHLGRIEYVDSHDVEQNEFFVPRVIERFNLGKKGKEQKDRYFPEKDDGQAIALYLGLKMAPNGSIAIFCGKKSTAASICKKAAEIIERDIPLPLPQEFSVLKEVKQLHYLHVENLGERASASMSAEHGIFSHHGNTPHGIRLAVEHAMRENRVRFVVCTSTLAQGVNLPIRYLIVTSVYQGMERIKVRDFHNLIGRAGRAGMHTEGSILFADPIVYDKRRTRKDGWRWDIVKELLDPTKSEECASSLFQLIPLIIRNDRNKSKDKKNHTLKWDILSFARAHISGWDSLNEIIDKIAKKYGENGYTADTMRPQFEFFSLTLSSIEGFLLSNWDVTDNGLLEADIVDLAEQTLAYFLAGDEKREQIQELFKLLAENISDNITDINRRKAFGKTLYGVNDAIEIETWVKDNADALLADQNGEDLFDITWPLIAGHIHNRAFNKFDKKDILREISKKWILGTPFHELFRIADKNKCRIGKGKSPRKVKIEHIIDICEGGLAYDGALLMSAICEFVEMLDREGTGDLVNRLQMFQKRLKYGLPTETTIAIYELGFSDRVISQYLATSLNLGGTQNKNIVQVLKQKREETKAIMVRYPSYFQDRMSELLDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM73</accession>
    <name>A0A1D3RM73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferric uptake regulation protein FUR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00299_7</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="16276" checksum="A4CB06F2A6D635B8" modified="2016-11-30" version="1">MGDKRVETQELRDVGLKVTLPRVKILEIMERETHKRHLTAEQVYKILLSENEEIGLATIYRVLTQFEAAGLVNRHHFEGGNSVFELNKGKHHDHVVCVKCGKVDEFTDEVIEERQDQIAKKLGYELTDHSLYLYGLCPNCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM88</accession>
    <name>A0A1D3RM88_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7 8">Dihydroorotase</fullName>
            <shortName evidence="7">DHOase</shortName>
            <ecNumber evidence="4 7 8">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrC</name>
        <name evidence="10" type="ORF">BAZMOX_13356_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 7">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>(S)-dihydroorotate + H2O = H(+) + N-carbamoyl-L-aspartate</text>
            <dbReference type="Rhea" id="RHEA:24296"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="EC" id="3.5.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 8">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="4 7 8"/>
    <dbReference type="EMBL" id="FMJP01000290">
        <property type="protein sequence ID" value="SCN46790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01294">
        <property type="entry name" value="DHOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="PTHR43137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="9">
        <location>
            <begin position="11"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="7">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="345" mass="38636" checksum="44CE6C133B26F2DC" modified="2016-11-30" version="1">MQQLTLTQPDDWHLHVRTGDMLKTVINHTARQFARAIIMPNLQPPATNVDQALSYQQEIQQATSSAYAFTPLMVLYLTNSTTIEDVKKAAESAAVHAFKLYPAGATTNSDQGVTDLQAIFPVFEAMEKYHIPLLVHGEVTDAEVDIFDRERVFIDQKLRVIQQNFPALRIVLEHVTTREAVQFVQETPSNIGATITPQHLLYNRNAILVGGIKPHYYCLPILKRETHRLALVAAATSGNPKFFLGTDSAPHMKHLKENSCGCAGCYSAYGAIELYAEAFEQANALDKLEGFASFFGADFYQLPRNTKKITLEKTDWQVPSSYSISKDLQLTPLRAGETLHWKLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA9</accession>
    <name>A0A1D3RMA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_21399_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000191">
        <property type="protein sequence ID" value="SCN46648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920241" evidence="1">
        <location>
            <begin position="22"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="283" mass="30465" checksum="D49D0C7EDC94C3E4" modified="2016-11-30" version="1">MKLAYTPLAIALLFSMQTAQADLVSDSELLMDNAQKVYATFFPSNEPTQVSPPWRYRFYPATATYLGINQDDSGVYLLGGAFGDSPLYVNKVDAVLTMLNGQLSGAGESKSAICNTSSLPDGFVYTYSGNTVNITTNGQCVKVPDSSNFCDVNPETNASGAPVETNIHVLTATNIQNFELQGISFPGVDDRLKQQMANNKTCIIHAPTEFLNYTVNMDICLDITDTLSGSGIPLSGPVTTHFIGSSVSTQVDDCFATDASSITNIVTQEVWIREATGEFTKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD0</accession>
    <name>A0A1D3RMD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00523_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="381" mass="42633" checksum="E119EA95B613E7B3" modified="2016-11-30" version="1">MRKLSKFRFVIPLVVLGLLPIKSAHAFFLTSFLIGLLVDELVTESTPVEQPKEPEGSDMSDPAVLANYMSQPFNTRFIDAENIDETDEYEFGNCGDNFDGTRIASKYLGYYGRVAGEIAVYGYRNVLVSYYYDGKDGEHDWGELMGSKLSTGIPTYEKETVIIRIADEVGDIWENKLSDLMRIECSNLYIDDPEDDPVNTVYDYGKGFMVLPVVEVIQTGDQFYGSFLPHEGGLRLFDYQVLVPDDTRKSTAKLDTSTGLLLIPELVTDEGTNYAVYYTEDGWTFKEPVATKVDTGTEYGHSYNATDGEPRIASVATSPSTPVLKEKDIEEAEKAFRDAPKFDPDDFHYEKYEGRNQTSFDGLVIPQNAGGIVTSMDSDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME1</accession>
    <name>A0A1D3RME1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycine dehydrogenase [decarboxylating] (Glycine cleavage system P protein)</fullName>
            <ecNumber evidence="1">1.4.4.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_48922_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.4.4.2" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000211">
        <property type="protein sequence ID" value="SCN46678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="8137" checksum="33A977F1FDDA537E" modified="2016-11-30" version="1">MLNNVLHNAPHKHRLLIEEWHFPYSKQQAFFPDKGLHDDKYWPPVGRIDNVYGDRHLYCSCPSIAEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME4</accession>
    <name>A0A1D3RME4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03651_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000246">
        <property type="protein sequence ID" value="SCN46729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="16561" checksum="DCA785A9339D8D6A" modified="2016-11-30" version="1">MRILSIIIISVSILLSTGCSKGSQINGRSFKTALRSVKMLKDRLPQEQRVAFELSFWAIRDQYKNNISEFLDQVDGKSPEALIESGKAIFEKRKQEGFKEYQQYATWDDMIRKYTQERMDQLSKKQKRDPRDKDNSVLYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMG9</accession>
    <name>A0A1D3RMG9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0125 protein BAZMOX_00299_5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00299_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0125 (RnfH) family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00460">
        <property type="entry name" value="UPF0125_RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005346">
        <property type="entry name" value="RnfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037021">
        <property type="entry name" value="RnfH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37483">
        <property type="entry name" value="PTHR37483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03658">
        <property type="entry name" value="Ub-RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="91" mass="10251" checksum="3E12F70B42CAC896" modified="2016-11-30" version="1">MEVEVAYATPEQQLILTVKVAVSCTVEQAIALSGIVSHFPEIDLTKNKVGIFSQICPLNQLLQENDRVEIYRDLALNPMEARRQRAIQQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI8</accession>
    <name>A0A1D3RMI8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ORF">BAZMOX_02473_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="FMJP01000366">
        <property type="protein sequence ID" value="SCN46915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="39"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="300"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="13"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="41"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="332"/>
            <end position="334"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="414"/>
            <end position="416"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="430" mass="46223" checksum="41634FDA1874CB09" modified="2016-11-30" version="1">MGKNVVVIGTQWGDEGKGKLVDLLTDQATAVVRFQGGHNAGHTLVIGDKTTVLHLVPSGVLREDVQCLIGNGVVLSPEALLKEIKILEAAGIPVRSRLLISEACALILPVHVAIDQAREKAKGAKAIGTTGRGIGPAYEDKIARRGIRAGDFLNIELFTEKLKELTAYHNFMLTEYYKVPAIDFDTMLAESLELAEQIRPMLIDVAEKLYTYQDNGDNLLFEGAQGALLDIDHGTYPFVTSSNTTAGGAATGTGVGPLDIDYVLGITKAYSTRVGNGPFPTELDDAYGEHLGVKGHEFGATTGRKRRTGWFDAVSMRKSAQINSLSGICLTKLDVLDGLDKIGICTAYKIGGKEVTVAPLGAENYEACVPVIEYMDGWQEITKGMTELDKLPSAARAYISRLEELVGVDITILSTGPERNETIVLTNPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK7</accession>
    <name>A0A1D3RMK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold-shock DNA-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_180737_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000363">
        <property type="protein sequence ID" value="SCN46910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="7286" checksum="07EF01E107315A42" modified="2016-11-30" version="1">MSTTTGTVKWFNESKGFGFIEQESGPDVFAHFSAISGSGFKTLAEGQRVEFTVTQGEKGPQAENIVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM3</accession>
    <name>A0A1D3RMM3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent protease subunit HslV</fullName>
            <ecNumber evidence="5">3.4.25.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hslV</name>
        <name evidence="6" type="ORF">BAZMOX_23179_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP-dependent cleavage of peptide bonds with broad specificity.</text>
            <dbReference type="EC" id="3.4.25.2"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Allosterically activated by HslU binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.2" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000358">
        <property type="protein sequence ID" value="SCN46904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01913">
        <property type="entry name" value="protease_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00248">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="PTHR32194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039093">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0888">Threonine protease</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="6"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="182" mass="19836" checksum="8C20B876250E4323" modified="2016-11-30" version="1">MDFRGTTILSVRRGDKVVIGGDGQVTLGNTVMKGNARKVRRLYHDKVIAGFAGATADAFTLFEHFEGKLEKHHGNLTRAAVEMAKDWRTERSLRKLEALLSIADSKSSLIISGNGDVIEPEFNLIAIGSGGPFAQSAARALLESTDLSAREIVEKSLNIAADICIYTNHNLRIEELDAEPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM8</accession>
    <name>A0A1D3RMM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chorismate--pyruvate lyase</fullName>
            <ecNumber evidence="1">4.1.3.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00824_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.1.3.40" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000397">
        <property type="protein sequence ID" value="SCN46955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008813">
        <property type="term" value="F:chorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01632">
        <property type="entry name" value="UbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007440">
        <property type="entry name" value="Chorismate--pyruvate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38683">
        <property type="entry name" value="PTHR38683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04345">
        <property type="entry name" value="Chor_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="186" mass="21743" checksum="D0B602F9FF6440B4" modified="2016-11-30" version="1">MHNISSLYSKEPTWFCNRLRSRLNIPNNAASWVFEAGSITQRLRNYYGQHVRVQVLNNTWQRSFISESRLLKLPQAKYSLTREVLLLVDDTPLVLARTILPKRTIQSAQHNLSHLGSRPLGEVIFSYPKLERLALEISHVSPRAWHPEIQQLAQIQQPLWGRRTIYAIHHHPMLVSEFFLPEILNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN1</accession>
    <name>A0A1D3RMN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine desulfurase</fullName>
            <ecNumber evidence="2">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_09258_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.8.1.7" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000234">
        <property type="protein sequence ID" value="SCN46717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="1">
        <location>
            <begin position="15"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="373" mass="41863" checksum="F8AD63EA4D32CD82" modified="2016-11-30" version="1">MNHPEFPLSPELIHLNHAAVAPWPKRTSIAVKNFAEQNAQYGSSFYIDWLKKETKLRRQLQILLNAPSQNDIALVKNTSEALSFVAYGLDWQVSDNIVSSNEEFPSNRIVWQSLANQGVEFREANLSSKKSPEDALFALVDRNTRLITISSIQFASGLRLDIAKIGQFCKDHNILFCIDAIQSLGAVQFDVQTCQADFVMADGHKWMLGPEGLGVFYSSATAREKLKLTQYGWHMMENIHNYENKPWKIHPTAQRFECGSPNMLGIHALSASLSLLLEIGMSEVERKILANAQHLMSAIQSRADLELLTQKNAQLQSGIVVFKHKTIANETLYSHLQANHVICAIRGGGIRFSAHFYNTKDNLDRALALIPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN3</accession>
    <name>A0A1D3RMN3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HflC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_02473_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">HflC and HflK could regulate a protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the band 7/mec-2 family. HflC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000366">
        <property type="protein sequence ID" value="SCN46914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052547">
        <property type="term" value="P:regulation of peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03405">
        <property type="entry name" value="SPFH_HflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010200">
        <property type="entry name" value="HflC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42911">
        <property type="entry name" value="PTHR42911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005651">
        <property type="entry name" value="HflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01932">
        <property type="entry name" value="hflC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR005651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="286" mass="32398" checksum="A638959A1F5DB1E7" modified="2016-11-30" version="1">MLSNKILVGLAAVVSLGMMSVFTVSETEKAIKFKFGEIVESDYKPGLHFKMPFINNVKKFDARLLTLDSSPERFLTAEKKNVIVDSFVKWRIGDVNTFYTSVAGDIYQANVRLDQIIKDAFRSEFSKRDIKQLVSTDRSAVREALIANTTKIAATLGIEIIDVQVKRIDLPSEVSQSVYRRMEAERARVAREFRSQGSEAAERVRANADKQKEIILANAFRDAEVIKGQGDATASDIYAKAYGQDTEFYAFYRSMAAYKKTFTKNSANIMVTEPDSDFFKYFKKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN6</accession>
    <name>A0A1D3RMN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_60068_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000407">
        <property type="protein sequence ID" value="SCN46961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="187" mass="20802" checksum="7606C443F9B87B67" modified="2016-11-30" version="1">MNLKHIFFIIAIQFLTLNTVSANEEFQAANKEVGVFDGTILTIPAVNSKKQEGAYQDVKFKLLPDGKWELLDYKNRGMVDGITNVNISLTETFPVQGFLEVSGTHMSGCGSIEKVRHQLVGNTFIVSVDDIPYPSKPLTNDDWLVCPSYFPSFSTTISLPLYGLKAGKYKYIVNDEFSGVFELSSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP6</accession>
    <name>A0A1D3RMP6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_32770_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000367">
        <property type="protein sequence ID" value="SCN46916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004546">
        <property type="entry name" value="Restrct_endonuc_T1M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00497">
        <property type="entry name" value="hsdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="9"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="178"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="535" mass="60695" checksum="EE855E01B8B8F43F" modified="2016-11-30" version="1">MTEHDQKELGKTLWGIADQLRGAMNADDFRDYMLSFLFLRYLSDNFEASAKKELGADYPKLEDDDKRAPLSLWYEQNTDDVAAFEKQMRRKVHYVIEPQHLWSSVAELARTQHDDLLLTLQQGFKYIENESFENNFQGLFSEINLDSEKLGKNYSDRNAKLCTIITKIAEGIADFSSDSDVLGDAYEYLIGQFAAGSGKKAGEFYTPQQLSTILSEIVTLDSQEPATGKKKKLNKILDFACGSGSLLLNVRNQLGSHGIGKIYGQEKNITTYNLARMNMLLHGVKDSEFEIHHGDSLLNDWDLLNEMNPAKKLECDAVVANPPFSYRWEPTEALGEDFRFKSYGLAPKSAADFAFLLHGFHFLGDEGTMAIILPHGVLFRGGAEARIRTKLLKDNNIDTVIGLPANLFFSTGIPVCILVLKKCKKFDDVLFINASEYFEKGKRQNRLLPEHIVKIIDTYQYRKEEQRYSRKILMKEIDKNDYNLNISRYVSTAKPEPIIDIQAVNADLINLEKKAQSAAKTHNKFLEELGLPPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS9</accession>
    <name>A0A1D3RMS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01638_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000388">
        <property type="protein sequence ID" value="SCN46946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="128" mass="14646" checksum="1F6B6F3F3AC95BC2" modified="2016-11-30" version="1">MRQYCAKSGKSISSVTNAAIRAYLDETTDTKLLFRRLDKHTRALAKANRDIQLMAEALSVFVKLWFAHTPRIPDNDKENAQRYAAQRYEQFCDYVATQISGGHYFVDDLVQDSPISEDELDAAREDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT1</accession>
    <name>A0A1D3RMT1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
            <ecNumber evidence="7">6.3.2.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Meso-diaminopimelate-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="12" type="ORF">BAZMOX_00289_4</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000434">
        <property type="protein sequence ID" value="SCN47001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="110"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="334"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="408"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="408"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="112"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="486" mass="53731" checksum="C3E270C6B230373B" modified="2016-11-30" version="1">MQLAELLAGVADVQQDVEVTHLALDSREVSVGGVFFALAGTQLHGMQFAHQVQQQGAVAIIYDPANDGELLAKPVIGLSLVAVEQLADKLGDLAARYYGWPTRQLHVVGITGTNGKTSCSQFLAQVLDNCGVIGTLGWGIYPNLQRTCNTTPDALMLQKIYAEFVEQNIKHVAMEVSSHGLEQGRVNAIYFSGAVFNNLSRDHLDYHGSLEAYFQAKLRLVQWPDLQYAVVNLDDTYAERVLAAISEQVPVFTYSMQDKVHNKDTSIQVRNIQYSLLGVECDVFWQAEQHKLKIALLGDFNLQNCLSVLAVLLAMGKPLGECLQSMQTIKPIIGRMECFTADTGKPMVVVDYAHTPDALEKVLMTLRWHCVAQLTVVFGCGGDRDKGKRAQMGRIAETLADRVIITDDNPRFEEGQTIIDEIIADLSMEKVCVINDRKSAIQHSILMSSDRDIVLIAGKGHENYQEIKGVQLPFSDREITQELLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMU0</accession>
    <name>A0A1D3RMU0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_05516_1</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000279">
        <property type="protein sequence ID" value="SCN46777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017232">
        <property type="entry name" value="NtrY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045671">
        <property type="entry name" value="NtrY-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19312">
        <property type="entry name" value="NtrY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037532">
        <property type="entry name" value="STHK_NtrY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="290"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="486"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN46777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="706" mass="78691" checksum="C957E3EBE24C9B22" modified="2016-11-30" version="1">MLIVLSFIILSLQLMSSAIQDTSQLSDMYTWLLLSNALGTVILLLLVGFNVFSLARRLKRREAGSRLTTRIVLLFIVLSLVPAGVVFYFSMQFLHQSIDSWFSVELDGAMEDSLELSRASLDQRLRWDLKQSQGLAETLASKSDAEISLELDHFREVAGVNEVSLLSKKGKIISFSGLNPSDILPSLPVSPLFLQVQQGNDYVALASVNGELVVQTVVAIKPKNMRYLQVIYPVPERINDLTDSVEFAYVRFQEMMYLRHSLKVSFSLVLSLVLLMSLLAAISAAFVSVRSIIAPIRDLVRGTQAVASGFYGQLLPVKRLDDLGFLVESFNEMVMQISHAQDEARKNAQEIERQRAYLETLLTSLTSGVLSFDSSLNIRTANQAASIILHVQVMRYYGQDLMKLAQGRPDLMGLAEVVQPLLEKSFDIWQRNVVVDGPEGRKELLCQGAPLFSTEGGYIGAVVVFDDITDLIRAQKNAAWSEVARRLAHEIKNPLTPIQLSAERLQHKLASKLEVEDAEMLQRSTRTIVQQVEAMKQMVNAFAEYARPVHNKAEKLDLLALVQEVIVLYSSDPHVRFDLQVKGRISLIKADAVNIRQVLHNLFKNALEAMGGKGDVTVKLESVQQYNSEFVRLAIYDTGCGIDIKQAKQIFEPYVTSKEKGTGLGLAIVKKVIEEMGGSIRLDSKYTQGAGFIMQFPAVFDRQGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY0</accession>
    <name>A0A1D3RMY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar regulatory protein FleQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_85891_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000462">
        <property type="protein sequence ID" value="SCN47040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="27"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="366" mass="40968" checksum="76E48DC500A0BA4C" modified="2016-11-30" version="1">MDSLQALQHKQQNHVKSAPRSPDNKGLAGSSEAIKQVRFLIDQVADSDATVLILGESGTGKEVVARALHRASSRHNHAFVPVNCGAIPAELLESELFGHEKGAFTGALATRQGRFEMAEGGTLFLDEIGDMPMPMQVKLLRVLQERSFERVGSNKTIHCDVRVISATHRDIEQAIVENLFREDLFYRLNVFPIEMPALRERVEDIPLLIKELSSRLKKNKRATVTLTPDAVNILMQHTWPGNVRELANLIERVAIIKPNGLVDVADLPAKFREFSVSDEIVVEQAPENFLELAQEMEDKLEQAVVQKVFSAQLPEEGMDLKEYLNEVEISLIKQALDECNGVVAHAAKLLNMRRTTLVEKLKKFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN04</accession>
    <name>A0A1D3RN04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_39746_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000485">
        <property type="protein sequence ID" value="SCN47071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="125" mass="13620" checksum="D215141442D66015" modified="2016-11-30" version="1">MNSTQKLMGAVAAVFIIGFLMVGSNKDQSNESKEAAAMIRAVAAMQTMATSKCPTAIKNATGDTVYFATSTDTDKQTYVTMTWDASKTDDKYSFKKAECTLHLTLGGISKLVIDDKTIIEKKVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN05</accession>
    <name>A0A1D3RN05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04316_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000451">
        <property type="protein sequence ID" value="SCN47026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="4990" checksum="9A29DB3D239B3D03" modified="2016-11-30" version="1">MSNGSVKIALLLWWLGMAENLVVTHFFKTGKGSLAKTTKRIKLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN38</accession>
    <name>A0A1D3RN38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II restriction enzyme eco47ii</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04389_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000477">
        <property type="protein sequence ID" value="SCN47056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019057">
        <property type="entry name" value="Restrct_endonuc_II_Eco47II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09553">
        <property type="entry name" value="RE_Eco47II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="247" mass="28723" checksum="C2A78DCC025EDFDD" modified="2016-11-30" version="1">MRNYGLSFISNEDLYNHTKDTVEKYRFQVDLAKFNKNLIDPIKLTFDSKVYDRNIQSVIESEIVRQMDKSNTNHIGYFHQNIFNHIGDGWSVPKNGYDIVNLGEHYYVEMKNKHNTMNSSSSQKTYMRMQHTILHTSNATCILVEVIARNSQNVVWNVSLDGNPVSNENIRRVSIDKFYELVTGKRTAFKDLCEQLPKVIEDIVNDIELDVESNTVFTELEKISPNLLKSLYLLSFKKYEGFGDFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN41</accession>
    <name>A0A1D3RN41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_28918_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000410">
        <property type="protein sequence ID" value="SCN46969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4269" checksum="D81E366BB2078A90" modified="2016-11-30" version="1">MHFGLANFPVAYCGLKIITSLALRFPDFQRMNGIKKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN66</accession>
    <name>A0A1D3RN66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_402054_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000496">
        <property type="protein sequence ID" value="SCN47086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="26"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="143" mass="16308" checksum="C1656C7430768486" modified="2016-11-30" version="1">MLRSIVGIRYAPAIAAKAHSQKRNTNRSWRMDETYIKVKGKWVYLYRAVDSHGDTLDFMLSERRDEDAATAFFKQAINNNGLPDKVVMDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIIEQDHRFIKKITKPMNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN88</accession>
    <name>A0A1D3RN88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_28918_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000410">
        <property type="protein sequence ID" value="SCN46968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021339">
        <property type="entry name" value="DUF2956"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11169">
        <property type="entry name" value="DUF2956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="115" mass="13201" checksum="3A16C31366E13320" modified="2016-11-30" version="1">MSRYSKKTQTSPETQEEALKVAKATQRPGQTKEQTKLIAQGIQKGIELYKKQQKERSRELNKKLKKVSGRLSQLNAPEIEEGGVEPEFIYRQHWLPWLLLGISWAGFVAFVLFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN95</accession>
    <name>A0A1D3RN95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Exodeoxyribonuclease V gamma chain ## RecC</fullName>
            <ecNumber evidence="5">3.1.11.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_02209_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.11.5" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000557">
        <property type="protein sequence ID" value="SCN47160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041500">
        <property type="entry name" value="RecC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17946">
        <property type="entry name" value="RecC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecC_C" evidence="4">
        <location>
            <begin position="65"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="348" mass="40239" checksum="95A258A8C2F7CA3C" modified="2016-11-30" version="1">MHSHYQLTDLVIKHPLQSFSSRYFSNTPDLISYNQTDLATAKALKQYKPTNEPWWQKELAHEEQEVLEISDLFAYFRHPQKYFLQHGLNIRFAQIKGEEPEREPFDLEDSYRINHQWIEAKLHGRNLSLEKLKAQGRWLSGELGKVAFEKKEQEIDQFVEKIHAKEAGTALDPLAIDLNMGSVRLVGSLANTYSHASLFYRYAPIKGKDFVIAWLQHLIINREREHITHLVSQDDFISFLPEHIQGNELEQFIAYYQAGGNQPEAFFTEAAFSYAKQQANLNKPNARSSKSAIEAAKETLNKSLEQSYEPELKLLYKNLADVDTLLNADFEHYSNTLLLAAWEATHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN99</accession>
    <name>A0A1D3RN99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplO</name>
        <name evidence="8" type="ORF">BAZMOX_28573_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000385">
        <property type="protein sequence ID" value="SCN46937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="7">
        <location>
            <begin position="28"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="144" mass="15304" checksum="FFBC7C1B507F2BCF" modified="2016-11-30" version="1">MYLNTIKPAEGSKKVRKRVGRGIGSTLGKTCGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKVGFTARKSKFTSEVRLNEIAKLSLAVVTLDDLIKSNIVPAFTKVVKVIKSGEITSAVTLKGLKVTVGAKALIEAAGGTIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC1</accession>
    <name>A0A1D3RNC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_82608_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000562">
        <property type="protein sequence ID" value="SCN47163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="53" mass="6015" checksum="07C4160D2D163D50" modified="2016-11-30" version="1">MVTKLLSTPIAEKKSSHEIREFTYSHGPVAMIGESEERPVFRHNYPAKAINCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE0</accession>
    <name>A0A1D3RNE0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_04671_4</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecG family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000446">
        <property type="protein sequence ID" value="SCN47018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34182">
        <property type="entry name" value="PTHR34182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="118" mass="11862" checksum="5319760EC745EE0F" modified="2016-11-30" version="1">MVVGLAVIGLVLIQHGKGADAGAAFGSGSSGTVFGAQGSASFLSRTTGVLATVFFSTSLALAVLSGNTGNDADIMDAPVIDPIAAEVPKIESEQQVVNEPALTEDELPVIVDEPIIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE6</accession>
    <name>A0A1D3RNE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyruvate dehydrogenase E1 component</fullName>
            <ecNumber evidence="1">1.2.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_165241_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.2.4.1" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000566">
        <property type="protein sequence ID" value="SCN47174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004660">
        <property type="entry name" value="PDH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825:SF3">
        <property type="entry name" value="PTHR43825:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="100" mass="11244" checksum="9017D97F32944639" modified="2016-11-30" version="1">MWQMHSKADIPVIAATDYIRAFAEQIRPYISAPYTVLGTDGFGRSDTRANLRSFFEVDRYHVTIAALKALVDKGEFEPAKVDIAIAKYNIDPEAIAPWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF3</accession>
    <name>A0A1D3RNF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tellurium resistance protein TerD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_58184_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000606">
        <property type="protein sequence ID" value="SCN47235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06974">
        <property type="entry name" value="TerD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003325">
        <property type="entry name" value="TerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02342">
        <property type="entry name" value="TerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerD" evidence="1">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="191" mass="20182" checksum="458A916BAA1A273B" modified="2016-11-30" version="1">MAVSLSKGGNVNLSKEAPGLTKVAVGLGWDNRATDGADFDLDAVAFLLGADGKVSADADFIFYNNLKSTCGSVQHMGDNTTGEGDGDDEVVEITLSNVPTTIQRIVVAVTIHDAETRKQNFGQVSNAFMRVVNADNNNEIARYDLSEDASTETAMIFGELYRHNGDWKFKAVGQGFVGGLGPLAASFGVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG6</accession>
    <name>A0A1D3RNG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_179333_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000598">
        <property type="protein sequence ID" value="SCN47230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="60" mass="6933" checksum="B7BF0F73E78BCDA9" modified="2016-11-30" version="1">MPEDKALFAFTNACDRTLRTYLIRVAGKLLTGNNQLRVRTPADPLYPQEWDDWVKLELPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH1</accession>
    <name>A0A1D3RNH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Programmed cell death toxin MazF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_179333_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000598">
        <property type="protein sequence ID" value="SCN47231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="119" mass="13169" checksum="D6D4B36E425F0068" modified="2016-11-30" version="1">MNYIPDRNDLVLLDFDPTKGKEIGKYRPALVLSSKAYSKATGLLICCPISTSIRNTPTEVPITNLDKPSVVASSLIQTLDYKSRSVKLISQAESGVFEEVLIRLIPLITGDEYLNKLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI4</accession>
    <name>A0A1D3RNI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Relaxosome protein TraY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_161992_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TraY family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000483">
        <property type="protein sequence ID" value="SCN47068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008876">
        <property type="entry name" value="TraY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05509">
        <property type="entry name" value="TraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="76" mass="8725" checksum="651F20CEE92EEB62" modified="2016-11-30" version="1">MSAVSLRLPNEISERLEHLSKETGRTKTFYMIQAIKEHLDDLEGLYLAEQRLIENRAGRSKTYTLNEVECDLGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI6</accession>
    <name>A0A1D3RNI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_349680_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000585">
        <property type="protein sequence ID" value="SCN47214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4302" checksum="5DEC19068D8C180B" modified="2016-11-30" version="1">MRKILEASFAAASAPYLESRKTNSRCKAFAENQGNGAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI9</accession>
    <name>A0A1D3RNI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_14960_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000524">
        <property type="protein sequence ID" value="SCN47119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="54" mass="6189" checksum="C45A0638E4053DB0" modified="2016-11-30" version="1">MSGKELDDMTLEKIIKLILQDVLCTILIVVKLFHQGAIEVTQSSTCHDIVYQWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL7</accession>
    <name>A0A1D3RNL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HigB toxin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_72607_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000551">
        <property type="protein sequence ID" value="SCN47149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007711">
        <property type="entry name" value="HigB-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40266">
        <property type="entry name" value="PTHR40266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05015">
        <property type="entry name" value="HigB-like_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="92" mass="10692" checksum="E89D1B669F70E853" modified="2016-11-30" version="1">MIKNFKHKGLKKFFEKGSLSGIQAKHADRLRDRLAFLDAAVFIEDMAKPGYNLHELIGNLKGRWSIVVSGNWRITFEFKDGDAYIVDYEDYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN2</accession>
    <name>A0A1D3RNN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_06368_2</name>
        <name evidence="1" type="ORF">BAZMOX_359617_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000346">
        <property type="protein sequence ID" value="SCN46882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000636">
        <property type="protein sequence ID" value="SCN47291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="7838" checksum="FCE95F1A5C2B201A" modified="2016-11-30" version="1">MKAKPTRKELTPKEQVIKEAMKIDSGETVTMTFKVPKELQQGYKMEALKSGESMTDAFIKHMKEYIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR8</accession>
    <name>A0A1D3RNR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FIG003879: Predicted amidohydrolase / Omega amidase (Nit2 homolog)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_01495_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000666">
        <property type="protein sequence ID" value="SCN47322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="265" mass="29296" checksum="09978E262FCADF6A" modified="2016-11-30" version="1">MASSPNINSNLLEAERLITDAVAAGAKLVALPENFALMGQDEFDKIKQKEQNGLGPIQDFLAHTAKKYAVWIVAGTIPIADPDNENKVMAACLVYNDLGECIARYDKIHLFDVQVPESKEVYRESDGISKGHKPLVIDTPFGKIGIAVCYDLRFPELFRVMQEQGMEILIIPSAFTAKTGAAHWELLLRARAVENLCYVIAPNQGGFHVNGRQTYGHSMIIDPWGTVLDCFKTNAGFAAADLDLARLHKTRTSFPVLQHRQIACK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS7</accession>
    <name>A0A1D3RNS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphomannomutase</fullName>
            <ecNumber evidence="3">5.4.2.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_02217_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000520">
        <property type="protein sequence ID" value="SCN47117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="2">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="179" mass="19324" checksum="260882875BF7BD98" modified="2016-11-30" version="1">MKNKVKFGTSGIRGLVSDMTDKVCYAYTLSFLHYLQSIDAIQVGQAVGVGGDLRKSTPRIMNAVAAAVVDAGYTVVNCGLLPTPAIALYGIAHKIATVMVTGSHIPEDRNGIKFNKPDGEVLKDDEQGILAQNPVLNDALFDGKESLLASDYLPAVNTTAEQQYIARYLDFFPENAWQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT1</accession>
    <name>A0A1D3RNT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_10702_3</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000679">
        <property type="protein sequence ID" value="SCN47341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="72" mass="8037" checksum="F943ED36B3309EEC" modified="2016-11-30" version="1">MLGGAVAVTWYIVYRLFKISSLSALVASVLAPVYVYFIMGMQPLVYVAAHISVILIWRHKGNIQRLLAGEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU9</accession>
    <name>A0A1D3RNU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Conjugative transfer protein TrbI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_16045_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrbI/VirB10 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000715">
        <property type="protein sequence ID" value="SCN47395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16429">
        <property type="entry name" value="VirB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005498">
        <property type="entry name" value="T4SS_VirB10/TraB/TrbI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042217">
        <property type="entry name" value="T4SS_VirB10/TrbI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03743">
        <property type="entry name" value="TrbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="168"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="429" mass="46772" checksum="7E65F731A8C37EB9" modified="2016-11-30" version="1">MSETDKISSDSASLRMSTAQPRRLKQGPIIALVFAAIGIIIIAFAVAMLSEPDNVGVAEDNLVPADDNRLPGFVKTGPKNYSEIPRPVPKLGPALEGDMGHVGVVAKTTTFKRPVAPAKRELTPEEQRLIAERIQAMKADVFFPGFNEKREQDLSEKNQAELHSNLAERRSALRGNRPTYSPDLSALKQKTEWDSQNKQSDKSSFLEKYSKDSPNAYLKATITHPVSPYEVKAGTIIPTTLITGINSDLPGQIVGQVRENVFDTVTGNYLLIPQGTRLVGQYDSGVAFGQERVLVVWHRLIMPNGASINLEGMPGVDLTGYAGFKDKVDRHWLQLAGGVILSSIMSAAVTSSQGSQTGFSPTLSQGFVSSIGQDINRTGQKIVDKMLNRQPTITIAPGFAVNVFVNKDMILEPYNANRGMRFDTNFATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW0</accession>
    <name>A0A1D3RNW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_53206_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000596">
        <property type="protein sequence ID" value="SCN47229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_38" evidence="1">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="213" mass="24380" checksum="34AD0219A1F1EA7B" modified="2016-11-30" version="1">MHFGLANFPVAYCGLKIITSLSLRFPGFQRKKYSQLTDVQRYQIEALKKAEKDQKTIASIIGVSASTISRELKRNTGQRGYRPKQAHIKALKRRKESAKVIKMTEGVITIIETKIQLDWSPEQVSGWLNKGHDILSISHERIYQHVREDKRQGGALYKPLRYSHKKRKKQYGGKDKRGQIKNRVSIDERPEIVVERGESAIAVGPVVLSESER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP01</accession>
    <name>A0A1D3RP01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type I restriction-modification system, specificity subunit S</fullName>
            <ecNumber evidence="5">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_18693_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000724">
        <property type="protein sequence ID" value="SCN47403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="24"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="281"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="437" mass="49023" checksum="935A6ECEF1381C47" modified="2016-11-30" version="1">MSKQVTKTCVPKLRFPEFWGTGMWEEKPLGEIASFFKGKGLPKSAILPEGKNPCVHYGELFTQYPEVIDAIKSHTDLNTNCFFSVRNDVLMPTSDVTPSGLAKSCCINLDGVILGGDILVIRTDNTSISGEYLARLIRYFEQKVLQLVTGSTVFHLYASSLEKLTIFLPSLIKEQKKIADCLSSIDELITAHSQKIEALKAHKKGLMQQLFPSDGETVPKLRFPEFRDAGEWEEIKLINVADKKIKWSFIGGPFGSNLKSSDYVTEGIRIIQLQNIGDAEFKDDYKIFTSEEKANELLSNNIYPDEIILSKMGDPVGRACLIPSTHKRYVMCSDGIRLIVDQENFSKYFIYTLINSIEFRALVEKTATGSTRKRIGLSDLKNLPMIVPKTKEEQQKIADCLSFIDDLITAQAKKIDSLKAHKKGLMQQLFPSTEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP04</accession>
    <name>A0A1D3RP04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MCP-DOMAIN SIGNAL TRANSDUCTION PROTEIN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_295926_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000629">
        <property type="protein sequence ID" value="SCN47269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="53"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="210" mass="23877" checksum="95DFFD5D8BF7A536" modified="2016-11-30" version="1">MAIQIFLTIESLITQGIELAHIISIFIAFIIVFLFFKQSNRELHIIKSMFKLANSIEKGKLEYRITHIDPKSELGPIAWNFNEALDQIEAYMREVNTCFQSAENKEFYRKAQVMGIKGDFSAGLEKVDVSLGMMEQNHFNTVRDELFSQLGQMKTENLLNSLHRTQDDLSRIANEMEQVEGITKHSSDISSASQASLGTVIDQLTQIITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP14</accession>
    <name>A0A1D3RP14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multimodular transpeptidase-transglycosylase</fullName>
            <ecNumber evidence="3">2.4.1.129</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_04812_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.4.1.129" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000707">
        <property type="protein sequence ID" value="SCN47386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031376">
        <property type="entry name" value="PCB_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17092">
        <property type="entry name" value="PCB_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PCB_OB" evidence="2">
        <location>
            <begin position="96"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="548" mass="61611" checksum="FD5F0FF089F31E86" modified="2016-11-30" version="1">MKRMLDLEYINQQDYDTAIQAPITASTYTTQRELYAPYIAEMVRNEIIHLYGEEVAYSAGLKVYTTIKSDLQNTAVSALRNNLHNYAERHSYQVNKAQKQTLKASDKIGDTVPATVLEINKKQLTVQTQEKEVITLYWKDSPWSTKYDPHNEKTQSISSFLDIIQLNDTIRLRKVKAKWRLAQIPQAESAFIALDPNSGAILALSGGYAYFNNKYNRVTQAKRQPGSGFKPIIYTTALEHGYTAASMINDAPILDTNNSTQESEWRPENYSHKFYGPTSIRTALRKSRNLISVRLLRSIGIPAVTKTALRFGFNKEQLPQKLSLALGSGYASPLQMARMYAVFANGGFLITPFFIERIESSTGEILFQAEPLTACTNCVAKNPPQIITPQINFIMNTLLRDVVQRGTATKAKSLQRTDLAGKTGTTNDQKDAWFNGFTPHIVGIAWVGRDNSQSLGRFETGGKAALPLWVDFMRYALKDKAEEELVMPEGISKVLIDTEEGLLAREESPTSTWEYFRTKFVPTQYVPFTPEITNNTTGEEQATPEALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP27</accession>
    <name>A0A1D3RP27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_01548_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000761">
        <property type="protein sequence ID" value="SCN47450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="364" mass="40050" checksum="BDE22DCD167F3962" modified="2016-11-30" version="1">MFSTSLANAGIDLVSPITRVLGSYWYVLGTEVSHFEGEFAKYNDVKNCVSVANGTDALELGLRSLDIKAGEPVIVTANAGFYSSTAIHLIGAKPVYVDINPTTHTLCVDALQKRLEVDKPKAIIVTHLYGQLADIERIVEIASKAGIPVIEDCAQSHGAMRNGKRAGSFGTIGCFSFYPTKNLGALGDGGAVITNDTAIAEKLRQYRQYGWSSKYCVDLPGGRNSRLDEMHAAILREKLTHLERQNTERRGIARKYNKAFEKSPLICPTSLDDDYVAHLYVLQISKRDEFRSFLNEQGIMTDTHYPIPDHLQKAYSCEQKIGSLPLTEAACDKVVSLPCFPGMEDVDVERVISAVTLYFKSTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP45</accession>
    <name>A0A1D3RP45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_326077_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000771">
        <property type="protein sequence ID" value="SCN47461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="3899" checksum="B326173432C70B50" modified="2016-11-30" version="1">MGEMASTLGHNEQRESLFLQKLVLGIPAQAGSVASID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP48</accession>
    <name>A0A1D3RP48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02905_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000594">
        <property type="protein sequence ID" value="SCN47227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4164" checksum="76041AC8E163C23C" modified="2016-11-30" version="1">MEAIMKKILSALAITLMLVGATGCMDDPDGSQQHTTRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP67</accession>
    <name>A0A1D3RP67_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MEMO1 family protein BAZMOX_81706_1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_81706_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the MEMO1 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000607">
        <property type="protein sequence ID" value="SCN47237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PTHR11060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="261" mass="28493" checksum="0795A79DF82F3435" modified="2016-11-30" version="1">MQSIRPPAVAGSFYPDNPHELRAMLAEYLEQAEPSVTAPKAMIVPHAGYIYSGVCAAKAYARLAPKHAMIKRVVLLGPSHHVAFTGLALSSADVFNTPLGDIPLDKKAIDSLLQFPFVAYLDQAHALEHSLEVQLPFLQMTLDDFSLVPIVVGDCPAEQIALVLALFYDQSNTLIVISSDLSHFHDYATAQRLDQETSEKIEKLDYQHLDYDSACGRVPVSGLLALAKKKSLQIKTIDLRNSGDTAGDKSRVIGYGAYVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP77</accession>
    <name>A0A1D3RP77_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RCK N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00950_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000793">
        <property type="protein sequence ID" value="SCN47501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="116"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="396" mass="44175" checksum="C0FB6E74D0F088F5" modified="2016-11-30" version="1">MQMLVSRDSLLEAGVRSANCQAVVCITNNEEVNLKISAIVRLLNPKTRIITMSKVDDFEETLSTLGGEVHIVDPFKTFARVLNASINNTAFYALNNWLVGDKCATLDSYVQPPLGGWIICGYGRMGLEANRVLTKNGVKTAVIDPHSRRKEEEIDTYVIGHVNAKTLSQAGIHEAVGLLAADADDGHNLGTLLNARCLNSNLFTIVRQNSHENEVAFSEANADMIMQPTLVTARKILLLLIAPLLKPFFRYLLAKKSGREEILKNLLVLLREKIGNQKPCLVTIDFNSEKSSAVIQALDEGEEVLLGHIISDPRNRDVELDLAPFVIKSCGKEIVLPAKDYKILEGDQLLFCGTSTSKYLLKSSINSEYTLYYLRTGQYKPMGYFMQWYERRFSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA0</accession>
    <name>A0A1D3RPA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Squalene--hopene cyclase</fullName>
            <ecNumber evidence="5">5.4.99.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_00594_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis; hopanoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene cyclase/mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00337"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051007">
        <property type="term" value="F:squalene-hopene cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016104">
        <property type="term" value="P:triterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002365">
        <property type="entry name" value="Terpene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="PTHR11764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01074">
        <property type="entry name" value="TERPENE_SYNTHASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SQHop_cyclase_C" evidence="4">
        <location>
            <begin position="19"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="201" mass="23042" checksum="FC9F209F5FAB37AC" modified="2016-11-30" version="1">MIDYSWTECSAACVVALLEILELYPDYKRSEIEHAITDGLKFIVKQQKMDGSWYGGWAVCFTYATWFGIEALVQGKDYIDAQLRTNCINKACDFLLSKQMTDGGWGETYESCAKMVYSQAETSQVVNTAWALLALQAAKSPEKTALQRGINLLLDRQLENGDWAQENISGVFNYNCMITYSAYRNIFPIWALNRFYQHKHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA8</accession>
    <name>A0A1D3RPA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transamidase GatB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_10702_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000679">
        <property type="protein sequence ID" value="SCN47338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="149" mass="16692" checksum="34AC933C98B3C59D" modified="2016-11-30" version="1">MTTMQSRLKDEMKQAMRDKEKSRLGTIRLIMAAIKQIEVDQRIVLDDEQVIATLDKMLKQRRESIRQYRDAGREDLAEVEEAEIVVIQDFLPQALTEEEIVAMVESAIADCSASSIKDMGKVMALLKPAMLGRADISVVGKKIKTALGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA9</accession>
    <name>A0A1D3RPA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Conserved hypothetical WD domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_32698_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000791">
        <property type="protein sequence ID" value="SCN47494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="191"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="316" mass="35339" checksum="51C30496982214D5" modified="2016-11-30" version="1">MNKCFLAPLLCALLLGACDNTPKASRTYKLVPEGVFSASLSKNLALTSSTTRGNASLWQLKPKQLLHTWQHTDEKNGILFTAISDNEQYALTAEKESLAWWRIADGALMNVWYLPNINAITLSKDGQFALIGLADKAIYYSLQHGQTRYAFKHQSPVVKVDISASNQLAITGSSDKTAKLWDLNTGEEKFSWSHHSKLSTVAISPDDKYALTNEGLGTIRLWKTQTGKLYKQLGPKLITLSSAAFSDNSKYLVAGRVSQRIDLWNIRSGEIINYWRPKKDSFWKPTAATILALTFSANNRKIYSIASNGYLQLWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD9</accession>
    <name>A0A1D3RPD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Predicted signal transduction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04184_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000731">
        <property type="protein sequence ID" value="SCN47409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="8"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="267" mass="30042" checksum="DFABD4B15CD311DB" modified="2016-11-30" version="1">MQSDSLDLPTIPDVSFKIKKAINDSSANNNKIARVVQIDPSITARLIKISNSPLYRGRRKIESCPEALTRLGLQSSQQIITTFALKGVFNASSRVIRKKMHELWQHSSYVAAISAVLAHKTPGFDPDKAMLAGLIHDIGIVPILAYADKQPDILASPKDLTETVRKLRVEIGVQILRKWDFHEDFEDVIINSENWHRNNNEKADYADIVMISQLHSYIGKIDPKKMPKLDELPAYKKLVSGNLDVDLSINILDQAKDEINDIQKLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF1</accession>
    <name>A0A1D3RPF1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_Tnp_IS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_315435_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000807">
        <property type="protein sequence ID" value="SCN47534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024431">
        <property type="entry name" value="InsA_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12759">
        <property type="entry name" value="HTH_Tnp_IS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_IS1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="66" mass="7542" checksum="F5481A7C1F777375" modified="2016-11-30" version="1">MLDYRYNACAPGIKEKVVEMAMNSSGIRETARVLKIDKNTVISILKRKEDSLVQVNPIFLSESRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG1</accession>
    <name>A0A1D3RPG1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmB</name>
        <name evidence="5" type="ORF">BAZMOX_16663_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000845">
        <property type="protein sequence ID" value="SCN47590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="78" mass="9181" checksum="C4D83A99AA463BED" modified="2016-11-30" version="1">MSKICQVTGKRPITGNNVSHAHNKTRRRFNPNLHHHRFWVESENRWVRLRLTAKGMRIIDKKGIDAVLADIRQRGEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH2</accession>
    <name>A0A1D3RPH2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Squalene monooxygenase</fullName>
            <ecNumber evidence="3">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_00594_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="PTHR10835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="8">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="SE" evidence="9">
        <location>
            <begin position="163"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="458" mass="51585" checksum="98E460B39D268A38" modified="2016-11-30" version="1">MHTTSEHNDLFDICIVGAGMAGATIATYLAPRGIKIALIDRDYAEKRRIVGELLQPGAVQTLKKMGLEHLLEGFDAQPIYGYALFNKDCEFSIEYNQDKSTNYRGVGLHNGRFLQKIREDALKQPSITQIHGTVSELIEDENHVVTGVKYKEKYTRELKTVNAKLTITSDGFFSSFRKDLTNNVKTVTSFFVGIILKDCELPYPHHGHVFLSAPTPFICYPISSTESRLLIDFPGDQAPKKEAVKHHIENNVIPFLPKEFRLCLDQALRENDYKIMPNHYMPAKPVLKKGVVLLGDALNMRHPITGGGLTAVFNDVYLLSTHLLAMPDFNDTKLIHEKVNLYYNDRYHANTNVNIMANALYGVMSNDLLKQSVFEYLRKGGDNSGGPISLLAGLNRNPTILIKHFFSVALLCLRNLFKAHKMSLTNAFYVIKDAFCIIVPLAINELRPSSFLKKNIHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH4</accession>
    <name>A0A1D3RPH4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquinol-cytochrome c reductase iron-sulfur subunit</fullName>
            <ecNumber evidence="6">7.1.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Rieske iron-sulfur protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BAZMOX_02140_2</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 19">The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000854">
        <property type="protein sequence ID" value="SCN47600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019470">
        <property type="entry name" value="Ubiq_cytC_Rdtase_Fe-S_su_TAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="PTHR10134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10399">
        <property type="entry name" value="UCR_Fe-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="21">
        <location>
            <begin position="84"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU004497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="SCN47600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="198" mass="21340" checksum="B4CE72703E1C7548" modified="2016-11-30" version="1">MSDQGVDRSKRQFLTTALTVVGAVGTGYIAVPFLSQMQPSTKAKAAGAPVEIDISKMETGQLIRAAWRGKPVWVLNRTPEVLEILATDTDKLADPNSLESNQPESSTNEFRSIKPEIFIAVGLCTHLGCSPTFRPEIAPNDLGEDWKGGFFCPCHGSGFDLAGRVFRGVPAPTNLDVPPHRYLSETRIIIGDESGADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ2</accession>
    <name>A0A1D3RPJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FIG001353: Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_124587_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000833">
        <property type="protein sequence ID" value="SCN47574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="46"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="142" mass="15800" checksum="0A7D0B8B11F6A52D" modified="2016-11-30" version="1">MQKIAHQHMGKGLSKTFVLIDAEQPTVIIAYMSLVVCEVLADDIPHQWKKKYPNRIPAAKLAKLAVSVEQQRKGYGETLLIDAMQKTLNVSQTIGLAGLFVDAKHQQVKAYYQQFGFLSLSEQLDNLFIPLSTIAKSLGNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ4</accession>
    <name>A0A1D3RPJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-glycerate 2-kinase</fullName>
            <ecNumber evidence="3">2.7.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00536_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.1.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000767">
        <property type="protein sequence ID" value="SCN47459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037035">
        <property type="entry name" value="GK-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038614">
        <property type="entry name" value="GK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007835">
        <property type="entry name" value="MOFRL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025286">
        <property type="entry name" value="MOFRL_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039760">
        <property type="entry name" value="MOFRL_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12227">
        <property type="entry name" value="PTHR12227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13660">
        <property type="entry name" value="DUF4147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05161">
        <property type="entry name" value="MOFRL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF4147" evidence="2">
        <location>
            <begin position="12"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="MOFRL" evidence="1">
        <location>
            <begin position="337"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="455" mass="48089" checksum="7DB1E7A5934613EF" modified="2016-11-30" version="1">MTQATNDLRQDALAIFQAGIQAADPYSAVKRCLQSDGEQLDIALDLDNRAKRSGNWQKIYVIAFGKAACSMAKAAQEIIPAQLLAQPILAITNYENVTELANIEILGANHPLPDQTGFVAAQRIAKIAQQAQQGELVLALVSGGGSALIPFPADGISLNEKIATTDLLLASGATINEINCVRKHLSQIKGGGLAKFTAPADLHALILSDVLGDKLSDIASGPTIADDTTFNDAIQVFKDKNIWHKITQNVQTHLENGAQGIISETAKTGDAIFNNTGHTLCGSNTISLQATSQMAQNLAYDLHLYSDQLSGEAKHIAEDLVIYAQALLSSGINKPNAILAGGETTVTITGTGLGGRNQEMALAFAIAAEKHQLNANWVFLSGGTDGRDGPTDAAGGIVDQQTIARMRNATIEPKQYLANNDAYHALQISEDLLITGATGTNVADLQILLIQPQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ6</accession>
    <name>A0A1D3RPJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Succinate dehydrogenase, cytochrome b556 subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_49357_0</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Membrane-anchoring subunit of succinate dehydrogenase (SDH).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="10">The heme is bound between the two transmembrane subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome b560 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000831">
        <property type="protein sequence ID" value="SCN47566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045281">
        <property type="term" value="C:succinate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000104">
        <property type="term" value="F:succinate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018495">
        <property type="entry name" value="Succ_DH_cyt_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000178">
        <property type="entry name" value="SDH_cyt_b560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02970">
        <property type="entry name" value="succ_dehyd_cytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01001">
        <property type="entry name" value="SDH_CYT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared with second transmembrane subunit</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000178-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="104" mass="11755" checksum="993753E511EDB1A6" modified="2016-11-30" version="1">MTHRMTGVLLTAGLLLFVVSLAMIQCGASSFNTMQAFIQLPLVELALWLMIYALFFHLCHGVRHLFWDSGETYDKLLMNYYIILELFGSVALTGLSFLFVQMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ8</accession>
    <name>A0A1D3RPJ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Riboflavin kinase</fullName>
            <ecNumber evidence="2">2.7.1.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_84223_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000693">
        <property type="protein sequence ID" value="SCN47367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="8">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="116" mass="12934" checksum="7FBE24A407DF606B" modified="2016-11-30" version="1">MVHGEKLGRKIGFPTANIQMLRKNTPIAGVFAVTMTGIAGKPVNGVANVGTRPTVDGGSKVLLETHLFNFDQDIYGKYVEVHFKHKIRNEMRFQSVEDLKRQIQLDTAQAKTLLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL4</accession>
    <name>A0A1D3RPL4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnc</name>
        <name evidence="10" type="ORF">BAZMOX_237812_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000850">
        <property type="protein sequence ID" value="SCN47594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="5"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="154"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="227" mass="25355" checksum="F62CC72B7D1751CB" modified="2016-11-30" version="1">MIKPPKILCKKLGLSFSQLELFTLALTHRSIGSKNNERLEFLGDSILGFVIAEALYNKFPHADEGILSRLRASLVNQTSLAELARKHKIGDYLILGSGELKSGGYRRDSILSDALEAIMGAIIKDQGIEACKAWILTLFAERLDGLSLDNWQKDPKTRLQEHMQARQIDIPKYKLISESGLAHEKTFQVECSVDLLKIKFIGVGASRKKAEQHAAELMLQEIAKEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL5</accession>
    <name>A0A1D3RPL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_134783_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000780">
        <property type="protein sequence ID" value="SCN47479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="109" mass="12303" checksum="B67B7D6DC4023F0A" modified="2016-11-30" version="1">MSSKTSKKNASMDALLNAAAEPEKETAQNEPVIEPVKRGKGRPKKAEGNRQQLPTYLPEPLYFEMLDYVNLKKRSDRQYSLNDLVLEGLDLWLASIGKPSISELIKENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM2</accession>
    <name>A0A1D3RPM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_133783_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000889">
        <property type="protein sequence ID" value="SCN47643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="71" mass="8563" checksum="4546481960886544" modified="2016-11-30" version="1">MKFEPLVFIRIANRNGIKLTRVEGGFMRVRGKYATWLPLLRKHKRQLMKYLDKDEAYRIQLDLFDDLPPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM3</accession>
    <name>A0A1D3RPM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_123298_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.7.8" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000860">
        <property type="protein sequence ID" value="SCN47604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="208"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="283" mass="30093" checksum="C21E3A810B856EEE" modified="2016-11-30" version="1">MPDMAEFPYTIRVVSEITESNGSSSMASVCGTSLALMDAGVPLKAPVAGIAMGLIKEGDAFAVLSDIVGDEDHLGDMDFKVAGSEKGITALQMDIKIDGITSEIMSNALDQAKAGRLHILGEMNKALSTTREEMSDFAPRIITFKIDPSKIREVIGKGGATIRGITEQTGATVDLTDEGVVNVASVDKAAGEAARKIIEEITAEVEVGKTYEGKVARLMDFGAFVTILPGKDGLVHISQITDEHVDKVSDKLKEGDVVKVKVLEIDRQGRVRLSMKEVGKAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM4</accession>
    <name>A0A1D3RPM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_07461_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000893">
        <property type="protein sequence ID" value="SCN47650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="209" mass="24174" checksum="3BFB2A7C42657C4C" modified="2016-11-30" version="1">MVQCGQRHFNQVENIDSDRTVVLAEITMASLTVGDRIDDADFLARVDMLNTQGYTVLISNYLRYFRLRQYFRRYTQQQLGMILGISNLDLIFREEYYNGLEGGILEAFAKLFPDNTRLYIYPIHSIEQDKLVTVDTFQPPKKLSHLYEHCKDNGYLVGLDNVDEGVLDINPHQVLLDIKKGRGEWETQVPESIAEMIINNRLFGFGSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP4</accession>
    <name>A0A1D3RPP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UPF0182 protein AF1421</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_10997_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000906">
        <property type="protein sequence ID" value="SCN47661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005372">
        <property type="entry name" value="UPF0182"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39344">
        <property type="entry name" value="PTHR39344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03699">
        <property type="entry name" value="UPF0182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="389" mass="43977" checksum="F73C6CED30CB4380" modified="2016-11-30" version="1">MADYPYALVPNSEVLNSSDKSAGDMKTDYQGTGGLALTSLFIKAIASAYFSDERIFFSVSINNETRLLVRRNILKRIRIIAPFLSLDNEPYPVLVKHKIYWVVDAYTTSGLYPLVEPVTLNKSAKQPFNYARNSVKIVVDAYNGSVAFYVVDGQDPLIKTYQRLYPGLFKNLEDAAPEIIKHFSYPKAWFALQMRLYARFHQADPDIFYQQSEALEFARMDEKPIEPYYLTIDIDEDADEQQKFILVSPLSPFGRENLDSIAIAGCLTVKHCNNHYQDDIYLYKFPQNMQVEGPAQISALMNQNPDISAQLTLWDQLGSRVIRGRMIIIPVEHSLLYIQPVYLAATSKQGFPSLAKVLVAMNRSTALADSVSLAFAALQEKLQPRGAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU8</accession>
    <name>A0A1D3RPU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="12" type="ORF">BAZMOX_04315_7</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000822">
        <property type="protein sequence ID" value="SCN47559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="208" mass="23528" checksum="A1520401BA4EB6BC" modified="2016-11-30" version="1">MGQKVHPTGIRLGIVKDFTSRWYANSKDYPVFLHQDLTVREYIQKKLAHASVSRIQINRPANNAHITIHTARPGIVIGKKGEDIDVLRKEVSKMMGIPVQVNVEEIRKPELDAKLVAESVAQQLEKRIMYRRAMKRAVTNSMRLGAEGIKINLGGRLNGAEIARSEWYREGRVPLHTLRADIDYGVAEANTTYGIIGIKVWIFKGEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW1</accession>
    <name>A0A1D3RPW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation elongation factor G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_24983_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000836">
        <property type="protein sequence ID" value="SCN47579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="8"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="123" mass="13856" checksum="7B36AC9081A453F0" modified="2016-11-30" version="1">MARITPIEKYRNIGIMAHIDAGKTTTTERILYYTGVSHKIGEVHDGSAVMDWMEQEQERGITITSAATTCFWSGMEGQFDKHRINIIDTPGHVDFTIEVERSLRVLDGVCAVFVRLVVLSRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX0</accession>
    <name>A0A1D3RPX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_30273_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001000">
        <property type="protein sequence ID" value="SCN47795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4770" checksum="733FAAC02C2807E0" modified="2016-11-30" version="1">MFYFVFSGYGRAYFSCTSAHTCTGDGTAMVTSNVLLCFQWLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX7</accession>
    <name>A0A1D3RPX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobalt-zinc-cadmium resistance protein CzcA Cation efflux system protein CusA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_113409_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000787">
        <property type="protein sequence ID" value="SCN47487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="251" mass="26883" checksum="8296745CF94DDFF2" modified="2016-11-30" version="1">MNSGLLISGPDGIKVPLAQIAKIEEIVGPRQITRENNQRFISIQANVIDRDIVSFVEEAQQVIDNKIKLPPGYFTTWGGQFRLQQEANKRLAIVIPVTLVIISLLLYSSFGSVKNAALILLNIPLALVGGVIALWISGQNLSVPASVGFIALFGIALENGMVLMTYLNQLVKQGMPIDEASIKGACLRVRPVLMTAVTTALGLIPLLLASGTGSEVQKPLATVVVGGLVTSTLLTLLVIPALYKWFVTSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ5</accession>
    <name>A0A1D3RPZ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_11064_0</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000947">
        <property type="protein sequence ID" value="SCN47724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="17600" checksum="F377C39177DB2D89" modified="2016-11-30" version="1">MDCTNRPLKKDFVLNDPDYKDAEILLTRENFGCGSSREHAPWALEDYGFRAIIAPSFADIFYNNCFKNGLLPIVLPAEVVDDLFKEVTAGYQLTIDLDAQTIITPKGQVISFEVDESRKYRLYNGLDDIALSLLQADKIKAYEAERAKRAPWLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ10</accession>
    <name>A0A1D3RQ10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_08831_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001024">
        <property type="protein sequence ID" value="SCN47835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4815" checksum="D2768FE5E13E866B" modified="2016-11-30" version="1">MFGSFYYYSYDFFMLLVRLPYWLKRHIKKSNTTYFALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ38</accession>
    <name>A0A1D3RQ38_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmI</name>
        <name evidence="8" type="ORF">BAZMOX_03410_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000969">
        <property type="protein sequence ID" value="SCN47756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="286" mass="31361" checksum="19CCCD75003C1EFD" modified="2016-11-30" version="1">MPDQYGTLYVVATPIGNLADFSLRAIEILQQVDLICAEDTRHARTLLQHHGITTHCIALHQHNEDHAAQGIIEKIQQGISIAIISDAGTPLISDPGMPLVALAHASNITVAPIPGACALIAALSTSGLPVTQFSFLGFIPRTSSARRNLFNEKKNSTETWVFYESCHRIADCMNDLASVLPPDRIIAIAREITKMHETIIKSSLQDMRTLIETDNNMRRGEFVVMITGAVIDKKEEGLTEQQLKTLKALLQECTIKTAVSLAVEITGARKKLLYQTALELSSNNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ44</accession>
    <name>A0A1D3RQ44_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA large subunit methyltransferase E</fullName>
            <ecNumber evidence="2">2.1.1.166</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">23S rRNA Um2552 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">rRNA (uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rlmE</name>
        <name evidence="2" type="synonym">ftsJ</name>
        <name evidence="2" type="synonym">rrmJ</name>
        <name evidence="5" type="ORF">BAZMOX_210010_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42720"/>
            <dbReference type="Rhea" id="RHEA-COMP:10202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10203"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.166"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.166" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001052">
        <property type="protein sequence ID" value="SCN47875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2 3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FtsJ" evidence="4">
        <location>
            <begin position="18"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2 3">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="196" mass="21884" checksum="9DCD0BB2F1CBAA07" modified="2016-11-30" version="1">MQEHVNDEYVKRAKALGYRSRATFKLVEVLEKDKLILPHMNVVDLGAAPGGWSEYVRKIIGKKQKVIALDILDIEPIEGVDFICGDFRENEVYEQLTDVLDGAPIDVVLSDMAPNISGNKAMDQPSSMYLCELALETAQAILVEGGSFLVKVFQGVGFEEYKKQIDASFDKVLIRKPKASRARSNEVYILGKGFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ66</accession>
    <name>A0A1D3RQ66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lead, cadmium, zinc and mercury transporting ATPase Copper-translocating P-type ATPase</fullName>
            <ecNumber evidence="9">3.6.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_05068_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.3" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000978">
        <property type="protein sequence ID" value="SCN47762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="704"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="727"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="39"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="750" mass="79608" checksum="DEC3718787EB299D" modified="2016-11-30" version="1">MPKQNLLILLDTVLGNIGKKKISLPKSNIIEDLSIPLQDISLAIEGMSCASCALLLEMSLNRDPRIHSASVNFASAIATVQGRLSRQEMAAIIEKVVYKANLMDTLSQRQGLIEKERQRLASAKKRFIWASVLSAPVIAVGMAMPAGRFYHWFQFALTTPVVFVAGATFFSKAWKLAKMGNANMDSLIAIGVGSAYGYSLPSLLRGRGHLYFEAAASIISFVLLGRYMEESAKGKAGEAIRKLVDLQPQTATLLKDGQEMTISIDDIELDDLLLIRPGEKIPTDGEVVAGLSTVDEAMVTGESLPVVKEAGHKVIGGCVNGTGVLTIKATAIGMDTVLAGIIHMVDQAQASKLPVQKLVDKISAIFVPSVMAVSALTFASWTVAGAPFSFAFSSAITVLLIACPCALGLATPTAIMVGTGQSAKRGVYIRNGESLETATHLTAIIFDKTGTITEGKPQVTDFINISDHNTEILLAHIASAEHNSEHFLAKAIVNYAQAEHDFELKTVKDFSVTAGRGLKAKVGHYQILIGNQAWLEEQEVDIAELMPHAHTLGLAGKTPVFTSFNGKATALFGIADQPRDSAKAAIAALHKLNIETLMVTGDTSATAHHIADLVGIKTVIAHATPEQKLQEIHRLQNEGGSVGMIGDGINDAPALAAANVGFAIGHGTDIAIESADLTLVNGDIAKVAETIELSTLTMKIIKQNLFWAFGYNTIAIPVTAIGKLNPMIASAAMALSSVSVIVNSLRINGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ69</accession>
    <name>A0A1D3RQ69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobyrinic acid A,C-diamide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_11216_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="FMJP01001032">
        <property type="protein sequence ID" value="SCN47843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase_3" evidence="3">
        <location>
            <begin position="221"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="314" mass="33605" checksum="BEA86F368199DF78" modified="2016-11-30" version="1">MLALLQYLKAQQHNVVSFKAGPDFLDPLWHQAITGKYSYNLDTRMIGAANSQQLLAKQALTADVAVIEGVMGLFDGRSGVGESGSSAELAKVLQVPIFLVVDAKGMSGSIVPLVSGFCAYAEKMGVKISGIIANRVGSAHHASLLKTVLQEHQQPPLIAWVEKDAPVLPERHLGLMQPSEVALPDFLPFFHVEVADLVALFAEADSHLGEQKPIQLLKGKKIAIAQDAACCFIYPVNLAFLREQGAELVFFSPVAGDAIPNTADAVWLPGGYPELFVQALSISKTWFSLGEFIEAGKPVLAECGGVDVIGRGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ91</accession>
    <name>A0A1D3RQ91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized enzyme of heme biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00676_9</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007470">
        <property type="entry name" value="HemX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38043">
        <property type="entry name" value="PTHR38043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04375">
        <property type="entry name" value="HemX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="391" mass="43279" checksum="5A0A413C3DE0F7CD" modified="2016-11-30" version="1">MGKTVAEVTENIDQKETLSKPKAKESKSGVWFDVVILLIVIGLAGAGYLLLQQVRDKQQDLVGELGKDTQQMFELTKQISGYQEQLVAIQNQLSSLNAEVGSKESNFEAKLNELSALHTERLENTSGRINESILRIQRQLGKTRGDWLVADAEYLLSVANRRLHLMGDVDTTIEALKAADQRLRESGDTAAFKVRGQIAKEIAAVQKVQLADVVGIYSTLEMLEEDVAKLNVFLPYAGKGLSSDDSIAKAKAKSSAENDINAKLDDALVAIEGIVTIRRLDNPVTSVITPEQKAFITEQLSTKLVIVKLALVQQDDALYQASINDVLQWLKSNFTKNAAYKQFVLELERLKAIQIRSNFPDISGSLKMLRDITKLRLETDKALQLPDVQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ98</accession>
    <name>A0A1D3RQ98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_72554_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000998">
        <property type="protein sequence ID" value="SCN47792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4613" checksum="E39D3C9070218D14" modified="2016-11-30" version="1">MAGDRLAELEFRAKPEIVAIDDIDTYFFFLLLPRKQIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB7</accession>
    <name>A0A1D3RQB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">coaBC</name>
        <name evidence="7" type="ORF">BAZMOX_02007_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01001073">
        <property type="protein sequence ID" value="SCN47893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="2"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="183"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="186"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="393" mass="42859" checksum="4A0F296569CE25A9" modified="2016-11-30" version="1">MKRILLGISGGIAAYKSAELVRLLRKNDYEVRVVMTHAATQFITPLTFQALSGHAVHTQLLDASEENAMGHINLARWAELFLIAPASANCMAKLSLGIADDLLSTLYLAAECPVYIAPAMNQAMWNKPVTQENLNRLQRHKVHIIGPGVGSQACGETGYGRMSEPSDIINQLNVLNAPQLLLNKKILISAGPTREALDPVRYITNRSSGKMGYALAQQAQLLGAEVTLVSGPTQLAPLFNIHTLKVESAAEMYSAIMQQVGGQDIFISAAAVADYTPVKLQTEKIKKQGDNTRLSLCKTQDIVASVANLPNKPFTVGFAAETHNLEHYALDKLQRKNLDMIAANWVGKAEGGFDSNHNALQVYWQNGKKTFTMTDKTQLANQLLTLIAERLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC4</accession>
    <name>A0A1D3RQC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Succinyl-CoA ligase [ADP-forming] beta chain</fullName>
            <ecNumber evidence="8">6.2.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_30116_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.2.1.5" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01001076">
        <property type="protein sequence ID" value="SCN47900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="9"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="354" mass="38380" checksum="68D86A4169D8DE16" modified="2016-11-30" version="1">MNIHEFQAKQLFRDYKIPVPESSVVTSAEQAFTAVHALPSDSWAVKAQVHAGGRGKVGGVKIANTTAAVVDSVNQMLGQQLITQQTTAAGLPINSILIEQTTAIKREFYLSLIIDRHAEKLCFIASIAGGMDIEAVAAATPEKIISLFIHPAAGLQAYQCRQIAFAFDLQGEQLKALHQLMAGMMQLFLDKDASQIEINPLVETETGELLALDAKINFDDNACALHKDILALRDTRQEDEKENTAKQFDLNYITLEGNIGCMVNGAGLAMATMDLVKLKGGTPANFLDVGGGTTIEKVTEAFKLIVSDKNVKAVLVNIFGGIVRCDVIAQGSFRCISANKNRLTRDCSFRRHSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE5</accession>
    <name>A0A1D3RQE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_249321_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001092">
        <property type="protein sequence ID" value="SCN47923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4922" checksum="F6CB8F6645BB6816" modified="2016-11-30" version="1">MTHVIQVLFLSVFILQVVMHGEESQVPGELRQSEILIEQDSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQI4</accession>
    <name>A0A1D3RQI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
            <ecNumber evidence="1">3.5.4.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03957_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.5.4.10" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01001071">
        <property type="protein sequence ID" value="SCN47892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="306" mass="32741" checksum="C530D8CD30C7A16F" modified="2016-11-30" version="1">MRYGENPHQNAAFYQEKSPASGTISAAKQLQGKELSYNNIADTDAALECVKSFEEKPTCVIVKHANPCGVAQADSLLDAYDLAYATDPTSAFGGIIAFNRELDEATAAEIIKRQFVEVIIAPTVSAAAQTLLAEKKNVRVLESGIWNSGNEPCFDFKRVSGGLLVQDKDFGTMSVAEVIVVSKRAPTEQEMADLLFTWKVAKFVKSNAIVYCKEGRTIGVGAGQMSRVYSAKVAGIKAADEGLSVTGSVMASDAFFPFRDGLDAAAEAGITAVIQPGGSMRDAEVIAAADEHNIAMVFTGMRHFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-11-11" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0K2YV25</accession>
    <name>A0A0K2YV25_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1863 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_114159_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000814">
        <property type="protein sequence ID" value="SCN47543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036490">
        <property type="entry name" value="MTH538_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015032">
        <property type="entry name" value="MTH538_TIR-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08937">
        <property type="entry name" value="DUF1863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52206">
        <property type="entry name" value="SSF52206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1863" evidence="1">
        <location>
            <begin position="5"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="137" mass="15695" checksum="35B0FF13DF6B9BE8" modified="2015-11-11" version="1">MADPRAFISFDFDHNETEKKLFVGQSKNHKTPFTIQDWSAKSSMPQSQWETIVKEKINKTNMLIVLVGKYMTSAIGVAKEISMAEDQNVPVFGIYVDGANTNSNLPKGLQRNRTIVWDWDKTYNEINRMMCEGKNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL45</accession>
    <name>A0A1D3RL45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_18013_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000002">
        <property type="protein sequence ID" value="SCN46390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021979">
        <property type="entry name" value="DUF3584"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12128">
        <property type="entry name" value="DUF3584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="77"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="262" mass="30510" checksum="52CDA4B7ABE20789" modified="2016-11-30" version="1">MQSMRERQVDTATLTALELKVNALKQELAAAENAELLVGQYQRWLDVEWQNYDAIQSDLITCAASEQQQNQQYAAVYTTYQQQRKTLDDRLEQIKNSIKKYEKEVGTLKKVLEDLALYPKKIPEQVSFDSSHHLNLLQGHFKILSAKHKTQRKELTDLVRHLKRVLSKIPNTRPSSYYLAFDNELGVDSDEMQWLPAIQDWFISSADDTRRWLVMQAQTFGSAIRNYQQALQRFDRGIDSLSRRLAANIDQNISFEKIESIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL51</accession>
    <name>A0A1D3RL51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04471_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000015">
        <property type="protein sequence ID" value="SCN46403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="77" mass="9046" checksum="B2F49944C835BA38" modified="2016-11-30" version="1">MIAIFYPWEGKIQPEKYPLKKNEDYYNDLFCTSLGGQREVKHDYKYGAKKSYVKVDCETVDYVYEGGMDKRSSLDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL61</accession>
    <name>A0A1D3RL61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_267854_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000018">
        <property type="protein sequence ID" value="SCN46413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4513" checksum="514806D1359BCF19" modified="2016-11-30" version="1">MNGYQTVPELQSGLKRYFEFYNQERLNYQTPSNVHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL86</accession>
    <name>A0A1D3RL86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00432_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000065">
        <property type="protein sequence ID" value="SCN46475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="254" mass="29489" checksum="04C40D165E12A67D" modified="2016-11-30" version="1">MIFIAPNQKGGVGKSTFQNQIMSAYLYSKSNKKVRLIEIDDENEDSIVFTKTEILDAKIMHTSEIRKLDEIFYEKDDIVIDVGGNKTSTILLEEVKKIGEYENIIWFIPMGSGEMDSTNALSVYEEIMEMNEKAKVIFILSNAKTDDEEWEFMNFFGSDFLDIEFAILDHIPTAKHITIKNSTVINHARFSHKTFLDLALDETDYRAEYKALKKDKKDEDASKKLKLRRLKNEAIKYLEYLKIDVFPKLDELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL92</accession>
    <name>A0A1D3RL92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_267854_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000018">
        <property type="protein sequence ID" value="SCN46414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="57" mass="6393" checksum="E92FB53D17A6387A" modified="2016-11-30" version="1">MRGKWTYLYRAVDSQGDTLDFMLSECRDEDAASAFLKQAINNNAFPDKIVMDTSGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL96</accession>
    <name>A0A1D3RL96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Quinone oxidoreductase</fullName>
            <ecNumber evidence="1">1.6.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04566_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.6.5.5" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000071">
        <property type="protein sequence ID" value="SCN46485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:NADPH:quinone reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="111" mass="12506" checksum="C6103D6944DA1B8E" modified="2016-11-30" version="1">MIGGDYFPRNIKCLNFDGRLVHIALQNGIKAEINLLPIMLKRLSITGSTLRARNTHFKAKIAQQLQENVWPLLASGQIKPIIHQTFPLAEAEKAHVLMESSEHIEKIILTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLA4</accession>
    <name>A0A1D3RLA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_293061_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000026">
        <property type="protein sequence ID" value="SCN46424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038472">
        <property type="entry name" value="DndE_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="81" mass="9056" checksum="CC5C0A704C9A0BDB" modified="2016-11-30" version="1">MLTIREGGPLSNAGVGNMEGGQELNDTTLFGEHIYLYDILINQYIYDKQLNLTVGETIVALVEIGIFKMGHIRELEQLCDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-06-17" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLA8</accession>
    <name>A0A1D3RLA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_11757_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000058">
        <property type="protein sequence ID" value="SCN46461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="128"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="217" mass="24208" checksum="24E411E870E4879A" modified="2016-11-30" version="1">MNDTLGHHIGDLLLEKVGIRLTACLRGVDTIARLGGDEFTVILNTVQTKEHAAIVAEKIITSLARPFKIHSHLIHIGSSIGITAYPEDGDDLDAMFKHADMAMYDVKEKGRNAYAFFSSNLTTYVNHRMELEKDLRIALDNNELYLNYQPIISLHDNNICGVEALLRWRHPTLGQISPEKIISISEESDLILALGEWILRTACAQPVRSLAHGKNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLB4</accession>
    <name>A0A1D3RLB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00432_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000065">
        <property type="protein sequence ID" value="SCN46471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="172" mass="19883" checksum="FCF426B38E0C5D71" modified="2016-11-30" version="1">MIVSDTLEHGSIKNIAIGELYTMLEIMKHEIQKGVKFIAIDSTLEFYVHDLRGEEEVTTIFRELALIAKKHDVLVITISQGSKEDNKEDIISIFGSQKAKHFATSMFHIFYDTETEKRTFAVAKNKQEGGRFKQEIYLNTDTFTFNEFEVVVEEDKKVVVEEDKKPSVWDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLG1</accession>
    <name>A0A1D3RLG1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_84129_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = diphosphate + GDP-alpha-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the mannose-6-phosphate isomerase type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000083">
        <property type="protein sequence ID" value="SCN46502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006375">
        <property type="entry name" value="Man1P_GuaTrfase/Man6P_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01479">
        <property type="entry name" value="GMP_PMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="3"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="MannoseP_isomer" evidence="7">
        <location>
            <begin position="311"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="466" mass="51516" checksum="89B992C1181551E0" modified="2016-11-30" version="1">MIPVILSGGSGTRLWPLSRGIYPKQFLPLVSDKTMVQETVLRLKGIEGLQAPIAICNEDHRFMMAEQLCRIDIHPECIILEPIGKNTAPAVTMAALAAKDPEDILLVLPADHVIGNVAAFQAAVIKAGELAQQGFLVTFGIVPTAAETGYGYIKRSYENIAEAFKVAEFVEKPNTEIAQAYVDSGEYYWNSGMFAFKAGCYLQELEKFAPEMLSACRSSFAAAKVDADFVRLDKELFAQCPADSIDYAVMEKTDKAVVIPLDAHWNDVGSWSALWDVRAKDSRGNALSGDVLALDTENSFIHSENKLVAVIGVKDLVIVETDDAVMIAPKDRVQEVKVIVNTLKQQQRCEADLHRKVYRPWGHYDSVDHGERHKTKRIVVKPGAKLSVQKHHHRAEHWVVVKGTALVTKGGETMLLSENESTYIPLGVIHSLENPGVIPLEMVEVQSGSYLGEDDIVRFEDKYGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLH9</accession>
    <name>A0A1D3RLH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxygen-dependent coproporphyrinogen-III oxidase</fullName>
            <shortName evidence="4">CPO</shortName>
            <shortName evidence="4">Coprogen oxidase</shortName>
            <shortName evidence="4">Coproporphyrinogenase</shortName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hemF</name>
        <name evidence="5" type="ORF">BAZMOX_17371_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:18257"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="1.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000135">
        <property type="protein sequence ID" value="SCN46565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00333">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018375">
        <property type="entry name" value="Coprogen_oxidase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="PTHR10755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="SSF102886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01021">
        <property type="entry name" value="COPROGEN_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="113"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for dimerization" evidence="4">
        <location>
            <begin position="245"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="263"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for dimerization" evidence="4">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="307" mass="35261" checksum="9C2B3C3A88A71072" modified="2016-11-30" version="1">MAEISNIEIERVKAFLLGLQDSICTGLQDEDGGAVFVEDSWDRVEGGGGRSRILTNGHVFEQAGVNFSHVFGHKLPPSATAKRPELEGRDFQAMGVSLVIHANNPYVPTSHANVRFFIAEKEGEEPIWWFGGGFDLTPFYPFKEDVISWHQVSKAACEPFGDDVYAKYKKWCDEYFYLKHRDETRGVGGLFFDDLNEWGFEKSFAFMQSVGEHYLPAYLPVVSKRKAMEFGERERDFQLYRRGRYVEFNLVFDRGTLFGLQTGGRTESILMSMPPVVHWKYNWHPEAGSPEAVLYDHYLQAHDWLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLJ8</accession>
    <name>A0A1D3RLJ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GtrA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_20286_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000115">
        <property type="protein sequence ID" value="SCN46540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="703"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="730"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="764"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="10"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="796" mass="90686" checksum="0E7DAE91F3BE697F" modified="2016-11-30" version="1">MIELNWKTVRFIVIGVLGALVYFFCSYLLLSYTELPAFLASLFAYACSFGFSYLGQKVWAFRSIAPHSVTLFRYAVLQACCATFAAIFTQVSVLYSDWSALLLSGLAAVLTSGISYIVSSRWVFTNSSEQSFQSAHVENIVYRGAEYQYWPSGLWALLWVSLSTIYVTLYYYMPLAINLAAEHDDNLFVTQAYSLAAGDWLGKYSQFTLMKGPGYSLFLALTHFMGLPLYFITAIFHIIAVSSFAGVLYRLSQSRLFSILVFVLLLLLPLVISNGRIIRDQIYPDQFLLGFAALIFSFFIADSWLKRSSSALLAGLMFAWFWLTREEGVWIVPSVVLLTLFAIWRFWRINSLKQGLISSVLVLILAFSSVHIIFQLINWHIYERFAGLDIKEKNFQSTLSALQSVRVGEPISHVPVSQETRQHIYRVSPAFAELKHYFSHSGWENAGCPIYPWACKEIAGGWFIWALRDAAATQGYYQSPAQAAAFFARVATEINRACTDGRLICEKSLVSYMPRVVQQDIDQASSILEQLLDVLLLSHYTVTNSTIKRTLLKDEQSLLRFLHSEYRFVRDSKVEVFGRYADDQNNKGQLNLTISNQQGIFFPYRLSQASISEKNKFYPFRLETSCPEGCTLTINIDGKEKLKLAIPDFDQVFTAKQVITLGGVKVFFEKVMHAERQYKAVTELGERTTYKLRQVLLVSYQSIFPVLLYLGLISFAMLTIVAIKQRNFSVLFVINAAMWGAMLVRLTILFLIHISSFPTFNPLYFMPVYSLLIIAPMISLYLWGKVLYKYFGSFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK5</accession>
    <name>A0A1D3RLK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_61653_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000104">
        <property type="protein sequence ID" value="SCN46524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="212" mass="23367" checksum="39FA27474EE1E82E" modified="2016-11-30" version="1">MQDGKIVPPGAFLPAAERYNSAPRIDRWVVHHTLQWLSCHADQLHHVGSIAINLSGQSLGDEAVLTYIMQQFESSDVPAEKIKFEITETAAIANLQDATVFINTLSKFGCQFALDDFGSGLSSFAYLKNLSVDVLKIDGMFVKDMLDDPIDSEMVKSINQIGHVMGLETIAEFVENEQILDKLRDIGVDYAQGYHLGKPIPIASLLNSNNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK9</accession>
    <name>A0A1D3RLK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="9">1.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_07213_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000124">
        <property type="protein sequence ID" value="SCN46550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="193"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="248" mass="26426" checksum="113AC9A57E51B44A" modified="2016-11-30" version="1">MGFMQGKRVLIVGLASNRSIAWGIAQAMHREGADIAFTFQNEKLQSRVEKMAAECNSNITIECDVSSDEQIDNVFIELGKHWDGLDCIVHSVAFAPRDALDGDFVNATTRENFRIAHDISSYSFTALAKAGREMMAGRNGSLLTLSYLGAERAIPNYNVMGVAKASLEANVRYMAVALGAEGTRVNAVSAGPIKTLASAGINNFKSMLSKAADTAPLKKNVTIGEVGNVSAFLCSDLASGITGESHLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL4</accession>
    <name>A0A1D3RLL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_16396_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000110">
        <property type="protein sequence ID" value="SCN46534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025455">
        <property type="entry name" value="DUF4276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14103">
        <property type="entry name" value="DUF4276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4894" checksum="69181D7FFE8C350F" modified="2016-11-30" version="1">MIGYKKVVMGKVISESIGIMRIRQQCLHFDDWLQRLEKLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL9</accession>
    <name>A0A1D3RLL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04471_6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000015">
        <property type="protein sequence ID" value="SCN46408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014057">
        <property type="entry name" value="HI1420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40275">
        <property type="entry name" value="PTHR40275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02684">
        <property type="entry name" value="dnstrm_HI1420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="93" mass="10435" checksum="A75876C3D4823D5F" modified="2016-11-30" version="1">MAIELKPYNPVEFFHNEEEIISYLNEAYSDDDPSVFLVALGHIAKTQGMANLAKITGLNRESLYKALSGETQPRWDTVQRIVKGLKINLKAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM7</accession>
    <name>A0A1D3RLM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_313795_0</name>
        <name evidence="1" type="ORF">BAZMOX_437783_0</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000153">
        <property type="protein sequence ID" value="SCN46581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000996">
        <property type="protein sequence ID" value="SCN47788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4624" checksum="9F2F6AB5B38803CF" modified="2016-11-30" version="1">MYEAIKKLEMENDYEGIKNLYSNEEIKVHQFGYILEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN3</accession>
    <name>A0A1D3RLN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_376024_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000143">
        <property type="protein sequence ID" value="SCN46572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4579" checksum="910CD4EC9EED660B" modified="2016-11-30" version="1">MPPSRTAIAVHFGLANFPVAYCGLKIITSLSLRFPDFQREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN7</accession>
    <name>A0A1D3RLN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_57212_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000028">
        <property type="protein sequence ID" value="SCN46428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4418" checksum="3483210017B63C8E" modified="2016-11-30" version="1">MYVDIQDYQYAALFKNNGANMINIKNNFIPNINLGRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP5</accession>
    <name>A0A1D3RLP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_86138_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000156">
        <property type="protein sequence ID" value="SCN46586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4269" checksum="A90BF104831706F6" modified="2016-11-30" version="1">MVINSTNMNKGIELLFIFRVTYALKGIVDIYLFSSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR2</accession>
    <name>A0A1D3RLR2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">KORA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00589_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000166">
        <property type="protein sequence ID" value="SCN46602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032428">
        <property type="entry name" value="TrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16509">
        <property type="entry name" value="KORA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KORA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="76" mass="8827" checksum="86931135845D8E26" modified="2016-11-30" version="1">MSYEILVNQKSSEEVGRKFGVTRQAAHKAALRVWRSHLESIDCPEGWTSIELIVPPELKERFEKIQQQLLIKHSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR4</accession>
    <name>A0A1D3RLR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type IV secretory pathway, VirD2 components (Relaxase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00589_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000166">
        <property type="protein sequence ID" value="SCN46606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021795">
        <property type="entry name" value="DUF3363"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11843">
        <property type="entry name" value="DUF3363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="605" mass="69548" checksum="B3C95308A750EC35" modified="2016-11-30" version="1">MAESVYNVGSSARRVVVKARVVKMNNSYGKKSAGLHMKYIERDGAGKDGKEAELFDSKTSNKDLTEWTEKNIEWAEHTEGEPHQFRVIISPEDAHELNLTEYTRELMERVQTDLGRDLVWTAANHYNTDNPHTHLVISGLDKNGEEVWIDREYISNGIRNRARELATQELGHRSEHEIDTTLNKEITQERFTSLDWKIDKVSHGNIVDMSVYPDDIDARKLHGKLIARLDHLVGYGLAIKDNSHEYILQDGWDTNLREMGERDDIIKTLHKEIKADPTKYRIYDKDDHDNVVTGRLVRSGLHDELNDRFYMIVEGQDGSANYIVMDKGTDVTEYKRGSIVSVENYQDSWIKKSDYVIETFARSNQGIYDQKEHVKQVIKHPELLPNGVTPEGYTDAISRRVSRLSRFGLAQQLGSGLWKIEDNLTAELSRRDQESPNPRKVRISTIDERLLQQQIKAEGRAWIDTIHVENNAPYSFGSELNQAIKKRQEFMQKELGLKGNEKGLLKMLDNIERQKLVQDYADSSLRRYKPLKQEMFTGTLQKKITAPSGQGYVLITSEHNNSIDKEFSLVPWRDNMKRSLGKPVSFGLSKQNIPIVKTLTKGLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS7</accession>
    <name>A0A1D3RLS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_105338_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000108">
        <property type="protein sequence ID" value="SCN46529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="38"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="17094" checksum="E41C8A6C6A301569" modified="2016-11-30" version="1">MAFYFVSTFATAQTPTKQRPYGYRGLPALAFALHGWQRAAATAFFKQAINNNGFPDKVVMDKSGANYEGLANINLLLILAGFATMIDICQVKYLNNIIRTGPSIYQKVTKPMMGFKAFHSAQATIAGIETAHMIRKGQLSKENMPAYKQFMTLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU3</accession>
    <name>A0A1D3RLU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="8">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glycyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="8">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glyQ</name>
        <name evidence="9" type="ORF">BAZMOX_35272_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000185">
        <property type="protein sequence ID" value="SCN46636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00733">
        <property type="entry name" value="GlyRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="306" mass="34897" checksum="34886AF0E66602DE" modified="2016-11-30" version="1">MSNSNNDLSTFQGLILALQNYWSEQGCVLLQPLDLEVGAGTFHPATFLRAIGPEPWNAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVLKPSPDDIQALYLGSLRHIGLDLLEHDVRFVEDNWESPTLGAWGLGWEIWLNGMEVSQFTYFQQVGGLECRPVTGELTYGLERIAMYIQGVESVYDLVWSKGPQGIVTYGDVFHQNEVEMSAFNFEHAKVDFLFESFDIYETESAKLIEQDLPLPAYEMVLKASHVFNLLDARHAISVTERQRYILRVRNMSKAVAETYYARRESLGFPLVKETGVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ0</accession>
    <name>A0A1D3RLZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glutamate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_317629_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000218">
        <property type="protein sequence ID" value="SCN46691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006536">
        <property type="term" value="P:glutamate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="PTHR43321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="111" mass="12693" checksum="D5CBF85A119F7A64" modified="2016-11-30" version="1">MLAIWTKATRLRYFEVLTDSNFLPTVVVKLKGAPKFSAFHISDELRKNGWIVPAYTLPAEANEIVVLRMVIKENFSRDLAEKLFSDTLRAVEYFENLEGITQTKTKTHGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM03</accession>
    <name>A0A1D3RM03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_210005_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000222">
        <property type="protein sequence ID" value="SCN46696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4267" checksum="916B2F98DCD4E048" modified="2016-11-30" version="1">MQQSSLRDSGLVLIVNCTFNGIGTKLEPLARRFNSNKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM24</accession>
    <name>A0A1D3RM24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_145843_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000240">
        <property type="protein sequence ID" value="SCN46722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="70"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="16373" checksum="79492890ED542833" modified="2016-11-30" version="1">MISFKGTHFPKDVILYAVFFYVRYGISYRDLEETMEERGVNVDHATLNRWVIRYAPAIATKAHSQKRNTNRSWRMDETYIKVKGKRVYLYRAVDSHGDTLDFMLSERRDEDAAAAFFRQAINNNGLPDKVVMDKSGANLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM27</accession>
    <name>A0A1D3RM27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Type I restriction-modification system, specificity subunit S</fullName>
            <ecNumber evidence="6">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_354429_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000233">
        <property type="protein sequence ID" value="SCN46713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="5">
        <location>
            <begin position="2"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="153" mass="17266" checksum="803DC9DA230D8EE4" modified="2016-11-30" version="1">MEWKVLGDEQFFEVANKDRKPVKSSLRVSGEMPYHGANNIQDHVEGYTHNGEFVLIAEDGSASLENYSIQYATGKFWANNHVHVVRGNDRVNTRFLHHYLTTVNFIPFLSGGGRAKLTKGKMIEITIPIPCPNNPEKLAGNSSRNCPHTRHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM45</accession>
    <name>A0A1D3RM45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00686_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000262">
        <property type="protein sequence ID" value="SCN46752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="5029" checksum="81D2130C9753E9AD" modified="2016-11-30" version="1">MTTLKVFQLLEILMHFNLTQSEILIRYEPYMKLSTRKTQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM57</accession>
    <name>A0A1D3RM57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_11336_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000123">
        <property type="protein sequence ID" value="SCN46547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5485" checksum="96AD0B3D7EB3F5DD" modified="2016-11-30" version="1">MTHVGKPQTIKQQCKHLHVEKLLHMYKAIENFMSSHVQFAIKKTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM61</accession>
    <name>A0A1D3RM61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate-dihydroxyacetone phosphotransferase, dihydroxyacetone binding subunit DhaK</fullName>
            <ecNumber evidence="2">2.7.1.121</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03539_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.1.121" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000250">
        <property type="protein sequence ID" value="SCN46736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047324">
        <property type="term" value="F:phosphoenolpyruvate-glycerone phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012736">
        <property type="entry name" value="DhaK_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02363">
        <property type="entry name" value="dhaK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="1">
        <location>
            <begin position="7"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="328" mass="35039" checksum="9EE20194C587E562" modified="2016-11-30" version="1">MKKFINEIDTLYTESLEGFAKAHADIIQLNTEPYFISRASSTHKNKVAIISGGGSGHEPLHSGFVGKGMLDAACPGQIFTSPTPDQMLAAAEVATEAGVLFIVKNYAGDVMNFEIAAEMLECPNASVLVDDDVSLPKTHSTGRRGVAGTLIVEKIVGAAAENGADLTACKVLAERVNNNTASMGVALTSCTVPALGEPTFEIDAQEMEMGVGIHGERGHKTMPLATATEIVKTIAEAIEADLKPQKGQSALLHINGLGATPLMEQYLIYDLAEKFWQKRGINITRSLVGNYTTSLDMAGVSITLTLLDDEMTQLWDAPVHTPHLRWGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM94</accession>
    <name>A0A1D3RM94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_25285_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000269">
        <property type="protein sequence ID" value="SCN46766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="50" mass="5786" checksum="2C0F99F86E043979" modified="2016-11-30" version="1">MAPQKIKDPILFNFHYTPLALQLPNFIPMTYATVIKEVSIDTPSIFYLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC0</accession>
    <name>A0A1D3RMC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_26729_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000310">
        <property type="protein sequence ID" value="SCN46820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="80" mass="9221" checksum="C325B18E7B35EEAF" modified="2016-11-30" version="1">MKKPKMENLDGLTPDDDFTKTVQAESDKAQKVLKKTFSLQQRDFDYINAQAVIMSQEERKPVSASSALRYIIQRDRSARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD5</accession>
    <name>A0A1D3RMD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_26729_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000310">
        <property type="protein sequence ID" value="SCN46823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="191" mass="21959" checksum="59D3B69A3DC6C100" modified="2016-11-30" version="1">MSKCNLTVFEGDEEIYSNPIINNYIKVDRQKYLDNTKALHVAQLSVFISHAVNTLQYRQFNLKRLTACKEQLSGWILKRLIARFTYASLTTTHDLYYSSIKAASLLLRAKKESDNRTKVLTALNELKANGTIYSYEIEEKREGRKIVDIKYRITPSSEFSSEQKAANKRANIIEQKAVKNDLQSVDKSKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME2</accession>
    <name>A0A1D3RME2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_05000_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000317">
        <property type="protein sequence ID" value="SCN46840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042268">
        <property type="entry name" value="BamC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010653">
        <property type="entry name" value="NlpB/DapX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06804">
        <property type="entry name" value="Lipoprotein_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="200" mass="22592" checksum="937CCFC1A0098C24" modified="2016-11-30" version="1">MSFNLSLTSGMKLSKISLIFSVTLVTACSSFFPDKEKDYIYSKEIAALEMPPNLSEEQSADPLPIDTTPSALTNTVEFIQDNEGSYLLINSSFAHVWRVTGKALTERSIEITDKIRSIATYYVQYDQNVQDVKDGSFWDELVFFLAMTRIKKTVSSFLQQSEQGIRIFVRDEEGNNLSEGNGLHLLNLLFDTIKKDFATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF8</accession>
    <name>A0A1D3RMF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonucleotide reductase of class II (Coenzyme B12-dependent)</fullName>
            <ecNumber evidence="3">1.17.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_02006_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.17.4.1" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000332">
        <property type="protein sequence ID" value="SCN46862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006142">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004042">
        <property type="entry name" value="Intein_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14528">
        <property type="entry name" value="LAGLIDADG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00379">
        <property type="entry name" value="INTEIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="SSF55608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01443">
        <property type="entry name" value="intein_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50819">
        <property type="entry name" value="INTEIN_ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOD-type homing endonuclease" evidence="2">
        <location>
            <begin position="9"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="INTEIN_C_TER" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="662" mass="73431" checksum="65AB56F4FC6047EB" modified="2016-11-30" version="1">MYSENQGYLIGLLIGDGTLKEDKAVLSVWKSTQAVNANSGTVNAGINAIMDKALNASREFTTRSDFTGWSEIAGRNEHRLSFAGLKHFAEELGMSAGNKSITPSIESASSDFYKGFLQGFFDADGSIQGTQEKGVSVRLAQSDLARLEAVQRMLLRLGIKPSIYRNRRPAGIKQLPNGKGGHADYQIKAQHELVISGENLVNFQELINFTDTNKALKLKSALSSYKRSLNRERFTAIVEAITPDGIEDVFDIQVPGINTFDANGLHAHNCGEQPLPPYGSCLLGSINLTRFIQDPFTENAAFNWDAYRKTIRIFTRMLDNVVEINGLPLEKQREEITSKRRHGMGYLGLGSTLTMLGMQYGDDASLGFTSEVTKVLAVEGWKEALELAKEKGTAPALEKMYGVTGRMLHKRPEMVTDGYKIGDKVAGKVLHAKYSRYMQKIAEAEPELIAALIEQGARFTHHSSIAPTGTISLSLANNASNGIEPSFAHHYARNVIREGKKSKEKVDVFSFELLAYRELINKKAMPYSEAKDEQLPGYFITADAITPKQHVDVQAAAQVWIDSSISKTANVPTDYPYEDFKSIYQYAYDKGLKGCTTFRFNPEVFQGVLVKESDLENTTYQFTLEDGHVLEVKGNQQIEYDGEMHSAANLFDALKEGYYGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMG3</accession>
    <name>A0A1D3RMG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell division protein FtsH</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02753_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000257">
        <property type="protein sequence ID" value="SCN46749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="119"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="327" mass="36297" checksum="52CDFA80BEAF681C" modified="2016-11-30" version="1">MAMANQLKALLKSYVDGDNGMFLSVAMQVAAHEAKQGHGKLAKEIRELIDQAKSQHSGDNLTPIPLVKPKGELNNLLSVSYPKLRLVDMVLSTSIGAKLQRLIKEHKHVLQLRTHGLSPRKKLLLVGPPGTGKTLTASVLAGELGLPLFIVRLDSLMTKYMGETAGKLRLIFDAIQQTRGVYLFDEFDSIGSQRGNINDVGEIRRVLNSFLQMIEEDASDSLLIAATNHSELLDHALFRRFDDLIEYDLPEKKEIIAALKSKLASFKTSRIQWTEAAAAAEKLSYGDITRVCEDAIKDVIIHNRESVTHTNLIHSIKERCAVSQKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML8</accession>
    <name>A0A1D3RML8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_11241_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000348">
        <property type="protein sequence ID" value="SCN46886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="61" mass="6975" checksum="4FC2C699D2E4D8D3" modified="2016-11-30" version="1">MSDLARERIKFITELHEVFLVNKGFGAFAYVSINDVLALFEEYLASGEPAKQIINRYVHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP4</accession>
    <name>A0A1D3RMP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00523_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920246" evidence="1">
        <location>
            <begin position="22"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="149" mass="16731" checksum="F07FC9E1019FAF1A" modified="2016-11-30" version="1">MKNLKVTIALLATMAITPSYAEIIEIDEYTELETDTVLVNAGLVVIKDKEGGILCINNINSEIDLHDGEVYIIRGQWTETLYRGVMTDADTNPVLELTQQFETHDDMDGDKIYTGEITYVGIYGDETELNYIWARGTMGSTCKINVNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR7</accession>
    <name>A0A1D3RMR7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type I restriction enzyme endonuclease subunit</fullName>
            <shortName evidence="2">R protein</shortName>
            <ecNumber evidence="2">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_18360_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Subunit R is required for both nuclease and ATPase activities, but not for modification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">The type I restriction/modification system is composed of three polypeptides R, M and S.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000409">
        <property type="protein sequence ID" value="SCN46963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004473">
        <property type="entry name" value="Restrct_endonuc_typeI_HsdR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00348">
        <property type="entry name" value="hsdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="693" mass="78838" checksum="426FF3021E59C51F" modified="2016-11-30" version="1">MIEGQIKKGLIWHFQGSGKSLLMVFAAQKLRKATELKSPTVIVLVDRTDLDTQISGTFNAADVPNVESTDSIKELQTMLERDTRKIIISMIHKFRDAKPNMNLRDNIIVLVDEAHRTQEGDLGRQMRAALPNAFLFGLTGTPVNKADKNTFWAFGAEEDQGGYLSRYTFHDSIRDEATLPLHFEPRLVDVHVDKEAIDQAFAVFKESTALSDEEADALNQKSAKMAAFLKSPERIEKIVTDIATHFKEKVAPQGFKAMIVTPDRYACVLYKEELDKHFPTEASRVVISTTANDDYEFKQKWAMDKSAQEKTVDEFNDAQSELKFIIVTAKLLTGFDAPILQTLYLDKSIKDHTLLQAICRTNRLYPQKSFGRIVDYFGVFDDAAKALEFDEESVKQVITNLSALKEKLPEAMRDALAHFPNVDRTLEGFEGLEAAQNAINNNDKKDAFARDFKYLAKLWESLSPDNILDLYNQDYKWLAQVYESVKPASGNIGKLLWLTLGAQTTQLIHDNVHVGEVHQLEEFVLDADVIEDIFNNPDPKKNQGTGKDLIKRFQKHAGDPKFKKLSERLEELRDKAEKGLISSIEFIKELCKLAKETILAEKELEQSMQDKTPKAALTELFLELKTDQTPAVVERIVTDIDAIVRIVRFPGWQQSVSGEREVQKSLRKALLKYKLHKDQALFERAYGYIKEYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS6</accession>
    <name>A0A1D3RMS6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_86853_3</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000300">
        <property type="protein sequence ID" value="SCN46808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38039">
        <property type="entry name" value="PTHR38039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="84" mass="10395" checksum="FA734207442F4E28" modified="2016-11-30" version="1">MILSWADHAWNDYLYWQKTDKKILKRINLLIENIKRHPFEGSGNPEPLKHNWSGYWSRRINREHRLVYKVLDESIIIVQCRYHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT3</accession>
    <name>A0A1D3RMT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactoylglutathione lyase</fullName>
            <ecNumber evidence="2">4.4.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00824_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.4.1.5" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000397">
        <property type="protein sequence ID" value="SCN46956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="146" mass="16816" checksum="3D54E1A8B5D8AC49" modified="2016-11-30" version="1">MRYLHTMVRVKDLTASLHFYCAQLGLQETQRIENEAGRYTLVYLNAPEDAEQAKSNHSPLLELTYNWDTEDYTGGRNFGHLAFEVDNIYSFCQDLLDKGIIINRPPRDGYMAFIRSPDEISIELLQKGNRLPPAEPWVSMQSTGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT9</accession>
    <name>A0A1D3RMT9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="5">3.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_06086_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="5">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000338">
        <property type="protein sequence ID" value="SCN46869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="7">
        <location>
            <begin position="137"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="376" mass="41341" checksum="E52AE92632D2DCF4" modified="2016-11-30" version="1">MTIQTAVLIETLTALGAEVRWSSCNIFSTQDQAAAAMAAAGIPVFAWKGETEEEAEWCIEQTIIGPNGWRPNMILDDGGDLTVMMHEKFPELMADVKGLSEETTTGVLRLYEMVTEGTLKVPAFNVNDSVTKSKFDNLYGCRESLVDGIKRATDVMVAGKIAVVCGYGDVGKGCAQSLRGLGATVWITEIDPICALQASMEGYRVVTMEEAAPLANIFVTATGNYHIINHKHMLAMKNNAIVCNIGHFDSEIEIAALRQYTWDNIKPQVDHVTFPDGKKLIILAEGRLVNLGCGTGHPSFVMSNSFCNQVLAQMELWENAADYENKVYILPKKLDEKVARSHLAQLGVQLTQLTPEQAKYISVPVEGPYKADHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMU2</accession>
    <name>A0A1D3RMU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell division protein FtsI [Peptidoglycan synthetase]</fullName>
            <ecNumber evidence="9">2.4.1.129</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_00289_3</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.4.1.129" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000434">
        <property type="protein sequence ID" value="SCN47000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02080">
        <property type="entry name" value="FtsI_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037532">
        <property type="entry name" value="FtsI_transpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0717">Septation</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="8">
        <location>
            <begin position="63"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="7">
        <location>
            <begin position="270"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="585" mass="64270" checksum="E2CCFE1FCD19DABE" modified="2016-11-30" version="1">MLALKKKKNISKIVEFSGRRKLVLVFMFLGVCVLILKAIQLQVMETQFLQKEGRSRQVSTVKTAAYRGQIQDRNGKSLAVSAPVASIWVNPQYCREAEAESEDPKSICSNLTDIRFKQAAKLLGMSLRKLLKAFDASTNKQFVYLKRHIEPSVAAEIKALGLPGVGFIREFKRFYPAGEVAAHLVGFTNIDDKGQEGLELMYNSSLKGVAGSKRVIRDGKRRIIEGQNLEGIKEPVNGQDLQLSIDERLQYLAYKELKAGVVRHRAKSASLVMLEAETGNVLAVVNQPSFNPNVRKNLKVSRYRNRAITDIFEPGSTMKPLVVAAALEGGFIKPNQLFDTRDFKIKGRWVRDGHKHGTMDLTAVLKKSSNVAASKIALSMPPSYFWRFYHDLGFGVSPRVNFPGEASGALPEYSGWSDFEQATLSFGYRVSMSTLQLARAYTALADDGVLHSVSLLKREKDEYATQVLSPETAIKVRTMIEQVVQKGGTATKAKVDGYRVAGKTGTVKKVSRQGGYGNDYLSVFVGMAPASDPKLVIAVMVDSPQGAYYGGLVAAPIFAKVMGGALRVLGIAPDEEQTMSVLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV6</accession>
    <name>A0A1D3RMV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavoprotein wrbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_38472_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000448">
        <property type="protein sequence ID" value="SCN47021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="198" mass="21144" checksum="61724FBA5FA30B7D" modified="2016-11-30" version="1">MVNILVLYYSRDGATKAMAQQIARGIESIKNAEAILRTVPNISSICEKTADEILASGSLYVSLDDLKHCDGLALGSPTHFGNMAAPLKYFIDNTTEAWFSGSLSDKPAAVFTSTGSMHGGQETTLLSMMLPLLHHGMILLGLPSSEDALRETNSGGTPYGASHVAHIQQSLSQDEKILCFALGARLAKTALKLKPHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW9</accession>
    <name>A0A1D3RMW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">30S ribosomal protein S1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_02129_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000429">
        <property type="protein sequence ID" value="SCN46994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000110">
        <property type="entry name" value="Ribosomal_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002111">
        <property type="entry name" value="RpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00717">
        <property type="entry name" value="rpsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="105"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="192"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="277"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="364"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="451"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="553" mass="61196" checksum="19AFAEF85510D90B" modified="2016-11-30" version="1">MSESFAELFEESVKQTEMRAGAMLKGTVVDIDNDKVIVSAGLKSEGVIPRWQFLNAEGDLEVAIGDEVEVALDLIEDGLGATLLSRDKAKKHQAWGDLEKAFEGEETIVGRINGKVRGGFTVAVGALRAFLPGSLVDVRPIRDTTFLEGRDLEFKVIKIDQKRNNVVLSRRAVVEKEYSAERDELLKTLEDGAVIKGIVKNLTDYGAFIDLGGIDGLLHITDMAWRRVRHPSECVEIGQEIEVKVLKFDKEKTRVSLGMKQMAEDPWHDIATRYPAGTRVTGKVNNLTDYGCFIEIEEGVEGLVHVSEMDWTNKNVNPSKVVALGDSVEVMILEIDEERRRISLGMKQCRTNPWDEFAATHNKGDKISGKIKSITDFGIFIGLDGNIDGLVHMSDISWSDTPEDSIRNYQKGDEVETVILAVDAERERISLGIKQLEQDPFQNYIAINEKGSMVKGVVKEVDAKGAVITLAEGIEGYLRASEIQRDRVEDATKLLSVGDEVEAKFIGVDKKNKSISLSIKAKDSDEEATVMKEYSEAAAGTPTMGDLFKQLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX4</accession>
    <name>A0A1D3RMX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arsenate reductase</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_38472_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000448">
        <property type="protein sequence ID" value="SCN47022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03034">
        <property type="entry name" value="ArsC_ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006659">
        <property type="entry name" value="Arsenate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00014">
        <property type="entry name" value="arsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="115" mass="13038" checksum="9252F512EB7DB223" modified="2016-11-30" version="1">MSVKIYHNPRCSKSRQTLQLLEEQDIQVEVIEYLKTPPTVDELDNILTLLDMQPRELMRKKEAEYKETGMDNPDLDRSALIAGMVNTPKLIERPIVLANGKAAIGRPPENVLAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ2</accession>
    <name>A0A1D3RMZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_11998_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000489">
        <property type="protein sequence ID" value="SCN47075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4180" checksum="C5C1BC014C1632F7" modified="2016-11-30" version="1">MGIAGFLYSKKSKGTAKGSAKSGGFLVSVKLNQVMKMMVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ8</accession>
    <name>A0A1D3RMZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_104983_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000343">
        <property type="protein sequence ID" value="SCN46878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="4993" checksum="4BF95B88E4768769" modified="2016-11-30" version="1">MGHIRFLAGIEALNGLLLIAWSASFTFLAMGNLWPQIKCCDPDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN07</accession>
    <name>A0A1D3RN07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_28573_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000385">
        <property type="protein sequence ID" value="SCN46939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="129" mass="13340" checksum="75E454B568C058DA" modified="2016-11-30" version="1">MVGDGDGNVGYGVSKAKEVPIAIQKSLEQARKNMHKVALKGDTLQYSIMSEVGAAKVFMQPATEGTGIIAGASMRAVFEAVGVHNVLAKCIGTTNPINVVRATIDGLANMNNAAQIAAKRGLSVEDITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN53</accession>
    <name>A0A1D3RN53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_89081_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000487">
        <property type="protein sequence ID" value="SCN47074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="190" mass="20568" checksum="7B8B724B42FAB666" modified="2016-11-30" version="1">MSEDKSTESGEVIENIKESVEEVVEDVKESVEEVVEDIKETIEEVADTVESAIDDAKPPLMKLKDENPKLFYGAIAGIVVILGAVFMSGGDNAKQHVSKVTYTVGQSYTLHAANALTDTTLKILKVPGQMASFDNESDVVCNAPSGTPVIARSFQDAFGTKQLFVQVEVQQEAGDCRQGVKGWTLKTNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN73</accession>
    <name>A0A1D3RN73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_66859_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000505">
        <property type="protein sequence ID" value="SCN47094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004291">
        <property type="entry name" value="Transposase_IS66_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03050">
        <property type="entry name" value="DDE_Tnp_IS66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="3">
        <location>
            <begin position="45"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS66" evidence="2">
        <location>
            <begin position="158"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="469" mass="53550" checksum="2B9D968AE93E3B7B" modified="2016-11-30" version="1">MKIDNIDVEAAVKNTQQLLEVERDISPALKSALEMILLLVMVLLNRVTLNSKNSSKPPASDPNRKKGSRKKSDKPSGGQKSHKGTTLQKIDDPDEIEVITLDRSTLPKGQYTEDGFETRQVFDIDISRVVTEYQAQRLINEKGQCFIAPFPDKVTKAVQYGNGIKAHIVYLSQYQLLPYNRIQEYFADQLGMPVSEGSIYNFNKQAYEQLAEFETISKEHLVASPCINADETGININGKRHWLHGTSNDQWTHFFPHAKRGTEAMNDIGILPRYHGILCHDHWKPYYKYDCTHSLCNAHHIRELTRAWEQDKQAWAHEMKQLLEKMNIAVNDAGGVLPHIEAEKWKVQYRELLGKAEIECPPPDKPTEVKRGRIKRSKARNLLERLIDFEEDVLRFMTQTCVPFTNNAAENSIRMTKVQQKISGCFRSTTGAEIFCRVRGYLATCRKQDVSATLAMTLVFEGKLPEFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN82</accession>
    <name>A0A1D3RN82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01797_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000517">
        <property type="protein sequence ID" value="SCN47104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="6059" checksum="345A47612D1A27C3" modified="2016-11-30" version="1">MIVYISLISTEKIQQKRQLKANNPLTHKDKTTLLLFKAFTFALMNRAFRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA7</accession>
    <name>A0A1D3RNA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_363172_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000561">
        <property type="protein sequence ID" value="SCN47162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="108" mass="12242" checksum="7A5EE37411D0A576" modified="2016-11-30" version="1">MKWVYLYRAVDSHDDTLDFMLSERRDEDAATAFFKQAINNNGFPDKVVMDKSGANYAGLANINLLPKSCKPLFGCLVTIKLAWLLGILLPPCLSFPIDRSRHPDFSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF6</accession>
    <name>A0A1D3RNF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HigB toxin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_272289_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000569">
        <property type="protein sequence ID" value="SCN47184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007711">
        <property type="entry name" value="HigB-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40266">
        <property type="entry name" value="PTHR40266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05015">
        <property type="entry name" value="HigB-like_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="92" mass="10688" checksum="6B53391FD59B40AD" modified="2016-11-30" version="1">MIKSFKHKGLQLFFDKESTAGINAAHKSKLKMRLVAIDTATSIEDINLPGFRLHSLKGNKESLWAIDVNKNWRITFEFREGDAYILDYEDYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF9</accession>
    <name>A0A1D3RNF9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="9">ETF-QO</shortName>
            <ecNumber evidence="9">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_26544_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H(+) + oxidized [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000590">
        <property type="protein sequence ID" value="SCN47221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="PTHR10617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 9" id="KW-0274">FAD</keyword>
    <keyword evidence="3 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="8 9" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="77" mass="8549" checksum="449A33A1C7F8884C" modified="2016-11-30" version="1">MLPDVDMTRYVDEADVVIVGGGPAGLSAACRLKQLANEQEKEMRVCLVEKSAEIGTLYNMDATNRATFYFVHIRNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG4</accession>
    <name>A0A1D3RNG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_349680_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000585">
        <property type="protein sequence ID" value="SCN47213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="61" mass="6917" checksum="11078A90EB18F390" modified="2016-11-30" version="1">MGLLSHLWVNSDIIPLLFPNVHKNKIMISFKGTHFPKDVILYAVFFYVRYGVSLGAPPRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ7</accession>
    <name>A0A1D3RNJ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8 9">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemE</name>
        <name evidence="13" type="ORF">BAZMOX_80513_0</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8 9">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8 9"/>
    <dbReference type="EMBL" id="FMJP01000617">
        <property type="protein sequence ID" value="SCN47251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="12">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="27"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="354" mass="39542" checksum="59A68ECC14E08D6E" modified="2016-11-30" version="1">MNELQNDRFIRALLKEPVDKTPVWMMRQAGRYLPEYRELRAQAGSFMNLCTNPELACEVTLQPLERFNFDAAILFSDILTIPDAMGLGLYFAEGEGPKFERPVRTTADIEKLPIPDPEMELKYVMDAVRLIRKNLNGRVPLIGFSGSPWTLATYMVEGSSSKTFSKVKGLMFEQPHLMHKMLDKLAQSVASYLNAQIAAGAQTVMLFDTWGGSLGTEEYMEFSLRYAQQVQSLLKTNINGQRVPAVLFTKGGGQWLEAMADTEYDALGLDWQTDIKLARARVGNRVALQGNMDPITLYANPEVIKAKVGAILEKYGAGSGHVFNLGHGILPDINPEHVKVMVDAVHDLSVKYHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL6</accession>
    <name>A0A1D3RNL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_239599_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000509">
        <property type="protein sequence ID" value="SCN47098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="81" mass="9207" checksum="330BE6C7A3D8AF25" modified="2016-11-30" version="1">MQAQYLNTPPAPLQAPKQLLTVQQMANVIPAYQGRTGSIRWQIFNSESNGLKESGSIIRHGRRILIDMDKYFSWQESNAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR9</accession>
    <name>A0A1D3RNR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative Fis-like DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_03955_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulatory Fis family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000670">
        <property type="protein sequence ID" value="SCN47330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005412">
        <property type="entry name" value="Fis_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002097">
        <property type="entry name" value="DNA-binding_Fis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01591">
        <property type="entry name" value="DNABINDNGFIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_8" evidence="3">
        <location>
            <begin position="40"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="83" mass="9216" checksum="8501C0B20542B46E" modified="2016-11-30" version="1">MSISNNTPPIPLSAQVKQAVDNYLKQLDGYDATGLHAMVLAEVEKPLFEATLQYSGYNQTKTAQILGISRSTLRKKIEQYDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS6</accession>
    <name>A0A1D3RNS6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_02209_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000557">
        <property type="protein sequence ID" value="SCN47158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004586">
        <property type="entry name" value="RecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF23">
        <property type="entry name" value="PTHR11070:SF23"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="10">
        <location>
            <begin position="74"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="PDDEXK_1" evidence="9">
        <location>
            <begin position="354"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="576" mass="66413" checksum="316D8E55786F5924" modified="2016-11-30" version="1">MQALAQPSDMALLRQALTLSWFALDGQALHKLLSDEVQLGSWLNRFQDYHLLWQKNGFMAMMLRLLSQENVRVHIAKTQNAERQITNLHHLLELIQQASLDDHLGIHKTIAWLRTEITAENAGDEQQLRLESDADAVKIVTMHRSKGLEYPIVFCPYLWYRRNTLASEKHLITCHAQGEMIADLGSDQFELHRKIAIQEELAEDLRILYVALTRAKYRCYLPWVNERSEKKPNQSAFAYLLSGEKAFADMSFAEQQASLKQLSNDYPASFSYQLIDKDNTLQGSYQVSKAEQDLSAHQQKRYLYSTWQMSSYTALSYLSLHDAPELPLDKAEETSDPTHQGTQQEPLALAKGAHTGNVLHDLLENIAFSKLALREDISERRDNTCQRYGLKVEQPEIINELLYQAVTTPLNLHDTEFTLANLDEKSCLKEMPFYLMLADFSTAEINFLLQDSPTYKALSEKQMQGYLTGFIDLIFVYQGRYYVLDYKSNALPDYHPETLIHAMREHNYGLQYWIYSVVLHIYLQKRLPNYQFDKHFGGVRYLFLRGMQANQAMSGVFSDLPDQTRLNELVAILTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU1</accession>
    <name>A0A1D3RNU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Molybdenum cofactor biosynthesis protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_05066_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the biosynthesis of molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MoaB/Mog family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000684">
        <property type="protein sequence ID" value="SCN47351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012245">
        <property type="entry name" value="MoaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013484">
        <property type="entry name" value="MoaB_proteobac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43232">
        <property type="entry name" value="PTHR43232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006443">
        <property type="entry name" value="MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02667">
        <property type="entry name" value="moaB_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="3">
        <location>
            <begin position="14"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="174" mass="18968" checksum="5C0893B1A18C7429" modified="2016-11-30" version="1">MSGNERQFLSLNIALLTVSDTRTEEEDISGKTLVERLESAGHHLFSKAIVADDIYQIRATVSSWIADEQVNVIISTGGTGVTGRDGTPEAIEPLLDKALSGFGEVFRMLSYQDIKTSTIQSRAVAGVANATYIFCLPGSVGACRTAWDSLISEQLDFRTKPCNLVQLMPRLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV0</accession>
    <name>A0A1D3RNV0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
            <ecNumber evidence="5">1.8.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">msrP</name>
        <name evidence="7" type="ORF">BAZMOX_00840_3</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51296"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51292"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="5">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MsrP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.-" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000567">
        <property type="protein sequence ID" value="SCN47178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016672">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01206">
        <property type="entry name" value="MsrP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022867">
        <property type="entry name" value="MsrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="6">
        <location>
            <begin position="94"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="232"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="315" mass="35689" checksum="46E7C522FB7DD13E" modified="2016-11-30" version="1">MLIKEKSPILSSEITDKAIFLNRRKIIKAAVGLSITSLLPSTTTAEQAKKYAQVPSGPYSTSLQVTSIEDATNYTNYYEFSTNKKDATVLAQPLKTSPWTISVEGEAEKTGEFNLEDILKNNPLEERIYRFRCVEAWSMVVPWIGFPLGVMLQQFKPTAKARFVEFTTLYNPEVMIGQRGKSLDWPYVEALRIDEAMHPLAFMATGMYDEDLPKQNGAPLRLVVPWKYGFKSIKAIVKIRFSETMPATAWNKMAAGEYGFYANVNPSVPHPRWSQSRERILGASIFTPKRKTELFNGYGEQVASLYTGMDLKKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ9</accession>
    <name>A0A1D3RNZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_45768_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000732">
        <property type="protein sequence ID" value="SCN47411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="245" mass="27708" checksum="A4E799656E8E8740" modified="2016-11-30" version="1">MLGFMLVIMLSSNYAIGDAQSDREDEIRRKALEEAERQIAAEREAARLERIRIAAIPVEEDLSIDGWGTEYTTFNYKQPCDTDDTPFVAIILNGVNRKDRLTERKGELVHFKDVSIAFDRIFDFCGAIVRPKSGLSTVVENGVEVKLRTWWMTQGTEDDNGIPVRLLADEVNAVIDIATQFLHKPVYLVLGNDYGVLTIEVLNELGDRGKIRTIGGILYVDRDTGEFTKYNVYGTIWDSEGKPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP32</accession>
    <name>A0A1D3RP32_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_32698_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000791">
        <property type="protein sequence ID" value="SCN47495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="13"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="261" mass="28762" checksum="D44FC3687496A3EE" modified="2016-11-30" version="1">MNTSDTHQVIGEVYLVGAGPGDPDLLTFRALRLMQQADVVVYDRLVSPEILDLVRRDAEKIYVGKQKNNHSLPQESINELLARLALAGKRVVRLKGGDPFIFGRGGEEIETLVQHNINFQVVPGITAASGCATYSGIPLTHRDHAQSCTFITGHLKDNIVNLNYQQLVAPNQTIVIYMGLTGLDNICASFIQYGASPKLPIALIQQGTTQSQRVIIGTLQTMPDLIKNQDIQPPTLIIIGSVVALHDKLKWFHPEDKCTYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP35</accession>
    <name>A0A1D3RP35_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6 9">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 6 9">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mdh</name>
        <name evidence="13" type="ORF">BAZMOX_00536_2</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 9">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 6 9"/>
    <dbReference type="EMBL" id="FMJP01000767">
        <property type="protein sequence ID" value="SCN47460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01517">
        <property type="entry name" value="Malate_dehydrog_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="PTHR23382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="5 6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="11">
        <location>
            <begin position="7"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="12">
        <location>
            <begin position="156"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="11"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="326" mass="35426" checksum="E05AB47C24AC5D1A" modified="2016-11-30" version="1">MKTPIVIAVTGAAGQISYSLLFRIASGELFGLEQPIILRLLEVSSVLDKLHGVVMELNDCAYPLLQKIIPTDDSKLAFKGADYAFLVGAKPRKTGMKRKDLLESNAVIFAEQGKALNAVASRHVKVLVTGNPANTNALITQSNAPDLSPSCFAGMTMLDHNRAINQLAEKCGVRSKDIKNIIVWGNHSETQYPDLHHATVKGQEAFALVDDAWITEDFIPTVQHRGGAIIEARGLSSAASAAHAAIVQMRAWALGTEGDDWVSMAVVSDGSYGIEKGLFYSFPVRVAVGGEASIVNDLKIEKFSLERMQATEQELKEERMTIRHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP51</accession>
    <name>A0A1D3RP51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_253380_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000742">
        <property type="protein sequence ID" value="SCN47426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="55" mass="6114" checksum="D8BA237658ABF420" modified="2016-11-30" version="1">MTALLYHFVNASLWLQWGLAERALNLAMWVSLGGAIYVAVLLLSGLKFRHLSAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP86</accession>
    <name>A0A1D3RP86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_241696_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000794">
        <property type="protein sequence ID" value="SCN47503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="77" mass="8754" checksum="2CD29F7AFECB88D6" modified="2016-11-30" version="1">MQTEQGLGELQVRLEKLLVQSEQAEQEQRQAGAACYEQLEQVQKAWGEEELTLKSALATTKAELAQLQPLKIRETER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB3</accession>
    <name>A0A1D3RPB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02505_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000631">
        <property type="protein sequence ID" value="SCN47277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5058" checksum="7C4BACFE3E94866C" modified="2016-11-30" version="1">MRGGGNYQTLINEALRGYIQAHNESLEVTLRKVIRDELKLVKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC8</accession>
    <name>A0A1D3RPC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_395255_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000817">
        <property type="protein sequence ID" value="SCN47551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4633" checksum="85A7CB75BAFABBC0" modified="2016-11-30" version="1">MDKSGANYAGLANINLLLILAGFATMIDICQVVWFHHVIPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD4</accession>
    <name>A0A1D3RPD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DinG family ATP-dependent helicase YoaA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_17114_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000852">
        <property type="protein sequence ID" value="SCN47595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HELICc2" evidence="1">
        <location>
            <begin position="237"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="396" mass="45050" checksum="4F00635342A493E4" modified="2016-11-30" version="1">MGMTLGSKQLGDLAQDALMEYFQDAKDMPDLRVASENLEHEVKDMRLAFGMDMTRGDWKDIENNPKITEGLVRLQEHLEALADQLEIASVRSKGLETCFKRAEELEEQFNNILHDKSGKWVRWYETHRKSFTLSLTPLDIAAEFHSFMAQHSTSWVFTSATLSVDHKFDHFSRNLGINNAKSYSWESPFDFPNQSLFYHPKGLPLPNSPEFVEEIVKVAIPVINASQGRTFFLFTSHRALQAAAKLLDKQIKYPLLIQGDKPKAILLDEFKQLGNAVLLGTSSFWEGIDVRGEALSTVIIDKLPFASPGDPVLKARMEAMEKQGRKPFFEYQLPTAVIALRQGIGRLIRDVNDRGVLLLCDPRLLKKSYGHMFLNSVPAMRRTRDIKDVEAFFAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD5</accession>
    <name>A0A1D3RPD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="8" type="ORF">BAZMOX_04315_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000822">
        <property type="protein sequence ID" value="SCN47553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="216" mass="22653" checksum="9C5A41C7BEDCB274" modified="2016-11-30" version="1">MALGLIGRKCGMTRVFLEDGTSVPVSVIQVESNRVSQVKGLEVDGYRAVQVAAGEKKSSKVNKAMAGHYAAANMTAGRGLWEFRLGDGEGEELKVGSELTVELFSNGQVVDVQGTSIGKGFAGGIKRHNFGMQDATHGNSLSHRSNGSIGMCQTPGRVFKGKKMSGHMGAEKVTTQNLTIHSIDTERGLVLVKGSIPGAKGGDVILTPAAKKKNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE1</accession>
    <name>A0A1D3RPE1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_84223_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000693">
        <property type="protein sequence ID" value="SCN47368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="12"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="370" mass="41314" checksum="E0B56CE26A2413DF" modified="2016-11-30" version="1">MKGNLAQREPERLKKWTEADLYQKIRTEFSGKPPFILHDGPPYANGVIHIGHAVNKVLKDIILKSKTLAGFDAPYVPGWDCHGLPIELMVEKKVGKAGAKVSAEVFRKACREYATKQVKMQKDEFIRLGVLGDWSNPYLTMDHQFEANIIRSLGKINTKGHLSKGSKPVHWCTDCGSALAEAEVEYEDKHSPAIDVRFEVLDEEKLFACCERMPENKGEGPLSVVIWTTTPWTLPANQGVSLNPKYEYVIIQCEKDGQKERLVLVNQLWLDATERYGMENCHVLAHCLGSALENQLLMHPFYHRKVPIILGDHVTAEAGTGAVHTAPGHGQDDYVVGQRYGLPVDNPVGDNGVFLANTELFAGEHVFYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF2</accession>
    <name>A0A1D3RPF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RepA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_84508_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000700">
        <property type="protein sequence ID" value="SCN47378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018777">
        <property type="entry name" value="Replication_initiator_prot_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10134">
        <property type="entry name" value="RPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="340" mass="39247" checksum="568E95E383A22FAC" modified="2016-11-30" version="1">MTSPLLPVRHPAKDLFICDFGEVIPKSDIASMEHPLFTLSTKPDTATRNYEHNGNTVTITPSTLGMATIHDKDILIYCVSQLMAGLNQGEITSRKVRFKTHDLLVTTNRQTGGESYKRFKIALNRLRGTTIETNIKTNGEEVIEGFGIIDSYKIVVDDRKKKRMVELEVTLSEWLYNSVIGQEVLSINNDYFRLRKPIERRIYEIARKHCGKQKQWNIGLENLHKKVGSTGSLKKFRESINHIIKHDHLPDYSAIIEGKNVIFYFKNYKGSPIIPQQQKNRPFIKPDTIEKVKRVLGRSFDVYGIESEWLQWWEQSGKPELQSPDGAFFNFCKARMEKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG5</accession>
    <name>A0A1D3RPG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_01131_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000799">
        <property type="protein sequence ID" value="SCN47512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="3">
        <location>
            <begin position="74"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="150" mass="15970" checksum="523B53B17CC484A2" modified="2016-11-30" version="1">MDIRKIKKLIELIEASDIAEIEITEGEESVRINRYTQQQAAAPVMAAPVATMTTPAASTPEVASAPAAAPEASGHVVKSPMVGTFYRSASPGSAAFVEIGTAVKEGDTLCIIEAMKILNQIEADKSGTIKQILIENAQPVEYDQPLFIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG7</accession>
    <name>A0A1D3RPG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endopeptidase La</fullName>
            <ecNumber evidence="3">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_70779_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000678">
        <property type="protein sequence ID" value="SCN47337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="4">
        <location>
            <begin position="278"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="486" mass="53427" checksum="34EE392C20C489B7" modified="2016-11-30" version="1">MAEEILDADHYGLEKVKERILEYLAVQQRVKSLNGPILCLVGPPGVGKTSLGQSIARATNRKYIRMALGGVRDEAEIRGHRRTYIGSMPGKILQNLAKIKVRNPLFLLDEIDKMSGDFRGDPASALLEVLDPEQNKAFADHYLEVDFDLSDVMFVATANTMNIPGPLLDRMEVIRLAGYTEDEKINIAMRYLVPKQLKKNGLLDSEVRITEEVIQDIVRYYTREAGVRSLEREISKICRKVVKQLLLKEKQEIVNIGSDNLADYLGVRRFNYGLAEEKDQVGQVTGLAWTEVGGEMLTIESAVMPGKGKQVSTGKLGDVMKESIAAAMTVVRARAGILGISDEAFQTQDLHIHVPEGATPKDGPSAGVGMCTAIVSALTSIPVRADVAMTGEITLRGEVLAIGGLKEKLLAAHRGGIKTVLIPHENEKDLVDIPDNVKQNLTIKPVRWIDEVLDIALQYQPEPIKKASIQAEKKGIKSKVKSVTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG9</accession>
    <name>A0A1D3RPG9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmG</name>
        <name evidence="5" type="ORF">BAZMOX_16663_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000845">
        <property type="protein sequence ID" value="SCN47591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="6057" checksum="2F0FF141529B3377" modified="2016-11-30" version="1">MRDKIKLVSSAGTGHYYTTDKNKRTMPEKMEIKKFDPVVRKHVMYKEAKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI4</accession>
    <name>A0A1D3RPI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01548_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000761">
        <property type="protein sequence ID" value="SCN47449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="314" mass="35415" checksum="7B8586A7F459627D" modified="2016-11-30" version="1">MLSLIIPVYRNEGSLPDLLIALNQLHNEMDKQIEVVFVIDGSPDRCYEILKDALPNQQYASQLLLLSRNFGSFPAIRAGLSVGNGEYFAVMAADLQEPPELVLQMSQVLQEGETDIVAAVREGRDDPILSKILSSIFWGLYRRLVVSEIPSGGVDIFACNLNFRDQLLKLEERHSSLVAQMFWLGFRRKFIGYKRQKRQHGKSAWTLHKKKNYLMDSVFSFTDLPIRLLTRVGGISTLFSGIFGLIVIAARAFGYIAVPGYTTLISLIVFFGSLNLFALGIIGSYAWRTYENTKGRPLHVVLQQFKYTPKTLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ1</accession>
    <name>A0A1D3RPJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfate adenylyltransferase subunit 1</fullName>
            <ecNumber evidence="3">2.7.7.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_02872_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.7.4" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000872">
        <property type="protein sequence ID" value="SCN47613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04095">
        <property type="entry name" value="CysN_NoDQ_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044139">
        <property type="entry name" value="CysN_NoDQ_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="165" mass="17751" checksum="8925AF64E142EA55" modified="2016-11-30" version="1">MNTPEHHDAKNLQLNEIGLCTVSVNAPVVFDAYHRSKGTGSFIIIDRLTNVTVGAGMITGSSSELELSHVSSEERAARFAQKATSIALTGKNKDSVAYQLERKLFDNGHATIVLTSHLEEAITVVKQAGLICICTADSGCDLSFDTDTLSADDIHLALKDKNIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ7</accession>
    <name>A0A1D3RPJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transposase Tn3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_17197_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000747">
        <property type="protein sequence ID" value="SCN47428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002513">
        <property type="entry name" value="Tn3_Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01526">
        <property type="entry name" value="DDE_Tnp_Tn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0814">Transposable element</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="DDE_Tnp_Tn3" evidence="6">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="297" mass="34598" checksum="51AB62B289BDAB2F" modified="2016-11-30" version="1">MARYSPKYFGQEKGVSAMTLVLNHIPVNSKIISADDHESHHIFDLLYNNTSEVKPDILSTDTHGANRYNFAILHFFGYQFAPRYKTFKNHFEKMFQVESAEDVEQLISLKVPIDWELITREWDDICRLMISLGQHKTSQSVLIKKLCRYKSNTATLKAFAEYDRAIKAQYILDYIDSETLRRHVQRTLNRGEAFHQLRRVIAETNGKKFRGSHHAELTLWNECARLISNCVIHYNAQILSELKESNEHEGRSENLEALKRISPVAWFHINFSGFYSFADSENSHDFSELARKVHLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL1</accession>
    <name>A0A1D3RPL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">[NiFe] hydrogenase nickel incorporation protein HypA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_23642_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000914">
        <property type="protein sequence ID" value="SCN47675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000688">
        <property type="entry name" value="HypA/HybF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34535">
        <property type="entry name" value="PTHR34535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01155">
        <property type="entry name" value="HypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0533">Nickel</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="73" mass="8065" checksum="35A05A8B5996FDEF" modified="2016-11-30" version="1">MPDAIRFCFDICSKDTLLEDAKLEINEIPGLGCCQSCGAEIELEEIFDLCSCGSNQITCIAGEELKIKEIEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ9</accession>
    <name>A0A1D3RPQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_179926_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000925">
        <property type="protein sequence ID" value="SCN47683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4454" checksum="BFB904AF37199E45" modified="2016-11-30" version="1">MILFYAHWEIKGGLYQNLPINATEIPQLAYACDRTLNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS3</accession>
    <name>A0A1D3RPS3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HYR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_37709_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000891">
        <property type="protein sequence ID" value="SCN47646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003410">
        <property type="entry name" value="HYR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02494">
        <property type="entry name" value="HYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HYR" evidence="2">
        <location>
            <begin position="10"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5641" checksum="ADE01695C8CA1CB7" modified="2016-11-30" version="1">MLNSILGSRDRTSPVMHCPAVPHKLADPIQTNTIVTWEEPIAQDNKDGTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT8</accession>
    <name>A0A1D3RPT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_23683_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000760">
        <property type="protein sequence ID" value="SCN47447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="6164" checksum="51E9C5723591275E" modified="2016-11-30" version="1">MKCRFDLAVKKRTVYMESKPLDEKVDSNCNCEDVKNDMNQYCDMWHKLTQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY1</accession>
    <name>A0A1D3RPY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein with LysM domain, COG1652</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01663_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000963">
        <property type="protein sequence ID" value="SCN47751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="146" mass="16315" checksum="1D9875EF83AE1861" modified="2016-11-30" version="1">MILELGDPATLRITNTEKEVRRGDRLMPSSEEEVAFNFFPTLPSELIDGSIIAVLNGVQEIGQYDIIVISKGKQDGLKQGHLLSIIQKGKVITDPFHKNKNELVKLPDQEAGIALVFRIFDRVSYALVMSASKNIRVLDRVQTPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ05</accession>
    <name>A0A1D3RQ05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_158427_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000952">
        <property type="protein sequence ID" value="SCN47734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4193" checksum="E946EF5BA6B4EA3E" modified="2016-11-30" version="1">MDKNGANYAGLVTITEVETAHMIRKRQLSEENIPAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ55</accession>
    <name>A0A1D3RQ55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein Imp, required for envelope biogenesis / Organic solvent tolerance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_57760_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000987">
        <property type="protein sequence ID" value="SCN47776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010033">
        <property type="term" value="P:response to organic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007543">
        <property type="entry name" value="LptD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04453">
        <property type="entry name" value="LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LptD" evidence="1">
        <location>
            <begin position="12"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="462" mass="53128" checksum="89158C0EBAB2E3DA" modified="2016-11-30" version="1">MMPEDKQTKTLRWGGSFQHKTQLSKELSFDWDANYVSDNAYFADLDGSLGMGNRSRYLISDANIAYTLPWMTLTAKAENYQNIDPNQDDKLVPYRRLPQVKLDMFKDFDELPIKLALDSEYVIFQRHFSDGRAEGQRLNLKPSVSFPFISEAGFITPKIALQHTQYWLGGDGPAQYSTNASKTLPIVSVDSGLFFERDFESLTHTIEPRLFYLYVPYTDQSDIPNFDTALYDFNSSQLFRDNIFNGVDKTQNTNQITAALTTRLVENGRNRLKLTVGQIFYFEDRKVNLLGNAVHSELLSNLVTELSSEITDEIKFNSAMQWSYEENAIRRGSADLSYHGIKNNTILNIGYRYRLQQVTQAAQEQITASAIIPIYDGWSIIGLYRYSFLNDKTLEYFYGIEKDSCCWRFRVIARQFMLSTSADVKPQSSVYLQIELKGLTSLGDKLENFLLENIPGYRKPNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ77</accession>
    <name>A0A1D3RQ77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-dependent DNA helicase UvrD/PcrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_47804_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000986">
        <property type="protein sequence ID" value="SCN47772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="10066" checksum="48676EC8DF64B6A9" modified="2016-11-30" version="1">MLIINSLTEQSEGAELYQQVKNAIEKSNLIEFYKKEKGDKGEARVENLEELVNAARQFDYDASNEENQSELDIFLSSCRFRIGRCTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ89</accession>
    <name>A0A1D3RQ89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_350943_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000899">
        <property type="protein sequence ID" value="SCN47658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="133" mass="16093" checksum="801641222CD8B326" modified="2016-11-30" version="1">MIAFLYHRRWDEEKYFDNYKTDMANAKAWGKSPIAIEQQALLALVTHILMRLFLNKKGQEMGLEEDHQTQQKRHEAKETAYCIDWEGNYNRAFFRKLSKITKQAWRFLKNNFLKKSATWLFERKLRPVLMAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ99</accession>
    <name>A0A1D3RQ99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_55186_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000910">
        <property type="protein sequence ID" value="SCN47668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="120" mass="13712" checksum="92C87750E53DD9A1" modified="2016-11-30" version="1">MEERGVNVDHATLNRWVIRYAPTIAAKAHSQKRNTNSSWRMDETGFALKILPFYFEKFPFLIRCLYNIFLQDVGGYSSFVASVNCLVAVYFTPMSCLNSTSVLLSVTFRGYALIIRIQVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA8</accession>
    <name>A0A1D3RQA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_22098_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001009">
        <property type="protein sequence ID" value="SCN47802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4820" checksum="170A9B0E3A881932" modified="2016-11-30" version="1">MFSFSKRLLATSDRSVLLSSTPVFSTNAVNNIERGVNVCIFIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE9</accession>
    <name>A0A1D3RQE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_324762_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001064">
        <property type="protein sequence ID" value="SCN47884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="3875" checksum="CCFC02BC5ACB302E" modified="2016-11-30" version="1">MGIRAQASGKNLTRLVNAFGVPIRPCHLAPTQQGIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQH5</accession>
    <name>A0A1D3RQH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_19223_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001060">
        <property type="protein sequence ID" value="SCN47882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5513" checksum="6EFC37E7988DD0F7" modified="2016-11-30" version="1">MGLYGGFKFVFFLQVSLSDFKPEKIKAGSRYFCESLFWVSQPKQAAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQK2</accession>
    <name>A0A1D3RQK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_28938_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001025">
        <property type="protein sequence ID" value="SCN47839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="7033" checksum="B892C59F0E515A09" modified="2016-11-30" version="1">MASVNDVLWISPYRNATSHQDLVAWGEGFNLRQSASVPAPTPVLLLMLGLLSLAIVSREKLGVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQM6</accession>
    <name>A0A1D3RQM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hflX</name>
        <name evidence="5" type="ORF">BAZMOX_29552_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001005">
        <property type="protein sequence ID" value="SCN47798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="4">
        <location>
            <begin position="99"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="105"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="130"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="152"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="218"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="244"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="324" mass="36490" checksum="096F814FB1CEB3D3" modified="2016-11-30" version="1">MVDRNGLILDIFALRAKTYDGKLQVELAQLNHLSSRLTGGWSHLDRQKGGIGMRGTGETQLESDRRLVSQRIKLVESRLEKVVKQRHQGRVRRKRSDTPGVSLVGYTNAGKSTLFNRLTGSDIYVANQLFATLDPTMRRCRLANNSEVVLADTVGFIRHLPHELVAAFKSTLQEATDADLLLHVIDASDEYRNETIYEVNRVLKDIGADKSPQLEVFNKIDLLDDFAPRIDRNDQGRPIRVWLSAQTGAGMDLLLQALEEIFSATRVRRLCHLLSSQGGVRSQLFSVANILQEDCTDEGGWDLLVEIDQQYLGILREVEIEEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQM7</accession>
    <name>A0A1D3RQM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate synthase</fullName>
            <ecNumber evidence="2">2.7.9.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_31641_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.9.2" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001048">
        <property type="protein sequence ID" value="SCN47869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PEP-utilizers_C" evidence="1">
        <location>
            <begin position="48"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="286" mass="31981" checksum="A249B607CD8096E4" modified="2016-11-30" version="1">MEFIITEYIKVHPMALLYPDKVKSSKERQEIAQLVQGYNSPTDYFVQRLSEGVGMIAAAFYPKPVVVRMSDFKSNEYASLLGGNAFEAKEENPMIGFRGASRYTHPAYQEGFELECAAMKRVRDEMGLNNVILMIPFCRRIDEGKRVLAKMAECGLRQGKNGLKIYVMCEIPNNVIQVDEFAKLFDGFSIGSNDLTQLTLGVDRDSQIVAFDFDERDPGVKAFLKMAVEGAKRNGRHSGICGQAPSDYPEMAEFLVECGIESMSLTPDTIIKTTLNVLAVEKRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQQ9</accession>
    <name>A0A1D3RQQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP synthase beta chain</fullName>
            <ecNumber evidence="2">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_140222_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.6.3.14" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001014">
        <property type="protein sequence ID" value="SCN47817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5767" checksum="7E2D86C77014524E" modified="2016-11-30" version="1">MSRGIAELGIYPAVDPLDSNSRILDPYVVGEEHYNVARSIQKILQVIIWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQW9</accession>
    <name>A0A1D3RQW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_86047_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001056">
        <property type="protein sequence ID" value="SCN47877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="200" mass="23181" checksum="600ED8F992C16BB3" modified="2016-11-30" version="1">MTLKNIFLILVIQFLTLSIAHSNEKNSFFDGTMLKIPIVDTPEHSGLYQNVEFKPLADGKWEIVGYNKREKSYEIKTVNLFLTEELPIQGFLKVTGLPKDCRRYTRLIRTQLVGDTFEVFIDSKEHYPEGTFCYKRIGLIEFTEIIPLPLYGIKSGDYKYTVNGEYQGVFNVSSDNVVEMPQSDEDDIFDPREGWDEDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RR09</accession>
    <name>A0A1D3RR09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GTP-binding protein TypA/BipA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_12411_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001086">
        <property type="protein sequence ID" value="SCN47917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFG_C" evidence="1">
        <location>
            <begin position="259"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="462" mass="51287" checksum="6DE0C6D9AB5BCD0C" modified="2016-11-30" version="1">MVDQTFDLFDNLGATDEQLDFPIIYASALNGFAGLEEDVSGGDMTPLFQTIIDKVTPPPVDVDAPFQMQVISLDYNSYVGVIGVGRIQRGTVKRNQPLTLVDAEGNTRNGRMLKIYGFSGLERVEVDSAQAGDIIAFCGIENLQISETLCHPDYVDGLPALSIDEPTVSMTFQVNNSPFAGKEGKFITTRQIYDRLQKELQHNVALRVEITDDPDKFKVSGRGELHLSVLIENMRREGYEMGVSRPQVIIREIDGVKSEPYENVTIEVEEQHQGTIMEKLGDRKGELKDMVPDGKGRIRLEYVVPSRGLLGFQTEFLTATSGSGLFYHVFDHYGAVKEGAVGNRVRGVLISMSKGKAVDYSLYPLQARGELLVVNGDEIYEGQLVGIHSRTNDLVVNPTKPKPLTNVRASGTDESLTCARIQKMTLEQALEFIADDELVEVTPESIRLRKILLTENERKRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL57</accession>
    <name>A0A1D3RL57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-deoxy-D-xylulose 5-phosphate synthase</fullName>
            <ecNumber evidence="3">2.2.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_87469_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000017">
        <property type="protein sequence ID" value="SCN46411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="110" mass="12279" checksum="A51C935B3CEA3DD2" modified="2016-11-30" version="1">MAFEAMNHAGAIDANLLVILTTTIWQSRPNVGAMNNYFTKVISSRLYSTVREESKRVLSSLPAVWELARKTEEHVKGMVVPGTLFEELGFNYIGPIDGHDLDMLVPTLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL64</accession>
    <name>A0A1D3RL64_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="6">2.2.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_87469_1</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000017">
        <property type="protein sequence ID" value="SCN46412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transket_pyr" evidence="11">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN46412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="289" mass="31303" checksum="A5D1DA3D826E04A5" modified="2016-11-30" version="1">MAEKDKRLLAITPAMREGSGMVEYSERFPKRYFDVAIAEQHAVTLAAGQACQGAKPVVAIYSTFLQRAYDQLIHDVAIQNLDVLFAIDRAGLVGPDGPTHAGSFDYSFLRCIPNMLIMAPADENECRQMLSTGYQYEGPASVRYPRGKGPGTVVNTDLDTLEIGKAEIRHQGGRIAILAWGSMVTPGLEAGKQLGATVINMRFIKPIDKDIILAMAKTHDVLVTIEENALAGGTGSAVNEFLQAQRILMPVLNIALPDAYVEQGTREELLTECGLDTQGIATSIETFCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLC4</accession>
    <name>A0A1D3RLC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ruvC</name>
        <name evidence="15" type="ORF">BAZMOX_04903_2</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="FMJP01000068">
        <property type="protein sequence ID" value="SCN46481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN46481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="166" mass="18001" checksum="4DD29427BF66ABE1" modified="2016-11-30" version="1">MARILGIDPGSRLTGFGVIDETATGYQYVASGCLRIKGDDFPLRLKQIFAGISDVVEEYQPTEMAIEQVFMHKNADSALKLGQARGAAICAVQLFDIPVFEYAARQVKQAVVGKGSADKLQVQHMVKVLLGITGELQIDASDALGISLCHSNFQQTQQRLTQGTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLC8</accession>
    <name>A0A1D3RLC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00432_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000065">
        <property type="protein sequence ID" value="SCN46472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="267" mass="31433" checksum="33B2D3F6212E064D" modified="2016-11-30" version="1">MRFRVAPVTTVEVKQNLFAPVDKIGNPENYQIETTVYSDNKNDVVISGTRLTQLHRDILDIALYHGSYKLEDEVDENMPIRTFSLHQIQKHLNHKQKNNQAWLKKKFQELKRATILIYDKDRDEDIEFNIIRVAKRSHKLGEFVLVMEELYMAFFENEISVNYKELLPSILGLKHPQTKAIVRYLLSHQSGHQINIDKLLRKIGLQGEEGNLKYYRRVVLEELEEIGDKFNIELIKTSSDGRRKNDITVKYTKHKEVQIYHPQATLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLE8</accession>
    <name>A0A1D3RLE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_16396_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000110">
        <property type="protein sequence ID" value="SCN46535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025455">
        <property type="entry name" value="DUF4276"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14103">
        <property type="entry name" value="DUF4276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="167" mass="19052" checksum="CBB45D85A1D2904A" modified="2016-11-30" version="1">MRDVLAPYMAVKGIYLHAMRIGDPGHKGGDVRFQRAQKDIKRLLQQRSDTYISTMFDYFRIDSNWSGQDVINKKIKAGGTLSVIDKASILEAETLTQMIALLPEDDIAKRFIPYIEMHEFEALLFSDATILADKINVSINQIQSILTDYKGRPEYINSDPLMPRRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLF3</accession>
    <name>A0A1D3RLF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00432_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000065">
        <property type="protein sequence ID" value="SCN46474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="322" mass="37561" checksum="88182A38EA506DE9" modified="2016-11-30" version="1">MSSEIENIRQLVTKLDEVQIDLETVQEGLEKNFENYKNISDISSDISEKNQEVLESINTLQIQATNTVEDALKKATDLKAEMSKYYSSENTKIRKDFDVLLSSIENELSTLKSTIKTSIQSAINDVNIDTSDLSHIINEKIKSIDIEPIREFTNNVNKYFEKHKNDTKEQAIEIKTIRDSIAKNKENLEKNLEEYYTEQENWIERIKNQKQRLEKSYKNTRGFLAIMIVSIFIGIGIGVIAIKYVSDKQVIIYQDLDIDKLARLSGDKKYISVRILREEMKNKETELNLLTFVPWWMILLLFLIFGMFLIPKEEEEKNNPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLI6</accession>
    <name>A0A1D3RLI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aconitate hydratase 2</fullName>
            <ecNumber evidence="4">4.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_16396_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000110">
        <property type="protein sequence ID" value="SCN46533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015933">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036288">
        <property type="entry name" value="Aconitase_B_HEAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11791">
        <property type="entry name" value="Aconitase_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74778">
        <property type="entry name" value="SSF74778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_B_N" evidence="3">
        <location>
            <begin position="14"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="112" mass="11794" checksum="2465C3884496771B" modified="2016-11-30" version="1">MTENTTNATEVLAQYREHVAERAKMGVVPQPLNADQVAAIVELIKQPPAGEEDFLLDLLTNRVPAGVDEAAYVKAGFLAAVAKGEVSSPILDAARATELLGTMLGGVIISLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM9</accession>
    <name>A0A1D3RLM9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="9" type="ORF">BAZMOX_09208_2</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000141">
        <property type="protein sequence ID" value="SCN46570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="8">
        <location>
            <begin position="102"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="217" mass="23463" checksum="064B092FEA43560B" modified="2016-11-30" version="1">MSNVFEFNAVSRVTAGTGSAKASRRNGNIPAVIYGGNNEPELIELNHNEVVKSLANEAVYSHILKLNVGGKVENAILKDMQRHPAKTQILHMDFMRVVMSEKLKLNVPLHFMNEELSPGVKEGGVVMHSMTDVEIECLPGNIPEYIEVDLTGLQIGESIHLSQLILVDGLEIIALTHGEDHDLPVAQVMKSKGASEEDAAAAEDGDSAATEEEVASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ8</accession>
    <name>A0A1D3RLQ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ParA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00589_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000166">
        <property type="protein sequence ID" value="SCN46600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="279" mass="30708" checksum="214AEA6E59B88C11" modified="2016-11-30" version="1">MGKIVTCTVHKGGTGKTTLSVALACYAVKQGLSVAIVDLDSQCNATKQFIALDQVGECLTASDLFDMTDLQTKTVCFVPHKKGDIEPDNVLHDSLDNAVKHRFSVIPANDELLSVERLPIESASIFSKNLRSLSEYFDLVVCDTPPTKGFGMLAPLMASDYAFSPINPDAFSSDGVASLFEKIRAIKEEKNKKLEFLGLVINRLNTHSPLQKQVANYMKEQLGNNVISQVIAERSAISNSAFSRRPVWYQTRSGSTRIAAKEIKNTMKILLDKMEMNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR0</accession>
    <name>A0A1D3RLR0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">BAZMOX_53815_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000155">
        <property type="protein sequence ID" value="SCN46584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="95" mass="10137" checksum="D51B79546C38B2A6" modified="2016-11-30" version="1">MNIRPLHDRVIVKRVAEETTTAGGIVLPGSATEKPSEGEVLAVGTGKVLDNGQVHELHVKVGDRVLFGKYSGSEVKIDGEDVIVMREDDIMGVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS0</accession>
    <name>A0A1D3RLS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_75130_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000162">
        <property type="protein sequence ID" value="SCN46594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="117" mass="13828" checksum="7040AF829E9733A4" modified="2016-11-30" version="1">MREILFYRTKSGECPVEDFLDTLDGKQAQKVAWEMQAVEELEQVPTTYLKKLVSTKNIWEIRVQVGNNIFRFLGFFNQGNFIVLTNGFQKKTQKTPKSEILLSEQRKQDYLERSHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY3</accession>
    <name>A0A1D3RLY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H dehydrogenase, quinone family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_121363_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000210">
        <property type="protein sequence ID" value="SCN46676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="183" mass="20810" checksum="FFD3BED1EFAE2177" modified="2016-11-30" version="1">MKILLVTAGYSIFDAKGQLNSFLAYLTEKKLSEKGHEVKISDVTKDTWSVDREVAKLLWADTIIYITPIMWFNMPAPMVKWLSEVLLYKKTFIITDEYGEGGQVPADNFMIVTTSNMKSSDLGKGFVLKDAPHIDDIMQPLIMTNTYLSIRNQIPTFHAEGVIAGDTSWIEQAYKEHLNTHFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY6</accession>
    <name>A0A1D3RLY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0276 protein BAZMOX_02676_0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02676_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0276 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000161">
        <property type="protein sequence ID" value="SCN46589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00697">
        <property type="entry name" value="UPF0276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007801">
        <property type="entry name" value="UPF0276"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42194">
        <property type="entry name" value="PTHR42194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05114">
        <property type="entry name" value="DUF692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="283" mass="32136" checksum="FB4AD1BE1FA07DFC" modified="2016-11-30" version="1">MHHTQNLVHGTGLGLRRSFLDEALASPLKNVDFYEVAPENWMTLGGKLGKQFKAMTERHPFVCHGLSLSIGSTDPLDEDFVKNLKNFMHEHKIKFYSEHLSYCSNNGHLYDLMPIPFTEEAVNHVAQRIRRVQDILEQKIAIENVSYYAAPGQEMSEIDFFNAVVEAADCDVLLDVNNIYVNSVNHNYDAEQFLQSLPAQRISYVHIAGHYVEAEDFLVDTHGADIIDPVWQLLEKAYALYGVFPTLLERDFNIPSVAELLSEVSTIQSLQNAWHTNNEQLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY7</accession>
    <name>A0A1D3RLY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_09258_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000234">
        <property type="protein sequence ID" value="SCN46715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="121" mass="13673" checksum="CC0A3A7B05F50801" modified="2016-11-30" version="1">MKSKPIDRLAVALYGMDGRTHKTMALFIQGPCKSIAQIVDEPEANVDIIDADAMDARVTLDHCLARKPLRPIIILSLEKLKIEHTIFVEKPAKTETMLAAFKEANDWLKKEKKKTTKPEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY9</accession>
    <name>A0A1D3RLY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Probable iron binding protein from the HesB_IscA_SufA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_48922_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000211">
        <property type="protein sequence ID" value="SCN46680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01380">
        <property type="entry name" value="Fe_S_insert_ErpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023063">
        <property type="entry name" value="FeS_cluster_insertion_RrpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="4">
        <location>
            <begin position="5"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="110" mass="11517" checksum="7B5744E29D86806D" modified="2016-11-30" version="1">MADPIIFSDSAAAKVGALIAEEGNDSLKLRVYISGGGCSGFQYGFTFDEEVADDDTQVENGGVTVLVDAMSIQYLNGAEIDYKEDLSGAQFVIRNPNASITCGCGSSFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM04</accession>
    <name>A0A1D3RM04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_59315_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000249">
        <property type="protein sequence ID" value="SCN46735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4046" checksum="DE58CE2C2DE9F1D6" modified="2016-11-30" version="1">MPVSSVFSSLAFIKYSISDFSSPVAFMEASSDINFHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM07</accession>
    <name>A0A1D3RM07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TrkA-N:Ion transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_18123_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000225">
        <property type="protein sequence ID" value="SCN46702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="289"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="466" mass="52945" checksum="F00143F37285D65E" modified="2016-11-30" version="1">MLTRLTLYIAYSLKTSTRYQSLKRFFYNLLKNPQSKIKPYFDIFMILLVISSVSLLLYEIEHKTSEWAILFENFVVTVFICEYLLRGWIYSDIHNLIIKQHEKTEYLGSTFHLHKVVKLIITNKLSYLFSPSAIIDLLAILPSYRPLRILRIFLIFRLFKLFRYSQSIQMFTGVLKNKRFELTTLAIFMGFLIFIASTAIYMFENQNMGGQVTDLYDAFYWAIVTVSTVGYGDITPVTTGGRLVTSALIITGLGVLAFFTSIIVAAFNEKMSEFQEERVKARIEKLTDTTILCGFGRVGQDIALQLHANKHHFVIIDNNEQHITLAKQQGYVTLFADASRNSILERAGINNGAKAVLCTTNNDITNVYITLTSRYLNPDITIISRANHEENAKKMLQAGASYIVQSFNIAGLLAAEYIGHPVAFEAIHGILHGQKDIQMEALNICGDCYLTGLSIEEANFNQPEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM18</accession>
    <name>A0A1D3RM18_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="9">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpA</name>
        <name evidence="13" type="ORF">BAZMOX_71371_0</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000231">
        <property type="protein sequence ID" value="SCN46710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="12">
        <location>
            <begin position="29"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="10">
        <location>
            <begin position="149"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="11">
        <location>
            <begin position="382"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="9">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN46710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="487" mass="52638" checksum="21416DF99C991976" modified="2016-11-30" version="1">MQLKPSEISDLIKKRIENFDVNVEAHTEGTVVSVTDGIVKVHGLSQAMQGEMLEFPGDSFGMALNLERDSVGVVMLGAYKHITEGDTVKCTGKILEVPVGEALLGRVVDALGNPIDAKGEIDAQEMSPVEKIAPGVISRQSVDQPIQLGLKSIDAMVPVGRGQRELIIGDRQTGKTAIAIDAIINQKGTGVKCIYVAIGQKRSSVANVVRKLEEHGAMAHTIIVCATASESAALQFIAPYTGCSMGEYFRDKGEDALIVYDDLTKQAWAYRQMSLLLRRPPGREAYPGDVFYIHSRLLERASRINAAEVEKLTGGKVKGKTGSLTALPIIETQGGDVSAFVPTNVISITDGQIFLESDLFNSGIRPAVNAGLSVSRVGGAAQTKIIKKLGGGIRLDLAQYRELAAFAQFASDLDESTRKQIERGQRVTELMKQDQYSPMSIAEMGVSLHAANEGFLDDLEVAKVRDFEAALQSYMKSEQADLMQKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM25</accession>
    <name>A0A1D3RM25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">[NiFe] hydrogenase metallocenter assembly protein HypE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_34263_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000248">
        <property type="protein sequence ID" value="SCN46731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011854">
        <property type="entry name" value="HypE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30303">
        <property type="entry name" value="PTHR30303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="6671" checksum="7D013C62675624B0" modified="2016-11-30" version="1">MAHGGGGRLMQQLLDDVVQPIFNNPILAQKNDSAVLPINSANIAFTTDSYVVKPLFFPGGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM31</accession>
    <name>A0A1D3RM31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_53679_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000252">
        <property type="protein sequence ID" value="SCN46741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="56" mass="6722" checksum="B18537751AC431BD" modified="2016-11-30" version="1">MAEVKKPRKKARRKRKSIAKPSLWKRLWQGLKKPLLIFWLPLLLLSLLYRLFGLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM40</accession>
    <name>A0A1D3RM40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diaminopimelate decarboxylase</fullName>
            <ecNumber evidence="2">4.1.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03539_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.1.1.20" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000250">
        <property type="protein sequence ID" value="SCN46740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="1">
        <location>
            <begin position="35"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="200" mass="22330" checksum="F286069513C4B2CB" modified="2016-11-30" version="1">MDYFNYHDNVLCAEDVAVSKIVEQYGSPCYIYSKATLERHWHAFDDAFDDAFGAQAHLICYAVKANSNLAILNTLARLGSGFDIVSLGELERVLAAKGEPKKIVFSGVGKREDEIKRALDVGIRCFNIEVKGELDRINQIAGELGVKAPVSFRVNPDVDAKTHPYISTGLKENKFGIDIDSALEEYRRAASMKNITDYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM49</accession>
    <name>A0A1D3RM49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02753_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000257">
        <property type="protein sequence ID" value="SCN46750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4768" checksum="A915CF567CC59DB7" modified="2016-11-30" version="1">MANFPVAYCGLKIITSLALRFPDFQRTFLVTWSWSEFHSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM51</accession>
    <name>A0A1D3RM51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_178809_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000158">
        <property type="protein sequence ID" value="SCN46588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="124" mass="13402" checksum="4CE2798D82C9EE27" modified="2016-11-30" version="1">MTAVGIKFLPPSRTAIAAHFGLANFPVAYCGLKIITSLSLRFPDFQRDFGATKVAGIEEISSPIKHANRLGTAQYTAPEYMLGELGSSRSDLFSLGVITYQMLTGKLPYGTQVAKTTTKAEQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM53</accession>
    <name>A0A1D3RM53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Probable membrane protein YPO2297</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_00671_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000273">
        <property type="protein sequence ID" value="SCN46771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028932">
        <property type="entry name" value="TerB-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025266">
        <property type="entry name" value="TerB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15615">
        <property type="entry name" value="TerB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13208">
        <property type="entry name" value="TerB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TerB_N" evidence="2">
        <location>
            <begin position="86"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="TerB" evidence="1">
        <location>
            <begin position="497"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="TerB_C" evidence="3">
        <location>
            <begin position="628"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="757" mass="84826" checksum="B8B9C24AB53CD627" modified="2016-11-30" version="1">MGFWLLIGGAIILYYAIKAMTKSSKQQAHKNDRQSSENEIRVTLTTSNRAVTNSNLDDDDLAAFSISYGYDEEKSKNKTQGKWIKPGKSITIKGQTFSSGNFYFGGKLSSLDGYGTEASLVDDSLKVENKPSSFKDESLDYWPKFISLTPKGRGAFLSWLSSNRSDPEIPLGYVFIYFYGLERRIAVDSIHQTVDDAEFKSLFDEILRLKGIYGSSRSFLNYSTRLLEFMCLLRPHVVSHPELEKSPQRDSLLFKHRLATTVSEEKPVPAELALAWVRFYPDYNLKKPARRCGYEFSQMFTRLYSKKYGEGIVVKPNKTRLRIEYHPASSSLRGISFPQKDLPDPSNLKGPTNKLIAIADECTTKLDAYSRYLAKPGACRTDIEAVLLLPDELGYIGNALGLAGFKKWADNAISTKNGLVNVEEFWTYTKLPLPVKINKKEAELIQNLAQKSGYGLAPDTRYHHTKTSADGKLVLFPEGHGKYFEPSKAFSEMGMVLRLGAMVATIDSHVDQSEKNLLTQFIDHDTNLSPTEKQSLHAYLLWRLNTPSNVTGLKARVGTLGKTEKVAVSRILVEVAMADGKIDPDEIKQLEKLYTLLGLDKALVTGDIHGMSSRKASLRPVSTQSEDILPASTAFQLNESILAIHESETKDVQSMLGAIFMENESTGEPYETSKDSAAVEEEFGIDKYHYALFESLIRKDKWTREEVEVLCRDSGLMVSGALEIINDWSFDKVDEAVLEEDGDAIYVDQEIVEEIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM62</accession>
    <name>A0A1D3RM62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CbiA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_133503_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000285">
        <property type="protein sequence ID" value="SCN46785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="211" mass="23593" checksum="FBF63EC2713ECCAE" modified="2016-11-30" version="1">MIISCANIKGGVGKSCLAQNIAVALLKRRKRVYLVDADSQETTADWIEERRDNPDLENIRFAKLTGKIREELLSIEEQFDIVVVDCGGHDSDTMRWALSASTHVLIPFRPKRRDLKLLPVMADLIDLITPVNPDCKFSAVITQAPTLPSQVKRILEAKEACKSFNINTLNTVIFHRNIYDDADESGSTVIEETESKATNEIKALINELLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM86</accession>
    <name>A0A1D3RM86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation elongation factor G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_74228_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000147">
        <property type="protein sequence ID" value="SCN46577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFG_IV" evidence="4">
        <location>
            <begin position="333"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="EFG_C" evidence="3">
        <location>
            <begin position="453"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="545" mass="59447" checksum="D37B9AF713C5F4AF" modified="2016-11-30" version="1">MVAQIASRLAGHPVVMQIPVGSEDEFSGVVDLLKMKAIYWRSADMGMAFTEEEIPENLQETAMEWREKLVEAAAEANDDLMEKYLDSGELSLTEIKSGLRLRALANEIAPVYCGSAFKNKGVQNVLDGVIEYLPSPAEVKPIIGHDESGGELVRKASDNEPFSALAFKIATDPFVGVLTFFRVYSGVLQSGSVVYNVLKGKRERVGRLLQMHANSREDIVEVRAGDIAAAVGFKDVTTGETLCDEGAKTNFRRKLDFPEPVISIAVEPRTKADQDKLADALDRLAKEDPSFRVASDEESGQVIISGMGELHLEIIVDRMKREFGVGVNVGSPQVSYRESIKGSIEQEGKFVRQSGGKGQYGHVVLKLEPMELGSGYSFVNKIAGGSIPKEYISAIDHGIQEQMKNGVLGGFPVVDVMVTLLDGSYHDVDSSEMAFSIAGSMAFRDGTKRAKPVLLEPIMKVEIMTPEDYMGDVVGDINRRRGIVLGMDDTPTGKTINCEVPLAEMFGYATDLRSATQGRATYSMQFEKYNETPANVASAIIDKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM92</accession>
    <name>A0A1D3RM92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_28364_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000275">
        <property type="protein sequence ID" value="SCN46773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="4858" checksum="F5FDDFF38BD900B1" modified="2016-11-30" version="1">MDSATVVTTSGVLTLFLAAVAAAIDVDLFRLDGRLSCAENAPRKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA4</accession>
    <name>A0A1D3RMA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_05516_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000279">
        <property type="protein sequence ID" value="SCN46776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="194" mass="20188" checksum="CDFA7EA8734614AD" modified="2016-11-30" version="1">MPAISAKNNTPPCARSNNPGYTTPSSSLPKNSTAAFSGAILPTDTSTKGPALRPLCACKKRAYNSLPVPLSPTNITLVSCCAKRFNCSLIRSAKALRPIGSCTANNCCFKPAFSRSNICASIARSTTNNNLAKDKGFSKNSYAPNLVASTAVSIVPCPDIIITGVTNSAFSVHSFNSVIPSVSGIQISNKIKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB5</accession>
    <name>A0A1D3RMB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UspA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_28787_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000287">
        <property type="protein sequence ID" value="SCN46786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006276">
        <property type="entry name" value="UspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="4"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="110" mass="12327" checksum="BB9C296AB09AD984" modified="2016-11-30" version="1">MNNYQHILLAADFSEHGEAVAQKAHYLATKYNAKLSVIHIVDYLPITDAAYGPVIPFDLDLNEELMNTAKKRLADMAKKLSIPADRQFLEMGSTAIEIVETAEEQHADLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB7</accession>
    <name>A0A1D3RMB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01705_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000295">
        <property type="protein sequence ID" value="SCN46803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06260">
        <property type="entry name" value="DUF820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="194" mass="22538" checksum="0A829FC2A0ED37D2" modified="2016-11-30" version="1">MATELHEKLISVDEYLHDELVRDIKYELVDGAIYAMAGASANHERISGNVAAEFRSHLKKTPCESFSSDMKVKVGSRFFYPDVLVDCHFDESKPYYTESPVIIVEVLSKSTRRMDETTKLMSYINIPSLQEYVLIEQDFVDIEVVRRSEGWQPRHYFLGDQVHFEAINLTLSVEEIYSRVKNEDMLEFLVQKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB9</accession>
    <name>A0A1D3RMB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane lipoprotein OmlA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_00299_6</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00925">
        <property type="entry name" value="OM_assembly_BamE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026592">
        <property type="entry name" value="BamE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037873">
        <property type="entry name" value="BamE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007450">
        <property type="entry name" value="Lipoprotein_SmpA/OmlA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37482">
        <property type="entry name" value="PTHR37482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04355">
        <property type="entry name" value="SmpA_OmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SmpA_OmlA" evidence="4">
        <location>
            <begin position="30"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="15959" checksum="425827E028BCD3D7" modified="2016-11-30" version="1">MLLISFSITTACSTLAVDVPFVYKIDIDQGNVIDQLMINQLRPNMTKRQVIYVLGSPLLIDPFTTNRWDYIYSQQPGHEDRVQERVALFFSGDNLVHIEGDLAPEANPPPPPPKEITIDAPKRELKKTLYEIIVGLFTFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC6</accession>
    <name>A0A1D3RMC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_172123_1</name>
        <name evidence="2" type="ORF">BAZMOX_454876_0</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000304">
        <property type="protein sequence ID" value="SCN46813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000418">
        <property type="protein sequence ID" value="SCN46974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4786" checksum="520B607B109AE952" modified="2016-11-30" version="1">MMGFKAFHSAQATIAGIEAAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC9</accession>
    <name>A0A1D3RMC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01466_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000330">
        <property type="protein sequence ID" value="SCN46855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="98" mass="11490" checksum="F6BFC5F002AE518B" modified="2016-11-30" version="1">MDQGCLLARIHYKTDRPNIMYMLLPTDEAGKRKYIHVGVDSDKQQQAIAKVSRYEERETVRRQIRLLHELYDQCHLQLSAMLNQLRCDINQVTGNTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME7</accession>
    <name>A0A1D3RME7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_47467_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000308">
        <property type="protein sequence ID" value="SCN46816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="53"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="138" mass="14553" checksum="880D2A8CF5FFB8F3" modified="2016-11-30" version="1">MFSRNNSELAQTNATEGAAFLAENATKEGVITTASGLQYTILTDAEGDKPNATSNVTVHYKGTTLDGAEFDSSYSRNAPATFPLNRVISGWTEGVQLMSVGATYRFFIPSELAYGAQGAGGAIGPNATLIFDIELLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF1</accession>
    <name>A0A1D3RMF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04905_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000327">
        <property type="protein sequence ID" value="SCN46850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="59" mass="6664" checksum="BFC93596D4FCC3F1" modified="2016-11-30" version="1">MQVLEFESQSVVRNFICCANQYSYDLSDILIAQSAVVANCATALTFDKKASRFELFTMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMH1</accession>
    <name>A0A1D3RMH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Outer membrane protein and related peptidoglycan-associated (Lipo)protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_01466_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000330">
        <property type="protein sequence ID" value="SCN46854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039567">
        <property type="entry name" value="Gly-zipper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13488">
        <property type="entry name" value="Gly-zipper_Omp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920254" evidence="4">
        <location>
            <begin position="25"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="5">
        <location>
            <begin position="111"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="230" mass="24365" checksum="44EE90032E9C8E07" modified="2016-11-30" version="1">MKKIFVVFLLNVFLLSGCATLNNATHSTDPVTGEKKVNNTTKGVGYGAAGGAALGAIIGAIAGGGKGAALGAGIGAGAGALIGGGSGYYMDSQEKILREKLEKTGVRVVRQGQDIKLIMPANVTFEVNSSTINQHFYETLNSVALVLNEFGNTRLKVFGFTDSQGSFEHNQLLSEDRARSVSSYLIHQGVNPSRLYVQGMSERFPIASNSTRDGRALNRRVELSIEPVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMH4</accession>
    <name>A0A1D3RMH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribonucleotide reductase of class II (Coenzyme B12-dependent), alpha subunit</fullName>
            <ecNumber evidence="1">1.17.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02006_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.17.4.1" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000332">
        <property type="protein sequence ID" value="SCN46863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="227" mass="25912" checksum="65A9A9C9072F6ADD" modified="2016-11-30" version="1">MTIKIDKKIVSYKVVTPEDKKPAVVEEVKNDLESMHEKLTRPEMLLGSTYKIKTPQSEHALYITINDMFLNAGTEHEERRPYEVFINSKNMEHFQWVLALTRVISAVFRKGGDITFMVEELKAVFDPKGGYFKKGGVYMPSLVAEIGHAIEQHMKHIGMLKDIELEAHQKQFLAEKRKEFEEKHGAQADESDNFPEQAQLCPKCQTKALVLMDGCMTCLNCGDSKCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMH8</accession>
    <name>A0A1D3RMH8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1863 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_224472_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000344">
        <property type="protein sequence ID" value="SCN46880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015032">
        <property type="entry name" value="MTH538_TIR-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08937">
        <property type="entry name" value="DUF1863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1863" evidence="1">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="16116" checksum="ACE940905F1D2A98" modified="2016-11-30" version="1">MAKKKVFVSFDYDNDKHYKALLKAWDANPKFDFYFSDLSSNEINSSLVSVVKQALSRKINEANYTLVLVGKEANKQHKDYKDIGYKNWLNYEVAKSKEHKNKLVGVKLSSTNTSPDELLNSRAKWAMSFTQGSIIKALEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML7</accession>
    <name>A0A1D3RML7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_02486_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000370">
        <property type="protein sequence ID" value="SCN46922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="460"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="577" mass="62475" checksum="5573D417AE2AFF1B" modified="2016-11-30" version="1">MALAQTSNKVNTYFPISIWLKNYTRSDLNGDIFAGIITAILLVPQGIAYAMLAGLPPQVGLYSSILPPLMYAILGTSRSLSVGPVSIAAIMIASFLAAPEITALGGTVENAIILAAEGGCILLIMAILRMGGLVNFISHPVLTGFTSGAAILIVLSQIRHLLGLAKNPCGFNLACQSEYFQQLNHYTVGLSLFSIIVLVLFGAPLTALLKRFKVKQNLIIGLSKFAPLLAVISTTLLVQFYQLSDLHNVAIVGVIQPGLPDISFAFFTNITQWQALLPGATFIAIIAYVESVAIANVTANLRNQKIDPNQELIGLGVANLATAFSGGMSVAGGFSRTMVNFTAGARTQMAMLIAVVLLSIAVMFFTEQFTYLPKAALASVILIAIFPLIKLREIISTWKYDPGDGIAELITLLGVLALGIEEGIALGVIITILSYLRRTSHPHIAVVGRIKETEHFRNIKRHQVETWKNLLLIRIDENISFANVSYIIDFIEDETINNSALKHVVLIFSSVSYIDSTAFEALENLIRSLNNKNILLHLAEVKGPVIDKLKQTSFLDQLGPGEIFFQTIEAVEKLGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN0</accession>
    <name>A0A1D3RMN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03068_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000379">
        <property type="protein sequence ID" value="SCN46932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021732">
        <property type="entry name" value="DUF3301"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11743">
        <property type="entry name" value="DUF3301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="88" mass="10339" checksum="CDDAD7FF9844A1C0" modified="2016-11-30" version="1">MYWQSAQKVKEIAWVATQKHCQDLDLQMLDGYIAFSGFTLKKDNRSQWHIARTYLFEFSSTGAERYNGVISMLGRRVQSIQLDPHRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP2</accession>
    <name>A0A1D3RMP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_309208_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000383">
        <property type="protein sequence ID" value="SCN46933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012440">
        <property type="entry name" value="DUF1641"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07849">
        <property type="entry name" value="DUF1641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="60" mass="6620" checksum="B8944CB730CF12D0" modified="2016-11-30" version="1">MALGWTGGNVVRMANAQTEALEKPPGLFSLMSSLNDPDARRSLHFFIGAMRIIGRQMKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMU1</accession>
    <name>A0A1D3RMU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroA</name>
        <name evidence="9" type="ORF">BAZMOX_02129_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000429">
        <property type="protein sequence ID" value="SCN46993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="9"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="25"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="96"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="439" mass="45909" checksum="E88AD5454ED467AC" modified="2016-11-30" version="1">MTQSITFTVQPGGHLRGEARVPGDKSISHRSIMLGSLAEGITHVSGFLEGEDALATLRSFQAMGVEIEGPINGNVTIHGVGLDGLTAPKDPLYLGNSGTSMRLLCGLLAGQKFDAVLTGDESLSGRPMKRVIDPLSQMGAVIESADQGRAPLTIRGQAGLHGIHYDMPIASAQVKSCLLLAGLYAEGVTSVIEPAPTRDHTERMLVGFSYPVKKEGSQVSISRQGKLTATDIDVPSDISSAAFFLVGASIAPNSDLTLKHVGVNPTRTGIIDILKLMGADIELSNQRTVGGEPVADIRVQSAQLKGIAIPENLVALAIDEFPVIFVAAACAEGETVLTGAKELRVKESDRIQVMADGLKTLGVNAKPTEDGMIIQGGVIGGGKVISHHDHRIAMAFAIAGLRANDAILIDDCANVNTSFPGFVTLASQLGLDISSEEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN09</accession>
    <name>A0A1D3RN09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01117_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000457">
        <property type="protein sequence ID" value="SCN47034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="84" mass="9009" checksum="E46A6FE07CE3C457" modified="2016-11-30" version="1">MNLLVRNIARTLTEAELLALFEPYGSIQSCTLVMNKESGLSKGFGFIEMPKVGEAKAAILGLNGKDVGGSKLRVKKAEIKQAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN17</accession>
    <name>A0A1D3RN17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01638_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000388">
        <property type="protein sequence ID" value="SCN46949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4580" checksum="278DC238E4D13410" modified="2016-11-30" version="1">MLPIFFIFHIGFAILTKKDPYFFDVFKFAMKAPRRLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN21</accession>
    <name>A0A1D3RN21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD-40 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01466_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000330">
        <property type="protein sequence ID" value="SCN46857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="315" mass="34383" checksum="CCB737B04C2BC20F" modified="2016-11-30" version="1">MKKALIVGINDYPNSPLNGCVNDANAVRTLLESHGDGSPNFGVKMMTSPSTSVTRSTLREAIENLFSSDSDMALLYFSGHGYIKSTGGYLVTTDAKKYDEGVSMDEVLAIANESKAKNKVIILDCCHSGALGSPNISGNDIAQLAEGLSVLTASRDSEYALETNGSSVFTSLVVDALKGGAADIRGNISPGSLYAYVDEALGAWDQRPIFKTNVSSFTPLRKIPPKIPFETIRKITKYFLTPDSEYFLDPTYEDTEPTAVEENIKIFKDLQKFQSVGLVVPVDAEFMYFAAINSKSCRLTALGYQYWRLVNEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN28</accession>
    <name>A0A1D3RN28_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribH</name>
        <name evidence="8" type="ORF">BAZMOX_02217_4</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="4 7"/>
    <dbReference type="EMBL" id="FMJP01000520">
        <property type="protein sequence ID" value="SCN47115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="59"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="83"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="88"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="158" mass="16706" checksum="66977C26A008D630" modified="2016-11-30" version="1">MSAVKTVEGNFLAQGGKYCIVASRFNSFIVEQLENGAIDALVRHGVNKEDITVVKAPGAYELPMVVQRIAASKKYDAIITVGAVIRGATPHFDYVSGECVKGIAQISLQYDIPVSFGVLTVDSIEQAIERAGTKAGNNGASAALSAIEMVTLFKNLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN30</accession>
    <name>A0A1D3RN30_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1863 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04389_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000477">
        <property type="protein sequence ID" value="SCN47054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015032">
        <property type="entry name" value="MTH538_TIR-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08937">
        <property type="entry name" value="DUF1863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1863" evidence="1">
        <location>
            <begin position="12"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="189" mass="22319" checksum="6F6634A58003FD0D" modified="2016-11-30" version="1">MSLLYGHNQPRHKVFVSYHHANDQCYRNYFEDIFSNMYDIMVSKSVQIGDININLQTDTIRQKIRDEYLRDSTVTVVLVGSETWKRKHVDWEIGASIRATQFNPRSGLLGIILPSYQRPYNEPNKYLRNTIPPRLHDNIECGFAKIYGWSNNPSEVQSWIHDAFQRRNNINPDNSYPFFVNNRSGGRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN36</accession>
    <name>A0A1D3RN36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">6-phospho-3-hexuloisomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_20256_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000504">
        <property type="protein sequence ID" value="SCN47092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5591" checksum="8D22F4037FE33FFA" modified="2016-11-30" version="1">MYDKVKGMPMGTVFELSTLLFLESTISHIIHEKGIPEEIMRERHANME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN56</accession>
    <name>A0A1D3RN56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Riboflavin biosynthesis protein RibD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="7">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="7">DRAP deaminase</shortName>
                <ecNumber evidence="7">3.5.4.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">Riboflavin-specific deaminase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
                <ecNumber evidence="7">1.1.1.193</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="7">HTP reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_02217_1</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 7">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 10">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="7"/>
    <dbReference type="EC" id="1.1.1.193" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000520">
        <property type="protein sequence ID" value="SCN47112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006769">
        <property type="entry name" value="RibD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="11">
        <location>
            <begin position="7"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="300"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="367" mass="39711" checksum="096696B3E7F88E8A" modified="2016-11-30" version="1">MAKQQAEQDSLFMARALYLAKKGRYTTKPNPRVGCVIVKGNEIIAEGWHMRAGQGHAEVEALKNTQEAQGATAYVTLEPCSHYGRTPPCAEALIRAGVVRVVIAMQDPNPLVAGKGVALLEQAGIDVVCGVLESEAQALNKGFITRMTTANPYVISKMAMSLDGRTAMASGESKWITAPQARHDVQKLRAASCCVLTGVDTILADDPSMNVRLEGVDVVQPLRVVLDSQLRTPISAKLLTLAGRTLILTCSEEQHKFEALTQAGAEVYKIARNKQGRLDLNAVLLFLAEQQVNQVLIEAGAVLNGALMEQNLIDECIVYMAPCLLGSSGRGLFDMPDITVMADKKNLTLLEARKVGVDLRLQYKVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC0</accession>
    <name>A0A1D3RNC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_165749_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000539">
        <property type="protein sequence ID" value="SCN47136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="64" mass="6844" checksum="DB6399F38C3D8792" modified="2016-11-30" version="1">MNTATKIPGLPALTADFLQSSDCLVDNLFADLWKSMGMNALLSKAGGSVASISESEECLVFRYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND0</accession>
    <name>A0A1D3RND0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="4" type="ORF">BAZMOX_00434_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9675" checksum="811647BBECB002AF" modified="2016-11-30" version="1">MVVIRLARGGQKNRPFYHVVVTDSRNSRDGRYIERLGYFNPLARGSEERLKLDEERIAHWRANGAQPSERVAKLIKDAKKAAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND7</accession>
    <name>A0A1D3RND7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01012_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000580">
        <property type="protein sequence ID" value="SCN47201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4076" checksum="76F53EABDEE0C625" modified="2016-11-30" version="1">MIGQIKIDHNIRVLVVCQVSPRCTMILHAALLSLCSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE3</accession>
    <name>A0A1D3RNE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_218857_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000576">
        <property type="protein sequence ID" value="SCN47192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4347" checksum="97889AAEC9756975" modified="2016-11-30" version="1">MIDKALTVPKEKVGQVIGRLNKQKVTEINRLLAIFLGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF5</accession>
    <name>A0A1D3RNF5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_00840_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000567">
        <property type="protein sequence ID" value="SCN47176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="335" mass="36572" checksum="735042888D971B54" modified="2016-11-30" version="1">MTIKIAINGFGRMGRLAFRTAWSWPEFEIVHINENAGDAATAAHLLNFDSVHGRWEHVADSDNNKLTINGQSISYSQNTALEDTPWHELGVDIVVECTGKFKSKEALAPYLNQGVKKVVVSAPVKDGTLNIVMGANDHLYDPKVHQIVTAASCTTNCIAPIVKVIHENFGIKHGSITTIHDMTNTQSILDEYHKDLRRARASSLSLIPTSTGSATAITEIFPELKGKLNGMAVRVPLANASLTDCVFEVEQPVTVEVVNAALEAAAMGELKGILGYETKPLVSADYTNDTRSSTVDALSTMIINGTQVKILTWYDNEMGYVQRMMELTKKLAQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH5</accession>
    <name>A0A1D3RNH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)HX epimerase / NAD(P)HX dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_36377_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000577">
        <property type="protein sequence ID" value="SCN47196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="107" mass="11083" checksum="070689E22EF7DF7D" modified="2016-11-30" version="1">MQLFSAVGEGKLSGDAALAQQSYMAAGGVILHNLQLLSHHADLIIDALLGTGLDRPVIGKFAAVIQTINSIDSPVLAVDIPSGLNADTGNIMACAVHADFTITFIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK0</accession>
    <name>A0A1D3RNK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00619_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000609">
        <property type="protein sequence ID" value="SCN47243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032585">
        <property type="entry name" value="DUF4912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16258">
        <property type="entry name" value="DUF4912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="180" mass="19876" checksum="EECA0A535053825D" modified="2016-11-30" version="1">MTFWQSRYNPQLKLSQQDLIDISEEITQAYAPDNSYVQSELVLMPVDPVTLHAYWNIQNNSTSATDTELILRVYSEPILSEHSSHLRLSFDIKLSSFQGQQTVAAPMAATAYSAVIGTINADSSFSVLATSEIIHVPRESPAPTHNTVLNAPNIDPVSVNVSAGDEHTYVMEQKNLQSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM4</accession>
    <name>A0A1D3RNM4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="7" type="ORF">BAZMOX_04234_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000632">
        <property type="protein sequence ID" value="SCN47280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9097" checksum="4A80E64440D20C0E" modified="2016-11-30" version="1">MAHKKAGGSTRNGRDSNANRLGVKRFGGETVTSGSIIVRQRGTRFHPGTNVGCGKDHTLFATTDGQVVFEVKGPKKRKFVSILAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ6</accession>
    <name>A0A1D3RNQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_239599_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000509">
        <property type="protein sequence ID" value="SCN47097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="105" mass="12233" checksum="F42D01D2335A51D7" modified="2016-11-30" version="1">MMNKSIDKKHLNDWLLEAWGNHPIISEQQQENFKQCFHKAKTYSQAVKIDLLIEFIDRVKLLKQEIMATSDINKIELNMDAIKVIEFKQNMLAAIIGECNQEASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR6</accession>
    <name>A0A1D3RNR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HigA protein (Antitoxin to HigB)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_72607_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000551">
        <property type="protein sequence ID" value="SCN47148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013430">
        <property type="entry name" value="Toxin_antidote_HigA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36924">
        <property type="entry name" value="PTHR36924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02607">
        <property type="entry name" value="antidote_HigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="101" mass="11367" checksum="25DCFF16FE58C470" modified="2016-11-30" version="1">MTIRQYNPPHVGGLIYRTYIEPFDNISANSVAKSLGVACSTFNRLLNGISNLSPEMAIRLSTVLGGSAESWMRLQETYDLWEARKKVDTKKLSRIDFDQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS5</accession>
    <name>A0A1D3RNS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01012_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000580">
        <property type="protein sequence ID" value="SCN47199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="173" mass="19473" checksum="B14C5E607E819748" modified="2016-11-30" version="1">MASSGMFTNFAQFYMDLEFDDLDLFMITRKFHIGNIEGKLSGVVQNLYLENWQPVSFYAWMGTPEGDDSTHKISQKAVENIASIGGNSAADVLSKGFLSLFSSFRYDKLGFGCYLHQGVCQLMGVEAVDNGFYLVKGGGLPRINIIGYNPRLNWSVLLERLRRITKSDEFIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS9</accession>
    <name>A0A1D3RNS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Isocitrate dehydrogenase [NADP] Monomeric isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="1">1.1.1.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_45301_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.1.1.42" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000696">
        <property type="protein sequence ID" value="SCN47375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004436">
        <property type="entry name" value="Isocitrate_DH_NADP_mono"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36999">
        <property type="entry name" value="PTHR36999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03971">
        <property type="entry name" value="IDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="564" mass="61729" checksum="AC9114DF47A3B583" modified="2016-11-30" version="1">MTDGDFYGNEKSIVIKEAGNVTIEFLDTSGATRVLKQNTPVLAGEILDASVMSCSALCAYFEQEMQTAKAEDVMLSLHLKATMMKVSDPIIFGHAVDVYYQEVFAKYADTFESLGINTRNGLGDVYAKITNLPDEQRLAIEADIQAVYQSRPALAMVNSDKGITNLHVPNDVIIDASMPATIRFSGKMWGKDGQLHDTKALIPDRSYAGVFQATVDFCKQHGAFDVTTMGTVSNVGLMAQKAEEYGSHDKTFEIPAQGSVRVTDKAGNILLEHKVEAGDIWRMCQTKDLPIQDWVKLAVTRARLTGLPAIFWLDNKRAHDANLITKVETYLKDHDTHGLTIKIMAPIEAINYTLLRVQAGEDTISVTGNILRDYLTDLFPILELGTSAKMLSIVPLLAGGSLFETGAGGSAPKLVEQLLAENHLAWDSLGEFLALAVSLEDLAEKTHKPSIKALANALNKANSLYLNNNKSPSHTIGAGDTRSSHYYLTMYWAQSLAEQTEDKALQAKFIPIAQQLSDNENKIVTELSPTHVGHVDIGGYYLPNKELVEQVMRPSACFNAIISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV5</accession>
    <name>A0A1D3RNV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_15154_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000694">
        <property type="protein sequence ID" value="SCN47370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="301" mass="34136" checksum="5724419EC65FD300" modified="2016-11-30" version="1">MNGFMDSPQADNQFFKQVVSPYREMAAYEALWEKRSATYKRIADMFKERPGAIPSDLVEPEAVEKIMRTLGDIFHKYNLDTFGVRVRGANEYPESLRDAKNPLEVLYYQGLWGLVNTSSVAIVGARKVSSEGVRRTRKLVKCLVEDDFTIVSGLAEGVDTVAHTTALEMNGRTIAVIGTPLTHIYPQNNLELQVIIKENHLLISQVPFKRYLDQDYRSNRSFFPERNITMSALTQATVIVEASDTSGTLYQARAALAQGRKLFILDSCFKNPHISWPERFSKKGAIRVKGYEDIKEHLEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY8</accession>
    <name>A0A1D3RNY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00412_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="59" mass="6684" checksum="C6B7C78CEC638C2C" modified="2016-11-30" version="1">MRILLVSDIFFVMGFGLVDLRGYQAIHLTRNKFSPSLKLYDKALLVLKGLAGLLEVIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ3</accession>
    <name>A0A1D3RNZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_09742_3</name>
        <name evidence="2" type="ORF">BAZMOX_392946_0</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">BAZMOX</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FMJP01000759">
        <property type="protein sequence ID" value="SCN47445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000932">
        <property type="protein sequence ID" value="SCN47705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4292" checksum="72369EED661DC113" modified="2016-11-30" version="1">MPPSRTAIAAHFGLANFPVAYCGLKIITSLALRFPDFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP16</accession>
    <name>A0A1D3RP16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">21 kDa hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_41472_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000778">
        <property type="protein sequence ID" value="SCN47475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="43"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="1">
        <location>
            <begin position="121"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="197" mass="21521" checksum="0364A1EB377A5A3D" modified="2016-11-30" version="1">MKLSLVLFFIFSLTGCGSLANGLAELTGLSFLHDRRSSAVIALDENIEDSAIIELHALDDVKEHAHFNVTSYNGKVLVTGEAESEAIRDKIIANIRIISGVKLVHNEMVIAPISTMQSRSEDALITIKVKDALTKIKGKPGFDATRVKVITERKVVYLMGIVHEEEGLAAAKVVQSVPGISKIVTVFEYIDYAKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP17</accession>
    <name>A0A1D3RP17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus biogenesis protein PilZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_125779_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000749">
        <property type="protein sequence ID" value="SCN47431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="117" mass="12701" checksum="A8F2232E0713F59A" modified="2016-11-30" version="1">MAEPSAARQGILSLSIKEKNALYAAYMPFVANGGLFIPTNRSYTMGQEVFMLLNLMEETERLPIAGKVIWITPVGAEGYRTAGIGVQFSDQDGGQARNKIETYLAGTLESGRSTHTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP22</accession>
    <name>A0A1D3RP22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_06368_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000636">
        <property type="protein sequence ID" value="SCN47289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4367" checksum="D351EF00B46DF46C" modified="2016-11-30" version="1">MRELEVLELSALTISEAMAHYQNLYQEKAQQATLRASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP23</accession>
    <name>A0A1D3RP23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS2020, hypothetical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_54647_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000786">
        <property type="protein sequence ID" value="SCN47485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="6993" checksum="3EAA8E0D13AB735D" modified="2016-11-30" version="1">MNNIIEQDHRFIKKITKPMMGFKAFHSAQATIAGIEAAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP37</accession>
    <name>A0A1D3RP37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01548_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000761">
        <property type="protein sequence ID" value="SCN47451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025686">
        <property type="entry name" value="Glucos_trans_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14264">
        <property type="entry name" value="Glucos_trans_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="706" mass="79922" checksum="11A363D73D902CF7" modified="2016-11-30" version="1">MPIWLKSKLLNFAITFVFIFSFMAITIDEKIYMEVTSSVAGLTQFFYSSKEGDFAENKSSVSSLQIGENKLTAHFLLQTKFIRWDPVNGSGEFNIKALYVKILFFDIIIPYDDIAANFDIECIVKYPNEISILTSDGSLDPSILIKLPQGKILSIYLLTSLILAAIIFTVILFLSENHRKLKKLHTRLSTKIYDERAFFKKLPLLISIACLFWIFSLTGYSISIDDEFAMFRQDHSPWIAQGRWAVFLLTEFILPQPIIPFLPHFIFCVSVSVSYLILVRAHGMELSWKNIALFPIFMAFPTWYFIAGFYANIPAVSMGLIFTSITLLIFSHSLSKINEWKILDKTFFLLIFIQAFILSIAIGCYQSYIFCFLSMGLGIILLKVDQNSSISNRYIIRSLGYLFLIVCASLLLYYSTDFTFKFIYGVSSNTYISGFINLEALLKFPGDVIVSTLHEAKQIYLGSSKIFGVSLGAIGCLLLTGVILSLYSASNWKVRATLLILMFGCIISPFALNILAGGARSIPYRSMVGVPYVIWFFSALAIERKNTVITFLITTSLIISSFQIMNAHSNYSAVKQLTLERDKALAAEIYYRITTLIPGNDKLSSYKVDFFGSKPFNNIFPRIVTSTIGGSFFDWDGGNPDRIVTFMKVIGFDNINTIDSGQRRELVGFYDEMPVWPSVDSIKMVDTVFLVKLGERPGLMHQFKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP69</accession>
    <name>A0A1D3RP69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase of IS641</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_221756_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000789">
        <property type="protein sequence ID" value="SCN47491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="127" mass="14091" checksum="1C0440A60F140405" modified="2016-11-30" version="1">MGGIHLVRHDRAGTTIQFYVMMTLALLQLHLKQSIMDKTEINENETYPVKPAESESCRDKKTTQNCNSLHAPHEAGNSRLGEVGFLASLGGTVKKYWKIGVHGLAALRDLLALPFDAKAWHILKISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP83</accession>
    <name>A0A1D3RP83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="15" type="ORF">BAZMOX_47247_1</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="FMJP01000772">
        <property type="protein sequence ID" value="SCN47464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="121"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="13">
        <location>
            <begin position="322"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="123"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN47464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="478" mass="52157" checksum="357BA3CAA70BC6FE" modified="2016-11-30" version="1">MNNSINQVIQERLKNMRKVHFVGVGGTGMSGIAEVLSNLGYEVSGSDIKESSVTQHLSAAGVAVFIGHDTKNVADVDVLVTSTAVDKKNVEVKYAYENRIPVIPRAEMLAELMRFRFGIAVAGTHGKTTTTSLVASILAEADLDPTFVIGGRLNSAGTNAQLGEGQYLVAEADESDASFLHLQPIIGVITNIDQDHMETYEGSFKRLKETFIEFLYHIPFYGLAVLCIDDEGVREILPQLSKPVRTYGVCADADAHIFDVKQQGMCTTFTVKRWDEHKDLTVTLNMPGWHNMLNAVAAITVATELNVNDSAIIESLGSFKGVGRRFELKGEVALAEGAVTLVDDYGHHPREVSATLEALRQAWPGRRSVVVFQPHRYSRTRDLFEDFVNTLSSADVLILLEVYAAGEESITGADGRALTRAIRIRGQVDPVFVEKIEDLASILVGIIQPNDVLLTMGAGNVGHIATELPRQLADLLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP99</accession>
    <name>A0A1D3RP99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_54647_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000786">
        <property type="protein sequence ID" value="SCN47484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920258" evidence="1">
        <location>
            <begin position="21"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="275" mass="31862" checksum="C891ED45C4CCBC19" modified="2016-11-30" version="1">MNKLIIITIALMALSQATFGGEKNALEMAQEVAQQMKTEADKEYAKGVAKRNELHQWPDAADAVKRIQARYDMLELMRHNAQVAYDYYNWHIWCGDTCMDHKRAARHWQGFRDRTQPYIAIAKSHIKTSGTTIGTEVARAKKHLEWAKMEKRWADSMDYIVNNQYRTGEYIDEALITVRAANAEVAWADKSVMNALDVAYRVSDEVLREARRIKYYEADTYLRRQRAVHEAEQAAIEREIELKLEREKAIRGAEQAITDKENAFLQLMKDLLYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB1</accession>
    <name>A0A1D3RPB1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tuf</name>
        <name evidence="10" type="ORF">BAZMOX_151601_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000702">
        <property type="protein sequence ID" value="SCN47379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="406" mass="44137" checksum="4052623CA778433F" modified="2016-11-30" version="1">MAKEKFERNKPHVNVGTIGHVDHGKTTLTAALTKVMAEKMGGEVKAFDQIDNAPEERERGITIATSHVEYESETRHYAHVDCPGHADYVKNMITGAAQMDGAILVCGATDGPMPQTREHILLSRQVGVPYIVVFLNKADLLAEDCGGVGTEEYNEMLELVEMELRELLDLYEFPGDDTPIIVGSALKGLEGDTSELGVPSILKLVAALDEYIPEPVRAIEGAFIMPIEDVFSISGRGTVVTGRIERGVVKVGEEIEIVGIKDTVKTTCTGVEMFRKLLDQGEAGDNVGILLRGTKREDVERGQVLAHVGSIKPHTKFASEIYVLSKDEGGRHTPFFNGYRPQFYFRTTDVTGAVELPEGTEMVMPGDNVSVEVTLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD0</accession>
    <name>A0A1D3RPD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_72545_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SecB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000718">
        <property type="protein sequence ID" value="SCN47399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00821">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003708">
        <property type="entry name" value="SecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035958">
        <property type="entry name" value="SecB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36918">
        <property type="entry name" value="PTHR36918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02556">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01594">
        <property type="entry name" value="SECBCHAPRONE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54611">
        <property type="entry name" value="SSF54611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00809">
        <property type="entry name" value="secB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="16933" checksum="C26C5901312D0746" modified="2016-11-30" version="1">MAEENQAQEKQFSIQKIYTKDVSFESPASPKLFTEKWEPAVDFNLATNATPLEDSMFEVSITVTVTVKTGETVAYLVEATQAGIFSLAGFTDAEMGPMVGSFCPNILFPYVREVVSDLVAKGGFPQLLLAPVNFDALYAQHLQQAQQAEGSKTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD3</accession>
    <name>A0A1D3RPD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00412_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920261" evidence="1">
        <location>
            <begin position="26"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="262" mass="28500" checksum="2A7A240E36A91819" modified="2016-11-30" version="1">MKHQKKILLALSLFLSSTAVNIAYSADLTRQQVEQLLNQASQDKPADLRRKDLKGIDLSNMDLRKADLWGADLRGANLSKSNLSGLVLDLTVMTGINLSGADLTKVSIFGVSMMRSDLSNTNFSDSRVIANLDNSNMTNANLSNVRWGADMKNQPMGLMRVNLNKVNLTNANLQNADLGRASMRFANLTNANLTNASLLSAELTSANFTKANLSKVDFTSAKLREAIFTNAILNGAIFKAVQGQESARDLKNNKTKSAAKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG2</accession>
    <name>A0A1D3RPG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_253185_0</name>
        <name evidence="1" type="ORF">BAZMOX_84593_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000339">
        <property type="protein sequence ID" value="SCN46870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000815">
        <property type="protein sequence ID" value="SCN47544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4650" checksum="4B782F9DEF04DF83" modified="2016-11-30" version="1">MISFKGTHFPKDVILYAVFFYVRYGVSYRDLEEIMEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI8</accession>
    <name>A0A1D3RPI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_241654_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000733">
        <property type="protein sequence ID" value="SCN47418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4106" checksum="082766E0D3257536" modified="2016-11-30" version="1">MLIMLRSIVGGSVASISESEERLVFRHNYPAKAINCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK4</accession>
    <name>A0A1D3RPK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-succinyl-L,L-diaminopimelate aminotransferase alternative</fullName>
            <ecNumber evidence="2">2.6.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00742_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.6.1.17" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000881">
        <property type="protein sequence ID" value="SCN47623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009016">
        <property type="term" value="F:succinyldiaminopimelate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019878">
        <property type="entry name" value="DapC_beta/gammaproteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03538">
        <property type="entry name" value="DapC_gpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="32"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="403" mass="44752" checksum="19F2BD376C1D70AF" modified="2016-11-30" version="1">MNPYLSRLHPYPFEKLAQLKRGITPPADKAHIALSIGEPKHATPAFIKAAILSNIDTLGNYPTTKGLPELRVTIKQWVTQRFDIANEALNAETQILPVNGTREALFAFAQCVVDGSADALVLMPNPFYQIYEGAALLAGAEPYYLNTLEENEYLPDFDKVPEDAWQRCQLLYICSPGNPTGAVIGQATHEKLINLALKYDFIIASDECYSEIYDDEANPPQGLLQSAYAMGHTSFKNCVIFHSLSKRSNAPGLRSGFVAGDAQVLSQFLKYRTYHGSAMPMPTQYASIAGWQDEQHVLENRQFYREKFAATTAILAEVCTVKQSPASFYLWLKTSSDDAEFARQLFAQENVTVLPGSYLSREVDGINPGKNHVRLALVASVDECIEAAQRIKNFINSLNEKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM1</accession>
    <name>A0A1D3RPM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_347379_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000888">
        <property type="protein sequence ID" value="SCN47641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="66" mass="7947" checksum="241E6116D9A07CA6" modified="2016-11-30" version="1">MRRIKGRSASKVFESFPDLKKRYWGRHFWARGYFCVTSGELTEEMIKTYLEHHFEPKGDDNFKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM6</accession>
    <name>A0A1D3RPM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="6">4.2.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_108156_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000838">
        <property type="protein sequence ID" value="SCN47582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="5">
        <location>
            <begin position="61"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="254" mass="27759" checksum="1766C0F06FA16691" modified="2016-11-30" version="1">MTETTKSYNMPDERGHFGPYGGLFIAETLIPAVEELNAAYKKYLVDADFLAELDKDFQHYVGRPSPLYHANRWSRELGGAQIYLKREDLNHTGAHKINNTIGQILLAKRMGKPRIIAETGAGQHGVATATVCARLGLECVVYMGAVDVARQIQNVYRMELLGAKVIAVESGSKTLKDALNEAIRDWVTNVDNTFYIIGTAAGPAPYPAMVRDFQSIIGREAKQQCLAQTGKLPDALVACIGGGSNAIGLFHPFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP7</accession>
    <name>A0A1D3RPP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_15333_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000942">
        <property type="protein sequence ID" value="SCN47715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920279" evidence="1">
        <location>
            <begin position="22"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="152" mass="17028" checksum="F49FB5DCC3CBBAE8" modified="2016-11-30" version="1">MKIVQIIMASCLLVISINSFSGVFSDIKQQAESGNALAQAKIGAMYQLGRNGVDKDAQESARWMRKAADQNMVEAQVFMAALYDRGLGVKQDYNRATEWYEKAAKQKHGTALAILGRNEVAKGSIAFDYKSMRLRASKQIPVEYSKRFLRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR5</accession>
    <name>A0A1D3RPR5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="8">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisS</name>
        <name evidence="10" type="ORF">BAZMOX_08843_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000953">
        <property type="protein sequence ID" value="SCN47735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="421" mass="47674" checksum="D6DEC97A3B3AE97B" modified="2016-11-30" version="1">MANNIQAIRGMHDVLPDQTPRWQFVEQQVRDVLATYGYAEIRLPIVEKTELFKRSIGEVTDIVEKEMYTFDDRNGDSLTLRPEGTAGCLRACLEHGLLHNQVHRLWYYGQMFRHERPQKGRYRQFIQLGVETYGMAGSDIDAELILLSYRLWQRLGILGKVELQLNSLGTIEERTVYREKLVEYFNQQPELLDEDSKRRLLSNPLRILDTKNPAMQALVENAPTLMSYLGAESKAHFKGLTDTLDALGIIYTINQRLVRGLDYYSKTVFEWVTSELGAQGTICAGGRYDGLIEQLGGKPNHAVGFAMGMERILALLETREDLDTIQSIDAYMILVGSAAEKSGLLLAEKLRDSLPNLRLQMNCGAGSFKSQFKKADKSGADYALILGDDEVANNEISIKFLRKDVEQRTVTLAELIELIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR9</accession>
    <name>A0A1D3RPR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00742_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000881">
        <property type="protein sequence ID" value="SCN47622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920281" evidence="2">
        <location>
            <begin position="26"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="192" mass="21190" checksum="E6B2A967AF4EE485" modified="2016-11-30" version="1">MQARFFFLLLTIFSLNLAIPTTLFAHAGVDHGDNCFVDIGGFTLRLGGFQAEDKIGGGKHFCHIFPATGTVIFTFEEDVVAQLNKKMNLKFLAADSYADLIFNNSMAFNQTLVQVSDAAAIQYDFPEAGLYALEVSLESDELEPSTNNTQRFLFLVGFPIIKMLVFTALSFLLMLGFVLLGQLKSGVKPRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU7</accession>
    <name>A0A1D3RPU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_133783_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000889">
        <property type="protein sequence ID" value="SCN47642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="95" mass="10688" checksum="C4A4E62C1B16F8F0" modified="2016-11-30" version="1">MKVTANYANSANYQETQGFEGYYKAETGANSCEFSTLSTQEKVKNSHEFASKKQPKHPSNPHDSYNFAEFAEFAGTQLIDKQKEDEKNKIVTAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW7</accession>
    <name>A0A1D3RPW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional regulators with the CopG/Arc/MetJ DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_334460_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000779">
        <property type="protein sequence ID" value="SCN47477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02606">
        <property type="entry name" value="antidote_CC2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9632" checksum="597980DAB49DF67C" modified="2016-11-30" version="1">MHVSLTNELESRVKAKVESGLYNNASEVIREALRFMDIHEDWIHEVKLARLREQLKVGTDQLDRGEGIAIESKPALDSLFGDIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX5</accession>
    <name>A0A1D3RPX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_16663_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000845">
        <property type="protein sequence ID" value="SCN47589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4661" checksum="25CC2084B3E39625" modified="2016-11-30" version="1">MRVSIVTRLACRHYFFWVVYLLRVTLVFDFGILFDFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ03</accession>
    <name>A0A1D3RQ03_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="10" type="ORF">BAZMOX_24983_2</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000836">
        <property type="protein sequence ID" value="SCN47578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="156" mass="17774" checksum="13B195AA234C34A6" modified="2016-11-30" version="1">MSRRRAAIKRNVLQDPRYGSTTLTKFMNMVMVDGKKSVAEKIVYGALEAIESKGHAEPLEVFTKALENIQPRVEVKSRRVGGATYQVPVEVRPTRRVALAMRWLIDASRKRNEKNMPLKLAGEMMDAVEGRGSASKKREDTHRMAEANKAFSHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ12</accession>
    <name>A0A1D3RQ12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_30273_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001000">
        <property type="protein sequence ID" value="SCN47793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4898" checksum="8B9D630F1094DDC3" modified="2016-11-30" version="1">MMFFFVFSGYGRAYFSCTSAHICTGDGTAMVTSNVLLCFQWLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ18</accession>
    <name>A0A1D3RQ18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03410_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0102 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000969">
        <property type="protein sequence ID" value="SCN47754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="78" mass="8863" checksum="ECC5B55DC01853F5" modified="2016-11-30" version="1">MQQGQVLVGRNYRCKWGELDLLMDEQGVLVIVEVRYRKNDRYGSALESITAAKQARIIAATKHYIVAKKLISQLGLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ23</accession>
    <name>A0A1D3RQ23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">tRNA(Cytosine32)-2-thiocytidine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_01376_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001010">
        <property type="protein sequence ID" value="SCN47803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01850">
        <property type="entry name" value="TtcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012089">
        <property type="entry name" value="tRNA_Cyd_32_2_STrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="6">
        <location>
            <begin position="37"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="288" mass="32708" checksum="B1B5D8257AAF2773" modified="2016-11-30" version="1">MSSTKKEQTEFNKLHKRLRKNVGSAIADFNMIEDGDKVMVCLSGGKDSYTLLDILMYFQKIAPIHFDIIAVNLDQKQPGFPEHVLPKYLQKISVPFHIIEQDTYSIVKRVIPEGQTTCSLCSRLRRGSLYGYAKAEGITKIALGHHRDDILETFFLNIFYAGKLKAMPPKLLSDDGQNIIIRPLAYCKEKDIETYAELKQFPIIPCNLCGSQENLQRQMMKKMLENWDKAFPGRLETIFSSLQSVAPSQLADTQLFDFIGLNLDQRADVSVNSAMMEADSYGLDVLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ57</accession>
    <name>A0A1D3RQ57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_494586_0</name>
        <name evidence="2" type="ORF">BAZMOX_523680_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">BAZMOX</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FMJP01000554">
        <property type="protein sequence ID" value="SCN47151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01001022">
        <property type="protein sequence ID" value="SCN47830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="56" mass="6427" checksum="C818696ED03BAE88" modified="2016-11-30" version="1">MYQRTFNKAQQSIEDGQILSPFLLRSAHQVLLSFGRGIDKNPGQFKIEQNYLSNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ62</accession>
    <name>A0A1D3RQ62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tmk</name>
        <name evidence="5" type="ORF">BAZMOX_246502_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000994">
        <property type="protein sequence ID" value="SCN47786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="12"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="219" mass="24578" checksum="B0B3C5B80A03E6F9" modified="2016-11-30" version="1">MSNLLARKFIVIEGLEGAGKSTAIKYVKKWLEQSLIDQKNLVFTREPGGTIFAEKIRDIIKMDIEGESLQDKAELLLLYAARVQLVENTIKPSLAAGATVIGDRHNYSSLAYQGGGRQIDLALIKDIQRISLGDFKADFTLYLDISPEQGLNRAKKRGSLDRIERQEIAFFERSRAVFKNLVEHDENAVSIDAGGKPKTVELAIYQALDQWRTRLENAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA0</accession>
    <name>A0A1D3RQA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MG(2+) CHELATASE FAMILY PROTEIN / ComM-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_262875_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001094">
        <property type="protein sequence ID" value="SCN47925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="159" mass="16945" checksum="78100A8F306DD8E1" modified="2016-11-30" version="1">MVGLPEAAVKESKDRARGAIINSHFEFPMQRITINLAPADVPKEGGRFDLPIALGILAASGQIPIAELAKYECIGELSLGGELRSVNGVLPVALQAREAQRPLFLPLENSQEAALVQQAELLPAQHLTDICAHLNGFHKLDAAIPAPEATHSDSDAPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD9</accession>
    <name>A0A1D3RQD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_06810_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000897">
        <property type="protein sequence ID" value="SCN47657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="55" mass="6474" checksum="12C4E7CAF37A22E6" modified="2016-11-30" version="1">MGWDAKKKLSQNSDSPKFRFFHPVVITFLSRDLDRNIYALDHRSNPYAALLRAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQF8</accession>
    <name>A0A1D3RQF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-deoxy-8-phosphooctulonate synthase</fullName>
            <ecNumber evidence="6">2.5.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_23253_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="EC" id="2.5.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the KdsA family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.55" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000919">
        <property type="protein sequence ID" value="SCN47677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00357">
        <property type="reaction ID" value="UER00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008676">
        <property type="term" value="F:3-deoxy-8-phosphooctulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006269">
        <property type="entry name" value="KDO8P_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21057">
        <property type="entry name" value="PTHR21057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="7">
        <location>
            <begin position="8"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="81" mass="8582" checksum="2148556DAD32C9C1" modified="2016-11-30" version="1">MQLPGGQGTSSGGQRQHVPVLARAAVAAGISGLFMETHPDPDKALSDGPNSWPLHRMKELLETLVIIDQAVKAQALIENTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQG6</accession>
    <name>A0A1D3RQG6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="2">CKS</shortName>
            <shortName evidence="2">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kdsB</name>
        <name evidence="3" type="ORF">BAZMOX_35365_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001079">
        <property type="protein sequence ID" value="SCN47904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="253" mass="28723" checksum="C3FA83FC60AF0A61" modified="2016-11-30" version="1">MTCAFKVVIPARYDSSRLPGKPLLMIAGKPMVLHVCDRAKEAGAEKIIVATDDFRILEVVNDYGFEAVMTRTTHKSGTERLAEVAEIFQWHEDDIIVNLQGDEPLIPAEYISLAAQSLAMQSTAGVATLAAEIIEFEEIFNPNSVKVVLDKFNYALYFSRAAIPWDRECFKKKQVDSVKSDTYFRHIGMYAYRVSFLQRYIQWDVSAIERIEMLEQLRILWEGEKVLVAKVAKTPEAGVDTPEDLLRVERSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQN4</accession>
    <name>A0A1D3RQN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_485460_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000988">
        <property type="protein sequence ID" value="SCN47777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="2"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="56" mass="6235" checksum="AC44B9A2C2E5E721" modified="2016-11-30" version="1">MDKSGANYAGLANINLLLILAGFATLIDICQIKYLNNIIEQDHRFIKKNNQTNDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQP3</accession>
    <name>A0A1D3RQP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RepA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_146868_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001075">
        <property type="protein sequence ID" value="SCN47899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018777">
        <property type="entry name" value="Replication_initiator_prot_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10134">
        <property type="entry name" value="RPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="343" mass="39574" checksum="17B2A8EC3FCD7C06" modified="2016-11-30" version="1">MTEPLLPIRHPEKNLFICDFGEVIPKSDIASMEHPLFTLSTKPDTAIRKYEHNGNTVTIAPSAYGRATIHDKDILIYCISQLMAGINQGNEPSRKIRFKAHDLLVTTNRGIGGTEYKGLRKAFERLSGTRIGTNIKTNGQEIIEGFGIIDSYKIVIDDPKTKRMVELEITLSEWLYNSVIGEEVLSINHDYFRLRKPIERRIYEIARKHCGKQKRWHIGIENLHKKVGSSGSLKKFKEAISHLVKHNHLPEYNIYYESGNVLFYYRGYQEKPAIQAQQDNNRPFLKPDTIEKAKHVLGRHFDVYAIESEWLQWWEQSGKPELQSPDGAFFNFCKARMEKIQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQU8</accession>
    <name>A0A1D3RQU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_52815_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001080">
        <property type="protein sequence ID" value="SCN47908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4575" checksum="7163415AB7F85A6C" modified="2016-11-30" version="1">MIMALMLAPVGKLARTLVALKEQREEGSVSAESETEVVSEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-11-11" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0K2YZS4</accession>
    <name>A0A0K2YZS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_359617_0</name>
        <name evidence="2" type="ORF">BAZMOX_60641_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000346">
        <property type="protein sequence ID" value="SCN46881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000863">
        <property type="protein sequence ID" value="SCN47608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4798" checksum="521F313B049AE952" modified="2015-11-11" version="1">MMGFKAFHSAQATIAGIETAHMIRKGQLSEENIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL13</accession>
    <name>A0A1D3RL13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-C4_Topoisom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04471_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000015">
        <property type="protein sequence ID" value="SCN46405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003916">
        <property type="term" value="F:DNA topoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-C4_Topoisom" evidence="1">
        <location>
            <begin position="140"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="190" mass="21407" checksum="8D649D5C3B47D02C" modified="2016-11-30" version="1">MNLWERTKSVAKMYTGTFIVVMVLNQLVFFGFCLNPICLIAAMPHVLLITVFIGSWLNKESGWGDEKQAGNVGKIYKEGKGLVDKSLEQAAIDLKKANELASQKTVKEEYYDADYEVIEAKVLEAPAVKKPESEIDYDVCQTCGAKTVLRTARVEKYAGREFYGCSRYPECKGITNIEPKKESDYSDFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL35</accession>
    <name>A0A1D3RL35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_293061_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000026">
        <property type="protein sequence ID" value="SCN46425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4692" checksum="C507485E4D778483" modified="2016-11-30" version="1">MRDSILGVRPVLVFKKRSLSVAFLDSLIRLGIIYAVSVVCQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL53</accession>
    <name>A0A1D3RL53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04471_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000015">
        <property type="protein sequence ID" value="SCN46402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4604" checksum="C9127E75D81A13EE" modified="2016-11-30" version="1">MIAMAQLVLLREGSAPCGSACGVLWGEPERNQLLPDLGFFQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLA2</accession>
    <name>A0A1D3RLA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c, class I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_465758_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000042">
        <property type="protein sequence ID" value="SCN46446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="5"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="105" mass="11130" checksum="2DB2E7A4C3DFFE83" modified="2016-11-30" version="1">MAQAGSVEAGRDAFEACRGCHTSPGTSNVYPTYYVPKVGGQVPAYTVAALKAYQKSERPHRTMMANVYDLSDQTLEDIAAYLATVDGSKRANANAENQGNGAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLD8</accession>
    <name>A0A1D3RLD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AbrB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_04903_4</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000068">
        <property type="protein sequence ID" value="SCN46483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097351">
        <property type="term" value="F:toxin sequestering activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001558">
        <property type="term" value="P:regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031848">
        <property type="entry name" value="PrlF_antitoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15937">
        <property type="entry name" value="PrlF_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01439">
        <property type="entry name" value="lp_hng_hel_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="83" mass="9276" checksum="F3D5FCDF39B63345" modified="2016-11-30" version="1">MSLSTVTTKGQVTIPKDIRESMAIDAGDKIEFIINAQNDVVIKPITKKAIDIFGQLSQYKKDKPLSIEEMNEAITTQCKKEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLF2</accession>
    <name>A0A1D3RLF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_372223_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000011">
        <property type="protein sequence ID" value="SCN46399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="3"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="5023" checksum="03D69CE0B7E44FAA" modified="2016-11-30" version="1">MNEYQTVPELRSGLKRYFEFYNQERLHQSLGYKTPSEVHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLF8</accession>
    <name>A0A1D3RLF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA repair protein RadA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_11721_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000081">
        <property type="protein sequence ID" value="SCN46500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="245" mass="26579" checksum="46393E8AB1BB2423" modified="2016-11-30" version="1">MVGHVTKDQSLAGPMTLSHIVDTQLILASTDDARFRVLRADKNRFGSVGELGFFAMESGGLKEVKNPSAMFLNRTEKPSPGSVVTVLWEGTRPLLVEIQALVTECQYGNPRRLAVGFDQNRLAMLLAILTRHGGIFTASDEIYANVVGGIKVTETSSDLAIIISIVSSLKDTIVPHDCFFFGELGLNGEIRPVANGYARLNDAVKHGFKKAIIPKSNAPKKSMPGIKIYPVSSLVEALEALEEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLG0</accession>
    <name>A0A1D3RLG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Decarboxylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_13546_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000077">
        <property type="protein sequence ID" value="SCN46496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021826">
        <property type="entry name" value="DUF3412"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037153">
        <property type="entry name" value="YgdH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027820">
        <property type="entry name" value="YgdH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11892">
        <property type="entry name" value="DUF3412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14793">
        <property type="entry name" value="DUF4478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4478" evidence="2">
        <location>
            <begin position="9"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3412" evidence="1">
        <location>
            <begin position="336"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="456" mass="50587" checksum="D941743D67889F77" modified="2016-11-30" version="1">MKEHTIDTRISPAGHLAVLSRSEVNKLLDTSQGGLYGLLHNCALAVLNCGSDSDDGKELLERYSDFAIKVIQEERGIKLELTSAPAIAFVDGEMIKGIREHLFAVLRDIVYVSDEINDNPKFDLQSSEGITNAVFHILRNANIIQQSTDPKLVVCWGGHSISRDEYVYTKKVGYELGLRNMDICTGCGPGAMKGPMKGATIGHAKQRISDGRYIGISEPGIIAAESPNPIVNDLVILPDIEKRLEAFVRTGHGIIVFPGGAGTAEEILYLLGILLHPENAEIPFPLIFTGPNTAADYFNQINEFIGNTLGFEAQQRYKIIIDDPARVAREMKLGIYQVHEFRKSKTDAYYFNWGLKIDVEFQQPFLPTHENMAELALHKNQEKHLLAANLRRVFSGIVAGNVKDEGIRAIEQHGHFEISGDKEIITPIDALLTAFISQHRMKLPGKTYVPCYKIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLG9</accession>
    <name>A0A1D3RLG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenazine biosynthesis protein PhzF like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_06966_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000090">
        <property type="protein sequence ID" value="SCN46510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="69" mass="7842" checksum="B227238AE8B6DB72" modified="2016-11-30" version="1">MNYTYYIADVFTNQVFSGAQIAVFPNAEGLNLTQMGLVARELNLSETVFLTHKKGVENHYTMKIFTPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLJ5</accession>
    <name>A0A1D3RLJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_445353_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000096">
        <property type="protein sequence ID" value="SCN46514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="10683" checksum="A1EA244D6DA54B81" modified="2016-11-30" version="1">MDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIIEQDHRFIKKITKPMMGFKAFHSAQATIAGIETAHMIRKGQLSEEYMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP6</accession>
    <name>A0A1D3RLP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_08668_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000180">
        <property type="protein sequence ID" value="SCN46625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920231" evidence="2">
        <location>
            <begin position="25"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="187" mass="20821" checksum="8107EBF8A05FC1ED" modified="2016-11-30" version="1">MKKSIVKSSLLALAGLFFSATLWAHGGAAGTDTDQCKFELEPDHWIHYTAYQPLAYPAEDFCGNLPDIGTMTQLVFDYQDIRFRNMAVEFEVTKEPEGTQIFFMPAKKHKSGSVILKLPNGVPEVGKYLIHITLVKDNGERLDAHMSFVAGKGAVTSSKTMFMYLLFALAGLYVLYLSHAGFKNESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ4</accession>
    <name>A0A1D3RLQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_75130_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000162">
        <property type="protein sequence ID" value="SCN46596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010980">
        <property type="entry name" value="Cyt_c/b562"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47175">
        <property type="entry name" value="SSF47175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="119" mass="13486" checksum="A13BFD454BE29CAD" modified="2016-11-30" version="1">MQAIEQGVTALIPAIARGEWDQIAKIGRHIEQSYLLKQQLTPEQRHSLHKSLPARFIQLDQAFHKSAGMLAHGAEMKNPDIVNFYVYKLSSACVECHTEFATEKFPSLVREQAKAHSHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU4</accession>
    <name>A0A1D3RLU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Relaxase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00432_7</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000065">
        <property type="protein sequence ID" value="SCN46478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040677">
        <property type="entry name" value="LPD7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18821">
        <property type="entry name" value="LPD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LPD7" evidence="2">
        <location>
            <begin position="343"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="749" mass="86145" checksum="8AAED23729A78EF4" modified="2016-11-30" version="1">MLARPTRGKSGLCDYLENGQKKDSIYTRDQKDHVVPIYGDLSINKKCEAFLVKNKSYAHNYTHITLGFSESDMEKIENMSDEERSDFLYNLTEDYIKHHTSGHDLKNEVIAYGEAHFPKVKYENGKKRLGHIHIMIMNYNPVADTTLRTTFRTNDFIDNTLQAWACKKYGLEIPKRERERTVKTEMAISRKELIELLQDVKGFAELRAVLKDNGLEWREEVGKDKYFKVLNKGTNDINLRGKGFEHISEISKDKGMHLNKSRTEGELAKILNDFYERRVKEMDGRRSKKTKEAMQTLHTSVNPSVKVDSIELSYQQKIFKSLYKKVSESDLKGYYIDTSNKNATVFTNKKKSIKVVDRGDKITSDIQNANQEEKVKLMLDIAEAKGWNLATISINGNDAFKKEARRQIVKRLDLSIKTLSLTEAVAIKEQTKRPRSPVAEKKREDQSQKDKGKEGLKDLKENLNAKTVLAYAEKHFKLDVSQYEVTADNKINNKNDKKKPKNVIDFLGREIGMTSKEAITIVKELYGDQPMPIKTAEPVQVSEPIELKQRKEDHEYSKAQRATALLKSSHRENGERGRQTKNDLHKLSSSNMVLSGRKRTTMLLSANERNNVQQEREADNGLLTARARATQTPIKTRREIRGLKMPLYISVTDDKTKVEVEIIRNGKSQKMLVEVANKGWSKVEVNGYAQLATIMKTQKYSSSRFDKNYRNKDNGFCRKHRLIAGFLSHLWVNSDIIPLLFPNVHKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV0</accession>
    <name>A0A1D3RLV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antirestriction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_32210_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000178">
        <property type="protein sequence ID" value="SCN46624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013610">
        <property type="entry name" value="ArdC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08401">
        <property type="entry name" value="ArdcN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ArdcN" evidence="1">
        <location>
            <begin position="8"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="132" mass="15150" checksum="921DF01534E83509" modified="2016-11-30" version="1">MAYSKSKRDLYQEVTDKIIDSLEQGVSPWVCPWDRSGEMTLPVNHSSGDFYRGINVCLLWMEQQLRGFSSSRWMTYKQAAVKGGYVKKGEKGTTVIFYKTGEKETGEFNENGEGIIEKFLCCVLSPFLIWIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV9</accession>
    <name>A0A1D3RLV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_40961_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000201">
        <property type="protein sequence ID" value="SCN46661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="318" mass="35672" checksum="B414A0B7F5236A3D" modified="2016-11-30" version="1">MKKVTGIKSVDFKITALGHGVVNWNGPTTLTGDGGKTVDNHTLPKLRGYTNLTGKEKEGTGYKYKKEATDIDFKKTPLYISQNCIRHHLFRNQAFDIHYAAEKSLQGVLASITGLIRGFVVPSSQCKRTSPLLMEDFVDELGNGNFEQFGQAGERDSSSFFSKTTFGNTKYTSYGSISIEQLQFISLDKKFDRCAMVIKEGQGEEVAQAVQGFIQSLNPDLSPQAVFHHNYVRGGTIFEEGENGILLNNDAIQALIEHSLQMISELSIRQAKAYMYVDEILVDYNDSHKMMRIKHSEGGYIRTTQFRLCCLFLCQVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW5</accession>
    <name>A0A1D3RLW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type III effector HopPmaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00299_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014984">
        <property type="entry name" value="HopJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038604">
        <property type="entry name" value="HopJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08888">
        <property type="entry name" value="HopJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="133" mass="15142" checksum="032693E06DD709A0" modified="2016-11-30" version="1">MRFVPQHILPPLKNKNMPLNTFLTKIKSQQKVSFDDTMAIINQHYQYTPTTFSNGLGDNIVINKAGTNEGSCKIFAFAQLHQLNPAQTLNLFGNFYQDVLNDPEGDSHQNIRNFMQSAWEGIKFNTPNTLKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX1</accession>
    <name>A0A1D3RLX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease V gamma chain</fullName>
            <ecNumber evidence="3">3.1.11.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_49042_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.11.5" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000207">
        <property type="protein sequence ID" value="SCN46671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="225" mass="26295" checksum="61DB8C71B8DAAD9A" modified="2016-11-30" version="1">MFILHSSNKTENLLEHLATIINTVPLDSPFTKEIFLIQSQGMERWLAQQLATKFKTFANFEFLFPGKFFSQMARQIQQQLQSDEFARELMVWRFELILRELDEPVFSPLAQYLNGENTDLKRFQLATHLAQVFDQYQIMRPQMLDTWQQGKLLYATNTEKWQQALWLKLTAQTGTRHRGALWLQTIAQFDQLAEGALNEQLPERISIFGLNTDATFVYGILTRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY1</accession>
    <name>A0A1D3RLY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RecD-like DNA helicase YrrC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_15368_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000212">
        <property type="protein sequence ID" value="SCN46681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01488">
        <property type="entry name" value="RecD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006345">
        <property type="entry name" value="DNA_helicase_RecD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029493">
        <property type="entry name" value="RecD-like_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041451">
        <property type="entry name" value="RecD-like_SH13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14490">
        <property type="entry name" value="HHH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18335">
        <property type="entry name" value="SH3_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="343"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="823" mass="92774" checksum="D8359EDA040E3539" modified="2016-11-30" version="1">MSSITEVLTGIVNRVTYHNTATGWSVLRVQPFHAPEQQETVTVHQTKVFAGATMEFRGAWTIDKKYGRQFKATEAIEKKPATTAAIEKYLGSGLIKGVGPQTAKKIVKHFQENTLDIFEHEIKRLTEVPGIAIKKLEMIEQAWTEHRAIRQVMMFLQGHGISTLFAVRIYKEYGDKAIEMVTEDPYRLSNDFYGIGFFSADKVALSIGLAEDSQQRMMAAIKHVLAASRDQGHCYLTEQQINTGILDLIAMNLGEQLNVYLSLMKQEGQLCTRLIYKESIEATGYYSKTLYFDETTVASILRKMNSSISSDPDRISHWISSYCELKKIALSDEQAEAVKGVVQHRFSVLTGGPGCGKTTTTLVIVRLLEAMKKSVLLAAPTGRAAQRMTEVIGREAKTIHRLLEWKGGKFQMNEESKLKTDFLIVDECSMLDISLTAALLKAVPESCQLLFIGDPDQLPSVGAGNVLMDIISSSVTPCFRLTQVFRQAQESLIIKYAHQINKGETPYIDSPFKNPDAWKNGADCLFIDSDEATQAQLSFIGRVKRHFDWKIDELENLVAEQTTVTPFEFRIEEAIKSAYEVDFVIPDKFKHVNIEQLHHSDAQVDALKSVVKKIHPWSSLHYGLSAVDSVVKLYLEWIPKYHGRESEIQILTPMTRGSLGSANLNKVIQEKANPPHQSKCQLKVGECIFREGDRVIHRRNNYDLNVYNGDIGKILTINNEGLTAVVSFYPDHREVHYQKEDIMELDLAYAITIHKSQGSEFKAVIIPVLTQHFKMLYRNLIYTALTRAKDLAVFVGTRRALSMAIQQQDVSQRQTALKELLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY5</accession>
    <name>A0A1D3RLY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rieske 2Fe-2S family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_10024_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000213">
        <property type="protein sequence ID" value="SCN46682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="5"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="106" mass="11405" checksum="FF986CA0DA852A58" modified="2016-11-30" version="1">MSEWVDVVAESALAIGEHLVVDVDGIDVAVFKLEDGFYALKDVCTHDGAEIGSGAVDGDEIVCPRHGARFCIKTGQVKSAPAYEDIASLEVRVKAGRVEVKDSRWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ3</accession>
    <name>A0A1D3RLZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_449338_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000214">
        <property type="protein sequence ID" value="SCN46686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4039" checksum="A724E1815DAA6A07" modified="2016-11-30" version="1">MFMSLVSITKYAGEIIAGSLSAYNASRIVSSRPTCIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM21</accession>
    <name>A0A1D3RM21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_09258_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000234">
        <property type="protein sequence ID" value="SCN46716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="17458" checksum="743AB70629827423" modified="2016-11-30" version="1">MDFFIVLEGKGSAIKQRMLAGARKHLSPLLFGQLQTYLNTAQLIQGNIYSVLTPGRESNNKLILVQGNEGDKNENHDPLQVARDFVEYSQLGEAVKVLESAIIETPQRSELHADLIELYQSTDDLEGCNKMQLALAKINHPMQIQWDALNSYFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM28</accession>
    <name>A0A1D3RM28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Particulate methane monooxygenase B-subunit</fullName>
            <ecNumber evidence="3">1.14.13.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00686_4</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.14.13.25" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000262">
        <property type="protein sequence ID" value="SCN46755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106317">
        <property type="term" value="F:methane monooxygenase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106318">
        <property type="term" value="F:methane monooxygenase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006833">
        <property type="entry name" value="NH3_CH4_mOase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023303">
        <property type="entry name" value="NH3_CH4_mOase_suB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023141">
        <property type="entry name" value="NH3_CH4_mOase_suB_hlx_hairpin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023301">
        <property type="entry name" value="NH3_CH4_mOase_suB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04744">
        <property type="entry name" value="Monooxygenase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03079">
        <property type="entry name" value="CH4_NH3mon_ox_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920249" evidence="2">
        <location>
            <begin position="33"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="414" mass="45669" checksum="0244C8A72C951C26" modified="2016-11-30" version="1">MKTIKDKVAKLSFVALLMALTSAMFYTPTASAHGEKSQAAFMRMRTIHWFDLDWSKDEVAVNDTMTISGKFHVFAGWPETVDKPEVSFLNIGIPGPVFIRAGSWIGGQLVPRSVSLELGDTYEFKVLLKARRPGDWHVHTMMNVEGGGPIIGPGKWVTITGSMGEFVNPLTTLTGQTIDLEDYALDNVYFWHALWYSIGLAWLIFWIKRPMFIPRHIAVTSGKADTLISATDKKVAIGFAVGTLALLMYGMGSTNEKYPITTPLQAGLMRGIKPIEMPETSVAVKVEDATYRVPGRAMQMTLTITNNGDSAIRLGEFNTASVRFLDADVLEDESGYPDDLLAEEGLTVSDNSPIAPGESRTVEVTASDAAWEVYRLADLIYDPDSRFAGLLFFFDEDGNRQMVMVDAPLIPSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM41</accession>
    <name>A0A1D3RM41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_113370_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000149">
        <property type="protein sequence ID" value="SCN46578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="26"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="350" mass="39320" checksum="C1E4136C4F5929E9" modified="2016-11-30" version="1">MVSKSFPLWKEGCIHKGSKENIMNIIGIDVSKNKLDCALINDSNHAKFKFKVVSNSEDGFIALIDWLSKHIKSTAQEYHFVMEATGVYHERCAEWLFNTGSKVSVVNPAHIKYYGQSLGVRSKNDKKDSVVLARYGLTQKPIAWEPETPEIRILKALASRLDAIEKDILREKNRYEKSSINPCSDSVLDSIKMILAVLNGEKTNLERLIELHINQYEYLQHNYALLLTIPGVEPVVSRYMLIVIGSRTFKSASQCAAYIGLVPIQNESGSSLKGRSRLSKAGNPVIRAKLYMAAISALQHNPDIKIQNQRLLKKGKSKISALCAAMRKLVHICFGVIKHQRPYQVQASLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM65</accession>
    <name>A0A1D3RM65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_185177_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000282">
        <property type="protein sequence ID" value="SCN46781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="2"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="67"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="223" mass="24506" checksum="369C0C8E0E48836B" modified="2016-11-30" version="1">MIISFINQKGGVGKTTIAINVASALAQQGFKTLLIDADKQGSSSTWASLREETPFQVVSLARENMAKDALSLATEYDFTLIDAPPHAEAISRSCIIASDLVVMPIEPSGLSTWASDVTVQQVEQAREYKETLKCGFVVSRKIGKTVIGRQVREMVENTGMRVFDADIENRVAFAESMTMGQTIFEWGADKKAMAEIETLTKELVNYGKEELSERTETEKLSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM91</accession>
    <name>A0A1D3RM91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_507659_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000307">
        <property type="protein sequence ID" value="SCN46815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5313" checksum="A93479BE6AE492F0" modified="2016-11-30" version="1">MILFYAHWETKGGLYQNLSINATGIPQLAYACDRTLLIRRVANRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD9</accession>
    <name>A0A1D3RMD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_481614_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000333">
        <property type="protein sequence ID" value="SCN46865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5534" checksum="253752D7CE46DE83" modified="2016-11-30" version="1">MFIVQVTLLDRLHYLDRKMMGFKAFHSAQATIAGIETVHMIRKGQLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF9</accession>
    <name>A0A1D3RMF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ribosomal protein S12p Asp88 (E. coli) methylthiotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_21399_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="FMJP01000191">
        <property type="protein sequence ID" value="SCN46647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="45"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="7">
        <location>
            <begin position="285"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="350" mass="39400" checksum="31BF8C68095E1ABD" modified="2016-11-30" version="1">MARHPQVLEITGAHALEEVVSAVHKHLPPLHDPYTSLVPPQGIKLTPKHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVHEVMWEAKRLADSGVKELLVVSQDTSAYGLDLKYQAYDWQGKEVRTRFYDLAEALGELGVWVRMHYVYPYPHVDEVIPLMAAGKILPYLDIPFQHANARILKLMKRPAATQNNLERIKAWRDVCPDIILRSTFIVGFPGETEAEFQELLDFLTEAQLDRVGAFAYSPVKGAVANDLPDSVPEEVKQERLARFMAHQAEINSARLQRRVGRIEKVLIDEVVDEGAVARSMADAPEIDGQVFIDGATQLKVGDIVIVEIEEADDYDVWAKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMG0</accession>
    <name>A0A1D3RMG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS2020, hypothetical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_455628_0</name>
        <name evidence="3" type="ORF">BAZMOX_71781_1</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">BAZMOX</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FMJP01000331">
        <property type="protein sequence ID" value="SCN46860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000449">
        <property type="protein sequence ID" value="SCN47025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="6975" checksum="3EAA8E0807AB735D" modified="2016-11-30" version="1">MNNIIEQDHRFIKKITKPMMGFKAFHSAQATIAGIEAAHMIRKGQLSEENIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI3</accession>
    <name>A0A1D3RMI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00671_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000273">
        <property type="protein sequence ID" value="SCN46769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="33"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="251"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="734" mass="82915" checksum="583703EBFC371176" modified="2016-11-30" version="1">MTEEHQRLDKRVQKWLFNQGWPDLREIQKRAIAPILAGDRDVLISASTAAGKTEAFFLPACSAIAEEESGFGILYISPLKALINDQYRRLETLSEMLDMQVTPWHGDSLQSKKKKARNNPSGILLITPESLESLLVREPGWVKQSFTSLKYIVIDEFHAFIGTERGQQLLSLLTRLEHITNRISNPIPRVALSATLGELEKVPLSLRPNKSLPCETITSSKHQSTIKVQVKGYLEPVDIMADDTRTSAEQQICQEIYRLCRGDSHLVFANSRSRTESIAAQLSDLCDQQVVPNEFFPHHGSLAKELREDLEARLQKETLPTTAICTMTLELGIDIGKVSSVIQVTAPHSVSSLRQRLGRSGRRNSPSILRMLIAENELSDKSNIVDGLRLELVQSLAMIRLLIVRNWFEPADTEQMHLSTFLHQILAVIAQWGSARTDQLYSLLCEQGSFKEITIEHFKQLLSHMGTVQLIQQLNSGELVLGIEGERLTNSYTFYAVFKTPEEFRIIAGSKTLGRLPVDSLILKDQHIIFGGRRWKVTDIDDEKKVIYVTSTKGGKPPKFNGSGMSIHDRVRQEMLSIYRTGDYRIEVGNQKIDFVDNTGRQLFQEGAYLFKEACIEEQPVYQSGKHCYIFSWMGDKVVNTLTVLLIRSGFVCSNFAGVIEVQNTNVDNIKNCLIDIAKDELPDETELAGILSIQQKLNEKYDEYLPEDLLTEGYGRKAFNSRAAKQWILTLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ8</accession>
    <name>A0A1D3RMJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02486_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000370">
        <property type="protein sequence ID" value="SCN46921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4785" checksum="520B607B10975F52" modified="2016-11-30" version="1">MMGFKAFHSAQATIAGIEAAHMIRKGQLSEKNMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML0</accession>
    <name>A0A1D3RML0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Segregation and condensation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_03068_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000379">
        <property type="protein sequence ID" value="SCN46931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019345">
        <property type="entry name" value="ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="193" mass="21655" checksum="BF3A0098CE447EC1" modified="2016-11-30" version="1">MTEKSAEPAQRVNTTVKRIVEALLFAAEQPMSVAQLQAVFPELERPERVIIEAAVEALCDDYRNQAIGLHKVASGYRFQVKTDMADWVARLFSEKPPKYSRALLETIAIIAYQQPVTRGDIEEIRGVSVSSNMIHTLLDREWIKVIAHKEAPGRPALYATTAQFLDYFNLDSLAAMPPLQELQALALEGEMEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM9</accession>
    <name>A0A1D3RMM9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Na(+)-translocating NADH-quinone reductase subunit B</fullName>
            <shortName evidence="13">Na(+)-NQR subunit B</shortName>
            <shortName evidence="13">Na(+)-translocating NQR subunit B</shortName>
            <ecNumber evidence="13">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">NQR complex subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">NQR-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nqrB</name>
        <name evidence="15" type="ORF">BAZMOX_02303_0</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the NqrB/RnfD family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="13"/>
    <dbReference type="EMBL" id="FMJP01000354">
        <property type="protein sequence ID" value="SCN46896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00426">
        <property type="entry name" value="NqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010966">
        <property type="entry name" value="NqrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578">
        <property type="entry name" value="PTHR30578"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016055">
        <property type="entry name" value="NADH-UbQ_OxRdtase_B_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01937">
        <property type="entry name" value="nqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 13 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 13 14" id="KW-0288">FMN</keyword>
    <keyword evidence="11 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 13 14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 13" id="KW-0813">Transport</keyword>
    <keyword evidence="13" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="13 14">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR016055-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN46896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="400" mass="43667" checksum="932F011F5E5A8D9E" modified="2016-11-30" version="1">MSARDFLDSIEPIFTKGGKLEKYYGLYEMVDTFIYTPSDVTHGTTHVRDGNDLKRTMTFVVIATFFCILMAMYNSGYQANLAMEAMGLEEAAGWRSIPMMMFGYNPMNPLSNFVHGALFFLPIYIVTLAVGGVWEVLFATVRGHEVNEGFLVSSMLYTLILPPDMPLWQVALGISFGIVIGKEVFGGTGKNFLNPALTGRAFLFFAYPAAISGDSVWVGVDGFTAATPLGLAATGGLDAVHAAGYSWFQTFMGFMPGSIGETSTLAILIGAAFLLYTKIASYRIMGGVLVGMIATSVMFNIIGSDTNPMFSMPFYWHLTLGGFAFGMVYMATDPVSAAMTNKGRWIYGAVIGVMVVLVRVVNPAFPEGMMLSILFANMFAPVIDYFVVQANIKRRMKRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN9</accession>
    <name>A0A1D3RMN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin biosynthesis protein MoeA / Periplasmic molybdate-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_28918_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000410">
        <property type="protein sequence ID" value="SCN46965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12727">
        <property type="entry name" value="PBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_domain" evidence="1">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="115" mass="12413" checksum="0D21803D9A2D1EB2" modified="2016-11-30" version="1">MLCQAGIDSALINGYANEEFTHSAVAAIVASGAADCGFGLQAAAAQFNLTFIPLNWESYWFILPKAKREHILFRSFIDLLASDVFKQSVAGVLGYDVSRSGSVVEPSHDLSILLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP3</accession>
    <name>A0A1D3RMP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-binding protein Uup</fullName>
            <ecNumber evidence="5">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">uup</name>
        <name evidence="8" type="ORF">BAZMOX_33930_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Associates with ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000371">
        <property type="protein sequence ID" value="SCN46924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00848">
        <property type="entry name" value="Uup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043686">
        <property type="entry name" value="Uup"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="319"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="351"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="628" mass="70784" checksum="1D68D362D7F27B36" modified="2016-11-30" version="1">MALLRLKKVSIAFGTHALLNKADFQLEEGERVGLLGRNGEGKSTLMKVVMKQIQADEGEIWYKPELRIAVLEQMPHLPDEETIYDVVAGGLGEVGRWIKRYHELTVHMTGMTDAVMTEMGNLQHKLDVHNGWQIQQRVENILTRLNLPAETKIAGLSGGWKRRVSLAKALVIEPEVLLLDEPTNHLDLESILWLEEQLLNFKGAILFVTHDRSFLQKLATRIIDLDRGNLVSWPGDYADYLVKKAAALEEEATQNALFDKKLAEEEVWIRQGVKARRTRNEGRVRALMALRKERSQRRNLQGTTKIAMDRGDISGKKVVEFIDVTFNYPEKPIVNHFSSVIQRGDKIGLIGPNGVGKTTFLKLLLKEIEPNSGVVEQGTKLQVAYFDQLREMLDPEMSVSDAIAGGNDHVIINGEPRHVISYLSDFLFAPARARSPIKTLSGGEKNRLLLAKLFTKPANLIIMDEPTNDLDMETLELLEERLVEYEGTLLIVSHDRVFLDNVVTSVIVFEGQGIVNEYVGGYSDWLEYSKKQAKLVAKPSKKKAPQAAVSSPKKQKLSFTEKKELEELPAQIDKLEAKQGAVNAKIADPKFYQQEQDVITVVLSELAQIEKDLAQAYQRWDELEAIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ0</accession>
    <name>A0A1D3RMQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_03539_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000250">
        <property type="protein sequence ID" value="SCN46737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35011">
        <property type="entry name" value="PTHR35011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920257" evidence="8">
        <location>
            <begin position="22"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="187" mass="20907" checksum="545DFABDF634A27D" modified="2016-11-30" version="1">MLHFAILSFIMASSFSFLQQAAQAIDALNEFVGRLVSWLTLAMVLTTFIIVVLRYLFDLSWVPLQESIIYMHSLVFMLGAAYTLKHDGHVRVDIVYHRCTRVVKAWIDFFGTLLLLLPVAGFILWSSWEYVADSWAITEGSRNSGGLPLVYLLKSCLLLMSGLLILQGISLLISKLNIIITAGAKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ6</accession>
    <name>A0A1D3RMQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anthranilate synthase, aminase component</fullName>
            <ecNumber evidence="2">4.1.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_114381_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.1.3.27" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000405">
        <property type="protein sequence ID" value="SCN46960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="254" mass="27974" checksum="6560C45065DE98EE" modified="2016-11-30" version="1">MQVVLSQRLSIPFSAEPLDLYRALRCLNPSPYMYYLNLDDFHIVGSSPEILVRLEDKTVTVRPIAGTRPRGKNHTEDIALEKELLADPKELAEHLMLIDLGRNDAGRVSQIGSVELTDKMIIERYSHVMHIVSNVTGKLEEGKDAFDVLKATFPAGTVSGAPKIRAMEIIDELEPVKRGVYSGAVGYISWSGNLDTAIAIRTAVIKDKTLHIQAGAGIVYDSVPRNEWDETMNKGRAIFRAVTMAEAGLGGDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ7</accession>
    <name>A0A1D3RMQ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydroorotate oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_255974_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000375">
        <property type="protein sequence ID" value="SCN46926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="6">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="226" mass="24678" checksum="74C6F9CD7DC8543A" modified="2016-11-30" version="1">MGFNNQGVDYLLKQVERSQYQGILGINIGKNFDTPINQATEDYLISLRKAYLAASYITINISSPNTKNLRQLQQGDEIKKLLSALKEEQVKLQTQHNKYTPLVVKIAPDLTDEEIQHIAKLLIEFSIDGVIATNTTIDRSAVQGHPLVDEAGGLSGAPVKQKSTYVVSRLADELQGQLPIIAAGGILCYADAQEKLDAGASLVQIYSGLIYTGPQLVHDIMQGLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV7</accession>
    <name>A0A1D3RMV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00523_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="174" mass="18631" checksum="F0497B8F80BAC2A1" modified="2016-11-30" version="1">MSKVIAILNQKGGAGKTTLSTNIARALQSGGKNVLLVDSDPQGSARDWNAASDASFVPVVGLDRPTLSKDILSVKDDKDFVVVDGAPQIAEMAVSAIKCSDVILIPVQPSPYDIWACEDMVDIIKARQEVTNGLPKAAFIISRVIKNGTVARIGESEERLVFRHNYPAKAINCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX6</accession>
    <name>A0A1D3RMX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-damage-inducible protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_38472_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000448">
        <property type="protein sequence ID" value="SCN47023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9908" checksum="F9B76CA0964610ED" modified="2016-11-30" version="1">MPWVVALPLISFISFLMDGVFIGAALPKQMRDTILWSLFIIFLPTWYFSQHLGNHGLWLALTLFMLARSLIMLGIYLYYKNKLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX9</accession>
    <name>A0A1D3RMX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_16778_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000435">
        <property type="protein sequence ID" value="SCN47004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="63" mass="6861" checksum="4928BE48538331F3" modified="2016-11-30" version="1">MDFNSFALPTSFFAWSTPITTSYILIIAAEIGDKSQLVCRRAILPHEILGLLSPIFXXIGAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN06</accession>
    <name>A0A1D3RN06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04389_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000477">
        <property type="protein sequence ID" value="SCN47053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="160" mass="18642" checksum="BB6E2536AAAA5142" modified="2016-11-30" version="1">MKWSKWLEKWGMTSLKIKTPFLDMEWKPQDEDKNAAWELYIELLTRITTQPLDDAHGDEETALKSVYSIFPITREVIKGNGRHCIEFTKIAIVVLNQVIRPFTAKWHKLSVQGEFSNPESCQEFREELAELQAVLNIYTKMLGDMAGIEDDLSELEYEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN11</accession>
    <name>A0A1D3RN11_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_32792_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000484">
        <property type="protein sequence ID" value="SCN47070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041423">
        <property type="entry name" value="GyrB_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18053">
        <property type="entry name" value="GyrB_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Toprim" evidence="5">
        <location>
            <begin position="296"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="679" mass="76940" checksum="8E423D398D05ECE7" modified="2016-11-30" version="1">MVNALSERLDLEIYKGGYVYRQTYKHGEPVAPLEKMEATTKQGTQVTFLPSRDTFGDVEFHYEILVKRLRELSFLNSGVRIHVKDVRSGKEDVFEFEGGIKAFVTHLNKNKIPLFPEVFHFTIEKEGVTVEVAMQWNDSYQENIFCYTNNIPQRDGGSHLAGFRGGLTRTINQYIEANGLAKKEKVGTTGDDAREGLTAVLSVKVPDPKFSSQTKDKLVSSEVKPLVESAMNEKLNDFLQETPGVAKAIVNKIIEAARARDAARKARELTRRKTTLDIAGLPGKLADCQEKDPALSEIFIVEGDSAGGSAKQGRDRRTQAILPLKGKILNVERARFDRMISSEEVGTLITALGCGIGKDEYDPEKLRYHRIIIMTDADVDGSHIRTLLLTFFYRQMPELIDRGHIYIAQPPLYKVKKGKQERYVKDDEELNAYLIQLALEKTQLISNPETPAIKGLGLETLANELLAVESIISRMGRRYDTDFLQMLTHVSPLTKEAQKGLEQLTEWFSALEQRLNAAAEATYKLELAYRNEQDYTLTIHKKTHGVEKIVILEAIFFNSNDYRKIATYTENTLDLFSDESYMQMGERKQAVRNFKDAFEWMMREIKKGQHIQRYKGLGEMNPEQLFETTLDVNARVLLQVTVADAIAADEVFTTLMGDVVEPRRDFIVKNALEVSNLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN34</accession>
    <name>A0A1D3RN34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_182985_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000511">
        <property type="protein sequence ID" value="SCN47101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="120" mass="13626" checksum="8CC2A63D742A8FB1" modified="2016-11-30" version="1">MSTKRKSHSARFKARVALEAYKGDKTAAELISAHKISSGQISTWKKCLVAGAVQLFESGRAKAVDEETLTSPLYEEIGRLKVELDWLKKKLTKPIELKRQWIEPEHEAISIRRQCELFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN37</accession>
    <name>A0A1D3RN37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_182985_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000511">
        <property type="protein sequence ID" value="SCN47100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="7320" checksum="B0908F3F6325213A" modified="2016-11-30" version="1">MDRFRIQALDKLLRQSDLSNENKIAAKNMLLKKARIFQKGALKRGKTESVDYYQALIERYET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN57</accession>
    <name>A0A1D3RN57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I restriction-modification system, DNA-methyltransferase subunit M</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_12464_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000493">
        <property type="protein sequence ID" value="SCN47084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="106" mass="12089" checksum="18B6029E34526ED5" modified="2016-11-30" version="1">MNKKGKVLIINAVKEVRQDKNIAFLEPQHIERIYQAYKAFQDQSGFCKVVSIDEVLNHNASLNMALYVSNVNNQEAKVSLDEALVNWTQSSTELKKSMEDLFKVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN69</accession>
    <name>A0A1D3RN69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_20759_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000529">
        <property type="protein sequence ID" value="SCN47122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="93" mass="10969" checksum="7C1008335F2DB003" modified="2016-11-30" version="1">MTWIISDLMNQQEKHGVNFDFKHAMNAISKQLRSEKYTRPYSHRHKETKRLPGFNDKTYSEIKELVAQGLISDVLSKYSAETLKLHHFDYLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB0</accession>
    <name>A0A1D3RNB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugative transfer protein TrbB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01638_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000388">
        <property type="protein sequence ID" value="SCN46947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014149">
        <property type="entry name" value="Conjug-transfer_TrbB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02782">
        <property type="entry name" value="TrbB_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="317" mass="34975" checksum="3E5627849D27BFE9" modified="2016-11-30" version="1">MKDISDEVVRRKQTQLTTALDPVLHLLNDADVVEVMINPDTRVWVERIGEPPEQTDIQITTAEIERAIRLVASIMQTTISTDNPSVAGTLPQWNARIQASMPPMVDSPALCIRLPAKKVFNLNDYVAKGILTVSQSQILHNAVMDRKNILLGGGTGSGKTTLANALLDVISVTGDRVIIIEDNRELQCNALNKVHFYTDANVSLQRALFDSLRWRPDRIIIGEVRDKAALDLLKAWNTGHPGGVATIHADSTREMLTRMCQLIEENNMVAPKAFVAQTIDLCVHIKRDKNSPAGRCLSGISEVTGYKNGEWLISPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND4</accession>
    <name>A0A1D3RND4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6430 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_82608_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000562">
        <property type="protein sequence ID" value="SCN47164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045535">
        <property type="entry name" value="DUF6430"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20016">
        <property type="entry name" value="DUF6430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6430" evidence="1">
        <location>
            <begin position="32"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="82" mass="9353" checksum="E7DDDFE574BBB02A" modified="2016-11-30" version="1">MVFFIPVLAYTLYATRSKRKIELSLSDKVKAKIFFGDLFKSNGIIVIPFNECFDTIVDDKIISSKTLHGKFIQSFLVAMKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND9</accession>
    <name>A0A1D3RND9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02905_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000594">
        <property type="protein sequence ID" value="SCN47225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="3858" checksum="49E2870708C19F7C" modified="2016-11-30" version="1">MKKVLSLLAISLMLIGGTGCMDNPDGSKQKVSSSISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF0</accession>
    <name>A0A1D3RNF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methionyl-tRNA synthetase</fullName>
            <ecNumber evidence="5">6.1.1.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_11998_4</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.1.1.10" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000489">
        <property type="protein sequence ID" value="SCN47079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02800">
        <property type="entry name" value="tRNA_bind_EcMetRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008231">
        <property type="entry name" value="CsaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004495">
        <property type="entry name" value="Met-tRNA-synth_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF37">
        <property type="entry name" value="PTHR11586:SF37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00399">
        <property type="entry name" value="metG_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="42"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="143" mass="15442" checksum="01F77136D2D3743B" modified="2016-11-30" version="1">MTRVEAPKIAAIIEDFKENLEKTAVAPAKIFEPIADEIEFDDFAKIDLRIAKIVKAEHVKGADKLLQLTVDIGDESLNIFAGIKSAYKPEDLAGKLTVVVANLKPRKMKFGMSEGMVLAAGPGGADLWVLHPDDGAIAGMRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF2</accession>
    <name>A0A1D3RNF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04316_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000451">
        <property type="protein sequence ID" value="SCN47028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4636" checksum="59EB4AC959B3C161" modified="2016-11-30" version="1">MRADAMLYIVHIAWYFLHGNVLNKISDWHPRFFFLEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF8</accession>
    <name>A0A1D3RNF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bifunctional uridylyltransferase/uridylyl-removing enzyme</fullName>
            <shortName evidence="1">UTase/UR</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Bifunctional [protein-PII] modification enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Bifunctional nitrogen sensor protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="1">[Protein-PII] uridylyltransferase</fullName>
                <shortName evidence="1">PII uridylyltransferase</shortName>
                <shortName evidence="1">UTase</shortName>
                <ecNumber evidence="1">2.7.7.59</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">[Protein-PII]-UMP uridylyl-removing enzyme</fullName>
                <shortName evidence="1">UR</shortName>
                <ecNumber evidence="1">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">glnD</name>
        <name evidence="3" type="ORF">BAZMOX_01117_4</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13673"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
            <dbReference type="EC" id="2.7.7.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:48600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GlnD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.59" evidence="1"/>
    <dbReference type="EC" id="3.1.4.-" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000457">
        <property type="protein sequence ID" value="SCN47038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00277">
        <property type="entry name" value="PII_uridylyl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010043">
        <property type="entry name" value="UTase/UR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47320">
        <property type="entry name" value="PTHR47320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="264"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uridylyltransferase" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="335" mass="38212" checksum="7F06163FE0903DD2" modified="2016-11-30" version="1">MSMTAQRKDISDPEVIHEFATRVGKIEYLNYLYLLTVADIRATNPELWTSWKDSLLKELYSATANALRRGLENPVLQLDTIRETQSEAHKELLAKGLSAKSIKKAWSHISPDYFLRYYADEAIWHTIAINATSEEDLPLILLRPQNQRGSAEIFIYAQQKQEGFIFSRCTTALDNLGLTILDARIISTQNELYTLNSFQVLEQSGEPISDLRRELHICSTVKQQLCDPPNTQQKNLHIHSRQATHFPIRTQARFYQDPQNTYNILELTTTDHPGLLAKVAHFFRTHQLNLISAKITTIGSRAEDIFSLNTQSKQLLSGEQMQSLAKDLTLLLKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH6</accession>
    <name>A0A1D3RNH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02905_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000594">
        <property type="protein sequence ID" value="SCN47223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="142" mass="15773" checksum="BC84D3C1F9BEACD4" modified="2016-11-30" version="1">MFGGLLSILIAIWVYRTAVQAKTGKVLFWTAGAAITFFVVQLLFYEFNIIIIDTFDGSNIGGDYDRDFTDIGDRKDGGGLQDGFFGSVLGILFEILPLFMAWLSVALIRTKFMLKESINYANLVSGIKDTFIGIKNSFKTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ0</accession>
    <name>A0A1D3RNJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I restriction-modification system, DNA-methyltransferase subunit M</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_224185_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000601">
        <property type="protein sequence ID" value="SCN47233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004546">
        <property type="entry name" value="Restrct_endonuc_T1M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00497">
        <property type="entry name" value="hsdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="284" mass="32149" checksum="C32C6A573383DDFA" modified="2016-11-30" version="1">MQAKKHFDAHIIEEGFWGQEINHTTYNLARMNMFLHNINYDKFNIMLGNTLIEPHFNDDKPFDAIVSNPPYSVKWMGSDDPTLINDERFAPAGVLAPKSKADFAFVLHALNYLSSKGRAAIVCFPGIFYRGGAEKKIRQYLVDNNYVETVISLAPNLFFGTSIAVNILVLSKHKTDTKTQFIDASQFFKKDTNNNRLTDKHIEQIMALFDRKDDVAYLAQCVEHQSITDNDYNLSVSAYVEAEDTREVIDITQLNTELKTTVAKIDQLRSDIDAIVAEIEGDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK2</accession>
    <name>A0A1D3RNK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_80513_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000617">
        <property type="protein sequence ID" value="SCN47252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5497" checksum="842CBAC1B67B7FC2" modified="2016-11-30" version="1">MKSKKNYLSLGVKTFYLEKQVKDSKAYILFHGVFASIDEAKNENAKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK4</accession>
    <name>A0A1D3RNK4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_48137_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000499">
        <property type="protein sequence ID" value="SCN47088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019879">
        <property type="entry name" value="Ammonium_transptr_marine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03644">
        <property type="entry name" value="marine_trans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="16"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="416" mass="43991" checksum="7BE212B06091EE29" modified="2016-11-30" version="1">MDKLTELSYALDTFYFLISGALVMWMAAGFAMLEAGLVRSKNTAEILTKNVALFAIACVMYQLCGYNIMYPAEAVNSIWPGISFLLGEDHTATDVLASNGETYYSVMADFFFQVVFVATAMSIVSGAVAERMKLWAFLVFSVVMTGFIYPIQGFWKWGGGFLDQMGFLDFAGSGVVHLCGATAALAAVLLLGARKGKYGSNGEIHPIPGCNMPLATLGMFILWMGWFGFNGGSELKISDIGEANAVAMVFVNTNAAAAAGVISALLTAHLLFGKADLSMTLNGALAGLVAITAEPLTPTPLLASVIGAIAGVIVVFSVIGLDKMKIDDPVGAISVHGVVGIWGLLAVCISNPEATLVAQLAGIGSIFGFVFVASFATWYVIKIVMGIRVTEEEEYQGVDYSECGMEAYPEFTGTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK5</accession>
    <name>A0A1D3RNK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ser/Thr protein phosphatase family protein, UDP-2,3-diacylglucosamine hydrolase homolog</fullName>
            <ecNumber evidence="1">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_30642_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000622">
        <property type="protein sequence ID" value="SCN47261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="81" mass="9069" checksum="D2FB0AA0A338EB11" modified="2016-11-30" version="1">MKKVIVSTLKDKHLDGVICGHIHHAEIKNMDNFIYINTGDFVESCSAVVEHNDGALELIYWTATEPELKVNETINSNTQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM0</accession>
    <name>A0A1D3RNM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_00619_4</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000609">
        <property type="protein sequence ID" value="SCN47244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="157" mass="18032" checksum="5799D817E3163D61" modified="2016-11-30" version="1">MMQFILNTAEETEAFGAKLFQILPEKCLVFLLGDLGAGKTTLVRGFMRAAGHIGAVKSPTYNIVEEYKIDKRLFFHFDLYRLVDPEELEWIGIADYLQETATCFIEWPEKGQGFLSEPDVILSLTTSDNMRKLLVERMPEHIMDKFLIEKQTHTAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM3</accession>
    <name>A0A1D3RNM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">COG2078: Uncharacterized ACR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_81706_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000607">
        <property type="protein sequence ID" value="SCN47236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027623">
        <property type="entry name" value="AmmeMemoSam_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="PTHR13016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="SSF143447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04335">
        <property type="entry name" value="AmmeMemoSam_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00296">
        <property type="entry name" value="TIGR00296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="184" mass="20969" checksum="4E0126FB161589BB" modified="2016-11-30" version="1">MTKTQQLQLLQTAKDSIAYGLRHGQALPVNSGDYDPELQEIRASFVTLEIHHQLRGCIGMLEAVRPLIVDIAENAFAAAFRDYRFPPVTAAEYAQLEIHLSILTKPELIKFDSEEDLLRQIRPNIDGLILQEGAQRGTFLPSVWESLPEPHDFLCHLKQKAGFDPDYWSDSVKVYRYKCDIISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM6</accession>
    <name>A0A1D3RNM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01797_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000517">
        <property type="protein sequence ID" value="SCN47108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4663" checksum="F388D9C14B4448A1" modified="2016-11-30" version="1">MPTSVMKKKTVARYLTKAFNIRLFTISYVEKAPEINVFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ1</accession>
    <name>A0A1D3RNQ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_00271_4</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000628">
        <property type="protein sequence ID" value="SCN47266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016476">
        <property type="entry name" value="SH3_dom_pro"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04211">
        <property type="entry name" value="SH3_and_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920252" description="SH3b domain-containing protein" evidence="8">
        <location>
            <begin position="19"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="9">
        <location>
            <begin position="18"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="90"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="222" mass="25216" checksum="992DACEDA81F7EBB" modified="2016-11-30" version="1">MKYIVCFILLFSSHIALAKSVYVTDSMKFTLRSGESSSHKIIKMLPSGTRLTLLGANKETGYSQVKTSSGVVGYLPTRFTLNKPISKWFLAKANKELEVLQAENKQLKATLKELKQNNSGALSSNAELTKERDQLSTELSDLRQTASNAIQLKRQNVELQERVVHVERELQQIKREKQALEDSTSQDWFLYGGILSFLGIFFGLLIPKISWQRKHSSNWDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR1</accession>
    <name>A0A1D3RNR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_174777_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000657">
        <property type="protein sequence ID" value="SCN47312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="36"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="84" mass="9971" checksum="EA11B029CFC7177F" modified="2016-11-30" version="1">MEERGVNVDHATLNRWVIRYAPTIDAKAQSQKRNTNRSWRMDETYIKVKGKWVYLYRAVDSHGDTLDFMLSERRDEDAATAFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU3</accession>
    <name>A0A1D3RNU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AbrB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_372342_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000659">
        <property type="protein sequence ID" value="SCN47314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01439">
        <property type="entry name" value="lp_hng_hel_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="74" mass="8371" checksum="2538A08DD2DF6769" modified="2016-11-30" version="1">MLITSKGQITIPKAFREALGLLPHTDVEFERIGEELRIRKAKQSIRGKKLLKVMTGKSDISMSTDEIMQLTRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU7</accession>
    <name>A0A1D3RNU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00412_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="242" mass="25954" checksum="CF8F7250CC2C66A4" modified="2016-11-30" version="1">MPLTKQTILITGAGGGLGSTAALALAQQGATIILLDKSIPKLEKVYDAIIATNAPTPIIYPFDLAGASEVQYHELAATIENKYGQLDGVLHSAAELNAFTPLSIHDTFAWGHTINVNLNAPFLLTQVLLPLLQKAEHASIVFTGDSFTREPKAYLGAYGVSKIALDGFAKILAEELGDAGKIRVNTLIPGPVDSPLRKKSFPAEDKHKLPTMTEIMPAYLYLFSHKSIGTTGQTIDARTFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW1</accession>
    <name>A0A1D3RNW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_15154_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000694">
        <property type="protein sequence ID" value="SCN47371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="57" mass="6535" checksum="CF3F60778108DD1A" modified="2016-11-30" version="1">MAVEKELSAGAILSSKRKIEAKICPICQEEFEAIKKAVFCSNKCRQKDKYERNKLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX2</accession>
    <name>A0A1D3RNX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_15154_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000694">
        <property type="protein sequence ID" value="SCN47373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="3796" checksum="C83C470C2FCB302E" modified="2016-11-30" version="1">MGIPAQASGKNLTRLVNAFGAPIRPRHIAPTQQGVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY4</accession>
    <name>A0A1D3RNY4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ORF">BAZMOX_10545_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000565">
        <property type="protein sequence ID" value="SCN47167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="64" mass="7476" checksum="DE3AD08D40EC7E41" modified="2016-11-30" version="1">MKVSELRQKTVTELNSTLVELGREQFNLRMQKNTGQLSKFDQVKKVRRNIARVKTVVNEMARQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY6</accession>
    <name>A0A1D3RNY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type I restriction-modification system, specificity subunit S</fullName>
            <ecNumber evidence="5">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_239060_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000615">
        <property type="protein sequence ID" value="SCN47249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="44"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="200" mass="22876" checksum="4F5D8C2F5B534937" modified="2016-11-30" version="1">MPMGQEEIGRFIRGSGLQKKDFTDMGVGCIHYGQIYTHYGTYADKTKTFVSEDFAKNSRKAKPGDLIIATTSENDEDVCKAVAWIGNEDVAVSSDACFYRHTLNPKYVAYFFQTERFQKQKRPYISGTKVRRVNADNLAKILIPVPSPEEQVRIVAILDRFDTLTHSISEGLPREIELRQKQYEYYRDLLLSFPKAESDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP06</accession>
    <name>A0A1D3RP06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_41924_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000698">
        <property type="protein sequence ID" value="SCN47376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="291"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="468" mass="53073" checksum="1F53D4FACCD29B81" modified="2016-11-30" version="1">MRTALNHYRDMGFQIALDDLGAGYSSLRVWTELMPDYVKIDRHFIENIDQDSVKLNFVRSIQSMATASNCQVIAEGIETEAEYLTIEALGITFGQGYYFARPCAQPETEITPNLFSNSKVNQANPISKHSKLIEEIIKTTPPTKPETTVKSVLNLFQKETQLEFLPIVKDGFCSGIVYRDQFLIKLFSSQFGIELHGKQAISLFLISPVQSFDKDTAIEQVSQKLTHHLRNDHTFIIMHKGNYLGTGTVIDLLEEITKQQVKNAQHANPLTLLPGITPINEKINFFLHEKQPFAIAYFDLDHFKPFNDHYGYNAGDEAIKLVSRLIQENMDSEMDFIGHIGGDDFIVIARHHHWQEKCQAILKAFEQQAPQYYTEKDRTNKGIHGHDRQGKACFFPLLSLSIGIVAPEAASRCSSHIEIADIASEAKHQAKLLPGNSYFINRRMPESVKPEAKVHTFSTQEKHLQLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP12</accession>
    <name>A0A1D3RP12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_09834_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000773">
        <property type="protein sequence ID" value="SCN47465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="93" mass="10580" checksum="093A5782809A9C5B" modified="2016-11-30" version="1">MPPSRTAIAAHFGLANFPVAYCGLKIITSLALRFPDFQRGGKNGKARAAIPHSPTGACHYWKWLFLILSYRNNSQFLRGEMDVYCYTTSYFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP19</accession>
    <name>A0A1D3RP19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_71251_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000756">
        <property type="protein sequence ID" value="SCN47440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011518">
        <property type="entry name" value="Transposase_36"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07592">
        <property type="entry name" value="DDE_Tnp_ISAZ013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="181" mass="20674" checksum="A17CAF2D03708168" modified="2016-11-30" version="1">MFSSCLLYTYVLSQFNQCVAIRYFQRLCTYYTNSGWMNLTRANISDLLAKKGFNVSRNIVRKLLKKNGYVKRKPLKNKTGGGHVDRNAQFERIAELKEKHHADGNPVISVDTKKKEQIGNLSREGKIYTTETVEVFDHDFPSLAEGVAVPHTVYDQTRNEAYVTIGTSRDTSEFACDSLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP21</accession>
    <name>A0A1D3RP21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_16045_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000715">
        <property type="protein sequence ID" value="SCN47394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="117" mass="13308" checksum="3F89247E81723807" modified="2016-11-30" version="1">MTLILQQTKAEPELVNAIKNYTKVHNEILQEVYAKAIKEFIDSFKNIAPGEHHPIFYASPSAGLTINLKLPEKLKNEAVQLATKEQSSARRLYYTALLRFALNKKLINSKEDIMHGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP41</accession>
    <name>A0A1D3RP41_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Septum site-determining protein MinD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cell division inhibitor MinD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_19938_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParA family. MinD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000764">
        <property type="protein sequence ID" value="SCN47453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010223">
        <property type="entry name" value="MinD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01968">
        <property type="entry name" value="minD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="9">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="269" mass="29467" checksum="3FDEC5B87EC1B9B8" modified="2016-11-30" version="1">MARIIVVTSGKGGVGKTTTSAAIAMGLAKKGHKTAVIDFDVGLRNLDLVLGCERRVVYDFVNVINNEANLNQALIKDKRCNQLYILPASQTRDKDALTKEGVGKVLEELSKTFKYIVCDSPAGIERGANLAMYFADDAFVVTNPEVSSVRDSDRMLGILSSKSKRAELGEDPIKEYLLLSRYDPKRVKLGAMLSVEDVQDILSLHLLGVIPESQSVLSASNAGEPIILDETSDAGQAYADIVDRYLGEDKPHRFIDEEKKGLFGRLFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP46</accession>
    <name>A0A1D3RP46_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ORF">BAZMOX_90202_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="FMJP01000774">
        <property type="protein sequence ID" value="SCN47470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="13"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="255" mass="28455" checksum="851EBE6A9D5FADE0" modified="2016-11-30" version="1">MSITIKTDAEIKKMRIAGKLAAEVLEFIAPYVVPGVTTNKLNQLCHDYIIDVQNAIPAPLNYHNFPKSICTSVNYTICHGIPNEKNAKKNGDIINIDITVIKDEYHGDTSKMFYVGEVTPYAKRLCVITQECLMLGIEQVKPGCTLGDIGYAIQKHAESNRYSVVQEFCGHGIGKKFHEEPQVLHYGKPGEGATLKAGMIITIEPMINIGKRHMKVLKDGWTAITKDRSLSAQWEHTILVTPTGYEVLTLRQEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP55</accession>
    <name>A0A1D3RP55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_134783_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000780">
        <property type="protein sequence ID" value="SCN47480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="8"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="217" mass="23970" checksum="15E6560F745E7F26" modified="2016-11-30" version="1">MDVWFLVCSKGGVGKSTISTNMAVCAVRAGKKVLLVDLDEKQKSAANWWKRRETEDDIKAVIVPHDIEKVKEIYVFAQKQGYGLVIFDTKGASDTLHNVIIGFATLCIVPVQPSVFDLEAIPSTANMIKSLAKPFTILVSRCPPVGNEFEKLRLGLTAHGLVCPYSTVERKVYRHAAALGLGVGEYDEKDKAAEEVKNIYDWLVKTEEKQNSLKVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP73</accession>
    <name>A0A1D3RP73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_09742_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000759">
        <property type="protein sequence ID" value="SCN47446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4690" checksum="AD170134B383607F" modified="2016-11-30" version="1">MGTLSNDSYKPEKEESLLRQGRIHSLLNPRLPVFSRYTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP87</accession>
    <name>A0A1D3RP87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_140607_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000662">
        <property type="protein sequence ID" value="SCN47318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="123" mass="13564" checksum="8C6E5C45D829A39F" modified="2016-11-30" version="1">MGKERGGLGIEDIGQESSIDLEGAISSSKTHKTPTAAIETEIKAASEKAGFPSRQGRTKRIKPKSPYTIQSNLKTRAGVKELFQEVGARLGVFDQETFEKALFALLEKEKMQDLEAELRELIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB6</accession>
    <name>A0A1D3RPB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MG(2+) CHELATASE FAMILY PROTEIN / ComM-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_10012_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000806">
        <property type="protein sequence ID" value="SCN47533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mg_chelatase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Mg_chelatase_C" evidence="2">
        <location>
            <begin position="64"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="110" mass="12002" checksum="500E5FAEFD75BAD7" modified="2016-11-30" version="1">MISAMNPCPCGYLGDPSGRCRCTSEQVSRYRAKISGPLLDRIDMHLEVPRVSHEVLRKGSAEGEETSAVIRARVIKARALAVARSGKANSLLRAKEVKQVCTLSEQGHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC5</accession>
    <name>A0A1D3RPC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_37982_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000776">
        <property type="protein sequence ID" value="SCN47472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="75" mass="8683" checksum="6C8BECDD7B4DF3B4" modified="2016-11-30" version="1">MSQLLLLGTSACHLCEQAESLAVQLKLPFTKVDIAEQEQWQERYAIKIPVLLDLESQKELCWPFSSADILHLWER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE4</accession>
    <name>A0A1D3RPE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_123298_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000860">
        <property type="protein sequence ID" value="SCN47605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="66" mass="7456" checksum="28CBCA11DFFFCB4E" modified="2016-11-30" version="1">MGLALKDTEHHCYGDYLHWADNNYELIDGEAYFMAPAPNLEHQEVAGDSLFSVTFSFSPVKNVVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK0</accession>
    <name>A0A1D3RPK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trypsin domain lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_134085_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000879">
        <property type="protein sequence ID" value="SCN47621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="223" mass="24222" checksum="D126B7F09A9FB6FE" modified="2016-11-30" version="1">MNIYIQLVAPYSNQDAPGKPAFALGWGAVISSGDLFPLDLRQVVLPLVSNTTCSFSMNEDISDDMLCAGDGLGLRDTCSGDSGGPLIVFDSESHTWRQAGITSWGNGCAEFGTYGVYTRTKNYAEFISSQICSAQEIPVSPSLRLNINANIVSLDWLNENGTEGYRLNYAPYPDAQYIASMDMNLLTHFSAGLVSGSAYYVAITSYNNNCLSDYSNIEHFVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP2</accession>
    <name>A0A1D3RPP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.117</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tetrahydrodipicolinate N-succinyltransferase</fullName>
            <shortName evidence="9">THDP succinyltransferase</shortName>
            <shortName evidence="9">THP succinyltransferase</shortName>
            <shortName evidence="9">Tetrahydropicolinate succinylase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapD</name>
        <name evidence="11" type="ORF">BAZMOX_00742_2</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA</text>
            <dbReference type="Rhea" id="RHEA:17325"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15685"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="EC" id="2.3.1.117"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.117" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000881">
        <property type="protein sequence ID" value="SCN47624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008666">
        <property type="term" value="F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.166.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00811">
        <property type="entry name" value="DapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005664">
        <property type="entry name" value="DapD_Trfase_Hexpep_rpt_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023180">
        <property type="entry name" value="THP_succinylTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037133">
        <property type="entry name" value="THP_succinylTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14805">
        <property type="entry name" value="THDPS_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00965">
        <property type="entry name" value="dapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THDPS_N_2" evidence="10">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="272" mass="29124" checksum="EC14710BA24C30DE" modified="2016-11-30" version="1">MNELEKIINEAFENRAEISPTTVSDEVRNAVKESINLLDSGKARVADKASGEWVVNQWLKKAVLLSFRINENRVMDGGAARYYDKVETKFASYTPEDFAEAGVRVVPNAVARHGSYVAPGAILMPSYVNIGAYVGAGTMVDTWVTVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEIVEGVVVEEGSVISMGVYIGQSTKIFNRMTGEITYGRIPAGSVVVSGNLPSKDGTHSLYCAVIIKHADEKTRSKTGINELLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT1</accession>
    <name>A0A1D3RPT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-alanine aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_03760_3</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.21" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000816">
        <property type="protein sequence ID" value="SCN47549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047810">
        <property type="term" value="F:D-alanine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="279" mass="30922" checksum="DB04682A15F7498C" modified="2016-11-30" version="1">MHEKNVYLNGEYLPLAEAKISVLDRGFLFGDSVYEVIPAYMGNLFCFAMHLQRLNDGLKAIRLPISYTTEQWLDILQPLLIEGDAQYIYLQITRGVADKRDHSFPLSCTPTIFAMCNPIMPVLGEQGVQAITLDDVRWKLCHIKATTLLANILLRQKAVDEGAAEAILINEGYATEGAASNIFVVIDGVLITPPKTNEILSGITRDVIIHLAKANHIPVTEDVISLEALQQASEVWLTSSTREILPVTILDHEPIGNGQVGPVWQAMNGLFQEYKQVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT3</accession>
    <name>A0A1D3RPT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rep_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_06810_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000897">
        <property type="protein sequence ID" value="SCN47656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="17"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="379" mass="44906" checksum="23DECC5CED0DAE45" modified="2016-11-30" version="1">MRVVNRDFSLGEYGQSWTKLERYLFIEIYNVIKDFYLSTSDENIKTFSSESILLTLPVNRLDKSLFKPSQKNRDLMKAAEGLSKKQINLKALGDDEQWYFRFISMFPEICYEPLKDRNKILIRIPNSIYEEMVPIESYCLLDLKLLSEFGSGNTIRLYEIFKSYAFKKKFDIGFNELRKQLGFFNEGNYQEWKYFNAKVLKPAVKDINSYKQFDIEVFYEKKRGLDKVSFTIKTHIIQDVSKIQVLNLNEEINGLTRIPNLIQKKYIETVLFFCKKKHSISNEIELTEWIISDLINQQIKLEKSFNFKHSMNSISKQIRNGNYTKPYSHKHLVIDEISFDPIIYEEIKKMVSEGKHDNIKDEYSSEQIRANHFGFILDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU2</accession>
    <name>A0A1D3RPU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cytoplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_21397_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000944">
        <property type="protein sequence ID" value="SCN47720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009362">
        <property type="entry name" value="YhcG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041527">
        <property type="entry name" value="YhcG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17761">
        <property type="entry name" value="DUF1016_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06250">
        <property type="entry name" value="YhcG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1016_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="YhcG_C" evidence="1">
        <location>
            <begin position="170"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="333" mass="38581" checksum="7AD6350075D9B742" modified="2016-11-30" version="1">MSKDMQPSMNFQIVLSQIQEAKQKAYKQVNAVLVELYWNIGKHISEQVKANRWGKGIVEELAQFIHRREPNLQGFTARNMWRMKQFYETYCDHEKLSAVLTQLSWTNNLLILSAAKSEEERAFYITLTIKENYSSRELKRQIKSSTFERVMLANEKLSAVMTELPQDTKNVFKDSYTLEFLGLGATHSESDLQQSLVASLKAFILEIGRDFCFMGQEYKVQVGNKDFSIDLLFYHRSLQCLVAFELKIDEFSPSYLGQLEFYLEALDRNVKKDNENPSIGVLLCRQKNDEVVEFALSRSMSPAVISKYEPQLIPKELLQNKLNELYEMLGAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV0</accession>
    <name>A0A1D3RPV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_20798_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000894">
        <property type="protein sequence ID" value="SCN47652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4123" checksum="D0EC8D4F8334DEA9" modified="2016-11-30" version="1">MHKLFLLTHKYIDLSIKVSIYIALLGHGALEESAILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ02</accession>
    <name>A0A1D3RQ02_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="12">ASA dehydrogenase</shortName>
            <shortName evidence="12">ASADH</shortName>
            <ecNumber evidence="7 12">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">asd</name>
        <name evidence="14" type="ORF">BAZMOX_11064_2</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 12"/>
    <dbReference type="EMBL" id="FMJP01000947">
        <property type="protein sequence ID" value="SCN47726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="13">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="41"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="162"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SCN47726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="340" mass="37090" checksum="7B1109BC80A2996F" modified="2016-11-30" version="1">MTKKYNVAIVGATGAVGEAMISILEERKFPVDRVYALASERSVGKRISFNGRSLKVEDLAKFDFSKANIGLFSAGASLSEKYAPIAAAAGCVVIDNTSQFRYDDDIPLVVPEVNPEAIAQHTVRGIIANPNCSTIQMLVALKPIHEAVGITRINVCTYQAVSGSGKEGIEEVVSQTSQLLNGKPIQTKVYPKQIAFNVLPQIDVFMDNGYTKEEMKMVWETKKIMGDDSIQVNPTAVRVPVFFGHSEAIHIETRAKITVEKVRELLAAAPGITVMDERVEGGYPTAVTESSGHDDVFVGRIREDISYEKGIDLWVVADNVRKGAALNSVQIAEELVKNYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ21</accession>
    <name>A0A1D3RQ21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MxaJ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_18015_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000887">
        <property type="protein sequence ID" value="SCN47639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022448">
        <property type="entry name" value="Quinoprotein_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03871">
        <property type="entry name" value="ABC_peri_MoxJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920288" evidence="2">
        <location>
            <begin position="21"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="64"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="317" mass="35563" checksum="EE130A9EEDFD5356" modified="2016-11-30" version="1">MSFAKKTQTLLSVLAFSSLAACQTAEKANTLEQPAATEISKDAEAAKIIKKPSTTNKNPRDEKKFRVCADPLNPPYSSKKLDGFENKIASLFAKQLGQEVEYYWFPQRIGFVRNTLKSTIGDTQEFKCDVIMGVPSGFDFTATTKPYYRSSYVLLIAKGRGWDNITIPEQLRSLPLAKQASLKIAMFDRGPGTAWLQKSGLLEQGVPYQTMTGDSDNNTAMMIDKELQAGNIDMVILWGPMAGYLMTQHPDAYKLIPMKSSLNMKFDYSMSMGVRYPDKQRKALLNDLITKNQQAINKILESYHVPLLPIPEKKKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ28</accession>
    <name>A0A1D3RQ28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_07461_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000893">
        <property type="protein sequence ID" value="SCN47649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5036" checksum="23951D65777080B2" modified="2016-11-30" version="1">MRSLRAKEKDKTSGEIDSAVQDDGALVRMLNKKSSPILTPATTIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ31</accession>
    <name>A0A1D3RQ31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PREDICTED: similar to proprotein convertase subtilisin/kexin type 9 preproprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_45812_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001008">
        <property type="protein sequence ID" value="SCN47800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920268" evidence="6">
        <location>
            <begin position="33"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="164"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="444" mass="47752" checksum="BC56DE8E472D4F05" modified="2016-11-30" version="1">MKKGIVMKKKCSKILMFILMIVSSIFFPSAYADEDDDKKSYIIIFKQAELVENEAPLQTLIQNGADTSETMSSGTDEAKQDIADELNLDGEVIDIYDGINGILVNIDLTEALRLSALDQVESIEEDSTIPEAAFSTQKNSGWGLGRIHQSTATSDNSYQYEYDGSGRTIYVLDSGLNINNSKVAAEFGGRASVIWDVNFAGKGEDCTGHGSMVSSAAAGKTYGVAKGVTLKMAKISVGCRRSTSIAATVKAINWIAENAPRGSIVNWSYGFKDRGPYIRIPCIRTYSSPALEAAIKKAYNAGMFVVIPAGNDACDTKNYSPTNIPESFVVGATSNLDFANGKDRIASFSRKGTNISGFAPGTNLLLMNKDGHPISKSGTSFSAPYVAGTIAVVCEHEGTRCESGNEDMATLYRVFREAGTLNTVTNTDGTTLTGATSRFIRQQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ36</accession>
    <name>A0A1D3RQ36_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_47804_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000986">
        <property type="protein sequence ID" value="SCN47774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="124" mass="14241" checksum="0568EFA3FBA91E11" modified="2016-11-30" version="1">MHVDEFQDTNTIQYAWLRLLTEGKDNLFVVGDDDQSIYGWRGAKIENMFNFQKQYPNHLLVRLEQNYRSTGNILKASNALIACNEGRMGKALHTDDGDGDLISLYSAFNEQDEAYFVVERIENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ94</accession>
    <name>A0A1D3RQ94_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_60641_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000863">
        <property type="protein sequence ID" value="SCN47607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025758">
        <property type="entry name" value="Fic/DOC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026287">
        <property type="entry name" value="SoFic-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13784">
        <property type="entry name" value="Fic_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038925">
        <property type="entry name" value="AMP-prot_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="106"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="190"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="191"/>
            <end position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="228"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR038925-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="351" mass="40491" checksum="06475B8B7E1F06CA" modified="2016-11-30" version="1">MMQKLSAPTINTDDPAILMALIKAHRPLAELKGIVKSIPNQQILLSTLTLQEAKDSSEIENIITTQDELYKHTLRSDLSNLATKEVANYNRALQVGFQSVKESGLLTLNTIRKIQANLEDNRAGFRKQLGTVLKNEQTGEIIYTPPEPQHIPELMGDLEKIINQSPPQYDPLVQMALIHHQFESIHPFYDGNGRTGRIINILYLVKTGLLDPPVLYLSRYINRTKTEYYQRLQHVRDNNDWQGWIIYMLKGIESTASQTITLVEAIKALLQKQKHAIRNQFKFYSQDLINNIFHHPYTKVQFLERDIRVSRATATRYLDALADYGILEKHKLGRENYYLNRELVDLLFNIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB9</accession>
    <name>A0A1D3RQB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_07384_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001038">
        <property type="protein sequence ID" value="SCN47854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="72" mass="7997" checksum="5C4162CFED71E603" modified="2016-11-30" version="1">MDEENTILSDAELAMQEACAKLNAYVIRSMSSDNFSMVDFLAQQQVIRSLDNCDAATKKLEALLPPPFTIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD4</accession>
    <name>A0A1D3RQD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_30116_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001076">
        <property type="protein sequence ID" value="SCN47901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022529">
        <property type="entry name" value="DUF3530"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12048">
        <property type="entry name" value="DUF3530"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920291" evidence="1">
        <location>
            <begin position="22"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="256" mass="29341" checksum="9E4AAC1496CB83AB" modified="2016-11-30" version="1">MLIRKITITLIFCLISLNLYATDAAREAQYAKEISAGNARDEVIWLGESNKRFLVLYRESEKSGFKGTAILLHHMGGHPDSDPLIYTLRRELAKHNWATFALQMPLREIGAPAVDYYSLFPEAKQRINEATRHLADHGAESIVLIGHQLGALMALYAQANEPMPEIKALVTIGLNAPETDNKNAQTFELIKQLRIPFYDIYGEQDAEDVVYSARERRISARNNKQYRQFQLNRASSPYWQDQTLIVKRIYGWLSHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQF4</accession>
    <name>A0A1D3RQF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_201620_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001054">
        <property type="protein sequence ID" value="SCN47876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="53" mass="5961" checksum="87B5166C5B057E45" modified="2016-11-30" version="1">MGISFRTLPLAKGFWCDWLACPMTEGRQAGQRRSAERESHSWGGCEDTSGENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQH2</accession>
    <name>A0A1D3RQH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division protein FtsK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_07852_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000955">
        <property type="protein sequence ID" value="SCN47738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="527"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="170"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="544"/>
            <end position="551"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="882" mass="96330" checksum="E16CEF89D0305ED6" modified="2016-11-30" version="1">MAVGLILLVLVGLVLLVQTAGSSAEEVELADIFAVLTLIMIPCVSVFAVLVALEKYAGISCLRGVEAVGKYTLMGLDWLYVTVQGWFGIEVKKTNRHVDRPSKGTKKTKGGQEKFSRVKPVIKSTASEIVEPVFSEAMLAENLNNERVFNFEPVHSQDPLAEEQQNPIAMDSADPATNKNQMDQQGDSVKEVDSSLVTDNLHSEREISTEKQARETTNFSDTPEVIDFGSDLKSFFQDKQGGAADMAPPPVEPLINVPIADAEALFDRSGLENTEATEEEQEEDISLAENMAHDNKPELSPSIAEIMANLSTYTPANQTPDKPLAEDVESIENEITKAQPKRSIAEIMATATHLATESIEDKNALAKQEAARLIASFANNAAKPDFNKSQYILPDLELLDEHQQSIHSYTKDELDEMSDSVERVLLDYKITVEVVGAYLGPIITRFELSLAPGIKVSRVTGLAKDLARAMLVTSVRVVEIIEGTPFIGLEIPNQERELVSFREILSSEEFQQAKSPLTLALGKDVSGDAVVADLAKMPHLLVAGTTGSGKSVAINTMILSMLFKATPEQVRMIMVDPKMLELSIYEGIPHLLTPVVTDMKEAQNALRWAVAEMERRYKLMAKVGVRNLAGFNQKIEEAAAKGETIRDPLYQLVDPLEEGQTFPVLSTLPSIVIIIDELADMMMIVGKKVEELIARLAQKARAAGIHLILATQRPSVDVLTGLIKANVPTRISFQVSSRIDSRTILDQGGAEALLGNGDMLYLPSGTSVPTRSHGAFVDDHEVHAVVDFLKSLGGANYLDEITKDESVETTSNHEAAGDEVDALYADAVSFVMDSGKASISSVQRRFKVGYNRAARMIDQMEEENIISEPEGNGSRRVLNKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQI2</accession>
    <name>A0A1D3RQI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00666_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000962">
        <property type="protein sequence ID" value="SCN47748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014094">
        <property type="entry name" value="LpoB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13036">
        <property type="entry name" value="LpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="317" mass="35376" checksum="8CF745A2A92268A2" modified="2016-11-30" version="1">MDPTLHTQSKGDYESDVWHHAKREVALPQNYSQKNYKRIVLATNFFANKDYNTYGPTPIEVLSTMLETELSKLKRFTLASRHLGQKGKWAEKKFQDMGTTSARSTVRIGNGLNADFGLTGGISSIKEEYDRGSKNEVLYIVRIDYQITDFETDEIIEADMAEGRAKRSIFRLPSGKVIGGFSDSDESEAVKQAAINALKVVANKLGNKLPIGCQVTGIRGNRFGCDRGYEEGFMGKQMVTIYIDDNGIDLPLAVAEASPGAHKTSGKIIAWNNDKDEYVQDIIRQIRANPSFARQNDLFAVSLAMPTPPEWDSNYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQK4</accession>
    <name>A0A1D3RQK4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Toxin CcdB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cytotoxic protein CcdB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protein LetD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_33220_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CcdB toxin family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001084">
        <property type="protein sequence ID" value="SCN47912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008657">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006276">
        <property type="term" value="P:plasmid maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002712">
        <property type="entry name" value="CcdB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01845">
        <property type="entry name" value="CcdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="106" mass="12079" checksum="B74DD5F841392FCF" modified="2016-11-30" version="1">MMPQFTLYKNENKNSKKAYPYFIDVQSDLLVDLNSRLVIPLSAQETLDNLNAKKLCPTIEIDEGVFVLLTHQMTSVPYSTLKNKVTSLEHYRYDILGAIDLLLTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQL0</accession>
    <name>A0A1D3RQL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_340680_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000989">
        <property type="protein sequence ID" value="SCN47778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4827" checksum="16A476519F18C1D6" modified="2016-11-30" version="1">MRTATAVHFGLANFPVAYCGLKIITSLSLRFPDFQRAIKQQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL46</accession>
    <name>A0A1D3RL46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_18013_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000002">
        <property type="protein sequence ID" value="SCN46392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="207" mass="24259" checksum="8A07CE1C25891ECD" modified="2016-11-30" version="1">MFESLVKRLLQGEFICEITDEAGFQYLQNPENLFQVEDYLQRLNYRLASTQNKLSFYAAYIEIDNAARQDIRKVFQQFRLELHPVVEWLDMMMACLKQDTVLSPGDTLAFSSLLQVIENNQALADRLQAFAKFKDFTSNEDSIKGRLEKLLSTLQKWGYLQLANRDTLIYQVTGKLDYFYQSLQLIQEHEEIPIEQGEEESTQETLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL74</accession>
    <name>A0A1D3RL74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01013_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000006">
        <property type="protein sequence ID" value="SCN46394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="52" mass="5861" checksum="DED539444A697F76" modified="2016-11-30" version="1">MVIVASGSGLSGYILRARKERLSRKKQLALNETKLLTDQSEKSSLWGRLKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL81</accession>
    <name>A0A1D3RL81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01179_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000036">
        <property type="protein sequence ID" value="SCN46433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="7114" checksum="842030B627D98D57" modified="2016-11-30" version="1">MRKPIATQQKKRKTPLISYLVNDKHISATTIATHAATEFGLPFFDLSAVDKSILPSGLVSEKTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL97</accession>
    <name>A0A1D3RL97_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_10981_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000039">
        <property type="protein sequence ID" value="SCN46442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="154"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="337" mass="36274" checksum="F5762889B96250AC" modified="2016-11-30" version="1">MAIKIAINGYGRIGRCVVRAIYEANRKAEVEVVAINDLGDTATNAHLTQYDSVHGKFPFEVTMDGDYMIIDGDRIRVLAERDPSKLPWAELGVDVVHECTGFFATKEKASAHLSAGAKKVIISAPGGNDVDATIVYGVNHDILKASDTVISNASCTTNCLAPLVKPLLAGIGIETGLMTTIHSYTNDQVLTDVYHKDLRRARSATQSMIPTKTGAAAAIGLVFPELVGKFDGFAMRVPTINVSVVDLTFVASRPTSKEEIDGLLKTASEGPLKGVLGFNDKPLVSMDFNHDPASSTYESSFTKVTGGVLVKVLSWYDNEWGFSNRMLDTTVALMNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLE7</accession>
    <name>A0A1D3RLE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_08870_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000073">
        <property type="protein sequence ID" value="SCN46493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="232" mass="25660" checksum="CCFC2B8D179AE310" modified="2016-11-30" version="1">MTQAGWNRLQQQLHQREFQPPSSMPPLSLSMVSPVQQQSGMMVRGSTPSPRSNTEFLFPSSTQQQNADKMSIRGPGKLSELLSNRSNIDSPLLRNNSRDGVFESERKENNSVLSPLDSHQSPQPGPGSLSPMEKPQSTTSLDDNDSSRKSDGKKQQKNVILKQLLSQDDTSESDKNDEKSPGDSNMNEAEAKKPNALLKVSFILDLTNLIPPQKKMVCTAFVLTDLPKARNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLH0</accession>
    <name>A0A1D3RLH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translation initiation factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_57941_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000088">
        <property type="protein sequence ID" value="SCN46506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF-2" evidence="3">
        <location>
            <begin position="2"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="179" mass="19764" checksum="FB7A2026DC8594B0" modified="2016-11-30" version="1">MSHEEVEVKVVYGGVGGINEGDANLALASGAILIGFNVRADATARKLIAEKELDVHYYSVIYDAIDEVKKSINGMLAPEIKEKIVGLAEVRDVFRSPKFGAIAGCMVVDGFVKRSLPIRVLRDNVVIYEGQLESLRRFKDEASEVKMGMECGIGVKNYNDVKAGDQIEVFERIEVKREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLI3</accession>
    <name>A0A1D3RLI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_297538_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000033">
        <property type="protein sequence ID" value="SCN46429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="66" mass="7755" checksum="31B9E1F959CE84D4" modified="2016-11-30" version="1">MDETYIKVKGKWVYLYRAVDNRGDTLDFMLSERRDEDAATAFFKQATIMAFLIRSLWIKVGQTMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLJ7</accession>
    <name>A0A1D3RLJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_07213_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000124">
        <property type="protein sequence ID" value="SCN46551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="74" mass="8719" checksum="831B68E23A668DF5" modified="2016-11-30" version="1">MRGDLLKNCTLTLPNEINIHFELLIRSSKPYSNSRTKLLIGGHFDQLKSPKEQNQLEQFFALVERSQIRQKKDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK1</accession>
    <name>A0A1D3RLK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_74407_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000048">
        <property type="protein sequence ID" value="SCN46449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4195" checksum="C22E035449038DEE" modified="2016-11-30" version="1">MMGFKAFHSAQATIAGIETEHMIRKEQLSEDNIPAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK2</accession>
    <name>A0A1D3RLK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfur carrier protein adenylyltransferase ThiF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_53815_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000155">
        <property type="protein sequence ID" value="SCN46585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="79" mass="8431" checksum="DAE7081D4280045C" modified="2016-11-30" version="1">MLPQVDIEGQEKLLNAHILIVGTGGLGSPAAMYLAAAGVGNITLYDNDQVDLSNLQRQIAHYTNDIGTDKVISTQHTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK8</accession>
    <name>A0A1D3RLK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_139167_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000009">
        <property type="protein sequence ID" value="SCN46398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="7092" checksum="1E14EE4C7C2C4989" modified="2016-11-30" version="1">MAKIERIPNSSFPENLSGSSFLAEVTKTWTACFNILLRDELANASDHVERAKGAFSAVSSMSNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL1</accession>
    <name>A0A1D3RLL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase</fullName>
            <ecNumber evidence="9">6.3.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_03205_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.3.2.-" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000127">
        <property type="protein sequence ID" value="SCN46553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02020">
        <property type="entry name" value="Mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005757">
        <property type="entry name" value="Mpl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01081">
        <property type="entry name" value="mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="8">
        <location>
            <begin position="108"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="7">
        <location>
            <begin position="313"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="450" mass="49865" checksum="296B60127D4563A4" modified="2016-11-30" version="1">MHIHILGICGTFMGGLALIARELGYTVSGSDQNVYPPMSTQLTEQGIHLMHGYKAENLTINPDLVVIGNAISRGNPEVEAVLNLGLKYTSGPQWLSEYVLQDKWVLAVAGTHGKTTTSSMLAWILEYQGFKPGFLIGGIPMNFGLSARAGETDFFVIEADEYDSAFFDKRSKFVHYRPRTVILNNLEFDHADIFDDLSAIKRQFHHLVRTIPGQGLIIAPQADANVQDTLTMGCWTPVQETAIGQQADWQATLVQEDGSQFEVLFANEKHGQVEWGLTGLHNVHNGLAAIAAARHIGVLPVDAIAALAQFKNVKRRMEVIAKIRGTTIYDDFAHHPTAIKMTLEGLRQHVGSEKIIAVLELRSNTMRMGVHRKELVSALRSADKVIIYQSENVAWDLSELQVYTDKIQICMSIGEIVTKLQQEVAAQSHFLIMSNGSFGGIYQRIKSELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP2</accession>
    <name>A0A1D3RLP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_82098_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000133">
        <property type="protein sequence ID" value="SCN46564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="156" mass="18492" checksum="F09B63BFF03A4874" modified="2016-11-30" version="1">MAIWAQIWKDVKGDNYARGRQEMEKQHKDRTPQDPNYSYELRKKRFMLYAKADVSKNNPIMHISTYRKLMDWFSSRYEQQTKIQVSSGNATETQILVNESFVMYRYPFKLKELIFNRKLQVKREKEAAEAKAAAEAKRRAEIMIPVLEVKQPVNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP7</accession>
    <name>A0A1D3RLP7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="5">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_02676_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 5">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000161">
        <property type="protein sequence ID" value="SCN46590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DHAP_synth_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PTHR21225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="6">
        <location>
            <begin position="43"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="356" mass="38843" checksum="F447BC79CE51FA81" modified="2016-11-30" version="1">MQDQINTDNLRIRKTRGVMAPVLIHDELPLTEVIAKTIQQARQAVHNILSDQDDRLVVVVGPCSIHDPKAALEYASKLRVIKDKLKQDLHIIMRVYFEKPRTTVGWKGLINDPDLDGSFNINKGLRIARKLLLDLNSQGIPAATEYLDLITPQYVSDLIAWGAIGARTTESQCHRELASGLSCPVGFKNATDGTIAIANDAIKAAMNPHHFLSVTKEGNSAIFSTTGNEDVHIILRGGSGGPNYDAVSVDKVARGMEKSGLKANIMIDLSHANSLKQCQRQLLVGEDVAEQVARGDHRIMGVMIESHLHAGRQDVVAGQALVYGQSITDGCIGWNDTETLLNNLAVAVQSRRTVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT7</accession>
    <name>A0A1D3RLT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_394098_0</name>
        <name evidence="2" type="ORF">BAZMOX_421092_0</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000114">
        <property type="protein sequence ID" value="SCN46539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000320">
        <property type="protein sequence ID" value="SCN46844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4684" checksum="521F3164DFA64052" modified="2016-11-30" version="1">MGFKAFHSAQATIAGIETAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU0</accession>
    <name>A0A1D3RLU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane vitamin B12 receptor BtuB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_39362_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000173">
        <property type="protein sequence ID" value="SCN46614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TonB_dep_Rec" evidence="1">
        <location>
            <begin position="19"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="304" mass="34458" checksum="917DB78CAFA24D9C" modified="2016-11-30" version="1">MMAGGNSYLELLNFTLTPDHLLTLGYDFQNDKVISDADFAKTKRNNHALFMQYQGEFAHHQITLAYRSDFNQQFGQFSTWNAAWGYAFDNGILVSASYGTAFKAPTFNELYFPGFGNDTLNPEKSESYEVGVRGKHDFWHWSLNGYLTYIKNLIAYDSSIFAPNNISKARIMGLEAIVGGQLYGFDIEMNYSALNPESMDSASFSNVLPRRAQHTFRLDIDRQLGAASIGSSLNVEGRRFDDLQNTNRIDGFVTWDLRAEYTFYESLTLQSSVKNILNTQYQTVAGYNTPSVTVFFNLRYAPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU9</accession>
    <name>A0A1D3RLU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_196314_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000187">
        <property type="protein sequence ID" value="SCN46640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5781" checksum="92F59203BF69FE63" modified="2016-11-30" version="1">MGFKSLFFLVVSGFKAIKKMFRVGRPLKHTLQLTIKREAINSLFDGCYAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM10</accession>
    <name>A0A1D3RM10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbfA</name>
        <name evidence="2" type="ORF">BAZMOX_57941_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000088">
        <property type="protein sequence ID" value="SCN46507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="125" mass="14136" checksum="77A8ADD4602778B6" modified="2016-11-30" version="1">MAREFKRSSRVAAQMQKELAIILQQGIKDPRIGFITVNEVELSKDLSSAKVFITALGADEQGQKDNLKLLNEAAPYIRSEVGKRMRLRSVPYIKFHYDTSFENGMRVSELLAQFPAVSDAEEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM32</accession>
    <name>A0A1D3RM32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_354429_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000233">
        <property type="protein sequence ID" value="SCN46714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="4897" checksum="F3B7910ECC369661" modified="2016-11-30" version="1">MSVIFMKVIVSLKLKSFSHGENEFFGKTVKRGSGGVEGFGGRTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM46</accession>
    <name>A0A1D3RM46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01011_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000111">
        <property type="protein sequence ID" value="SCN46537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4565" checksum="82AD6B28E89D89CA" modified="2016-11-30" version="1">MFRDIFCLNSGESLFLRKLVLGIRAQASGKNLTRLLMPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM56</accession>
    <name>A0A1D3RM56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_10183_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000264">
        <property type="protein sequence ID" value="SCN46760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="4"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="3">
        <location>
            <begin position="55"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="327" mass="34196" checksum="A4EF5418B8FC5694" modified="2016-11-30" version="1">MQSLKALSAFAVSFGKGNLTARSRFSPTDEIGVMAVEFDRAAANLQNIMTSVNQHSRDLAKHAEQLSSTVEQNLTGVRQQKENTEQVASAITEMSATVVEVSRNASSAAVAAGDADNQANEGKRVVSEAVSSIGSLAGEIDQATTVIQQLEADVGDIGSILEVIRSVSEQTNLLALNAAIEAARAGEHGRGFAVVADEVRTLASRTQSSTNEIQTMIEKLQAGAKSAVIAMGASQKMAGKSVERATDSGIALTAITQAISTINDMNAQIATASSEQSSVTEEINRNIIGISEIADSSVTTANNTLTASRDLARLSEELEALVGQFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM78</accession>
    <name>A0A1D3RM78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_79202_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000280">
        <property type="protein sequence ID" value="SCN46780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4575" checksum="9B8D33C98CFE238E" modified="2016-11-30" version="1">MQNFLPQDVLTKEIFTQWMEIIRQIVDRPVPEVSCIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM93</accession>
    <name>A0A1D3RM93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="4">AGPR</shortName>
            <ecNumber evidence="4">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argC</name>
        <name evidence="7" type="ORF">BAZMOX_48922_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000211">
        <property type="protein sequence ID" value="SCN46679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="6">
        <location>
            <begin position="3"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="344" mass="36978" checksum="C45BFE91B33A6DE3" modified="2016-11-30" version="1">MIRAGIVGGTGYTGVELLRILALHEQVEVAVVTSRSDNGLRVDALYPNLRGSIDVSFSKPDVDSLATCDVVFFATPNGTAMLMAEQLLARNVKVIDLSADFRIKDATEWSTWYGMEHACPDLIADAIYGLPEINRVQIVDANLIACPGCYPTAVQLGFLPLIENGLVDVKHLIADVKSGVSGAGRKAAVPSLMSETGESFKAYASAGHRHLPEIRQGLSLVAGKSVELTFVPHLVPMIRGIQATLYAQLKRDSVDQLQALYEQRYANEPFVDVLPVGTHPDTRNVRGSNNCQIALVVPQGGDTVVVLSVIDNLVKGAAGQAVQNMNLMLGFNENQGLQTIALYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC1</accession>
    <name>A0A1D3RMC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_432973_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000323">
        <property type="protein sequence ID" value="SCN46845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4713" checksum="4102D8649AC8DAB6" modified="2016-11-30" version="1">MLDFNDFFYLKMDKNRTKNHQDTLAIIQNQCVMILSYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME0</accession>
    <name>A0A1D3RME0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_458472_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000312">
        <property type="protein sequence ID" value="SCN46824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="4838" checksum="B445121253A8AAF2" modified="2016-11-30" version="1">MSDYKSILHGFLENPVKFKTGKVGSNARAIGAPSYAENQGNGAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF3</accession>
    <name>A0A1D3RMF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_84593_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000339">
        <property type="protein sequence ID" value="SCN46871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="47" mass="5273" checksum="1A388B0A6649A1B1" modified="2016-11-30" version="1">MNTLMLLAIVLLLLITGIAVRAYVQERHCWKDIKVKASQSGINGFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ5</accession>
    <name>A0A1D3RMJ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03651_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000246">
        <property type="protein sequence ID" value="SCN46728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="57"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="579" mass="65429" checksum="4B7A18AF0934B639" modified="2016-11-30" version="1">MLEFISTLKQRYQTIQLGLVQQSIQWSHYQECIEQLILIEAFLHKGHLINNKMHPLHIAVIGPTQSGKSTLVNLLLNQEAAGVSPLAGFTVHPQAFSADLSNDALIEVAEHFSGFQKVEQFSLSPEKYNSYSLTPISSAQLSGCMLWDTPDFDSIDAQSYKEGVLKTLALADVLVLVVSKEKYADQSVWDILALLEPLNQSLLVVINKLVADSEQLIIDSFIERWQQVRSDSPPPIFPILFAKDHNLINQQAGLNDLLQSSIKQVKRKNYDQAAYAFIRQNWAEWVAPITLEIEAQAHWQSIISQTLKDALDIYKRDYLDHPQHYDTFQNALAKLLTLLEVPGIAKVLMQSRKVLTWPLRKVFSLGRKVSKATYPETKETEVLQQIAEHVLLQVSDKVLDQIDQVQGNNKWWKQINSQLRQDKTLILDDFAHKTELYHENFKQDIEATAQGLYTKLEEHPAILNSLRATRVTTDAAMLALTVQAGGIGLHDLLIAPAMLSVTSYLAESAVGSYLHRAEAELKQRQLHTVKELLFTQVIHQVLQKLPEEMAQTTHFNISAEQLATAEAQLKIKPHGLRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML5</accession>
    <name>A0A1D3RML5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase_S8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_02753_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000257">
        <property type="protein sequence ID" value="SCN46748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04847">
        <property type="entry name" value="Peptidases_S8_Subtilisin_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034074">
        <property type="entry name" value="Y4bN_pept_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="281"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="823" mass="92686" checksum="923A91EDCE2DEBCA" modified="2016-11-30" version="1">MSENITERLPHLFIKDTAVSSRYTNPASGGGGGEINAPPRDRQSHAQQLLNQVEQIQQQESKLIQEQKAFGLEVNNGICLAFESEQNFRLKFQSLDAQNSGIELCTVREIDKKIIATVFVPEGKLTHFLKKITQYKEEHTRTGKPKNKDLVEGINAIKLAALEALWTDNLELLPANNDSIWWEVWLRRSSKIDFEAFLHDHANQLQMKVSKEAIRFLDRTVILVYGTKQQMSRSINLLGSIAEVRKVKDTADFFTRMNRIDQQEWINNTVEQLTLPAGDAPRVCILDTGVNDGHPLLSPATKGTHSYSPVWGTDDPDGHGTSMAGLALYGDLTEILATTIPFSHTHWLESVKIIPNAGEQNDDYLYGAITQESIARVEIDDLSQRIYCMAVSATKDRDRGRPSSWSAAIDAITSGYTDEQQRLVVLSSGNTDSSYRHQSPESNMSDEVHDPGQSWNALTVGGYTEKVWIDTVENPGWEPLAQAGDLSPASCTSMDWQKTWPIKPDIVMEAGNMAINPAYKQADYIDEALQLLSTGHKFSTGKQLVSFGDTSAAAALAANLAAKLQAQYPEYWPETIRALMIHSAEWTSAMRSYFEPFNTKDKYRQLLRYCGYGVPDEQALFWSARNELTLVAQDTLQPYFKEERTVKTRDINLHNLPWPSEILQGLPPDTQVEMKVTLSYFIEPNPGSRGWVNKFRYASHGLRFDVRKSLESIDQFKQRINKNARDEAYQRQSISDAEEWQLGSNLRGLGSVHSDTWTGLASALAEKGYIAVYPVIGWWKERPKFERWGNQARYALVVSIKTPEVETDIYTAVKNQIAVPVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM1</accession>
    <name>A0A1D3RMM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV secretion system protein VirD4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_01638_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VirD4/TraG family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000388">
        <property type="protein sequence ID" value="SCN46945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003688">
        <property type="entry name" value="TraG/VirD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02534">
        <property type="entry name" value="T4SS-DNA_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="514"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="565" mass="64247" checksum="08520227EB179513" modified="2016-11-30" version="1">MFAGEGIVIGQTVDGQLLQHNGPEHALVFAPPRSGKGVGLVIPTLLAWKGSVIVYDIKRENWEITAGFRKKFSHVLRFEPTSVSSVKFNPLLEIRKGDNEYRDAQNIAEMIIDTGDPNHKNDHWERTSKALFIAAILHVLYAEKDKSIPGVASFLTDPNRNILQTLTYMMTYKHLGDRPHPIIASMTREVLNKSENELSAVLSTATSFLTLYRDPVIANNIRDSDFAISDLMNLKNPVSLYFTIPVSDAERTKPLIRLVLNQIGRRITESMSHDHSQPDYRHKMLLMIDEFPTLGRMDFLESGLAYFPGYGIRAYLIAQSLNQIEKHYGSNNAILDTSHIRITYGALDEKTAKRISDLLGQSTQVRKMANYAGSRLAPWLGHVMVSEQESPRQLLTPGEILNMPPHANLILIGGLFPYYGRKVTYYNDPRFMKRANLPAPNSEEEQRKEFPKPITHPWVYIEKTEEMSVSHENIDPDGSLDISPVHEDGINTGIDNENERGLDEHELALQMESLEDDRIKDEKEYERDEDRNINNQQAQRRLINQRQQGRLQELSRDQSGGDLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM5</accession>
    <name>A0A1D3RMM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">DNA-directed RNA polymerase subunit omega</fullName>
            <shortName evidence="10">RNAP omega subunit</shortName>
            <ecNumber evidence="2 10">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">RNA polymerase omega subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 10">Transcriptase subunit omega</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpoZ</name>
        <name evidence="11" type="ORF">BAZMOX_00824_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the RNA polymerase subunit omega family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 10"/>
    <dbReference type="EMBL" id="FMJP01000397">
        <property type="protein sequence ID" value="SCN46951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00366">
        <property type="entry name" value="RNApol_bact_RpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003716">
        <property type="entry name" value="DNA-dir_RNA_pol_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34476">
        <property type="entry name" value="PTHR34476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="SSF63562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00690">
        <property type="entry name" value="rpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 10 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="80" mass="8955" checksum="B1B513B57A616CC7" modified="2016-11-30" version="1">MARVTVEDCLDNVGNRFELVLLAAKRARQLEKGAEEFVPRGKDKVTVIALREIAEGHVTNENIDMLHQVGEPSDNYFSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR1</accession>
    <name>A0A1D3RMR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02753_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000257">
        <property type="protein sequence ID" value="SCN46747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4716" checksum="5DF48C6431FAFD09" modified="2016-11-30" version="1">MIEKEHFSMPPDHQQRAAQHFAYKDKNNCKRVYQAINKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR8</accession>
    <name>A0A1D3RMR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_115641_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000431">
        <property type="protein sequence ID" value="SCN46995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="132" mass="15228" checksum="A819E5066323E1FE" modified="2016-11-30" version="1">MQTTPKFILYDYLNENGNNEFKEWTEKLQKSERAKLNVKLDMLASKGSELFPEILTGTPTAGILKLRVKGKVQLRPMLCKGPVNKEHEFTLLIGATERDSKFVPRKSDEKANNRKKIIIENPKRRCSHERVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR9</accession>
    <name>A0A1D3RMR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinyl-CoA ligase [ADP-forming] alpha chain</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_262354_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000263">
        <property type="protein sequence ID" value="SCN46757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ligase_CoA" evidence="1">
        <location>
            <begin position="52"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="190" mass="19928" checksum="925B3050DD85E28B" modified="2016-11-30" version="1">MKVKQYLRKFPKEERMILTGPNCAGTISPGKSMLGIMPGHIYQSGVVGIVGRSGTLGYEAADQLKELGIGISTSVGIGGDPINGSSHRDILEKFEQDDETKIVLMIGEIGGPQEVEAGIYASKQMSKPLVAYIAGLTAPKGRRMGHAGAIISSVGESAAEKVEMLQDLGVMIAPTPSAMGETIAKVLAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT7</accession>
    <name>A0A1D3RMT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_426431_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000427">
        <property type="protein sequence ID" value="SCN46990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="7956" checksum="32886D72CDBF0A2C" modified="2016-11-30" version="1">MEVKMHTTAALDDHVDDEDEHVEDVYTNVASNENTTKYKIPVTELHAYIEKKQINKGFEKEYAVRPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMU6</accession>
    <name>A0A1D3RMU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_28918_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000410">
        <property type="protein sequence ID" value="SCN46966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="306" mass="33849" checksum="0F191903F5229C14" modified="2016-11-30" version="1">MDQVTIERGKTTALIGANGSGKSTLLNLCAFLASPQQGELFFNGSPVKLSDLITYRRRVGFLAQKPFMLCGTVFDNIDLALRIHGKKQRAEKIQRVLRQLDIEHCAGQQAKQLSGGELQKSALARMLVLEPEVLLLDEPFSYLDQSSAQSLELFLRRYAQAVGQTLVFSTHDRLQGFALADEVLALAQGKRVHSPLINLFTGVVWEHVFYSGAMRINLPEGVVSGHHASINPQDIVLSTEALVSSMRNCMQGRIVMIAEEGGSILVNVDTGVIFQVLITYQSLRELNIHLGDKIWLNFKSNSVVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV1</accession>
    <name>A0A1D3RMV1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease R</fullName>
            <shortName evidence="6">RNase R</shortName>
            <ecNumber evidence="6">3.1.13.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnr</name>
        <name evidence="9" type="ORF">BAZMOX_01117_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RNR ribonuclease family. RNase R subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000457">
        <property type="protein sequence ID" value="SCN47035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01895">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004476">
        <property type="entry name" value="RNase_II/RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011805">
        <property type="entry name" value="RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013668">
        <property type="entry name" value="RNase_R_HTH_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08461">
        <property type="entry name" value="HTH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00358">
        <property type="entry name" value="3_prime_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02063">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="656"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="745"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="759"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="782" mass="88823" checksum="B629E97503D0A367" modified="2016-11-30" version="1">MNKNKVKIMSKSSDNNIDFSTVADPYAQREAAKYEQPIPSRELILQLIEQHGKPIRRKQIAEAFSLESEDQLEALRRRMRAMERDGQVLFNRRQQYCLVDKQDLIAGRILSYPDGFGFLKPDDGGEDLFISPREMNQVLHNDRALVRVSGVDRKGRREGKIVEILERNTHQVVGHYMSEHGVQFVKPDNKKITQNVLISKGGSHGAKKGDMVVVTLIKQPTSHHQPIGEITEVLGAHMAPGMEIDVAIRTYDLPCEWPDEVLEQIKSLQKVVAEEAKEGRVDLRNIPLVTIDGEDARDFDDAVFCSKTPKGWKLLVAIADVSHYVQQGTALDLEAKKRSTSVYFPEQVIPMLPEILSNGLCSINPDEDRLCMVCEMIINEQGQVMRTKFFDAVMRSHARLTYNKVSAMLEHDNTKLKKKYQAVLPHLEEMYALYKAMREQREVRGAMDFDTQETQIIFGENRKIEKIVPTQRNDAHKLIEEFMIAANSAAARYLNRKKMPRLLRIHEGPSEEKIKNLKTFLGEVGLHIGGGDKPTPVDYMNLTRTIKGRPDAHLIQTVLLRSMSQAVYSPEKKGHFGLALDAYTHFTSPIRRYPDLMVHRAIRHCLQGKSPESFYCGFPEIALLGEHCSSNERRADDATRDVVSWLKCEFMQDKIGETFPGIISAVTGFGLFVELADLYVEGLVHVTSLGQDFFKFDPLSHQLKGERTGVCYRLGDSVNIVVIGVNLDDKKIDFELLGQQRKTKARTLAADTLDKPAKKKNRKKPKRKKPKHKGKAEKKVHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV2</accession>
    <name>A0A1D3RMV2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ORF">BAZMOX_00289_6</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000434">
        <property type="protein sequence ID" value="SCN47003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="360" mass="39484" checksum="93386E089C168AA7" modified="2016-11-30" version="1">MLLYLFEYLAQFEPSFKVFQYLTLRGILSALTALMISFLVGPSMIRRLSNENIGQSIRQSGPESHYQKAGTPTMGGTLILVGIAVSTLLWGNLENSYVWVALLVTMAYGVVGFIDDYKKVKLGNSDGLSARAKYLWQSVIALTAAIFLYKSALVPAETQFIVPFFKEVVIDMGWTYVLLTYFVIVGTSNAVNLTDGLDGLAIMPTVMVAGALAIFAYLTGYVMFAEYLVIPYIPKAGELVIFCAALVGAGLGFLWFNAYPAMVFMGDVGALALGAALGVVAVLVRQEIVLMIMGGVFVMETVSVIMQVASFKLTGKRVFRMAPIHHHFELKGWSEPHIIVRFWIITVILVLIGLSTLKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV8</accession>
    <name>A0A1D3RMV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_70760_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000350">
        <property type="protein sequence ID" value="SCN46889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="5">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="95" mass="10066" checksum="0D2FB3C35396D8B1" modified="2016-11-30" version="1">MSKLDDTAPHEVLLVLDAGTGQNALSQAEHFNKAVKLTGIALTKLDGTAKGGIIFALAKKAGVPIRFLGVGEGINDLQDFNARDFIDALFKQDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV9</accession>
    <name>A0A1D3RMV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_48536_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000425">
        <property type="protein sequence ID" value="SCN46984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="144" mass="15950" checksum="E9FCFDE77B18667B" modified="2016-11-30" version="1">MPAEAKAALDRAGIDIWRIVTGLATEKLAKVQAEADEVVKSATAERDEALAEIERLEASLEKANSELLEKSEAEEKAKQLDMQVHKLQVSLDASVKAADELKAEIKQLRQANEEKTLELGKMTAILEQNEKLERKIEELNSNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW3</accession>
    <name>A0A1D3RMW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_38472_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000448">
        <property type="protein sequence ID" value="SCN47020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4567" checksum="10C07424F38E58BE" modified="2016-11-30" version="1">MDGLYQHALFYTRQLGAPSYLMKHLGLLSPNIHSHTERIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX5</accession>
    <name>A0A1D3RMX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_115641_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000431">
        <property type="protein sequence ID" value="SCN46996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="34"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="162" mass="18790" checksum="985C0BDB2A84B48B" modified="2016-11-30" version="1">MKELVKTLVKEFGDKEYAHAYMEEFSNMAIAAQIKVLREQREWTQKELAYASGMKQERICALEDIDYDAWTIKTLRKLSKAFDLTLKISFEKFSSGILDISKINSETLKRTSRQEDLSEFYCNDFGTKETLWSKPVTTTNRSLFLVQTSDIAVNAIEHRQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY6</accession>
    <name>A0A1D3RMY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cold-shock DEAD-box protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_78943_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000455">
        <property type="protein sequence ID" value="SCN47033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd12499">
        <property type="entry name" value="RRM_EcCsdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034415">
        <property type="entry name" value="CsdA_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="171"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="378"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="486"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="517" mass="57900" checksum="6B3FB0B9ABA6FDA1" modified="2016-11-30" version="1">MPLLSKIDVKLKATQVLVLAPTRELAIQVAEAFQTYAKHIKGFHVAPIYGGQDYSGQLRMLRRGAHVVVGTPGRVMDHMRKNSLKLDNLKCLVLDEADEMLRMGFIDDVEWVLEQLPTDCQKALFSATMPTVIRRIANEHLDNPEHVTIKVKTTTAETIRQRYWTVSGMHKLDALTRILEAETFDGMIIFVRTKNSTVELAEKLEARGFSAAPINGDLAQNQREKTIARLKNGKLDILVATDVAARGLDVPRISHVVNYDIPYDTEAYVHRIGRTGRAGKAGDAILFVAPREKRMLAAIERATKKRIELMELPSTEVINDKRVNRFKQKITDTLANEELEFYTKVIEQYETEHDVPAIEIAAALAKLVQGDEPLLLKKPAKIKERSERGRERGRNDRERNSVRRKGSTSLSDGLERYRIEVGKDHGAKPGNIVGAIANEAGLDGKEIGQIDMHGEFSIVDLPKGMPAELLKDLQNARVAGQQLRMSVVKESDNIPRQSKSRGGDKSGRKSRRSSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN00</accession>
    <name>A0A1D3RN00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GA15058-PA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_71781_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000449">
        <property type="protein sequence ID" value="SCN47024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920244" evidence="1">
        <location>
            <begin position="24"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="22"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="362" mass="40360" checksum="EF1C8F120CBD9636" modified="2016-11-30" version="1">MKPNSFIKLFFFTILIFSNLTLASSENTDDVPSSSSSWPSMVAIYHSTGGDWKFQCGASLIDKNWVLTAASCMKGVPAKELLVIINEESANVYRSISEIIIHAEYSRHDNDYAMLKIKEVPAWVKPIQIKPIQLAPPYPIESWYWGTTQAKDKYWSNAQTQLKDLSLDGTVKVHELDLTRISNSLCSNNEKMSGRYGKDWITDNMICAGQGLGKKETCDGTSGGPLIMFRGHTNTWMHLGVSSFGGGCAPYGVYARTSKITRWVSDLMCSNEEVPDIPLSLKSDDNGDKTATIKWSSVSGATGYHLNYWTKNDGSDKSSLDLKENYFITPKDSSGKSFYVTVNSYKNNCLSKETKEKYITLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN26</accession>
    <name>A0A1D3RN26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formaldehyde activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_158934_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000466">
        <property type="protein sequence ID" value="SCN47046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014826">
        <property type="entry name" value="HCHO-activating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037075">
        <property type="entry name" value="HCHO-activating_enzyme_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08714">
        <property type="entry name" value="Fae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03126">
        <property type="entry name" value="one_C_fae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fae" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="146" mass="15198" checksum="0857FFF105E1F5D6" modified="2016-11-30" version="1">MMGPRGSAAESAFANCLTNNKDGFSSLLAVVAPNLMVKPATVMFNKVTIKGSKQAVQMFGPAQRGVAMAVADCVEDGTIPADEADDIFISVGVFIHWLAEDDAAIEKNNYDAVKASIKNAVAGTPTAAEVVAQKSTAQHPFAANKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN47</accession>
    <name>A0A1D3RN47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transketolase</fullName>
            <ecNumber evidence="3 8">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_20256_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="FMJP01000504">
        <property type="protein sequence ID" value="SCN47093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="661" mass="71245" checksum="FF18FD5DF5D41A4A" modified="2016-11-30" version="1">MSSRRELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWNDHLKHNPANPEWSDRDRFVLSNGHGSMLIYSLLHLSGYDLPMDELKTFRQLHSKCAGHPEYGYAPGIETTTGPLGQGITNGVGFAMAEKLLANEFNRPGHNIVDHNTYVFIGDGCLMEGISHEACSLAGTWGLGNLIAFWDDNNISIDGHIDGWYTDDTVKRFEAYGWHVISVDGHDSDSINAAIVLAKAEKDRPSLICCKTIIGFGSPNKSGSHDCHGAALGDEEVALTRKELGWTSAPFEIPADIYAGWDAKATGAEKESAWDAKFAAYAKEFPELAAEFKRRMAKELPANWKEATNAIIAETNEAAASVASRKASQNVIAALAPVLPEFLGGSADLTGSNLTSCADFKHVSGKEPGNYISYGVREFGMYAIMNGMALHGGLMPFGGTFHMFSDYAKSAFRMAALMKIRTIAVLTHDSIGQGEDGPTHQPIENTSAMRYIPNMDVWRPADSVEVAVAWTAAVERLDSPSSLVLSRQGIPGRKHDVADFSAMRKGAYVLSEAKGDTQVILIATGSEVDLAAKAQEALAAEGINARVVSMPSTNVFDRQDQAYKDSILIPGIKRVAIEAGVTDFWRKYVGLEGSVVGIDTFGESAPGGVLMEHFGFTVDNVVKTVKEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN49</accession>
    <name>A0A1D3RN49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase associated protein RapA</fullName>
            <ecNumber evidence="2">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00434_8</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016817">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022737">
        <property type="entry name" value="RapA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12137">
        <property type="entry name" value="RapA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="473" mass="53103" checksum="56EC736AC76737E7" modified="2016-11-30" version="1">MVGGKNKQLDGEQVLLICRQAETALKLQKSLREQYAVNAAAFHEGMSIIERDRAAAYFADEDAHVRILLCSEIGSEGRNFQFVHHLILLDLPENPDLLQQRIGRLDRIGQKQAIKIHVPYIVGSKQHSLCQWYDQGLGLFQANSNAASEVYRVQKGAVEQVCRSNDQKGLQELVASSKALIQKIEAEMHQSRDLLLEFNSCRKDIAAQLIGKIQSLSQPNVLWAYMEDIFEYFGVDSEYHSKTCAILQAGQAQRVTQFPYVPEDGVTVTVSRDVALAREDMQYLSWEHPMVASAMDLVVSDNIGSAALSVVKHKQLKPGQYLLECLFLIECSAPLTLQLNRFLPATPIRVLIDQAQKDLTEQIAHEELVELVHKFEVEQITAFIGSEHKNINTMIAHAEHSAEIAMQAVISQASTRMLKMSAEEIKRLEALAQVNLSIKPEEIERLKGRAIASHGYIRDAKLRLDAVRFIIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN51</accession>
    <name>A0A1D3RN51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_491388_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000538">
        <property type="protein sequence ID" value="SCN47135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4696" checksum="521F3161CFE46160" modified="2016-11-30" version="1">MGFKAFHSAQATISGIETAHMIRKGQLSEEKIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN58</accession>
    <name>A0A1D3RN58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_14960_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000524">
        <property type="protein sequence ID" value="SCN47120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4576" checksum="BD69556055B2961A" modified="2016-11-30" version="1">MMKIGPNAPALDGLCIWMMQISSLYISHEEDFNFILISFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN86</accession>
    <name>A0A1D3RN86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00840_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000567">
        <property type="protein sequence ID" value="SCN47175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="111" mass="12747" checksum="1B0920E85C3DA97B" modified="2016-11-30" version="1">MNTEILANLFKALSEPIRLRILALLLEKGELCVCELVDTLNLSQSVTSRHLAYLRNNEIVTARREGVWMYYQLTDYALSELKPLFNFIQQSINNSKEIQTDLANVGKTRIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA4</accession>
    <name>A0A1D3RNA4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplE</name>
        <name evidence="9" type="ORF">BAZMOX_10545_5</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000565">
        <property type="protein sequence ID" value="SCN47171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="24"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="84"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="179" mass="20237" checksum="C866E9E9EB4D4011" modified="2016-11-30" version="1">MARLQEDYKEKILPALMEQFGYTSVMQAPKITKITLNMGLGEAVADKKVVQSAVNDMEKISGQKAVITLSRKSIAGFKIRDDMPIGCKVTLRQERMYEFLDRLISISIPRIRDFRGLSPKSFDGRGNFSMGVTEQIIFPEIDYDKIDTLRGLDICITTTAKTNEEGLALLKQFNFPFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB9</accession>
    <name>A0A1D3RNB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_57405_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000399">
        <property type="protein sequence ID" value="SCN46957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="5311" checksum="5683145BD458784B" modified="2016-11-30" version="1">MGDYTVYYIDFILLFVLIRRFKKGNLFFHWQSLNDIFNCDDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC4</accession>
    <name>A0A1D3RNC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_33332_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000573">
        <property type="protein sequence ID" value="SCN47190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="236" mass="26149" checksum="F62EAF5A5D81C9A8" modified="2016-11-30" version="1">MESERDTNESNGTKSLPLNKKTSKTTVESNQNGHGENTNDKDGSTLSANGNQSESTSCDKSQSEVACSSNSLHENTENVKIKEEPCDRTDVLGLTKKIFSSFPIKFGSLGSEREESADDSMENETQKELVDDNETNVCMYLSEEKQLFHAKLANNEKNDTNNHPNTKSVFITNGVEYHIRPVEDEQTSKLVFEYLELVNKEPKGIFSIDISGSLLKNEDDSVHGIDTSSSKVNSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE4</accession>
    <name>A0A1D3RNE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cysteine desulfurase</fullName>
            <ecNumber evidence="5">2.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_10865_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000426">
        <property type="protein sequence ID" value="SCN46987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="4">
        <location>
            <begin position="2"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="362" mass="39279" checksum="71C0E5DF7FE56EFD" modified="2016-11-30" version="1">MIYFDHNATTPIDERVLQAMLPFLTHFYGNPSSLYKLARLSRSAIDTAREQVAQLVHARPEQVIFTSGGTEANNLALKGTQHNTKLLTSAFEHPSILESERTERVSINSQGYIDQLDLQVKLNQVFDLASFMLVNNETGVVQDIASLSSLVKGKGHLMHTDAVQAAGKIPVDFQALGVDLMSISSHKIYGPKGCGALIGALEHITKPLLTGGGQESGLRSGTENVAAIVGFGKAAELAYLELEKRQAHCLQLRLYLEQQLLELPGLCIFAPASQRIANTVQFGIEHCIGEMVLMQLDKKNIAVSSGSACASNEPAVSHVLSAMGIEKSIAQSAIRVSLGKDNTQQEIDTFVQILKHIIKQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE9</accession>
    <name>A0A1D3RNE9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoserine phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01012_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.3.3" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000580">
        <property type="protein sequence ID" value="SCN47202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006385">
        <property type="entry name" value="HAD_hydro_SerB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01490">
        <property type="entry name" value="HAD-SF-IB-hyp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="219" mass="25436" checksum="D5A4549EDBC2A9BE" modified="2016-11-30" version="1">MSLAIFDLDNTLLADDSDYLWGQFLVDQGIVDSSYYEQENNRFYKEYKEGNLDIYEFLKFSLKPLSDNPLQDLLKWRSQFIEEVIRPILLKPAQELINKHQQQGDILLVITATNKFVTEPIVELYGINHLLATTPEFLGERYTGNVAGTPCFQEGKITRLNEWLQVTGYSLDDSWFYSDSHNDLPLLQLVEHPVAVNPDEKLKQYAEKSNWPIISLRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG1</accession>
    <name>A0A1D3RNG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_34121_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000500">
        <property type="protein sequence ID" value="SCN47089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="115" mass="13003" checksum="267FEA5ED734CDF0" modified="2016-11-30" version="1">MTTNKIPTTTVHQARLQVFQPTRLPKDCVREIETSWGIAKIDGKLGQVHADIVEAIFYYADRSKKFDDGRVVITVDHYKIKTSVGGGKCYSYPTINKRLDEIMKALIKLEIFATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI0</accession>
    <name>A0A1D3RNI0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name evidence="4" type="ORF">BAZMOX_50229_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000519">
        <property type="protein sequence ID" value="SCN47109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="123"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="331" mass="38133" checksum="690F3E87E0CB1C23" modified="2016-11-30" version="1">MSKIVVSALYKFATLEDFTELKKPLLQLMEDHQVKGTLLLAKEGINGTIAGDRAGIDAVLHWLRSDLRLADLESKESYELKMPFYRTKVKLKKEIVTMGVENIDPKKIVGTYVKPQDWNALISDPDVILIDTRNDYEVQIGGFKNAVNPATETFREFPQYVKENLDPSKHKKVAMYCTGGIRCEKSTAYLKEQGFEDVYHLQGGVLKYLEEVPVEKSLWEGECFVFDNRVAVNHSLEKGQYDQCYACRYPITEQDKQSVHYQKGVSCPHCYHKANELQRQRFQEREKQVQLAKQRGEEHIGSAARQASAERRALKQQDKAQQREKVRKREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI3</accession>
    <name>A0A1D3RNI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ORF">BAZMOX_02505_3</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="FMJP01000631">
        <property type="protein sequence ID" value="SCN47275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="102"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="143"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="173"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="255"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="364" mass="39778" checksum="867F42D7B85DF76D" modified="2016-11-30" version="1">MIIGILGAGQLARMLALAGKPLGLKFIFLDPTPESCAADLGKHLIGDYTDKALLAQFAAEADIITYEFENVPMEIIHFLAESTPVYPPEKALAVSQDRMTEKQFCRNLGIPTAAFAAVSSLADLEQAMSSIGYPAILKTRRFGYDGKGQVVLRKAQDLANAWDAVQNAPCVVESFVPFDREVSIIASRSVSGHTVYYPLSENTHEKGILRLAKNTLRDPLQAQAEQMINTLLTALDYVGTIALELFAVDDHLIVNEFAPRVHNSGHWTIEGSETSQFENHLRAIIDWPLGATNSIGYAAMQNFIGGVPSSDKLLSLSQVHLHLYDKAARKGRKIAHATARTDSLENFTDLIALLTKLAKQSDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL9</accession>
    <name>A0A1D3RNL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-polyprenyl-4-hydroxybenzoate carboxy-lyase</fullName>
            <ecNumber evidence="4">4.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_02505_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000631">
        <property type="protein sequence ID" value="SCN47272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008694">
        <property type="term" value="F:3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01636">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023677">
        <property type="entry name" value="UbiD_bacteria"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00148">
        <property type="entry name" value="TIGR00148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="487" mass="54453" checksum="CBF4F033549611D4" modified="2016-11-30" version="1">MKYKDLRDFIAQLEKKGELKRVTQEIDPVLEMTEICDRTLKQGGPALLFENPKGHNIPVLANLFGTPDRVAMGMGETSVTALRGVGELLSQLKEPEPPKGMKDAIDKIPVFKNVLNMAPKVVKNPPCQEIIRKGDEVDLGVYPIQTCWPEDVGPLITWPLVITKGPYKDRQNLGIYRLQVIAKNKVIMRWLAHRGGALDFKEWQDKNPGQPYPVSVALGADPATILAAVTPVPDSLSEYAFAGLLRGSKTEVAKSITNDLQVPASAEIVFEGFIYPDEMAPEGPFGDHTGYYNEVGEFPVFTIECITQRQAPIYHSTYTGKPPDEPAVLGVALNEVFVPILQKQFPEITDFYLPPEGCSYRMAVISMKKQYAGHAKRVMLGTWSYLRQFMYTKFVIVVDDDVDVHNWQEVIWAITTRMDPARDLTILENTPIDYLDFASPVSGLGSKVGFDATNKWPGETTREWGRTITMTDDVVKKVDEMWDSLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM7</accession>
    <name>A0A1D3RNM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MutT/NUDIX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02505_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000631">
        <property type="protein sequence ID" value="SCN47273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="156" mass="17309" checksum="16A4334F82B964CC" modified="2016-11-30" version="1">MDQLQSGIRITVRAVIIQEGKILLIKKNSPTDGIRYTLPGGALNAGETLHQAVIRECIEEINTPVVAHDVLHIADLFIPKLDPQPYTRHQLEILIDCQVPDSYTPNTGPEPDKHQVSVEWLVLQELPDYSISPDFFAALLINLHSGEHDVYVGSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN9</accession>
    <name>A0A1D3RNN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_08714_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000645">
        <property type="protein sequence ID" value="SCN47301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4571" checksum="22A42C34F4FDAC60" modified="2016-11-30" version="1">MSRIIKLLNVLALSGSVARIGESEERLVFRHNYPAKATNCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ0</accession>
    <name>A0A1D3RNQ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_79136_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000656">
        <property type="protein sequence ID" value="SCN47311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4389" checksum="4B06D1DE9F9EFF05" modified="2016-11-30" version="1">MRTAIAAHFGLANFPVAYCGLKIITSLALRFPDFQRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR0</accession>
    <name>A0A1D3RNR0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purE</name>
        <name evidence="7" type="ORF">BAZMOX_02505_4</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="FMJP01000631">
        <property type="protein sequence ID" value="SCN47276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="8"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="169" mass="17549" checksum="CCA143666319E923" modified="2016-11-30" version="1">MQEQLMTALVGIIMGSTSDWETMSFAAEKLELLGIPFEVEVVSAHRTPDKLFSYAESAEDKGLEVIIAGAGGAAHLPGMVAAKTIVPVLGVPVQSKALNGMDSLLSIVQMPAGIPVGTLAIGKAGATNAALLAAAIIANKHNEYKAPLNAFRQAQTEAVLANSDPRELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR3</accession>
    <name>A0A1D3RNR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_85627_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000633">
        <property type="protein sequence ID" value="SCN47284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018777">
        <property type="entry name" value="Replication_initiator_prot_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10134">
        <property type="entry name" value="RPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="300" mass="34751" checksum="D96527306ABCDD11" modified="2016-11-30" version="1">MLARRLKSLSRNYRKPPKDDKQLDIFEPPPLTDVATKDDISLMDVAVFGLGRKPRFEPIEYNLKDARIVVSGSSKYGMATIFDYDIFLYMVSFLTHEMNKVREEIKKGNDNYLPPRKIKPSVAELLKYCRRDHGGENYRLLEKSLERLSTTKISIKKESSRTRRAGMFSLIGDYTINTQKETGKITDITIAIPEWVYDGIVRADNPTVLTMNPDYFLLDKGTHRFLHRLARKAAGKGEAVYSLEKIYERCGTTREFRRWKADIKSTISMLDINPLPDYSITWEEKGKKINIRMVYTGKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU2</accession>
    <name>A0A1D3RNU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_10702_4</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000679">
        <property type="protein sequence ID" value="SCN47342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="107" mass="11565" checksum="5079393D99272243" modified="2016-11-30" version="1">MGLPDPRAQGSGNPGATNVMRIGGKKAAGITLFGDMLKGLIPVLIAQALNVGPLILSAVVFAAFVGHLYPVFFRFQRRQGGCDFIWRIFWGSLDAWWGGRGNLVYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW9</accession>
    <name>A0A1D3RNW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional acetyl transferase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_106008_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000579">
        <property type="protein sequence ID" value="SCN47198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20292">
        <property type="entry name" value="cupin_QdtA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008894">
        <property type="entry name" value="QdtA_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05523">
        <property type="entry name" value="FdtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FdtA" evidence="3">
        <location>
            <begin position="117"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="251" mass="27397" checksum="8942DC9A3FEA549C" modified="2016-11-30" version="1">MTGAYVGDGASIESDVILGPNSVVLGQSDHNKPMTRIMVGAVIGANATILSGVTIGTNARVEPGTVVTCSVPPYAIVEGNPAYISDYVEAHEAVGILDQKTHGVGINPKKQETRVNGVTLHQFRMVPDMRGNLSVGEFEKEIPFSPKRYFLVFGVPSAETRGEHAHIQCEQFCVAVKGSVSVVADDGVTREEFVLNQPHMGLYLPPMTWGIQYRYTPDAVLLVFASHYYDNNDYIRDYSDFQVLVKQSSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ7</accession>
    <name>A0A1D3RNZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease of the major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_00840_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000567">
        <property type="protein sequence ID" value="SCN47177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="7"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="399" mass="43502" checksum="DD742E70BAAA8C85" modified="2016-11-30" version="1">MNTPIRQYMVVTASYWAFTLTDGALRMLVILYFHQLGYSPFEVASLFLLYEFCGVITNLIGGWLAAHMGLNTSMHFGLALQIIALCMLLVEPSLLSVVYVMVAQAISGIAKDLNKMSAKSSIKLLVPNDAQGKLYQWVALLTGSKNTLKGIGSFLGATLLTSLGFRAAIAIMAGCLVIILILSFLLLQKDLGKTKYKPKFTDIFSKSPAVNQLSAARFFLFGARDIWFVIALPVYLQEHLHWNYTEVGTLLAAWVIGYGFVQSASPLITGIRRGKIPDGKTAMLWAILLAIMPLAIAGFLQQGWQADSVLIIGLLAFGTVFAVNSAVHSYLIVAYAKEDGVSLDVGFYYMANALGRLVGTLLSGWVYQSSGLISCLIVSAIFIMLTSLLSIALPRHRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP15</accession>
    <name>A0A1D3RP15_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaJ</name>
        <name evidence="10" type="ORF">BAZMOX_04778_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000741">
        <property type="protein sequence ID" value="SCN47423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="135"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="148"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="165"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="187"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="201"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="135"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="359" mass="38376" checksum="3631C97433371779" modified="2016-11-30" version="1">MAKEDFYKILGVERNASEAEIKKSYRKMAMKFHPDRNKDKPEGAEIQFKLVKEAYEILSDAQKRSAYDQFGHAGVDGSRGGGFGGGGAEGFGDIFGDVFGDIFGGGGGGRQRSSVQRGADLRYNLELTLEEAVAGTEAKIRVPVLATCSECSGTGAKKGSSPVTCTTCQGHGQVRMQQGFFSVQQTCPTCQGAGQQIKDPCRKCHGQGRIQENKTLSVKVPEGVDTGDRIRLGGEGEAGAQGGPSGDLYVQIQVKDHPIFTRDGANLYCEVPISIPVACLGGELEVPTLTGKVKLKIPAETQTGKLFRLRGKGVKPVRGGAVGDLMCRVQIETPVKLTKEQTALLEQFRDSLTGGWQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP49</accession>
    <name>A0A1D3RP49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_140607_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000662">
        <property type="protein sequence ID" value="SCN47319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009744">
        <property type="entry name" value="VirC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07015">
        <property type="entry name" value="VirC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="236" mass="25387" checksum="84251D6DC9521EC8" modified="2016-11-30" version="1">MTTIVFASSKGGAGKTTAAVVMAGELARLGQSKNIKITLIDADPNQHSAEWALKDGCPSNIILKSSSEETLLDDIERAGEQGGFVVVDLEGTANIGVTHAIHCADLVILPCQGSHFDAKEIVKTIRLIKSQSKIARRDIPFSILMTRTNPAIQPRGLKDILSQFDQAGFDLFKCSLIEREAFRAIISFGGLVNDLDKKQVSGTEKAAANALAYAAEAINKIKANNQEEEKRSVKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC0</accession>
    <name>A0A1D3RPC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_364405_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000683">
        <property type="protein sequence ID" value="SCN47348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="52" mass="6114" checksum="96ACCDE84021AC1D" modified="2016-11-30" version="1">MVNIDQTEVDRLSTLEQVKSIEEDMLMTPDVMEKTLNSKRAKKKMAKKKHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC9</accession>
    <name>A0A1D3RPC9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="2">L11 Mtase</shortName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prmA</name>
        <name evidence="3" type="ORF">BAZMOX_01131_4</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000799">
        <property type="protein sequence ID" value="SCN47514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00406">
        <property type="entry name" value="prmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="292" mass="31939" checksum="03DE1253B46348CD" modified="2016-11-30" version="1">MAWHQISVVSKAALSSDISDSFSELGAVSVTYMSATSQPIYEPNIGETKIWEHTKTIALFELDASPDLIKTLLFEQYPDDSMQDWQAEVLEDQVWERSWMEHYKPMRFGDHLWVYPTGQEQFLPGTVSLILDPGLAFGTGTHPTTALCLEWLAKHDVTGKTVIDFGCGSGILAVAAILLGAQEAHAIDIDAQALTATLDNAKKNNVSSKIKTYLPEDFSVFTADIVLANILAKPLIELSPAISALVRPQGELVLSGILKEQASSVSNAYQANFTINAPTIQGDWCRLDGIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF7</accession>
    <name>A0A1D3RPF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_66863_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000668">
        <property type="protein sequence ID" value="SCN47327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4682" checksum="521F3161CBB56160" modified="2016-11-30" version="1">MGFKAFHSAQATISGIETAHMIRKGQLSEENIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF8</accession>
    <name>A0A1D3RPF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
            <shortName evidence="4">PRAI</shortName>
            <ecNumber evidence="2 4">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trpF</name>
        <name evidence="6" type="ORF">BAZMOX_108156_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TrpF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.24" evidence="2 4"/>
    <dbReference type="EMBL" id="FMJP01000838">
        <property type="protein sequence ID" value="SCN47581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044643">
        <property type="entry name" value="TrpF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894">
        <property type="entry name" value="PTHR42894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PRAI" evidence="5">
        <location>
            <begin position="6"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="210" mass="22873" checksum="DD65DC59B0606714" modified="2016-11-30" version="1">MTRTRVKICGFTDVEQAAHAAYAGADAIGLVFFPPSSRNVSINKAQEIVAALPPFTSVVALFVDATEKKIREVLKHVPIDLLQFHGNESASACRLYTKPYMKAIRMQSDTNISTLSTQYHDAAGLLLDAFHADAQGGTGQQFDWDLIPKDNTIPIILAGGLDEYNVGEAIARVKPYALDVSSGVEVTKGIKDNNKISAFLNEVYQSDRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH3</accession>
    <name>A0A1D3RPH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-bound lytic murein transglycosylase B</fullName>
            <ecNumber evidence="4">3.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_03760_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.2.1.-" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000816">
        <property type="protein sequence ID" value="SCN47546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011757">
        <property type="entry name" value="Lytic_transglycosylase_MltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043426">
        <property type="entry name" value="MltB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031304">
        <property type="entry name" value="SLT_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163">
        <property type="entry name" value="PTHR30163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30163:SF0">
        <property type="entry name" value="PTHR30163:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13406">
        <property type="entry name" value="SLT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02282">
        <property type="entry name" value="MltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920255" evidence="2">
        <location>
            <begin position="23"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="SLT_2" evidence="3">
        <location>
            <begin position="29"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="330" mass="37371" checksum="F16B5D2EA0164977" modified="2016-11-30" version="1">MHKLLIASLIFLSTVISPLAQAEIDDQVAVQKFTGKMVDQHQFAADALAKLFKSVEIKPNIIAAMTRPAEGMPWYKYRKIFMRDSRIQGGVKFWQANQASLKLTAQRYGVPEEIIVAIIGVETLYGERTGGHRVIDALATLAFDYPKRSKFFLSELEQFLLLCREEKINPLEPIGSYAGAMGMPQFMPSSYRHYAVDFEGDMKRDIWHNPADTIASVANYFAKHHWQTGQDIAFVVQANGDKYKQALTKGLSPNMTVKQLQNLGVQVPKQVAAQERVRLLSFEQEYGDDLWIGLNNFYVITRYNHSPLYAMAVFQLSAAIKQQYRLASHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM8</accession>
    <name>A0A1D3RPM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="6">FHS</shortName>
            <shortName evidence="6">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhs</name>
        <name evidence="7" type="ORF">BAZMOX_00536_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000767">
        <property type="protein sequence ID" value="SCN47458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="557" mass="59762" checksum="C0D34D020178C8BC" modified="2016-11-30" version="1">MSDIEIAQKAKMQPIIKLAAEKFNIPAEHLDPYGHYKVKISLEYVNSLKDQQDGKLILVTAISPTPAGEGKTTTTVGLGDAMNRIGKKTIMCLREPSLGPCFGMKGGAAGGGYSQVVPMEDINLHFTGDFHAIGVAHNLLSAMIDNHINHGNKLGIDSRRIKWKRVVDMNDRALRQITVGQGGPANGYCREDGYDIVVASEVMAILCLATNRADLKERLGRIVIAYKTDKITPVYARDLNAQGAMAALLKDAIKPNLVQTLENNLAIIHGGPFANIAHGCNTVTATKTALKLADYAITEAGFGADLGAEKFIDIKCRMAGLKPSAVVLVATARAIKSHGGVKKDELNNENLAAIESGFANLERHLHNITEHYGLPCVVCINHFTFDTEAEVALIIKKCEALGAKCIVSKHWAEGGAGAEALAQEVVNIVDNREPGCRFVYDESLPLWDKIETISTKLHGAAKVTASPKVKAEVKVLQAKYGHFPICMAKTQMSFSTDPTAIGAPSDHTVEITEVRLANGAGFIVAIAGNMMTMPGLPKVPAAERIDITDEGVITGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP8</accession>
    <name>A0A1D3RPP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02140_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000854">
        <property type="protein sequence ID" value="SCN47602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="109" mass="12513" checksum="4D6FEA018288F9FF" modified="2016-11-30" version="1">MTDLPEKTCSIERLVTHPKLVEAALSGRKTQQRRDGVYAYPNETFTLEGQKFIVTDLTRETIGDMTDAEAQAEGYPSLAMYRDLILRMHAGMEWDESAPVWVHHFKRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP9</accession>
    <name>A0A1D3RPP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_23642_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000914">
        <property type="protein sequence ID" value="SCN47673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0533">Nickel</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="10582" checksum="D33CDF8A73BAEDB9" modified="2016-11-30" version="1">MFSLLLLGFLIGMRHALEADHVAAVASLASKTTSVQSAIKQGAVWGLGHSFTLFLFSSIIILSESIIPKNPSYGARIFCWYYACYPRCRCHQKISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR7</accession>
    <name>A0A1D3RPR7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00594_8</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="306" mass="33740" checksum="FA2F82085DF52809" modified="2016-11-30" version="1">MLGSAPLEILDIFPYLKKMVSLEGSDLFITSGSPVKTKIHGSAVELDSYLLTPELTKSVAYAIMTQEQIEEFEQTKDLDFAISLPDKSARFRVNAFYQRGTIGIVLRLIPAIIPTAKELDLPEILTELIMAKRGLLLMVGGTGSGKSTSLAAMINHRNINAAGHILTIEDPVEFSHPNLKSIVNQREVGVDTASYARALKASLREAPDVILIGEIRDRETMEAALELANTGHLCISTLHANNANQAMERIINMFPHVQHKQLFMDLAINLNAVISQRLIPDVRGKRCAAIEVLINTPHISNLIFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS0</accession>
    <name>A0A1D3RPS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_54488_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000896">
        <property type="protein sequence ID" value="SCN47654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5173" checksum="FFC1D79164D64AEF" modified="2016-11-30" version="1">MNDVIDTVLTDAILGLFNYQHNHMLIQVEMQIVFQKGASRRKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS7</accession>
    <name>A0A1D3RPS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Suppressor of inhibitory function of ChpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_40515_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000927">
        <property type="protein sequence ID" value="SCN47691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9683" checksum="236D99A928F639F7" modified="2016-11-30" version="1">MQTLVRKIGNSTGMIIPANILKKYSLNIGDKLDIQDDNGRIVIAPTKTKHKYTLTQLLDKCDETVLMPQELIDWDNTPEVGNEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS8</accession>
    <name>A0A1D3RPS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.60</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_320749_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.7.60" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000931">
        <property type="protein sequence ID" value="SCN47703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4948" checksum="EA2BB2A4A3161433" modified="2016-11-30" version="1">MTDDASALELQGKQPKMIAGRADNLKITRPEDLALAQFYLEQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT4</accession>
    <name>A0A1D3RPT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stringent starvation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_32578_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000937">
        <property type="protein sequence ID" value="SCN47710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="72"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="193" mass="22007" checksum="09B37C569B446A83" modified="2016-11-30" version="1">MSHCARLALHEKGVTAEIEYFDPTDPPESLLELNPNGTSPTLVERDLVLYDSRIIMEYLDERFPHPPLHQMDPVSRANARMVIKRIDQDWYHLLGEVLNSGEKKSARAKKMLREGLVAAVPLFAANEFFMSEDFSLIDCSLAPLLWRLPSIGIELPENAQIINQYAQKLFSREAFAESLSEEEHEMAKLPSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU4</accession>
    <name>A0A1D3RPU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_62777_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000946">
        <property type="protein sequence ID" value="SCN47723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4775" checksum="492C62EB5DF9C142" modified="2016-11-30" version="1">MTIMRLSELKLAMGTVAISMLMARAGGLEFVLTMKARQNYGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW8</accession>
    <name>A0A1D3RPW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sulfite reductase [NADPH] flavoprotein alpha-component</fullName>
            <ecNumber evidence="13">1.8.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BAZMOX_10997_1</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="10">Binds 1 FMN per subunit.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="13"/>
    <dbReference type="EMBL" id="FMJP01000906">
        <property type="protein sequence ID" value="SCN47662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010199">
        <property type="entry name" value="CysJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000207">
        <property type="entry name" value="SiR-FP_CysJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 10" id="KW-0288">FMN</keyword>
    <keyword evidence="6 10" id="KW-0521">NADP</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="11">
        <location>
            <begin position="26"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="190"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="32"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="79"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="345"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="363"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="378"/>
            <end position="381"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="478"/>
            <end position="479"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="484"/>
            <end position="488"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="520"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000207-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="558" mass="61686" checksum="BA0C104AF0AE8A19" modified="2016-11-30" version="1">MGFFAGMHSHILQSAGSGDAANARTITILYGSQTGNSESVANDAAQAAKAHGLNAKVLGMDEIERDAFIGLEYLLIITSTYGEGDMPDNAQMLWEAISSDDSISLANMKYSVLALGDTSYDLFCQAGIDWDQCLAKLGATCLVERIDCDVDFDEAAESWIGSIIPLMSNGAATMTIDSNNTAKAATYGRKKPFPGKLVANRLLTSPDSSKEIRHYEISIAGSGLSYEAGDALNVVPTNCPKLVADIIKAIGCTGDEEEPVHGELMRLSEALREHYEIKLPNKELLDEIAKRSGDQELNSVLASGDKDQLAKYLWGRDTLDLLLPFPNMQFSAAEFLALLKPLQHRAYSISSSGKAHPETVHLTISSVRYRSFGREHKGVCSTYLADLADENTPIRCFFSPNKVFRVPEDNDAPMIMVGPGTGIAPFRAFLQEREFRQAKGINWLFFGDRNAATDYIYQDEIEAMQNSKLLTKLDLAFSRDQEEKIYVQDRMREKGAELFALLEQGGYFFVCGDAYRMAKDVDKALHDIIAIHGNKSAEQAIEYVNQMKKDKRYVRDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ04</accession>
    <name>A0A1D3RQ04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_122810_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000993">
        <property type="protein sequence ID" value="SCN47783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="53" mass="6313" checksum="E9B0F22406D2D6EA" modified="2016-11-30" version="1">MEERGVNVDHATLNRWVIRYAPTIAAKAHSQKRNTNRSWRMDETYIKVKGKWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ26</accession>
    <name>A0A1D3RQ26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_05068_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000978">
        <property type="protein sequence ID" value="SCN47764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="201" mass="23703" checksum="634CE7192C61DA01" modified="2016-11-30" version="1">MSIQKEIILRYKSSGHVRFQIPERLCSPEIATFVSDAISQIDGVYQVNLYRNKKKLAIRFTNETLSFKDLTQQLLTLFTDLEHKNFFVAKASPTKTAFIKNIFSDWQGARWAKGKYTETKETAQAIGILAKVGLKKKPEILINPEKTLINFFNDVLILFLIKTHWKLITKKWLLEPLKYRYQWLTVFYLMYLFIRSKNKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ32</accession>
    <name>A0A1D3RQ32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_22098_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001009">
        <property type="protein sequence ID" value="SCN47801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="238" mass="22681" checksum="756CA148BA06D931" modified="2016-11-30" version="1">MAPPEPPPAEAPADADADADADADALAAAAAWRLAKILAMSFDRRDAESPPAEAPAAAPAPTAAALRDAAAAAAAAAAAEDEEPPPIVPPAAAADAAAEADAAPPNPPTPPNLTTLPALPTPPAPNPAAAAAAAAAAALAPALAPALAPALAPALAPAPALAPAPPNPSKLSAANPPSISNKSRPPTLSKSSSSANSRSNSPPNPNPNPLPPPPALPPAPPPRAANNSSNSKSPPNPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ60</accession>
    <name>A0A1D3RQ60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-succinyl-L,L-diaminopimelate desuccinylase</fullName>
            <ecNumber evidence="2">3.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00742_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000881">
        <property type="protein sequence ID" value="SCN47628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="76"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="211" mass="23162" checksum="A5D3AA98D0FE7EF3" modified="2016-11-30" version="1">MKGGIACFVTAVERFIAQYPEHNGTLAMMITSDEEGPATNGVVKVVEVLEQRNEKIDWCLVGEPSSDKKIADVIRVGRRGSLCAKLQVKGIQGHVAYPEIASNPIHSFAPALKALTDEVWDKGNDFFPPTSLQVSNINSGTGAENIIPGELELQFNLRFCTELDEASIKQRVHAIFDQFDFDYDITWRLSGNPFLTEGGALIEATHAAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ70</accession>
    <name>A0A1D3RQ70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_18015_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000887">
        <property type="protein sequence ID" value="SCN47638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5430" checksum="F6AF39059EE94D5C" modified="2016-11-30" version="1">MRDIRNRIVHDYVPEKIAEIYQLIRGEFYNELRQLDQKLKKIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ71</accession>
    <name>A0A1D3RQ71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="8">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purC</name>
        <name evidence="10" type="ORF">BAZMOX_02007_2</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01001073">
        <property type="protein sequence ID" value="SCN47895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="9">
        <location>
            <begin position="19"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="297" mass="32952" checksum="9D53E619CFAA1BA7" modified="2016-11-30" version="1">MTAPAALFESSISNLKLHTRGKVRDIYEVDEHHLLIVTTDRLSAFDVILPDPIPGKGQVLTSVSNFWFKKVQDIIPNHLSDLSLKDVVPDADERAQIEGRAIIVKKLAPLPVEAIVRGYLIGSGWKDYQKTGSVCGIKLPEDLQLAQQLPEAIYTPSTKAVVGDHDENISFAETIPLLGEEIATKVRDISLRLYSTAAAYAQERGIIIADTKFEFGLDNTGKLYLIDEALTPDSSRFWPVEQYQVGISPPSFDKQFIRDYLETLDWDKTAPGPKLPDEVTAISSQKYQEAALKLTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ72</accession>
    <name>A0A1D3RQ72_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="13">ACCase subunit beta</shortName>
            <shortName evidence="13">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="13">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">accD</name>
        <name evidence="15" type="ORF">BAZMOX_01607_3</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12 13">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AccD/PCCB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="13"/>
    <dbReference type="EMBL" id="FMJP01001034">
        <property type="protein sequence ID" value="SCN47850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01395">
        <property type="entry name" value="AcetylCoA_CT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041010">
        <property type="entry name" value="Znf-ACC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17848">
        <property type="entry name" value="zf-ACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00515">
        <property type="entry name" value="accD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="15" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="14">
        <location>
            <begin position="27"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN47850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="287" mass="31784" checksum="00DB7AC836B74677" modified="2016-11-30" version="1">MSWFEKLVPSTIKRNSDSKKIAVPEGLWNKCSSCNAILYNTELEKNFNVCPKCDYHMRISARRRLDLFLDPDNREEIGVNLKPVDPLKFKDSKKYKDRISQAQKKTKENDALIVMSGTLKSDPVVVAAFEFGFMGGSMGSVVGEKFVRGINKSLELGVPFIVFTASGGARMQESLFSLFQMTKTSAALTKLAKAGIPYISFMTDPTMGGVSASLAMLGDINVAEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLQEHGAIDMIIDRREMRDEINSILAILTANKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ97</accession>
    <name>A0A1D3RQ97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HigB toxin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_347436_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001050">
        <property type="protein sequence ID" value="SCN47873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007711">
        <property type="entry name" value="HigB-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05015">
        <property type="entry name" value="HigB-like_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="47" mass="5549" checksum="5903535BE916BA7E" modified="2016-11-30" version="1">MNLPGWRLHALKGDKTGLWSINVSGNWRIVFEFKDGHAYIVNYEDYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB2</accession>
    <name>A0A1D3RQB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxaloacetate decarboxylase alpha chain</fullName>
            <ecNumber evidence="4">4.1.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_08831_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.1.1.3" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01001024">
        <property type="protein sequence ID" value="SCN47836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005776">
        <property type="entry name" value="OadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01108">
        <property type="entry name" value="oadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="8"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="514"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="589" mass="63134" checksum="B5D4CA2AC00E1CE5" modified="2016-11-30" version="1">MTQTNKPLGITEVVLRDAHQSILATRLRIEDMLPICEKLDQIGYWSIESWGGATFDSCIRYLGEDPWERLRSLKAAMPNTPQQMLFRGQNILGYRHYADDVVDKFVERCAINGIDVFRIFDAMNDMRNIEHAVKAVLNTDAHAQGTISYTISPVHTTAKWVEQGKVIEDMGAHSICIKDMAGLLTPYDAFELVSQLKASVDIPVHLHCHATTGLSVGTLIKAIEAGVDNVDTAISSLSMTYGHSPTESIVASMAGQPRDTGLDLEKLEEVAAYFREVRLKYAEHEGSLKGVDGRILLAQVPGGMLTNMESQLKEQGAADKFDEVLKEIPRVREDLGFLPLVTPTSQIVGTQSVLNVMTGERYKSISKETAGVLKGEYGLTPAPVNAELQARVLEGADVITCRPADLIEPEMANLTAELEAKAKAEGVTLADNIEEDVLISALFAQVGWKFIANRGNPDVFEPAPNPEAFAATKAAKSASSVESYTVNVDGKNFNVAVGPGGANLAISDAPQVTSDAVASSGAGVDSPLAGNILKINVSVGSAVAEGDVVLIMEAMKMETEVRARVAGTVSSVNVKEGDAVAVGDILVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQH0</accession>
    <name>A0A1D3RQH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HigA protein (Antitoxin to HigB)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_347436_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001050">
        <property type="protein sequence ID" value="SCN47872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013430">
        <property type="entry name" value="Toxin_antidote_HigA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36924">
        <property type="entry name" value="PTHR36924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02607">
        <property type="entry name" value="antidote_HigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="28"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="97" mass="10938" checksum="B562A91F33E58686" modified="2016-11-30" version="1">MIEQHNPMHPGEFIKRVYLIPCHIGSNELARNLKVSDGLVSRLINGKTDVSPAMALKLSKVLGRSPESWLQMQDNFNLHQAKKELDLSEYEPLELAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQI3</accession>
    <name>A0A1D3RQI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3362 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_309186_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000933">
        <property type="protein sequence ID" value="SCN47707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024560">
        <property type="entry name" value="UPF0313_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11842">
        <property type="entry name" value="DUF3362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3362" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="56" mass="6508" checksum="0A44114E8A5B49E4" modified="2016-11-30" version="1">MGRANLIGNGKQHLVPNWQLKEGGKDDKIINKGKSFRTQRTENNQRRAPSRNHKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQI6</accession>
    <name>A0A1D3RQI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_506317_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001093">
        <property type="protein sequence ID" value="SCN47924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="47" mass="5533" checksum="CA4318B8B1460921" modified="2016-11-30" version="1">MDETYIKVKGKWVYLYRAVDSHGDTLDFMLSERRDEDAATAFFKQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQJ5</accession>
    <name>A0A1D3RQJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_18695_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001077">
        <property type="protein sequence ID" value="SCN47902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="719" mass="81023" checksum="3AD5DE0FA1F73B66" modified="2016-11-30" version="1">MFILQPLYGKLMLPLLGGSPAVWNTCMVFYQMLLFFGYLYAHFISTRYKPLRQVQVHGALILISLIALSVGLPEIMTPPTESNPTLWLVGVLFISIGLPFFILSTTSPLIQKWFSHVGHHTSHDPYYLYAASNSGSLLALLSYPFIIEPNIGLSAQKITWSVGYIGLILLIAACAWLFIRLYQGSSNTEINEQKVVQVEPTLLTKLHWLALAFVPSSLLLGLTNFVSTDIAAAPLLWIVPLTLYLLSFVLVFSRWAKGIHRESVWLQPVVLLPFIAYSFINPAILPYWVDLVLHLCAFFLAVMVCHGELAKYRPHTAYLTLYYLIMSFAGMLGGMLNTFVAPFIFNGIYEYPIMIVAALLLRPADKIWQNQQWQVWAKQAVFPLLIFVLGWAIYLGVSDLGGYMDNIGTALILLAGLTYAFRKQALSLALFTGTIIFFIVGLRAIMSNTIYQERTFFGVVSVRDSVLLNEQGRPEKYKELFHGTTKHGAQRSGIHEQEPLTYYSRPGPMGQLFKEFDNSNQQWQIGIVGLGAGALACYAKPQQIWTFYEIDPVIVDIAKNINYFTYLQRCTPKAAMVIGDARLSLQSEADAKFDLLVIDAFSSDSVPTHLLTQEAIQLYLSKLTENGILAFHITNRHLALKKVLSDHTKQLGYAALIQEFKPQREIPLVIATDWFVLAKNEQALAPLYKQGLGLWQKPALYFDMKPWTDDFANIVSIWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQM1</accession>
    <name>A0A1D3RQM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type I site-specific deoxyribonuclease</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_02029_2</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01001039">
        <property type="protein sequence ID" value="SCN47859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="353"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="723" mass="84218" checksum="05AFB6D0438CF520" modified="2016-11-30" version="1">MNELHLQDKFLVPFMRDGLGYREVKANTVSNSLIIEEDLEEFISSSTLNKNPYETLLKKYGDNRKKLLADLIELIQERSGFNRNMALFLNTNKSVTLQGIKLHLFYTGDSVIHDNGLFDQNIFSVVQELPYKYQYEGKQIFSFRPDLCFFVNGIYLGFSELKSNYNNQNARKNGRGKVIKDYFEAVKTYYEHIECNAILSEKDKEFYRRDFLKIFEKAIHITTTDIKDTYVIRTISDFFDEILETCRQGKFDREDYNKRVTKVFKPYPLLKPDADKKDKFKELFTVHYGKSFIEKEILYYNFIERDVKHVKGVKELKDEKGTLISPRPKQKFGTDKIMAKIDEFLEHEGEDDYFITLLEKQLSGVSTAKKQELIDKRKAYSNNKTVYSLLMQYAAGFGKSNIIGWSALQLKDMRRDGHYVYDKIMIVVDRLQLRSQIDSLMLNMNIDKRMYIEAHNKKTFQEALKSDTRIVIVNLQKFGAAREMLDKNVLKKLASLRIVFLIDEIHRSNSGAQHDEMLNVFDELQSAFDQDKSYKETRTKKNLIIGFTATPDDNALSRFGEYSGYAEGEKLWIPFDSYTMKEAIEDGFILNPLKNIVPVASKMLFNLPENELEGFTKKEYKDAQKKQIYEERERIDAVSKYVADLLVKDVYRQIRGTGKAMLAVHSIKSAIAYKQAVTKHFAELVKQPKYEKYAEAPIYIVYSDNQDEQSARGLNGGLSEEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQQ6</accession>
    <name>A0A1D3RQQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ORF">BAZMOX_17185_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="FMJP01001088">
        <property type="protein sequence ID" value="SCN47919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="40"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Orotate binding" evidence="4">
        <location>
            <begin position="34"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="124"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="213" mass="23515" checksum="337C7C8F6666DF7A" modified="2016-11-30" version="1">MLDYQKQFIQYSLECGVLKFGQFHLKSGRISPYFFNTGLFNTGAQLAKLGEFYAQALIHAKIKVDILYGPAYKGIPLVCTTSIAYAHRQDSDIPFAFNRKEVKDHGEGGNLVGAPLKGNVLILDDVITAGTSVRESVVIINDAGATPAGVLIALDRQEKGKNDISAIQEVSDRFDMPVVSIIALEHIIEFIENDDAYKINIETIKAYQQQYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQW0</accession>
    <name>A0A1D3RQW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_79250_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001046">
        <property type="protein sequence ID" value="SCN47867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="77" mass="8857" checksum="02171282E6E7ABF5" modified="2016-11-30" version="1">MAWEMGTTFNWKVLFLPVRGRGNVIGIAFAEGVDKFSLQALRKKAVLLEEQYQIEFPDFVKDLKRNNASILKRVINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQY8</accession>
    <name>A0A1D3RQY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alkyl hydroperoxide reductase subunit C-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_02007_4</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001073">
        <property type="protein sequence ID" value="SCN47897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="4">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="201" mass="21953" checksum="1A9154BD9A68FFB4" modified="2016-11-30" version="1">MSVLVGKQAPDFTVPAVLGNGEIVDSFSFSEATKGKYAVIVFYPLDFTFVCPSELIALDHRMDEFTSRGVEVIAVSIDSHFTHNAWRNTAINDGGIGPVRYTMAADIAHTIVKDYDVEAENPQVAYRGSFLIDKTGLVRHQVVNDLPLGRNTDEMLRMVDALQFHEEHGEVCPAGWTKGDAGMDATPAGVASYLSENSDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL36</accession>
    <name>A0A1D3RL36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_18013_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000002">
        <property type="protein sequence ID" value="SCN46391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021979">
        <property type="entry name" value="DUF3584"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12128">
        <property type="entry name" value="DUF3584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="214" mass="24950" checksum="9692D1DBD65A5643" modified="2016-11-30" version="1">MARLQGRLTSKVKTLGYWEQIVKFTDQYDEWSRHTDGQLPADDFAEIVRRIAEQLQSKNKVEMKLVNLLELEIIVTENGRSKRATHAEELRQISSHGLSYLILCVFFIALVNMIRKDQPVRFIWPMDELKELHQLNIEMLIELLTKNNITLLSAFPDPDPEILGFFKNRYQVHGFRELIEMDMDTEYMASLETLAFDVELPETKTDGIAESMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL44</accession>
    <name>A0A1D3RL44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_56643_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000037">
        <property type="protein sequence ID" value="SCN46435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="288"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="489" mass="54923" checksum="C308826570247D3E" modified="2016-11-30" version="1">MNKLKLALRFLRRDSRSGELTLLMLALIIAVASSTAISLFANRMNRTMNFQAAEFLAADMVVSSPELISAHYLQQAKNLNLKQSQTSEFSSMLIENEQFLLAGIKVVSDNYPLHGTLKVRQETYAQEQTLKHGPKQGEIWIEWRILSTLQLKLGDSLQVGELPLLVSHIITYEPDKRGDLYSLSPRVMINAADLAATKILQPGSHVHYFYQFAGAEAEIIKFKQWLKPQLTASQRLMDIYDDRPKIGSALQKAERYLGLSSIVVVLIAGVAIAMATRRFSERHFNSTAILRCLGYKQNEVLQLFLWQFLFIGLIASFIGCILGWISQALLFQLLRDLLPAQVADPSYLAILFGMIIGIVVLFGFALPPLLRLKQVSPLRILQRDLTPLPSSAWLVYGLAISLLVLLISQYTQDLKMTLSIIIVGMLSLAILGGLSYGLLGLTRLLLPHVNLTWRFGLQGLSKHQNSNITLNPSFQYYFASDYSQFYCTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL88</accession>
    <name>A0A1D3RL88_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="8">PCK</shortName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="4 8">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pckA</name>
        <name evidence="9" type="ORF">BAZMOX_10981_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 8"/>
    <dbReference type="EMBL" id="FMJP01000039">
        <property type="protein sequence ID" value="SCN46441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="231"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="526" mass="58196" checksum="FA5E405B25276D6A" modified="2016-11-30" version="1">MSGLSAESLGLKSIASIYHNLSHDELFEHELKNKEGKVASSGAMMVDTGIFTGRSPKDKYFVEQSPSKENISWGAVNKPISCEHFDEIYDDVIDYLSDKDLYVTDGYSGASVTSRKSVRFITEFAWQSHFVKNMFIPPKEDELENFAPDFRVYNASNMKNEKWQKHGLNSEVFVIFNIEKNVAIIGGTWYGGEMKKGIFTMMNYWLPLKGVLSMHCSANVGKEGDVALFFGLSGTGKTTLSTDSARELIGDDEHGWDDDGVFNFEGGCYAKTIDLSAENEPEIYGAIKHGALLENVVADDDGIVDFTDKSKTENTRVSYPIHHIENHRASLQAGMPRNIIFLSCDAFGVLPPVSKLTKEQAMYYFLSGYTAKVAGTERGITEPVTAFSACFGEAFLPLHPTVYAKLLGEKMEEHGVNAYLVNTGWVGGGYGVGNRMSIKGTRACINAILDGSINDSEFETVPFFQLHIPKTLGGVETSLLNPRNAWEDKESYDTTAEKLAGLFIKNFKKYTDSNNGFDFTKAGPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL94</accession>
    <name>A0A1D3RL94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_56643_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000037">
        <property type="protein sequence ID" value="SCN46436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="12"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="114" mass="12774" checksum="3CD79932A8EC9ACB" modified="2016-11-30" version="1">MLPLELIGDKQAKSLATQLLNRVGLSHRLNHIPNQLSGGEQQRVALARAFVTHPKILFADEPTGNLDSNTGEHIIDLLFELNKENQTTLVLVTHDQRLAYRCARTIELSRGRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLC5</accession>
    <name>A0A1D3RLC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YafQ toxin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_269516_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000098">
        <property type="protein sequence ID" value="SCN46515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004386">
        <property type="entry name" value="Toxin_YafQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40588">
        <property type="entry name" value="PTHR40588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15738">
        <property type="entry name" value="YafQ_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006156">
        <property type="entry name" value="YafQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006156-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="56" mass="6692" checksum="143B9D98594078B5" modified="2016-11-30" version="1">MTQETLPDFYLNHPLRGNWKGYRDVHIEPDWLLIYRVADDELQLTRTGSHSDIFCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLC6</accession>
    <name>A0A1D3RLC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_468717_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000064">
        <property type="protein sequence ID" value="SCN46470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4844" checksum="521F313E108C9835" modified="2016-11-30" version="1">MMGFKAFHSAQATIVGIETAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLD3</accession>
    <name>A0A1D3RLD3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Ferrochelatase</fullName>
            <ecNumber evidence="7 8">4.99.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Heme synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Protoheme ferro-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hemH</name>
        <name evidence="9" type="ORF">BAZMOX_15316_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>2 H(+) + heme b = Fe(2+) + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.99.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="7 8"/>
    <dbReference type="EMBL" id="FMJP01000053">
        <property type="protein sequence ID" value="SCN46454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="2 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="324" mass="37310" checksum="1282D33A879DEE73" modified="2016-11-30" version="1">MAQKKRGILIVNLGSPKHLTVRSVRRFLRKFLSDPRVVNLPRSLWWVILNFFILPFRPFKSKAAYAEVWTDRGSPLTFLTQDLTDKVSAHYQRNPHVTVAMAMSYGAPSLTAQLHKLQKAECEQVTIVPLYPQYSSTTTASVFDAVATELMQWRYIPELHFISDYHQHPLYISSIAGSIQHAWQNQPANELLLMSFHGLPDVLTKKGDPYYYQCIKTAELIAQKLNLQEDKWRVVFQSRFGKAKWLQPYCIETLMALPEEGFKNIDIICPGFVIDCLETLEEINMTNKAIFFEAGGEQYRYIPCLNDSDENVQLMVDLIENKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLE5</accession>
    <name>A0A1D3RLE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inosine-5'-monophosphate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.205</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04566_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.1.1.205" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000071">
        <property type="protein sequence ID" value="SCN46490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMPDH" evidence="1">
        <location>
            <begin position="3"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="60" mass="6501" checksum="8B467FD3549CD48A" modified="2016-11-30" version="1">MLAIIHQSIGGIRASMGYTGCATIEIMHDKAGFVRVTSAGMRESHVHDVTITKEAPNYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLG7</accession>
    <name>A0A1D3RLG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00699_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000100">
        <property type="protein sequence ID" value="SCN46521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="63" mass="7170" checksum="4DBD3FCF9E964F69" modified="2016-11-30" version="1">MIKAQYRHTGFTLLEVLIGMSIMSVMMLLLFASLRVCVQNWNAGEKKNCPSQPSRDCADFFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLH4</accession>
    <name>A0A1D3RLH4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FeoC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_324047_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000075">
        <property type="protein sequence ID" value="SCN46494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015102">
        <property type="entry name" value="Tscrpt_reg_HTH_FeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09012">
        <property type="entry name" value="FeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="75" mass="8570" checksum="880BC94EB200931C" modified="2016-11-30" version="1">MILSELRDYLKQQHRLSLLEMANHFDTNADALRGMLSKWVSKGKVKRIDMGASCGTSCCKCDPAMTEIYEWLDNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLH6</accession>
    <name>A0A1D3RLH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_249610_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000109">
        <property type="protein sequence ID" value="SCN46531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="64" mass="7091" checksum="794C545D48698131" modified="2016-11-30" version="1">MLSERRDEDAATAFFKQAINNNGLPDKVVMDKSGANYAGLANINLLLILARFATMIDICQVKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLJ2</accession>
    <name>A0A1D3RLJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">COG1548 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01476_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000038">
        <property type="protein sequence ID" value="SCN46439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002756">
        <property type="entry name" value="MfnF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03123">
        <property type="entry name" value="one_C_unchar_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="61"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="350" mass="38466" checksum="01C0FF47580B526E" modified="2016-11-30" version="1">MTNYRVGWDIGGAHLKAACLNQAGDVLAVYQEPCPLWQGLDTLEKALTAILARLPEKNLKHTVTMTGELVDLFVDRAQGVYDIIALMQQVLAQPSFAVYAGQLGFVAADAIEPKHIDAIASANWLASASYVAQKLKQGLFVDIGSTTTDILLLTKHQADAIGYTDFQRLTSSELVYTGLVRTAVMAVVQSVNFAGTEVGVMSEYFATMADVYRLTHELNELHDQNETADGGAKTELASARRLARMIGCDLQDFTLQDWQELAYAMREQQLTRIQIACQKQLQRMPDNMQTPLVGAGIGRFLVQEIAQRLGLKYIDFETLFTSPCKLTEMNIADCAPAVAVAYLAIEAKFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK3</accession>
    <name>A0A1D3RLK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_12008_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000116">
        <property type="protein sequence ID" value="SCN46542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="79" mass="8827" checksum="99251A65BE8D95D7" modified="2016-11-30" version="1">MAKIAPPTEKKAPVKRAVKKAIEMKSNKATGQTPPDAIIPLQIKIPETVKNEFKAMASIRGQSMNALFLEMFEEYKESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM3</accession>
    <name>A0A1D3RLM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_265722_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000132">
        <property type="protein sequence ID" value="SCN46562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4733" checksum="AA11D31052848829" modified="2016-11-30" version="1">MLDRLHYLDRKMMGFKAFHSAQATIAGIETVHMIRKGQLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ2</accession>
    <name>A0A1D3RLQ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmB</name>
        <name evidence="2" type="ORF">BAZMOX_02676_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000161">
        <property type="protein sequence ID" value="SCN46592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="208"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="229" mass="26384" checksum="68048E47B65F51E9" modified="2016-11-30" version="1">MSKEEVQNPPRIKSFIRRIGRMTGAQRNAVDTLWDKYCLNPEVVCDLPIIFGRSAPVILEIGFGNGESLAKVAEDNPDKDYIGIEVHKPGVGNLLAQLERKQISNVRIFYHDAIDVLEQCIPDVSLSGIHLFFPDPWHKRKHHKRRIVRPSFVKLIAQKIKPEGYFHAATDWQHYAEHMLKILAGAEYFVNASASQNYCSRPDYRPLTKFERRGLRLGHGVWDLIFKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW9</accession>
    <name>A0A1D3RLW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_328737_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000189">
        <property type="protein sequence ID" value="SCN46644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5038" checksum="5319E97513DF021C" modified="2016-11-30" version="1">MNAIASIPIGQQKRKPEPRAVKRRPKSYPLLKKPRNKAREAINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM08</accession>
    <name>A0A1D3RM08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative iron-sulfur cluster assembly scaffold protein for SUF system, SufE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_10024_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000213">
        <property type="protein sequence ID" value="SCN46684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="9"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="150" mass="16860" checksum="5B613FC271C78B14" modified="2016-11-30" version="1">MFDDLRDLYQEVIFDHNRNPRNFRVMEDADRKVEGFNPLCGDRLTLFLKMDGDKIIDASFQGSGCAISTASVSLMTEIVKGKTEAEAEDLFRQFHEMTTGKEDKIDLEAIGKLAVLAGVREYPARVKCATLAWHTLDAALKNEQEAISTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM17</accession>
    <name>A0A1D3RM17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_216531_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000232">
        <property type="protein sequence ID" value="SCN46712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="72" mass="8412" checksum="C9824E0C4F2437DF" modified="2016-11-30" version="1">MAVENKTIRTEAHRVAEKKYNKKRLKKPAIPAIRLENEEKTWTDEVFEKFGKSKKEAVLKGLELLKDSLNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM19</accession>
    <name>A0A1D3RM19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_246980_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000239">
        <property type="protein sequence ID" value="SCN46721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4273" checksum="256829AB16E8D8A1" modified="2016-11-30" version="1">MKARLFARVEPTHKSKIIEYLQGEGEVSAMVGLFCFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM20</accession>
    <name>A0A1D3RM20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_495786_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000177">
        <property type="protein sequence ID" value="SCN46619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4476" checksum="C2C404EC9EED661D" modified="2016-11-30" version="1">MPPSRTAIAAHFGLANFPVAYCGLKIITSLSLRFPDFQRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM44</accession>
    <name>A0A1D3RM44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_213116_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000266">
        <property type="protein sequence ID" value="SCN46761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920224" evidence="1">
        <location>
            <begin position="22"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="180" mass="19980" checksum="B9ECBE3EA14BF1DA" modified="2016-11-30" version="1">MKRLKLTVALLTTLAVTQSYAETVTMGHEVDIEYLSDRFDEPVLHVMDSIINYETGNGGLVVIKDKDGGVLCINNITGNKSSEVKFHDGQVYISGDVRGRAGWKETLYVGQMSNADTNPLLELTQYKNYDMDGDEIYTGNITYIGNVTYVGTDGSEMRDNLLEGTMNSVCKINVTTQRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM50</accession>
    <name>A0A1D3RM50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(FAD)-utilizing dehydrogenases</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_390087_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000245">
        <property type="protein sequence ID" value="SCN46726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="151" mass="16846" checksum="B4D5805F605A7B12" modified="2016-11-30" version="1">MALPCTISNARQSFTENLLFTHRGLSGPVVLQMSSYWHEGELINIDLLPAVDLQQALLTAQKDKTKVKLKNYLLQFFAKRLTPLFIANDLLECSLLDLSHKQIQLIAEQFHHWQIKPNGTEGYRTAEVTLGGVDCHCISSAENQGNGAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM67</accession>
    <name>A0A1D3RM67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_83415_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000129">
        <property type="protein sequence ID" value="SCN46557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="352" mass="38976" checksum="83656529EC3E31FD" modified="2016-11-30" version="1">MAIYAVWNNKGGVGKSYLSFQLASEYARQNPNKKVLVVDLCPQANASSMLLGGMVNGERNLTEIHTAQPRKTISGYIEDRVRSPYVSPNSGVGYITQVSQYNDRVPENLYLVVGDEQLEIQASRVTSATFPGPQDAWRIVHLWIRDLITDIQASWNDEETCVFIDCNPSFSIYTELALTAADRLLIPFSADGSSKRAVKAVLSLVYGVRRHQGDPQSDFFLESTRYRMAFPKIYMYIGNRLTQMNNSSASAFKTVVNEIGDEIWGVWQSSPQSFCTHPNGSPTPSNRRAFKLMFQYEVNDANTASVVSGALGIPIASITAGQKNISGKTVTVNQSQLDKQAPNIIDLVKNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM70</accession>
    <name>A0A1D3RM70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Particulate methane monooxygenase C-subunit</fullName>
            <ecNumber evidence="2">1.14.13.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00686_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.14.13.25" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000262">
        <property type="protein sequence ID" value="SCN46753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106317">
        <property type="term" value="F:methane monooxygenase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106318">
        <property type="term" value="F:methane monooxygenase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006980">
        <property type="entry name" value="NH3_CH4_mOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023349">
        <property type="entry name" value="NH3_CH4_mOase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04896">
        <property type="entry name" value="AmoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03078">
        <property type="entry name" value="CH4_NH3mon_ox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="250" mass="29089" checksum="02F549807F97AA7F" modified="2016-11-30" version="1">MAATTDSVKADASEAPLLNKVNLWAGLMLYLVFYSFIRWYEGVYGWSAGLDSFAPEFETYWMNMLYIELVLEVVIASTLWGYIWKTRDRKVMSITPREELRRHFTHWTWLVMYGWAIYWGASYFTEQDGTWHQTIVRDTDFTPSHIIEFYLSYPIYIITGVSAFLYAKTRLPAYQEGLSLMYMVSVIGPFMILPNVGLNEWGHTFWFMEELFVAPLHYGFVFFGWAALAIMGVVNTEVAALTKLLKKDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM85</accession>
    <name>A0A1D3RM85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c-type biogenesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_01705_3</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Possible subunit of a heme lyase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CcmH/CycL/Ccl2/NrfF family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000295">
        <property type="protein sequence ID" value="SCN46801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005616">
        <property type="entry name" value="CcmH/CycL/Ccl2/NrfF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038297">
        <property type="entry name" value="CcmH/CycL/NrfF/Ccl2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03918">
        <property type="entry name" value="CcmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011022383" description="Cytochrome c-type biogenesis protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="156" mass="18086" checksum="C7D2728A233DD260" modified="2016-11-30" version="1">MLRFFIIALLSITSVYAAIDTYEFKDKDKELRFHKLSADMRCPKCQNQNLADSNAAIATDLKQKIYLMLEADKSDVEIVDYMVERYGDFVLYEPRFNAQNAVLWLGPGVLLLLGLITIIWLTRRRDNKNDENSEQVPELDAKQQKQLQQVLNKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM95</accession>
    <name>A0A1D3RM95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c heme lyase subunit CcmH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01705_4</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000295">
        <property type="protein sequence ID" value="SCN46802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017560">
        <property type="entry name" value="Cyt_c_biogenesis_CcmI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03142">
        <property type="entry name" value="cytochro_ccmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="431" mass="46930" checksum="D97F269921291602" modified="2016-11-30" version="1">MSSLWMGFAVLLLIATLFLLLPLLKKRKTDEVAGSDVQQDNVLIFRDRLAELDAEKEQGTLEEEAYQALKAELEKSLLQDVAGKQQLEYKNQPLQVQQAVLIFGIVLVLMISSVAVYLHLGRSDDYADYLALKEQGETVQASGDASQKKAPDFATAVKMLKKKLAENPDDFDKYILLANSYAAMGQFKESADVYATLVKRIGPDNKDYAAAKGSYAQALFQAQGEQFTEEVNAAIEQALVADAQESTALILKGIQAYMQAEYAQAIEFWQQAKVKAGTMQTQRFIEPAIADARSKAGVPLAEAVAVVAKPTQPVANGAAQIIVNISLAPELQAKVSPEHTVFVFARAVGGRMPLAIERIQVKDLPKRIVLDDSKAAMPTATLSTVEQVDIIARVSLSGTPRPQAGDLFVQLDQVKVNAGKELNLVINQVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB2</accession>
    <name>A0A1D3RMB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_292994_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000291">
        <property type="protein sequence ID" value="SCN46794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5887" checksum="CF489FECDCD1735C" modified="2016-11-30" version="1">MCAFKADHDLFYAHWEIKGGLYQNLPINATAIPQLAYACDRTNKMSVQLWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB3</accession>
    <name>A0A1D3RMB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_276927_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000224">
        <property type="protein sequence ID" value="SCN46699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4047" checksum="F9DBD81440692244" modified="2016-11-30" version="1">MLLGRLPAPPCRLPSGFPGHPDPTFPCCTTGVRRPVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMH5</accession>
    <name>A0A1D3RMH5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD assembly factor SdhE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_179626_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SdhE FAD assembly factor family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000351">
        <property type="protein sequence ID" value="SCN46891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="SSF109910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="81" mass="9339" checksum="028A6A4209986393" modified="2016-11-30" version="1">MNLALKHLRWQCRRGTKELDAVLCCYLESCYMTANSSEQRLFLELLALEDDALLAYFFANSSPKTEGLKQLVDKIRSAFMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI5</accession>
    <name>A0A1D3RMI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative malonate transporter</fullName>
            <ecNumber evidence="8">2.7.7.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_03276_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the auxin efflux carrier (TC 2.A.69) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000342">
        <property type="protein sequence ID" value="SCN46873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="306" mass="33498" checksum="98B4B7BCC39D6D12" modified="2016-11-30" version="1">MFEQFLFALNVTAPILILLILGIVFRRTGFIDEHFISIANSFVFNITLPCMLFFSLATTPLSQSADIPLFLFGVLFTLISVLIFQLLSRFLIQQDKRGVFVQGAFRGNLGIIGIALAVNAYGSEILATASLYMALIAVIDNPLSVILLIPKSKFPLKSIINNPILIAVLFGLICSSINLEIPQFIYQSGHYLAQMTLPLALICIGGSLYWKNFRHNRKEVIWASLCKLILMPLIGTSLAITLEFRGQDLGLIYLMLSAPTAVSSYVMAKKISNYGAMAAEIIALSTASSTIIITLGLILLKTTGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI6</accession>
    <name>A0A1D3RMI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01466_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000330">
        <property type="protein sequence ID" value="SCN46856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="159" mass="18184" checksum="117BB480C654DE22" modified="2016-11-30" version="1">MRVFVSHQKADSELAGQISYHLKVNHQIDCYLDLIDPNASRAGDQLGDYLRNEMGKCTQLMAVVSENTKSSWWVPWEIGIATEKDYPIATFAGDNTVLPEYLKKWPYLKTQSNLDDYARATKAAAREFNLRKSYALDTAASRHSSTQEFYRTLRASLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ0</accession>
    <name>A0A1D3RMJ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate dehydrogenase iron-sulfur subunit</fullName>
            <ecNumber evidence="6">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_179626_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="6">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000351">
        <property type="protein sequence ID" value="SCN46892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 6" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="7">
        <location>
            <begin position="28"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="261" mass="29680" checksum="ACB273DB0C06038D" modified="2016-11-30" version="1">MVEFTLPKHSKVQKGKHFLAAKGVTRIKRVEVYRWDPDTDENPRIDSYEIDLDQCGAKVLDLIIKIKDEVDSSLTFRRSCREGVCGSCSMNINGKNTLACIKPIADIKGTVKIFPLPHMDVVKDLVADMTHFYAQYSSIKPWIKTQTPAPADSERLQSIEERKQLDGLYECVLCACCSTSCPSYWWNSERYLGPAVLLQAYRWINDSRDENVGARLDELEDPFKLYRCHTIMNCTDTCPKGLNPAKAIGEIKKLLLIRQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN4</accession>
    <name>A0A1D3RMN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_61083_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000309">
        <property type="protein sequence ID" value="SCN46819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4560" checksum="1E350DB7CA6C5BC4" modified="2016-11-30" version="1">MTVKVMETIHCHRYVKPITVKGMENETCVKSKTPPNASVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ3</accession>
    <name>A0A1D3RMQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_107087_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000384">
        <property type="protein sequence ID" value="SCN46934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="47" mass="5121" checksum="8AEEA9258D55C0B1" modified="2016-11-30" version="1">MLATEPFKAFHSAQATIAGIETAHMIRKGQLSEENIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS5</accession>
    <name>A0A1D3RMS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_159650_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.4.1.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000424">
        <property type="protein sequence ID" value="SCN46980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="53"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="181" mass="20491" checksum="7210C795D983353D" modified="2016-11-30" version="1">MRSDEWHKALRLLFFFQPFIRFLVYCMSSSIKLSIVFLNFNKLTETRFTCLALQKLCAKRPDIELIAVDNGSQDGTNEYLQAQTHITSISLADNTGIAGYNIGFNRARGQYILVLDDDSCPANLAGIDHALALLERRKDIGVIAAHIQMPDGSPQWSWHLPKNAAPSVSPFFHWLRLYHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT2</accession>
    <name>A0A1D3RMT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_47467_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000308">
        <property type="protein sequence ID" value="SCN46818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4649" checksum="0F2246132F15199E" modified="2016-11-30" version="1">MILFYAHWEIKGELYQNLPINATGIPQLAYACDRTLHCQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT4</accession>
    <name>A0A1D3RMT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_48536_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000425">
        <property type="protein sequence ID" value="SCN46982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4824" checksum="0A5B8E2F82246EEA" modified="2016-11-30" version="1">MKKAGDLAARLELLNKKAVKRGRKAYVNHTIVSVDDIHIEYTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMU3</accession>
    <name>A0A1D3RMU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclohexadienyl dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02129_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.3.1.12" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000429">
        <property type="protein sequence ID" value="SCN46992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="235" mass="25891" checksum="E3104AADF06C0AFE" modified="2016-11-30" version="1">MAEAVTGADCIVIATPVGAMPVIFKQLAPCWSDEALYMDAGSTKGNVVAALQDVFGFIPTNFIPAHPIAGAENSGVEAALDDLFQNRRLILTPAEQADPDFLCVAQNFWQAIGSDVSLMSVEQHDAVLAATSHLPHILAFSLVDLLGKKDETVDIFKYAAGGFKDFTRIASSDPTMWLDICMANKAHIMPLIQELCMELQGIKQMLEQNQTKELYDTFTYARNARQRFLDQYQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMU8</accession>
    <name>A0A1D3RMU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_104983_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000343">
        <property type="protein sequence ID" value="SCN46879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="171"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="299" mass="34620" checksum="C2DC0186B9E9C556" modified="2016-11-30" version="1">MAYEESRQYVDFYNQYKYDQNTHTFLVFQEEIKDKLKNSHFIILEFYNEKHNLLLTVGAVDVGKIKDELIRKDHKVQMDDNINYKTFFVHNAFTNELYMEVEIPFTENGSKLNNGFLKGIYKVSSSEIKSMIYDAFIVLAQYIAIIIFTTLVLYPVIIHLNKDLIRSTNNLSHANITLLKVLGGAIAKRDSDTSAHNYRVTIYAICLAQALKLKENQIRSLIKGAFLHDVGKIGISDNILLKPSKLNAKEFKEMQRHVIYGVDIIKHSEWLNDATDVVKFHHEKFDGSGYFNRGCCRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX1</accession>
    <name>A0A1D3RMX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04316_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000451">
        <property type="protein sequence ID" value="SCN47030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5395" checksum="6C3D0A4BE131C85F" modified="2016-11-30" version="1">MEATDLIGQRYKIEEMQKLENIRGICPLGQIVYLHAYRDTNKVITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ4</accession>
    <name>A0A1D3RMZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix, Fis-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_391329_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000463">
        <property type="protein sequence ID" value="SCN47042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="82" mass="9286" checksum="265A8E20C4649F57" modified="2016-11-30" version="1">MLLDPIKAFVKTITFDNGKEFTLHEKIAEALDCDTYFTKPYSSWERGQNENANGLLRQYFPKAMELIDVTIAENQGNGALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN08</accession>
    <name>A0A1D3RN08_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Cell division ATP-binding protein FtsE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsE</name>
        <name evidence="8" type="ORF">BAZMOX_70760_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the ABC transporter FtsEX involved in cellular division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Forms a membrane-associated complex with FtsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000350">
        <property type="protein sequence ID" value="SCN46888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005286">
        <property type="entry name" value="Cell_div_FtsE_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02673">
        <property type="entry name" value="FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="220" mass="24488" checksum="70F42250140E018E" modified="2016-11-30" version="1">MLSFDHVFKRYADAGDTLIDLSFHLDQGEMAFLTGHSGAGKSTLLKLVAVIERCTRGQILVDGQNICRMHDRQVPFLRRKLGLIFQDYKLLFDRTVFDNIALPLIVAGVGRHEVARRVRAALDKVGLLGKENKYPLALSGGEQQHIGIARAVVNKPALILADEPTGNLDPQLSAEIMRLFEQFKQVGVTILVATHDIELVTKLDHRVLQLDHGTLIKHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN32</accession>
    <name>A0A1D3RN32_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_06086_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000338">
        <property type="protein sequence ID" value="SCN46867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="237" mass="25972" checksum="94AE38D16DDE9D47" modified="2016-11-30" version="1">MPLVVQETISLDEGCAHYVRTVLRLKKSYSIILFNGLGGEYQAEIMVVSRKQVLVKILSFVDRDVESPLQVLLGLGVSRGERMDFSVQKSVELGVMKITPLISERCVVQLKGDKESNKIRHWQKIAQHAAEQSGRTVMPKIEAVEFLAGWAIAQSGLKVFLDPFATQTLQDLQPEGNKVTLLAGPEGGFSEQERETAKQAGFIPVQLGPRVLRTETAALAALTAVQVLWGDLGCTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN78</accession>
    <name>A0A1D3RN78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_32770_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000367">
        <property type="protein sequence ID" value="SCN46917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="162" mass="18732" checksum="1BF5E8861AAB44C0" modified="2016-11-30" version="1">MGRLWQTLILSQWKPIFTDLPVESLVYAHQADYYQALQNSTEQSDSAPFIEFMLRRILESCLATSEQKNDHVSDRVSDQVNALLKGLNHQTAMTASELMTQLGLKHRPTFRKNYLTPALQNNWIEMTQPDRPKSPTQKYRLTDRGLVLIKNLAHKHKQTSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN83</accession>
    <name>A0A1D3RN83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Octaprenyl-diphosphate synthase / Dimethylallyltransferase / Geranyltranstransferase (Farnesyldiphosphate synthase) / Geranylgeranyl pyrophosphate synthetase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_12860_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000440">
        <property type="protein sequence ID" value="SCN47009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="298" mass="32295" checksum="A2C3934E2C1E94A3" modified="2016-11-30" version="1">MSNALKEYLVASQERVEKALDLRLPANNILPKRLHDAMRYSALDGGKRMRPMLTYSVGKALGIAADVLDGPACAVEFIHVYSLIHDDLPAMDDDDLRRGKATSHIQYDEATAILAGDGLQTLAFQVLANDDSMQASAATRIKMIQALAKASGSQGMVGGQAIDLESVGKKLTLPELENMHIHKTGALIRVAVQLATLSQPDLDPAVAAKLDHYAKCIGLSFQVKDDILDEESDTATLGKTQGKDQDNDKPTYPALLGLEGAKEKAQNLHEQALESLADFGPEADLLRDLSLYIIQRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN93</accession>
    <name>A0A1D3RN93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_38472_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000448">
        <property type="protein sequence ID" value="SCN47019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4472" checksum="85EC688B1A9D64EB" modified="2016-11-30" version="1">MANFPVAYCGLKIITSLSLRFPDFQRLKPMLELSACYPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA2</accession>
    <name>A0A1D3RNA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome (Plasmid) partitioning protein ParA / Sporulation initiation inhibitor protein Soj</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_20759_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000529">
        <property type="protein sequence ID" value="SCN47124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="4"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="255" mass="29285" checksum="A51E3C87DC42DB11" modified="2016-11-30" version="1">MTCIVSFSNSKGGVGKTTSVLGMGCCLAEKGKKVLLIDLDHQGNLSDDFGRGDEDYTITDLFENPKFDTNKIIYKALDDGNEIENLYIIPADITLAVEARSAERYRYRLQILDDGIKRLKETFDFILIDCRPAIDLSIENALLISNVIIIPVDMDRRAVKGIDDLLEVVDEVKRKQQFVYTLIYTKVDNRNKKMLAATKNRIKEKKYPVLNTRIGISEKYKQASEEHRPVVHFAKNERPHLDYMELTKEFLEFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA9</accession>
    <name>A0A1D3RNA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide TPR_2 repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03040_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000555">
        <property type="protein sequence ID" value="SCN47153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="57" mass="6356" checksum="980BB3493C7686A2" modified="2016-11-30" version="1">MTTRIRPYFKAWHIISGLSDGLVAQKIYNDGIDILVDLSGHTSKNRLAVFAWKAAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG9</accession>
    <name>A0A1D3RNG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminomethyltransferase (Glycine cleavage system T protein)</fullName>
            <ecNumber evidence="2">2.1.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_90188_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.2.10" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000619">
        <property type="protein sequence ID" value="SCN47255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="75" mass="8087" checksum="C929376FB79BD5E1" modified="2016-11-30" version="1">MLQTKVTGKDKISFIESLTVADVESLNENQGTLSVFTNDTGGILDDLIINKTTDGYLYVVSNAGCAEKDLTNMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH4</accession>
    <name>A0A1D3RNH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_00434_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="3">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="257" mass="28482" checksum="7ACE0E3A6BDA19A5" modified="2016-11-30" version="1">MHIDEEMMSEIKELHAAINPVETLFVVDSMTGQDAATTAKAFNDALPLTGVVLTKTDGDARGGAALSIRHVTGKPIKFVGVGEKTDALEPFYPDRMASRILGMGDMLSLIEDIEQKVDKDKAAKLAKKLQKGKGFDLSDFVEQLEQMESMGGVGAMMDKLPGINDVPQGMRDKVNDKELARQIAVIRSMTNQEKRYPDLIKGSRKKRIAAGCGQELQDVNRVLKQFKMMQKMMKRFKKGNMANMVRGIKGNMKGMRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ4</accession>
    <name>A0A1D3RNJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_239060_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000615">
        <property type="protein sequence ID" value="SCN47250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="72" mass="8457" checksum="09E524D8A57D2BC8" modified="2016-11-30" version="1">MSEPTPHNQQAFVVLLKQIQHVRQNVFFHINTTLIDLYWHIQKALIENMKQFILELGGDSLFSSWFIDVSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN4</accession>
    <name>A0A1D3RNN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_06368_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000636">
        <property type="protein sequence ID" value="SCN47290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="71"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="405" mass="47126" checksum="74E80841023C5D93" modified="2016-11-30" version="1">MLELSKACVKQLETKDAVLMPYYDTSDPRYFDKRKKFGKGEKKMTETKKKPAKKTAKKPPSQSIKSIQHDLFSDFLTNDVSEVSNTVEYWERIPKYFLSPQEQKRLRTAEGLAKPYTQEYILRGQNGEPLLYKVRVQPALIEQNNGEFIAFFPTKAEEIIEEVLKKIFTEQNLGIHDAKNSESWVKFSYSMINKELRKNKCSRTHQQIKHSLEVMSKCILTVFEDGEEIYSNPIINNYIKVDRKQYLGNTKALHVAQLSVFISHAVNTLQYRQFNLKRLTSCKEQLSGWILRRLIERFTYASLITTHDLYYSSMKAASLLLRSSREIDNRVKVIKALEELQENGTIYSYEVEEKREGRKIVDIKYRITPSSEFSSEQKAANKRANIIGQKAVKNDLQIVDKSKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN6</accession>
    <name>A0A1D3RNN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_358233_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000522">
        <property type="protein sequence ID" value="SCN47118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="82" mass="9458" checksum="0209AB0F572471F5" modified="2016-11-30" version="1">MDKLVIKSDHLKANIQSELKRVSADNEQLQQQITTLTQQLSEAEEKIQSLAEVQDRQQATIQKLIKILKGVNTKIMHLYDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP5</accession>
    <name>A0A1D3RNP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipopolysaccharide ABC transporter, ATP-binding protein LptB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_266522_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000497">
        <property type="protein sequence ID" value="SCN47087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCA_ABC_TP_C" evidence="3">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="81" mass="8949" checksum="0E8E1E2B85842C99" modified="2016-11-30" version="1">MDEPFAGVDPISVIEIQKIIAHLKDRNIGVLITEHNVRETLGICDRAYILNVGQVIAEGSSADIVANEEVRRVYLGENFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP7</accession>
    <name>A0A1D3RNP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_402286_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000637">
        <property type="protein sequence ID" value="SCN47293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920266" evidence="1">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="106" mass="11544" checksum="51DFA7D39C5BD475" modified="2016-11-30" version="1">MLLRILMFVCFFYTSQLLAGSAQPSVAIKDPIIGDGVSKYVKSSLDINQIRAEMESSFRATRKFRVLSRNKATLGAILDEQNFAQSDLAKGDAAASGELNKVLSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP9</accession>
    <name>A0A1D3RNP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_02505_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000631">
        <property type="protein sequence ID" value="SCN47274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="160" mass="17282" checksum="B27BE382E7EA614E" modified="2016-11-30" version="1">MKNIENPVVSIHYTLTNKAGEKLDSSIGSEPLTYIQGAGNIIPGLESALADKSVGDKLTVTIEPKDAYGERNEEHIQTVPKEMFQGIDNIEVGMQFQADSSNGPAIVTITAVEGDQVSIDGNHPLAGEQLTFDVEVMDIRPATETEMEHGHIHGESCNHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ5</accession>
    <name>A0A1D3RNQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_385711_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000540">
        <property type="protein sequence ID" value="SCN47138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="67" mass="7531" checksum="EF656C8F067D27E6" modified="2016-11-30" version="1">MELIREDLSLHYDPLPIARIDTGVGQAVARHILTHKHEPNGSVASISESEERLVFRHNYPAKAINCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV9</accession>
    <name>A0A1D3RNV9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gyrA</name>
        <name evidence="12" type="ORF">BAZMOX_02254_1</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000572">
        <property type="protein sequence ID" value="SCN47188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="11">
        <location>
            <begin position="11"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="849"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="492"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GyrA-box" evidence="8">
        <location>
            <begin position="560"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="860"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="874" mass="97002" checksum="8B22637847B72911" modified="2016-11-30" version="1">MSEFAKEITVVNLEDEMQKSYLDYAMSVIIGRALPDVRDGLKPVHRRVLYAMSVLGNDWNKPYKKSARVVGDVIGKYHPHGDTAVYDTIVRMAQPFSLRYMLIDGQGNFGSVDGDSPAAMRYTEVRMAKIAHEMLADLDKETVNFASNYDDSESEPVVLPAKVPALLVNGSSGIAVGMATNIPPHNLAEVISACLALIDNPDVSIKDLMEYIPGPDFPTAGIINGVSGIYDAYTTGRGRAHIRARSHFEDFKDGSRQAIIVTELPYQVNKARLLEKIAELVKEAKIEGISGLRDESDKDGMRMVIELRRGEVPEVVLNNLYKQTQLKTVFGINMVAILDGRPKCMNLKEILHAFVDHRREVVTRRTIYLLRKARERAHVLEGLAVAMSNIDEMIALIKAAANPAEAKAGLLSRNWDAGLVAILLENADESRSRPDGLELIFGIHGAEYRLSEAQASAILDLRLHRLTGLEQEKIVNEYKQLLELIDGYLEIIGSATRLMEVIREELENIKEEYADERRTEIVRDVLSLSEEDFITEEDVVVTMSHEGYVKTQRLEDYQAQRRGGRGKSATATKEEDFVEKLVVANTHDTIMCFSSAGKVYWLKVYQLPIASRASRGKPFINLLPLEKDEQISAMLTVREFSENQFVFMATAAGTVKKTPLKEFERQRSNGKIAIDLREGDSLVGVAVTDGEQNILLFSSNGKANCFSETDVRSMGRTATGVRGMRLGEGQKIISMITSSEGTVLNVTENGYGKRTKLEEFTRHKRGGQGMIAMQTSERNGNVVGAVLVSDNDEIMLITSGGVLVRTRVNEISIVGRNTQGVKVIRLDATEKLVGVDKIDGLVEELDESVDTEAQEIIDEPLDTLDPHRGEPENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW4</accession>
    <name>A0A1D3RNW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Argininosuccinate lyase</fullName>
            <ecNumber evidence="2">4.3.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_160332_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.3.2.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000550">
        <property type="protein sequence ID" value="SCN47147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="1">
        <location>
            <begin position="13"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="105" mass="11754" checksum="7EA68D36E563E106" modified="2016-11-30" version="1">MTTANKDKLSSARFSQATDAFVEIFTASVDFDQRMAQQDIEGSIAHATMLCTIGILTEAERDSIFQGLEQIKDEIERGEFQWSIQQEDVHMNIEARLTELIGIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW7</accession>
    <name>A0A1D3RNW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Endonuclease</fullName>
            <ecNumber evidence="6">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_158182_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000677">
        <property type="protein sequence ID" value="SCN47336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="Extracellular_endonuc_su_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="PTHR13966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920256" description="Endonuclease" evidence="7">
        <location>
            <begin position="22"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease_NS" evidence="9">
        <location>
            <begin position="38"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="NUC" evidence="8">
        <location>
            <begin position="39"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="221" mass="25275" checksum="69DA0A123275E7C7" modified="2016-11-30" version="1">MNLLIRTTIISVIATASNANATNINQFINTRSCDQVIDKKFYKICYDYKAKGAKFVAYTLKGKNVGAVNIKKRPSFYPEKSIPSRYRTYPNDYTHNEFKADRGHLAPDAAFDWSKDSLDSVYSMANIIPQYRSINRHTWIKAERYARSIAIKLGEVTVINGVEYGSQRMKKSGIAYPKGYWKMLCNDAKGFKRCLYYKNSKTIKTKGDKLKDHVVDCSTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX1</accession>
    <name>A0A1D3RNX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_114231_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000680">
        <property type="protein sequence ID" value="SCN47344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="5216" checksum="640B3EE9C79D018E" modified="2016-11-30" version="1">MRELKVRTPFEAVECWYRMNPELFIKSPDMFRSGLLKNHGTTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX4</accession>
    <name>A0A1D3RNX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="7" type="ORF">BAZMOX_04778_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000741">
        <property type="protein sequence ID" value="SCN47425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 7" id="KW-0346">Stress response</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="17"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="201" mass="22277" checksum="2DF0D0447A34375F" modified="2016-11-30" version="1">MSNKQNTAESKTDSELIEEVLEQVADLDNEEAEAENAQEADVSVAELQARLAKAEAKAAENWDKVLRTQAEMENLKRRTQKDLDNAHKYGLEKFAKELLSVIDSLELGIQAATSDAPEVVKLREGSELTVKQFENVFAKFNIEAIDPLGQPFNPEQHQAMTMQPSADVEPNTVINVLQKGYILNGRLIRPAMVVVSQAATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP03</accession>
    <name>A0A1D3RP03_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_19938_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000764">
        <property type="protein sequence ID" value="SCN47455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019707">
        <property type="entry name" value="DUF2582"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10771">
        <property type="entry name" value="DUF2582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="6961" checksum="976104120569094C" modified="2016-11-30" version="1">MSDSIGNSAGIIWKFLNDNGPSSANKISTETGLSKNNLQRGIGWLACEGKLSFEMNGRTETISLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP28</accession>
    <name>A0A1D3RP28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_84982_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000582">
        <property type="protein sequence ID" value="SCN47207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="53" mass="5844" checksum="8E125DD61F62CDB1" modified="2016-11-30" version="1">MDEAKAHFKNPPKFDPNNFHPKKCEGRNETSFNGLVIPQNAGGIVTSTDSDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP47</accession>
    <name>A0A1D3RP47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaK</name>
        <name evidence="9" type="ORF">BAZMOX_04778_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000741">
        <property type="protein sequence ID" value="SCN47424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="602"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="609"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="6">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="645" mass="68973" checksum="96AE3A85A1F23BAD" modified="2016-11-30" version="1">MAKMIGIDLGTTNSCVAVLENGKARVIENSEGARTTPSIIAFTKDDEVLVGQSAKRQAVTNPENTLYAIKRLIGRRFKDSVVQKDIKMVPYKIVEAENGDAWVECHGKKMAAPEVSSRVLIKLKKDAEAFLGETVTEAVITVPAYFNDSQRQATKDAGRVAGLDVKRIINEPTAAALAFGMDQTPGDSTIAVYDLGGGTFDISIIEIADVDGEHQFEVLATNGDTFLGGEDFDLRIIDFLAEEFKKDNGIDLHNDPLALQRLKEAAEKAKIELSSAEQTDVNLPYVTADASGPKHLNVKLTRAKLESLVDDLIERTKGPCLTALKDAGLAAKDIGHVILVGGQSRMPKVQKMVESIFGKEPRKDVNPDEAVALGAAIQAGVLGGDVKDVLLLDVTPLSLGIETMGGVMTKLIEKNTTIPTNASQVFSTADDNQTAVTVHVLQGEREVASGNKSLGRFDLSDIPPARRGVPQIEVSFDIDANGILNVSAKDKATGKEQSIIIKASSGLSDEEVDRMVKDAEAHAEEDRKVTELVSARNTAEGMINATEKSVEELGEKVSAEEKTAIEAAIEELNEAVKGDDKEAIEAETTALTELSGKLAERAYAQQAGAEEGNSGSEGSVEQASAEADDSVVDAEFEEVKDDDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP53</accession>
    <name>A0A1D3RP53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase and inactivated derivatives</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_37982_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000776">
        <property type="protein sequence ID" value="SCN47471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="112" mass="13178" checksum="7F523444736215F3" modified="2016-11-30" version="1">MRQQHQEQKVNSLAFVVMPDHFHWLIALQNNCKLEQVMRSAKGISATQIQKIRRKRGKLNQNQALWQDGYHDHAVRKEEDLQHLARYIVANPLRAGLVKKIGDYPLWDAVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP76</accession>
    <name>A0A1D3RP76_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_32698_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000791">
        <property type="protein sequence ID" value="SCN47493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920278" description="Cytochrome c domain-containing protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="24"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="111" mass="11664" checksum="EDB8133E2386D9C7" modified="2016-11-30" version="1">MKKLLLAVSTVALLGLSAQASADKELKVGKKIYDRAFGRGCGACHDISSNPQLTALIKAGELSEESFAKTLKEGKNGMPKAMAAIMAVGPVKKAGYSEDEAIAAVYKYLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP90</accession>
    <name>A0A1D3RP90_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="7">3-dehydroquinase</shortName>
            <ecNumber evidence="5 7">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroQ</name>
        <name evidence="11" type="ORF">BAZMOX_01131_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="5 7"/>
    <dbReference type="EMBL" id="FMJP01000799">
        <property type="protein sequence ID" value="SCN47511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="102"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 8">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7 10">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="148" mass="16408" checksum="A534D6A69C04BBCB" modified="2016-11-30" version="1">MAKITILNGPNLNLLGIREPGLYGNQTLSDIQHSTEELAEKLGHLLNFEQNNAEHEIIELIHQAFADQVDFIIINPAAFTHTSIAIRDALLATKIPFIEVHLSNVHAREPFRKHSYLSDIAQGVICGLGALGYELALQAAHQTLLERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP94</accession>
    <name>A0A1D3RP94_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplW</name>
        <name evidence="6" type="ORF">BAZMOX_04315_3</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000822">
        <property type="protein sequence ID" value="SCN47555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="98" mass="11110" checksum="9B2B30A742A9A8DF" modified="2016-11-30" version="1">MSIEFNLSNVIKAPVISEKSTVAAENQNRFVFKVASEATKLQVKKSVELMFNVEVEKVQLLNVKGKTKRFGRFMGKRSNWKKAYVKLKPGNDIDFSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP97</accession>
    <name>A0A1D3RP97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03955_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000670">
        <property type="protein sequence ID" value="SCN47328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="5019" checksum="52BC152FDBD93096" modified="2016-11-30" version="1">MFIRYFQSLAHAHFALRHLERKYTPELVKLNYQKWIARQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC3</accession>
    <name>A0A1D3RPC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribulosamine/erythrulosamine 3-kinase potentially involved in protein deglycation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_47653_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000709">
        <property type="protein sequence ID" value="SCN47389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="PTHR12149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="227" mass="25886" checksum="7462E764CB3ABB77" modified="2016-11-30" version="1">MKLWSVVVSKIEQVTGQTFGLQKVEAMQGGDINRVYRLQGSTQSYFVKLNKASLLAMFEVEALGLHDLASTHTLRTPKPICSGIVGEDAFLVLEYVALQSLSSRSQQQLGEQLAQLHQVQQSYFGWHHDNYIGSNLQKNTRENDWVHFWQEQRLAVQLELAAQNGYAGKLQTLGAELYGLVPQFFSVTKPKRLYCMEIYGQVMQQQMNRGRQLFMILLATMVIERLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG4</accession>
    <name>A0A1D3RPG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00742_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000881">
        <property type="protein sequence ID" value="SCN47625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="80" mass="9181" checksum="92B94241B328F540" modified="2016-11-30" version="1">MSDSLSSNAIIYAILSIDAEIALQKDYLESSDVLPEERENEEGILDDLEQAFMEFIEFYKSCRKQDKELPALDELLTHPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPG6</accession>
    <name>A0A1D3RPG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iso-IS1 ORF2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_315435_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase 27 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000807">
        <property type="protein sequence ID" value="SCN47536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005063">
        <property type="entry name" value="Transposase_27"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03400">
        <property type="entry name" value="DDE_Tnp_IS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="72" mass="8567" checksum="F7D860665786D0A0" modified="2016-11-30" version="1">MIGGAYERNLEKNEHEIGKQNTQKIERKNLSFRTWIKRLTRRTICFSKIEKMHDIVIGLLINKVEFGRDIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI7</accession>
    <name>A0A1D3RPI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00412_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="107" mass="11905" checksum="9B26DFB774A03ECB" modified="2016-11-30" version="1">MKQYFGFRYFSSDKTTAGKPHKQSGNVSIAGECIVFNSKQQLEEWLNQENLSTPSDSGGGKRIKSSRADLRNKCLGLTMANFNRMLLRNTVTEDTEQPSTAATNKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK3</accession>
    <name>A0A1D3RPK3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS2020, hypothetical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_55186_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000910">
        <property type="protein sequence ID" value="SCN47665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="6978" checksum="D6B28E0D01292830" modified="2016-11-30" version="1">MNNIIEQDPRFIKKITKPMMGFKAFHSAQATIAGIEAAHMIRKGQLSEENMPAYKQFRALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ2</accession>
    <name>A0A1D3RPQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02898_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000884">
        <property type="protein sequence ID" value="SCN47634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5365" checksum="24B5CA95C0EEA354" modified="2016-11-30" version="1">MIGLGASITKIDSPHGESIVPQCTPLTVIKLRAIEYGAQCFSLLFSAMKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ6</accession>
    <name>A0A1D3RPQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_00742_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000881">
        <property type="protein sequence ID" value="SCN47626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="324"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="451" mass="51722" checksum="84601086A5BC9C3C" modified="2016-11-30" version="1">MPELALADVRLEKKFPALELTPEERQYLNKKSQLTMCVDPDWMPYEKIENGQHVGMSADFMRLFAKKINIPIVLVPSRSWRESLALGKQRQCDIFSLILATPKRQQFLDFSEPYIGFPLVIATGYEQIFINDIRSILDKRLGIQKDYAYAELLRFQYPGIHLVKVDSLAEGLAKVNSKQLFAMIGSLPSIAYIFQKEHIGELKITGKLDHIWQLGVGVRNDEPLLAGIFNKAIASVQNTERQAISDRWMTTRYELGTDYTILIKVVLAFALVFAFFLYHHFQLRKYNRLLKHLSVTDKLTNISNRTDLDEKLERNLYLAERYNHPFSLILLDMDHFKSVNDTQGHLVGDYVLQTIATLLKEHIRVVDIAGRWGGEEFLIICPEQTAEQAMILAEKLRVIIADFPFKYGLQLTCSIGVASYRKQDSSDSLIKRADDALYQAKNLGRNKVCQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR1</accession>
    <name>A0A1D3RPR1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_25926_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000788">
        <property type="protein sequence ID" value="SCN47488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="7">
        <location>
            <begin position="179"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="504" mass="59284" checksum="630ECACCE8DB924B" modified="2016-11-30" version="1">MAYSSLILFLTFIFVLMYQEFSGKYSRLTTIFSIISTSIVFSIPIFYIIYAINFDTKITRDIIYALFQTNLQESLEFSETYLSEYQIIFIIFLISTTGVLLLKQENKESTKIEKSLLMFLLIYIFSNLIAYRHDIHLLIYLKNGIQEYKKELQLFKKEQEKMKNGYIQFYANKTNTGETYIVVIGESLNKYHMGIYGYSRQTTPLLKKLSQTYLKFEHSYSNHTHTMPVLSLSLTEANQLNKKIFYNSLSIIDILNKANFQTYWISNQNMYGEWDNLVSIIAHQADHLTSINHSRGKTTRTQKFDSEVLKHIKKILKQNDHSNNKVIFVHLMGSHGDYCQRYPKKEFSKFNGIVNRSINCYDNSVLYNDFVVSNIMDILKQDSGIRGFVYMSDHADDVDRGLGHNSSKFTYDMTQIPLIMWFSDTFKNKYSLSYSNLLENKNKLFSNDFFYDTLLGIMQVQTQHYNSSYDLSSNQYKLEDNKAFTLHGKKRYIDKNNTFYLPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS2</accession>
    <name>A0A1D3RPS2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="2">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphoriboisomerase A</fullName>
            <shortName evidence="2">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpiA</name>
        <name evidence="3" type="ORF">BAZMOX_04294_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000755">
        <property type="protein sequence ID" value="SCN47437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="PTHR11934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="28"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="83"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="219" mass="23389" checksum="CB804D5E2521AA00" modified="2016-11-30" version="1">MTQDESKRKAAEAALPYIKDVAILGVGTGSTVNHFIDCLADFDLTKDIKGAVSSSIATTERLKKIGIPVMELSESGNLDVYVDGADETNALKQLIKGGGGALTREKIIAGASKKFVCIVDESKTVKVLGKFPLPIEVIPMARSFVAREIVKLGGQPIWRENYVTDNGCEIIDVHNMEISEPLALERLVNNIPGVVTVGIFGLRPADVVLVAKASGVETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS4</accession>
    <name>A0A1D3RPS4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1244 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_07964_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000929">
        <property type="protein sequence ID" value="SCN47700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023163">
        <property type="entry name" value="SMc04008-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036810">
        <property type="entry name" value="SMc04008-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06844">
        <property type="entry name" value="DUF1244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158757">
        <property type="entry name" value="SSF158757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1244" evidence="1">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="101" mass="11560" checksum="7C9FAD75C097FC7D" modified="2016-11-30" version="1">MNTTTQTELEAAAFRQLLAHLQAHTEVQNIDLMNLADFCRNCLAKWYLAAAEEQGVAMDYETARTYVYGMPYSEWKEQFQLKATAEQMALFESKKAAKVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU0</accession>
    <name>A0A1D3RPU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA-i(6)A37 methylthiotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_26533_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000801">
        <property type="protein sequence ID" value="SCN47518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="6">
        <location>
            <begin position="225"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="298" mass="33154" checksum="0AB7D5088C5595B6" modified="2016-11-30" version="1">MEGCSKYCTFCVVPYTRGEEISRPVQSVLEEITTLAEQGVREVNLLGQNVNAYRGEMNEGEIADFALLLHFVAAVDGIDRIRFTTSHPIEFTDELVDAFEAIPELVNHLHLPVQSGSDNILAMMKRGHTRADYLATMEKVKAVRPDISLSSDFIIGFPGETDQDFADTLDLIEQVGFDFSYSFIYSARPGTPAAEFPDDTSDDTKKERLSLLQKRLDEMTKAISNGMVDTVQTVLVEGLSKKNQLQVTGRTENNRVVNFIGHPRLVGQFVDVLITEALPNSLRGRAVESSLDKIIHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX4</accession>
    <name>A0A1D3RPX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7 8">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <shortName evidence="7">MECDP-synthase</shortName>
            <shortName evidence="7">MECPP-synthase</shortName>
            <shortName evidence="7">MECPS</shortName>
            <ecNumber evidence="3 7 8">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ispF</name>
        <name evidence="10" type="ORF">BAZMOX_320749_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the IspF family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="3 7 8"/>
    <dbReference type="EMBL" id="FMJP01000931">
        <property type="protein sequence ID" value="SCN47704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="PTHR43181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YgbB" evidence="9">
        <location>
            <begin position="2"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="35"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="62"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="101"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="7">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="158" mass="16917" checksum="77C61BC8FD91F06D" modified="2016-11-30" version="1">MIRVGQGYDVHRFIDDGDVILGGVKIPYKQGLEAHSDGDVVLHALCDALLGAAALGDIGKHFPDTDPEFKGADSRVLLRHVYGIVQEKGYTLGNADITIIAQAPKMAPHIVAMCTHIAEDLSVNLDCINVKATTTEKLGFEGRKEGIAVQAVVLINKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY3</accession>
    <name>A0A1D3RPY3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 11">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplV</name>
        <name evidence="12" type="ORF">BAZMOX_04315_6</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8 11">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000822">
        <property type="protein sequence ID" value="SCN47558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="111" mass="12282" checksum="BCE52DEA8FCE376A" modified="2016-11-30" version="1">MEVLAKLSNAPLSAQKARLVADQIRGLKVEEALNVLKFSTKKAAEIMKKVLESAVANAEHNESADIDELKVSSVFVDEAPTLKRFRARAKGRANHILKRTCHITVKVAEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY4</accession>
    <name>A0A1D3RPY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_309186_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000933">
        <property type="protein sequence ID" value="SCN47706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920286" evidence="1">
        <location>
            <begin position="24"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="61" mass="6892" checksum="B982073C911780D4" modified="2016-11-30" version="1">MFISLRKYTRVTLYIVIAVTLNACTTTGTAQITDQAIVSWGADEGIKRLEESQYKVEFFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ6</accession>
    <name>A0A1D3RPZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ORF">BAZMOX_114598_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000797">
        <property type="protein sequence ID" value="SCN47507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="167" mass="18854" checksum="27FEE90A93DDB4E3" modified="2016-11-30" version="1">MSILSILEFPDPRLRTVAKPVKEVDKALGGLVDDMFETMYEAHGVGLAATQVNIHQRIIVIDISEEKDQPVCLINPEIMDSLGEEESDEGCLSVPGIFEPVTRAETIKVKALDKRGESFELEADGLLAVCIQHEMDHLLGKLFVDYLSPLKRQRIKKKMQKMHKREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ27</accession>
    <name>A0A1D3RQ27_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgA</name>
        <name evidence="10" type="ORF">BAZMOX_07384_1</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01001038">
        <property type="protein sequence ID" value="SCN47855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="9">
        <location>
            <begin position="3"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="8">
        <location>
            <begin position="294"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="477" mass="53706" checksum="B17A3D9B3C9D3122" modified="2016-11-30" version="1">MKKILFVTSEVHPLIKTGGLADVAGSLPIALSELDQDIRIIVPKYYGIKLTEEPLYRSTIRINNRDVNIFETQLPNSHVIVWLVDCPEFFSIPGNPYTDEFGNAWSNSAEKFALFCRVAVEVAQNRAYLDWKADIVHCNDWQSGLVPALLTLEPLRPSTVFTIHNMAYQGIFPQETFHALGLPGQLWQPSALEYHNKLSFIKGGISCADHITTVSPNYALEIQTADFGYGLEGLLQHRRHDLNGIINGIDLEQWNPAIDKRIAQTYTVETLAKKTLNKTAIQQKLSLPEEPSIPMIALISRLVEQKGIDLVIQCLENLVQYPLQFVLLGAGNKSYEHQLKNLSLLHPEKISVTIGYDEDFAHLIEAGADMFLMPSRFEPCGLNQMYSQRYGTLPIVRRTGGLADTVVDAMPDSIAQQTASGFVFDEASVSAMLEAIKRALFVYDNKKTWQKIQKIAMQKDFSWQQSAEQYLALYRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ52</accession>
    <name>A0A1D3RQ52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_25418_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001015">
        <property type="protein sequence ID" value="SCN47821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4393" checksum="678E7A9FC245C6F4" modified="2016-11-30" version="1">MLLAITDFNAAARAASHGERTRGLVVRDSRRAVVLSEPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ61</accession>
    <name>A0A1D3RQ61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phage integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_30228_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001023">
        <property type="protein sequence ID" value="SCN47833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="7"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="113"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="310" mass="35795" checksum="6DEE93CDD3F50B7E" modified="2016-11-30" version="1">MANSIELKFRKIQKEFLEFLKYTKGHADSTCYNYNSDLNIWIAWLTEEELDWRKCQPVDVEHFVSYLSKKGTGAHAVARKISCLSTFYKWAKRREYVQDDPIYLIDKPKRPSRMPVWLEQEEQNDFMKAMRNYDDIPETIFGRSKTSSVKIRQRYELLFELIQKSGLRISEALRLKTSDVRVVDGVAKSVRVIGKGDKERQVPLPESFGRVFSVSIADKSRDEYLFAKKPGGKPVGQHAARAYLKKLVEKAGINKKVTPHKLRHTYATRLLEKDVQLIDIQALLGHSSIATTQIYTHAGQERLSKLVADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ67</accession>
    <name>A0A1D3RQ67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_40515_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000927">
        <property type="protein sequence ID" value="SCN47689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="268" mass="32111" checksum="F7FB2B200FCF121D" modified="2016-11-30" version="1">MKTILLVTVTLWATTCHARELWEIPVTEAMALHFQMKEDAFVRAQKARDIKNKIKIWSTCKETSERLKSQYYRLDAIRYNAQQIFEWQETYPEETDMYKDAKDAESQWLFLMNQVSSRLGIARTECKKKGTTPAVELERARRHWVWTIEDKNRAIRNKRHISIYYITHLFDKYADKTVMFAQEEVNWGERIYQDIVRYMYSISDAAIDEKLDVDYKQADEYLNEVIAAHKTKKRLEDGLYESLQIKKIKEVMEEWSTIQTLVDTMRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ90</accession>
    <name>A0A1D3RQ90_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="8">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="8">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">ImGP synthase subunit HisH</fullName>
            <shortName evidence="8">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisH</name>
        <name evidence="11" type="ORF">BAZMOX_12411_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="8"/>
    <dbReference type="EC" id="3.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01001086">
        <property type="protein sequence ID" value="SCN47915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="213" mass="23449" checksum="731B13540BD2D016" modified="2016-11-30" version="1">MSSVAVIDYGMGNLHSIAKALQHAAPDVDVRVVSDLKSILSADRVVFPGVGAMRDCMHALQETELNQVIAQVAQTRPLLGICLGMQALLTNSEENGGVECLNILPGQVKHFSEDLRTSNGERLKIPHMGWNQVEQHAHPLWEGVPQNSRFYFVHSYYAQPDSSVIVAGTTEYPENFACALAKDNIFAVQFHPEKSQTAGLQLLNNFLHWDGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA7</accession>
    <name>A0A1D3RQA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_19223_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001060">
        <property type="protein sequence ID" value="SCN47883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="50" mass="5340" checksum="FDC395E4ABA0BF5E" modified="2016-11-30" version="1">MTAPRDTNNLNDKIFYTTTTINKLGFKAALPQRQRHPAGVSGSIAVPGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA9</accession>
    <name>A0A1D3RQA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division protein DivIC (FtsB), stabilizes FtsL against RasP cleavage</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_23253_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000919">
        <property type="protein sequence ID" value="SCN47678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00599">
        <property type="entry name" value="FtsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023081">
        <property type="entry name" value="Cell_div_FtsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37485">
        <property type="entry name" value="PTHR37485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="91" mass="10635" checksum="E425A534AF39BAA4" modified="2016-11-30" version="1">MLIKFLIAILLIFIALLQHRLWQGDGGIAQTQQYQRQLEALQKQLAVKQQRNEVLKAEVQDLRKGQEAIEEIARYDLGLIKKDETFFQVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB4</accession>
    <name>A0A1D3RQB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein involved in initiation of plasmid replication</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_19223_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001060">
        <property type="protein sequence ID" value="SCN47881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="21"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="362" mass="41761" checksum="50D766621C5160C0" modified="2016-11-30" version="1">MTELELITKLDETVFLKPTGTVHITNSFSLIERKLLNVIVWHSQKHRFTSEEHSLPIRDVFYLLGLKESRNQDVIKSAIRTLLSTIIEWNILEADRAQEWGVCTFISSGKLVSGKLNYRLNPEIIEKINNPTLFAKIQLLIQSKFKKKHTLVMYEFFIDALSRKRKDYLRLVVKLDKLHSILGTENTPFKFFNRDVLKPSIREINSHTDLDVNNETLRLGRSIYEIVFEISKKKMFPMSLDFVDPEEGLPPSIQGEKKAIDILKEHGLNLSIAKALSKSFDYEHIIANIAYTELQVINGKVKNRKAFLVKAIKENYSGNETCNEESYSGVTRSEIEKNARPGESYNAAAERIKEDKKHSIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC8</accession>
    <name>A0A1D3RQC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_86659_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001044">
        <property type="protein sequence ID" value="SCN47864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="184" mass="20570" checksum="47B3824A0121AEE7" modified="2016-11-30" version="1">MIKNIYFIIAIQFLTLGTAYSNEKIPFFDGTTLKIPVVSTPERPGSLRNVEFKFTDGKWQLSGYKGRVPMPGIKKVEMFLTEELPIQGYLKIQGGGIGSSCIHLELIRQQLVGNTFEVFIDSDPRYPISACTRDIGFFTKIIPLPLYGLKRGEYKYTVNGGFSGVFSLPSDNNLTGNEVNVKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE3</accession>
    <name>A0A1D3RQE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fe-S OXIDOREDUCTASE</fullName>
            <ecNumber evidence="7">1.8.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_79250_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.8.-.-" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01001046">
        <property type="protein sequence ID" value="SCN47866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022946">
        <property type="entry name" value="UPF0313"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013704">
        <property type="entry name" value="UPF0313_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32331">
        <property type="entry name" value="PTHR32331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08497">
        <property type="entry name" value="Radical_SAM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical_SAM_N" evidence="6">
        <location>
            <begin position="26"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="255" mass="28557" checksum="80D5656B09F9EF5C" modified="2016-11-30" version="1">MNILDAKHIFSYRKYWAQRFGVAPELPMNRTEMDVLGWDSCDVILVTGDAYIDHPSFGMALIGRLLEEQGFRVGIISQPDWHSAEDFKRLGRPNLFFGVTGGNMDSMVNRYTSDKKIRSNDAYTANGEGGKRPDRAVNVYSHRCREAYKDIPIIIGGIEASLRRIAHYDYWSDKVKKSVLVDAKADLLVYGNAERQITEIAQRLAAGESIADLKGIRGTVHFVKQVPAGWTVKNSSDIDQPGLVIKPKNPLSDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQF1</accession>
    <name>A0A1D3RQF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_340680_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000989">
        <property type="protein sequence ID" value="SCN47779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="67" mass="7473" checksum="C29230232466A3C2" modified="2016-11-30" version="1">MTINPAEIIAASGNAFIETEEQVDRRAILPYEILGTPVTKYSLTYGANWISPSTPCVRFNFAQKPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQN5</accession>
    <name>A0A1D3RQN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP synthase beta chain</fullName>
            <ecNumber evidence="4">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_140222_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01001014">
        <property type="protein sequence ID" value="SCN47818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="78" mass="8892" checksum="C23517E684597652" modified="2016-11-30" version="1">MGMDELSEDDKLTVSRARKIQKFLSQPFQVAEVFTGSEGKYVPLVESISGFKKIMNGESSLYDRNNNTVERCVKVKWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQX8</accession>
    <name>A0A1D3RQX8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_12951_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="FMJP01001066">
        <property type="protein sequence ID" value="SCN47887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="492" mass="56241" checksum="1F49C4768D69B4DA" modified="2016-11-30" version="1">MTGINLLSQRRAGVLLHITSLPNNNGRGNLGKEAYHFVDFLHNAGIKVWQTLPLGVPHADGSPYQCLSAHAGNPALICLESLKQKGWLQETEQCDMCRADNSFDLHCLIAKAYTGFINLADSQEKQAYLDFCKDKASWLDDFSLFVALRNEFSGQSWSQWPQHLKERETKSITEARRRLGLAIEIIKFEQFIFYSQWMALKTYANERNVLLFGDIPIFVSYDSADVWANRRVFKLDENGEMLVVAGVPPDYFSVTGQRWGNPHYDWKYLKRTRFTWWKKRLESQLEMFDILRIDHFRGFEAAWEIPATEETAINGVWVEAPGKELLTALIKEFGNIPLVAEDLGIITAKVEALRTDFNLPGMKILQFAFGDTAANPYLPHNYERNYVVYTGTHDNDTTLGWFNALNDHDKQRIYHYLGYSQASMPYLLIGTAFSSVANLAIVPMQDILELGSADRMNTPGTTEGNWQWQFSWDQLTEDKVAKLTGLVTMFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL65</accession>
    <name>A0A1D3RL65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04471_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000015">
        <property type="protein sequence ID" value="SCN46406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4875" checksum="E1D9D76626DB2003" modified="2016-11-30" version="1">MRSEKIVHEKKKAFYGYYFFCFRWLDAQANLATLNNKKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM2</accession>
    <name>A0A1D3RLM2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3Beta_HSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_176832_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000119">
        <property type="protein sequence ID" value="SCN46544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003854">
        <property type="term" value="F:3-beta-hydroxy-delta5-steroid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3Beta_HSD" evidence="1">
        <location>
            <begin position="7"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5255" checksum="79510FAE1B7AD5EB" modified="2016-11-30" version="1">MSDSVVLVTGGSGCLGQHIVKHLQILGNDVKEIRVLDVVEYKQKLGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN9</accession>
    <name>A0A1D3RLN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thiazole synthase</fullName>
            <ecNumber evidence="4 6">2.8.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">thiG</name>
        <name evidence="8" type="ORF">BAZMOX_02676_2</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:26297"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12909"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer. Forms heterodimers with either ThiH or ThiS.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ThiG family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.10" evidence="4 6"/>
    <dbReference type="EMBL" id="FMJP01000161">
        <property type="protein sequence ID" value="SCN46591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990107">
        <property type="term" value="F:thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04728">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00443">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010035">
        <property type="entry name" value="Thi_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033983">
        <property type="entry name" value="Thiazole_synthase_ThiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008867">
        <property type="entry name" value="ThiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34266">
        <property type="entry name" value="PTHR34266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05690">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01683">
        <property type="entry name" value="thiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiG" evidence="7">
        <location>
            <begin position="72"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="254"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="276"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DXP" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="325" mass="34530" checksum="8BDE0AE72DC83512" modified="2016-11-30" version="1">MNVYVNGETKQYTENSTIADIVSELGLENKRIAVELNKEILPFNQYAQTTCQEGDYIEVVQAIGGGQGDSFTIAGQEFKSRLLVGTGKYKDLEESRLAIEASGAEIVTVAIRRTNIGQNPGEPNLLDVISPDKYTILPNTAGCFTADDAVRTCRLARELLGGHKLVKLEVLADQKTLLPDIIETLSAAELLVKDGFDIMVYTNDDPIIAKRLEDIGCVAVMPLAAPIGSGLGVQNSYNILTIVENANVPILVDAGVGTASDAAIAMELGCTGVLMNTAIAAAQNPVLMASAMKKGIQAGREAYLAGRMPRKRFASASSPLDGLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ6</accession>
    <name>A0A1D3RLQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsT</name>
        <name evidence="9" type="ORF">BAZMOX_15446_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000184">
        <property type="protein sequence ID" value="SCN46635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33398">
        <property type="entry name" value="PTHR33398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00029">
        <property type="entry name" value="S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="9546" checksum="C95FC4280F835CF8" modified="2016-11-30" version="1">MANSAQAKKRARQAEVSRIRNTGQRSNLRTFIKRVLAAVDSGDVEKATAAYTTVVPIIDSAVNKGLIHKNKAARNKSRLNKKIRAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR1</accession>
    <name>A0A1D3RLR1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_20757_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000047">
        <property type="protein sequence ID" value="SCN46448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041963">
        <property type="entry name" value="BsuBI/PstI_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041454">
        <property type="entry name" value="BsuBI/PstI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041962">
        <property type="entry name" value="BsuBI/PstI_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009528">
        <property type="entry name" value="Restrct_endonuc_II_BsuBI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011639">
        <property type="entry name" value="RM_methylase_Eco57I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06616">
        <property type="entry name" value="BsuBI_PstI_RE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17728">
        <property type="entry name" value="BsuBI_PstI_RE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07669">
        <property type="entry name" value="Eco57I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Eco57I" evidence="6">
        <location>
            <begin position="155"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="BsuBI_PstI_RE_N" evidence="7">
        <location>
            <begin position="519"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="BsuBI_PstI_RE" evidence="5">
        <location>
            <begin position="668"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="638"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="834" mass="95170" checksum="81311FF60948891F" modified="2016-11-30" version="1">MPEDKALFAFTNSCDRTKMIESAVLAQNEYFAVKPKAIRKELGQYFTGSMVADYMASLIVPVNAPVVRILDAGAGTGVLALAAALRCLELGHECVHAVLYEIDEEILSHLDLNMRRLSRTFQAQGAKFTFDIRHEDFVLARPDKAEELFHVSSINPPYFKYNSKTSPYACATTDLYKGNPNIYASFMAVVASCTAENGQMVAIVPRSFTNGLYFKGFRKYLNATMSLERIHIFRARNKVFKELSVLQENVICSYTKRRQSSKIVISASSGYEDIVQSERREYKTKLLIDCSNEHEIIRIPETAEDLQILETVEQWPSDFQNSGYTISTGRVVEHRTREYIIQPNKKAIAVPLLRMHNVKAFKTEWTGRCKKDASFLLLEGHQKHTSENIPYVILKRFSSKDEKRRLVAGVHNHKIIVGILIALENHLNYIGRVDSPIDIIECYGLAVLFNSTLMDKYFRCISGNTQVNATEIRLLKLPARKVICAMGKAVMDCSDTNQENIDQIVNDCIGVRGSMTKEEKLAQAQELLEMLGLPKQQYNNRSAWVFLALANIRPQDNWQDAQAPLLPTVDIMQFIREYYGQDYKPNSRETIRRQTLHQFEQARIVDRNRDNPSRATNSKDNNYSLNEPIIEVLREYPNGEWQAKIAEYEKELNNLQELYQRKLDKEKIPIRFANGQEIMLSPGKHNQLHADIVHEFCSRFIGNSGVVLYIGDTASSRNEGGKLMILETEQLKALGVSPMAHDKLPDVVVYDQERKWLFLIEAVTSHGAISPKRWIELEKALESCKVGRVYVTAFPDAAEFRKYAADIAWETEVWIADNPDHMIHFNGDRFLGPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR6</accession>
    <name>A0A1D3RLR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00589_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000166">
        <property type="protein sequence ID" value="SCN46603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="135" mass="15621" checksum="B652C3F80FA3EB93" modified="2016-11-30" version="1">MTIAVSLFRKDDKFYTQLLYGRPTKIVNRDNGKIALVSENELFLYETVVRKTNVYLFRGVGDISIPFVRPGVNLISHGNNIMQKNKLIKTLKWLEDHGYDPNQFDDDFWLRVQAIINSKSYGKKHLLSLLEKGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU6</accession>
    <name>A0A1D3RLU6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="9">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">alaS</name>
        <name evidence="11" type="ORF">BAZMOX_09988_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000196">
        <property type="protein sequence ID" value="SCN46651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="10">
        <location>
            <begin position="4"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="561"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="659"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="870" mass="95464" checksum="1701FFAB12497F94" modified="2016-11-30" version="1">MKNLTSAELRATFLKFFADRDHSIQPSSSLVPGNDPTLLFTNAGMVQFKDTFLGREPRNYVRAATSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKKEAIHFAWDFLTKELGIPAEKLWVTVFNEDSEAEKIWLEDVKIDATRFSRIGAKDNFWSMGDIGPCGPCTEIFYDHGEDIAGGPPGTPEEDGDRYIEIWNLVFMQYDRDTDGHLTPLPKPSVDTGMGLERIAAVLQGVHNNYEIDLFQKLLKVAADLAGTKDLTEGSLRVIADHIRSCAFMVVDGVMPSNEGRGYVLRRIIRRAIRHGYRLGIREVFFFQLVAPLVVEMGAAYPELAAAQEQVERILKLEEERFAETLEQGMKILEACVEKMHGTVIPGDVVFQLYDTYGFPVDLTADYARENGLSVDHAGFDIAMTAQRTRARAAKSFGDGYNQTIKLDAQTKFTGYQQLNEESKIIGLFQQSEAVSVLAEGTEGVVILENTPFYAESGGQAGDRGRIEVDGAVFEVTDTQKQGGSLFLHYGKVVSGELKNNLPCSAFVEPVSRQAIVLNHSATHLLHAALRQVLGDHVTQKGSLVNAERLRFDFAHFEPMTTEEIKIIERIVNQQIRHNAAVSADIMSKEDAINAGAMALFGEKYGDEVRVLKIGDFSTELCGGVHAKRAGDIGLFKIISETGVASGVRRIEAITGEVAMQWLEGREKSIAAISSVVKSSPEAIAEKVQQLMDKSKALEKELERLHVKLASSAGGELASQAVDIDGVKVLAVKLDGVEPKAMIDVLDQLKNKLISAAIVLATVKEGKVTLIAGVTKDQTARIKAGDLVNAVATQIGGKGGGRPDMARAGGTEPEKLEQVLQQVPEWVREQIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV2</accession>
    <name>A0A1D3RLV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_473573_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000046">
        <property type="protein sequence ID" value="SCN46447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="7"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5267" checksum="6FD16E6BC9F3E6A9" modified="2016-11-30" version="1">MGSTLEYQTVPELRSGLKRYFEFYNQERLHQSLGYKTPSEVHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX2</accession>
    <name>A0A1D3RLX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplI</name>
        <name evidence="11" type="ORF">BAZMOX_08412_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000063">
        <property type="protein sequence ID" value="SCN46467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="9">
        <location>
            <begin position="2"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L9_C" evidence="10">
        <location>
            <begin position="44"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="129" mass="13613" checksum="FF8FAECAFEAAC809" modified="2016-11-30" version="1">MKSGYARNFLIPQMKAVMATAKKIAEFEARRAELEKVAAEKLAAAQARAVALGKIEVIITHKAGDEGKLFGSVGTHDIADAMTAAGAAVNKSEVRLPTGIIRQVGDYDIDVNLHADVIATVNVQVVAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY2</accession>
    <name>A0A1D3RLY2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MobC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00432_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000065">
        <property type="protein sequence ID" value="SCN46477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008687">
        <property type="entry name" value="MobC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05713">
        <property type="entry name" value="MobC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MobC" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="111" mass="12553" checksum="49CE6019870C81F5" modified="2016-11-30" version="1">MINEAEKKTERIDVKVTPSFKNMLTVKYTAMNMKESEFIRSAIMNAQLNFKLSDKDIGTLIGTLGSIGNNVNQIAHNLNIAKKQNALNEVDYDDVTNQLLIIKEHLRNLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM13</accession>
    <name>A0A1D3RM13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_06146_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000227">
        <property type="protein sequence ID" value="SCN46706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="80" mass="8423" checksum="E46E412EC75E1762" modified="2016-11-30" version="1">MQAPKPAPDIFLQAAGSLEQDIQSCLVVEDSLIGLLAAKNANIFSVLVPSISVNECMQKSAGIILNDLSELSILVQAAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM14</accession>
    <name>A0A1D3RM14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_67306_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000256">
        <property type="protein sequence ID" value="SCN46745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="153" mass="17336" checksum="18E34BC4C66C1376" modified="2016-11-30" version="1">MDETYIKVKGKWVYLYRAVDSHGDTLDFMLSERRDEDAATAFFKQAINNNGFPDKVVMDKSEANYAGLANINLLLILAGFATMIDICQVKYLNNIIEQDHRFIKKITKPMMGFKAFHSAQATIAGIETAHMIRKGQLSEEYIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM22</accession>
    <name>A0A1D3RM22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_11336_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000123">
        <property type="protein sequence ID" value="SCN46548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="Mit_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="Mitochondrial_sb/sol_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="Mt_carrier_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="PTHR45635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="SSF103506"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="303" mass="33234" checksum="425CC33D6381940C" modified="2016-11-30" version="1">MSSQKLSFAENFALSGAAAVISKTAAAPIERIKLLVQNQDEMLKSGRLAEPYKGVIDCTARTYRTEGILPFWRGNMANCIRYFPTQALNFAFKDQIKMMFKSKKSDSYSLKFSKNIAAGGAAGAMSLCFVYSLDYCRTRLANDAKSGKKGGERQFNGMVDVYRKTIASDGIQGLYRGFVISCVGIVVYRGFYFGLFDTLKPILLGDSANVFLSFALGYVVTISAGLLSYPIDTIRRRMMMTSGEAVKYKGSIDCTRQIVTNEGFMSLMKGAGANILRGVAGAGVLAGFDKLQEVYIKWRVGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM35</accession>
    <name>A0A1D3RM35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase, synthetase subunit / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit</fullName>
            <ecNumber evidence="1">6.3.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03651_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.3.5.3" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000246">
        <property type="protein sequence ID" value="SCN46730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4848" checksum="D9AD99F6606FF584" modified="2016-11-30" version="1">MMPHPERCFRKIQNSWQPSDWKEDGAWLRMFRNARVWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM42</accession>
    <name>A0A1D3RM42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_145843_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000240">
        <property type="protein sequence ID" value="SCN46723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="57"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="210" mass="24305" checksum="78A5C05302E5EFD1" modified="2016-11-30" version="1">MISMLKENSVATRVEPIPFDPLHEINTGVEAYSVYENKGIKFGVVDYRDPETRKLHRFVTTVPVTTHPGTIAILYFKRWTIEKTFNNTKSDFKETKAWSSNNNSLKNQMRLTAMSYNLMRVFEEISKIQQPELIQPSDKKYNETLEKRQQLAQKQDCFVNPLFFQARITRISSYTIRAVQNAILTGTSLHSFMSSLVARLVPRVELIGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM54</accession>
    <name>A0A1D3RM54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent Clp protease ATP-binding subunit ClpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11087_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000268">
        <property type="protein sequence ID" value="SCN46762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpB_D2-small" evidence="1">
        <location>
            <begin position="25"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="127" mass="14480" checksum="2DE555B8D05C20DF" modified="2016-11-30" version="1">MRVVEKTFSPEFRNRLDSIIQFKPLDIAVVGSVVDKFIFELETLLLEKNVTFSLDPEARLWLAENGCDPKMGARPMARLIQEKIKKPLANDLLFGKLERGGHVHVIVQDKELAFTIESKELSISEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM58</accession>
    <name>A0A1D3RM58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_196314_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000187">
        <property type="protein sequence ID" value="SCN46639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="4875" checksum="273A91CCC37428D3" modified="2016-11-30" version="1">MSSQYKQIGNAVPVNLSHAIGRSLVGLLNNITEHEANNQKITELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM60</accession>
    <name>A0A1D3RM60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Molybdenum cofactor biosynthesis protein MoaE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_172134_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000255">
        <property type="protein sequence ID" value="SCN46743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="80" mass="9233" checksum="5BEE9016B3693EBE" modified="2016-11-30" version="1">MQEAERQWSILDVLVIHRVGDVFLDDVLVLVVVWSGHRGGAFDASRFIMETLKSKVPFWKKEILADDKSRWVAKNTDGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM63</accession>
    <name>A0A1D3RM63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_47261_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000165">
        <property type="protein sequence ID" value="SCN46598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4323" checksum="08CDB485DDA540A2" modified="2016-11-30" version="1">MIVCDCSAYQNQKNIESNLFFSRTGGDSMLIQMTDTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM79</accession>
    <name>A0A1D3RM79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonuclease E</fullName>
            <ecNumber evidence="7">3.1.26.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_11087_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.1.26.12" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000268">
        <property type="protein sequence ID" value="SCN46764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="324"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="402" mass="45496" checksum="6576CC3A80802681" modified="2016-11-30" version="1">MLANKNQRAVENRMRDALKIDRARVQTSRISRFGLLEMSRQRLRPSLGDTTQLTCPRCNGQGEIRNVESVALSVLRILEEEAMKGGTDRVIAHLPIECATFLLNEKRPSIDQIESRLKVRIIILPSKHLETPAYDIERIKLKDEDGSTETTSYSQIQHEEITAPDFAKEAAPKIEQAALKEFLPDAPAPPIQTIQNKKNSASLISRFWNKLVGPAEEESADQPASTNDTKTEKTRTERPQNNRNRNNNPRNRSRNNNRDRRNKPNTGKSTDTNVTATTKPQERKEEPVIETNGVANSEAKPRNQQKRTNRRNHNRKPREKTEGTQSNTGKSNNSTENKNLTQSEPVTQEKRNTNTQSYAADYQKNITTNKTEIAVPAPTEKKESSTPSKEVSTIVETVKEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM87</accession>
    <name>A0A1D3RM87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_13356_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000290">
        <property type="protein sequence ID" value="SCN46792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="49" mass="6002" checksum="9C278F5E18B0E257" modified="2016-11-30" version="1">MVFFNFIFHYLPKLPNKIRVKNLFISEKSIKREFIVQDRLHSAYKKFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-06-17" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD1</accession>
    <name>A0A1D3RMD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type IV pilus biogenesis protein PilM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_202211_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000306">
        <property type="protein sequence ID" value="SCN46814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005883">
        <property type="entry name" value="PilM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11104">
        <property type="entry name" value="PilM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01175">
        <property type="entry name" value="pilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="286" mass="31654" checksum="F9647B74E87AD2BF" modified="2016-11-30" version="1">MKWLNRKHDHLLGIDISSAAIKLLELSKTGGRYKVESYAVAPLAPDAVIDNNIFNAEMIAETIKAAIKHSGTRTRHACVAISGSSVMTKMITMSAHLSEDEMEEQIMVEADQYIPYSLDEVRLDFEVQKVNEANPELVDVLLAASRRENVDERVDVLTQAGLTASIIDVEAFAMENAFALLSDQLPNSEHEQTVAIADIGATMTTLNILHKGRAIYTREQGFGGKQLTEEIQRRYGLSYEEAGLAKRHGGLPDNYNSDVLGPFKRALVQQVARSLQFFIRLVPIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF7</accession>
    <name>A0A1D3RMF7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lspA</name>
        <name evidence="9" type="ORF">BAZMOX_11241_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6 7">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the peptidase A8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000348">
        <property type="protein sequence ID" value="SCN46885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00855">
        <property type="entry name" value="SPASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="17439" checksum="FC887E7268BD7F13" modified="2016-11-30" version="1">MMKWLWLSGLILILDQLSKIWINISMNLYQSIPVFPGFSITYAHNYGAAFSFLSDAGGWQRWFFAALAAGISIGLVIYLKSLKQDETLLAVSLSLILGGAIGNLIDRVIYGYVIDFLDVYYQAYHWPVFNIADSAITIGVAFMLYESLVVKDKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI2</accession>
    <name>A0A1D3RMI2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxoglutarate dehydrogenase (succinyl-transferring)</fullName>
            <ecNumber evidence="2">1.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_25028_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000235">
        <property type="protein sequence ID" value="SCN46718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="5">
        <location>
            <begin position="226"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="571" mass="64739" checksum="FA12BD90E8FD6F41" modified="2016-11-30" version="1">METLNMAQTRAFATGGTIHVVINNQIGFTTSNPFDARSTLYCTDVANMIQAPVFHVNGNDPEAVLFVTQMALDYRSTFNKDVVIDLICYRRRGHNEADEPATTQPMMYKKINALPTTRALYAAELIKKNILTEQQTQDIEQAYQDLLDTGQPVSRPMLESGYSYSKLWDKYVNQDWDTPCDTHVPLERIRFCNNQSQRLPPEFELHPRVSKIMDNRRKMAAGATPLDWGFAENMAYATLLMDKKNVRLVGQDVGRGTFFHRHIILHNQINGDSYIPIKHLDIDQGRVQVFDSILSEAGVLGFEYGYSSTVPETLVIWEAQFGDFANGAQVVIDQFISSGESKWGRLSGLVMLLPHGLEGQGPEHSSARLERYLQLSADQNMQVCVPSTPAQIFHLLRRQALRTYRKPLIVMSPKSLLRHKHAVSTLEDLVDGHFKTIISETNVSIIAEKVTRLVLCSGKVYYDLIEAREHNNPNNVAIIRIEQLYPFPTANFQAEFTKYPNLTTLVWCQEEAQNQGAWYQSRHNFTQFKPEHIELTYCGRPASSSPAVGSLAKHLEQQKEVVEKALYGHSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ1</accession>
    <name>A0A1D3RMJ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0178 protein BAZMOX_180737_1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_180737_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0178 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000363">
        <property type="protein sequence ID" value="SCN46911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00489">
        <property type="entry name" value="UPF0178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003791">
        <property type="entry name" value="UPF0178"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35146">
        <property type="entry name" value="PTHR35146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02639">
        <property type="entry name" value="DUF188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="149" mass="16662" checksum="54A330FE78E35FBD" modified="2016-11-30" version="1">MNIWVDADACPVAIKDILCRAAERTQVQVTFVANQFIRIPPSRYIVFIQVPPGFDVADNEIVNRLSAGDLVITGDIPLAAEVVEKGAYGLNHRGELYTENNIRESLNIRDFMDTLRSSGVSTQGPRTLSVSDRQDFANHLDKFLSQRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ4</accession>
    <name>A0A1D3RMJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_05516_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000279">
        <property type="protein sequence ID" value="SCN46779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025500">
        <property type="entry name" value="DUF4390"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14334">
        <property type="entry name" value="DUF4390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="123" mass="14370" checksum="5A95C1966B74DC27" modified="2016-11-30" version="1">MDGFYYARLQKNKALLLALFVLLSSLSGRGYADDRFVKIEQAQLTLAENKAQLRADVTFQLSQSAQDALHSGIALYWDVTIELKQVRWGGLWQSVLFSRSRRYRLAYYTLLNNYRVKDEKKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ7</accession>
    <name>A0A1D3RMJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
            <ecNumber evidence="10">6.1.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_11241_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="10"/>
    <dbReference type="EMBL" id="FMJP01000348">
        <property type="protein sequence ID" value="SCN46884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="7">
        <location>
            <begin position="3"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="9">
        <location>
            <begin position="260"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="zf-FPG_IleRS" evidence="8">
        <location>
            <begin position="473"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="512" mass="58216" checksum="A7F4018EDE3D37DC" modified="2016-11-30" version="1">MEQAELRKKALAEIKKVQWLPEWGQARIEGMIENRPDWCISRQRTWGVPIPFFVHKETGALHPETDKLVEDIALHVEQKGIEAWFALDKAEWLGAEAEQYEKMQDTLDVWFDSGVTHEAVLNQREQLRFPADLYLEGSDQHRGWFQSSLLTSVAMNGVAPYKTVLTHGFAVDAEGKKMSKSRGNVVAPQTVMKSLGADVLRLWVSGTDYRGEMTVSDEILKRTADVYRRLRNTSRFLLSNLDGFDPKLHSVDAKDMLALDRWIVDRAFNLQEEVKQAYDQFQFHVINQKVHHFCAMDLGGFYLDIIKDRQYTAKADGLARRSAQTAMYHVMEALVRWLAPITCYTADEIWQYMPGERSESVLLETWYEGLFALNDDALMSNADWECVMSVREAVSKELEKMRKSGVIGASLNAEVTLFCDAEYTAVLKKIAEELHFVFITSQAVVLPIQDAGSDAEITELEGLKVKVVASEHEKCVRCWHYKADVGSHAEHPELCGRCVDNIAGDGEVRQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML1</accession>
    <name>A0A1D3RML1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_107087_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000384">
        <property type="protein sequence ID" value="SCN46935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5320" checksum="A39585026B4AF449" modified="2016-11-30" version="1">MPEDKACFVFTNICDRTDFKLQLIYLDGFSSVFINFKVKLLQSGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML6</accession>
    <name>A0A1D3RML6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_161123_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000369">
        <property type="protein sequence ID" value="SCN46920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920233" evidence="1">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="219" mass="24824" checksum="3DB6B67B0A17E545" modified="2016-11-30" version="1">MKKLLLVFALTMILPMQANARVREYSFTPSIPVLEDKSSDGWIAGQVDQVSFDYKLPCDPSLSPYSAIVVQGFERMDLLTRNEDGERDVSIAYPRMAEFCVVIAMPKSGIVTNEDYKAEKRRTWWLTEGTVDRYGYTIRDEDEEIAATINLLKLAKQALGKPTYIVIGNDSGVLAEKVIMKLDETNEVNIIAGFIYVDKDTGEFTLYNSDQTKWESKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM2</accession>
    <name>A0A1D3RMM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid replication initiator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_26985_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000365">
        <property type="protein sequence ID" value="SCN46913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018777">
        <property type="entry name" value="Replication_initiator_prot_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10134">
        <property type="entry name" value="RPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="351" mass="40045" checksum="D87E2D240173524B" modified="2016-11-30" version="1">MTKQIDEDGSSRKPTKGKVIEREIKNSSFDSDNCITYSELERAASEVKDSRLAARLKKLSRNYRRAPEGDQQMSLFEPTLMDVSTKDDISLMDVAVFGLGRKPRFEPIEHDLKDAHITIQGGTKCGMATIFDYDIFLYMVSYLTHEMNVVRRAAENGQDSYLPPRKIKPSVVELLKYCRRDLGGKNYKMLESALIRLDNTNILISHKNSKSRRSGSFNLIDGYEITSETKTGKISEVSINIPSWVYDGVVRNGDPRVLTMPKDYFLLDQGNHRFLHRLCRKAAGKGEANYNLQTIYERSGSTSPFRSWKSKFKKSIETLGIKGKALPDYLVIWDKKENGRINIKMVFTGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR3</accession>
    <name>A0A1D3RMR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TRAG protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01638_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000388">
        <property type="protein sequence ID" value="SCN46944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="86" mass="10014" checksum="6D0B7FB567FEDFC1" modified="2016-11-30" version="1">MIITLGVWGATQYCAYELGHQENLGDPWFILFGYPVYIPWRVFEWTYYYEVYAKGVFATSYLFIYGSFAIEASFTGLYCGLEGKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS4</accession>
    <name>A0A1D3RMS4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="3 6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recG</name>
        <name evidence="9" type="ORF">BAZMOX_00824_3</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 6"/>
    <dbReference type="EMBL" id="FMJP01000397">
        <property type="protein sequence ID" value="SCN46954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004609">
        <property type="entry name" value="ATP-dep_DNA_helicase_RecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00643">
        <property type="entry name" value="recG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="287"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="485"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="696" mass="77659" checksum="4311CA73EE3AEC34" modified="2016-11-30" version="1">MDSQDTLNQSVASLKGIGGQSVVRLEKLDIRRIRDLIFHLPLRYEDRTHIQAINSLNPGSHALICARVISSTILDRGRRSLVCQITDDTGYLSLRFFHFSASQHNNLSPGTLLSCFGEIKDGYSGYEMIHPEYKIIKNPEDCITNDTLSAIYPLTEGLRQSSIRKAVQQALTLYNNNTEALPDLLPSALLNRYNYPSLDQALNTLHMPAAGVSVDTLQNSQNPALTRLAFEEFIAHQLSQLHKKKSEQHWQAPLLKSTQQQSKQFLDGLPFQLTKAQQRVIQEIKADCSKNSPMLRLVQGDVGSGKTVVSAYAALLALSSNYQIAIMAPTELLAEQHLRNFSQWFKSFDTQIIYLTGQLKGKKREHALTAINDGSAGLIIGTHALFQDAVNFARLGLIIIDEQHRFGVNQRMALRDKGHNNNSKPHQLIMTATPIPRTLAMLNYADLDISIIDELPPGRIPVVTRAIASERRPEIIAKITNWVKQGRQAYWVCTLIEESEVLQCEAAEDTATMLAEMLPHVRIGLVHGRMKATEKDQVMQAFKAHKLDLLVATTVIEVGVDVPNAGLMIIENPERLGLSQLHQLRGRVGRGSEDSFCILMYQSPLSKTAGERLNILRETSDGFLIAEKDLELRGPGEMMGTKQTGQLQFKIANLERDATLLEDVSAAVKIIQETCPENIQPLIERWLGTTTKYAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV0</accession>
    <name>A0A1D3RMV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_28787_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000287">
        <property type="protein sequence ID" value="SCN46787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="126" mass="13653" checksum="81C291ACE8505DAB" modified="2016-11-30" version="1">MSVNDLNALLQVAVELIIILGFSNLALSIAKKRQRFVQTTCALLGTDALISLCAAPVIATLSISPNNGLALLAIISLIIWHWLITAHIIRHALSQSFSFALGIAFLYIFSAYQIMGVLFPTMNPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW0</accession>
    <name>A0A1D3RMW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_158934_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000466">
        <property type="protein sequence ID" value="SCN47045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021409">
        <property type="entry name" value="DUF3047"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11249">
        <property type="entry name" value="DUF3047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="184" mass="21539" checksum="D8FD54F8B9F9919E" modified="2016-11-30" version="1">MQLNDWQHKSFKGETQYQIILLDKQAALQAKSRASASSLYKEIHIDLHETPYLNWSWRIDKKLAINNEQSKQGDDFAARIYLISKNKWFFWQSKAINYVWANNTAKNTVWPNPFAGKNVMMFAIRSGDNPTKQWHTEKRNVLNDLKNIFGEDIRYIDAIAIMTDTDNSSGRADSYYANLYFSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX8</accession>
    <name>A0A1D3RMX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RepA protein-Haloarcula marismortui</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_95336_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000362">
        <property type="protein sequence ID" value="SCN46909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="3"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="252" mass="29562" checksum="DF4A69AE0C5883BA" modified="2016-11-30" version="1">MDISEQRIILACLGQCNPLELTEKTVVHISVNTIMDLADTSSKSAYEELKRASERLFNRQVVIDNPDPDDPTLTRTRTRWVSSINYYDGEGRISLHFSTRIIPYLSQLQGKFTKYKLQHVTQFKSSYGVRLYELLLQWQSKGTREIEIDWLRKTWGLETKYKALKDLKKWVIEPAMKDINKHSNLWVKFGQRKAGRRVVEFKFQFGLKKPGQAPKKLTQKQAEALARTGESYKNLYERLKYEGYQLDIKKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY9</accession>
    <name>A0A1D3RMY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division protein FtsH</fullName>
            <ecNumber evidence="4">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_04671_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.4.24.-" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000446">
        <property type="protein sequence ID" value="SCN47014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_lid_3" evidence="3">
        <location>
            <begin position="2"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M41" evidence="2">
        <location>
            <begin position="56"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="293" mass="32527" checksum="FD4E1B04A3CDA8C0" modified="2016-11-30" version="1">MKYIAQGTPGFSGADLANLVNEAALYAARMNKRLVSMIDLERAKDKLIMGAEKRSMVMDEKEKKMTAYHEAGHAIVGKIVPEHDPVYKVSIMPRGRALGVTMFLPEKDQYSASKCKLDSMISSLYGGRVAETQIFGWEQVSTGASNDIERATELARNMVTKWGLSQRLGPLAYSEEEGEVFLGRSVTQHKSVADETSHTIDEEIRSIIDKNYARAEQILKDNEDILHAMADALMKYETIDKEQISDLMARKPVRAPKGWDDDPTPPNKSVKIDTSVDKKGGTDKSIGNTAEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN20</accession>
    <name>A0A1D3RN20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cobalt-precorrin-2 C20-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.130</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_39746_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.130" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000485">
        <property type="protein sequence ID" value="SCN47072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030788">
        <property type="term" value="F:precorrin-2 C20-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11645">
        <property type="entry name" value="Precorrin_2_C20_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012382">
        <property type="entry name" value="CobI/CbiL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006364">
        <property type="entry name" value="CobI/CbiL/CobIJ_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036427">
        <property type="entry name" value="Precrrn-2_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01467">
        <property type="entry name" value="cobI_cbiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="249" mass="27547" checksum="4CA63AA3699155F2" modified="2016-11-30" version="1">MIGTLYGVSLGPGDPELMTRRAWALLHSEADWTYPVKRKQGESYALKIALAANLKVPENSTELVFPMTHDREILAKYWLQAAQIVLEKLQAGRDVIFLVEGDASTYSTFQHLAKTVAGLDETATIETIAGVSSFHAAAARAKMPLADTDDTVAIIPAGYGIEMIEAMLLDFDTLVLLKVKPLLDDIISLLERKGLLAQSCFIEKAGSNEERIIHDVLSLRGEKVNYLSLLMVHNSHRMRGELIRGCRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN23</accession>
    <name>A0A1D3RN23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication initiation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_241998_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gram-positive plasmids replication protein type 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000491">
        <property type="protein sequence ID" value="SCN47080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000989">
        <property type="entry name" value="Rep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01446">
        <property type="entry name" value="Rep_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="133" mass="15603" checksum="EE73DFBB989C473C" modified="2016-11-30" version="1">MKRQQPLIEIWQSCLRGDYAPGVNIKVVKPKDKNIKAGSAEFLRSAVKETLKYSVKPSDMTEQDPSWFLELTKQTGRKRMIATGGVLKNVLRVDDESNEDFILLSEDEEQEQEQEQDIELFFKYQKRHYYRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN25</accession>
    <name>A0A1D3RN25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cobalt-precorrin-6y C5-methyltransferase / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating]</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_39746_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000485">
        <property type="protein sequence ID" value="SCN47073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014008">
        <property type="entry name" value="Cbl_synth_MTase_CbiT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02469">
        <property type="entry name" value="CbiT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="3">
        <location>
            <begin position="152"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="316" mass="34703" checksum="F77C55D97219578C" modified="2016-11-30" version="1">MAFARIGMAWQDAKICSVHSKDAGEWYRGAAAEHGLYALLQAINQHDKLAILTSPENNPARIARMLMIENMANLFNMVVAEDLLCTDEKLFQGLSIAELAEQEFTGNDVVILCRVQEKADALLFGYADHAFKQRKPDKGLITKREVRAVSLARLQLTINSIVWDIGAGSGSVGIEAAKLCIQGHVYAVEKNAADFAIARENARNFGLHNYTLIENKAPLGMQDWPEPNAIFIGGSGGELAGLIELCLAKLQANGCLVMNFVTLENLNTALETLKQSDALWDITQLQASRSQPILHMNRMQAENPVWIVCAQKEIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN64</accession>
    <name>A0A1D3RN64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_97592_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000515">
        <property type="protein sequence ID" value="SCN47103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5580" checksum="DAFE71926BE4DBD3" modified="2016-11-30" version="1">MEAVKGRGYRGDIAIDDVKYTSGQRCPQSMYIGIRCFEINYSIRFKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN75</accession>
    <name>A0A1D3RN75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat shock protein 60 family chaperone GroEL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_109183_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000542">
        <property type="protein sequence ID" value="SCN47140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="90" mass="10051" checksum="21168E46E0A2968A" modified="2016-11-30" version="1">MNEKKDRVNDALNATKAAVEEGIVPGGGVALLRCVSVLDGVKTENEDQKTGIILPLKIKLTEFCMIVVSHWIYFPVDTMIQRKIGYELKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN81</accession>
    <name>A0A1D3RN81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_20759_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000529">
        <property type="protein sequence ID" value="SCN47123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4280" checksum="BEA58018649B9023" modified="2016-11-30" version="1">MARLAQATITGIETAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN85</accession>
    <name>A0A1D3RN85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Similar to Polyserase-2 (Polyserine protease-2)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_334587_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000553">
        <property type="protein sequence ID" value="SCN47150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="122"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="207" mass="22735" checksum="33AF2DE1E4A30865" modified="2016-11-30" version="1">MGPYQAKDLSWDGTVNKVRELDLTRISNSLCSKNEKMSGRYGKDWITDNMICAGQGLGKKETCDGASGGPLIIFNGRTNTWMHSGVSSFGGGCAPYGVYARTSKITRWVSDLMCSNEEVPDIPSSLKSSDNGDKTATIKWSSVSGATGYHVNYWRKNDGSDKSTLDLKENSFTTPKEASGRSFYVTVNSYKNNCLSKETKEKYITLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB5</accession>
    <name>A0A1D3RNB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="7" type="ORF">BAZMOX_00289_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000434">
        <property type="protein sequence ID" value="SCN46998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="30"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="307" mass="34349" checksum="460ACB5923744A33" modified="2016-11-30" version="1">MHLPVLYSETLRELTIKPSGIYIDCTFGRGGHSKGLLQQLGPEGKLLALDRDLDAINSDTAQELFKDPRFELEHCCFSRLQNVVEKRGWMGKVDGILMDFGVSSPQLDNAERGFSFMQDGPLDMRMDCSSGLSAAEWLASVSEQDLVRVLYDYGEERFARRIAAAIVAQRLEAPLVTTKQFVDLLVAVIPFREKHKHPATRSFQAVRIAVNHELDEISAVLGQAVNVLASGGRLVVISFHSLEDRIVKRFIRDESRGKYNPVKLPMQADELAAIRLIKCGKAIKAEAEELARNTRARSAIMRVAERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB7</accession>
    <name>A0A1D3RNB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsN</name>
        <name evidence="5" type="ORF">BAZMOX_10545_6</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000565">
        <property type="protein sequence ID" value="SCN47172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00537">
        <property type="entry name" value="Ribosomal_S14_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023036">
        <property type="entry name" value="Ribosomal_S14_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="101" mass="11522" checksum="EC673DA0FA78AC52" modified="2016-11-30" version="1">MAKKSMIAREAKRVKLVSKFEVKRASLKEIIRDPNASIQDKDEAHLALQKLPRDSSASRVRNRCNITGRPHGFYRKFGLSRNMLRQATMRGDVPGLTKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC6</accession>
    <name>A0A1D3RNC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_28918_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000410">
        <property type="protein sequence ID" value="SCN46967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="10520" checksum="1130F3F3346AE938" modified="2016-11-30" version="1">MSKAKAKNKIKTKGKATSKNVVLPGPMRMVWGALAAYWLRDIIHPAFTLIAVMILLMIPVLIANMFFPQPKPVVHDDAGDDVSVEDSEQEDAAEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND3</accession>
    <name>A0A1D3RND3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_44336_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000586">
        <property type="protein sequence ID" value="SCN47215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5147" checksum="50943AD0DDB3702C" modified="2016-11-30" version="1">MANFPVAYCGLKIITSLSLRFPDFQRVSIDHWKFHVANGAYRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND6</accession>
    <name>A0A1D3RND6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Predicted ATPase related to phosphate starvation-inducible protein PhoH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_23113_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000423">
        <property type="protein sequence ID" value="SCN46977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="3">
        <location>
            <begin position="8"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="471" mass="52763" checksum="C342A527BAF93861" modified="2016-11-30" version="1">MNISANKKLFVLDTNVLMHDPAALFHFQEHNIFIPMIVLEELDHAKRGVTEVARNVRQVSRFIDDLLKGTDKNDIKEGLALSQLQSSGQKENALDGRLFFQTQHMTSELPASMPGSLADNSILSIVLALSKEYPNTQVILVSKDINMRIKAAALEIKAEDYHSDQTLDDIDLLYSGSTALPEDFWETHGSKMESWVEDGHTYYKLAGPLVAGWFPSQYLYIENGSDSDFEAIVRSIDNDTATLELAKNYREGHHMTWGINAKNREQNFAINVLMDPEIDFVTLLGTAGTGKTLLALAAGLAQTMDDKTYKEIIMTRETVPVGEDIGFLPGTEEEKMTPWMGALIDNLELLGDQTENSDWEQNVTKTIVMNKFKIRSLNFMRGRTFLGRYLIIDEAQNLTPKQMKTLITRAGPGTKIVCIGNLSQIDTPYLTATSSGLTYVVDKFKSWEHAAHITLKRGERSRLADHASEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG2</accession>
    <name>A0A1D3RNG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_104487_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000584">
        <property type="protein sequence ID" value="SCN47212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="94" mass="11294" checksum="05AE3B9467F759ED" modified="2016-11-30" version="1">MEITPLSDFQIAETQTFQKAKTKLDDKLYKKITNIAYPQLRINPFFGHNIKKLKGEFEGVYRYRFGNYRLFYTIEKEKIIVAILDIKHRQKAYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH8</accession>
    <name>A0A1D3RNH8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ilvD</name>
        <name evidence="16" type="ORF">BAZMOX_00271_3</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="FMJP01000628">
        <property type="protein sequence ID" value="SCN47265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="476"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SCN47265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="561" mass="59213" checksum="FA6B4F50440B9DD6" modified="2016-11-30" version="1">MANDKNTRTFSSQVVDGMERAPSRAMLHAVGFKNEDFKKPQIGIASTWSMVTPCNMHINKLADNAAQGVNDANGKAVIFNTITISDGISMGTEGMKYSLVSREVIADSIETVTGCQGFDGVVTIGGCDKNMPGCMIAISRLNRPAIFVYGGTILPGCHKEKKLDVVSVFEAVGARANNQIDDAELAAIEEKAIPGAGSCGGMYTANTMASAIEAMGMSLPGSSAQAAVSDEKRKDCERAGAAVLELLKNDIKPSDIMTKAAFENAITVIIALGGSTNAVLHMLAMANAANVDIKLDDFTRIGAKVPMVADLKPSGRYQMAELIEIGGIQPLMKILLERGLLHGDCLTVTGKTLAENLANVKPYPIDQDMILPLNHPIKKDSHLVILYGNLAAQGSVAKITGKEGLHFTGTAKVFDAEEQALQGILNGDIVKGDVIVIRYEGPKGGPGMREMLSPTSAIMGKGLGKDVALITDGRFSGGTHGFVVGHITPEAHVGGTLAIIENGDKITINAETKKLTLHVDDTEISARLAKWQQPAPKYTRGVLAKYAKLVNSASEGAVTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK6</accession>
    <name>A0A1D3RNK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_112116_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000469">
        <property type="protein sequence ID" value="SCN47047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="247" mass="28228" checksum="C94884EDEA203AE0" modified="2016-11-30" version="1">MKTEAEETYANGRTLENAKEVVRQMKSDADKEYHNGVAKRTELRQWPNATAAANRIQGRYDHHEAIRVKARYGYSRYKHAYGSCWWGGVCLDHESASELWATMRNTVGLDIAPAKARIKPSGTTMGTELARTKLHLIWAMREKQRALTTQATVKNTFNTTRYNPVAYRTVNTANAEITWAEKSVKNALNEIKMVSGEVLERARQAKYSAAVDYFNEQKAIYYAEQEEVEMANINLMTVLLIINRRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK9</accession>
    <name>A0A1D3RNK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetraacyldisaccharide 4'-kinase</fullName>
            <ecNumber evidence="3">2.7.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Lipid A 4'-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BAZMOX_66689_0</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.130" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000618">
        <property type="protein sequence ID" value="SCN47253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009029">
        <property type="term" value="F:tetraacyldisaccharide 4'-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003758">
        <property type="entry name" value="LpxK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02606">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="5133" checksum="70CC503338CB3E77" modified="2016-11-30" version="1">MTEKDAVKCVDIATEQHWYVPVQAKLESGFTNNLTTLLRKVQGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL2</accession>
    <name>A0A1D3RNL2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2760 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00271_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000628">
        <property type="protein sequence ID" value="SCN47262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021212">
        <property type="entry name" value="DUF2760"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10816">
        <property type="entry name" value="DUF2760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2760" evidence="2">
        <location>
            <begin position="109"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="232" mass="25646" checksum="0EE99654392743B0" modified="2016-11-30" version="1">MNTQFKIDLDLIPTTFDAIHVYLAATVFGLALTVIILLFVLLMSAIRKAKKPEQKAVDNKEQAILTKIPKREPEVKIVEKIVEVEKIVEVEKIVQQPAPEPIVLKEATPDAALQLLSLLQTEARFIDFIKEDVNAYSDQDIGAAARVVHTGCHKVIKEHFTLTTIRTEQEGSKITLNKGFNASEVRLTGNIVGQAPFTGTLVHKGWKVTEVKLPKLTQGHNANIIAAAEVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM1</accession>
    <name>A0A1D3RNM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Electron transport complex protein RnfA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_36003_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000660">
        <property type="protein sequence ID" value="SCN47315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011293">
        <property type="entry name" value="Ion_transpt_RnfA/RsxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01943">
        <property type="entry name" value="rnfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="196" mass="21002" checksum="CB97D4E987C6693A" modified="2016-11-30" version="1">MNPESLSFIFLSAFLINNFVLAMFLGLCPFVGVSAKRDTAFNMSLATTFVMFVSSTCSYGINQILIAFDLEFLRLISYIALIASSVQLVEMILKKFSPALFRALGIFLPLITTNCAILGVALFQTSREYDFLQSVSFSLGAGAGFGLAIVLMAGLREKLELSNLPNITQAAALSMMLAGILSLTFMGFAGLGGSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN5</accession>
    <name>A0A1D3RNN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transaldolase</fullName>
            <ecNumber evidence="1">2.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_11998_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.2.1.2" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000489">
        <property type="protein sequence ID" value="SCN47077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4831" checksum="ADFA142E20FFE4D1" modified="2016-11-30" version="1">MVFLIFNYKRCQYMANLLDQLKAVTVAVADTGDIAAIEKIHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP3</accession>
    <name>A0A1D3RNP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ORF">BAZMOX_10545_3</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000565">
        <property type="protein sequence ID" value="SCN47169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="122" mass="13412" checksum="30DF82AAAC41DD82" modified="2016-11-30" version="1">MIQMQTNLDVADNSGAKKVMCIKVLGGSHRRYAAIGDIIKVSIKDAIPRGRVKKGEVYNALVVRTKNGVRRSDGSLIRFDGNAAVILNANHQPLGTRIFGPVTRELRNEKFMKIISLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNR4</accession>
    <name>A0A1D3RNR4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RHH_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_378050_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000658">
        <property type="protein sequence ID" value="SCN47313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="83" mass="9476" checksum="AA3C82F8F03268F7" modified="2016-11-30" version="1">MATEAFTVRAESNIIHQLDHIAGSLDRSRNYLVNQAIQEYLEAHAWQIEKITQGIEAADRGEIVEHDQVMQEMDALIDQKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS0</accession>
    <name>A0A1D3RNS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ADP-heptose--lipooligosaccharide heptosyltransferase II</fullName>
            <ecNumber evidence="2">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03110_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.4.1.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000634">
        <property type="protein sequence ID" value="SCN47286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="311" mass="35487" checksum="74689380458F4F42" modified="2016-11-30" version="1">MNVLVTRHDKIGDFITVLPLLKILKYNTNNRVIVMVSKINYDLACSINYIDDVILYSDNLYKNISEIKNRKIDVSISCFIDNKLGVTLFLSHIKTRISPATKLAQFFFNKTIKQKRSKVEKTEWQYNIGLLKLLDPDINCLFDRPLLFVQPDKAEIKQKIIAFHPGFGGSSEGNLKLDDYLRLAKSIAKKENVKVIFTFGPDDADSKQYIENNIDFTAELIDSKRSLVDFCKLISSCAVFVSTSTGPMHLAGALNIKTLSFFGNTLFASSKRWATISDKEKQANFEVPKNYDETFYLKVEKQLNNIVSEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT4</accession>
    <name>A0A1D3RNT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_319239_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000672">
        <property type="protein sequence ID" value="SCN47333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="108" mass="12571" checksum="CFD9638BDE7993F4" modified="2016-11-30" version="1">MEWSIEYYSPEVEESILGLPEGLLSRYFRLTDLMIEFGSNLGMPHTKPIENGLFELRVKSKEGIARAFFCTKVGKRIIMLHVFIKKTQKIPKKELVIANKRMLEVIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT7</accession>
    <name>A0A1D3RNT7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rep_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_106711_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000530">
        <property type="protein sequence ID" value="SCN47127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="32"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="360" mass="42605" checksum="A6CEC91D6BD5EBEC" modified="2016-11-30" version="1">MERCLFIEIYDTIKNFFMAESDANIVEYGSTHIKIKIPVKEIKQKFFKGGNKRRQLLDVAESLSKKQISMISVENDGQYGFDFITMFPRISYNPAVNKNDMYVEIHSGVYEEMVPIESYCQLDLKLLGEFNSGNTIRLYEIFKSYAFRNSFDITFNELRKKLGFFKEGSYQEWKHFNSQVLKPAVNNINSFKEYDIEVFYEKPRGLDKIEFKIKTHKVHDVRKINVLNLNESIDPAARTPNLIQQKYINTVISFCKSKTKITNEVELMDWIISDLINQQQKSEKQTDFKRMMNEISQQIRMDIYTQPYSHKHLVIDEIYFDPVIYKEIKKMEREGLHDSIKDQYSSEQIRANNFGFILDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT9</accession>
    <name>A0A1D3RNT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_05066_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0382 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000684">
        <property type="protein sequence ID" value="SCN47350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="PTHR43461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="126" mass="13543" checksum="25C891E7A398A66E" modified="2016-11-30" version="1">MHPVTLFLSALCAFIAVAMGAFGAHGLKTILTPDMLAVYKTAVTYQMWHALGLGLIALLRAQNPDVNLLKYAAWAMFSGIVLFSGSLYLLSLSGLKWLGMITPLGGLCFLAAWGLVMVVSFKSFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV3</accession>
    <name>A0A1D3RNV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TldE/PmbA protein, part of proposed TldE/TldD proteolytic complex (PMID 12029038)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_01495_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000666">
        <property type="protein sequence ID" value="SCN47324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="36"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="121"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="235"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="443" mass="47965" checksum="4565AFED9ABA1250" modified="2016-11-30" version="1">MQTQEEIKRLEAIIADLLLEAKTQGASQADAGLNVDNGLSVNVRLGEVETIEHHCSQGLGVTVYFGQQKGSASSTDLSPQSIKETVSAACSIARYSSADSFAGLPDPERLATDFKDLDLHHPWELNAEDAITLATRCEDSARHYHSDISNSEGASVDTYSGIRVFGNSLGFLHGYASTRHSISCSVLGERDGNMERDYWYSVARNKDQLEKVEDIGKKAAERTIQRLGAQSLSTRKCPVLYSAEIANSLIGSFLSAISGGSLYRKSSFLLDSLNTKVFPEFIHLYEQPHLLGALGSALYDAEGVATQANDIVADGIVKSYLLNSYAARKLGMQSTGHAGGIHNLCITPGDKDFTQLLKHMDTGLLVTELMGQGVNPVTGDYSRGASGFWVEQGVIQYPVQEITIAGNLKEMFQQILAVGNDIDYRSNIRTGSILIEEMAIAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV4</accession>
    <name>A0A1D3RNV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Single-stranded DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_48620_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000687">
        <property type="protein sequence ID" value="SCN47353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="67" mass="7695" checksum="65733DCB12C5BA38" modified="2016-11-30" version="1">MLNKVTLIGNLGADPEVRYMPTAGAVTNIRLATTERWKDKQTGERKESVEWHRVVFLIAWQKLQVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV6</accession>
    <name>A0A1D3RNV6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF262 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_66863_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000668">
        <property type="protein sequence ID" value="SCN47326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="23"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="353" mass="41370" checksum="914A401C6B21FEF4" modified="2016-11-30" version="1">MQTMSSKQSPRRVITQPYDYSVQDIVDKIKKGDIDLNPDYQRNYVWGANDDKEHKCSRLIESLLLNIPIPVIYFAEQAETLKYEVIDGQQRLFTFQRYLNDEFALNGLEIRDNVNDCKYSDLTSHDRDVIRKRSIRAIVILNDSDEQVKYEVFERLNLGSIQLTPQEIRNNTLRGSLNDLLKELARRPLLKKMLNLRLKSDKKNMALEELVLRFFAYHDSGYKRAHNLSFFLTDYLKKNRDLADAELDKLRVLFDSTLELVDKYLGEHAFSSYGVKTETWTAQSNRSLYDAEMLAFSQYVNKEIKIKPEQFIKQLEKLMGDSKFRKSLHSQSGGKMIERRVKNIDKIISSNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV8</accession>
    <name>A0A1D3RNV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-demethylubiquinone-9 3-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.64</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00412_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.64" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008689">
        <property type="term" value="F:3-demethylubiquinone-9 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="235" mass="25911" checksum="D0A364805A1A96BE" modified="2016-11-30" version="1">MTASENVHLHEINKFGSQAERWWDKNGEFKTLHDVNPLRINFIQKFINPQNMRIVDVGCGGGILTEGLAKKGANMLGIDLSEDLIDIADLHGLESGVKTHYQKISAEALAEAEPASFDHVVCMEMLEHVPEPGSVVAACAKMVKPGGYVFFSTLNRKPKAYLLAIVAAEHILKMLPAGTHDYKTFIKPSELSQSARDAGLELQGMTGIQYNPLTKNFSLSDDIDINYIAAFKRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW6</accession>
    <name>A0A1D3RNW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_363592_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000705">
        <property type="protein sequence ID" value="SCN47380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="52" mass="6036" checksum="D4429E4C13D98C8F" modified="2016-11-30" version="1">MDGRGRALDNIFVERLWRTVKYENIGSVARIAESEELLVFRHNYPAKAINCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY2</accession>
    <name>A0A1D3RNY2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13 14">UvrABC system protein B</fullName>
            <shortName evidence="13">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrB</name>
        <name evidence="19" type="ORF">BAZMOX_05058_1</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10 13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13 14">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000710">
        <property type="protein sequence ID" value="SCN47391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="26"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="430"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="16">
        <location>
            <begin position="629"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="253"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="606"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="13">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="SCN47391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="667" mass="76435" checksum="A3BF180678942078" modified="2016-11-30" version="1">MDKLFNIHSQFKPAGDQPTAIKQLIEGLNDGEVHQTLLGVTGSGKTFTIANVINEVQRPAMIMAPNKTLAAQLYGEMKEFFPENSVEYFVSYYDYYQPEAYVPASDTFIDKDASRNEHIEQMRLSATKALLERKDTIVVATVSAIYGLGEPESYFKMVLHLVRGDMINQRDLLRRLASMQYTRNDIELRRATYRVRGEVIDIFPAESEEAALRIELFDDEIERLSLFDPLTGEILHRVARYTVYPKSHYVAPREKLLEAVEKLKVELKDRLEQLRSMNKLVEAQRLEQRTLFDIEMIYEVGYCSGIENYSRYLSGRDDGESPPTMFDYLPDNALIIIDESHVTIPQIGAMYKGDRSRKETLVEYGFRLPSALDNRPMRFDEFESRVGQRIYVSATPSRYEKENSGRFIEQVVRPTGLLDPEIEVRPATSQVDDLLSEINIRVDKKERVLVTTLTKRMSEDLTEYLMEHGVRVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSVVSLVQTIGRAARNSNGKAILYGDKITKSMAQAIEETQRRREKQMLFNAQQGITPTTIFKSVTDILEATIPGAGLNQASKNKVAEQKNNYTALSQKEKEKKLTQLENQMYKYAKNLEFEAAARVRDDIKQLQLEMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP02</accession>
    <name>A0A1D3RP02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_43592_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000735">
        <property type="protein sequence ID" value="SCN47420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032877">
        <property type="entry name" value="Transposase_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13542">
        <property type="entry name" value="HTH_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_ISL3" evidence="2">
        <location>
            <begin position="27"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="93"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="242" mass="27215" checksum="A93F4DB82FC61563" modified="2016-11-30" version="1">MNFFEHSCLLHCAVPRIKTTDGKVRTVEVPWARPGSGFTLLFEAMALAMIERDMPVNRVAEMLKVNPHRIWTVFNHWIGKAKAADDVSSITQLGIDETSSKKGHKYVTLGVDLEESRVIFVTEGKGKAPLHNIQKHLEDKGVEKEQVEPISMDLSPSFIAGASEAFPEAAITFDKFHVVKLLNEAMNQVRIDERKEHDALKGHKYTFLRNRDNLTNKQEASLAEMIDLYPTLGAGLPIKRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP10</accession>
    <name>A0A1D3RP10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_45768_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000732">
        <property type="protein sequence ID" value="SCN47413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="10793" checksum="A748FCE879876224" modified="2016-11-30" version="1">MDKSGANYAGLANISLLLILAGFATMIDICQVKYLNNIVEQDHRFIKKITKPMMEFKAFHSAQETITGIETAHMIQKGQLSEENIPAYKRFMALEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP57</accession>
    <name>A0A1D3RP57_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UPF0114 protein BAZMOX_37982_2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_37982_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the UPF0114 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000776">
        <property type="protein sequence ID" value="SCN47473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00143">
        <property type="entry name" value="UPF0114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005134">
        <property type="entry name" value="UPF0114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020761">
        <property type="entry name" value="UPF0114_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38596">
        <property type="entry name" value="PTHR38596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03350">
        <property type="entry name" value="UPF0114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00645">
        <property type="entry name" value="HI0507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="163" mass="18539" checksum="D1FA4A13E73901A1" modified="2016-11-30" version="1">MIERIIERSIYACRWLLAPIYLGMSIALMALTVKFFQELYHFIPAILDMSEGALMLKLLAFIDLTLVSSLTIIVMFSGYDNFVSRLDIAEGTEKLSWLGTHDYGSLKMKVASSIVAISSIHLLKVFMNAEQIANDKLLWYVVIHLTFVLSAFMMGILEKKEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP60</accession>
    <name>A0A1D3RP60_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ORF">BAZMOX_04294_1</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="FMJP01000755">
        <property type="protein sequence ID" value="SCN47436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="144"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="177"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="199"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN47436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="222" mass="24289" checksum="18497E07B8BE6BC4" modified="2016-11-30" version="1">MADNWIAPSILSADFARLGEEVDNVLASGADIVHFDVMDNHFVPNLTIGPLVCDALRKHGVTAPIDVHLMIEPVDRIIPDFAKAGASMITFHPEASTHIDRSLQMVRDLGCKSGLVFNPSTPLHFLDYVMDKVDIILLMSVNPGFGGQSFIPGTLDKLREARKRIDDSGYDIRLEIDGGVKVDNIREIKAAGADMFVAGSAIFSQPDYKKVIDEMRAELAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP64</accession>
    <name>A0A1D3RP64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_09742_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000759">
        <property type="protein sequence ID" value="SCN47444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="98" mass="10882" checksum="2B8DBBEDB3F9F678" modified="2016-11-30" version="1">MLDEVIKVVTPEVIGYVAATLTTVSFLPQAIMTLKTRDTESLSLGMYSSFTLGVLLWLIYGVCIADKAIIYANAVTFLLASLILSFKIYNILWKKKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP68</accession>
    <name>A0A1D3RP68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsU</name>
        <name evidence="6" type="ORF">BAZMOX_10702_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000679">
        <property type="protein sequence ID" value="SCN47339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018278">
        <property type="entry name" value="Ribosomal_S21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01181">
        <property type="entry name" value="RIBOSOMAL_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="77" mass="9206" checksum="991F7BA4870D75A4" modified="2016-11-30" version="1">MPAIKIKENEPFDIALRRFKRSCEKAGILSEVRRREFYEKPTAERKRKAAAAVKRHLKKLSRERYALKNLRRGRPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP88</accession>
    <name>A0A1D3RP88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <ecNumber evidence="6">1.17.7.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_04655_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000620">
        <property type="protein sequence ID" value="SCN47257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="100" mass="11211" checksum="C1BC8A29F0D36840" modified="2016-11-30" version="1">MKIELANPRGFCAGVDRAIEIVDRAIEAFGAPIYVRHEVVHNRTVVEGLRDKGAIFIEELSDVPEGSYLIFSAHGVSKKSTKRSYRKEINCIRCNLSFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP91</accession>
    <name>A0A1D3RP91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_41472_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000778">
        <property type="protein sequence ID" value="SCN47474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="69" mass="7485" checksum="2D801484451E8FE7" modified="2016-11-30" version="1">MPAISLVNDVQMITAIASTQHYDDIFAKQLRALGQASDVLLLYSAEESSLNLVRLINAAHDKKTDGNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP98</accession>
    <name>A0A1D3RP98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_15154_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000694">
        <property type="protein sequence ID" value="SCN47369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="217" mass="25711" checksum="F07F9F4224178CFB" modified="2016-11-30" version="1">MYERLSKIDSLTRSDHHYLEDSDLCYYFGEYTARKGFEKSYTNQLILNFKKSVDRKDRTEYKYKLRAIKVIADLLNNHFVHTEKVTFVPVPPSKNRDDPLYDERMASVLEQFKVLNNNVDYRDFIIQSETTEASHNASNRLSPQEILKLYSLNESLVNNIRKNIFIFDDMLTTGSHFKAIQLLLLERFPEKKIFGIFIARRAIEAIDWDFDADIFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA7</accession>
    <name>A0A1D3RPA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_34354_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000813">
        <property type="protein sequence ID" value="SCN47540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1660.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032388">
        <property type="entry name" value="FlgT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038165">
        <property type="entry name" value="FlgT_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032386">
        <property type="entry name" value="FlgT_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032370">
        <property type="entry name" value="FlgT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038180">
        <property type="entry name" value="FlgT_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16538">
        <property type="entry name" value="FlgT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16539">
        <property type="entry name" value="FlgT_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16548">
        <property type="entry name" value="FlgT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920280" evidence="1">
        <location>
            <begin position="18"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="FlgT_N" evidence="4">
        <location>
            <begin position="31"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="FlgT_M" evidence="3">
        <location>
            <begin position="121"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="FlgT_C" evidence="2">
        <location>
            <begin position="328"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="408" mass="45640" checksum="A945FCE7BDC8526B" modified="2016-11-30" version="1">MQSANYLLLIFCLLLQACSTTKIPSQSIEQIVTIEGQATIRDGAQLLARKMAIRDAIRQASLQNNSQINSLTLINQNSIALDSFTLRTTALINNTKVIDEWIENDIYHVRAIVRLTTGSMCTPQYRKRLAATAFPMVQRSHTSMAESNDLSNGIPREISNMLTQSGAYLGRNKTHTSLYAQPDLAPEITGTRPYDISDDMTLAQRSRVQLVLSGVIRDLESSSRQYYRGTGISAWIKSLNHYFFTTRSITIDIYIHDGYSGALLFQHRYKDQASGDIRIPKDVMVGSEAFNNTDTGNKITKIINQSVKDIQESLNCYPFYTRILKIEDNKIFIDAGAQERLNEGDQLVVYSSLGTINQFGGTQQILGFDKKPTGVLTIKKITPLFAIGELEAPPHMLGIKVGDWVKSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB2</accession>
    <name>A0A1D3RPB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_326077_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000771">
        <property type="protein sequence ID" value="SCN47462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4409" checksum="EAB89EAB56F06550" modified="2016-11-30" version="1">MANFPVAYCGLKIITSLSLRFPDFQREPKTEIMSANATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD2</accession>
    <name>A0A1D3RPD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, Gfo/Idh/MocA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_29893_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000643">
        <property type="protein sequence ID" value="SCN47297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="297" mass="32681" checksum="6AD6516DF77F0D7F" modified="2016-11-30" version="1">MGKFHAEKYASLPDCELVAVVDINEQAAKDVAEKHGAEALTDYQSLLGKVDAVSIVVPTTLHHQVSKDFLNAGTHVLVEKPITVTVEEADELIVIAKEKNLILQVGHLERFNPAVMGLGELEDKPLFIESHRLSPFNPRANDVSVVLDLMIHDIDIILAIVDSEVERMEASGTAVLTKGTDIANARLTFKNGCVANVTASRISMKMERKMRMFRPNSYISIDFQNRVLTKHFAGAKEMFPGVPEIETEKSVFENGDALLEEIKHFVDCIHTGNTPDVSGDAGRRALATAIEITKLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD8</accession>
    <name>A0A1D3RPD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfonate ABC transporter, permease protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_05330_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000832">
        <property type="protein sequence ID" value="SCN47570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="57"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="250" mass="28349" checksum="D78CA0D3F2329084" modified="2016-11-30" version="1">MDFIYHRSILNLLSMSAFLTLWYGLALFLNADTLPSPVTVAKVLITEIQSGQLSYHLSKTLYRLSISFSIAMLLGCAIGIVLGRHQKLNTFLDNWLVIFLNIPALVTIILCYVWFGLTETAAILAVVINKLPNVIVTIREGARSLDTELLDMAKCYRFSKSKTLRHVIWPQLHPFVMAATRSGLALIWKIVLVVEMLGRSDGMGYQLHLFFQLFDVASILAYTVAFITLIQGIELLILRPLDKHAQRWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE7</accession>
    <name>A0A1D3RPE7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ion-translocating oxidoreductase complex subunit G</fullName>
            <ecNumber evidence="6">7.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Rnf electron transport complex subunit G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnfG</name>
        <name evidence="9" type="ORF">BAZMOX_36003_2</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RnfG family.</text>
    </comment>
    <dbReference type="EC" id="7.-.-.-" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000660">
        <property type="protein sequence ID" value="SCN47317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00479">
        <property type="entry name" value="RsxG_RnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010209">
        <property type="entry name" value="Ion_transpt_RnfG/RsxG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36118">
        <property type="entry name" value="PTHR36118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006091">
        <property type="entry name" value="E_trnsport_RnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01947">
        <property type="entry name" value="rnfG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0288">FMN</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="8">
        <location>
            <begin position="108"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="6">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="231" mass="25055" checksum="7AB52F31D9B88004" modified="2016-11-30" version="1">MSTPENQVPEMPSSTKLISTLAVVAMISGLLVVLVYEFTKPIIAENQRLATERAIFKVLPKAISRLTFVVENDKLTPADDKTVGELVYAGYDKNDQLVGIALNAAAQGYQDTVKLLYGYQANSGCITGFDVLKSTETPGFGTKITTDPDFLANFKCLDAKVNPEQSGLIHAIKTVRHGTKQHAWEIDAISGSTITSNAIGRMLNKSGQALHPIITKNFSLLETAKIQSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF0</accession>
    <name>A0A1D3RPF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_05330_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000832">
        <property type="protein sequence ID" value="SCN47571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="244" mass="27638" checksum="5576A096C26B1823" modified="2016-11-30" version="1">MNNLTINILDKSYTTPTDKNSKQVIKNFQLNLANNEFICLVGPSGCGKTTLLNILAGLDETFSGNIALSESHTLPKVGYVFQNPRLLPWRTVQENIELASEAKIDTLDFLLESMGLAAERNTFPAHLSLGMSRRVAIIRAFAMDPDLLLMDEPFVSLDPPTARQAQQLLIDLWSKRPHKVLFVTHDLREAITLADRLIFLHSNPMSVIREIPVSIPRSERQNEVKIEQFRQQLFIDYPEITTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF9</accession>
    <name>A0A1D3RPF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_47653_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000709">
        <property type="protein sequence ID" value="SCN47388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="169" mass="18303" checksum="7D2D904E68EBF3F7" modified="2016-11-30" version="1">MGCSSFSSKQKPAPVYGQIDSSGRLAGRNDNAVISTPVTTKPITVQESTILNQQDVEIKPQAKSANVVIALLADADNSYQQGNVDESVATIERALRIEPRNALLLYKLAVLKLAQEEPEQAINLAKKSALLAEGNSGLKKKNWLLIADIYEQQGDLANANVARQKAQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ0</accession>
    <name>A0A1D3RPJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_76214_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000868">
        <property type="protein sequence ID" value="SCN47611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5596" checksum="2242ED95D55838A7" modified="2016-11-30" version="1">MCYLLIFVLNSKTFVSKKQNNYILTDKKNLPCLSKNGVEITRNADFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK6</accession>
    <name>A0A1D3RPK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase beta' subunit</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_24983_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000836">
        <property type="protein sequence ID" value="SCN47576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb1_5" evidence="1">
        <location>
            <begin position="110"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="353" mass="38373" checksum="5416D13C7E2C122B" modified="2016-11-30" version="1">MTGVSSVTVLDPKQRVSAGKDLRPLVRLVTDDGEEIMLPNTDLTAQYVLPSGSIVAVKNGAEIQVGDVLGRIPQASSKTRDITGGLPRVADLFEARKTKDPAILAEATGAVSFGKETKGKQRVIITDSEGEQYETLVPKWRHITVFEGEFVDKGETIAEGELTPHDILRLRGVTELTTYLVKEIQDVYRLQGVKINDKHIEAIIRQMLRKVEITAAGDSNYTKGDQVEKAAVKVINDQLEADGKVPASYDPILLGITKASLATESFISAASFQETTRVLTDAAVRGLKDPLYGLKENVIVGRLIPAGTGLAFHEARRKRQLKQEVSMNASEEVKTSDAVVDAEEALKQALNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL6</accession>
    <name>A0A1D3RPL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01548_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000761">
        <property type="protein sequence ID" value="SCN47448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="306" mass="35146" checksum="027E5F9B8E4F02E5" modified="2016-11-30" version="1">MTIILTPTQQRAVYYSPLSFLRGHEQSLATSFLEDLDKAINNGVVERIGQDVKIWVRYLEWDSQYFSCPTYRFEFSNWDSDAIGPATSVAEKLIELKAELLRRHGNYYLFTEIPSEDVVVLQALGLSGFRLIETRLTHYIDELESFEEQSSLPVRVARKDDAENLRDVAICSRNDFDRFHADPFFSDLVADDYLAEYTEQCILGLTDTVLVPDVDQLLPNAFICGTLNIDAPNEMHIGRLVLVAVAEPRRGWYRHLNSALLIWMKNNGMSYCVNRTQSTNRAVIHVCEQLGYRYGRSTHLLATYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN8</accession>
    <name>A0A1D3RPN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclic nucleotide-binding:Bacterial regulatory protein, Crp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_16663_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000845">
        <property type="protein sequence ID" value="SCN47592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="27"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="150"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="283"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="332" mass="37724" checksum="270E5BA273509039" modified="2016-11-30" version="1">MIDNNEGSEKEAKSKGDWMSTLLKSPIFQRLPAMNLQQVIMSLQEIKLNKGEVLFRQGDIGDYYYLVREGRCTLSRKATERAKEIILTELGENETFGEDALLSGEPRSMTITAATDMVLSRIDKERFIKLIKTPALKYITYPKLLEEQAKDTAPLILDIRPVNKYNETHIEGSRNLPFFSLRMQLKDLKKETKKIIIICADGTLSEAAAFTLIRNKIDAVILKGGMQNVPKNTSYAGEATFTIDDNDQKSHIFFERGETASEDISSTIDQQTNSPDSLNQETELDLQKENTHLKAENTRLSNELDSAKKQYRMLYKQTEKLKGILDKLKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW3</accession>
    <name>A0A1D3RPW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_45097_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000948">
        <property type="protein sequence ID" value="SCN47731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="34"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="119" mass="13616" checksum="DB7BBEBB2C923FAE" modified="2016-11-30" version="1">MKEGEKMDKDMDMSGGNMKMGGGMGMMGGGMMMSMAHPIHLHGQQFQVLSREIEGMRQEEYKTVKEGFLDTGWKDTVLVMPGEEIVIAKPFQDYKGLFLYHCHNLEHEDLGMMRQFYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY6</accession>
    <name>A0A1D3RPY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formiminotetrahydrofolate cyclodeaminase</fullName>
            <ecNumber evidence="2">4.3.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00950_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="4.3.1.4" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000793">
        <property type="protein sequence ID" value="SCN47497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030412">
        <property type="term" value="F:formimidoyltetrahydrofolate cyclodeaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007044">
        <property type="entry name" value="Cyclodeamin/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036178">
        <property type="entry name" value="Formintransfe-cycloase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04961">
        <property type="entry name" value="FTCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101262">
        <property type="entry name" value="SSF101262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FTCD_C" evidence="1">
        <location>
            <begin position="9"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="209" mass="22141" checksum="F4DFDB29FDDF2A8C" modified="2016-11-30" version="1">MSEIKDKSIELFLNELASRSATPGGGSVAALMGAQSAALTSMVCNLTIGKPKYIEVDTQMQALLAKSEALRTSLTEMIKADVDVFDRLMLAYGLPKETDEEKAARSKQIQVVLKAATLVPLACAKACAEAIELSQEAAEKGSVHVISDAGAGAMSAYAGLKSAALNVYINTASLKDRAFADAQLIELESILSDAELKVDNIYQVVKNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ1</accession>
    <name>A0A1D3RPZ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_47804_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000986">
        <property type="protein sequence ID" value="SCN47773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="113" mass="13210" checksum="25EE85FF1A28550D" modified="2016-11-30" version="1">MYRSNAQSRLFEEKLMAMGMPYRVYGGLRFFDRMEIKNALAYSHLSAHKGNDAAFERIINTPTRGIGTKTIDNIRHLAREQQMTLWQAMISLLKARTFYTTRRKCTERLCADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ11</accession>
    <name>A0A1D3RQ11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_532623_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000959">
        <property type="protein sequence ID" value="SCN47744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4603" checksum="A92F0CD46B8B2302" modified="2016-11-30" version="1">MKLTHNLSYPLLLVIFKSAIFLHNVWSGWAGAVPLSTGGESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ39</accession>
    <name>A0A1D3RQ39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_86659_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001044">
        <property type="protein sequence ID" value="SCN47865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="52" mass="5584" checksum="B426E40B2AB0808F" modified="2016-11-30" version="1">MDKSGANYAGLANINLLRSPWLAAVANPLKNTPCLPIYAPKTGKLQFLNISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ92</accession>
    <name>A0A1D3RQ92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="1">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="1">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_30428_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01001017">
        <property type="protein sequence ID" value="SCN47824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="HXTX 1" evidence="1">
        <location>
            <begin position="39"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="1">
        <location>
            <begin position="121"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="169" mass="19535" checksum="2AEB99BC4CD51E54" modified="2016-11-30" version="1">MKRLFFALWPSVATRKAVDKFNQTLKVPGLKTVKADNLHVTLVFLGNVDRQTERLIKRKVSGISAQQFMLNFNQLAFWHKPRILCLLSQTIEPQLLSLVDALTQVAEQCAIKVEDRPYQPHITLARKAQELINTNVLGIEWYAHSFCLVESCRTTEGVQYRVVRQWKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ93</accession>
    <name>A0A1D3RQ93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I restriction-modification system, restriction subunit R</fullName>
            <ecNumber evidence="1">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02029_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.21.3" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01001039">
        <property type="protein sequence ID" value="SCN47861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="324" mass="37999" checksum="4F5A77307974B178" modified="2016-11-30" version="1">MNANCIPSLDKEIRGISAIQTISRVNRTTKYKNDCKIIDFSYDNVNVQNIKDAFEHFSDVVVSDFDPFSDKRVLDLLLTELKKSEIYQKFFNPFMQIYKDADRRDDPESYLDIESSIEKFIDANPKRTADTKAKTAQYFTILNRIEYVVDLESKFSDPSFLFFLRKFNIIYNMMHRSDDVKDPIEVYFDNQIGIIEVETGEPEKKKKKKIKVAVGAEEGEPHQFDILKIIEARNEKEAIVGTLIKEFEEKIQDLFDFVRAQEDGKRLIVKIKSQVSEDEIYDDFAKLYRRYKALNRKKVGDYFFKEMEDLVDKLCADFEATVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA4</accession>
    <name>A0A1D3RQA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_31641_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001048">
        <property type="protein sequence ID" value="SCN47871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4530" checksum="C9CC7CF9D9640C06" modified="2016-11-30" version="1">MHRKKSSFLYCWRGKPLIHKIGIISAVIIASACYVMFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC1</accession>
    <name>A0A1D3RQC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell division protein FtsH</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_29650_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000885">
        <property type="protein sequence ID" value="SCN47637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="188" mass="21257" checksum="52F2255398422AD7" modified="2016-11-30" version="1">MSATVLATELKLPLYTVVLDNLITRFMGETAAKLRLIFDHIKQTRAVYLFDEFDAIGTQRGAQNDVGEIRRILNSFLLFVEQDSSESIILAATNHPELLDKALYRRFDDIIQFEKPGKKQIKILAENRLAMFDTDSLIWNEITSLAVGLSSADVTRACEDAAKEAVLHHKAHLSTELIVKAIKRRKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC9</accession>
    <name>A0A1D3RQC9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">recF</name>
        <name evidence="6" type="ORF">BAZMOX_07461_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RecF family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000893">
        <property type="protein sequence ID" value="SCN47647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="SMC_N" evidence="5">
        <location>
            <begin position="3"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="362" mass="41203" checksum="5481B8D1674F633B" modified="2016-11-30" version="1">MSLQKLDIYHVRNLVQVSLAPAAKINLIYGNNASGKSSILEAIHLLGRANSFRSTTVKNVIHFAHNDLIISGKVLFTSGHVSTLGIQHDGKNMQIRIDQETKHARADLAYALPLQLIHPKSYQLLDAGPQLRREFIDWGIFNQHTEFLSAWRNFKTALSQRNALLKVRRVNELNVWDHELQQYGTIVADYRQQYLAELSPFFLKTVEQFLDIESVELLLSQGWDAESLLIDKLKNDLEKDLRYGFTHSGPHRADFQLLINSRKAKDFVSRGQLKLLVLALKLAQIEHLLNNGFQSGCILIDDAVAELDFSSRTKLLEFLAGMDIQVFMTATERNEFGDLSQIGQYKMFHVKHGEVTEVSCFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQH6</accession>
    <name>A0A1D3RQH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I restriction-modification system, DNA-methyltransferase subunit M</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_49013_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001085">
        <property type="protein sequence ID" value="SCN47914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="155"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="378" mass="42768" checksum="0A1692060D0BA27E" modified="2016-11-30" version="1">MLRGSGIKESEWPSFMMPFFALAMIESRLIRMLDELKEEIGEDAIAYIDKEDFIDLIRDRGQGYNVYIFEHGKTLKDICANDKSFDIDFDAYLHGFDGETKDLLGVDASEGEKFLDIKGVVTKLKAKKVLLGYTKEWSEIDLKPFNNSEITTLEEHIKRKWADISAETAGEQYTPDDVIGLISEIIASKVQESDTLLKIYDCSCGGGNMLFGVEDRINQKLNRLTQTFGQDWNDALYALAKIESRFRTDSKIEHGNTLTDDKFYNEEFDVVVANPPYGVSWKGYQKDIQNDKTERFKYLPSVSDGQLLFMQHLVSKLDSVGMGVVVHNGSTLFSGNAGSSGSNIRKWMLDTDIVEAIIQLPTDEFLQYGHLYLSLGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQL5</accession>
    <name>A0A1D3RQL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00666_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000962">
        <property type="protein sequence ID" value="SCN47747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="186" mass="20817" checksum="68DD4AF2D6237322" modified="2016-11-30" version="1">MLLIVGCAGNGGKVQEGEVTAYDLYNKNRPDTSLADTGISSGNVITSAIAGIYEKTVNLENQYKKRIENNKVALILDRIRLEQGEAAYKKEYSELGVKDKAIYDVFLKNNINTLEVAVGYAVEAKKMASGVKNFDYKKYIVNPMAKYKTITALSKATEQIQYTEKALEFMVETRTISEAMLDFEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQS9</accession>
    <name>A0A1D3RQS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Cysteine synthase</fullName>
            <ecNumber evidence="5 11">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BAZMOX_12951_2</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="5 11"/>
    <dbReference type="EMBL" id="FMJP01001066">
        <property type="protein sequence ID" value="SCN47888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005858">
        <property type="entry name" value="CysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314:SF100">
        <property type="entry name" value="PTHR10314:SF100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01138">
        <property type="entry name" value="cysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="8"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="176"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="296" mass="32066" checksum="B5228060F2B07DE4" modified="2016-11-30" version="1">MTYSTIEAFIGNTPLVKLQRLIKQSSNTVLVKLEGNNPTGSVKDRPAISMIKHAEARGEIKPGDRLIEATSGNTGIALAMAAAIKGYKMTLIMPDNMSSERRASMKAYGAEIILTLAVGSMEAAIDFAREMEAEGKGRILDQFSNPDNPRAHYEGTGPEIWRDTQGQITHFVSAMGTTGTIMGTSKFLKEQNPEVQIVGVQPEDGAKIPGIRRWPVEYLPKIYQATRVDKIMNMDQQTAEQTMRDLATQEGIFGGVSSGGAVAAALRLAQEVENATIVAIICDRGDRYLSTGVFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL82</accession>
    <name>A0A1D3RL82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III chi subunit</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01179_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000036">
        <property type="protein sequence ID" value="SCN46430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007459">
        <property type="entry name" value="DNA_pol3_chi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036768">
        <property type="entry name" value="PolIII_chi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38767">
        <property type="entry name" value="PTHR38767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04364">
        <property type="entry name" value="DNA_pol3_chi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102400">
        <property type="entry name" value="SSF102400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="143" mass="16725" checksum="DE19493B32B5133F" modified="2016-11-30" version="1">MLPKVNFYVLLSRSEQGRQLFACKLAEKAFRLGFKAYILTDTRQQAQQLDTLLWTFRANSFVPHEIYQSDLPSRANAVIIGTQQAPEAWRHTLINLSTYCPEQVHQSEQIFELLDNDETHKQAGRKRYRLYQQQGITPNTHKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL95</accession>
    <name>A0A1D3RL95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">COG1821 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01476_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000038">
        <property type="protein sequence ID" value="SCN46440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003806">
        <property type="entry name" value="ATP-grasp_PylC-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024710">
        <property type="entry name" value="MfnD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040803">
        <property type="entry name" value="MfnD_preATP-grasp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02655">
        <property type="entry name" value="ATP-grasp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18301">
        <property type="entry name" value="preATP-grasp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016766">
        <property type="entry name" value="UCP016766_ATPgrasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="133"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="333" mass="37579" checksum="51F1F178A6ACE35B" modified="2016-11-30" version="1">MRLLVFEFITGGGFINQPLPPSLLQEGYLMRNALLDDLCLLNKLELLILHDERIAFATETGHEHLHYLIISADKDIQAVLLDQSDLYDAVWLIAPETEGILARWAQFFNEQGKKMCLSGQEAIDLCQDKLATFNRLQKAGVACIPSFLFTSKVVIEPGLWVLKANDSAGCDEVYLLQEEQHWKAVLAKLIPEHRYILQPYIAGKVLSLSCLFYQGRAFFICCNEQQMTIERQQFILSACRVNVQTEKCQQYQQLCQSIAAAIPQLFGYIGIDFIETEAGENLILEINPRLTSSYAGINEATGLNVAELVLAMLNKKIPIFKKTKNHPVLIDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLG4</accession>
    <name>A0A1D3RLG4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">pEK499_p136 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_258785_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000069">
        <property type="protein sequence ID" value="SCN46484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041318">
        <property type="entry name" value="pEK499_p136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18736">
        <property type="entry name" value="pEK499_p136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="pEK499_p136" evidence="1">
        <location>
            <begin position="25"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="179" mass="21122" checksum="20AF891460B69C4C" modified="2016-11-30" version="1">MSNLTDQISICCAVNSAIMSDARSKKEFIESSKNVVKKLKIVPPKDTNNNVWPFFNSSWDAYHLYCLIVVPKELYGLRNDDPFYQKLKAKKIFRNFNIIKSEKSPIDNLEYHFRSLRNSISHVNFSIGNDSSYTMWDHLPHKKELEHWRVKISKPNMIIFFEEMADSLFDIYNERHPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLH3</accession>
    <name>A0A1D3RLH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_63318_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000023">
        <property type="protein sequence ID" value="SCN46419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="3"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="67" mass="8220" checksum="30156B158D520242" modified="2016-11-30" version="1">MDGRGRALDNIFVERLWRTVKYENIYMNEYQTVPELRSGLKRYFEFYNQERLHQSLGYKTPSEVHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL6</accession>
    <name>A0A1D3RLL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="4" type="ORF">BAZMOX_09208_3</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="FMJP01000141">
        <property type="protein sequence ID" value="SCN46571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="188" mass="20748" checksum="067CD24D27CEB774" modified="2016-11-30" version="1">MIKLVVGLGNPGQKYAKTRHNAGFLLLDELISAGSAFFSPQSRFFGELAEMRVGGGRFYLLKPATFMNRSGQSVSAVMKYYKIQPEEVLVLHDELDFELGVLKLKFGGGHGGHNGLRDIIAATGSKDFLRLRVGIGRPQGSQAVADYVLSDFTRRDFELLMSRFSDFHTLIPLLLAGDTESAMHKLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP8</accession>
    <name>A0A1D3RLP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromosome (Plasmid) partitioning protein ParB / Stage 0 sporulation protein J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_00589_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000166">
        <property type="protein sequence ID" value="SCN46601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013741">
        <property type="entry name" value="KorB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08535">
        <property type="entry name" value="KorB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="3">
        <location>
            <begin position="26"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="339" mass="38366" checksum="D8B0056955E69B43" modified="2016-11-30" version="1">MKNINLSSIDNLALSLDQPQKGEKITLLSLDKVIPDPDQPRRDRNKEADNELANSIKEEGVIQPIIVRPENDDGYHMIICGERRYDGSKKAGLDTIPCIVRDIESSMILTIQTVENIQRDNMSLADEIEAVAKIAKVHGTKKTAELLGKKSQYVSKRVRIYKANSYLWDFIKLGYSNDFAAFYELALLDSKNHDEAKILVDSWILSPTIRTSLRTQVEDIKRRLSKPKKNNVIDIDSSNDVDAVKLNDDVIESINTIETVLNDSSDSTMENGKKEKNKPKKVKKDKPLNVGGVPDSFKVESLQDRKLLSFTFDDGVLIDIEISNDDWMNFVNEVNKEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS3</accession>
    <name>A0A1D3RLS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M23B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_63318_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000023">
        <property type="protein sequence ID" value="SCN46417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="1">
        <location>
            <begin position="166"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="301" mass="33775" checksum="9019157BE4EA8E7E" modified="2016-11-30" version="1">MQGEAKKLYKYQDEEGGWHYTDKAPSARQSEEFKVEVRQLKAASKERVRLRQVGEKSQPEFVIENDYFGPIEVEVTFYKQENVQASPALPRKFVILPGISKPLFKLGAINEFKSWRYGLSYSYSLGKPLAQHDVAARYYPPFASYRKFQVSQAFNGTFSHTDQQNKYAVDLAMPEDSEVHAARGGVVMSLENDYVKGGVDKQAYKARSNSIRILHDDGSMAVYAHLQVGRAQVYVGMRVQAGQLIAYSGNTGFSSGPHLHFAVQVNQGMNLVSVPFGFTDTRGKVSPPKAGRWLKGFAIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS9</accession>
    <name>A0A1D3RLS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smpB</name>
        <name evidence="5" type="ORF">BAZMOX_00299_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="160" mass="18586" checksum="0E3A1F94D28D7208" modified="2016-11-30" version="1">MAGKSSKKKKQTDNIIAKNRYVAHEFFIEERFEAGLVLEGWEVKSLRAGRVQLKESYVFIKNGEVWISGMHISALNSASTHVTPYATRVRKLLLKRQEINKLIGNVERKGFTLVPTFMYWKNSRAKLEIGLAKGKKLHDKRATEKDRDWQREKARNLKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT4</accession>
    <name>A0A1D3RLT4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="9" type="ORF">BAZMOX_08668_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000180">
        <property type="protein sequence ID" value="SCN46626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="542" mass="60620" checksum="4C1F9A6EAA268C8E" modified="2016-11-30" version="1">MSHLTNSSEWQALKAHQQDVNPLHIRDLFAADPSRFNSYSILFDDLLFDYSKNRITEDTLPLLFKLANACQLKTHITDMFSGKRINKTENRAVLHTALRNRSNTPVYVDDVDVMPQINHALQKMRDFCSAVHSGEWTGYTGKRITDIVNIGIGGSDLGPKMVTKALTPYAIEGMSVHFVSNIDQADLVETLSQVPPETTLFLVASKTFSTHETMTNASSARSWLLNHANNDKSAVAKHFIALSTHKTNVAEFGIDTHNMFEFWDWVGGRYSLWSSIGLSIALYLGMDNFEELLTGAHEADKHFQTTPFEKNIPVIMGLLGIWYNNFFGAESHAMLPYAHTMQFFADYFQQGDMESNGKSVDLEGHPTDYSTGPIIWGQPGTNGQHAFYQLIHQGTKLIPCDFLAPAQSHYDLAEHHDILISNFLAQTEALIKGKTAEEVKAALGSDASENLIAAKVFSGNRPTNSFLFEKLTPHTLGKLIALYEHKIFVQGKIWNINSYDQMGVELGKILAVKILPQLESDTPVTSHDSSTNGLINYYKKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU5</accession>
    <name>A0A1D3RLU5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PpiC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_07213_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000124">
        <property type="protein sequence ID" value="SCN46549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="255"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="617" mass="68455" checksum="8C7626E8F3752C9C" modified="2016-11-30" version="1">MLSKIREKTQGTFAWVILILICVPFALWGLQNYTEGGQESAVVIVGDKEFVQRDVNQAYAQFKQQYADMQLPEEILKKQAIEKLIRDELLLQHVTAEKLSITDETVRKFIASLQYFQRDGRFDKKQYETLLATQGMTSAQFVNRIRKALLMEQYQKAITESSFVSQHDIDSFFKIQNQTRHIEYVTVNVQPVSDLPTSDEINAYYQQHINEYQSAEQVSVEYVELLIDDLMADIAPTEEQLKAYYEENKELYSTKERRKISHILFAKTKDTTEEQALAKAEAAQARLASEKFADLAATLSDDSLTAKNGGDLGLFEVGVMEPDFEKAAAKLALGEVSKPVKSAFGYHLITVTELVPAQTKTFSEVKNEVQQAVQRVEAETQFYQLAESLTDISFENSDNLQIVSDDLGLTIKRSGLFGRSAGEDIASEESIRNIAFSESVLQGHNSEPIELGDSRLVVLRLLEHLPSEAKPLASVQQEIIAAIQSNKAKAQARTVAKSIKAQLESGVSLSDAAKEQGLVVTEMTELKRNNGDLPWQVSQAVFKAAKPIAGKPTVLVVDSIEGDQTVVSLLSVSDGTKDDEAEQVKLAAANIARALGQADYSAVIEGIRAVTKVIVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV1</accession>
    <name>A0A1D3RLV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_19324_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000188">
        <property type="protein sequence ID" value="SCN46642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="203" mass="23098" checksum="1E8D1DB0785EDF13" modified="2016-11-30" version="1">MTLKNISLILVIQFLTLSIAHSNEKNPLFDGTMLKIPIVDTQEHFGLYQNVEFKPLADGKWELAGYNKREKGIYEIETVNLFLTEEPPIQGFLEVTAFPRDCRMDTRLIRTQLVGDTFKVFIDSNKRPGTSACQKMRPLPFAEIIPLPLYGIKSGDYKYTVNGEYQGVFNVSSDNVLEIQPLEDREWDGTVADRNDVHGVGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV8</accession>
    <name>A0A1D3RLV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase, Gfo/Idh/MocA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_15446_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000184">
        <property type="protein sequence ID" value="SCN46634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="143"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="338" mass="37595" checksum="6F6FC7F9A3873B07" modified="2016-11-30" version="1">MPTSNKLHWGILGAARINQQLMPAIVNAKNSKLNAISSRRAGAAEALLKEYASQVEQVQVYNDPTDLLKDPNIDIVYIPLASQDHAQWTLRAIEQGKHVLCEKPMALSVADIEAIEVAAKKHNVYVMEGFMYRFHPQHQRIQEIINAGTIGTVRLVRTCFAYPMQPARLYRIDRDISQGGGAMWDIGCYAIHAARLYFDNTQAQAVTLLAKYNANGADVSSSGMIDFGDGKYAQFSFSFEHARRAEYEIIGTKGGLKCHNVWAKQTEEPIISWSTDSGKQQTETLNAANHFQLEVEHFSDCILKNTPPKLSLQDAKDNCTIITAALQSAEQGKTIQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX7</accession>
    <name>A0A1D3RLX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-ribofuranosylaminobenzene 5'-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_06146_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000227">
        <property type="protein sequence ID" value="SCN46705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004422">
        <property type="entry name" value="RFAP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF6">
        <property type="entry name" value="PTHR20861:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004884">
        <property type="entry name" value="Sugar_kin_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00144">
        <property type="entry name" value="beta_RFAP_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="1">
        <location>
            <begin position="72"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="309" mass="32708" checksum="01150760CDB65890" modified="2016-11-30" version="1">MAPARLHMGFIDLSGSLGRHFGSIGVALNEINTTLSLGYADTLTVSSHAPKRTLSCIKELCANLNVADKLQLDLHSNIPEHIGLGSGTQMAIAIGMALNAFYDLGLSVRDIAALTDRGARSGIGIAIFEQGGLIVDGGRGEQTITPPVIARMNIPDDWRFILVFDKRGKGLHGADEIQAFKELPPFPPQEAARLCYLLMMQGLPALAENNINLFGDVITQVQSSVGEHFSGAQGGVFASQDVATAMGYLQEQGAVAIGQTSWGPTGFCAVQGANVAEKLKQQVEQQFSGCENLEILVVSARNSGGEVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM01</accession>
    <name>A0A1D3RM01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_105338_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000108">
        <property type="protein sequence ID" value="SCN46528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5466" checksum="CB0E224BF4BA3E3E" modified="2016-11-30" version="1">MGLFIRAVDNRSDTLDFMLSERRDEDAGSSYFCESLFWASQAKQAAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM09</accession>
    <name>A0A1D3RM09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_216531_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000232">
        <property type="protein sequence ID" value="SCN46711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="158" mass="17978" checksum="A55652E6E0284EE1" modified="2016-11-30" version="1">MQTIRGISINTSEYFINGKSDVFRTSKKRKFDNQGRVKLPQYRSIPVPDKVIDDIDLVFDLRRLARLNKEQDQPLWTMSRATTWRMVKGVMARAGIKGKQATSNGLRHGFGIAILSGEKALPLNILRDLMGHSDTKITEIYISAIGAEKRKMVMNAWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM33</accession>
    <name>A0A1D3RM33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">[NiFe] hydrogenase metallocenter assembly protein HypD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_34263_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HypD family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000248">
        <property type="protein sequence ID" value="SCN46732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11740">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002780">
        <property type="entry name" value="Hyd_form_HypD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042243">
        <property type="entry name" value="HypD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042244">
        <property type="entry name" value="HypD_2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30149">
        <property type="entry name" value="PTHR30149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01924">
        <property type="entry name" value="HypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005622">
        <property type="entry name" value="Hydrgn_mat_hypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00075">
        <property type="entry name" value="hypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="334" mass="36988" checksum="0525B742BDF0397E" modified="2016-11-30" version="1">MEVCGGQTHSIIKHGLDQLLPENINLVHGPGCPVCVTPIAYIDKALAIAQQDNVIFCSFGDMLRVPGSQDDLLSLKSQGADIRIIYSPLEALNLAEDNPSKQIVFFAVGFETTAPTCALAIYQAKQRALTNFYMLVCHVRVPPVMQALLDAPDNTVQGFLGAGHVCSIMGYHEYHAISEQYKTPIAITGFEPVDILQGIYQCIQQLEAETYRVDNQFKRVVTEQGNVTAQQLMQQVYIIVDRQWRGMGNIVDSGLALSPEYDAWNAEKYFSVADIQPDEPKACRSGEILKGLIKPVQCPEFNTTCTPEHPLGATMVSSEGACAAYYRYRRYQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM39</accession>
    <name>A0A1D3RM39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00686_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000262">
        <property type="protein sequence ID" value="SCN46751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4599" checksum="6360C36579984BBF" modified="2016-11-30" version="1">MTPPSGAGFFKKYACQIQYEEESDLEGVMDPDNWSVTGISGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM64</accession>
    <name>A0A1D3RM64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-dependent RNA helicase RhlE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_57617_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000193">
        <property type="protein sequence ID" value="SCN46649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="32"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="233"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="399" mass="43838" checksum="49BB386E84A53250" modified="2016-11-30" version="1">MSFASLGLSLPILDAVTAQGYNTPTPIQSQAIPAILEGKDVMAAAQTGTGKTAGFTLPLLELLSKGQRAPANQVRALVLTPTRELAAQVEASITSYGKNLPLKSAVVFGGVKINPQMMRLRQGVDILVATPGRLLDLYNQNAVRFSQLEILVLDEADRMLDMGFIHDIRKILAFLPKQRQNLLFSATFSNEIRQLAKGIVHNPVEMSVSPRNTTAETVKQWICPVDKKKKAPLLTKLINEQNWQQVLVFTRTKRGANQLTRHLEAEGIQSAAIHGNKSQGARTRALADFKAGTVRILVATDIAARGLDIDQLPQVVNFDLPNVPEDYVHRIGRTGRAGASGQAVSLVSADEFEQLSDIERLIQKLLTREIIEGFDPVHSLPESRLDTRPFKAKKPKNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM71</accession>
    <name>A0A1D3RM71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_150907_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000169">
        <property type="protein sequence ID" value="SCN46608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="118" mass="13796" checksum="48CCC5B0F0651918" modified="2016-11-30" version="1">MYRPVQAWQWMVQTRSVPEQDDWVRPDVSEAWLRCLEEYHLPLGNFANWDKHLSHKGLEVDGVKAEHIAEHIEQLSHHFQVFLQEAGVMMVVVAPNGSLLYVAGEQHFPPLKIRETER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM80</accession>
    <name>A0A1D3RM80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">infA</name>
        <name evidence="5" type="ORF">BAZMOX_11087_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000268">
        <property type="protein sequence ID" value="SCN46763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="72" mass="8393" checksum="BFAE3D5299BB0CBA" modified="2016-11-30" version="1">MAKEDQIEMDGTIIDTLPNTMFRVELENGHVITAHISGKMRKHYIRILTGDKVKVEMTPYDLTKGRITFRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM84</accession>
    <name>A0A1D3RM84_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="10">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">secA</name>
        <name evidence="15" type="ORF">BAZMOX_00686_5</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SecA family.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="10"/>
    <dbReference type="EMBL" id="FMJP01000262">
        <property type="protein sequence ID" value="SCN46756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0347">Helicase</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="14">
        <location>
            <begin position="3"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="89"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="440"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="105"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN46756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="617" mass="68923" checksum="1025098F5C2B5889" modified="2016-11-30" version="1">MLGKLVKFVVGSRNDRLVKKKSKIVKLVNKLAEEYGQLTDAALQAKTQEFRERLKQGEKLESLIPEAFATVREASSRVFSMRHFDVQLIGGMVLNDGRIAEMKTGEGKTLMATLAAYLNALPSKGVHVVTVNDYLAARDAEWMGQLYNFLGLTTGVIISDLDHNERKKAYAADITYGTNNEFGFDYLRDNMAFSIEQKVQRGLNFAIVDEVDSILIDEARTPLIISGPTDDSTEIYLKTNEIVPLLTKVERKDGEKEGEETGPGDFTVDEKSKQLHLTESGHEHIESLLVEHGLLEEGASLYEPANIRLMHYLNASLRAHVLFHRDVDYIVQNNEVIIVDEFTGRIMPGRRWSEGLHQAMEAKEGTKIQSENQTLASITFQNYFRLYEKLSGMTGTADTESFELNKIYGLEVVVIPTHRPMTRLDKGDLVYLTAKEKYLAITEDIKDCVKRGQPVLVGTTSVENSELISSILNQSKIKHEVLNAKQHEREAHIIEQAGMPAAVTIATNMAGRGTDIVLGGNMDAQIAALGDSPSQAEIDKVKGKWLDLHERVLQSGGLHVIGSERHESRRIDNQLRGRSGRQGDVGSTRFYLSLEDDLMRIFASDRVAGLMKKLRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM96</accession>
    <name>A0A1D3RM96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_411146_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000302">
        <property type="protein sequence ID" value="SCN46811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="53" mass="6096" checksum="DA31446333822FA8" modified="2016-11-30" version="1">MILFYAHWEIKGGLYQNLPINATEIPQLAYACDRTQLSEEYIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA2</accession>
    <name>A0A1D3RMA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
            <ecNumber evidence="8">6.1.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_224573_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.1.1.15" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000284">
        <property type="protein sequence ID" value="SCN46784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="7">
        <location>
            <begin position="2"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_2b" evidence="5">
        <location>
            <begin position="119"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="HGTP_anticodon" evidence="6">
        <location>
            <begin position="202"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="296" mass="32201" checksum="41AB2A5A104F39A0" modified="2016-11-30" version="1">MVKTLLVEGHSKKGESAEIIALILRGDHTLSEIKAQHIEGVASPLVFANNEQIKAVAHCDVGSIGPKGLATRIIVDRSAEKLADFVCGANETGKHLTGVNWDRDINHYEIADLRDVVAGDPSPCGKGHLEIARGIEVGHIFQLGTTYSKALNATVLNKQGKSQILAMGCYGIGISRIVAAAIEQNNDKNGIIWNDLLAPFSVVIVPMNMKKSVQVAQLAQKYYTQLKALNIEVLFDDRQERPGIMFADAELLGIPHMLIIGDRGIDNGVIEYKERQSGLKQDVNIESVIDFITDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB4</accession>
    <name>A0A1D3RMB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00523_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4472" checksum="F18C38C10D94410D" modified="2016-11-30" version="1">MFKNFKISKEFYDLLEDKILEYGFYFSVDSLKTGVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME6</accession>
    <name>A0A1D3RME6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permease of the drug/metabolite transporter (DMT) superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_03276_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000342">
        <property type="protein sequence ID" value="SCN46875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="147"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="289" mass="31775" checksum="FB9796BCA5DA493D" modified="2016-11-30" version="1">MRIALAFIFIVLLWSTTPLAIKWSAEGSSFIFGVAARMVIGLICILFMLLLSRQPLPWHSKARQTYFAIAVQVYGAMMAVYWGAQFIPSGWVSVIFGLSPFITALLTALWLEERSLTWDKLLAYLLGVGGLALIFSTAIQMSFQSVLGILSVLLAVFLQALSAVWVKRLQAKLPALTQVTGGLIFATPLYLLTWWIIDGVIPTTLPAHSLLSILYLGIIATPIGFALYYYVLTHLAATHVALITLVSPVFALFLGYYLNEEMLTIKIIAGTGLILCALLIHSFVYRKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMH7</accession>
    <name>A0A1D3RMH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RepA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_76314_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000324">
        <property type="protein sequence ID" value="SCN46846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018777">
        <property type="entry name" value="Replication_initiator_prot_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10134">
        <property type="entry name" value="RPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="337" mass="38618" checksum="C009D831AE07D8EF" modified="2016-11-30" version="1">MTEPLLPVRHPQNDLFICDLGDVIPKSDIASMEHPLFTLSTKPDTNIRSYEHNGNTVTIIPSAIGLATIHDKDILIYCISQLMAGINRGQEPSNIIRFKAHDLLVSTNRQTDGDGYKRLNQALDRLSGALIKTNIKTNNEIIDDRFHILDSATIIRENPIDETSRMVEIKIKLSDWLYNAVLGKEVLSINQQYFRLRKPIERRIYEIARKHCGNQKKWHIGLKNLHKKVGSSGNVRLFKQAVKHIIENNHLPDYSLHFDGDNIVFRNKNWEGEISQSSEDRKILLSPETVEKAKKILGREFDVYVVESEWLKWIEGKEVAKTTDGAFIGFCKNKIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ3</accession>
    <name>A0A1D3RMJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine synthetase type I</fullName>
            <ecNumber evidence="3">6.3.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_19409_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000347">
        <property type="protein sequence ID" value="SCN46883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001637">
        <property type="entry name" value="Gln_synth_I_adenylation_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00182">
        <property type="entry name" value="GLNA_ADENYLATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="2">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="208" mass="23053" checksum="244D8356D04AE142" modified="2016-11-30" version="1">MGDNGNGMHVHQSLAKDGVNLFSGDLYGGLSETALFYIGGIIKHAKALNAFANASTNSYKRLVPGFEAPVMLAYSARNRSASIRIPFVNNPKGRRIELRFGDSTANPYLCFAAMLMAGLDGIQNKIHPGDAMDKDLYDLPPEEEKLIPQVAFSFDEALKALDEDREFLTRGGVFTDDAIDGYIDLKMEEVTRLRMSTHPVEFDMYYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ6</accession>
    <name>A0A1D3RMJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_34966_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000335">
        <property type="protein sequence ID" value="SCN46866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="284"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="316"/>
            <end position="323"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="532" mass="58770" checksum="7762C628C6FAC1E4" modified="2016-11-30" version="1">MTETLLTVENLHLSFAGQPVINGISFQINKGETFALVGESGSGKSLAALSVLRLHPTQAYLQADTIQLADIDILRTPESELCQVRGQRVAMIFQDPMSSLNPVMMIGQQIAETIQLHFSMAKKQCTEKVLVLLQQVGIPDAPRRMNEYPHQLSGGQRQRVMIAIALAGEPDLLIADEPTTALDVTIQAQILDLLKSIQQQNGMALWLISHDLALVSNMADRVAVMQSGNIVETANNKAIFSRPQHIYTQKLLQALPNINYQAEQQKPESIALLKLTDFKVHYPIRKGLLKRVVDYVKAVDGVSFTLDAGKTLALVGESGCGKTTLGKGLLSLIPSTSGRVDFHGVDLSTLSREQLRVQRAAMQIIFQDPFSAMNPRMFILDIVAEGIRTLHPTTNKEEIVRQVTEILKQVGLDETALYRFPHEFSGGQRQRICIARALAVKPKLIVCDEPTSALDVSVQKQIIELLKSLQKTQNISYLFITHDLAVVAEIADEVAVMYQGKIVEQGSVEQILRQAQHPYTQKLLSAVPILVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK6</accession>
    <name>A0A1D3RMK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_03276_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000342">
        <property type="protein sequence ID" value="SCN46876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="187"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="374" mass="42645" checksum="633D97E826BA0643" modified="2016-11-30" version="1">MKIVFVADNVDGEKSGGVVSTRRFIDYFKKSDDLTVISTGKVEENKIIFPAFYLPFAKKQMQEMDFLFAWPNKKVLTEAIQDADLVHIQFPFFLGYQALKIARKMHKPVVFGFHVQPENLMWNIGLDFAWLNAFLYRFFIRTFYNKADLVLSPSAFGKEMLEKYAIQTPVEVVSNGLPEQFKPKHCVKEQEFEGRFVILMVGRLATEKRYALVMQAIKQSKFKDKIQLVVTGQGALREELIDLGNSLPNPAFFEYVSQEKLITLFNTADLFIHASDIELEGMAVLEAIGCGLPALISDSEQSASAQFALNEQFLFSAGNLESLIEKMDYWIEHEAELKAAKIPYLEKANVYAFDACAQQARDFYEEVVANKKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML9</accession>
    <name>A0A1D3RML9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_259346_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000386">
        <property type="protein sequence ID" value="SCN46941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="91" mass="10428" checksum="56CC0A42A316B670" modified="2016-11-30" version="1">MDKGGSSENDAPSSKKKKGPRRSKKGNLIIDETHIIQPDEIPENSRFKGYQERVIQDITFQTHNICYRLAEYTTPEGAYDCRSASRWHSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM7</accession>
    <name>A0A1D3RMM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Segregation and condensation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03068_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000379">
        <property type="protein sequence ID" value="SCN46930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01805">
        <property type="entry name" value="ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="270" mass="30698" checksum="BDFE69BA93ED8D3A" modified="2016-11-30" version="1">MSINLVAESRTVTAMVAGQPYLDWPDDLYIPPEALEVFLTTFEGPLDLLLYLIRKQNLDIVNIPIAQITKQYKIYIEVMSNFRFELAAEYLLMAALLAEIKSRMLLPRQVNVEEDEDDPRAVLVRRLQEYERIKKAAEELDEIPRMERDIFIATIDTSNVNVHKPKPEVQLQDIVLALQGVLKRVDQLTHHTITKEALSVRERMAAIMIKLEGSGSFLFAQFFTYQEGRAGVVVAFLAILELSKAELIEILQAEPFGELRIQARVGGGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP7</accession>
    <name>A0A1D3RMP7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_100031_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000391">
        <property type="protein sequence ID" value="SCN46950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018777">
        <property type="entry name" value="Replication_initiator_prot_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10134">
        <property type="entry name" value="RPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="258" mass="29617" checksum="0F126075B043B6B3" modified="2016-11-30" version="1">MDIAVFGLGRKPRFEPIKHKLKDAEIIVQGGTDCGMATIFDYDIFLYMVSFLTNEMNKVRGEIKAGRESYLPLRKIRPSVAELLKYCRRNHGGKNYKLLEKALERLSTTKIKIKHEGKGLRRVGMFSLIGDYTIETQKETGVIMSVSIDIPQWVYDGVVRVDNPTVLTLPKDYFLLDQGNHRFLHRLCRKAAGKGEANYNLQTIYDRSGSTRAFRSWKADFKKSIEVLQKNPLPDYSVTWEKTSGRINIKMVFTGKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ2</accession>
    <name>A0A1D3RMQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II restriction enzyme eco47ii</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_51220_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000387">
        <property type="protein sequence ID" value="SCN46943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019057">
        <property type="entry name" value="Restrct_endonuc_II_Eco47II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09553">
        <property type="entry name" value="RE_Eco47II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="250" mass="29031" checksum="8EC5D92A7E799202" modified="2016-11-30" version="1">MPQYNLGFIDDESIFNHVLETVKKYRFSVNLKEFNKNLIDPIKLTFDAKIYKKNISDIIENEVLRQIDKSNTNHIGYFHQNMFNHFGDGWLVPKNGYDVINEERLIFIEMKNKHNTMNSSSSQKTYMRMQNTILKTPDATCMLVEVIAKNSQDMVWKMRLDGVPVSDDRIRRVSIDKFYKLVTGDAHAFKNLCEKLPLIISDAVDSLDDSIMGNTVFEELGDISPNLMKSIYLLSFEKYEGFNTLEMLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR6</accession>
    <name>A0A1D3RMR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_234244_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000412">
        <property type="protein sequence ID" value="SCN46970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4380" checksum="D08892F9D6163A3E" modified="2016-11-30" version="1">MPMGTGKLLTGNNQLRVRTPADPLYPQEWDDWVKLGLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMU5</accession>
    <name>A0A1D3RMU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Topoisomerase IV subunit B</fullName>
            <ecNumber evidence="2">5.99.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_12860_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="5.99.1.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000440">
        <property type="protein sequence ID" value="SCN47011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="28"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="119" mass="13017" checksum="59D873CAD1E2A6B2" modified="2016-11-30" version="1">MSNTYNAAAIEVLSGLDPVRKRPGMYTDTTRPNHLVQEVLDNSVDEAVAGHASSIEVTLYKDGSIKVQDDGRGMPVDMHPEQNMPGVEVILTQLHAGGKFSNKNYQFSGGFAWRGYLCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW1</accession>
    <name>A0A1D3RMW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_85310_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000294">
        <property type="protein sequence ID" value="SCN46797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026523">
        <property type="entry name" value="PNMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14893">
        <property type="entry name" value="PNMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="SSF57756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="394"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="456" mass="53378" checksum="E6DFB5E13923D480" modified="2016-11-30" version="1">MKSAFQEMTTQVVVAIQTAFRGTKGHTPEQRENVKPSQDIKRAERREPSKSRSYSYNESFSSSEDGTEESDLESLATSQIVRPKQRKSNHTAIARLPAFTGKEKWEVWINRFEAVARLQDWNNKGKLQELLPRLQGAAGDFAFDQMSENTLNSYSKLVNELKNRFGVIENKKTYRVQFNRRNQKTGETVEIYATELKRIYEKAYTNRDARIRQEDLLQRFLMGIGNDKARIHIELNKDPKTIEEAVQEVITFMETTKYPQHDDEQYFNKRRFVRQVTRTEKDTSDWKTGKLNGKRPLTTQKEQKADYGASTCHQSVDMQQIQQMFEKMYEEKRKNEEQASFGIPQGRRHFNTNNNHNTNNDMKRQYPNEHMRNNSFQKEKAQMGQSSQSQPFLCFYCGQPGHYARQCFSNPERRQDKFSQQRNGETLPQRSWNNKKSDEQAVSSHLMGVPPGFSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY2</accession>
    <name>A0A1D3RMY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase associated protein RapA</fullName>
            <ecNumber evidence="2">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00434_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040766">
        <property type="entry name" value="Tudor_2_RapA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18337">
        <property type="entry name" value="Tudor_RapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="107"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="395" mass="45564" checksum="190212B3A9E3A9DD" modified="2016-11-30" version="1">MPDDKIEIEGGNHLIVKSVTEEQGLLRYHALTEDGNIVLVDEMELSHHLQFNKPQDKLFIGQVELGRWFSLRYQTWNYLYQLGKSDVQGLLGARASLIPHQLYIAHEVARRDRVRVMLADEVGLGKTIEAGLILHRRIQTGLSARVMVIVPESLLHQWLVEMLRRFNLKFSLFDESRCLAIDEDNPFLSEQLVLCSLDFFEQNPHRQAQAIQASWDVVVVDEAHHLQWCEGALSHAYLFVEQLAQVTDGLMLLTATPEQLGKKTHFAQLRLLDPDRFHSFELFLEEERQFEPIAQLAEKIVHKHRLSEADKSSLSAYIDQNLCAKFLQNENANDIALDVIDQLIDRHGTGRILFRNSRHVVQGFPVREFYAYPLPPESKESDITYLAWLVEKINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY3</accession>
    <name>A0A1D3RMY3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SLT_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_47467_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000308">
        <property type="protein sequence ID" value="SCN46817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045795">
        <property type="entry name" value="SLT_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19489">
        <property type="entry name" value="SLT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLT_4" evidence="1">
        <location>
            <begin position="2"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="58" mass="6991" checksum="B8314A59C94FA1BD" modified="2016-11-30" version="1">MNQYLAYHEGHGGYKRKSYLKKPWLLKIAKKVNRQAQTFKQQLKGCKAELESKGWFFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY4</accession>
    <name>A0A1D3RMY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Dihydrodipicolinate reductase</fullName>
            <ecNumber evidence="11">1.17.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_174150_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapB family.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="11"/>
    <dbReference type="EMBL" id="FMJP01000453">
        <property type="protein sequence ID" value="SCN47032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="10">
        <location>
            <begin position="47"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="188" mass="20597" checksum="C028C8B8EF02C9A8" modified="2016-11-30" version="1">MQYIELCRLAGKQIIIGTTGYSEEQKVQIAAAAKDIAIVLAPNMSVGVNLSLKLLEMTAKVMGDYTDIEVIEAHHRHKVDAPSGTALRMGEVIADTLGRDLKDCAIYGREGDTGERDRKTIGFSTIRAGDIVGEHTVMFADEGERVEITHKATSRMTFANGAVRAAVWLESQKNDLYDMQDVLGLKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ5</accession>
    <name>A0A1D3RMZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="3">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_04671_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="5.4.2.10" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000446">
        <property type="protein sequence ID" value="SCN47016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_III" evidence="2">
        <location>
            <begin position="2"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="1">
        <location>
            <begin position="62"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="136" mass="14705" checksum="C04A937AD13C2605" modified="2016-11-30" version="1">MELMQQHGSLLGGEGSGHIICLDRTTTGDGVVAALQVLAEVHRTGKSLYALKSEMNKYPQVLVNVKVTQKVDPNSNEVIQKAVKVVEKELGDSGRVLLRASGTEPLIRVMIEGVNEDIVRKHAHELADVVKNAITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN14</accession>
    <name>A0A1D3RN14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type I restriction-modification system, specificity subunit S</fullName>
            <ecNumber evidence="5">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_12464_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000493">
        <property type="protein sequence ID" value="SCN47081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="15"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="225" mass="25624" checksum="93A5747F771CB20B" modified="2016-11-30" version="1">MDAFLSKNFLIDKSTWLKVKLGDVVIEPKESVKDFAIEQIEHVVGLEHIDSEDIHLRRSATMGNSTTFTKKFATNDVLFGRRRAYLKKAAQAKFSGICSGDITVMRAKADLLPELLPFIINNDKFFDYAVKHSAGSLSPRVKFKDLANYEFKLPPKEQQAKLAELLWAMDEVVEKELRLFNVLRRTTQNIFENRVNEAVGEQAFLSDVLVLKKRKVLYLTIGSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN16</accession>
    <name>A0A1D3RN16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSHA biogenesis protein MshM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00434_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="15"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="250" mass="27992" checksum="350E2166EC904C45" modified="2016-11-30" version="1">MVRSLLEEIKAQCEVGLITNTHSAFGDLLTWVLAAFNIESPAVNKAERYRAFVDFITEKSNAGTRVVLIVDEAQNMDIQTLEELRLLSNINTHQEIMLQLVLVGQPELVDKLNQPELVQFSQRISIEYHLNPLSYEETEQYIDFRLKVAGSTEKIFQPSACAALFYYSGGVPRLINNLGDLALVFAFAADKKKINWKTIIDVVSERTTGGIKRFEGKICLSPNIIECAAEAEKLRRALLEATGVDISKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN18</accession>
    <name>A0A1D3RN18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_113293_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000465">
        <property type="protein sequence ID" value="SCN47044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="367" mass="42556" checksum="00821EF48434D094" modified="2016-11-30" version="1">MQASSYSSADINFNPQTSNKPTKFIILLLLATIIPFIAGPLIRSVYSGSDFAQQLFYLVLMFGGYHQGASVYLYFDSDAKKIINQHKWYFYFWPLMISASIMLFYLIDNLWLESYLLQVYAMLTIYHYQKQNIGVYSLLAPTLGSGRMMPVERGLIMGGAVVGMLVFTWPIDRSLFQGTLLSTYKDSIETFSLTLLCVLTLYTVYYISKNYLFSQTRQTQYARAALLLILVTFFWPMFIIEDKQTAFFMYATAHGLQYYVFIAIAAFNGDKIQHLLNTGHLKGVLLRYYNLILFIVLTALLVYIWKELYLLNPPAIFNFSDTEIKRSIFGLASSISLIHYWIDGRIWKIRHNDSREFMRSKFKFGSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN44</accession>
    <name>A0A1D3RN44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribonucleotide reductase transcriptional regulator NrdR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02217_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000520">
        <property type="protein sequence ID" value="SCN47111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4450" checksum="F8B1CDEE7FFE163E" modified="2016-11-30" version="1">MKELIALDHVAFVRFASVYRSFQDVSEFTDMIADLQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN45</accession>
    <name>A0A1D3RN45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_50229_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000519">
        <property type="protein sequence ID" value="SCN47110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="61" mass="6502" checksum="7F3AE8B93CD8967D" modified="2016-11-30" version="1">MKMINKTKFAIGTSLVAGLVTGCANSDTNLFGQEELSSGYMNQADSAKEGGCNKGKGWRVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN59</accession>
    <name>A0A1D3RN59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_11998_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000489">
        <property type="protein sequence ID" value="SCN47076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="206" mass="22250" checksum="C14BF4564DF4451A" modified="2016-11-30" version="1">MFGFISDIFSSKKSSTQAIYRSDENESASSDELTGVAKYLNAHSAVTRGPSSVDKYLQGQVQRSSVAKYVTRQAIAAKQANKTSADAKGVTGVAKYLANNVDAKPVKSGVSKYLATRKVTTVSSVSKYMLKRALEAKNKPEVVRNKPTSVAQYLEDRPKHTTSSVAKYLAKKVSAAKQVAVEAIDEVAEPVVTLTGVERYLKQHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN62</accession>
    <name>A0A1D3RN62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LSU ribosomal protein L30p (L7e)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_28573_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000385">
        <property type="protein sequence ID" value="SCN46938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="5">
        <location>
            <begin position="6"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="61" mass="6869" checksum="14BAD0F8CC15F580" modified="2016-11-30" version="1">MADKKLRVTMIKSSIGRLKSHKACLIGLGLKRIRHTVEVIDTAENRGMINKVSYMVTVEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN72</accession>
    <name>A0A1D3RN72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell division protein FtsL, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_00289_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000434">
        <property type="protein sequence ID" value="SCN46999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00910">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011922">
        <property type="entry name" value="Cell_div_FtsL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37479">
        <property type="entry name" value="PTHR37479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04999">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02209">
        <property type="entry name" value="ftsL_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="90" mass="10570" checksum="0937E59B377AF2D9" modified="2016-11-30" version="1">MLIMERLCVVILLIILLSSGLAVIYAKYNSRLVFIEIQKAEQELDRLEVLWGRLTLEERMLAEHNRVEKIARKTMGLVELERKSIVYIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN74</accession>
    <name>A0A1D3RN74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_109183_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000542">
        <property type="protein sequence ID" value="SCN47141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4165" checksum="9E943A72DCF8096A" modified="2016-11-30" version="1">MSNGIAVLKVQNTVKLHVQNVKKKLVEVADICLLASFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN90</accession>
    <name>A0A1D3RN90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <ecNumber evidence="3">1.1.1.267</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01036_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.1.1.267" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000535">
        <property type="protein sequence ID" value="SCN47133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_reductoisom" evidence="2">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="178" mass="18859" checksum="2F63E092B73ABBAF" modified="2016-11-30" version="1">MKGICILGATGSIGVSTLDVVKRHSDLYRVVALTANTNIDVLYAQCLEFKPEYAVVVNAQKGAEFKAKLVGTVIADMTVLIGSEALVTVATLGHVDSVMAAIVGAAGLLSALAAAQAGKTVLLANKESLVMSGDIFMSSDKRFGAVCCLLIVSIMQFFNVCQLAIRLDMMHLQRVVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN98</accession>
    <name>A0A1D3RN98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_03040_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000555">
        <property type="protein sequence ID" value="SCN47152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="5"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="225" mass="24458" checksum="A187F2A9D01972AF" modified="2016-11-30" version="1">MPDNADALHYLGLIYYQTGDSESAVTLISKAVSISPTHLMHSNLGAALQAQGRHDLAVENYQAAIALKADYIDAYNNLGAALQEQGKLAESIKAFQKALALNTNDASAQNNMGNALLSQGNLKEALGCYRSSLSLNVDNLSTHSNLLLALSYYPQCTPAQYLEEARAFGKKVLAIARPYMVWPAFLADREEKSYELALFQGILKFTLLAISWKISSSILILQGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA3</accession>
    <name>A0A1D3RNA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_04316_3</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000451">
        <property type="protein sequence ID" value="SCN47029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="252" mass="27625" checksum="E611DCC724284299" modified="2016-11-30" version="1">MTHPNQNSSKVRSRGIYLLPNLFTTAALFSGFYAIASAISGRYETAAILIFVSLVLDGLDGRVARMTNTQSDFGAEYDSMADMISFGAAPAIVMYLWSLSSLGQVGLIGAFVHLAGGALRLARFNTQLATQDKNYFQGLPSPAAASLLAGFVWVSEKYQYGAENLPWLVLILTVTTGLLMVSNFRYHSFKDINFKGKVPFVVMIFVMLGFAITLSNPATILCLFFFAYALSGPIVTIVLMRRKRQQSRSNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA5</accession>
    <name>A0A1D3RNA5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rplX</name>
        <name evidence="3" type="ORF">BAZMOX_10545_4</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000565">
        <property type="protein sequence ID" value="SCN47170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="104" mass="11655" checksum="A0E0E9EAED5631AF" modified="2016-11-30" version="1">MQKLKQGDEVIVLIGKDKGKRGRISKFMHEKVLVEGVNRVKKHQKPNPNAGVQGGIIEKEMPIHKSNIALYNSATKKADKVGFKALDNGNKVRYFKSNNEIIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB3</accession>
    <name>A0A1D3RNB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_386658_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000459">
        <property type="protein sequence ID" value="SCN47039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="49" mass="5512" checksum="5FB855236CC3AA12" modified="2016-11-30" version="1">MPPSRTAIAAHFGLANFPVAYCGLKIITSLALRFPDFQRSHWSEPEPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC2</accession>
    <name>A0A1D3RNC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_57089_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000548">
        <property type="protein sequence ID" value="SCN47144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9444" checksum="B2B21C5EEC794D17" modified="2016-11-30" version="1">MLVDYWAEWCGPCKMIAPVLDEIANEYKGKITVAKLNIDDNPTTPAHYGVRGIPTLMLFKDGDIEATKVGALTKSQLVQFIDDNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC8</accession>
    <name>A0A1D3RNC8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="7" type="ORF">BAZMOX_10545_7</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000565">
        <property type="protein sequence ID" value="SCN47173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="131" mass="14055" checksum="CB2FD101B1B30668" modified="2016-11-30" version="1">MSMTDPVADMLTRIRNGQSAGKINVKMPSSKLKVAIAKVLKEEGYISNYSTETNGAHVSMSVELKYYNGKPVIDKVKRISKPGLRIYKSKDELPKVLGGLGVAIVSTSKGVMTDRAARAIGHGGEVLCTVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE8</accession>
    <name>A0A1D3RNE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_104487_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000584">
        <property type="protein sequence ID" value="SCN47211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="78" mass="8969" checksum="995A32F4FE410AC3" modified="2016-11-30" version="1">MKTVTMRIDESVYEMIRQAADGQKRNMSNFVEFATLQYLTSSQYIDQAELNNILNDKPLVENLNSGLQDVKNGDYTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI2</accession>
    <name>A0A1D3RNI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycogen branching enzyme, GH-57-type, archaeal</fullName>
            <ecNumber evidence="5">2.4.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_00619_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000609">
        <property type="protein sequence ID" value="SCN47241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030979">
        <property type="term" value="P:alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037090">
        <property type="entry name" value="57_glycoside_trans_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015293">
        <property type="entry name" value="BE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040042">
        <property type="entry name" value="Branching_enz_MT3115-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41695">
        <property type="entry name" value="PTHR41695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09210">
        <property type="entry name" value="DUF1957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="SSF88688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="3">
        <location>
            <begin position="10"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1957" evidence="4">
        <location>
            <begin position="427"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="529" mass="61452" checksum="CD53050B6B3B92AD" modified="2016-11-30" version="1">MVMQKGFLSIVLHAHLPFVRHPEYDNFFEEIWLFEAITECYIPLIRSLEKLHQDHVNFKLTLSLSPPLISMLSNELLQARYIVHLNKQIELTEKEIIRTVGNPEYQRLARLYRRLYLNTLDIFSQYDSNLLTAFKKFNHLGYLELITCAATHGFLPLLNKSEAAVRSQINIGMETFITHFGFAPEGFWLPECGYYPGLEKHLKNAGINYFFVDTHGIENASEPPKNGVYAPLNCGNDVMAFARDPESSRQVWNSTEGYPGDYDYREYYSDIGFELELDYIAPYILDGHTRINTGIKYHRITGQNLPKDIYQPKQAHYKVQLHAQDFINKRQLQINRLSTEMERPPMIVAPYDAELFGHWWYEGPQWLECVLRLADSNENTLQTVSCADYLKQVAPQQIATPSASTWGDQGYSHFWINESNDWVYPLLHKAATDLEKFVLTLQNSKVNPLQERVLNQAVRSLLLAQASDWPFIMQTGTTVEYANKRITDHLARFNYLLDSIKKNTINERFLSALEVLDDIFPEIDFRSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI7</accession>
    <name>A0A1D3RNI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III</fullName>
            <ecNumber evidence="3">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00619_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.11.2" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000609">
        <property type="protein sequence ID" value="SCN47240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005085">
        <property type="entry name" value="CBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16760">
        <property type="entry name" value="CBM53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM_25" evidence="2">
        <location>
            <begin position="108"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="218"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="458" mass="53032" checksum="209902D997817AAC" modified="2016-11-30" version="1">MGEDKIWHTLSAHYHSLSGNGKEYWSASVNLYLTEELSLPGNIEFNIRYRVLEQEHFLNNNGANYLSEADSGISLIDQSSLQNVGFKNKLRAGQKTIYVTAAIKQSFHAKKVTIHWTTDNWQTIRKTACHFKRQHWPKVLGSHARNPNQYGTQVWTGKIHHAELFKLKYAISCENSEQIVWDNNEGHNYSFQREQLKVLILNLHCYQEENQDEKFSIIAKAIDELNIDIACFQEVAEYWNNGQGDWSSNSAKIINERLSKPYHIHNDWSHLGFDQYREGVAILSRYPLSDHDSLYVSDSHDIYDINSRKVITARVYVPFIGYIQVYSVHLSWLEGGFQEQFQRLSVWAEHKQDATTKATLLCGDFNITACSAGYQQVVDLDVYEDQYLAVNKQGVFNQVFKVHDAQWQDLLADDYRIDYIFMNKNSELKAMSASVIFTDQDYGRVSDHCGYLMTFEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK1</accession>
    <name>A0A1D3RNK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ClpB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_20421_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000639">
        <property type="protein sequence ID" value="SCN47295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="283"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="6">
        <location>
            <begin position="452"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="98"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="544" mass="61157" checksum="A67A0B9DC926E31F" modified="2016-11-30" version="1">MNFWETSDIEKDAALERRFQKVLVDEPSVEDTIAILRGLKECYEVHHGVAITDPAIIAAAQLSSRYIADRQLPDKAIDLIDEAASCIRMELDSKPEVMDKLERRLIQLKIEHEATKKDSDKASQKRLATLNDKIQELGKEFIDLEETWKAEKAAIQGSANIKEKLEQARTELKTAQHSNDLILMSELRYGKIPELEYQLDLASQAEMQEMTLLRNNVTKEEIAEVVSKWTSIPVAKMFEGERDKLLNMEQTLAERIIGQTEAIKAVSNAMRRSRTGLSDPDRPSGSFLFLGPTGVGKTELCKALANFLFDTEDAMIRIDMSEFMERHSAARLVGAPPGYAGYEEGGYLTTAVYRCPYSVVLLDEVEKAHVDVFNILLQVLDNGRLTDGQGHTVDFRNTVIIMTSNLGSALTQELVGEDNYEAMKQAVMEVVGSHFRPEFINRIDETVVFHPLAAEHIRSIAKIQVEHLRTRLFDRNIQLTMTEAALDKISEAGFDPAFGARSLKRAIQQDLENPLAQDILSGKFAAEDTINVDEQEGVLRFIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP0</accession>
    <name>A0A1D3RNP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_158182_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000677">
        <property type="protein sequence ID" value="SCN47335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="125" mass="14002" checksum="182770D527DD187B" modified="2016-11-30" version="1">MLSERRDEDAATAFFKQEINNNGFPDKVVMDKSGANYAGLANINLLLILAGFATMIDLCQVKYLNNIVEQDHRFIKKITKPMMEFKAFHSAQAMIAGIETAPMIRKGQLSEEKIPAYKKFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS8</accession>
    <name>A0A1D3RNS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipid carrier: UDP-N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_140368_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000671">
        <property type="protein sequence ID" value="SCN47332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bac_transf" evidence="2">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="150" mass="17137" checksum="56D7636FC9B0A2F4" modified="2016-11-30" version="1">MYWSDRVGRNNGIFKMPKFRSMKIDTPVVATHLLPGPKSVLIPIGGFLRKSSLDELPQLWSILKGDMSFVGPRPALFNQDDLIALRTEKGVDKLLPGLTGWAQVNGRDELPIPQKVDLDFEYLQKFSFILDLKILWMTFLKVVKRQDVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW3</accession>
    <name>A0A1D3RNW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ribosomal protein S6 glutaminyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_00412_8</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041107">
        <property type="entry name" value="Rimk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18030">
        <property type="entry name" value="Rimk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="108"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="304" mass="33576" checksum="9A4679A9199C9373" modified="2016-11-30" version="1">MGRIAIFTDDPGWHGKQLRLAFAARGYLAEYVSLTECRIIVEEGALPLYIPGFESALPDAVFVRGVPGGSLTEVVLYLDILHALKIIGIPVYNDGHAIERSVDKGMTSFLLQQHQLPTPQTWVLRDRGKALEIAERELSQGYQLISKPIFGSQGEGIRRLEKMTDLFWLAHSQGVYYLQRFVPCAGEGYSDWRVFVVNGKAIAAMRRCGIHWLNNVARGASCEALPLDNVMAELAIKATAALQMNYAGVDIICTREGGYKIIEVNSIPAWRGLESVCEVNMAEVLVDDLLNYCQLEGQGAEAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX3</accession>
    <name>A0A1D3RNX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_345802_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000556">
        <property type="protein sequence ID" value="SCN47157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="59" mass="6689" checksum="DD8E630D99C55E07" modified="2016-11-30" version="1">MRTAIAAHFGLANFPVAYCGLKIITSLALRFPDFQRQYLEQLRKKLLIAVKAGDKVRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX5</accession>
    <name>A0A1D3RNX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_05058_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000710">
        <property type="protein sequence ID" value="SCN47390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="394" mass="43136" checksum="1EA51BCC11E5B279" modified="2016-11-30" version="1">MGINLSDRLSAVKPSPTLAITARAAEMRAAGRDIIGLGAGEPDFDTPIRIKKAAIKAINNGFTKYTAVDGTPSLKQAIIDKFKKDNGFEYNLKQILVSSGGKQSFYNLAQALLNRGDEVIISAPYWVSYPDMVLLADATPVIIETTQAQLFKISPEQLRAAITDKTRLFVINSPSNPTGVAYTLEELKALATVLLEYPDIIIATDDMYEHILWQKGSFVNILNACPELYDRCMVLNGVSKAYSMTGWRIGYAAGPAEIITGMRKVQSQSTSNPASISQVAAEEALHGDQSCIDTMLVEFKKRHDYVVEELNKLPGVECLKTDGTFYVFPNVEKLIAQLDGVNNDLDLAEYFIEKADVALVPGSAFGCPGHIRISIATSMENLQTALERIKRVMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX7</accession>
    <name>A0A1D3RNX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_434309_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000706">
        <property type="protein sequence ID" value="SCN47382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4857" checksum="A386303B125BF4F7" modified="2016-11-30" version="1">MMGFKTFHSAQATIAGIETAPMIRKGQLSEEKIPTYKQFRALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ5</accession>
    <name>A0A1D3RNZ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsF</name>
        <name evidence="8" type="ORF">BAZMOX_04655_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000620">
        <property type="protein sequence ID" value="SCN47259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020815">
        <property type="entry name" value="Ribosomal_S6_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01048">
        <property type="entry name" value="RIBOSOMAL_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="138" mass="15409" checksum="A04B609EBAA2EF65" modified="2016-11-30" version="1">MRHYEIVFLVHPDQSSQVPAMIDRYRATIEGASGAIHRLEDWGRRHLAYPIKKLQKAHYVLMNIECDQATLAELESSFRFNDAVLRSMTIARKAAITEASVIAAETAEQNTSVEKPVVAEVVVVVKEEVVSVAKSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ6</accession>
    <name>A0A1D3RNZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_423209_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000722">
        <property type="protein sequence ID" value="SCN47402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="125" mass="13928" checksum="6B4A8C8AAC395D6A" modified="2016-11-30" version="1">MLSERRDEDAATAFFKQAINNNGFPDKVVMDKSGANYAGLANINLLLILVGFATMIDICQVKYLNNIIEQDHRFIKKITKPMMGFKAFHSAQATIAGIETAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ8</accession>
    <name>A0A1D3RNZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_117817_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000691">
        <property type="protein sequence ID" value="SCN47366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4302" checksum="C96F1080A3760EFC" modified="2016-11-30" version="1">MTKKFWGCADGPASFNAELSEIGGNIISIDPIYNGVRNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP33</accession>
    <name>A0A1D3RP33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_09742_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000759">
        <property type="protein sequence ID" value="SCN47443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="207" mass="24093" checksum="F9E82571EEB2F1BA" modified="2016-11-30" version="1">MNEQKQVKSKWNVDAALNHIYINEIMFVAMVFLIFLGEVIIEVFDRPGIFYWLLMTPIFCFFSILSEKTKAQATGKEIKHLYHYQFLYWGSAFIAVLLVFLSWHAEAIKASAAGIVIHIILAHTVFLSGIVLGFRFYLIGFLLFCTAALTILMQTTFGIDLLFAIPILWLGFYWEKTHLFPTLKRKSDFVKEMIEDQDYNRRVEGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP62</accession>
    <name>A0A1D3RP62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_115430_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000783">
        <property type="protein sequence ID" value="SCN47481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5185" checksum="776CAE98B9A77C5F" modified="2016-11-30" version="1">MNDSTQSTIHIPQLYVLHSRAILALRLCMRVPFKMYVLIPGMGVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP65</accession>
    <name>A0A1D3RP65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_102902_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000635">
        <property type="protein sequence ID" value="SCN47288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="265" mass="31073" checksum="169067961B9DA5AB" modified="2016-11-30" version="1">MDCIVTIQPALIKQKDGSYKAFFPSVTEELIEESLKKILTDQNYGIHDPYKTETWVKFSLYMVQKELKKRNKSRSLDQIKAAIQIMSQCIIMISKGKKEIWKGAILQDLVTVDREEYIEDTGALHAARLPLFISHAIDKLEYRQFNIDRHMQLKTQLSRWLYKRFVHRYKQASMIDTYHFMYSTVKAESRYLEGKTERNNRKKMLDALEELKGQGILMSYEVRETKEGRKIIDVKYTVTASLDFRTEQKAANAATKNRQLGLVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC4</accession>
    <name>A0A1D3RPC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_34354_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000813">
        <property type="protein sequence ID" value="SCN47541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="78" mass="8685" checksum="7B6F356CBF62F25F" modified="2016-11-30" version="1">MKHILKAVFITFLIISLSACETGMFIRGSHSHHYNDYNQPINWGYTAGDPILGAGYYGNFYPSYGQYVIHQGEGAIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE9</accession>
    <name>A0A1D3RPE9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ribonuclease</fullName>
            <ecNumber evidence="12">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BAZMOX_02807_0</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the RNase HII family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="12"/>
    <dbReference type="EMBL" id="FMJP01000837">
        <property type="protein sequence ID" value="SCN47580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 12 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="2"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SCN47580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="114" mass="12865" checksum="047E024E2F3A2007" modified="2016-11-30" version="1">MNILQASLLAMKRAVESLAVQPTWVQVDGNQYPDIDYPGETIIQGDLLVAEISAASILAKVYRDSEMSTLDVLYPGYEFSKHKGYPTKLHKEKLLSLGLTEQHRRSFSPIRQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH0</accession>
    <name>A0A1D3RPH0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_258626_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000848">
        <property type="protein sequence ID" value="SCN47593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="152" mass="17080" checksum="31D19458A59695D1" modified="2016-11-30" version="1">MNERLVNCTPLLVLKIVGVLTSRAFSSAPIFRPILKERFSSKYRLIIGVINMSTKRKSHSARFKARVALEAYKGDKTAAELISTHKISSCQISTWKKCLVAGAVQLFKSGRAKAVDEETLTSPLYEEIGRLKVELDWLKKSERILLSLRDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH7</accession>
    <name>A0A1D3RPH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infC</name>
        <name evidence="8" type="ORF">BAZMOX_13876_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4 5">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the IF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000682">
        <property type="protein sequence ID" value="SCN47347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="6">
        <location>
            <begin position="63"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="151" mass="17341" checksum="70478D3928043CD6" modified="2016-11-30" version="1">MPEGQGGIMSLMDAKRLAAEANMDLVEVSPNADPSVCKIMDYGKFIFEQNKKMQVAKKKQKQIQVKEIKFRPGTDIGDYNVKLRNLIKFLEEGNKTKITVRFRGREMAHREIGMALLKRVEKDLEEIAVVEQFPKMEGRQMIMVLGPKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI3</accession>
    <name>A0A1D3RPI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_148500_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000830">
        <property type="protein sequence ID" value="SCN47564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4666" checksum="E61F3164DFA6473F" modified="2016-11-30" version="1">MGFKAFHSAQATIAGIETAHIIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK8</accession>
    <name>A0A1D3RPK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hypothetical nudix hydrolase YeaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_90784_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. PCD1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000699">
        <property type="protein sequence ID" value="SCN47377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009132">
        <property type="term" value="P:nucleoside diphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000059">
        <property type="entry name" value="NUDIX_hydrolase_NudL_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01293">
        <property type="entry name" value="NUDIX_COA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="39"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="242" mass="27906" checksum="88859B52635BC0BC" modified="2016-11-30" version="1">MLYVLCYFTETEISKADVRERFSQHDFRMKERIDIPPIFDRASVLIPLFQVDGEWRVLLTVRSKHLRSHSGLVAFPGGKQDSVDMDDIETALREADEEVGLDPGSVEIVSVLHPSYVRPNILVTVVVGIIPSDFKPAINEKEVHRVFSLPLRRFLQDDFTTQQFEVAGNQVQTYFFSDEIDGNRIVTWGFTSHYCMIAAVILFQNYEKRIYGYSDKYVTLDCLWPGISFTNYLLSNYKTAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ1</accession>
    <name>A0A1D3RPQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_334460_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000779">
        <property type="protein sequence ID" value="SCN47478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4348" checksum="25BE8E77CD2D8F64" modified="2016-11-30" version="1">MSMFVLLGWARGSVARIIENEARLVFRHNYPAKAINCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS5</accession>
    <name>A0A1D3RPS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0145 protein BAZMOX_06203_2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_06203_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0145 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000808">
        <property type="protein sequence ID" value="SCN47539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00338">
        <property type="entry name" value="UPF0145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="PTHR34068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="SSF117782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="108" mass="11453" checksum="93E086E83C98EDD6" modified="2016-11-30" version="1">MQFSTTPDIPGKIITENLGIVAGNVVQSKHVGRDLMAGLKSIVGGEIAGYTEMLADARDTAIERMVDEAKKRGADAIVNVRFTTSAIMANASEILAYGTAVKLQSQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT6</accession>
    <name>A0A1D3RPT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LppC putative lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_03410_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000969">
        <property type="protein sequence ID" value="SCN47755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007443">
        <property type="entry name" value="LpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38038">
        <property type="entry name" value="PTHR38038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04348">
        <property type="entry name" value="LppC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="643" mass="72474" checksum="4EB819D244EBB05C" modified="2016-11-30" version="1">MKQYIELSLILCVVLMTSCSSLSKGNRALDLGSQSISQQADQLYAIGEYKKAASLYQSLAKRPSRQQNIFRLKTAFALFKSGFDGQAKVYVESIRPADLSLEWRNQLYLLHAQIDLSAGNAELAINQLQLIQPFALTRNKQLEYRRARAFAFALTGQLEASARERIILGDYLLGDEKTQNSISILEVLSLLPVHVQERQLNLQKYDIYSGWVELASIMRKFNKGSLGFNLALDDWMQKYTQHPGRSLIASGYFSSAIVNIQDINEIAVFLPESGPYVTHAQAVKEGIMAAYYQHQLDAQRPNLHFYDTQSKDIVALYHEAIADGAQLVIGPLNKQLIGQLAAGVTFSVPVLALNYVEDLFKVNLYQFALSPLDEVQQVTNQARFEGHENAIILTPNTVEGERLATYFKNAWNDLEGNILDIQTFARNAKDFSLPVKQLLNINESQYRIQMLSKLVTNIESNPYRRQDIDVIFMIAPSKVARLINPQFYHNRAASVAVYGLSRVYSGQAAPRKDIDLEGVEFCSIPWLFDQAYQGDLDKRTLQKTWEQFPRSFLSLIAFGIDAYNVVPHLNKLDSIQYQGATGGLSLNAVNRIERRLICAKFKQGEVSLIDTAENIPVDFKDSIPELLLERGLFVKPEEGLSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV1</accession>
    <name>A0A1D3RPV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I restriction-modification system, DNA-methyltransferase subunit M</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_21397_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000944">
        <property type="protein sequence ID" value="SCN47721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004546">
        <property type="entry name" value="Restrct_endonuc_T1M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00497">
        <property type="entry name" value="hsdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="281" mass="31730" checksum="F30EFC8E88B6BAD9" modified="2016-11-30" version="1">MQAKKHFDAHIIEEGFWGQEINHTTYNLARMNMFLHNINYDKFNIMLGNTLIEPHFNDDKPFDAIVSNPPYSVKWIGSDDPTLINDERFAPAGVLAPKSKADFAFVLHALNYLSSKGRAAIVCFPGIFYRGSAEKKIRQYLVDNNYVETVISLAPNLFFGTSIAVNILVLSKHKTDTKTQFIDASQFFKKATNNNLLTDKHIEQIIALFDSKDDVAYLAQCVEHQSITDNDYNLSVSAYVEAEDTREVIDITQLNAEIKTTVSKIDKLRSDIDAIVAEIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV3</accession>
    <name>A0A1D3RPV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_44560_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000915">
        <property type="protein sequence ID" value="SCN47676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4704" checksum="C8604D523B44990A" modified="2016-11-30" version="1">MVKYRLTYYKTLKISHNLFSNPNMLSIDNWCGDVKPMAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ7</accession>
    <name>A0A1D3RPZ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_196227_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000928">
        <property type="protein sequence ID" value="SCN47692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4847" checksum="521F313B1611E952" modified="2016-11-30" version="1">MMGFKAFHSAQATIAGIETAHMIRKGQLSEEYIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ8</accession>
    <name>A0A1D3RPZ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ORF">BAZMOX_13384_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000985">
        <property type="protein sequence ID" value="SCN47770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="13"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="188"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="92"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="491" mass="56023" checksum="8EAE57A967254D19" modified="2016-11-30" version="1">MKNKKTFKPCDLVIFGALGDLATRKLLLCLYQLDKANLLEPDTKIIGVDRFADEGNLLLKAANTCLEKFLKEERDLLVWERFSARMSYLQMDLTQPDEYKQLAKVVDKEKRRMINYFSVPPFLFKAICQGLKLSGALTPESRMVMEKPIGYDLESSKEINDAVADVFTGDQVCRIDHYLGKETVLNLLALRFANSLFITNWDHNTIDHIQITVAEEIGIEGRWGYFDQSGQTRDMMQNHLLQILTFIAMEPPVSLDADNIHYEKIKVLKDLRPITVKNVADKTVRGQYAAGQIKGVAVPGYTEEEGANMESGAETFVAVRVDIDNWRWAGVPFYLRTGKRLPAKHSEIIIQFKALPHNIFKDSFEQLPANKLSIRLQPDEGVDVEILNKIPGIDERIKVQENKLDLSFSEAFKGSHIVDAYERLLLEAMRGHSTLFISREEIEQAWTWIDSMQNAWQETHNTPQPYPAGTWGPEAATTLLARDGREWENDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ17</accession>
    <name>A0A1D3RQ17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00594_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="380" mass="41796" checksum="6E69694DDAF00937" modified="2016-11-30" version="1">MERNEAMSFILKLLKLMLEKDGSDLFITAGFPPAMKIKGIMTPISKQALSANDAKSLTQCIMNDKQLKEFEETKECNFAISPAGLSRFRVNAYVQQGSQGLVMRTIANEIPSFETLGLPPILKDLIMAKTGLIVMVGGTGSGKSTSMASMLDHRNENSYGHIITIEDPIEYVHKHKNCVIMQREVGVDTDDWEVALHNTLRQAPDVIVLGEIRDKEIMNFGIEFAQTGHLALATLHANNANQAIDRILGFFSTETQVKLMQDLSLNVRAIISQRLIKTVDGGRCAAIEILINTPLISDLIAKGDVSGIKPIMAKSRELGMQTFDQAIFSLYQQGKISYEEALRNADSANELRLQIKLASGEDNASNGLSLQSTDDHEDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ20</accession>
    <name>A0A1D3RQ20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_72554_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000998">
        <property type="protein sequence ID" value="SCN47790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="294" mass="31434" checksum="FD68652CC5E88F13" modified="2016-11-30" version="1">MHNPNQQTGFTLVEMLMVILIIAATTKIVAVSMEDFGFAARYEHTISRLDTIRQAIIGNPKRTVNGQPDISGFVADMGRLPDNVRELFQSFVCINTSSNTVLPDTPAQCIDANEVPTYLTTPCSDSTQTTQAACEALSAPNNTWVGLQLDVVNNSGLAFGWNGPYLSVSDNPNNTDTFTDGWGNESANNYGWVTCLWDDIAGGGLANNLPNDTDADGLADCSNPPGYPNYTIYSLGKNGTGDVNADGATACDSGSVNDYDGDCNSTILEEDYTVDIRNGINVLIRKESSNSNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ46</accession>
    <name>A0A1D3RQ46_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="8" type="ORF">BAZMOX_04315_5</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000822">
        <property type="protein sequence ID" value="SCN47557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="90" mass="10211" checksum="2584818FBCB0FF76" modified="2016-11-30" version="1">MPRSIKKGPFIDHHLQKKIDDAVSSNSRKPIKTWSRRSMITPEMLGLTIAVHNGRQHVPVLVSENMVGHKLGEFSPTRTYKGHLADKKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ47</accession>
    <name>A0A1D3RQ47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_88045_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000979">
        <property type="protein sequence ID" value="SCN47766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920269" evidence="1">
        <location>
            <begin position="30"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="252" mass="27338" checksum="7BCBF367B376B37A" modified="2016-11-30" version="1">MFKKPKLDLSVATALLALSSLAVAPQASADDMASLQARIAKLEKQEAERQTTGGGNMIYFRGGYARTNNDRFGDILTDSIGLGGSKNGEKDGWYVGAGLDLVLSNDFFGFEDSIEVLGDIMFEYKEFDNTNLDIQALPFLVNTTINPKRISEQGSVKVSQFTLTASPKVKFMRGSKFRPWIIPVGLAIHVISPPSDGVTVLEPGMHFAVGADYNVWHNIFVGADARYNLTFGDLDGVDLNGFTTGAYVGFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ64</accession>
    <name>A0A1D3RQ64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_121048_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001028">
        <property type="protein sequence ID" value="SCN47840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5602" checksum="C0E1C2727C4D1D4D" modified="2016-11-30" version="1">MISVLSFCGKPFHDILFSGQKAEILQVKIAKTKGNKGGKGIKRKQSIGKWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ65</accession>
    <name>A0A1D3RQ65_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 6">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsL</name>
        <name evidence="8" type="ORF">BAZMOX_24983_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4 6">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 4 6">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4 5">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000836">
        <property type="protein sequence ID" value="SCN47577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 5 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="124" mass="13565" checksum="A20486430DA2F4FD" modified="2016-11-30" version="1">MATINQLVRKPRARKAEKSNVPALEACPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGAEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHVVRGSLDTSGVASRKCGRSKYGTKKPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ68</accession>
    <name>A0A1D3RQ68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] synthase, KASI</fullName>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_01376_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01001010">
        <property type="protein sequence ID" value="SCN47804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="4"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="406" mass="43101" checksum="E12523A380049961" modified="2016-11-30" version="1">MKRIVITGLGIVSSIGNNSEEVLASLQEGRSGITFAEDYQELGFRSHVRGAINIDLDDFIDRKVKRFMGDGAAFNYIAMQQAITDSGLEESDVSNVHTGLIMGSGGPSTSNLVAAADILREKGIKRVGPYMVTRAMSSTNTACLATPFKIKGINYSITSACATSAHCIGNAMEQIQLGKQDIVFAGGGEEVHWTMSVLFDGMGAMSSKYNDTPESASRPYDEARDGFVISGGGGVLVLEELEHAKARGAKIYAELTGYGATSDGYDMVQPSGEGAIRCMQQAMATVDAKVDYINAHGTSTPVGDTRELEALRQVFDAEAMPYITSTKSLTGHALGAAGVNEAIYSLLMMKNNFISASANITSMDPGAEGMPIVATRKDDVTLNTIMSNSFGFGGTNASLIFQRYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ74</accession>
    <name>A0A1D3RQ74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_113592_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000841">
        <property type="protein sequence ID" value="SCN47587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="10254" checksum="B145243F9C825D05" modified="2016-11-30" version="1">MLNKLNIELTKSRSRHSNDNALAESKNASVVRKKFDYSHIEQHWADKLNNFNREHLPLFLTITVPAISQRRLPTIREKKENNITMIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB0</accession>
    <name>A0A1D3RQB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FIG138056: a glutathione-dependent thiol reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00742_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000881">
        <property type="protein sequence ID" value="SCN47627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="80" mass="9024" checksum="7818E32F06663A9B" modified="2016-11-30" version="1">MHGLTPEQLQIFIERAGWKSVLNKRSTSWRQVDEGQKADLNAEKAAVLMLANLTLIKRPVLVAGEQLFIGFNAENYQTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB6</accession>
    <name>A0A1D3RQB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphomannomutase</fullName>
            <ecNumber evidence="2">5.4.2.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_07852_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="5.4.2.8" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000955">
        <property type="protein sequence ID" value="SCN47739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_IV" evidence="1">
        <location>
            <begin position="109"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="171" mass="18772" checksum="068D2A3A4260F691" modified="2016-11-30" version="1">MQAMTSQTSVVGYEANGGFLQNTPIQLNNKTLAALPTRDAVIVPLCLLLQAKQLGCSISALLKTLPPRFTYSDRIKNFPSELSQSILGQMQTGELTQDAAVLTQLFTGKIERAVAFDYTDGVRITLANDEVVHFRGSGNAPELRCYTEADSDSHAEALNQLCIKQMHEWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQF0</accession>
    <name>A0A1D3RQF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_265192_1</name>
        <name evidence="3" type="ORF">BAZMOX_538603_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000415">
        <property type="protein sequence ID" value="SCN46973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01001089">
        <property type="protein sequence ID" value="SCN47921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="4"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="5041" checksum="0D419F2FB6544E01" modified="2016-11-30" version="1">MNDYQTVPELRSGLKRYFEFYNQERLHQSLDYQTPSDVHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQG4</accession>
    <name>A0A1D3RQG4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uma2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_45097_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000948">
        <property type="protein sequence ID" value="SCN47728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012296">
        <property type="entry name" value="Nuclease_put_TT1808"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008538">
        <property type="entry name" value="Uma2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05685">
        <property type="entry name" value="Uma2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uma2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="57" mass="6361" checksum="F73AC3337CD3E126" modified="2016-11-30" version="1">MSATKEHALISAEEYLDAELKNDRKHKLINNQVYAMAGASANHKRIAGNIYRQFGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQH1</accession>
    <name>A0A1D3RQH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02007_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001073">
        <property type="protein sequence ID" value="SCN47896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="169" mass="19706" checksum="2D494B90199F61F4" modified="2016-11-30" version="1">MIKHKHITEPDAFGYQVRIVRRGKESSRYFSHKLWGNKNKSIAAAIAWRDQMLVVLKGSRTRFLKPPKNKTTTGLTGVSRTIKYDRRKDKSYLCYTVFWVCNGKSKNKTFQVGNVETISADDELHAFRTARLFRSCYEYAIDYDAHFDDSVFAGWKKKRIYDDLGMMVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQK1</accession>
    <name>A0A1D3RQK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_132670_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000982">
        <property type="protein sequence ID" value="SCN47768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4260" checksum="84E59A8C07B0FF72" modified="2016-11-30" version="1">MRPSISGTADVIHCLLIYSLGSIKFLFSEKNIFSIEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQQ7</accession>
    <name>A0A1D3RQQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type I restriction-modification system, specificity subunit S</fullName>
            <ecNumber evidence="5">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_02029_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01001039">
        <property type="protein sequence ID" value="SCN47858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="24"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="244"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="437" mass="50595" checksum="EA7AED8E1EA25BC3" modified="2016-11-30" version="1">MIQEVYRRYEDYKKTDSLWYDETPNHWQTGRVKDFVVFNTTIKTPINFDENSLVEFVPMTNVDDELGKIKEFNFVPLKEVSSGYTKFRNGDVIFAKITPCMENGNSAIVAGLKHNICFGSTEFMVFRASRKLTNKYLRYFLHNELFRRNAEPFMKGTAGQKRIGSHYMAIHFFSLPPIPEQKSIADYLDTKTTQIDKKVHLLTQKSAHYSKLKQSLINETVTRGLDKTVPMKDSGIEWIGDIPEHWGVSAITNITSTISIKNHPKEELLSVYRDYGVIIKSMRDDNHNKAGANLSNYKLVEAGYLVINKMKAWQGSLGVSEFRGIVSPAYITCKTDKKIVERSYLHHLLRCRNYINEYNRLSYGVRVDQWDMRYDDFKYVPVLLPPKKEQKSIADYLDDKTAKIDTIVKTINTQIEHLKELRKTLINDVVTGQIKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLD4</accession>
    <name>A0A1D3RLD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Similar to amino acid transport protein (Partial length)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04903_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000068">
        <property type="protein sequence ID" value="SCN46480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="7671" checksum="0F86AC6309DE720C" modified="2016-11-30" version="1">MEGTSHLIWSTLFGAIGLGFFTYGTRQKAIVPLCTAVTLFVFPYFIENIYALVFTGMTLVILPYFVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLH8</accession>
    <name>A0A1D3RLH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">General secretion pathway protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00699_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000100">
        <property type="protein sequence ID" value="SCN46520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="134" mass="14812" checksum="A0C63417EDDAD7F9" modified="2016-11-30" version="1">MTSKRQLQAGFSLLEILIAFSILALSLGILLNIFSGGLRRTIVFEEYQQAVIIAQAKMAAAGVELPLDEGQKQGQVLEKYNWSLIMQPLNTDDVAAASEAMGVQVYEVISRVQWMAGDNDRLVELITLKLSKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-06-17" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLJ0</accession>
    <name>A0A1D3RLJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_61653_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000104">
        <property type="protein sequence ID" value="SCN46526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="5"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="61" mass="7265" checksum="0932F81BC5F94F11" modified="2016-11-30" version="1">MTINGMVNRREFEVRLARVVDSAKRERDSHALCFLDLDQFKELMILVVMWQVMSYCGKWVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL5</accession>
    <name>A0A1D3RLL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_75130_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000162">
        <property type="protein sequence ID" value="SCN46595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920247" evidence="1">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="71" mass="7869" checksum="BF98EA228C517FA9" modified="2016-11-30" version="1">MLKKYSLILFLPLILMTGCSGEDNKPTAAKSSTELPVFNEQVKALEKAKEVEKMLQAGMDKQKQAIDEAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ1</accession>
    <name>A0A1D3RLQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome P460</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_10816_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000144">
        <property type="protein sequence ID" value="SCN46574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032033">
        <property type="entry name" value="Cytochrome_P460"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038142">
        <property type="entry name" value="Cytochrome_P460_sp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16694">
        <property type="entry name" value="Cytochrome_P460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920235" evidence="1">
        <location>
            <begin position="23"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome_P460" evidence="2">
        <location>
            <begin position="36"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="168" mass="18395" checksum="C94DB8189AC7F962" modified="2016-11-30" version="1">MKKVSHLLLLSSLICLPQISYAKQEIAAANNIEYPKHLTNWRIIGTSLRNDNNTQRAILGNAIAIKAARAGIKKINWPKGAILAKLVWKNETLPTWQAATVPGDFVHAEIMVRDAKKYAATGGWGFARWTGLELTPHGKDSSSAQACFDCHQAASGTDYVFTQPAKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ5</accession>
    <name>A0A1D3RLQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_75130_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000162">
        <property type="protein sequence ID" value="SCN46593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="35"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="91" mass="10416" checksum="DE4ABFC211D89306" modified="2016-11-30" version="1">MSDLKKYISKRKESDKDFSLNFDEGYQAFKIGLMLKEARENAGITQEELAVRLSTKKSAISRIENHAEDVKLSTLEKFASSLGKNIEIRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT2</accession>
    <name>A0A1D3RLT2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="9">Kdo transferase</shortName>
            <ecNumber evidence="3 9">2.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 9">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_08412_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="3 9"/>
    <dbReference type="EMBL" id="FMJP01000063">
        <property type="protein sequence ID" value="SCN46468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_N" evidence="10">
        <location>
            <begin position="33"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="428" mass="48759" checksum="36D27847F214547E" modified="2016-11-30" version="1">MYYFYVALFYLLLPLLLVFRYFKGLKWQNFNARYNEALGFYKQKHAQQVIWLHAASLGEVEAAHVLIEYLRKNYPYKVLVTTGTEPGYDRVRALQGDQVEHVYLPYDMPGTVERFIKHFQPKIAIIMETEIWPVLFAKCKQHEVPLFIVNARLTEKSSKGYLKLKSFLAKIFAGISGVAVQTEVDARRYQEIGVLAEKITVSGNIKLDMPIAEALRDNMAQVKQELFPNRQVFVVGSTHAGEDEIFLQAYRRLKPKFPELLLVLVPRQPKRTFEIKQLCAKNKLSVLARTEHKPCDSVTDVYLVDTLGELKLMYALADFSFVAGSMVPVGGHNIFEPILLGVPVMFGPYMKNVELLAKQLLDAQGAIQCATEVDIVQAVTKMLEEPQEKRRLISHAQDFVAKNNGAMDRTIALIDPFLRAHKATHLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV6</accession>
    <name>A0A1D3RLV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_03224_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000131">
        <property type="protein sequence ID" value="SCN46559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014976">
        <property type="entry name" value="Cap4_SAVED"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08878">
        <property type="entry name" value="Cap4_SAVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="243" mass="27863" checksum="BDF764C96962942E" modified="2016-11-30" version="1">MLSAWAKHFRNHYCLDTEIDFLRGKRSRRDYLNNIKFPCSTSKLGPGIRAGDFGEVLVADYLQWLLGFCVPRVRWGSKNIRDESPKGSDVIGFRFHKKEDTSQKDVLIVFETKTKFSGSRKNRLQDAINDSAKDHLRIDESLNFIKQKLFEKKEIEQAQRIERFQSPVDMPYKETYGAAAIISDECFDAEELASADCSKISKSAKSQEFFPHPNGDSLVLLVIKGLSMMDLVHELYRRAADEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV7</accession>
    <name>A0A1D3RLV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_10024_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000213">
        <property type="protein sequence ID" value="SCN46685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="58" mass="6938" checksum="D9195CF134849A67" modified="2016-11-30" version="1">MPYDEFPWFAEQSIKSIINVEEISDNHFYWPDLDVDLTLDMIEHPERFPLKAKNIEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW4</accession>
    <name>A0A1D3RLW4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_13546_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000077">
        <property type="protein sequence ID" value="SCN46498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="80" mass="9095" checksum="57468FD03E7889B1" modified="2016-11-30" version="1">MTILNVTEARSKLYKLIDETAITHQPITIKGKRNNAVLVSEEDWNAISETLYLSSVPNMRESIQNGLKESIESCSKELDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM00</accession>
    <name>A0A1D3RM00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_317629_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000218">
        <property type="protein sequence ID" value="SCN46690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="PTHR10293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="3"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="69" mass="7843" checksum="E622547820B01BD6" modified="2016-11-30" version="1">MQACNAKYGSFNIFEDQEVREALKEYSQWLTYPQLYIKGELVGGCDIIMDLYNKGELQKMLAAADSVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM05</accession>
    <name>A0A1D3RM05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_04516_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000219">
        <property type="protein sequence ID" value="SCN46693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="225" mass="24458" checksum="4B8700D1E672C1DA" modified="2016-11-30" version="1">MLLLLRDAGLIPEDHWQVYLPLLTTSMAMIIPFVIIAEKKRKMKAVFVGAVATLVLADLSLFYFNDSLYTLIAGLWVFFCGFNLLEATLPSLISKTAPGNLKGTAMGAYSSAQFFGAFLGGTTGGWIYGEYGANYVFLFCAVAAGLWLIVALFMNAPQYLANLLVSTDDIAADKLADFLADILTVTGVASADFQSSENVVYLKVDNAQLDKDKLQYLLTQWSGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM06</accession>
    <name>A0A1D3RM06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonuclease PH</fullName>
            <ecNumber evidence="2">2.7.7.56</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_18123_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.7.56" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000225">
        <property type="protein sequence ID" value="SCN46700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase_PH_C" evidence="1">
        <location>
            <begin position="15"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="97" mass="10545" checksum="E91200DD2431906A" modified="2016-11-30" version="1">MLKQKKIKKNPLHGQVASISVGIYNGIPVLDLDYKEDSNAETDMNVVMNDAAAFIEVQGTAEGHAFHQEELNAMLALAKSGITNLLAKQSIALTNHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM59</accession>
    <name>A0A1D3RM59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ORF">BAZMOX_172134_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000255">
        <property type="protein sequence ID" value="SCN46744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="182" mass="20413" checksum="403C7F4606E39A0D" modified="2016-11-30" version="1">MSFINVKPGKDVPSDINVIIEIPAYSDPVKYEVDKDTGALTVDRFMGTAMQYPANYGYVPHTLSDDGDPVDVLVITPHPILSGSVIRCRPIGVLKMSDEAGEDAKILAVPVQKLTQYYNKIETYLDFPEADLDKIAHFFEHYKDLEKGKWVKIEGWEGIESAEAEIISSIERYNNMAKKPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM74</accession>
    <name>A0A1D3RM74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VacJ-like lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_13356_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MlaA family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000290">
        <property type="protein sequence ID" value="SCN46791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007428">
        <property type="entry name" value="MlaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30035">
        <property type="entry name" value="PTHR30035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04333">
        <property type="entry name" value="MlaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01805">
        <property type="entry name" value="VACJLIPOPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="233" mass="25646" checksum="08F29F0C1CF78B94" modified="2016-11-30" version="1">MVPHTDPVDPWEGMNRDIMQFNDKLDKDVLKPLAKGYQWITPEFMDVGITNFFSNLRDIGVSVNDFLQAKPKQGSMDIARFVVNSTVGVAGFIDVATLIDLPKHDEDFGQTLGVWGVPMGPYFVLPFYGPSSVRGVGGRAGDMALHPLTYTVLFANPAVGWGAVGARTLDVIDERADFLGAEAAASEAAVDRYLFFRSAYIQRRKYLVNDGAAQPLDLEGIDDESLYDGLEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM75</accession>
    <name>A0A1D3RM75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_97609_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000137">
        <property type="protein sequence ID" value="SCN46567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4867" checksum="47622834C28C32B9" modified="2016-11-30" version="1">MRPKYNVIFHFGEGIGIRRAILPDETLWTPVANAENQGNGALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM76</accession>
    <name>A0A1D3RM76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_63815_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000283">
        <property type="protein sequence ID" value="SCN46782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="120" mass="13620" checksum="AB008FDB5B55171D" modified="2016-11-30" version="1">MAKDREHLSIENDQIDLEDLVSPPQAPPSEEEYKKMQKVGEKLGFVDRSSKIKKTKKRTPYIIQHNSKMRIGMKELLSDLTAHIGAKSDQETLELGILALIEKEGVKGFLKKFKALIKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM83</accession>
    <name>A0A1D3RM83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Outer membrane protein assembly factor YaeT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_02677_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000206">
        <property type="protein sequence ID" value="SCN46669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071709">
        <property type="term" value="P:membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01430">
        <property type="entry name" value="OM_assembly_BamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023707">
        <property type="entry name" value="OM_assembly_BamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF23">
        <property type="entry name" value="PTHR12815:SF23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006076">
        <property type="entry name" value="OM_assembly_OMP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03303">
        <property type="entry name" value="OM_YaeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011260467" evidence="5">
        <location>
            <begin position="23"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="27"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="95"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="178"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="269"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="350"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="795" mass="88587" checksum="5D883F0F7482CF60" modified="2016-11-30" version="1">MKFKFLFSLLFVLLSISSVVHSDETGFVVKDIQVSGLQRISVGTVFNYLPVNVGETLLNKDIAPAIRALFKTGFFKDITLQREGNVLLVIVQERPSISEINIEGNEDLSTEDLLTALKTIGLSKGKVFNRQILDKVEQELMRQYFSHGKYSVKIDTEILELERNRVNISINISEGAVSKIKSVNIVGNKVFAEDDLLKLFELQTSGWLSFYTKDDQYSKQKLGADLERLRSYYLDRGYINFTIKSTQVSMTPDKKDIYLTINIKEGDLFTLDKVKLSGNLVVDPEELIALLQVGPGEIFSRKAATQTSKAISDRLGEEGYAFANVNMVPDIHNDEKLVDMTFFVDPVNRVYVRRIGLQGNTKTRDQVLRREMRQMEGAWASSTKIERSKARLNRLGYFENVGIETPVVPGTRDQMDLNYSVTEKSSGNLMAGIGYSQTQGVIYNASITQDNIFGSGKRVSINFNKSNVSTLYSLGFTNPYFTRDGVSLGYNLLYKSTNANQANISNYLTDVISGGVNFGFPINENQRLNMGFNLKHTTLKEGVNPPPELPVWINANGDKFLTLPLSIGWMRDTLDRPTFPTTGSQQRLSGLVALPGGDLTYFKVSAKDQHYFSVAKDLVFKIMASAAYGDGFGSTDQLPFFENYFAGGVNSVRGFRDNTLGPRDHCNGTCSLTDGNTPRPYGGNFKVLANTELIFPVPFMSDIDSIRLSVFFDMGTVQGPYIQYHADDPTCTPSDTSCYTRFNSGISFGDFRYSTGVAAQWLSPFGALQVSYGIPLNDKPGDQLQAFQFSFGSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM89</accession>
    <name>A0A1D3RM89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter, ATP-binding/permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_24970_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000277">
        <property type="protein sequence ID" value="SCN46774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="51"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="287" mass="31932" checksum="BF7EEE4903374B76" modified="2016-11-30" version="1">MAPVQEVLGIQYSFYGAKAALERINRMQTLQQEPIYPALINPFLNKKTVSLRIENLHFRYNIEKDEILSGINLSVKAGEKIALVGASGGGKSTLIQTLNGLYPVTSGTIYYDNIPMNKIGLDVIREHVVTVLQHPTLFNDSIRENLTLGKAATDAELWQALEIAQLKETILGLEKGLDTIVGRQGMRLSGGQRQRIAIARMIIARPSIVVLDEATSALDTETEHKLHQALNDFLKGRTTVIIAHRLSAIKQADHVYVFDEGKICEQGEHNKLINQNGLYAKLYGEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA1</accession>
    <name>A0A1D3RMA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chromosome (Plasmid) partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_63815_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000283">
        <property type="protein sequence ID" value="SCN46783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009744">
        <property type="entry name" value="VirC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07015">
        <property type="entry name" value="VirC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="237" mass="25407" checksum="96A7398B17E226C1" modified="2016-11-30" version="1">MPVIVFASSKGGAGKTTATIVLACELARQAKEKGLNIALIDADPNQHSAAWAQKGGRPDNIKLFEKVTSESILEAIEEAQSKAAFILVDLEGVASSAVIGAMSRADLVIVPCQASQNDAREAMKTIKTIKYSSKVSGRNIAYSVLFTRLSAAIITKTGRHLAADFDSSGVDLFVCSLIDREAFKSVFSFGGTVNELEVNTKREQASIEKAAENARVFAEEVKRKLKASIEERKVVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA6</accession>
    <name>A0A1D3RMA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_172123_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000304">
        <property type="protein sequence ID" value="SCN46812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920238" evidence="1">
        <location>
            <begin position="18"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="191" mass="21579" checksum="43B6495CB9FF1856" modified="2016-11-30" version="1">MKKILLAVLLLPLLASAATLDLLKFYGSGVPRFKGKVYTDEKVLDEVVEVQVIDEWLNEIIKADIAKQFVGGYLSIVDTGWEDSECSGKIVIDQGSPVADNLFMGKLFFLQEDREDGNHDTLFSADLSITDGVLNMVMRWEEYEDAGMPENPKVYLLARNKDGHWQNFYNGYVDTVACDVYLTVAHDKRYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC5</accession>
    <name>A0A1D3RMC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartyl-tRNA synthetase @ Aspartyl-tRNA(Asn) synthetase</fullName>
            <ecNumber evidence="8">6.1.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_49011_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000292">
        <property type="protein sequence ID" value="SCN46796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="142"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="400" mass="45930" checksum="B16C99602AD1591E" modified="2016-11-30" version="1">MRTHKCGELNKENLGEAVELCGWVHRRRDHGGVIFIDLRDRAGLVQVVFNPESEETFALAESVRSEYVLRVEGVVRDRLEGTVNANMATGEVEVLVNHVEVLNESETPPFPIESDIEVNEEMRLRYRYIDLRKTAMLRNMTMRRDVTRNVRNFLDAQDFFEMETPILTKATPEGARDYIVPSRTHPNNFFALPQSPQLYKQLLMIAGMDKYYQIVRCFRDEDLRADRQPEFTQLDIETSFMNEDSIMAVMEDMMRGLFKDVIDVDLGDKFPQMTYAEAMSRFGSDKPDLRIPLELVDIAEEMKDVDFKVFSGPANDPKGRVAALRVPNGSTLSRKDIDVYTKFVSIYGARGLAYIKVNDRNGGIESLQSPIVKFAPAKVWQAVLEKTRRTNGRFNFLWCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD8</accession>
    <name>A0A1D3RMD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_263740_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000181">
        <property type="protein sequence ID" value="SCN46627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011518">
        <property type="entry name" value="Transposase_36"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07592">
        <property type="entry name" value="DDE_Tnp_ISAZ013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="146" mass="16940" checksum="43B26BC75DBC8FF4" modified="2016-11-30" version="1">MKKFYDSLCEKDKRRYAAIESEKLPRGGVNYISELLDCDPKTIRRGQRELSELEFDATGIRKPGGGRKKKIFTPEYCGIDQCFLDILQEHTAGDPMNSSIRWTYLKPREIVSELLKKGYSVSRNIVRYLLKKHKYLNPASITHNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF2</accession>
    <name>A0A1D3RMF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Excinuclease ABC subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_55192_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000216">
        <property type="protein sequence ID" value="SCN46688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UVR" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="2">
        <location>
            <begin position="41"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="394" mass="43771" checksum="ACC6E94BE1D793B4" modified="2016-11-30" version="1">MDTLAQHLEFEQAALVRDQISQLRTILEKNYVSGESGDVDIVACATKAGIACVQIFFIRNGQNLGNKTFFPKISKEYTPENILQAFIPQYYLDKNVPHELIVSHRPEEIELLAEVLTEYAGHGVNISSNVRSDRAKWLQIASVNVENALTTKLADKQGIYARFLSLQEELGCQEIPKRLECFDISHTQGDYTVASCVVFDREGPVKSAYRRFNIEDITPGDDYAAIYQAVSRRFKRLVKGEHEAPNILFIDGGKGQVHQAEKALAELAVNSVMIVGVAKGPDRKAGMENLILPGQELPLDVTPNASALLLIQHIRGEAHRFAITGHRARRGKATKKSVLETIAGLGPKRRQILLKQFGGMQGISRAGVEALCSIEGISRQLAQRIYDTFHHQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMJ2</accession>
    <name>A0A1D3RMJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_121363_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000210">
        <property type="protein sequence ID" value="SCN46677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4758" checksum="0387306F558FE941" modified="2016-11-30" version="1">MLGFKAFHSAQATIAGIETAPMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP8</accession>
    <name>A0A1D3RMP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP-glucose dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_94197_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.1.1.22" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000421">
        <property type="protein sequence ID" value="SCN46975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="3">
        <location>
            <begin position="14"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="121" mass="13957" checksum="D309B76CE4B81644" modified="2016-11-30" version="1">MLKKRLHVQDSNVLIMGLTFKENCPDLRNTRVVDIIKELETYGVNIHVYDPWVDPEEAVVEYGIKPIATLEEGRFDAIVLAVAHEQFKQMDIKQVRALGKPDSVIYDLKYLFPADLTDERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMQ4</accession>
    <name>A0A1D3RMQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation/multidrug efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_261914_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000316">
        <property type="protein sequence ID" value="SCN46839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="203" mass="22108" checksum="7DDD175FAA3D8E33" modified="2016-11-30" version="1">MEASFFTDFKQSYPDISLSFEGEIKEGPLTRSSMRKSMLMGLVGVFILLSLQFRSYIEPVLVMANIPLAFIGVIFGHLIMGLDITMPSLLGFVSLAGIVVNDSILLVEFVKKHIQADITPHEAAAKASSERFRAVFLTSLTTAVGLTPLLFEQSSQAQILIPLATSIVFGIISSTLLVLFVTPCLYAILEDFGVAKMTKSDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR0</accession>
    <name>A0A1D3RMR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00824_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000397">
        <property type="protein sequence ID" value="SCN46953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="132" mass="14236" checksum="4E3CB0618DA1E433" modified="2016-11-30" version="1">MEKQIIQTNAAPQAIGTYSQAIKVDNTVYLSGQIPLDPATMEIVSGDISVHIRRVFDNLQAVAQASGGDLADIVKLNVFLTDLAHFPIVNEIMGQYFTQPYPARAAVGVAALPKGVGVEMDAIMILRAPEYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMV4</accession>
    <name>A0A1D3RMV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_94197_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000421">
        <property type="protein sequence ID" value="SCN46976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="334" mass="37805" checksum="137D1BDD00B9987C" modified="2016-11-30" version="1">MKIMVTGTAGFIGNHLAIKLLERGDEVIGIDNLNDYYDVNLKLARLDRIKDHPNFTDVRADISDRERMEALFKEHQPQRVVNLAAQAGVRYSIENPHAYIESNILGFLNILEGCRHNNVEHLVYASSSSVYGANESMPFSVHDNVDHPLSLYAASKKSNELMAHTYSNLYNLPTTGLRFFTVYGPWGRPDMALFLFTKAIQEGKPIQVFNYGKHRRDFTYIDDIVEGIIRTLGHVAQPNPDWSGKNPDPGTSKAPWRVYNIGNQSPVELMDYIETLEKFLGKKAEKVLLPLQPGDVPDTYADVEALVQDVGYKPNTTIEQGIEKFAAWYNSYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW4</accession>
    <name>A0A1D3RMW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron binding protein IscA for iron-sulfur cluster assembly</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_10865_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000426">
        <property type="protein sequence ID" value="SCN46986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="107" mass="11344" checksum="C717CAB8F3737E80" modified="2016-11-30" version="1">MAVVLTESAAKQIQKQIEKRGKGLGLKLGIKTSGCSGFAYTIDYADELQSGESVFETFGVKVIVADENLAALDGLVLDYAKEGINEAFKFNNPNVKGTCGCGESFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW8</accession>
    <name>A0A1D3RMW8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbonic anhydrase</fullName>
            <ecNumber evidence="2">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02303_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000354">
        <property type="protein sequence ID" value="SCN46899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43175">
        <property type="entry name" value="PTHR43175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="192" mass="21147" checksum="F2C02FD7A1F02AB3" modified="2016-11-30" version="1">MSKILNEVLLANREYTAGFDKANLAMPPARQFAILTCMDARLDPAKYAGLSEGDAHVIRNAGGRASDDAIRSLVISYKLLGTREWFVIHHTDCGMETFTDNIMRELLSTSLKTASVDDTGWHDCCEGSGSTEGNYINWLTIEEQTASVLEDVTRIRNHPLVPSDIPIYGYIYDVKSGSLVEVPEATTVGQCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY1</accession>
    <name>A0A1D3RMY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_72910_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000476">
        <property type="protein sequence ID" value="SCN47051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920259" evidence="1">
        <location>
            <begin position="21"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="420" mass="46270" checksum="E1BA7F26A29D3DCE" modified="2016-11-30" version="1">MKTLKLIVPLILLSAISAKANAFPDTLEKLFVENDSTGFIPDELDFTTTQKKDIFPDKIAQEFGVNLGESLYDDYSPVEVAPVGGLIVVDDPSGNNDRVYSLDPVEPAPAGGSVVVYDPSGNNDGVYSFDPVEPTTPAGGSVVVYDPSGNNDGVYSLDPVEPTTPDKPLPPSVPGAPVEESYMDTPFNSVFLSPKEIGLVDEYNFGSCGDNFADTKAESNYVAEYGDVISEIEVYGYKNVLVTYFPEGTYGSEYDYADALGARLLTDIPVDGKETVTIKIAEEVNDYVRAYDDLTPYMLIQCSNKVVEKKITQEWNMIREWNVLHDFAGGFLVVPQLLVVETGKLYFATFISTDEGMRLFNYQEIPASENGNKSAKFYKDEGLLIVPAYIDGDESSNYEIYGAEFKTENGDDYKFHKAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY8</accession>
    <name>A0A1D3RMY8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_06086_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="FMJP01000338">
        <property type="protein sequence ID" value="SCN46868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004620">
        <property type="entry name" value="MTHF_reductase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00676">
        <property type="entry name" value="fadh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="6 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="281" mass="31573" checksum="7AE0A6AE907D94BB" modified="2016-11-30" version="1">MMTKKNKADLFSFEFYPPKTEEGAVNLEKVHQELAQLNPDFFSVTFGAGGSTRDKTYDTVVKIQKNGVSAAPHLSCVASTKENILEILQNYRQHGVSKIVALRGDLPSGMMSAGEFRYANELVEFIRKETGDHFQIHVAGYPEIHPQASCAQTDFDNFKRKVDAGANAVITQYFYNAEAYFYFLDKCEKSGIDIPIVPGIMPITNYSQLFRFSDMCGADIPRWMRKTLEGFGDDRESIVAFGEDVVSKLCQELLDNGAPGLHFYTMNQAKPTLAVWNNLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ0</accession>
    <name>A0A1D3RMZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenosylhopane nucleosidase, HpnG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01616_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000313">
        <property type="protein sequence ID" value="SCN46827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017831">
        <property type="entry name" value="Hopanoid-assoc_phosphoryl_HpnG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03468">
        <property type="entry name" value="HpnG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="235" mass="25524" checksum="4B3CF9191CD825E1" modified="2016-11-30" version="1">MITGILVALPEELHTLTKTKIKQGECITMTKNIIIILSGAGPENARIAAQTLIDQGAKQLISWGCAGAIAPYLKAGDLLIPESIYTQSQRLIATHTSWSKKIIANLANSTKYYTGTLLESDSVVALTQAKNRLHQSTRALAIDMESGAVARIAQEAQVPFIALRSIVDPANLDLPNAIHYAMTKSGVVSIPKLMLYLCHHPHELPRLIKLGLNFHAASKTLKHLAQQLPQITQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN13</accession>
    <name>A0A1D3RN13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_35689_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000508">
        <property type="protein sequence ID" value="SCN47095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="350" mass="40026" checksum="9E6B0BD690400078" modified="2016-11-30" version="1">MKIVSLFSGAGGLDKGFEAAGFQTIWANEYDKDIWETFERNFPNTALDRRSIRDVPSNEIPDCDGIIGGPPCQSWSEAGTLKGIEDKRGQLFFEFIRILRDKNPKFFLAENVSGMLAERHSEALKNIKILFSESGYDLSFSLLNAVNYGTPQDRKRVFFIGIRKDLNFTFEFPEPLKNKQFLKDIITDIQDSALPAKEKQKTNGDKCYLPNHEYMIGGFSSIYMSRNRVRSWDEPSFTIQAGGRHAPIHPQAPKMKFIEPNKRIFVEGKESLYRRLSIRECARIQTFSDNHIFYYSNLMAGYKMVGNAVPCNLAYCLGKSLKQQLIEYQAHNKKITPFPVAKDHAISVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN19</accession>
    <name>A0A1D3RN19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_02303_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000354">
        <property type="protein sequence ID" value="SCN46898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="294" mass="33374" checksum="076DD98123BBF141" modified="2016-11-30" version="1">MDKLKNMQVFCRIVELGTFVAVAREMDVSAMMISKYMRSLENSLGVTLINRQTRQLHVTELGLSYYRQCKQLLEDLNDIESSVTQSGKIVKGVLKINVPIDFGGLYMVPVIDAYQKECPDVDVLMSLNNARINLRAGNFDISIVVTDKLDQGVVAREIAQTSLCTYASPSYLKQYGCPKTVEDLEQHKCLHYLDTPHAYVWVFQKDNKRIDIRPKWSFASNNGRALCQAAALGMGLIRAPALSVRSYVQSGELVEVLDSYKIPKLSVYATYLRRNYYPTKMSTFIDFLVNYFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN24</accession>
    <name>A0A1D3RN24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cas5fv_helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_359238_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000502">
        <property type="protein sequence ID" value="SCN47091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045374">
        <property type="entry name" value="Cas5fv_helical"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20158">
        <property type="entry name" value="Cas5fv_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas5fv_helical" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="81" mass="8881" checksum="048319AA04984F31" modified="2016-11-30" version="1">MDSAKTKAGGISGISKRGFTTKDFMSRFTTGDNRRATARLMIDFGTPVTKIDSPRGESIVPQYALRPLQLRTKAATLKLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN33</accession>
    <name>A0A1D3RN33_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_36330_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000361">
        <property type="protein sequence ID" value="SCN46908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TonB_dep_Rec" evidence="1">
        <location>
            <begin position="2"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="276" mass="31604" checksum="A4B0DD48A9F18967" modified="2016-11-30" version="1">MPNDWANYNFGYARKNRAPSLHELYPWSTSPMPMTMIGWFGDDNGNGNGYVGNINLKTETAHNITFTSEFFDPTGNDDWSIKLTPYFSYVENFIDADLCQTCKQPKNGFSYLRMANHNALLWGIDVSGQVNLYDSKQLGQFSSKSIMSYMRGRRMDGGNLYHMMPFNLKWSIDHKLNGWQNSIEMQFVDAKDEVQAIRNELQTASYILLNMKTSYQWQYGSVDLGVDNILNKQYYAPLSGVYIGDQYPMTLVSSRPNTQNLAGQGRSVYVGFTLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN35</accession>
    <name>A0A1D3RN35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_12464_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000493">
        <property type="protein sequence ID" value="SCN47083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="82" mass="9463" checksum="90C0000A401679FC" modified="2016-11-30" version="1">MQRISITIEDDLKAELDNIAAKGERAAFISQAIQKAIDDWHKQQALKKILNFKPYKINRDSVEVLREVRDGRVQQVLDASRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN50</accession>
    <name>A0A1D3RN50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_129519_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000513">
        <property type="protein sequence ID" value="SCN47102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002560">
        <property type="entry name" value="Transposase_DDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032877">
        <property type="entry name" value="Transposase_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01610">
        <property type="entry name" value="DDE_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13542">
        <property type="entry name" value="HTH_Tnp_ISL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_ISL3" evidence="2">
        <location>
            <begin position="99"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_ISL3" evidence="1">
        <location>
            <begin position="162"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="416" mass="48040" checksum="783BBB07A7046BA3" modified="2016-11-30" version="1">MFFMITELFQQALHINSPWLIKSIDFNAEEKRLDIQIDFKRGSTFEDPDAGDDEVKEYKAYDTVQKNWQHLNFFEHECHLHARVPRIKRDDGKVRLIPTPWEGKVSGFTLLFEALLIQLCKAMPVHNVSDLTGVSDHKIWRVLDTYIELAKMDEDYSDISILGMDETSIAKGHDYITLFVDLEERKTLHISAGKDHKTVVDFVEVLEAKQGDRSAIKQVSCDMSPAFIKGVKENMPEAEITFDKFHIIKLINEAVDQVRREEGSYTPILKGNRYIFLKNESNLTEKQKIIKEELSMAKLNLKSVRALQIREAFQQIYVAESTEKFEGLLNNWYYWATHSQLAPIVKVAKTIKRHWDGIVSWKKSQINNGILEGLNSVLQAAKRKARGYKMQHFKTIAYLLTGKLDFSKINANCLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN60</accession>
    <name>A0A1D3RN60_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine acetyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_10865_3</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000426">
        <property type="protein sequence ID" value="SCN46989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000441">
        <property type="entry name" value="CysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="209" mass="22384" checksum="5B228958A5755323" modified="2016-11-30" version="1">MLHRISHQLWAKGFKFIARVIAHAARWFTGIEIHPGAVVGQRFFIDHGMGVVIGETTIIGDDCTLYHGVTLGGTSWNKGKRHPTLKNGVVVGAGAKILGPIEVGENARVGSNSVVLKAVPDGATVVGIPGHVVGAKDKKVTEIANKMGFDAYGTTVDSPDPVAYSINHMLEHIQAMDKQMCAMKQAMKQAGIECTSEILSKLDDCELDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN61</accession>
    <name>A0A1D3RN61_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Na(+)-translocating NADH-quinone reductase subunit A</fullName>
            <shortName evidence="2">Na(+)-NQR subunit A</shortName>
            <shortName evidence="2">Na(+)-translocating NQR subunit A</shortName>
            <ecNumber evidence="2">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NQR complex subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NQR-1 subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nqrA</name>
        <name evidence="4" type="ORF">BAZMOX_02303_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NqrA family.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000354">
        <property type="protein sequence ID" value="SCN46897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00425">
        <property type="entry name" value="NqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008703">
        <property type="entry name" value="NqrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022615">
        <property type="entry name" value="NqrA_C_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37839">
        <property type="entry name" value="PTHR37839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05896">
        <property type="entry name" value="NQRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11973">
        <property type="entry name" value="NQRA_SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01936">
        <property type="entry name" value="nqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0915">Sodium</keyword>
    <keyword evidence="2" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 2" id="KW-0813">Transport</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NQRA_SLBB" evidence="3">
        <location>
            <begin position="263"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="450" mass="48527" checksum="CAA987116962D171" modified="2016-11-30" version="1">MQFITKEGLDLPITGTPKQTIEEGNPVSSVAILGMDYVGMKPKMMVAEGDKVKLGQALFEDKKNPGVIFTAPGAGTVTAIHRGEKRVLQSVVIALEGGDEESFQAYSAKELLDLTAEQIKQNLVASGLWTSFRTRPYGKTPTLDAVPRSIFVTAIDTRPLAADPAVIIKERSDDFTNGLAIIAKLTAGKTYLCKATGADIPAGNIESVEVAEFAGPHPAGLPSTHIHLLDPVNADKSVWHLDYQSVIAIGALFVSGRLNVERVVALSGPAVTEPRLIRTRLGASTDDLVKGQTTDDENRVISGSVLYGHEATGWSAYLGKFSNQISVLREGRERELFGWIVAGKDKYSAINIYTSSCDRVANRLFPLTTDKNGSNRAIVPIGVYELVTPLDILPTPLLKALVVGDTDQAQLLGCLELDDEDMSLYTFVDPGKHDFAPVLRANLTKIEKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND1</accession>
    <name>A0A1D3RND1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent RNA helicase RhlE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_133797_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000439">
        <property type="protein sequence ID" value="SCN47008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="218"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="382"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="391"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="421" mass="46687" checksum="6AEF8040A865F758" modified="2016-11-30" version="1">MSFKQLDLCAPLLLAITEQGYEQATPVQEQSIPVILQGRDILAGAQTGTGKTAGFALPILQLLHNQERPAKPHPVRALILTPTRELAMQVYESFKIYGKHLPLFSEVVFGGVSTHAQIKRLQQGADILVATPGRLLDLLNQKKVDLSQVQFFVLDEADRMLDMGFILDIRKLMSVLPKQRQNLLFSATYSQEIKILAGQLLNDPVEVAIARENVAADTVTQSVYAIKKENKRELVSWLIGHNNWQQVLIFVRTKHGADRLAKQLIKDGLRCDALHGDKSQGARSRALENFKSGKISVLIATDIAARGLDIDQLPHVINFDLPAQAEDYVHRIGRTGRAGTSGEAISLVDAEEAYLLAAVEKLLGKKIPRVADTGYATVSLDVINKPKAQPRQNQRQHRNKNGQKKQTAGARHRRPRSNTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND2</accession>
    <name>A0A1D3RND2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00840_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000567">
        <property type="protein sequence ID" value="SCN47182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="13"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="143" mass="16115" checksum="FDA4871119ACE60A" modified="2016-11-30" version="1">MRIQGINDRRILDEVVEKSLRGAAIWDEVKDRLQDNALGISGGQQQRLVIARAIAIEPTILLLDEPSSALDPISSLKIEELINELKETYAIVIVTHNMQQAARVSDYTAFMYMGDLIEFGDTNTIFTNPEKKQTEDYITGRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF4</accession>
    <name>A0A1D3RNF4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA pyrophosphohydrolase</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">(Di)nucleoside polyphosphate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rppH</name>
        <name evidence="3" type="synonym">nudH</name>
        <name evidence="6" type="ORF">BAZMOX_01012_4</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. RppH subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000580">
        <property type="protein sequence ID" value="SCN47203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03671">
        <property type="entry name" value="Ap4A_hydrolase_plant_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00298">
        <property type="entry name" value="Nudix_RppH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022927">
        <property type="entry name" value="RppH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Nudix box" evidence="3">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="177" mass="21063" checksum="345552BD06A38F3F" modified="2016-11-30" version="1">MIDSKGYRANVGIILCNARGQVFWAKRARMNSWQFPQGGIENNENPEQAMYRELCEETGLKPEHVQILGRTRYWLKYKLPEKYIRRNSHPLCIGQKQVWYLLKLVGQEADVILDQHKKPEFDDWQWVEYWEPLKSVVYFKRKVYRKAMMELGAFLMLPSVDVDAESYLSNDNMSEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG3</accession>
    <name>A0A1D3RNG3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD(P)HX epimerase / NAD(P)HX dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_00619_5</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000609">
        <property type="protein sequence ID" value="SCN47245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="149" mass="15821" checksum="605258F33AB613B3" modified="2016-11-30" version="1">MIDADALNLLVDFPVYSEQWILTPHPGEAARLLQCSTADILQDRFKAVRALQTKYGGVCVLKGAGTLICDDKKQVYVNTTGNPGMAAGGMGDVLSGTIGALLAQQYDLLEAAKIGVYLHGLAADKAAVSLGERGLRATDVVQYLREVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH3</accession>
    <name>A0A1D3RNH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_26544_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000590">
        <property type="protein sequence ID" value="SCN47222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4539" checksum="3B70A1B415DC2D16" modified="2016-11-30" version="1">METLSAINITVILAHNQIKTVQVLYCINVLVEKFECASWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI5</accession>
    <name>A0A1D3RNI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Signal peptidase I</fullName>
            <ecNumber evidence="3 6">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_01012_7</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 6"/>
    <dbReference type="EMBL" id="FMJP01000580">
        <property type="protein sequence ID" value="SCN47206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="8">
        <location>
            <begin position="43"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="226" mass="26022" checksum="954D072E6DDA78A3" modified="2016-11-30" version="1">MDFDFSFFLFSASLVTGIIWGGYYYHLKRTNTPYIEENEPLIVEYARSFFPVVFVVFLLRSFIAEPFRIPSGSMMPTLLIGDFILVNKFTYGIRIPVINKKIIDISEPQRGDAVVFRYPKNPSVDYIKRLIGLPGDHIRYIDKQLYVNDQPIKYVSLGRYEGMGQGKSMTGAELLQEDLLGVKHKILINHRAPNIKGTFIVPQGHYFMMGDNRDNSNDSRYWGTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNK3</accession>
    <name>A0A1D3RNK3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsR</name>
        <name evidence="6" type="ORF">BAZMOX_04655_4</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000620">
        <property type="protein sequence ID" value="SCN47260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="76" mass="8676" checksum="A6B659886BF9490A" modified="2016-11-30" version="1">MARQMRRKKHFAFGTPGEANAIDYKNIEMLNEFVTETGKIVPSRITGTSAKHQRQITNAIKRARYIALVPFCDAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL8</accession>
    <name>A0A1D3RNL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00271_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000628">
        <property type="protein sequence ID" value="SCN47263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920250" evidence="1">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="131" mass="14562" checksum="391B6B121996162A" modified="2016-11-30" version="1">MKKALLLTLCVLAFPALAAEKTQPSGATWTGSNLSEATIKQVQTDKYNYTDCIYKEAQKQGYKKIDARVATDAVMKQCEKELSKIRTTFIGNGVPPIIADRYLKKTRIDMTRKILKSLIFAEAARKSGATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM2</accession>
    <name>A0A1D3RNM2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase Obg</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">obg</name>
        <name evidence="9" type="ORF">BAZMOX_04234_3</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000632">
        <property type="protein sequence ID" value="SCN47281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="8">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="7">
        <location>
            <begin position="160"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="213"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="284"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="315"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="349" mass="37871" checksum="CE0CB936763AB4E6" modified="2016-11-30" version="1">MKFVDEAEIRVEAGDGGNGCVGFRREKYIPKGGPDGGDAGDGGSVYLVATENVNTLVDFRFHSVHRAERGQNGMGQQRTGKKGDDIYVPVPPGTEVHDKKTQEKLGELTKVGETLLVAQGGFHGLGNTRYKSSINRAPQKASSGTKGGHRILQLELTLIADVGLLGMPNAGKSSLIRAVSSAKPRVADYPFTTLVPNLGVVSVDERRSFVIADIPGVIEGAAEGAGLGLQFLKHLARTKLLMHLVDVAPYDEMDSPVEAARKIINEVEKWSEDLAGKPRWLILNKIDKLDSAEQEVRCQAIIDELQWQAPVYQISALKSEGTRALMFDIMAFLEEQTALAKLEAEDEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP1</accession>
    <name>A0A1D3RNP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <ecNumber evidence="1">1.17.7.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04655_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.17.7.4" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000620">
        <property type="protein sequence ID" value="SCN47256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="54" mass="5999" checksum="888DC7FDFE35D6B8" modified="2016-11-30" version="1">MGQYEKCTENGAIYLVETPEDVKTVKVNNPENLAYVTQTTLSMTDTQVMVDALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ2</accession>
    <name>A0A1D3RNQ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_61359_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000647">
        <property type="protein sequence ID" value="SCN47302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013162">
        <property type="entry name" value="CD80_C2-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08205">
        <property type="entry name" value="C2-set_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="SSF48726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="172" mass="19211" checksum="3528B447469A9DFE" modified="2016-11-30" version="1">MTTVTITPAGDINIVDIIEGETQTFTCTTDSSRPAAWIQWYIGGQNVTNQAAPQLPQQDGDMLISSSSLVYTGSDVDQNKVIFCEAVNIEGRKKAKSTEKSVYIQCKYYLPYSCTGLCLLSADELLILRVDFDTIVQDRSFIATFIKLLICNVHRKSKSYYSNVIIKISFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU5</accession>
    <name>A0A1D3RNU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_21766_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000587">
        <property type="protein sequence ID" value="SCN47219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920271" evidence="1">
        <location>
            <begin position="33"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="2">
        <location>
            <begin position="79"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="238" mass="27040" checksum="66BE9798B62D2FD1" modified="2016-11-30" version="1">MKNNVNIQRRKLLKLAGISAAALATFPSLLNAKTMRVGRHASPDFNPDIEIKLTGEVKYVPIFNGPQTRVWKVIGEVLKGPAKTITNEKSYLAPTIRLHKGQKVRIYSNNELPSATILHWHGLHVPSEMDGNPMYAIDHGETFVYEFEILNRAGTYWYHAHTHSLTAKHVYSGLAGFFLVSDNEEQSLKLPSGEFDVPLVIQDRNFDQQNQLKYAGGMMMKMHGFFRRSDFGEWYTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV1</accession>
    <name>A0A1D3RNV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_00412_6</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006346">
        <property type="entry name" value="PGPase/MupP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01449">
        <property type="entry name" value="PGP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="215" mass="23863" checksum="399D7BAC37132AF4" modified="2016-11-30" version="1">MDGTLLNTAPDLTTALNKALENFQFPSVSAAAITPYISYGAAVMIEQSLEQACSDSLKAEILEWLLDYYENHIADHTYLYSGIPELLANLEERNIPWGVVTNKRERMTHPLMNALNLTQRAASIICGDTTAHSKPHPEPMLTACQQIQVTPEECLYIGDAAHDISAGKAANMKTLAATYGYLRPDDQPQDWGADALVHHPDDISHWIKNYTYAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV2</accession>
    <name>A0A1D3RNV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_385711_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000540">
        <property type="protein sequence ID" value="SCN47137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="10634" checksum="A1EA244D7F2E4B81" modified="2016-11-30" version="1">MDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIIEQDHRFIKKITKPMMGFKAFHSAQATIAGIETAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX0</accession>
    <name>A0A1D3RNX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS2020, hypothetical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_363592_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000705">
        <property type="protein sequence ID" value="SCN47381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="125" mass="13868" checksum="BC05939D3EAD4FF3" modified="2016-11-30" version="1">MLSERRDEDAATAFFKQAINNNGFPDKVVMDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIVEQDHRFIKKITKPMMGFKAFHSAQATIAGIETAHMIRKGQLSEENIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX8</accession>
    <name>A0A1D3RNX8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmI</name>
        <name evidence="7" type="ORF">BAZMOX_13876_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000682">
        <property type="protein sequence ID" value="SCN47346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_L35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="7404" checksum="3218181A26DD1F4F" modified="2016-11-30" version="1">MPKIKSHSGAAKRFTRTASGHFKCGQSHRSHILTKKSTKRKRQLRKAATIHANDVRMTARMLPYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY5</accession>
    <name>A0A1D3RNY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiol:disulfide interchange protein DsbC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04294_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000755">
        <property type="protein sequence ID" value="SCN47435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03020">
        <property type="entry name" value="DsbA_DsbC_DsbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033954">
        <property type="entry name" value="DiS-bond_Isoase_DsbC/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="1">
        <location>
            <begin position="3"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="100" mass="10717" checksum="42530E55F31415BC" modified="2016-11-30" version="1">MAEGITVQYLFYPRAGKDSESYKKAVSVWCADDRNAALTAAKSNSNPPPVKMCKNPVDKHMALGEALGVRGTPMMVTAKGTIFPGYMPAKRLAAALAQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ0</accession>
    <name>A0A1D3RNZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_202625_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000689">
        <property type="protein sequence ID" value="SCN47364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="202" mass="23029" checksum="F7B69587F894A04D" modified="2016-11-30" version="1">MARLFPIKKINTQDTTTINGIKTYKIGTLINQKLDAAQNRTKVRDLFDINFISDKYGSSFSDKQIEQLGQLARDPDLLLSRYKGDHSADNILKKYSLDDIALKLLLTSDLLHEKYENQKAAKDFKEMSHEEAVKKHPKLAPYVSAVVAIEKRLDADKLTDKEKNIVMQQVQQNAVNNIKQGIITDSKLKTQLVNENNKDLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ1</accession>
    <name>A0A1D3RNZ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_132869_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000721">
        <property type="protein sequence ID" value="SCN47401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4551" checksum="D37AF34107F43C2E" modified="2016-11-30" version="1">MSFFLIIMLVKYVLSDGISQAFLPFRFVDVIVITDHDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP31</accession>
    <name>A0A1D3RP31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_08714_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000645">
        <property type="protein sequence ID" value="SCN47299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="19"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="357" mass="42092" checksum="9912A8973320DBA6" modified="2016-11-30" version="1">MGPEEFTINKNNQTQRIIFLDYLRVFAFLSVLIGHKFYTELSQYISTFSTPHITQKYLSNLFLSMFQGGGAGVVVFFMISGYIILHVLQKEKPFEFIIKRIFRIYPLLIFAIFIQVLLSFLTSHSITDLGVILSQMSLMGDFINTPYALAGVEWTLRVEIFFYILMFLLSFTIFLKNKSYILFSILAILTLSVKFISPFPTENFVGYFTSYFPFLFLGSVLYMYEKKRINLLAFLIFVFIVFYRYFKAMEDYSPHWQNSNFAIVGFSIFIILWLTRNKLQHLPNFINHYITTFALLTYSVYLFHNFLWSYISKFIGYIGMDNKFIVFLILLLWCTLVYKLIETPMNKLGKMISKKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP54</accession>
    <name>A0A1D3RP54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Octaprenyl-diphosphate synthase / Dimethylallyltransferase / Geranyltranstransferase (Farnesyldiphosphate synthase) / Geranylgeranyl pyrophosphate synthetase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_04234_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000632">
        <property type="protein sequence ID" value="SCN47278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="336" mass="36723" checksum="B206A7A2FDEEFB14" modified="2016-11-30" version="1">MTASKNTDNKAPGPIDFASIQSLTESEAQAIDQLILDELSSDVVLINQLGHYIINSGGKRLRPMLLILTAKALNYNENKHLLLAAVIEFIHTATLLHDDVVDESGLRRGKESANAVWGNAASVLVGDYLYSSAFEMMVRTNNMRVMEILSKTTTAIAEGEVLQLLNCNNPATTEAKYLEVISRKTAILFSAATRLGAVISDASPKIEKSLADYGQHLGMAFQLIDDALDYTSSKDELGKNLGDDLAEGKPTLPLIYAIEKGTEEQANIVIEAIKTGSRESFHAVYEIVKATNAINYTELRAEEEAKKAIAAISILPDSKYKNALELLARFSVQRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP56</accession>
    <name>A0A1D3RP56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type I restriction enzyme endonuclease subunit</fullName>
            <shortName evidence="2">R protein</shortName>
            <ecNumber evidence="2">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_23252_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Subunit R is required for both nuclease and ATPase activities, but not for modification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">The type I restriction/modification system is composed of three polypeptides R, M and S.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000754">
        <property type="protein sequence ID" value="SCN47434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004473">
        <property type="entry name" value="Restrct_endonuc_typeI_HsdR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022625">
        <property type="entry name" value="TypeI_RM_Rsu_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12008">
        <property type="entry name" value="EcoR124_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00348">
        <property type="entry name" value="hsdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="68"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="808" mass="92210" checksum="F42A7A89FFC459CB" modified="2016-11-30" version="1">MNWAKSDNTLIKDLKDFTATFFQKNTLLNVLLHYSVFDVSGTLLVMRPYQIAATERILWKINSAYQGKNWSHTESGGYIWHTTGSGKTLTSFKASRLATALDFIDKVFFVVDRKDLDYQTMKEYQRFSPDSVNGSDSTAGLKRNLDKDDNKIIVTTIQKLNNLIKGEGELPVYQSQVVFIFDEAHRSQFGEAQKNLKKKFKKYYQFGFTGTPIFPQNALGAETTSSVFGRELHSYVITDAIRDEKVLKFKVDYNDVRLQFKAIEAEKDELKLTAAENKQAFLHPDRIAEITRYILTHFSQKTHRQQTGGKGFNALFAVSSVDAAKAYYEAFKHLQQGADSNKRLNVATIFSFAANEEQDAIGAIPDESFEVTAMDSSAKAFLSTAIDDYNTAFKTNFGVDSNGFQNYYRDLALRVKKQEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLMQAFSRTNRIYDATKTFGNIVTFRDLEQATVDAITLFGDTNTKNVVLEKSYKEYMEGFTDITTGDARRGYLEVVAELQSRFPNPDDIVLEKDKKDFAKLFGEYLRVENILQNYDEFAGLKALQSIDMDDVQAVEAFKEKFYLNDDDLAAMQNIKLPSERTIQDYRSTYNDTREWLRREKAANDKESANIDWDDVVFEVDLLKSQEINLDYILELIFEHNKKNKSKAHLIEEVRRLIRASLGNRAKEGLIVDFINQTNLDDINDKASIIDAFFSFAQTEQKCEAEELIRSESLNEGAAKRYITASLKREYASENGTELNSTLPKMSPLNPQYKTKKQSVFQKIADFVEKYKGVGGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP70</accession>
    <name>A0A1D3RP70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iso-IS1 ORF2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_315435_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase 27 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000807">
        <property type="protein sequence ID" value="SCN47535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005063">
        <property type="entry name" value="Transposase_27"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03400">
        <property type="entry name" value="DDE_Tnp_IS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="57" mass="6768" checksum="3C75916384490CCC" modified="2016-11-30" version="1">MGKKSNQRWLWHAVDHVTNTVIAYVFGKRKDVIFKELKVLLAPFKINRYYTDDWGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP92</accession>
    <name>A0A1D3RP92_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_09834_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000773">
        <property type="protein sequence ID" value="SCN47466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026349">
        <property type="entry name" value="CHP04255"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04255">
        <property type="entry name" value="sporadTIGR04255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="240" mass="27370" checksum="45F5DBC40059EE53" modified="2016-11-30" version="1">MPEFIPQIHDLLRKEGFPEDFSATVQQVVITPGNKPEITERKQDEFRSKDNQWSLTIGEDMLVLVTTAYDRFEEFANRLKRSLEVIDQIAGIHHGMINRIGLRYVDVIDPPEGKTFKDFLQDSLHGPKSSIFTESNQWLHLESVGRTKLGTMIVRITQNDKGAVLPPDIVMHKPMEQKMQIDAGKVITLVDSDHFVEGAWDYDLDSIMSTTHELHQAINAAWFNDLVTEDALEIWGAKPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF3</accession>
    <name>A0A1D3RPF3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Flagellar hook-associated protein 1</fullName>
            <shortName evidence="7">HAP1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flgK</name>
        <name evidence="10" type="ORF">BAZMOX_05330_4</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Bacterial flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000832">
        <property type="protein sequence ID" value="SCN47573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002371">
        <property type="entry name" value="FlgK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30033">
        <property type="entry name" value="PTHR30033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01005">
        <property type="entry name" value="FLGHOOKAP1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02492">
        <property type="entry name" value="flgK_ends"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="9">
        <location>
            <begin position="492"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="555" mass="58413" checksum="FF51868DBE5FED8A" modified="2016-11-30" version="1">MAFQRSIETTSNNIANANTEGYSRQRVETVASLPEYSGGGYIGTGVQVSNITRSYDQFISAQLRSSTSAFGEVDSFKSYAAQIDNLLADPTTGMDPAMQSFFNSVNDVANDPSSIAAREVMLTEGASLTHRFGMISNRFDELKDQVNSDLKSMTQTANSYAVEIAALNKRIATDIGRANGQQLPNDLLDQRDNFLNKLADLVDVSVIPQANGMVSVLMSNGLPLVMDAQAATLGIKANDFDPTRLDVTYTDAKGQEQMITDRVKGGKIAGALRFRAEILDPAQQKLGAVAAAIAIDFNAIHAAGYDLDGTLGGAFFKFTGTPEVPAIAASANLGTATITAAFSANTADLNTSDYLLELNAGVYTLKRLSDDSSINLTNTAGVLTATSPDVLPGITLTITAGVMVAGDQFFIRPTYQAASNLAMNIEDPRKIAAATNLDADGITLVAGAMPGDNRNALNLAGLANSTGMFNGTASFQESYGQIVAKVGGLTHAANISADAQQSLLNRATEARENLAGVNLDEEAANLIKFQQSYQAAAQAISTASTLFDTLIGAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPI1</accession>
    <name>A0A1D3RPI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidinol dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02140_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.1.1.23" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000854">
        <property type="protein sequence ID" value="SCN47603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="176" mass="18796" checksum="D92138913DEE5276" modified="2016-11-30" version="1">MDLFSQAEHDEDAQAILLSDDADFLDAVAQSIDRLLPEMERAEIIKASLSGRGALIKVASLEEAAQVSNTIAPEHLELSVENPTALCEHINNAGAIFMGRYTAEALGDYCAGPNHVLPTSGTARFSSPLGVYDFQKRSSLIFCSAEGANTLGKTASVLARGESLTAHARSAEYRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM0</accession>
    <name>A0A1D3RPM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_179926_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000925">
        <property type="protein sequence ID" value="SCN47685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009387">
        <property type="entry name" value="HigB-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06296">
        <property type="entry name" value="RelE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039032">
        <property type="entry name" value="HigB-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="113" mass="12756" checksum="4F7B1AC9BD38D775" modified="2016-11-30" version="1">MQTIVELPEYIQRASRLLSEPEKKGIINYLASHPQSGAIMQGTGGIRKFRWASGNKGKSGGVRVIYYYYNKLIPLFLLTVFGKNEKDNLSKSERNELAKFANLLSKNYGEPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN0</accession>
    <name>A0A1D3RPN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_72545_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000718">
        <property type="protein sequence ID" value="SCN47397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="105" mass="12087" checksum="75D1E92665C0C492" modified="2016-11-30" version="1">METIDNHNIYADADIERAARCLKAMSHPLRLKILCVLGTEAISVQDIVEKVGTSQSNISQHLSILREKDILGFKKDANRVFYYIDDPRMLKLIEMMREIFCAECK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN5</accession>
    <name>A0A1D3RPN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">UDP-2,3-diacylglucosamine hydrolase</fullName>
            <ecNumber evidence="10">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_00950_3</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.6.1.-" evidence="10"/>
    <dbReference type="EMBL" id="FMJP01000793">
        <property type="protein sequence ID" value="SCN47499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00575">
        <property type="entry name" value="LpxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010138">
        <property type="entry name" value="UDP-diacylglucosamine_Hdrlase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990:SF1">
        <property type="entry name" value="PTHR34990:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01854">
        <property type="entry name" value="lipid_A_lpxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="9">
        <location>
            <begin position="6"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="241" mass="28073" checksum="D17A5ECF89BD4902" modified="2016-11-30" version="1">MPNETLFISDLHLTIERPEITQKVLKLLTGRAKQAKALYILGDLFDTWIGDDDFSPPIKTVKKHLKALTEQGTPIFYIHGNRDFLIGQRFSKESGITLLDEYSVIDLYGTPTLLTHGDLLCTDDLPYQAFRVKSHSEEWQKNVLSKPLILRILYARWYRLRSFFHKRKKSQDIMDVNQDTIVSVMHKYKTTRLIHGHTHRPAVHDLKINNLRGQRFVLAEWKKESASILVWTASGYTQERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN6</accession>
    <name>A0A1D3RPN6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0246 protein BAZMOX_168091_0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_168091_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0246 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000862">
        <property type="protein sequence ID" value="SCN47606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00652">
        <property type="entry name" value="UPF0246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005583">
        <property type="entry name" value="YaaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30283">
        <property type="entry name" value="PTHR30283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03883">
        <property type="entry name" value="H2O2_YaaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="255" mass="29197" checksum="0823DC4D66D8FBD1" modified="2016-11-30" version="1">MLMLISPAKSLDMQASVPKITPTKPRFLDDSQQLINQLQELNPEQIQQLMGISEKLSELNYQRFQAWVQSDATAQCPALFAFQGDVYQGLGANLLTMDELEFAQRHLRILSGLYGLLRPLDLMQAYRLEMGTKFVNKRGANLYTFWGDKISALIKADMPPDEAPELVNLASNEYFKAVKPKLIENKVINPVFKDFKNGQYKIISFYAKKARGLMVAYALRNKITQAEQLKEFDSAGYHFAEELSDDKQWLFIRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP3</accession>
    <name>A0A1D3RPP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_09834_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000773">
        <property type="protein sequence ID" value="SCN47468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="289" mass="33388" checksum="069F7F7AFC20D12F" modified="2016-11-30" version="1">MVDKVTPDTAEQIRAHDCKQGRLISPENTAKIIEDAIDFYDKDGSTDTWLVVITQDCDLVRRIHDEPYVELLALQELSSKPGFPMRGHSARKLHLANNNTWFECNIHDRFRIKKESLLKTDCNSALAFSENEQRLLRQWLARRYARAAFPDHFENHLQSTKSGPVKKLFKSAAAKLISTVYIDIDHEDAGGNEDYYIHVILTALAEDLADPEKRDQIDDFEERFIRVFDNRPHICLALKDPDDQESYDVRVISEEDVTLSMLRRYKRFDADYRSVDDDTLSPPDGIDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ4</accession>
    <name>A0A1D3RPQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Na(+)-translocating NADH-quinone reductase subunit E</fullName>
            <ecNumber evidence="10">1.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_106578_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.6.5.-" evidence="10"/>
    <dbReference type="EMBL" id="FMJP01000913">
        <property type="protein sequence ID" value="SCN47671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009276">
        <property type="term" value="C:Gram-negative-bacterium-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010967">
        <property type="entry name" value="NqrE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30335:SF1">
        <property type="entry name" value="PTHR30335:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="70" mass="7485" checksum="8DB72D516AA07F03" modified="2016-11-30" version="1">MIERDYDFTQSVVYGAGSGFGWALAITVMAGVREKLKYSDIPKGIEGLGITFISAGLMSLGFMAFSGIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS9</accession>
    <name>A0A1D3RPS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PIN_12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_160466_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000909">
        <property type="protein sequence ID" value="SCN47664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032557">
        <property type="entry name" value="DUF4935"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16289">
        <property type="entry name" value="PIN_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_12" evidence="1">
        <location>
            <begin position="9"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="69" mass="7863" checksum="A41BDC5F82036580" modified="2016-11-30" version="1">MSLHNYNAILIDTSIFDGNGLRLETGLLGKLRQFKKTKIDLLLPDVIKNEIQSHLEKKLGFQATLLKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT9</accession>
    <name>A0A1D3RPT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">[NiFe] hydrogenase nickel incorporation-associated protein HypB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_23642_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000914">
        <property type="protein sequence ID" value="SCN47674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05390">
        <property type="entry name" value="HypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004392">
        <property type="entry name" value="Hyd_mat_HypB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30134">
        <property type="entry name" value="PTHR30134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00073">
        <property type="entry name" value="hypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="3">
        <location>
            <begin position="103"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="295" mass="32742" checksum="515490201FE1A48D" modified="2016-11-30" version="1">MCVTCGCSDNAKATVTNLDSGKVVTIPADDHEHSHEHDHAHEHPHSHDHEHDHSHNHDHDHSSAHTHAGMHGTTISLEAKILAKNDLLAERNRGWFAGRNILALNLVSSPGSGKTTLLERTIRDLKDSLPINVIEGDQETVNDAERIKSTGCRVVQINTGSGCHLEADMLARGIKELQPPMNSVVMIENVGNLVCPALFDLGEKCKVAILSVTEGEDKPLKYPHMFRAAEVMLLNKIDLLPYLNFKVNDCINYAKRVNPDIKIFQLSATTGEGMGNWYDWLQQQLQQKNKNQDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU3</accession>
    <name>A0A1D3RPU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_55186_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000910">
        <property type="protein sequence ID" value="SCN47666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014795">
        <property type="entry name" value="Vibrio_phage_ICP1_Orf50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08681">
        <property type="entry name" value="DUF1778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="102" mass="11537" checksum="B91D3DC277F0757F" modified="2016-11-30" version="1">MTLGRGNTMNSISTQNQRLDMRIDLETKQMAERASAVLGCSSLTEYITRLIRDNSPNIIQQKTQITLSNQQFDQFIALCEDKAIKPSKSLLQAVQQLDKEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV2</accession>
    <name>A0A1D3RPV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_179926_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000925">
        <property type="protein sequence ID" value="SCN47684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="36"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="10633" checksum="20A1673A2905D6CA" modified="2016-11-30" version="1">MSDFFNSIKQGLTEAVEYSEKKCPKAIVHKFSAIDVKATRSNLKMSQTEFASAFGISVSTLRHWERGDRKPQGPALVLLNVVAKEPQAVLRVLSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV9</accession>
    <name>A0A1D3RPV9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FIG004453: protein YceG like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_246502_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000994">
        <property type="protein sequence ID" value="SCN47785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5315" checksum="963BA41D730D4782" modified="2016-11-30" version="1">MPGIASIDAAAHPAKTKYLYFVSKGNGKSHFSNNLKAHNRAVKKYILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW2</accession>
    <name>A0A1D3RPW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase, M23/M37 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_06203_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000808">
        <property type="protein sequence ID" value="SCN47538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040487">
        <property type="entry name" value="Peptidase_M23_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18421">
        <property type="entry name" value="Peptidase_M23_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920284" evidence="1">
        <location>
            <begin position="19"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23_N" evidence="3">
        <location>
            <begin position="26"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="171"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="279" mass="30415" checksum="463934C41B781B54" modified="2016-11-30" version="1">MNKALLACLLVIPQLAFSSPLPKQLAVPGGIVNIELGPITSPAPQVLFQKKRVLVLENDHKWVAVVGIPLNTKVGQYSVTIQSGKQKMQSNFEVNAKDYPAQYITLKNKRMVNPNPDDLKRISSECPAINKALNTWTEQPVDDLSFSLPVQGRLSSPFGLKRFFNNQPKNPHSGLDIAASTGTAITAPAPGVVINTGNYYYNGNTVFLDHGQGLITGYFHMSKITVQAGQLVETGTKLGEIGSTGRVTGPHLHWNVYLNKTKVDPALFVPELMQTDTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX9</accession>
    <name>A0A1D3RPX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_05068_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000978">
        <property type="protein sequence ID" value="SCN47763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5512" checksum="2D2D6852D3BC0006" modified="2016-11-30" version="1">MTQSFQAKNFELAHELKNRIRILVPILEKDPDRTYIFEIILKNVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY9</accession>
    <name>A0A1D3RPY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase IS2020, hypothetical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_444105_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000977">
        <property type="protein sequence ID" value="SCN47761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="7013" checksum="CB00DE5813B92830" modified="2016-11-30" version="1">MNNIIEQDPRFIKKITKPMMGFKAFHSAQTTIAGIETAHMIRKGKLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ0</accession>
    <name>A0A1D3RPZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00676_8</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033014">
        <property type="term" value="P:tetrapyrrole biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="4684" checksum="FCA51C28C8623BDF" modified="2016-11-30" version="1">MLVISRRVYAAAKDIGFTKVVIANEATDAAMINALNNGENCGGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ54</accession>
    <name>A0A1D3RQ54_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpC</name>
        <name evidence="10" type="ORF">BAZMOX_165327_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000920">
        <property type="protein sequence ID" value="SCN47679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="8"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="266" mass="29507" checksum="23555719008F8D6D" modified="2016-11-30" version="1">MTDTPDILKKILAKKTEEVEKRKQRMSIEDLQGIIGDSEKPRGFARALQDKAASKKPAIIAEIKKASPSKGVIRENFKPNEIAQDYAMSGASCLSVLTDKEFFQGSEVNLQMARQSSPLPALRKDFMIDPYQMYESRALGADCILLIVAALSDTQMHELADIAEQLNMDVLVEVHDAAEMERALTLDTPLIGINNRNLRTFATSLQTTLDLKPIVPSDRLVITESGIHTPADVQLMLDNDIYTFLVGEAFMAAEHPGAKMRELFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ63</accession>
    <name>A0A1D3RQ63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid stabilization system</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_30228_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001023">
        <property type="protein sequence ID" value="SCN47831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="11215" checksum="17D91C2D5CE512C6" modified="2016-11-30" version="1">MKIVWTKPARQDLREIFAYIAEEKPRAARALLAEIKERVTVLQNNPQLGRKGHVEGTRELVLSGTHYLLPYRIKNQQVQILAVFHTSREWPNKLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ82</accession>
    <name>A0A1D3RQ82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_01376_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001010">
        <property type="protein sequence ID" value="SCN47806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4362" checksum="087D1069C8EFAC99" modified="2016-11-30" version="1">MLTYALIYQRRLGGKQGLMSDFMIDIQPKNTSKSSKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ83</accession>
    <name>A0A1D3RQ83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tryptophan synthase</fullName>
            <ecNumber evidence="3">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_01607_4</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01001034">
        <property type="protein sequence ID" value="SCN47851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="161" mass="17095" checksum="4C083A1D4785D52D" modified="2016-11-30" version="1">MGYVAFADATQKAGVDGLLTVDLPPEESQECADLLNARNIDQIFLLAPNSNSERIRKMDKVGSGFLYYVSVKGVTGAGHLDTNDVKTKLVDIRANTELPVAIGFGVKDAKTAQTIAGLGDAVVVGSALISKIEANLDSPEQAKQEITELLKSMRTAMDNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ87</accession>
    <name>A0A1D3RQ87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_455398_0</name>
        <name evidence="3" type="ORF">BAZMOX_86047_1</name>
        <name evidence="2" type="ORF">BAZMOX_86659_0</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000238">
        <property type="protein sequence ID" value="SCN46720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01001044">
        <property type="protein sequence ID" value="SCN47863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01001056">
        <property type="protein sequence ID" value="SCN47878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4715" checksum="521F3161D92D4052" modified="2016-11-30" version="1">MGFKAFHSAQATIAGIETAHMIRKGQLSEEYIPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ95</accession>
    <name>A0A1D3RQ95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_31641_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001048">
        <property type="protein sequence ID" value="SCN47870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5939" checksum="94142E9ECB46E12C" modified="2016-11-30" version="1">MLCTDIYFGKYVFKLKWNKIVDDFNPMKGNLLGLGMVLLFFSPAIVFSFQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA2</accession>
    <name>A0A1D3RQA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_30428_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001017">
        <property type="protein sequence ID" value="SCN47826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="26"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="204" mass="21931" checksum="FEFA1DF333746833" modified="2016-11-30" version="1">MKILMVLTSHDQLGDTSQKTGFWLDEFASPYYVFKDALADITLASPLGGQSPIDPKSEAADFQTEATQRFNKDTAGLKLLANTLKLSDIVAEDYDALFYPGGHGPLWDLVDDADSIALIETMYASRKAVAAVCHAPSVLLKAKAVNGSSLVKGKSVTGFSNSEEEAVQLTDVVPFLLENELIAKGANYSNLNSYNKCITSESNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA3</accession>
    <name>A0A1D3RQA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_306521_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001059">
        <property type="protein sequence ID" value="SCN47880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="198" mass="21887" checksum="9DCDD3A77BA351B8" modified="2016-11-30" version="1">MTRLLSTYTKQSTMLKNKIHGEAVLGNPSKLVTSSLKCSLRNVKKQIEKVESALLILVKEVHQDVLTRLKTIPGIGDKTAIMLVVLTDGFDRFKSGSELCSYAGLTPVIRQSGSSVKGRPRISKIGNQKLRNLLFMCSFNACKYNKACKAIYDRIVAKGKSKKLALMAVCNKLLKQAFAIAKSGLIYDDTYRSVLVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA6</accession>
    <name>A0A1D3RQA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_45097_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000948">
        <property type="protein sequence ID" value="SCN47729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4250" checksum="47F6D3EC8AB3AA3E" modified="2016-11-30" version="1">MVQPDNHVSFESIDLSLSVAQIYHRVQNDDMIAFNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD1</accession>
    <name>A0A1D3RQD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_15702_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01001083">
        <property type="protein sequence ID" value="SCN47910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006486">
        <property type="term" value="P:protein glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="PTHR11214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="307" mass="36670" checksum="88F3849BD9F0C276" modified="2016-11-30" version="1">MKYKKNARKRDVLCIITFSVILFVHIFYHEKCTRRLQQYEIRFHQIVEEHQNRQLQQKQLFKEKSRTSKITAEIQITSQTEYNITHNRKVEQLPHLVLGILSLTEDPVRRTAVRATWISTLIRLKHQIPFRITYKFLLDKPTNDSLNENNVYKDILYLNVTHHGYAYKYGEKVYKWYKYVHENYPDAVLGARIDDDVFLCVPQMLNRLNELKSPILYYGWKHGKGNKPHRDCSIDEMFVVLGRDLIKRIADRHYCGSFTCTNDGDLVERNYGSTSLSVWLSIYKDVYIHADNNRMIFLAEERLREIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD6</accession>
    <name>A0A1D3RQD6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RHH_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_30228_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001023">
        <property type="protein sequence ID" value="SCN47832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="9678" checksum="F17A5BE0EED5CAE9" modified="2016-11-30" version="1">MSTEAFTVRAEENIVHQLDHIAGSLDRSRNYLVNQAIQEYLETHAWQIEKITQGVEAADNGELVEHDQVMQEMDALIEQKAINKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD7</accession>
    <name>A0A1D3RQD7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Intracellular septation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_07964_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000929">
        <property type="protein sequence ID" value="SCN47698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00189">
        <property type="entry name" value="YciB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006008">
        <property type="entry name" value="YciB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36917">
        <property type="entry name" value="PTHR36917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04279">
        <property type="entry name" value="IspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00997">
        <property type="entry name" value="ispZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="182" mass="21104" checksum="F080F14B710025DA" modified="2016-11-30" version="1">MNKILFDFFPIVLFFIAYKNYDLYVATAVVIGATFVQVAYSWFKLRKVETMQWVTLGLMVVMGGATLYLQDEQFIKWKLTIIEWLFGAVLLGSQFIGKKTIMEKMMGANLELPKKVWSILNTVWALFFISIGVINIYVMFNYDTETWVDFKTFGVPALMAVFILLQLAFLYKYMPEPADSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQF7</accession>
    <name>A0A1D3RQF7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-binding protein BAZMOX_06712_2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_06712_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000943">
        <property type="protein sequence ID" value="SCN47718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00636">
        <property type="entry name" value="RapZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="60"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="285" mass="32461" checksum="E7AF541770579440" modified="2016-11-30" version="1">MKLLILTGLSGSGKSIALDALEDCGFYCIDNLPITLLDDFVTNVMKQDPKTYNKTAIGIDARNHSESLYAFAEKLALIRAQGIYCDVIYMQAEAEVLLKRYSETRRRHPLTDLNLPLKEAIKIEKEMLKSVAKCADLVVDTSRTHYHQLRELIRGYVQEGSQQKISIQMQSFGFKHGLPLDADFVFDARCLPNPYWNPKLRGFTGKDQPVIDFLNSESIVTEFFQDISGLLERWIPRFEKENRSYLTVAVGCTGGQHRSVFLVDSLARYFQSKGSNVIIRHRELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQN9</accession>
    <name>A0A1D3RQN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplK</name>
        <name evidence="11" type="ORF">BAZMOX_30461_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6 8">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6 8">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001018">
        <property type="protein sequence ID" value="SCN47828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="9">
        <location>
            <begin position="72"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="143" mass="14867" checksum="DD5BA8797EF880C9" modified="2016-11-30" version="1">MAKEVSAYIKLQVKAGEANPSPPVGPALGQHGVNIMEFCKAFNAKTADIEKGLPIPVVISVYSDKSFTFITKTPPASILLKKAAGITSGSAVPNKTKVGTVTLAQVEDIAKTKMEDLNATNLETAVKIIAGSARSMGLVVEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQR1</accession>
    <name>A0A1D3RQR1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PABS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_79250_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001046">
        <property type="protein sequence ID" value="SCN47868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="4">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="7428" checksum="2414FBEA43367240" modified="2016-11-30" version="1">MVKIARRFFSLPLEPRLKIKIADGAHYIKQQSLQSPRQHDFILLDAFDHAGMADTVQGINVFFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQU0</accession>
    <name>A0A1D3RQU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02007_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001073">
        <property type="protein sequence ID" value="SCN47898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="78" mass="8385" checksum="4076ADCCBE525DEA" modified="2016-11-30" version="1">MLIILIAIITAIVFFNSGKKNGENGENGIKWSVTGLIGYILGFAIGMGAIGETFISIFIGCISVYLTHLQLVKMAHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL43</accession>
    <name>A0A1D3RL43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_290458_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000004">
        <property type="protein sequence ID" value="SCN46393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4977" checksum="B78A930978BB6E54" modified="2016-11-30" version="1">MTHVLQVLFLSVFILQVVMHGEESQVPGDLRHSEILIEQDFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLB3</accession>
    <name>A0A1D3RLB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV fimbrial assembly, ATPase PilB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_01179_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000036">
        <property type="protein sequence ID" value="SCN46434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SSE_N" evidence="3">
        <location>
            <begin position="8"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="100"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="239" mass="27200" checksum="E7BF2C5246788602" modified="2016-11-30" version="1">MLYRYLKRGNRLFIALSDPTNFQALDDIKFHTRLNTETILVEEDKLVAAIDSFLEAADTSMTDLLDTDLDNIELSGGDEEAKDEVNSDIDDAPIVRFVNKILLDAIKKGASDIHLEPYEKTFRIRFRSDGMLSEVASPPSNIANRIISRIKVMSKMDIAERRVPQDGRIKMTLSRNKAIDFRVNTCPTLFGEKVVLRILDPTSAQLGIEKLGFEPVQQKLFLDAIQKTLWHDSSNRPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLD9</accession>
    <name>A0A1D3RLD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00432_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000065">
        <property type="protein sequence ID" value="SCN46476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="15989" checksum="04A9A428A50D41A9" modified="2016-11-30" version="1">MEELNSENIAKKMEALKANMNKKIEEKKKPKTSKKILFLREIGSVIKEKYDDGISYKDMSKSIEEIFSIKVNEQTIRAFAHAELGIPKKVKKNSPSSAEPVKNEVLKEEAAESIPVAEAPKKMSVKEQRRANAEKAKEENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLE6</accession>
    <name>A0A1D3RLE6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YcxB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_11721_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000081">
        <property type="protein sequence ID" value="SCN46501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025588">
        <property type="entry name" value="YcxB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14317">
        <property type="entry name" value="YcxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="YcxB" evidence="2">
        <location>
            <begin position="106"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="173" mass="20384" checksum="2217222458EF6500" modified="2016-11-30" version="1">MLEIEYEFREKDLIHYNELQIESSEDLQKKLKRNRLFFPGVLSIFGLFLWSYYSDYRTALYIITISICWAIVIPQIIILSFRKQILDNYTDREKQAMFGKYTLRIDPKALAENSPSGKNKMPWKTILRIEHIRDYIHIVLDNGAALVIPIETVSAGDIKEFSKQVKKMIELYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLG2</accession>
    <name>A0A1D3RLG2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maturase integron/retron-type RNA-directed DNA polymerase (Reverse transcriptase) part of type II intron</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04471_7</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000015">
        <property type="protein sequence ID" value="SCN46409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="214" mass="25546" checksum="184E200F36E229A7" modified="2016-11-30" version="1">MLNDLDRHLESKDYRFARYADDFVISVKSLVEGERIKAEVVVFLDTLKLPINEEKSQVVPIKQLSFLGFIFKGKKIIWSPKSLANFKHRIRELTGRSWGISWAYRHQQLRRYIVGWINYFGLSEYYRPVPLLDQWIRRRVRMCYLKQWRKPRTRIRNLIRLGVSKMTAIRLGLSSKGYYRLAKTKAVQMGLNNDWLTSQGLISVQQQWSKFHYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL0</accession>
    <name>A0A1D3RLL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_452316_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000056">
        <property type="protein sequence ID" value="SCN46459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="3"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="67" mass="8238" checksum="3E8268DA8CE203E9" modified="2016-11-30" version="1">MDGRGRALDNIFVERLWRTVKYENIYMNDYQTVPELRSGLKRYFEFYNQERLHQSLDYQTPSDVHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL3</accession>
    <name>A0A1D3RLL3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_03205_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the system for phosphate transport across the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000127">
        <property type="protein sequence ID" value="SCN46552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5027158791" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="28"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="42"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="327" mass="34937" checksum="D454045044273B97" modified="2016-11-30" version="1">MKITSKVRSLAAAGFVTAVLVSTSANAVQTVDPKLPDYQKASGVSGNLSSVGSDTLANLMTLWAESFKRNYPNVNIQIQAAGSSTAPPALTEATANIGPMSRKMKDKELDAFERKYGYKPTAIPVAIDALAVYVNKDNPIEGMTIPQVDAVMSSTRKCGYPTDITTWGDLGLTGSWKNKSIQLYGRNSVSGTYGYFKKKALCKGDFKNNVNEQPGSASVVQSVSTSLNGIGYSGIGYKTSGVKAVALTKKAGGAFIAATPENALSGKYPLARFLYVYVNKKPNQALAPLEREFIRMVLSKEGQKIVIKDGYIPLPAKVVKKSLAELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM0</accession>
    <name>A0A1D3RLM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Competence protein F homolog, phosphoribosyltransferase domain protein YhgH required for utilization of DNA as sole source of carbon and energy</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_08412_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000063">
        <property type="protein sequence ID" value="SCN46469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044005">
        <property type="entry name" value="DZR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18912">
        <property type="entry name" value="DZR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DZR_2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="237" mass="26890" checksum="9F06E40D791654DD" modified="2016-11-30" version="1">MVNNWFDIIQYSLLSTSCILCNKPGMERIDLCAACYHALEKMEDQCYCCAKPFAIHSSTPRLCGKCQKNPPAFNKTYSPFIHQGAIRYLINQLKFKGAYKNSRLLGLLLANYLEKNAELPGLIIPVPLHSNRYKQRGFNQTHEIAKTIAKELDLAIDISCCQRIKNTPHQISLTAKQRRKNIKNAFQVTKLPKVNHIAILDDVMTTGATANELARRLKIAGVNRVDVWLCARAKMDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM5</accession>
    <name>A0A1D3RLM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytoene synthase</fullName>
            <ecNumber evidence="1">2.5.1.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_81665_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.5.1.32" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000136">
        <property type="protein sequence ID" value="SCN46566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016767">
        <property type="term" value="F:geranylgeranyl-diphosphate geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="PTHR11626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="359" mass="40159" checksum="C80F051E06F55A61" modified="2016-11-30" version="1">MTDTNLSIDDPESLLAASVDEFQAILLEGVSRTFALTIPQLPRGLYEAVANAYLLCRIVDTVEDEVSLTAEQKEQFLSRFIEVVKTGKDAQAFATDLAPLLSEQTIPAEHILIKVTPRVIDITHSFAPKQIEALLSCVETMAKGMPAYQNMDLQGGLATLKDMDEYCYYVAGCVGEMLAKLFCHYSPEINKHHDQLLKLSTSFGQGLQMTNILKDIWDDAQRGVCWLPQDIFTETGFDLKDLNTATSTKEFQLGLEHLISIAQGHLKNALTYTLLIPSHETGMRNFCLWALGMAVLTLNEIKAHLDFNDSDQVKITRKSVKRTILTTKLIGRSNFLLTYVFNAKSKALICTDWHYQAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN8</accession>
    <name>A0A1D3RLN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_518265_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000151">
        <property type="protein sequence ID" value="SCN46580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="66" mass="7254" checksum="79B3218B045910FA" modified="2016-11-30" version="1">MGLGKIRTNQFLANAALFHCAVLAYNTVRWMAQATIAGIETAHMIRKGQLSEENMPAYKQFIALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR3</accession>
    <name>A0A1D3RLR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04471_5</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000015">
        <property type="protein sequence ID" value="SCN46407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014056">
        <property type="entry name" value="Addiction_killer_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41791">
        <property type="entry name" value="PTHR41791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028744">
        <property type="entry name" value="Addict_mod_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02683">
        <property type="entry name" value="upstrm_HI1419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="86" mass="9596" checksum="464CA486214EFAF5" modified="2016-11-30" version="1">MKKLKDRQAVKTIAIRMDRAILGNLGDIKPVGQGVSEMRIFVGKGYRVYFVIRNNKVVFLLCGGDKSSQEADIKQAKELAILVEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLR5</accession>
    <name>A0A1D3RLR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_32210_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000178">
        <property type="protein sequence ID" value="SCN46621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="64" mass="7693" checksum="1A3371B2456AC3D6" modified="2016-11-30" version="1">MQCELCKFSIPHSGRFFVEHCRYYSTLEKKQLMLLAAEIDQCSFFELDSKEGPHFEREIPYEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS1</accession>
    <name>A0A1D3RLS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_423585_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000172">
        <property type="protein sequence ID" value="SCN46612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4946" checksum="19335ED7BAC2F600" modified="2016-11-30" version="1">MALLRGLAIELIRKTSPKNFQAAIEDLSDSIANLESMLRQVKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS4</accession>
    <name>A0A1D3RLS4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ORF">BAZMOX_47618_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000174">
        <property type="protein sequence ID" value="SCN46616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="309" mass="33337" checksum="341EC2325E8607C1" modified="2016-11-30" version="1">MLKEIDFLGKRKFAAIFSSLLLLVTIGSLAVQGLKLGIDFTGGTLVEIGYKKAVNLKVMRAGLEAAGINDATVQHFGSSQEVLIRLKPQEGVSNAEISTNVLNAVNVGMAEKGDVRRVEFVGPQVGDELTEDGGLALLYSMFGILIYVAWRFEYKFALGSVAALAHDVLITLGCFSVFQMEFDLTVLAAILAVIGYSLNDTIVVYDRIRENFRLLRKGSSEVIMNASLNQTLSRTLITSLTTLLVLVALAILGGEIIHNFAIALLIGVVVGTYSSIYVASPLVLALGVSKEDLMVPEVEVEGKEFDMMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS8</accession>
    <name>A0A1D3RLS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_32210_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000178">
        <property type="protein sequence ID" value="SCN46620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5051" checksum="AB5BBF5367ACC9B3" modified="2016-11-30" version="1">MLWLKETHQVPSWDIESGESINYALVEEFARSSGFQKKGCDYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT3</accession>
    <name>A0A1D3RLT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_57212_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000028">
        <property type="protein sequence ID" value="SCN46427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="166"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="522" mass="59833" checksum="C68493E2E611DC83" modified="2016-11-30" version="1">MFYISFFPKPYYIISILLRVLALLIFVLYSVDYLVIANFNTHLVFNDAIKYSSYSFKYISQISNKKIIAAIIAIIIMTGFMLLIVFLRGRIRSKIFHITYIFLIINLLLTSRLKQNDSYVHSWIYKDFISYNLTILSESKLYSADFVENFEFSDELHCSSKIAYKKNFIILMVESLSSYQSAFFSGIKDWTPQIDTIAANNIAFKDFYANGFTTEDGEVALLLGKIPIRAPATYSDGGGSSFTGFYYDVTRTLPNILKSKGYVSEFLTTADLMFSNTDIFAKNIGFDYIEGHEHPYYDNWDRSHFKAAPDEALYHRALSRIEKNKGNNFFVFIKTVSTHVPYINPETKHSSEAETFLYADKQIGLFYKELLNIGFFNNGILIIVGDHRAMIPLKEKEIEQFGALKAAAIVPLIISYGDAIRSIEDKPYQQIDVFNGIKNLVSNTECSSDWVGDVLAYDKKSPKYIAHRRGDNRDIISVFSTKNSYLIKLDGDKTRITSDNNLDKIISDNLVNKINFSRIHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT9</accession>
    <name>A0A1D3RLT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Possible ATLS1-like light-inducible protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_11390_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000203">
        <property type="protein sequence ID" value="SCN46665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="PTHR11954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="115" mass="12654" checksum="CCC7EC4D5602759D" modified="2016-11-30" version="1">MPFMKLRTNLVIDSAKASSLMSEMSKLLANETAKPERYVMIDVKGDRNMMFGGSSEPLAYIECKSIGLSTAQAKSLSKSISELLGAQLQLGAERIYIEFSNCPAEYWGWNGSTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV5</accession>
    <name>A0A1D3RLV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Secreted trypsin-like serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_19324_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000188">
        <property type="protein sequence ID" value="SCN46643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="6"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="357" mass="39450" checksum="22EB43C121643ADC" modified="2016-11-30" version="1">MKSPKIIGGATSSSNAWPWMVAIYHSQGIRGKKFQCGASLIDKDWVLTAAHCVKGKSAANLSVVINRSDQTDKKMGENIKIDEIVIHAKYRGEAHDNDYAIPPDNDYAMLKLTSSSSIKPIQLVSPYALPEWTERDAKALGWGNVIPTTKYDSDPDNEDSLYPKKLREVDLTIIRDSLCSKSERMSNLYGKDWITDNMICTGDGLGTKDACDGDSGGPLIVFDSSTNAWLQAGVTSFGDGCAETGTYGVSARIPEITRWVSELMCSNEEVPDIPSSLEFDIHDDNSVTVTWDRVSGATGYHLNYRWPDYPTYNSIDLNSNTFTSDPIDSGAEFYITITSLKNNCLSKETKEKYVIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW7</accession>
    <name>A0A1D3RLW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prs</name>
        <name evidence="8" type="ORF">BAZMOX_09208_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000141">
        <property type="protein sequence ID" value="SCN46569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="21"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="241"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="54"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="113"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="332" mass="35885" checksum="E8F4BE2B3265A0B6" modified="2016-11-30" version="1">MSNASMSNASMSNASISDASMMVFSGNANLVLSKDIARRLSMRLGMATVGRFSDGEVMVEIEENVRDKDVFIIQPTCAPTNENLMELLVIIDALKRASASRITAVMPYYGYARQDRRSRSARVAISAKLVAKMVGVSGADRVLTVDLHADQIQGFFDIPVDNVYASPLLLGDVWRQNYKDLIVVSPDVGGVVRARALAKRLDDADLAIIDKRRPRANVAEVMHIIGDVSGKTCVMIDDLVDTAGTLCSAASALKKQGAVRVVAYCTHPVLSGRAIENLRGSELDELVVTDTIPLNKEAEALGKIRQLSVADMLAETIRRIAVGESVSSLYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY0</accession>
    <name>A0A1D3RLY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_02677_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000206">
        <property type="protein sequence ID" value="SCN46670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002094">
        <property type="entry name" value="OMP26_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920221" evidence="3">
        <location>
            <begin position="21"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="165" mass="18650" checksum="5C8B2DD205A2722E" modified="2016-11-30" version="1">MLKKMFFLAALMMASQAVQAEIKIGVVNVPLLMANAPQAADAKKRLEKEFSPKDKQLVSQAKAIKKLEEKLARDGLTMTDTEKRKLERDIIAKRRDVQRAQQEFKEDFSIRRNEELGKMQTRIIEAVKALAAEGKYDLLLTEGVIYASPKVDVTSKVQEKLSTMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY4</accession>
    <name>A0A1D3RLY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11390_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000203">
        <property type="protein sequence ID" value="SCN46664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="50" mass="5648" checksum="9933C98B77E03BFF" modified="2016-11-30" version="1">MNKISDEERKKILESPPIGTWVLMLSVGGGMVVAWLFLYYGVFLSRGMIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLY8</accession>
    <name>A0A1D3RLY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_49042_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000207">
        <property type="protein sequence ID" value="SCN46673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="97" mass="10631" checksum="0168FF6FB5C9C568" modified="2016-11-30" version="1">MIHTALILGINFTKPKVDKTSKSIEITLVTNKAKKAPEKAEFLAQSNQMGAGKKRDKPTPAAQKLASSGTHSKQPPRQKVLKQQSIKRQKILNSKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM02</accession>
    <name>A0A1D3RM02_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_13546_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000077">
        <property type="protein sequence ID" value="SCN46497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02385">
        <property type="entry name" value="RelE_StbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="10281" checksum="C8C531A2E2A3DE0B" modified="2016-11-30" version="1">MSWELRYTKQAQKDAKKLSSSGLKAKAELILHIVKENPYQNPPPYEKLVGDLNGAYSRRINIQHRLVYQVYKNEHIIKVLSLWTHYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM11</accession>
    <name>A0A1D3RM11_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_Tnp_IS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01011_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000111">
        <property type="protein sequence ID" value="SCN46538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024431">
        <property type="entry name" value="InsA_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12759">
        <property type="entry name" value="HTH_Tnp_IS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_Tnp_IS1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="116" mass="13359" checksum="34A189BD81A60634" modified="2016-11-30" version="1">MLDYRYNACAPGIKEKVVEMAINSSGIRETARVLKIDKNTVISILKRKEDSLVQVNPIFLSENTESPKVRDLYDLNYLSENYSHSFSEQQKEQLAEFAKNPDSLVSRYSQNHSEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM23</accession>
    <name>A0A1D3RM23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General secretion pathway protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_00699_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000100">
        <property type="protein sequence ID" value="SCN46517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="70"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="274"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="405" mass="44399" checksum="13127D82DD511647" modified="2016-11-30" version="1">MTLFVYKAVAHDGTVQEGTKEAKDEAHLIDYLQSEGLIPLKISLSGSSLSHLFSFKRSQEGLSQKEVNLFTKELATLLQAGLPLDRSLVVLMELIDPDSKIHDLIKKVLERVKGGVNLADALEAESSAFSRFYINMLRAGEAGGSVDIVLGQLSEYLEKSKELKDTVSTALIYPTVLVVMALGSVFLLLTFVVPQFTEMFESAGKELPISTQIVVGTAEWLQSYWWILLIGGFATFFIMRYELTVGPRKAQWDGIILSLPLFGEIIRNTSTTNFTRTLGTLLSNGVPILTALGIVKGTLSNLVLIDALTLAEDNLKQGKDMSSALIESGQFPKMATQMIKMGEETGKMEEMLARTAETYDKQLKITIERMLAMLEPILIVTLGLLIAGIIISILSAILSVNDLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM34</accession>
    <name>A0A1D3RM34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensory transduction histidine kinases</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_114940_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000105">
        <property type="protein sequence ID" value="SCN46527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="129" mass="14379" checksum="9A5B45EBDAE106BE" modified="2016-11-30" version="1">MKIDYVMPECRVLADKEQLVAILGHLVQNSQDATPDDGEVRIRLDCDQDNVLIDVIDTGCGMEQKFIAERLFRPFDTTKGNAGMGIGVYEAREYILSQDGDISVLSEVGVGTVFSIKLPRVIQQDQEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM77</accession>
    <name>A0A1D3RM77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA circulation protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_67306_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000256">
        <property type="protein sequence ID" value="SCN46746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="318" mass="36579" checksum="1E5EE6BF377DDBC1" modified="2016-11-30" version="1">MEWSNTFEYLPSSETQIGYFLGSDRQRSTGQFYTQVSHRGRSAYLRTIEIAKKFYDMPDTYAEHLSILALPIEPAYTGFKPRKPFWLPRWDRNSTADIEGITKFVKIALENFGLIDNSQELLTFSIPIKIDEHNWIDLSIVRAAIFKNSGKALQIEERSGCITVGALIDPELTYEFSNDDENHSGVMATTPYPLNRYGHWHSDMESRGLYVPKCDVEGKKLIGKTTDGEFRFCYYVDKSKIGFSSFWFSEWQPKHPKGVRSLCGSSTVIYKDKLGDWYTEKELVAGFVYVCKANVLSSEDSYRDFDEQELNFIVAPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA3</accession>
    <name>A0A1D3RMA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription accessory protein (S1 RNA-binding domain)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_43415_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000217">
        <property type="protein sequence ID" value="SCN46689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="412"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="526" mass="57293" checksum="ED69EE5C253B769A" modified="2016-11-30" version="1">MPGADEKADHQLFAQIVARHIHVTDTSKAADTWLAETARFAWKVKLFTRIDLDLKQQLREAAELEAIKVFANNLKDLLLAAPAGPKATLGLDPGIRTGVKVAVVDTTGKLVATETIYPHPPRNQWDTSIATIAKLIKQYQVELVSIGNGTGSRETDQLVADLMKQHKDLKFNKITVSEAGASVYSASELASQEFPGIDVSLRGAVSIARRLQDPLAELVKIEPKSIGVGQYQHDVNQIQLARGLDAVVEDCVNAVGVDVNTASAALLKQVSGISNTISHNIVAFRDEQGAFKNRKQLKKVPRLGAKAYEQAAGFLRIMQGDNPLDASSVHPEAYPVIEDIVKKTGTPINKLIGKSNVLRHLNPTDYTNENFGLPTVTDILQELEKPGRDPRPEFKSVTFKAGIEKITDLKEGMRLEGVVTNVANFGAFVDIGVHQDGLVHISHLADVFVKDPREVVKTGDMVNVKVIDIDVARKRIALSMKKDAPVGEQVHLKADNAPPRKAHKPKPPVETPQSSMADAFAKALKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC8</accession>
    <name>A0A1D3RMC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00523_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="50" mass="5863" checksum="70FC32086E303119" modified="2016-11-30" version="1">MIYEWRTIGVFESKENLFLTGMNKETDVFEYISTPNVTTVGKAYLLNQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD6</accession>
    <name>A0A1D3RMD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_05000_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000317">
        <property type="protein sequence ID" value="SCN46842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022061">
        <property type="entry name" value="DUF3617"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12276">
        <property type="entry name" value="DUF3617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920253" evidence="1">
        <location>
            <begin position="23"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="15765" checksum="E9AF971C5623B3E5" modified="2016-11-30" version="1">MKMTKKISLVLLLPLSVASVFAQTPDIKEGLWEVSSQVSMAAMPMKIPAMTMQQCFTKQSMSPENILQQNNCQMHDLDIQNNQVRWSMNCEQEGMKMQGLGKIQYQKTSFSGTFDMTMSGAPQGAMAIQTKITGRYLGKCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMH3</accession>
    <name>A0A1D3RMH3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">BAZMOX_10183_1</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000264">
        <property type="protein sequence ID" value="SCN46759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="19"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="265" mass="29986" checksum="F38C88C973B10D83" modified="2016-11-30" version="1">MAHIARKRFGQNFLHDHHIISNILGSLAYNKNQHWVEIGPGQGALTESILNDGIQLDVVELDRDLVRFLDFKFRNFSNLTIHSSDALKFDFSALATQGEKLHILGNLPYNISTPLMFHLLENTPLIADMTFMLQKEVVDRICAAPGNKKYGRLSVMMQYYCATEHLFDVPPESFNPAPKVMSSIVRLMPYAQPPVIIDSIKSLNTVVTAAFSQRRKTLRNSLKKLILEANIIALDIDPTIRAECLSLEDFAKISQFVHQNPLPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI0</accession>
    <name>A0A1D3RMI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_11390_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000203">
        <property type="protein sequence ID" value="SCN46667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="11"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="198"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="371" mass="42565" checksum="02180E4AE4343BD6" modified="2016-11-30" version="1">MLISKKLKEKVIIIAESDPQLLAEIKLNLNKQGFLNIKTALDGQQIYEILRSYYGIAKKIGLLIVNEQLPQCDVLAMCQQLSSHDASLIPFIILSADENKHNIENSEFNSQALIHQMSYPINYSVLMDTIGFQLIMMQERYLRHKQEERLINELAERKIVDAKLKYLVVHDELTGLINRHNFESQLRLVLMRSRIRQQEGALIFINLDRFSLVNELEGFDVGDRLLIEIVAIIRKIIFKDDLFARIGSDEFCLFLDNKTAKEVKQFAERVRASVDEFKFSSGGVCYSTSLSIGIASVNTVTADYHPNEIISKARQACRMAKEHGRNMVWSYNETDTKVQERNKDLYWVPLIKKALLGEKVSSSISASCLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI1</accession>
    <name>A0A1D3RMI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02006_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000332">
        <property type="protein sequence ID" value="SCN46864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="133" mass="15225" checksum="8ED4B37AEA980955" modified="2016-11-30" version="1">MYEAYLSKKHDSHNTIHNILKKLFYLIAWGNKSGIDIDSILLTGEMIEPKQVNAFGAWLTQRGKLHADGTISPIAINGILDVVSQAFRWFADQYVSFSGSASEREIHIKMYKDSIKERFSEQCEKSRKKNSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK0</accession>
    <name>A0A1D3RMK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Redoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_11318_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000355">
        <property type="protein sequence ID" value="SCN46902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="31"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="173" mass="19503" checksum="7D7B89392C59CCA1" modified="2016-11-30" version="1">MPKPLLIFIFIFLILVSALFVNHQSQKEQQVLAPTPLIDFSLANLAGELTPISKWRGKILIINFWATWCPPCLKEIPDFITLQNEYADKNVQFIGIAIDTPELVADYLAFININYPILMAEVEGQQLAKQLGNRVNAVPFTLIVNANTRLFSSPGELSKAKIRQIIDPLIQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK4</accession>
    <name>A0A1D3RMK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrase, catalytic region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_368006_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000289">
        <property type="protein sequence ID" value="SCN46789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="105" mass="11742" checksum="3FC760B879FC6C29" modified="2016-11-30" version="1">MVTRDPNNGLQDLGNINLLLILAGFATMIDICQVKYLNNIIEQDPRFIKKITKPMMGFKAFHSAQATIAGIETAHMIRKGQLSEENIPAYKQFMALVNKTGMIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM0</accession>
    <name>A0A1D3RMM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgk</name>
        <name evidence="11" type="ORF">BAZMOX_114445_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="FMJP01000228">
        <property type="protein sequence ID" value="SCN46707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="345"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="390" mass="41190" checksum="C8CA87F65B505117" modified="2016-11-30" version="1">MPIKKMADLDLKGKRILIRQDLNVPVKDGKVTSDIRIRASIPAIELALKANAAVMLMSHLGRPTEGEFDSNASLQPVAQRLSELLNKPVRLQKDWIDGIDIQPGEVVLCENVRFNIGEGKDSAELGKKMAALCDIFVMDAFGTAHRAQASTHSVIKYAKVACAGPLLSAELDALGKSLSHPEKPLMAIVGGSKVSTKLTVLKSLAEKVDQLIVGGGIANTFIAAAGYSVGKSLYEADLVDDAKALIAAAKVNNSDIPIPVDVVCAKEFSDTAVATVKKVTDIADDDMILDIGPETAKQYAEKLATAKTIVWNGPVGVFEIEQFSNGTKVLAHAIADSSAFSIAGGGDTLAAIDKYAINDKISYTSTGGGAFLEFLEGKELPAITALETKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMM4</accession>
    <name>A0A1D3RMM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS2020, hypothetical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_86853_4</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000300">
        <property type="protein sequence ID" value="SCN46809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="125" mass="13987" checksum="6AC1EEA985B24FE8" modified="2016-11-30" version="1">MLSERRDEDAATAFFKQAINNNGFPDKVVMDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIIEQDHRFIKKTTKPMMGFKAFHSAQATIAGIETAHMIRKRQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP1</accession>
    <name>A0A1D3RMP1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_03651_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000246">
        <property type="protein sequence ID" value="SCN46727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="55"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="541" mass="60739" checksum="E1D9BE85E04C1257" modified="2016-11-30" version="1">MAYEYSDLVAEAKGWATEVITRSWASESKLHDLLNYEARTPESLFSGSSSRPLIIAFLGGTGVGKSTLLNRLAGQEIARTGVVRPTSKEVTLFHHTSVKITQLPSRLPIDKIKVAEHSDASKKHIIWIDMPDFDSTEKSNQQLVLEWLPHIDVLVYVVSPERYRDNKAWQLLLAEGGKHAWIFVLNQSDRGEVEQYQDFINQLHKAGFNNPIVYQTCCVTDKTLAQIDEFNALEAAMQTLATENTVKQLELRGGQVRKVELSKVLASALDVLGSPASSQVLIPFWRKQWQNFEGLLIDAMALPLQQLAEYYALHSSDLSAKELDNHSSHKIHHGLWDKWAQARLEDALDALIIQADSLELPIAPIKQAIQPVRENAQKMIADKTLLSVRKALINPGNVIQRALIKVAFVAEIILPIAAMGWVGYQVFIEFYEASLAEIPHYVGVNFAVNSAMLIAIAWLFPYFLKKKLKPSIEKAALKGLRNGLLGALQSIELEVVERIKQNAQIQEDLRQQAEKIMSACQEDNDNLFELPENSPLERMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS0</accession>
    <name>A0A1D3RMS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secY</name>
        <name evidence="13" type="ORF">BAZMOX_28573_0</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000385">
        <property type="protein sequence ID" value="SCN46936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN46936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="416" mass="45637" checksum="A1654F663C59CB2E" modified="2016-11-30" version="1">MRFFVYRVGAHIPVPGIDPQALALMFKQQEGSILDMFNMFSGGALKRLSLFALGIMPYISASIIMQLMTIVIPALEQVKKEGEAGRRKISQYTRYGTVFLATFQAIGVSIALQNQTAGGLSVVINPGIQFIVITAITLVTGTVFLMWLGEQITERGLGNGISLIIFAGIVAGLPSAIGGTLELARTGELNGAFIVLLFLLSMAVTALVVFVERGQRRIVINYPKRQQGKRMYAGQSSFLPLKLNMAGVIPPIFASSIILFPATIAGWFSSAEGFSWLQDISTTLSPGQPLYVMLYTVAIVFFCFFYTALVFNSKETAENLKKSGAFLPGIRPGEQTATYIDKVMTRLTLIGAFYITAVCLLPEFLIVYWNVPFYFGGTSLLIIVVVVMDFVSQMQTHLMSQKYEGLMDKANLKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT5</accession>
    <name>A0A1D3RMT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="5">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_04671_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000446">
        <property type="protein sequence ID" value="SCN47015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="3">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="4">
        <location>
            <begin position="111"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="259" mass="27944" checksum="8013D73ED43F0775" modified="2016-11-30" version="1">MGKDTRISGYMFESALEAGLAAAGVNTRLLGPMPTPGIAYLTRTLRAQAGIVISASHNPYYDNGIKFFSTEGTKLPDELEHKIEYYLDQSMITVESAQLGKAQRISDAAGRYIEFCKASIPASIDFSGLRIVVDCANGATYHIAPHVFREVGAEVIEIATEPDGLNINEKCGATKTDLLKNAVINYRADLGIALDGDGDRLIMVDDTGEEVDGDELIFIIAKARKVAGKLQGPVVGTQMTNLGMEHALKNLKLIYCALM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT6</accession>
    <name>A0A1D3RMT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Helix-turn-helix protein, CopG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_48536_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000425">
        <property type="protein sequence ID" value="SCN46983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046257">
        <property type="entry name" value="DUF6290"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19807">
        <property type="entry name" value="DUF6290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="75" mass="8548" checksum="2E9FAF1E0E16206F" modified="2016-11-30" version="1">MATSVRLNSEIEQRLNNLAAKTGRSKAFYLREIIEAGLSDMEDYYFAINTLERVRKGEEAVYSLDEVEKSLGLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX2</accession>
    <name>A0A1D3RMX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_86853_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000300">
        <property type="protein sequence ID" value="SCN46807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="84" mass="9416" checksum="CACF697DABA66E41" modified="2016-11-30" version="1">MDAMSYSAFRTNLASTLDKVNDNHKPVLITRQNGKPAVLISLEDFQSYEETSYLMSSPKNAERLNDAISQVEAGKVKQHELISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ1</accession>
    <name>A0A1D3RMZ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">trmD</name>
        <name evidence="17" type="ORF">BAZMOX_00434_3</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="23"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="134"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SCN47061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="248" mass="27921" checksum="4BAFF76822EDEB65" modified="2016-11-30" version="1">MRFDVVTIFPEMVLDCAMNGVTGRAIKQGLVDLAVWNPRNYTLDKHKTVDDRPYGGGPGMVMKYKPLKDAVDDAKKLGSKERVKVVYLSPQGKPITQQLLNENTALEQLILVAGRYEGIDERFIQNECHEEWSLGDFVISGGELAALVVIDAISRLLPGVLGDEGSAKQDSYMDGLLDCPHYTRPEVFEGKAVPEVLLGGNHKDIAKWRMKQSLGWTWQKRPDLLFNKELTAEQKSLLNEFKIELKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMZ6</accession>
    <name>A0A1D3RMZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_IS66_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_296629_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000464">
        <property type="protein sequence ID" value="SCN47043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039552">
        <property type="entry name" value="IS66_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13817">
        <property type="entry name" value="DDE_Tnp_IS66_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS66_C" evidence="1">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="47" mass="5768" checksum="486F4F81E6457C69" modified="2016-11-30" version="1">MRQNHLEPFDYLKYLLTELPKLGRHYEPEALDQFLPWNLTEKIKPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN67</accession>
    <name>A0A1D3RN67_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="6" type="ORF">BAZMOX_01036_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000535">
        <property type="protein sequence ID" value="SCN47130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="5">
        <location>
            <begin position="20"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="125"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="185" mass="20693" checksum="8DB9FC5010C2765A" modified="2016-11-30" version="1">MINDIEQDAASRMGKSIEALKKGFTKIRTGRAHPSLLDQVVVSYYGADTPLSQVANVSIDDSRTLAVTPWERGMIQAIEKAIMASDLGLNPVTNGNIIRVPLPMLTEERRRDLVKVVKAEAENGRVSIRNIRRDANNEIKEALKEKMISKDEAHAGEEKIQKITDQYIKQVEKLLEDKEADLLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN80</accession>
    <name>A0A1D3RN80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01036_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.7.41" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000535">
        <property type="protein sequence ID" value="SCN47132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="276" mass="30748" checksum="3F1F3AC465A24F7D" modified="2016-11-30" version="1">MVVLAIFKLPHLYFAIIWGVVLLIAAWEWANLAEVKTVLGKCLFLVAMLIPMVLLQFWTQLLEALAQLSNWPEIRTYSGLIEALVVPAVVFWIYVMFKIRRAGADLLDIKMGVGKKLWIGGFVLVSAWLFLSRLIVLEEPAMTLFLFILIWSADIGAYFAGKKFGKTKLAIEISPGKTLEGLYGALFASVVVGLVFTLYFNFSAMSIGDFLMLSVITVLVSVYGDLFFSAAKRIRGVKDSGMILPGHGGLLDRLDSVIAAIPVFYAGVWFIRWMYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN97</accession>
    <name>A0A1D3RN97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_274353_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000570">
        <property type="protein sequence ID" value="SCN47185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4164" checksum="7FFEF909B5284A38" modified="2016-11-30" version="1">MIGKVVKVGDFCIVFIGELINRQKAFVSIKTEVLAVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA8</accession>
    <name>A0A1D3RNA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Iron-sulfur cluster regulator IscR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_10865_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000426">
        <property type="protein sequence ID" value="SCN46988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="163" mass="17961" checksum="AD0286FFC69892C1" modified="2016-11-30" version="1">MRLTTKGRYAVTAMLDLAFHSQIKPVTLTDIATRQTISLSYLEQLFSRLRRAGMVTGVRGPGGGYKLSKETNEISISDIILAVDEQVDLTNCESKGNCQNDGPCLTHDLWMGLSNTVRNYLDGITLGELLAQEDVRAVAQRQDNDIAQTIHFKDTTTVGMALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB2</accession>
    <name>A0A1D3RNB2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-deoxy-D-xylulose-5-phosphate reductoisomerase</fullName>
            <ecNumber evidence="3">1.1.1.267</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_01036_6</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DXR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000535">
        <property type="protein sequence ID" value="SCN47134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_redisom_C" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="83" mass="9300" checksum="2EB1355F2C7448E2" modified="2016-11-30" version="1">MGRKISVDSATMMNKGLELIEACLLFNMQPEQIQVVIHPQSIIHSMVDYVDGSVLAQMGNPDMRIPIAHAMAWPDRLILELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB8</accession>
    <name>A0A1D3RNB8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lepA</name>
        <name evidence="7" type="ORF">BAZMOX_01012_6</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000580">
        <property type="protein sequence ID" value="SCN47205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="4"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="600" mass="66183" checksum="9504897A4213544B" modified="2016-11-30" version="1">MDLKNIRNFSIIAHIDHGKSTLADRFIQLCEGLSDREMSAQVLDSMDIERERGITIKAQSVTLNYTAKDGEVYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQSVANCYTAIELGLEVMPVLNKIDLPSADPEKVIAEIEDIIGIPAENALHVSAKTGLGVADVLEELVHTIPAPSGDENAPLQALIIDSWFDNYLGVVSLVKIVSGSLRKKQKITIMSTGKSFIAERIGIFTPKRVDTLELKTGQVGFVVGAIKDIYGAPVGDTITSTATPCTHALGGFKKVQPRVFAGLYPVSSDDYEDLRESLNKLRLNDAALQFEPESSQALGFGFRCGFLGMLHMEIIQERLEREYDVNLITTAPTVVYEVETHKGDLLYVDNPANLPDIGSIKMIREPIIQANILVPQDYLGNVISLCIEKRGVQMNMQYMGSQVSLHYELPLSEVVLDFFDRLKSVSRGYASFEYEFKRFQEAALVKLDILINGDRVDALSIIVHRDLSQSRGRDLVEKMKELIPRQMFEVAIQAAIGGKIIARSTVKSMGKNVTAKCYGGDISRKKKLLEKQKAGKKRMKQVGNIEIPQEAFLAVLQVNKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC7</accession>
    <name>A0A1D3RNC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_246542_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000574">
        <property type="protein sequence ID" value="SCN47191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="190" mass="22123" checksum="F8B5E7A40E0A8C4E" modified="2016-11-30" version="1">MIRHLLRPLSYLFIEHQLKWKVDWLYPFLLTIISTFLIFFLKQFGQVSLYYDGGMISKILGFVQVLPGFYIAALAAIATFNKTDIDKIMAAPAPKIDIFIHGKSVAIELTRRRFLCSMFAFLTAESLILIVLSIFATSLYVPFKEIIHESWHIWASGIFTIMFLLLFWQMIITSFWGLYYLGDRLHQPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNF7</accession>
    <name>A0A1D3RNF7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraZ</name>
        <name evidence="10" type="ORF">BAZMOX_00289_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="7">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MraZ family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000434">
        <property type="protein sequence ID" value="SCN46997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="10" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="5"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="87"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="17858" checksum="46E7F71FDD841777" modified="2016-11-30" version="1">MFRGVTAINLDAKGRCAIPSRYRDELQDCCERQLVVTVAVNERCVGEPGCLWLYPLPEWDKLELTISKLPTLDKMAGKLRRFVIGYATEAEMDAQGRILLPEKLRKFARMEKKLILVGQLNKFEIWNEVSWNAKEDEWMSGDQDDDLSEVSNLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG5</accession>
    <name>A0A1D3RNG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Epoxyqueuosine reductase</fullName>
            <ecNumber evidence="7">1.17.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Queuosine biosynthesis protein QueG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">queG</name>
        <name evidence="9" type="ORF">BAZMOX_36377_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the QueG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000577">
        <property type="protein sequence ID" value="SCN47194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00916">
        <property type="entry name" value="QueG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cob(II)alamin binding" evidence="7">
        <location>
            <begin position="245"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="353" mass="40224" checksum="A81C364D594AAAD2" modified="2016-11-30" version="1">MDKAMNELSQQIKHWGLELGFQQVGITDTDFHQAEQRLQHWVAQGYHADMEYMHKHGLKRSRPALLQPGTVSIISVRMDYLPEAQEPIENTLNNPVAGFISRYALGRDYHKVLRKRLQKLAQRIEQEIGIFGYRAFVDSAPVLEKAIAEKAGLGWIGKHSNIINKKAGSWFFLGEIYTSIPLTIDSPSHNHCGQCTACINICPTQAIIAPYQVDARKCISYLTIELKGSIPEALRSLMGNRIYGCDDCQLICPWNRFARLSTETDFSPRYNLNAQHLIELFNWSETEFLTKTEGSAIRRIGYEQWQRNIAVALGNAPASTEIKAVLNHKISYHSELVKEHVLWALKQEHVLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH2</accession>
    <name>A0A1D3RNH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_239599_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000509">
        <property type="protein sequence ID" value="SCN47099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5040" checksum="1B5443698538F0C5" modified="2016-11-30" version="1">MTPVRQACRVFNNSLIYCFNCLIKVSGVFCFGRYLSGVFPFLMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH7</accession>
    <name>A0A1D3RNH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA 5-methylaminomethyl-2-thiouridine synthase TusC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01012_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DsrF/TusC family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000580">
        <property type="protein sequence ID" value="SCN47204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017462">
        <property type="entry name" value="Sulphur_relay_TusC/DsrF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38780">
        <property type="entry name" value="PTHR38780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03010">
        <property type="entry name" value="sulf_tusC_dsrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="119" mass="13436" checksum="B6BB3D5BBC077195" modified="2016-11-30" version="1">MNKSFLFVMQTPAYSGTKVQEVLDVVLITAAFDQKVSLLLLDDAVFHLKNKQQNMALISKDIGAIYRSLELYDIESIYVEQESLNYTGLSVSDLLIPIKLIARRKLPALLHSFDFVLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS3</accession>
    <name>A0A1D3RNS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_20421_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000639">
        <property type="protein sequence ID" value="SCN47294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="62" mass="6997" checksum="16565169718297F7" modified="2016-11-30" version="1">MNSTLGWLLAILKAVVVLFILGIAKVTLRTNPDIAFPVLGAAVMFFLIWYFAPQIKRYLNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU0</accession>
    <name>A0A1D3RNU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_26807_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000652">
        <property type="protein sequence ID" value="SCN47306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="94" mass="11105" checksum="32E7F0E2B7A925A5" modified="2016-11-30" version="1">MQHNKPDWMNEEEQRAEDLTEKEETSNNTAPQLVRVNKAPPRMQKAFYIQEKYAEAFNDFVYKQKKKKGKKAPELAEEAIKMLLKKYGEDTINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY0</accession>
    <name>A0A1D3RNY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
            <ecNumber evidence="6">5.3.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_48678_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000583">
        <property type="protein sequence ID" value="SCN47208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="154" mass="16453" checksum="F4313CD863F34ECD" modified="2016-11-30" version="1">MQYVIIGTKAVSDPLFVRELAMAYPGHIIVGLDAKDGKVAVDGWSKLSRHDVIDMALKFESYGVEAIIYTDISRDGMMNGVNVEATAKLADAINIPVIASGGITNIEDIKALALAAEDGIMGAITGRAIYEGSLDFAEAEKLAQSFPKGHYEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ2</accession>
    <name>A0A1D3RNZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_21766_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000587">
        <property type="protein sequence ID" value="SCN47218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="75" mass="8899" checksum="348D2F397E4A70D5" modified="2016-11-30" version="1">MIKIPYIHVPAVNPITKPKKVIRYATIIDEEEQPPEVKTERRKRPTRRTSSKRMKQIVNRRVSSDRRKASFNEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP24</accession>
    <name>A0A1D3RP24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugal transfer protein TrbG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_16045_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrbG/VirB9 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000715">
        <property type="protein sequence ID" value="SCN47396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06911">
        <property type="entry name" value="VirB9_CagX_TrbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010258">
        <property type="entry name" value="Conjugal_tfr_TrbG/VirB9/CagX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033645">
        <property type="entry name" value="VirB9/CagX/TrbG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038161">
        <property type="entry name" value="VirB9/CagX/TrbG_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03524">
        <property type="entry name" value="CagX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="134" mass="15355" checksum="31A97755D3FC239A" modified="2016-11-30" version="1">MSAVSWIYAQDELDLYSAQAEEIRRENEMIQTSSVDISHANFNYTIEVDEGSPVWKPVRVFDNGKKTYIQFPDALASSEAPALYVLKHGDLQMVNYRVKENYYIVDRLFNQAELRIAQEGGEEIVLIMNDNKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP34</accession>
    <name>A0A1D3RP34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_261720_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000730">
        <property type="protein sequence ID" value="SCN47406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="3"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="268" mass="31351" checksum="A5B78700AB6B9954" modified="2016-11-30" version="1">MSEQRLILGCISKIKSDESMLRKSNGKNISLSKNYEEYELSVNEYSETFGLSRKEAYNELLRISDKLYHRDLKIKNKNGSITKTRWISSITYNPDDAVISIEFAPKIVPYLTLLEREFTKYRLEHVSNMTSLYAIRLYELLAKHQFQEIKEINISVSELKTMLLVENKYKLFGHFHDRVIKPAVEQINKHSNFIADYELIKKSRSFSDIKFKFKLKNPLKKISDKAEIITITNEIIDKNARPGETKYVVATRLVASGKYKHAQRKTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP38</accession>
    <name>A0A1D3RP38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_44336_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000586">
        <property type="protein sequence ID" value="SCN47217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="163" mass="18514" checksum="B1495383384C1F0C" modified="2016-11-30" version="1">MTDLAGPTSIKMDCHDYINVFCIYAAHSGELETVSEETLDILKKELEIPKECLNLGEYAVLVTNVPQFIDRIKKAVMDKNYKMTSGLVTYYDPDTFHGNFFEDEPIFRKQDGYKHQKEYRFAFDTGLVGDDPLILNIGNISDIAVKCKVSDVNNGLNIKFLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP39</accession>
    <name>A0A1D3RP39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_45768_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000732">
        <property type="protein sequence ID" value="SCN47414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4912" checksum="9250D819324FDCDC" modified="2016-11-30" version="1">MDETYIKMKGIYTEPLIVTVIRLISCCLSAVIEDAATAFFKQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP50</accession>
    <name>A0A1D3RP50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_47247_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000772">
        <property type="protein sequence ID" value="SCN47463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5474" checksum="F80DB2C0CBA349C7" modified="2016-11-30" version="1">MLAQQQLTGAFLAEQIIYCSTRLEAMAKAARQSAKMNATELVAEQCIEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP52</accession>
    <name>A0A1D3RP52_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Znf/thioredoxin_put domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01131_5</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000799">
        <property type="protein sequence ID" value="SCN47515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021834">
        <property type="entry name" value="DUF3426"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011723">
        <property type="entry name" value="Znf/thioredoxin_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11906">
        <property type="entry name" value="DUF3426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13717">
        <property type="entry name" value="zinc_ribbon_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02098">
        <property type="entry name" value="MJ0042_CXXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Znf/thioredoxin_put" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="200" mass="22727" checksum="7CC61B0DC6F9A0D6" modified="2016-11-30" version="1">MYAVCPKCHNSQAISAKQLQKKRGKVICSQCKHSFNPRTSLSDRPVKAINKNEVKPYAWQKTVNSHSKLWLTSSLLAALLLVYQIYYFKGYSLAQSAQIRPWLQSISSAINYPLPHYRNTSEFTTIGSSFTPIKNNHFRLQVSFINHANFSQALPNLNLTLQNLHGGIIAQRIFTPKDYLTQDITTPPSLRVTTLSILIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP84</accession>
    <name>A0A1D3RP84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_19938_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000764">
        <property type="protein sequence ID" value="SCN47456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5122" checksum="43D3A114EFC9B529" modified="2016-11-30" version="1">MLWRGYEANEEFGVFLYALHGVFCLENKLSGQFVTEAFTFKINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPA2</accession>
    <name>A0A1D3RPA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_19097_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000804">
        <property type="protein sequence ID" value="SCN47530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4825" checksum="F4C04B03C82C48E7" modified="2016-11-30" version="1">MEEALAKWRGMPDGDSICSLIESIDLSVVNDVISIVDTKGRCEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB7</accession>
    <name>A0A1D3RPB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_395255_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000817">
        <property type="protein sequence ID" value="SCN47550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5620" checksum="534BB318B8B14609" modified="2016-11-30" version="1">MDETYIKVKGKWVYLYRAVDSHGDTLDFMLSERRDEDAATAFFKQASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPC1</accession>
    <name>A0A1D3RPC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00950_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000793">
        <property type="protein sequence ID" value="SCN47496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="165" mass="18723" checksum="A9CFD2E080FFD6C2" modified="2016-11-30" version="1">MTRFTLATGLRESNVLELEWSQIDLQRRVAWIHPDQAKAGKAIGVPLNDDAIAVIKLQIGKHSARIFTYKGVPIKKAGTAAWRKALVRAGIINFRWHDLRHTWARWHVQNGTPLHILKELGGWSSFDMVQRYAHLAPEHLAEYANNSSASCKIVAEENKTRLRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE0</accession>
    <name>A0A1D3RPE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_30766_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000828">
        <property type="protein sequence ID" value="SCN47561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="126" mass="14340" checksum="C05018AF993252D8" modified="2016-11-30" version="1">MKFKQLTDNKWQLLDYKRRVPMLGILKVELILTEEQPIQGFLKVTWGGGACTKISSIRHELIGNTIEVFIDTIETSPDCTRQYVTSKDIIPLPLYKLKSGEYKYTVNGGFEGVFSLSSDNYLADDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE5</accession>
    <name>A0A1D3RPE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_227839_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000790">
        <property type="protein sequence ID" value="SCN47492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="5004" checksum="CF8C9B3D90E541FE" modified="2016-11-30" version="1">MLFLYEFYPTHAQQLVIIWWMDSCIPKEEVDCQNTQLDIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE6</accession>
    <name>A0A1D3RPE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Response regulator receiver modulated metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_111148_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000800">
        <property type="protein sequence ID" value="SCN47516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="179" mass="20020" checksum="BDA8E9D365CDFF96" modified="2016-11-30" version="1">MAKKLQSQPKFSAILDDKTIELLYKSAPLHDIGKIAVPDHILKKPGKLTAEEQLEMQKHTIYGGDALKIAEKRSGSSSFLKFAREIAYSHQEKWDGSGYPEGLKGEQIPISARLMALADVYDALVNKRIYKPAFSHQEAVDYITQEKGKHFDPDMVDAFIQIEAEFARITLQCNKGLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE8</accession>
    <name>A0A1D3RPE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_43592_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000735">
        <property type="protein sequence ID" value="SCN47419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="98" mass="11217" checksum="246209765150A269" modified="2016-11-30" version="1">MLYINPIIYAEISAGFSRVEDLENALPIDYIQRENLPYEAAFLAGKCFVKYRRAGGKRRSPLPDFYIGAHAAVNEWSILTRDKGRYQSYFPTLKVIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH9</accession>
    <name>A0A1D3RPH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MG(2+) CHELATASE FAMILY PROTEIN / ComM-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_10012_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000806">
        <property type="protein sequence ID" value="SCN47532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mg_chelatase_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5449" checksum="5ADD2DDDA5269BF6" modified="2016-11-30" version="1">MNSFGLSHRAYHRILKLARTIADLAGSQNIEIPHLSEAIGYRKLDRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK1</accession>
    <name>A0A1D3RPK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_164073_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000882">
        <property type="protein sequence ID" value="SCN47630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="1">
        <location>
            <begin position="37"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="104" mass="12030" checksum="02C03D86EED3534D" modified="2016-11-30" version="1">MKERGLNVDHATINRWVIRYAPIIAEKAHSQKQKTKRSWRLDETYITVRGKWTYLYRAVDSQGDTLDFMLSEIRDEDAASAFLKQVINNNAFPDKVVIDKSGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL3</accession>
    <name>A0A1D3RPL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UPF0182 protein AF1421</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_02898_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000884">
        <property type="protein sequence ID" value="SCN47633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005372">
        <property type="entry name" value="UPF0182"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39344">
        <property type="entry name" value="PTHR39344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03699">
        <property type="entry name" value="UPF0182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="621" mass="71380" checksum="F9989B7D51E83B5F" modified="2016-11-30" version="1">MAKYCFFFALFVAAVIYIFSPKHRSVIPMFAALGGLLLALGLQNVAFIPSLINSLIVRPNPVLTEGQFMQSNIDATLNAYDINNIETVDYKINLDAADDITRWSTQKHFENIPVWDREFLKDVYQQLQGLRPYYNFQSVDEDRYYLSGHTQQVNLSARELNINKIPEAAKSWENIHLRYTHGYGAVVTPAAQDAGKPIVWYLRDLNMHSDVELAVETPDIYYGEEKYTYAIVPNKLDILGLSDSGQDVNSSYKGGSGIPFKSLFRKLLLAIYFSDEKIFFSTNISAQSKILLRRNIVDRVTRLTPFLHLDKDPYLVITKGRFYWIQDAYTLSDKYPVSKFASDNFLSGTKDFNYIRNSVKIMIDAYTGSVKYYIAEPDDPIINAYRVAYPGVFKQLEDIPSDLRRHLRYPRELYFMQMMVYAKYHQTNPNLFFEQAETWQFAKVNKKSIMPYYQTMDFGHCNNREEFVMINPMTPINRSNLSMIGVAGIFDTKSCEADSYKPNIKVYKFKRDVQVNGPAQVEALIDQDPVISEQFTLWDQHGSNVEKGRMVILPMGENSILYVQPIYMIATKTKIPELTRVIVSIGNEVVMARTLRVAFKKLKEKFEQGAKETSKTGISIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPM9</accession>
    <name>A0A1D3RPM9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PpiC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_07964_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000929">
        <property type="protein sequence ID" value="SCN47695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="141"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="311" mass="33940" checksum="37ED5F2837A295FE" modified="2016-11-30" version="1">MKLKLIPFLLAGTALVSGCQQNANTISAPSIQKEDAIAVVNGQFISKADLETLTKEVSARARGQKIPTDKLVDELVKRELLVQEAKNKHLDRSAEIIERLNMMKNALLSQAAIEDYIKANPVTEAELKAEYDKQIGRVAGGTEFKARHILVKTEDEAKAIIAELDKDADFAKLATTKSTGPSKAQGGDLGWFGAAQMVAPFSEAVAKLENGKYTTTPVKTQFGWHVILREDSRQQTPPPFEAVKAQLEPMVKRQKLTAYLDALRKGAQVEILVPLTEEKPAEVIEAVEVTESADGKTAEVIEAVEIIEPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN3</accession>
    <name>A0A1D3RPN3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ALS_ss_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_117158_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000902">
        <property type="protein sequence ID" value="SCN47660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ALS_ss_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4211" checksum="DADC6AF35DABB4D0" modified="2016-11-30" version="1">MTGPSDKLDAFVAALDENNIIETVRSGPTGLSRGEKGLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPR0</accession>
    <name>A0A1D3RPR0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide methionine sulfoxide reductase MsrB</fullName>
            <ecNumber evidence="3">1.8.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Peptide-methionine (R)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">msrB</name>
        <name evidence="5" type="ORF">BAZMOX_253380_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000742">
        <property type="protein sequence ID" value="SCN47427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01400">
        <property type="entry name" value="MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="4">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="130" mass="14528" checksum="A26E757AB91CD64E" modified="2016-11-30" version="1">MTDIKLSEEQWREKLTPEQFEVCRCSATEAPFTGKYVDCKTDGVYQCRCCGQGLFDSASKYNSGTGWPSFSDILSENTVKEVIDSSHGMRRVEVVCSACDAHLGHVFEDGPEPTGRRYCINSASLDLKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV4</accession>
    <name>A0A1D3RPV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_158427_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000952">
        <property type="protein sequence ID" value="SCN47733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920265" evidence="1">
        <location>
            <begin position="22"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="229" mass="25851" checksum="7BAE18AD50122904" modified="2016-11-30" version="1">MKTKNVLLAGLLITFSVSALASEIEDLGAQAMAEVRELIADTKVDISQELFGKDWVINNAQELIDLGTDIYYGAEIPGYHGKKIINGMNKQMYGKFSISRVVPNAHENLKKSVWIARIRIEREESQRRQKIEDALCSINGEYVNMPLIKLAGNDKRYSGKFLYRDGDLKLLDFQEIPVDDSLEPTVVFNDQTGVMVISICKVGDENYYAELQVMDDGITFDVTKAIRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-02-10" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPW0</accession>
    <name>A0A1D3RPW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_253210_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000958">
        <property type="protein sequence ID" value="SCN47743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="136" mass="16045" checksum="5D693F4AC8FCA928" modified="2016-11-30" version="1">MYWVAVIDWYSRYVLSWELSNTMDTTFCIGALEKALDVSTPTIFNTDQGVQFTSLSFTTALLNKGIKISMDGRGRALDNIFVERLWRTVKYENIYMNDYQTVPELRSGLKHYFEFYNQERLHQSLDYQTPSEVHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX2</accession>
    <name>A0A1D3RPX2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell division protein BolA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_07964_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000929">
        <property type="protein sequence ID" value="SCN47696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="88" mass="9455" checksum="407403F297B439A1" modified="2016-11-30" version="1">MTIDLIKTLLTNALAPESLELADNSHAHAGHAGAQSGGGHYHVRIVSSAFDGKSMVQRHQLIYNALGDLMKHEIHALGIEAFTPTELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX8</accession>
    <name>A0A1D3RPX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nickel transporter UreH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_23642_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000914">
        <property type="protein sequence ID" value="SCN47672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="88" mass="9215" checksum="363C1492A929E9CB" modified="2016-11-30" version="1">MHGMAGSAALIILTLQSVDSVMTGMLYILMFGIGSIIGMAALSFIIAIPLRHSAKGITWLNNSLQIVIGLVTIVLGTTLVYDIGGQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPY2</accession>
    <name>A0A1D3RPY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamyl-tRNA synthetase</fullName>
            <ecNumber evidence="6">6.1.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_15333_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.1.1.17" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000942">
        <property type="protein sequence ID" value="SCN47714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="5">
        <location>
            <begin position="3"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="4918" checksum="9EFF85D2C376D7FB" modified="2016-11-30" version="1">MSVKTRFSPSPTGYLHVGGARTALFSWLYAKKITGALFCVSKILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ08</accession>
    <name>A0A1D3RQ08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_67469_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000990">
        <property type="protein sequence ID" value="SCN47780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="342" mass="40087" checksum="A3FEB02284B913DB" modified="2016-11-30" version="1">MPMKEPPEESIKSVQYDLFTQFLSNNKNDVSNMVEVWESIPKYFFTPRQISQLRTEGGLAEPYKWNFSYNDSPCTVKIQPALIEQENGKYKAFFPSVTEELVEEALKKIFTDQQFGIHNPQKTESWVRFTLGMIQKELKNRGRSRDKKQIKHAIEVMSSCVITLYKEEKEIWKGSILQDLVSVNRHDYLADTNSQHIARLPLFISHSVNTLEYRQFNYERLMSCNEQLTRWIYKQLINRFKQANLMNTYHFMYSKVYRDSGLLQQKTEDKNRQKVRSSLTELIDRGVIANFTEDIRKKGRKIVDVKYTVSPTTNFVSEQKAANKRCKDGKTKALSVGIQIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ14</accession>
    <name>A0A1D3RQ14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_113592_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000841">
        <property type="protein sequence ID" value="SCN47588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="258" mass="29597" checksum="F8792C632440CCC5" modified="2016-11-30" version="1">MNLNALKNTEELQSFLNGSQAVAFSLPGKKEERYAFIQSTLKQFHYRAITKRQKGVVIRFLLQVTGYSRQQLTRLINQYLNTGAVQLKKVHKPPGFKQKYNATDIALLAKRDERYDTPSGAVIKKLCERAYCIFNDDDYKNIANISVSHLYNLRHSAGYQKQRRRFDKTKSRQVAIGERRKPNAEGTPGYIRIDTVHQGDQDGIKGVYHINAVDEVTQYEVVLSCERISEQFLIPVLTEMLEIFPFNMSGFHADNGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ16</accession>
    <name>A0A1D3RQ16_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_13765_0</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000940">
        <property type="protein sequence ID" value="SCN47712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="6">
        <location>
            <begin position="2"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="7">
        <location>
            <begin position="42"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="116" mass="13037" checksum="B08BAB9CCA1CB290" modified="2016-11-30" version="1">MTVGYMHMLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVTGRTRMYKNIVDGNHQMEAGMPESFNVLLKEIRSLAINIEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ25</accession>
    <name>A0A1D3RQ25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_02140_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000854">
        <property type="protein sequence ID" value="SCN47598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="PTHR10266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920262" evidence="8">
        <location>
            <begin position="20"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="36"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="240" mass="26961" checksum="E486A556450B3D28" modified="2016-11-30" version="1">MKKLLQICLLLLVPLGAFASAGIELEDADIDLTDHQSLENGAHLYVQYCLGCHSTKYIRYLNLADDFNIDQQEILKKVAPEGAGIYDKMLTAMNGHDAKKWFGTTPPDLSLIARSRGEDWLVSYLKGFYQDTSKQRGVNNTVFPDVAMPNPLWQLQGVQKAIIKTIDGREVITGLVITEPGTMTAKQFDKAVNDIVAFLVYAGEPAQVQRRSMGKYVLLFILMFGVIAYLLKKEYWKDVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ34</accession>
    <name>A0A1D3RQ34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Porphobilinogen deaminase</fullName>
            <shortName evidence="6">PBG</shortName>
            <ecNumber evidence="6">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="6">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hemC</name>
        <name evidence="9" type="ORF">BAZMOX_00676_6</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 6">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="6">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="7">
        <location>
            <begin position="6"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="8">
        <location>
            <begin position="226"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="6">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="308" mass="33254" checksum="F69B553F43E1DDD6" modified="2016-11-30" version="1">MTQRIIKIATRQSALALWQAEYVATRLKQAYPDIQTELVKMLTKGDKILDAPLAKVGGKGLFVKELEQGMLDGVTDIAVHSMKDVPMDFPEGLHLSVILPREDPSDAFVSNKYSSLEDLPANAKIGTSSLRRQCQISARFPGAQVLSLRGNVNTRLAKLDADDYDAIILATAGLMRLDFTDRITQRLDTSVSLPAVGQGAVGIECRVDDVEINQLLAVLQDKDSCITVGAERAMNNRLNGGCQVPIAGFAELKGDHLFMRGLVGKPDGSLIYRSEKTGSASEAEVIGRAVADELLASGAGEILRELYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ43</accession>
    <name>A0A1D3RQ43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_57133_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000957">
        <property type="protein sequence ID" value="SCN47742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="50" mass="5895" checksum="BFBBB02226EBE4D9" modified="2016-11-30" version="1">MQGKIWSSHSVQDRIWSNYSVQGRIWSNYSGQDGIWSNYSVQNWCNITLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ48</accession>
    <name>A0A1D3RQ48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_25418_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001015">
        <property type="protein sequence ID" value="SCN47820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="278" mass="32133" checksum="096A3CC259187B53" modified="2016-11-30" version="1">MKKILLLVYLLSYDVAASTLREDLAQLSETVVQMKHQADEVRKQSYAQTLVKKIWPSAVEARDRLKVFHTAAEKVRLIAYKNMRFEGMMNRRPGSLYGLSELAEEKYSGLTSTVMWALSVATRASNKATNLSGELDRAKAAKDWALRILQTTDHVRAKIYLKNVIYNLSFYKKDVDKSIKDAATLRTWAVRELSRISDLVEYLSSDNIEKRHILAYKVADDYLADQTEVIMEIYEEIDRQYKIREKKILSEVNFSMDQARILQLNVNMMEKFSTGLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ49</accession>
    <name>A0A1D3RQ49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_170809_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000911">
        <property type="protein sequence ID" value="SCN47669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="161" mass="18278" checksum="61C72E821DFA73C8" modified="2016-11-30" version="1">MKDFQLDGCYQRVCDALQKHHIHGSLLELEITETMLAKNTEQCISLMSRLQKMDIKFSVDDFGTGYSSMSYLKKFPINTLKIDRAFVSECDVNKEDAAICRAIVALGKSLGLKIIAEGVETQSQLDFLKQTECDVYQGFLFSRPLPVDEIDALLIENIFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ56</accession>
    <name>A0A1D3RQ56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01663_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000963">
        <property type="protein sequence ID" value="SCN47752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="305"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="366" mass="39611" checksum="3B2FADB677778653" modified="2016-11-30" version="1">MLTDSPTKFWLALLRTPGVGSKTFLKCLAYYTPEQLFSEPRETLLQLGLRGKSIDAIKAPDWQNVEQDLAWLEQPNNHILLFSDTDYPAQLKEIPDPPPILFARGDIDLVHFPQIAIVGSRNPSSLGIQVATDFAHSLSTAGFTITSGLALGIDAASHRGALSAHGKTIAVTGTGLDRVYPATHKQLATDIVNNGVLISEFPPGTSAKANHFPRRNRIISGLCVGLLVVEAAKQSGSLITARMALEQNREVFAIPGSINNPLARGCNSLIREGAKLVETTQDILDELAHLFQPSTTQVNASPISTQPSLAPEQQELLNYIQYSPTSIDQLVTESGFSVENIASHLLILEIQGYISPMNGGSFTRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ80</accession>
    <name>A0A1D3RQ80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0434 protein BAZMOX_35365_2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_35365_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0434 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001079">
        <property type="protein sequence ID" value="SCN47905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01187">
        <property type="entry name" value="UPF0434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="58" mass="6551" checksum="FFCF739288D40234" modified="2016-11-30" version="1">MLDILACPICKSSLVYDKAAQELICKADRLAFPVRDDIPVMLEDEARVLTSEEIEQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC5</accession>
    <name>A0A1D3RQC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_35365_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001079">
        <property type="protein sequence ID" value="SCN47903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="130" mass="15057" checksum="78A7FA2451D29A13" modified="2016-11-30" version="1">MTEDYITLYDKSYTYANIQTEADEYIRLEAASQGFALKVLVNDQSALVRSTVARIKYGHEQLAKDESWKVRATVAKHCLPTILKNLIYDENHFVRYIIVKRGYFLEHFTCDIDEEIAALAKYQLSIKANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD5</accession>
    <name>A0A1D3RQD5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_49013_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001085">
        <property type="protein sequence ID" value="SCN47913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4774" checksum="7FA252177DAF0B36" modified="2016-11-30" version="1">MVFTKRRFVSILGSVAANHGERMRGLVVRDSRRAVVLSESER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE0</accession>
    <name>A0A1D3RQE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_13384_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000985">
        <property type="protein sequence ID" value="SCN47769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="73" mass="8331" checksum="66A6139B41E6F53B" modified="2016-11-30" version="1">MDTLVNKHGVKLMPLPDDVLRKLKTLSEEVVLELANKDPMAQKIYQSFNQFRTQVAQWSALSEQAFLSARALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE7</accession>
    <name>A0A1D3RQE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Outer membrane lipoprotein carrier protein LolA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_264797_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000934">
        <property type="protein sequence ID" value="SCN47708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35869">
        <property type="entry name" value="PTHR35869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03548">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="100" mass="11113" checksum="CD2129915FCB6FE0" modified="2016-11-30" version="1">MIRPAFSYLSGSVKLAEKYTITQHAQDGDVLWLKLTPKNTESSFKYILIGLKKGVLYGMELSDNFGQLTQIIFSNVTTPETLDASLFEFVAPEGTDVFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQM5</accession>
    <name>A0A1D3RQM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RepA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_29456_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000970">
        <property type="protein sequence ID" value="SCN47757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018777">
        <property type="entry name" value="Replication_initiator_prot_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10134">
        <property type="entry name" value="RPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="342" mass="39507" checksum="F7D146EE1B57C698" modified="2016-11-30" version="1">MANPLLPVRHPEKDLFICDFGEVIPKSDIASMEHPLFTLSTKPDTAIRNYEHNGNTVRIAPSAYGLATIHDKDILIYCISQLMAGLNQGETPSRKIRFKAHDLLVTTNRQTSGQGYKLLRQAFDRLHGTSITTNIKTNGQEVIEGFHIIDAYKIVIDDPKTKRMIELEVTLSEWLYNSVIGEEILSIDHDYFRLRKPIERRIYEIARKHCGKQKQWHIGLKNLHKKVGSSGNIRLFKQSVNHITKHNHLPEYNLRIEGENVIFNYKDYQEKTAITAKQDSRPLIKPDTIEKVKRVLGRHFDVYALESEWLNWWEQSGKPELQSPDGAFFNFCKARMEKTQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQS0</accession>
    <name>A0A1D3RQS0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusG</name>
        <name evidence="9" type="ORF">BAZMOX_30461_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001018">
        <property type="protein sequence ID" value="SCN47827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="2"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="177" mass="20593" checksum="BF5794DEAF235BF8" modified="2016-11-30" version="1">MAIRWYVVHAYSNYEKKVKQSLEEKIQREGLEEFFGKILVPTEEVVEMRMGQQRKSERKFFPGYVLVQMELTDETWHLVKDEPRVLGFIGGTSERPAPISNQEAERILNRVEEGVNKPRPKVLFEVGEVVRVNDGPFKDFNGEIEEINYEKNKLKISVLIFGRSTSVELGFNEVEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL48</accession>
    <name>A0A1D3RL48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">General secretion pathway protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_99537_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000012">
        <property type="protein sequence ID" value="SCN46401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="217" mass="23694" checksum="A26C1E7F8A6493F6" modified="2016-11-30" version="1">MTVEDPIEYEITGAAQCEIDTNSEKVTFNSALRSILRHDPDVVMVGEIRDKETAEIAIKAALTGHMVLSTLHTNSAIATITRMVDMGIAAYLVAAALRVVIAQRLLRRLCAYCRIERPLTVMEASIINRADLAGTLIYEPSGCVYCANKGFKGRIGLYELLELRPEWIKAVSEGAREPELLAMMQAAGINSLLEDAVGKMLAGDTSYSEVMQVAASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL52</accession>
    <name>A0A1D3RL52_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_33689_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.1.1.20" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000041">
        <property type="protein sequence ID" value="SCN46445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_2d" evidence="2">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="76" mass="8645" checksum="94D2338CC3EB8044" modified="2016-11-30" version="1">MCDGKGCRVCSHTGWLEVMGCGMIHPEVFKAVNIDTEAYTGFAFGMGVERLAMLRYGINDLRLFFENDLKFLEQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL84</accession>
    <name>A0A1D3RL84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04471_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000015">
        <property type="protein sequence ID" value="SCN46404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4341" checksum="09DE457868093D6F" modified="2016-11-30" version="1">MFDTDGKFGKYEHRVKLVANRLGVKFNWIKNESLGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLC2</accession>
    <name>A0A1D3RLC2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SoxAX cytochrome complex subunit A</fullName>
            <ecNumber evidence="11">2.8.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Protein SoxA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Sulfur oxidizing protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Thiosulfate-oxidizing multienzyme system protein SoxA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BAZMOX_93501_1</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>2 Fe(III)-[cytochrome c] + L-cysteinyl-[SoxY protein] + thiosulfate = 2 Fe(II)-[cytochrome c] + 2 H(+) + S-sulfosulfanyl-L-cysteinyl-[SoxY protein]</text>
            <dbReference type="Rhea" id="RHEA:56720"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14328"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="Rhea" id="RHEA-COMP:14691"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="ChEBI" id="CHEBI:139321"/>
            <dbReference type="EC" id="2.8.5.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>2 Fe(III)-[cytochrome c] + S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate = 2 Fe(II)-[cytochrome c] + 2 H(+) + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein]</text>
            <dbReference type="Rhea" id="RHEA:51224"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="Rhea" id="RHEA-COMP:14689"/>
            <dbReference type="Rhea" id="RHEA-COMP:14690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33542"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:140664"/>
            <dbReference type="EC" id="2.8.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="13">Binds 2 heme groups per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterodimer of SoxA and SoxX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 11">Belongs to the SoxA family.</text>
    </comment>
    <dbReference type="EC" id="2.8.5.2" evidence="11"/>
    <dbReference type="EMBL" id="FMJP01000040">
        <property type="protein sequence ID" value="SCN46444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016669">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019417">
        <property type="term" value="P:sulfur oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025710">
        <property type="entry name" value="SoxA"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038455">
        <property type="entry name" value="SoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04484">
        <property type="entry name" value="thiosulf_SoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 11 13" id="KW-0349">Heme</keyword>
    <keyword evidence="7 11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0574">Periplasm</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920215" description="SoxAX cytochrome complex subunit A" evidence="15">
        <location>
            <begin position="24"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="12">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="13">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="13">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="13">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR038455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038455-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038455-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038455-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SCN46444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="279" mass="31772" checksum="3F1297EE64353680" modified="2016-11-30" version="1">MNSPLFIFCLWINLLISSSLTWASPEQDRKQILTFYQQLFPQLQFADYAQGVYAIDSDAKSSWQAIEEFPPYEFALEEGKTLFNRPFNNGVRYADCFPNKGIAIAQNYPYWDEHKQSVITLASALNDCRLQNHFPALPYAKGEITKLLAYMAFTSRGQLIRTIIPEHSPQALNAYEQGKAYFYQRRGQLNFSCASCHIDNAGKFIRSEILSPALGHTTHWPAYRLNTGEMGTLHRRFIACNKLIRAPIDAAQSPALRQLEFFLSYIANGLPLNGPSTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-06-17" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLD6</accession>
    <name>A0A1D3RLD6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_61653_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000104">
        <property type="protein sequence ID" value="SCN46525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="117"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="175" mass="20007" checksum="8AB65E0D67435457" modified="2016-11-30" version="1">MRQMGGLMQKNIRARDTLARLGGDEFAILMEHCGLFQANQAAEHVIHALEKFRFHWEEHTFTIGVSIGLAIIDQYTKDSQEILSQVDSACYAAKDAGRNRIEVHTENSERLKQRKGEIKWSSEINDALDNNRFLLYVQPIVPILNKELKMGYEVLLRLKNAGWKNRPTGGFFTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLE3</accession>
    <name>A0A1D3RLE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Copper resistance protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11757_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000058">
        <property type="protein sequence ID" value="SCN46464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="166" mass="18297" checksum="502E72D4D4527E58" modified="2016-11-30" version="1">MVKIILLAIALGFAWLNRRAVLEYKISANPYALFNRVPYYIEAETFVLITLLFTAASLASQPPAIDIPGLTATWMEALNAFAPRIPHLSSPSHEALLAGEAGRTAILNQVPSVASTEWSDYNHNIAGVFVVVMSLLAMLSYKKSFTWARYWPVGFIGLGIFSFIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLF0</accession>
    <name>A0A1D3RLF0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_275694_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000072">
        <property type="protein sequence ID" value="SCN46492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="108" mass="11935" checksum="458AC4839065575D" modified="2016-11-30" version="1">MHLDAMEHGDKIVFLHAVKEGAASQSYGLQVASLAGVPKTVIEQAKLKLRHLESSAYKEQQTEIGSTQLDLFAINEPHPAIELIEKLAPDELTPRQALDFLYALKQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLJ1</accession>
    <name>A0A1D3RLJ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ettA</name>
        <name evidence="10" type="ORF">BAZMOX_10816_2</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000144">
        <property type="protein sequence ID" value="SCN46575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="PTHR43858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="6"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="324"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Arm" evidence="7">
        <location>
            <begin position="95"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="PtIM" evidence="7">
        <location>
            <begin position="242"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="356"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="555" mass="62050" checksum="7D6161970E0D7AE9" modified="2016-11-30" version="1">MAQYIFSMNRVGKIVPPKKFILKDISLSFFPGAKIGVLGLNGSGKSTLLRIMAGVDKEIEGEAIPMKGINIGYLAQEPQLDPTKDVRGNVEEGLGEIQQIVKRYNAVNDAFAEPDADFDALLAEQAELQEKIEAANAWELERELEVAADALRLPPWDADVAKLSGGEKRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERFLHDYPGTVVAVTHDRYFLDNVAGWILELDRGQGIPWEGNYSSWLEQKQNRLAQEEKQESSRQKAMQAELEWVRSNTKGRHAKSKARLARFDEMSSQEAQKRNETQEIFIPPGPRLGDVVIDVEHVNKGFGERLLVNDLSFKLPPGGIVGIIGPNGAGKTTLFRMMSGVEQADSGEIKLGSTVQLSHVDQSRDDLDDNKTVWEEISDGLDLITVGTYETPSRSYCGRFNFKGGDQQKRIGDLSGGERNRVHLAKLLRSGGNVLLLDEPTNDLDVETLRALEEALLAFPGCAVVISHDRWFLDRIATHMLAFEGDSQVVWFEGNYEDYEKDRHKRLGTDADNPTRIKYKKITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLK0</accession>
    <name>A0A1D3RLK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_12008_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000116">
        <property type="protein sequence ID" value="SCN46543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015223">
        <property type="entry name" value="MipZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09140">
        <property type="entry name" value="MipZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="219" mass="23938" checksum="B9EA9A911B34002E" modified="2016-11-30" version="1">MIISFLGQKGGTGKSSVARAVAVEFVRSGWSVHVADMDTIQKTVFNWAGRRADAEIEPALEVALYREPKAALKAADISDLLIIDGKAFADAHLLTVAKASDLIIIPVGVNADDLEPTLNLATELINKGISRASMLFVVDKVPDNGEREAMETRQTIKNWAFNVSQGYIPFKTAYSQAMDAGRTLNETKYKGLNEKTDKIIQQIVDAAINTQDKKSKRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLL7</accession>
    <name>A0A1D3RLL7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chaperone protein HtpG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Heat shock protein HtpG</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">High temperature protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">htpG</name>
        <name evidence="7" type="ORF">BAZMOX_03267_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Molecular chaperone. Has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000128">
        <property type="protein sequence ID" value="SCN46556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HATPase_c" evidence="6">
        <location>
            <begin position="30"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="A; substrate-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="C" evidence="5">
        <location>
            <begin position="567"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="646" mass="73166" checksum="E2D2AD93D9B197F9" modified="2016-11-30" version="1">MTVEAKKETLGFQTEVKHLLQLMIHSLYSNKEIFLRELISNASDAADKLRFEALSNDGLYEGDSELKIKISFDKDAQTITVSDNGIGMTREEVQEHIGTIAKSGTKQFFESLTGDQAKDSELIGQFGVGFYSSFIVADKVTLITRKAGSEEATLWESTGEGEYTLETVEKVGRGTDIILHLKESEKEFLDHYRLSSIVKKFSDHISLPIVMDKEIPAVTDEEGNETEPAKVEEETINSASALWTKSKDELDEEAYNEFYKHVAHDFQDPLAYVHSKVEGTNEYTMLLYVPARAPFDMWDRDAKHGVKLYVRKVFIMDDAEQLMPRYLRFIRGVIDTDSLPLNVSREILQQSKKINTIKAGAVKKVLGLLEGLAKNDKEKYATFWEQFGNVIKEGPIEDHKNKERVAKLLRFASTHTDTDTDTDVQDVSFEDYISRMQEGQDKIYYVTADSFAAAKNSPHLEIFRKKGIEVLLLSDRIDEWLVSNLNDFDGKVLQSVAKGQLDLDKLDTEEDKKEQEETSKDFESVITQIKEVLKDKVSDVRLSHRLTASPSCLVTEQDAMSLNMERIMKEAGQDMSMMGMGGSKPIFEINPEHALVTRLKEEQDDERFSDLTRILFDQAVLSEGGQLDDPAEFVHNLNGLLQGLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLM8</accession>
    <name>A0A1D3RLM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_63318_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000023">
        <property type="protein sequence ID" value="SCN46418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4600" checksum="456FFE46CE572261" modified="2016-11-30" version="1">MYDNRIIHYFTEISQFLFKETLDNANIFRKLALSNVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN2</accession>
    <name>A0A1D3RLN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03205_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000127">
        <property type="protein sequence ID" value="SCN46554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="269" mass="31377" checksum="A2E06F1D32BE20E6" modified="2016-11-30" version="1">MEEFKKIDFENADMTGKLMAETRDRQNAYLVNVENFQASRRVFSVQARMLVDSLAKERIDEVIRRTKDDMSKSLTTYGMKQNIRKLFDELRDLLQDAVDTTNETRRLVKAIHKKFRDEYGFKEIEPKLFSIKQYQFELEQIFEEGELFRSSARTTMTEQSVVVKKLYSTIISKAREVLKRANKDATTWSNSVLSPLMHQIKDHKKQIESRLQMLRKISGSKESIEENIANLAAELGPLKQQHRELKMIIKAMKVDNITEYKDASAAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP3</accession>
    <name>A0A1D3RLP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_498076_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000154">
        <property type="protein sequence ID" value="SCN46582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4196" checksum="C3CB68445E8FE0B1" modified="2016-11-30" version="1">MCTMALVDFSKTISLPLYGLKDGEYKYIVNDEFSGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP9</accession>
    <name>A0A1D3RLP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminodeoxychorismate synthase</fullName>
            <ecNumber evidence="1">2.6.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_01476_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.6.1.85" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000038">
        <property type="protein sequence ID" value="SCN46438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005802">
        <property type="entry name" value="ADC_synth_comp_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00553">
        <property type="entry name" value="pabB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="4">
        <location>
            <begin position="17"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="3">
        <location>
            <begin position="189"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="456" mass="50828" checksum="1FA6A0EFC4670A25" modified="2016-11-30" version="1">MPSTPQLYSLPYLLDSARLFSAIAAQPWSIFLDSGLAEKRQGRYDIFATDPLCTLITHGAETQVCPGNNTYVSKQDPFTLVKQQLTAQKAFPEVPFNGGAIGYFAYDLGRQLEKIPKLTVDAEHIPDMAVGVYQWAVVVDHQEQKSYLVGCADSDQQWQALIKQFSAYPEAVTVGEFQVTSSVQANMSEESYAQAFAKIKKYLQEGDCYQVNLAQRFVANCQGDPWAAYQQLRKINSAPFSGYLNVPGVQVLSSSPERFLKVFQGRVETKPIKGTRPRKENEQENQQQIDALQNSHKDRAENVMIVDLLRNDISKNCIPSSVKVPKLFEVESYATVHHLVSTVTGRLDEKYHALDLLRSCFPGGSITGAPKIRAMEVIEELEPNRRGVYCGAIAYIGFDGNMDSNIAIRTLVHSEHTIRFWAGGGIVNDSVLEEEYQECFDKAAAMLSLLAQMQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ9</accession>
    <name>A0A1D3RLQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_06966_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000090">
        <property type="protein sequence ID" value="SCN46509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="174" mass="19197" checksum="7B7AA399239CC740" modified="2016-11-30" version="1">MDYYAPSENEIASFLGINQAHIDTKKYAARLVSCDVPYLIVPVYYYETVRNATFNFAAWSQSIAPQTAAQEILIVSPKTPYQDSDFAARLVGPNIGAHEDPPVGSAIPALAAYLCSFEHMQKGTYTFAVQRGDDKMRRSILNLEMDHKGEDTLNLRVGGEAVMVAEGTIFIPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLS6</accession>
    <name>A0A1D3RLS6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="13">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">carB</name>
        <name evidence="17" type="ORF">BAZMOX_00985_2</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="13"/>
    <dbReference type="EMBL" id="FMJP01000183">
        <property type="protein sequence ID" value="SCN46631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_A">
        <property type="entry name" value="CPSase_L_chain_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="133"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="678"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="16">
        <location>
            <begin position="936"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="13">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Oligomerization domain" evidence="13">
        <location>
            <begin position="404"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="13">
        <location>
            <begin position="936"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="828"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="840"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="842"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SCN46631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="1072" mass="117741" checksum="3377045F9FF530DA" modified="2016-11-30" version="1">MPKRTDIKSILLLGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPDMADAIYIEPIDWQTVEKIIEKERPDAVLPTMGGQTALNCALDLDEHGILEKYGVEMIGATKEAINMAEDRQLFNDAMARLGFEVAKSKTAHSMEEAFAAQVEVGYPTVVRPSFTMGGSGGGIAYNKEEFIDICERGLYLSPTNELLIEESVLGWKEYEMEVVRDTKDNCIIICSIENFDPMGVHTGDSITVAPAQTLTDKEYQILRNVSLAVLREIGVDTGGSNVQVAINPADGRMVVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELQNEITGGATPASFEPTIDYVVTKVPRFTFEKFPQADDRLTTQMKSVGEVMAIGRTFQESLQKALRGLEVGVDGLDEIIDFTESGAEEKMQREMRHPGPDRLWYVADAFRSGMAFDDVHEASKIDPWFLAQIEDLVLTEKSLVTKTLATLEEGQLFRLKQKGFSDARLAKLLGTKERDVRKLRHKQAIRPVYKRIDSCAAEFSSDTAYLYSTYERECEARVSDKEKIIILGGGPNRIGQGIEFDYCCVHAALALREAGYETIMVNCNPETVSTDFDTSDRLYFESLTFEDVMEIIDLENPKGVIVQYGGQTPLKLARDLEAAGAPIIGTSPDAIDLAEDRERFQQLIEKLNLKQPPNGTTSSTEQALSAAKELGFPLVVRPSYVLGGRGMEIVYNEESLQRYMKEAISVSNESPVLLDRFLDDAIEMDVDAIYDGETLLIGGLMQHVEQAGVHSGDSACSLPPYDLPVHFQDQLRVQVKQMAEALGVRGLMNTQFAIQGENIYVLEVNPRASRTAPFVSKATGYPLAKIAALCMAGISLKEQGITEERIPNYFSVKEAVFPFVKFPSVDPLLGPEMKSTGEVMGVGKTFGEAFAKSQRAAGVDLSHSGKVLISIREADKPKVVEVAKMLIAKNYQIVATRGTAKVIQAAGIECEKVCKVNEGRPNTVDMIKNDQIQLIINTTEGIKAISDSFTMRREALQHRVTYYTTMAGAKAACYALGELGAGDVNCLQELHRTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU2</accession>
    <name>A0A1D3RLU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Delta 1-pyrroline-5-carboxylate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01476_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000038">
        <property type="protein sequence ID" value="SCN46437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="194" mass="21250" checksum="F01B43EC3AA7041A" modified="2016-11-30" version="1">MIVLKLGGSLLSSSILPQWLHLAVKEGKGRLVIVPGGGVFADQVRSTQKKWQYDDQTAHYMAILAMQQMALLFKGLCPDLCIVNQVAAIRPALDKQALVVWSPLATELDSGKIKASWEVTSDTLAAWLATQLSADQLMLVKSAQLPENATLQQLSEHNIVDQAFADFVQYNPIRLDCVSLTQTYALSASLKKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU7</accession>
    <name>A0A1D3RLU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative RNA-binding protein containing KH domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_00985_4</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000183">
        <property type="protein sequence ID" value="SCN46633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001890">
        <property type="entry name" value="RNA-binding_CRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035920">
        <property type="entry name" value="YhbY-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01985">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01103">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75471">
        <property type="entry name" value="SSF75471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51295">
        <property type="entry name" value="CRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="93" mass="10792" checksum="C3DA649991F0CA49" modified="2016-11-30" version="1">MIGKAHPYSLYYDRSSGFNDPVLNEIELALNNHELIKIKVRAERDTRKLIQEAIIAATNAELIQSIGQIIVIYRKKPEVEPKKKKQGSRRRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLV4</accession>
    <name>A0A1D3RLV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">guaA</name>
        <name evidence="12" type="ORF">BAZMOX_04566_3</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000071">
        <property type="protein sequence ID" value="SCN46488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="212"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="239"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN46488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="529" mass="58454" checksum="F577310B1173501B" modified="2016-11-30" version="1">MNQHSTTDIHAHKILILDFGSQYTQLIARRIREIGVYCEIYACDCSDDEVRNFGAKGIILSGGPESVTLGNTPRAPQAVFDAGVPVLGICYGMQTMTEQLHGKVESSDHREFGYAQVRARGHSKLLKDIEDAVTVEGFGLLDVWMSHGDRVVELPEGFKLIASSDGAPIAGIANEEKDFYGIQFHPEVTHTKQGGRILRRFVLDICACDALWDSAHIIDENIQIIKEKVGTDQVVLGLSGGVDSSVVAALLHKAIGKQLTCVFVDTGLLRLNEGDQVMAMFAENMGVNVLRINAEQRYLDALAGNSDPEQKRKIIGNLFIEIFDEEAAKLTDAKWLAQGTIYPDVIESAGAANGKAHLIKSHHNVGGLPENMQLKLLEPLRELFKDEVRQLGLELGLPANMIHRHPFPGPGLGVRILGEVKKEYADLLRKADAIFIEELYKNNLYHTVSQAFAVFLPIKSVGVMGDGRRYDYVIAIRAVETVDFMTARWAHLPYDFLGLISNRIINEVEGISRVTYDISGKPPATIEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW1</accession>
    <name>A0A1D3RLW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00299_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000198">
        <property type="protein sequence ID" value="SCN46652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="6"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="349" mass="40126" checksum="583A85EADE6EA0E6" modified="2016-11-30" version="1">MPQQVDYLIIGQGLAGSLLSWELLQHGCSIHLIDNQQENASQIAAGLINPVTGMRLVKNNHIDTLLPCAKKIYQTLSQFFQTDFYIEKSMLRIIRNEKENLSYQKRCHDPSYLDYLEPHLAQAPRSIHAPLGLIQQKQTGYLLTHKLLSHLKNYFQALQCYQACQFDYQNLQLNDTITWQGISAQKIIFCEGYQAINNPWFSYLPFQLAKGEILTMRTEQRLIPQMLNYGHWFIPLDAHQFRTGASFEHNHLDTKTTLKAQAQILATLSQTYPALSSASVEKQQANIRPTTRDKAPFIGLHPKHQNLAIFNGFGAKGSLQIPYYSQHFVQHLLNQTPLEERVNCLRYDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLW6</accession>
    <name>A0A1D3RLW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_210005_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000222">
        <property type="protein sequence ID" value="SCN46695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="58" mass="6561" checksum="E557D35AF13A962A" modified="2016-11-30" version="1">MIIKAAAAIFIDIGLIEFSAFLLTNKTPEHRFAVVLDIGDNLWGAYRITLPKVKFIFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX3</accession>
    <name>A0A1D3RLX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA methyltransferase, TrmH family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_11390_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000203">
        <property type="protein sequence ID" value="SCN46666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="172" mass="19101" checksum="61FAA14E8F8DAB66" modified="2016-11-30" version="1">MKKSKVSIGLVNPKSPDNVGSVMRAAGNYRVDRVFFTGERYLRALEFQVQAVNTGRQVGRGIPISKADCLLNEAPENMKIVCIEFAENAISLPKYQHPEQALYIFGSEDGTISQDIIDKADAVVYVPTVGCMNLAATVNVVLYDRMAKSTQRIESNELIRASRDRNNTLKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM12</accession>
    <name>A0A1D3RM12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FIG065221: Holliday junction DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_07693_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000171">
        <property type="protein sequence ID" value="SCN46609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MgsA_C" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="164" mass="18337" checksum="3DC4DE5777AA1928" modified="2016-11-30" version="1">MIDGGCDPLYLARRIVRIASEDIGNADPRALQLCMNAWETQERLGSPEGELALAQALVYMSCAPKSNAVYRAFNAAMSAAKQSGSLPVPKHLRNAPTKLMKSLDYGKEYRYAHNEPEAYAAGESYFPEQLMETQYYQPVTRGLEIKIAEKLKHLRELDRIAGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM15</accession>
    <name>A0A1D3RM15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_210005_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000222">
        <property type="protein sequence ID" value="SCN46694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="67" mass="7175" checksum="1C789A65010A708D" modified="2016-11-30" version="1">MGLNLPIGLPAGKTNPVEIIHLAKPGLSIESVLKGCANKSSKPPVINKRPGTTLQWKINFTLGKVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM16</accession>
    <name>A0A1D3RM16_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Methenyltetrahydromethanopterin cyclohydrolase</fullName>
            <ecNumber evidence="6 12">3.5.4.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Methenyl-H4MPT cyclohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">mch</name>
        <name evidence="14" type="ORF">BAZMOX_06146_0</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O = H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin</text>
            <dbReference type="Rhea" id="RHEA:19053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58018"/>
            <dbReference type="ChEBI" id="CHEBI:58337"/>
            <dbReference type="EC" id="3.5.4.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (H(4)MPT route): step 3/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the MCH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.27" evidence="6 12"/>
    <dbReference type="EMBL" id="FMJP01000227">
        <property type="protein sequence ID" value="SCN46703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00562">
        <property type="reaction ID" value="UER00703"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018759">
        <property type="term" value="F:methenyltetrahydromethanopterin cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00545">
        <property type="entry name" value="MCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00486">
        <property type="entry name" value="McH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003209">
        <property type="entry name" value="METHMP_CycHdrlase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02289">
        <property type="entry name" value="MCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03120">
        <property type="entry name" value="one_C_mch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="13">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SCN46703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="327" mass="35072" checksum="72EFCC93ECDAD6C1" modified="2016-11-30" version="1">MEYTASVNKLTQPLVQELLDNADKLRLKVQKLDNGCTIIDAGIEVPGGLEAGRIITEICLGGMGTVSLSHSAYTENWPLTVNVHTSNPVLACLGSQYAGWSLSHEKYFALGSGPARAMATKEKDGQIVPVEELYKELDYNDKAETATLVIENDAIPPIEIVQKIAKACNVDLEKLTIIVTPTSSLAGGVQVVGRVLEVAMHKAHELHFPLENIIDGMGSAPLCPPHPDFVQAMGRTNDAILFAGLVHIFVKGSDAEAEKLAMALPSSTSKDYGKPFAQVFKDAKYDFFKIDGMLFSPASVIVTAVEAGNSFRAGKLDNALLNQSFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM36</accession>
    <name>A0A1D3RM36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonuclease E</fullName>
            <ecNumber evidence="7">3.1.26.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_11087_3</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.1.26.12" evidence="7"/>
    <dbReference type="EMBL" id="FMJP01000268">
        <property type="protein sequence ID" value="SCN46765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="39"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="292" mass="33246" checksum="4A93C51547678602" modified="2016-11-30" version="1">MKRMLINATQPEELRVALVDGQKLYDFDIEHPSQEQKKSNIYKGIITRIEPSLEAAFVNYGADKHGFLPLKEVSPNAVNSDDPNLSRQKIKDLLKESQEVIVQIEKEERGNKGAALTTYISLAGTYLVLMPNNPKAGGISRRIEGETRNELRDAMAGLEVPENMGLIVRTAGCGKSTDELQWDLNYLLQLWEAIDRTSKEKNKPFLIFQESNVIIRALRDHLRADIDEILIDKESSFKLVHNFLKQVMPHYLNKAKLYSDDVPLFNRYQIESQIETAYSRSVPLPSGRGARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM43</accession>
    <name>A0A1D3RM43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_14658_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000244">
        <property type="protein sequence ID" value="SCN46724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4840" checksum="BA46BD2927F4E877" modified="2016-11-30" version="1">MSPFQYLRQIDETFKHKKEGQKSVKYWITTPQYPPKSDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM68</accession>
    <name>A0A1D3RM68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Probable ATP /GTP binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00671_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000273">
        <property type="protein sequence ID" value="SCN46770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021228">
        <property type="entry name" value="BrxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10923">
        <property type="entry name" value="DUF2791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="441" mass="49451" checksum="696343DC161D55C3" modified="2016-11-30" version="1">MGKRIRLKERDAIIQSLKSGVTPKIGIQHIQVGRSNEVKALYNDIERISQGGAAFRLIIGDYGSGKTFFLSVVRSIALEKKLVTVNADLSPDRRVHASSGQARNLYSELMRNLATRNKPDGNALASVVELFVTQARKEADEKNSDVSTVIHQKLTSLSELVGGYDFAKVIDAYWNGHEQDNEELKSNAIRWLRAEYTTKTDARRDLDVRTIISDNSFYDALKLMSLFVRQAGYEGLLVNLDEMVNLYKLSSTQARTSNYEQILRILNDCLQGSAEYLGFLLGGTPEFLLDPRRGLYSYEALQSRLAENSFAQRAGVIDYSSPALHLASLTPEELYILLKNLRHVFAEGDTSKYLVPDDALKSFLHHCSQTIGDAYFRTPRNTIKAFLDMLAVLEQNPSIQWSQLVQSIVIEKDRPSDTDEIIVGEETGEILDSDGLADFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM98</accession>
    <name>A0A1D3RM98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_01705_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family. DsbE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000295">
        <property type="protein sequence ID" value="SCN46800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03010">
        <property type="entry name" value="TlpA_like_DsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004799">
        <property type="entry name" value="Periplasmic_diS_OxRdtase_DsbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00385">
        <property type="entry name" value="dsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="34"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="177" mass="20057" checksum="1ABAEFD7E0E5A938" modified="2016-11-30" version="1">MPRLLLFIPLALFIALSFFLWKGLSIDPRKLPSALIDKPFPEFQVEALLQPERMLSKADFVGKPVLINVWATWCPSCRQEHEQLLRIAQDNKIDIIGLNYKDERAAATNWLRQLGNPYVFNIYDEAGMLGLDLGVYGAPETYLLDAQGVVRHRHVGVVTAQTWVELQAMIQALGVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA5</accession>
    <name>A0A1D3RMA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_26729_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000310">
        <property type="protein sequence ID" value="SCN46821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="214" mass="23905" checksum="103D16679059273E" modified="2016-11-30" version="1">MKGIAIVGTKGGVGKTSIAHLLALGAAWKNTPAYLMHTDDREPIAVNGRPYMYYDARKPEILSTLMGAAINNDGFCIVDSGGNRPKFDKWIAESVDIVLMPVIPDPEGVEMAVKHMQQLEEYGAKNVRFIMNMVSSNENEHFRDFREYFSKLPEGKIIGKIKKVAAVKRLRESDIEPFKTPPSNVNNLSRTLYFTVKAALESIDKDEKKEKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD4</accession>
    <name>A0A1D3RMD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_290678_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000236">
        <property type="protein sequence ID" value="SCN46719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037048">
        <property type="entry name" value="KorB_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="49" mass="5648" checksum="44B04306765FA4A0" modified="2016-11-30" version="1">MLLIEYEGEPGRLIFKNTLEYGKVIIKTRQGETKEVHASQIKVLSIEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMF6</accession>
    <name>A0A1D3RMF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hopanoid-associated RND transporter, HpnN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_01616_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000313">
        <property type="protein sequence ID" value="SCN46826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017841">
        <property type="entry name" value="Hopanoid_biosynth_HpnN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03480">
        <property type="entry name" value="HpnN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="721"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="774"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="816"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="844"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="7">
        <location>
            <begin position="301"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="871" mass="95375" checksum="B285AA393A9782B3" modified="2016-11-30" version="1">MNPNMSRSTKILEWLGHFIVRYAWLLVISTLLLSSLSLYYVKDHLGVNNNSAEMLSPDLPFQKDTKRFDTAFPQNADTIIFIVEAATPEETAIASKQLLNSLKNSSHYFESSYIPEDNAFFRQQALLYLSPEELEKLASNLTDAQPFIGYLTQNYSLTGLFTILTQALEQQDSVISQSLPALLNSINQAIINTIRNQSYHVSWQTILNPSKLANKTRRIVIAKPKRDFHSMMPAAAAVKKAREITPQLSANMANLKIGITGDVVLQHEELESIGDGAVLSGIGSFILVFLILFRCFHSFKLLFATIITLLIGLSLTAGFAAIAIGHLNVISISFAALYIGLGVDFAIHVCLHYREGIAQKHSHFIAIKKALHSVGFSLFLCALTTSIAFFAFVPTDYKGVSELGLISGVSMFISLGLSLVFLPALLSLLNLKKAHAFENSNQTSWIKTVPLRYKKTIRSISILLAIACLFAIPYITFDSNPVDMRNPNSPSVIAFKNLLKSTTDSPYALNALCKNIEETHSLVQKLKQLPTVSNTVTLTDLVPSDQEDKLFTIEDLNMILGPQLSQFDSTLAPSDTPKVLSEFQNTLSSVLKNNQSGISAEILQALSHSIGQYQAALQQSTDPAQLNKRLDDSILGLLPHTISTLSQSLTAYEFNLDSLPDYIRNQWLSPTGIYRVMILPKQDLNIPANLKQFALDVQSVAPAAVGLPVGDLASGQAVVNAFKMAFSFSFALITILLLLILKSLYKTLLVLGPLILASLLICSVNVLLGIPFNFANIIALPLLLGMGVDSGIHIMHCLHEQLEDNQHILQSSTARGVMFSSITTMSSFISLALIPHFGIASMGITLAVGISFTLICTLIVLPAFSNKTITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMG6</accession>
    <name>A0A1D3RMG6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_00523_7</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="652" mass="75334" checksum="9CEF375D74FB5B13" modified="2016-11-30" version="1">MQQMQLFDPEEDAQNLDNWFQDAIKFFNLDEEPRWPDHFGTAFHNWHMNQKNTKIKTLSLFSGGGGLDIAFHDMGFDIFECVEIEKKFSDSLLLNSAKGKRLYGCNVVCKDIRDYAPTEQDIDFIIGGPPCQTFSAAGARASGVNGMDDRRGTLFQEYVRILNQVRPKAFLFENVYRIVGAQGGEPWLLIQEAFKGAGYKLHWRILDAADYGVPQHRERLIIVGIRGDCDFLFPSPTHGPDSTNKKAYYTAGNAVIGIDTNKCKTGINGRHGHLLNDIPPGLNYSFYTEKMGHPRPVFGWRSKFSDYLYKADPNTPTRTIKAQGGQYTGPLSWENRHFMLDEFKRLQTFPDDYEISGNRQTAIHQIGNSVPPQMGRIMALAIMNQVFELELPFNIKYLKHDEKLGFRVRKSSLTAIYKNKAAEYINLKFPDNKADTYKKESGSCNMELTDKFQLVEHNQSNSTTFSLNFTIDYNKWVFKCENKTNSDHKIFSILIKMSPEQKNIINIGEVHLISYDKRPTSVLVLWKFFEKKLNNLAHKDDLIQIFGYYQYKQSFNFDFKLTKEDMEPWFFWKVISHITRGECVGKTLNINDIADYYNIHTAHLLEALKMLKTIGFEIRSCNTNKQIKEGDYLIPYQFPTLNERSLQRLTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMG8</accession>
    <name>A0A1D3RMG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OmpA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_11843_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000353">
        <property type="protein sequence ID" value="SCN46895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="78"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN46895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="193" mass="22139" checksum="C275FC3F0DB2213C" modified="2016-11-30" version="1">MQEALIKKIVKYMQVMKDTKLVIVSDTQSIGRADDRLFKSRAKKIVDLLVKQGLKKSRIAVQSKLSMIDLENNDKILRIHVFGPDVLKMFWFNKGSLHLTAKEKHRLDLVARYMQHQTKALIINSHTDGMGRKAHNMVVAQKRGEVVKRYLESQGVSADKLTVRAYGEKKPIASNRTRKGQAKNRRVELSFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML3</accession>
    <name>A0A1D3RML3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrogen peroxide-inducible genes activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_131620_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000356">
        <property type="protein sequence ID" value="SCN46903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysR_substrate" evidence="1">
        <location>
            <begin position="2"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="203" mass="22935" checksum="19920A74478A5F01" modified="2016-11-30" version="1">MIPTVAPYILPKLLPVLNQRYPEAQLDIVESQSDILVDRVRQGDLDTAILALPFPCDGLLTLKFWQEDFYWITLKGNQYSQQQEVTSDELKNCNLLLLKEGHCLKDQVLSACNRTEQTAQQHFSATSLNTLIQMVLGDLGTTLIPEMAIEQLTSQHKTLSVVHLNEPGPHRQLAFILRPNFTRLSSIEALISICKDAFSQYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN5</accession>
    <name>A0A1D3RMN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent Clp protease adapter protein ClpS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">clpS</name>
        <name evidence="3" type="ORF">BAZMOX_05055_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to the N-terminal domain of the chaperone ClpA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpS family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000270">
        <property type="protein sequence ID" value="SCN46768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00302">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="PTHR33473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpS" evidence="2">
        <location>
            <begin position="24"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="107" mass="12010" checksum="66299F9105483A3F" modified="2016-11-30" version="1">MSDFDPSIDNDDALAVQEAAPKLKRPPLYKVVLLNDDFTPMDFVIEVLVDFFAMSEEQATQVMLHVHTQGVGICGVFSRDVAETKVELVNTYSREHQHPLLCAMEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP5</accession>
    <name>A0A1D3RMP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_05516_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000279">
        <property type="protein sequence ID" value="SCN46778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="58" mass="6520" checksum="72A9227D96D0F9E1" modified="2016-11-30" version="1">MGQIAYDDIPIAGYDAKLCIVGVLKVAFDKEMLPAPLRPIAYFDSEWDLSAAERLWCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMR2</accession>
    <name>A0A1D3RMR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alkaline serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_60068_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000407">
        <property type="protein sequence ID" value="SCN46962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="58"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="336" mass="35909" checksum="AD3A0314DF6C3912" modified="2016-11-30" version="1">MLMTPDVMEKPLIEKGEEENGKEETRTLITQKNAGWGLARLHQGTATSDNSYQYKYDGSGRTIYVLDSGLNINNPKVAAEFGSRASILSDVNFAGKGEDCTGHGTMVSSAAAGKTYGVAKGATLKMVKITEGCHIYTFDSSSVTAINWITKNAPKGSIIVRSYGIRDRGPGIPIPCKRTRSAPALEVAIKKAHDAGMFVVLSAGNDACDTKNYSPKNIPESFVVGSTSNLDFIHGKDRIASFSRKGTNISAFVPGTNLLLMKEDGEPISKSGTSFSAPYVAGTIAVVCQAVEPLCESKDMAYLYDAFRDTGTLNTVTNTDGTPLTGATSRFISQQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN02</accession>
    <name>A0A1D3RN02_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04389_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000477">
        <property type="protein sequence ID" value="SCN47052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4275" checksum="5A43DE9C8486BC0A" modified="2016-11-30" version="1">MAMVLVLTPKRRAKSILLVLAQRIIALECELVFAFMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN10</accession>
    <name>A0A1D3RN10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplS</name>
        <name evidence="7" type="ORF">BAZMOX_00434_4</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="115" mass="12982" checksum="BE899D9FA15B237C" modified="2016-11-30" version="1">MSNIISQLEAEQLNQNIPEFNPGDTVVVQVKVKEGERERLQAFEGVVIAKRNRGLNSAFTVRKISHGVGVERVFQTHSPLVGDIQVKRRGAVRRAKLYYLRELSGRAARIKEKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN22</accession>
    <name>A0A1D3RN22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulatory protein zraR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_01797_1</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000517">
        <property type="protein sequence ID" value="SCN47105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="298" mass="33156" checksum="CCF4B93088B680DF" modified="2016-11-30" version="1">MIAATDVSVLIKGETGTGKEVLANAIQKDSHRADKPFITLNCAALPESLIESELFGHRKGSFTGAITNKTGLFQAADGGTLFLDEINSLPLSIQAKLLRFLENGECLAVGDVSTYKVDVRIISATNADLQKQIAMGEFREDLYFRLNVIPLEIPPLKKRVEDIEHLIKHFQDHFSKIHDRAAPKFSKQALKILQNHKWPGNIRELRNLCERTSILLSGQTIDAENFPHDFFAVKTSLDPSNTDFSLPEAGISLDKLEADLIHQALERTNGNRAKSARLLGLSRDTLLYRIQKHGIANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN43</accession>
    <name>A0A1D3RN43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03276_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000342">
        <property type="protein sequence ID" value="SCN46877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920239" evidence="1">
        <location>
            <begin position="20"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="210" mass="23228" checksum="159DC3C76D98A2A5" modified="2016-11-30" version="1">MKKLIFVVFLLLFTQSAFSGAMDERVSEIEGSWADTREIEAVPERKNIFLQLVNDITEVITEFPSQAEPLILKSAILLTMAEDASSFVALGLVKEAKSLLQKAIGINPAASKGSALVTLGVLYYKVPSWPIAFGDNDEAEAYLLKALEVDPEGIGSNYYYGEFLLEQGKKEQAVSFLNKALNIRVNPKDRKSKIRIKEQEKARVALANLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN87</accession>
    <name>A0A1D3RN87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sigma-54 dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_315040_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000377">
        <property type="protein sequence ID" value="SCN46927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="1">
        <location>
            <begin position="95"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="187" mass="20298" checksum="109399AEB35FF21D" modified="2016-11-30" version="1">MTSSVFGGIAARNFGYAKVEIAKSIAQHDGCCEVYIHLNPEIAKNKQGIEYRDNRNDNKHDQNVDALHSRIEESMLKIWRKQSQKLAKRCLPPLIIADSTGMKKVLQSIEVIAPTTATLLIQGQTGVGKELVARAIHAMSDRCNKVFVPINCGAIAESLLESALFGHEKGAFTGAIAENQGNGAIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN92</accession>
    <name>A0A1D3RN92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DsbD_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01797_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000517">
        <property type="protein sequence ID" value="SCN47106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039447">
        <property type="entry name" value="UreH-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13386">
        <property type="entry name" value="DsbD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="199" mass="21465" checksum="6DF864A5EE328400" modified="2016-11-30" version="1">MCGSIIGTLSFSLKPEIRSNKTKMATFIFSYNLGRIFSYMLAGLIIGLIESIITMPLGEEHGHQILKIISALIITGAGFYIAGWFPSFAYIEKTGSRFWKTIEPYGRKLIPVATLKQAFLFGMVWGWIPCGLVYTALALAATSGDIVTSALSMLAFGLGTLPAVMGVGLVSSFISRISSLRTTKQVIGMLLVLVAIISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA0</accession>
    <name>A0A1D3RNA0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rep_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_206652_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000547">
        <property type="protein sequence ID" value="SCN47143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000525">
        <property type="entry name" value="Initiator_Rep_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01051">
        <property type="entry name" value="Rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rep_3" evidence="1">
        <location>
            <begin position="66"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="263" mass="30883" checksum="65C7E732481EA748" modified="2016-11-30" version="1">MSNDMMEVVARTKRFINRDFSLGEYDRGWTKLERYLFIEVYEVIKDFYIATSDKNIISYSSDLMRLKIPTSNLNPKFFSRKNMGRDLYDAAKRLSKKQINTVSVGEGGQVGFSFKNIFSEIVYAPENDKENIYVEITSQIYEEMVPIESYCILDLKLISDFNSGNTVRLYEIFKSYAFRKKITLSFTSLRKKLGFFEEGSYEEWKHFNAQVLKPAVKEINNKDDKNKELFRDIEVFYEKKRGSQDINFTIVKVDPIVKTISSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNA6</accession>
    <name>A0A1D3RNA6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YjeF N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_36377_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000577">
        <property type="protein sequence ID" value="SCN47195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="1">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="7709" checksum="6F915B0733A9AF87" modified="2016-11-30" version="1">MQTLPIKLYSAQQAREIDRIAQEQTQVTGLQLMAKAAEASFQVIKKHYPEAKKSLFFVVLAIMLEMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND5</accession>
    <name>A0A1D3RND5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01012_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000580">
        <property type="protein sequence ID" value="SCN47200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008309">
        <property type="entry name" value="UCP025560"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07027">
        <property type="entry name" value="DUF1318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920264" evidence="1">
        <location>
            <begin position="29"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="197" mass="21825" checksum="4F3B3B4AEA20A720" modified="2016-11-30" version="1">MSIKNLSMFGALLLTACVTINIYFPAAAAEKAADEIIQDIQTLEPSQPQSEMSPQSALPKWQVSVYQLVDQTISVFISSAHAEANLSVNSPEIRRITADMRARFGALIPFYEQGVLAIRADGLLTTKGSVPLKDRNKLSKLIAAENADRYKLYQAIANANGHPEWAAQIKSTFAQRWISHAQSGWWYQTANGSWKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RND8</accession>
    <name>A0A1D3RND8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03040_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000555">
        <property type="protein sequence ID" value="SCN47156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TonB_dep_Rec" evidence="1">
        <location>
            <begin position="2"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="70" mass="7934" checksum="7D9CFE6427514A22" modified="2016-11-30" version="1">MVNLQTEYRFNKHVKIFARLDNVFDEKYNNFGMYGETGDVLENLGIGEQSTRFVGVSAPRAGWGGIKLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE7</accession>
    <name>A0A1D3RNE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_218857_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000576">
        <property type="protein sequence ID" value="SCN47193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021558">
        <property type="entry name" value="MazE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11455">
        <property type="entry name" value="DUF3018"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="8223" checksum="A22008F0D061D6F6" modified="2016-11-30" version="1">MLVTERVKKHRDKLRENGYRPIQIWVPDVRIPEFIAEFRKQSQQLKDDPQEKEILDWVGNTADSSEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNG8</accession>
    <name>A0A1D3RNG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type I restriction-modification system, restriction subunit R</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_87924_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000436">
        <property type="protein sequence ID" value="SCN47007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="488" mass="55889" checksum="6BC9E8880AA82DC8" modified="2016-11-30" version="1">MVDRKDLDRQTREEFNKFQEGCVEENTNTETLVRRMLSEDYADKVIVTTIQKLGLALDETSKRNQANKQKGKKTYKERLEPLRNQRIVFIFDECHRSQFGDNHQAIKAFFPNAQLFGFTGTPIFEDNASYKQIDGTQASYKTTEDIFQKQLHAYTITHAIEDRNVLRFHIDYFGEQPKGAEGKKGKKPKPKLPAPEAVVNEIVNKHDAATNQRRFNAVLATASINNAIEYYELFKQVQEKKLAEDDSYKPLNIACVFSPPPKALAKDSEKINEKNVADIKQLQEDLPQEKADNEEAPEEKKKALKTIIADYNSQYDTNHGINEFDLYYQDVQQRIKDQKYSNKDYAHKNKIDIVIVVDMLLTGFDSKYLNTLYVDKNLKHHGLIQAFSRTNRVLNDTKPHGMILDFRYQEQAVNEAIAMFSGANKDKAKEIWLVDPAPEVIKQLDSAVSKLEKFMHSQGLACTPEAVNNLKGDAARAELLITLKKCNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNH9</accession>
    <name>A0A1D3RNH9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tpiA</name>
        <name evidence="5" type="ORF">BAZMOX_04671_3</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="FMJP01000446">
        <property type="protein sequence ID" value="SCN47017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="250" mass="27253" checksum="0459F05658FBFACD" modified="2016-11-30" version="1">MRRGLVIGNWKMNINWHSAIALVDGIVADMPAVNADLVVCPPYLYIPEVSARITDTRLICGSQNIAAHAEGAYTGEISGSMLREFDCKYAIVGHSEHRKYYADDNVVVAKRYRQAIASGIVPILSTGDSLAQRKQGTTFEVVAKQIEDVIDIAGIDSFHHAVISYEPLWAIGTGRTATGEQAQEVLEFIRRLIDSKSPEIAEKIQILYGGSVKPENAKNLLAMPDIDGVLVGGASLDADSFLKIYSSFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ2</accession>
    <name>A0A1D3RNJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00619_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000609">
        <property type="protein sequence ID" value="SCN47242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="106" mass="11868" checksum="F99BEE1DFB79F664" modified="2016-11-30" version="1">MFDHLFATEINNTPDVIYVPRESAQFESNSNAAKNQHTSTNTNTALKTEPFILKNFNNQGYDLKVYANNCDSEFADLLAKQVSGFYISPNKTTTTKQNSSGLGFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ5</accession>
    <name>A0A1D3RNJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02905_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000594">
        <property type="protein sequence ID" value="SCN47224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="42" mass="4574" checksum="E7DDEBB4D382A48F" modified="2016-11-30" version="1">MGAILDVTEMLKEPAGMAVAAVVIAVGYFFVKWVFAEPEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL1</accession>
    <name>A0A1D3RNL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_65702_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000651">
        <property type="protein sequence ID" value="SCN47305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="345" mass="40982" checksum="3926D74A3C626325" modified="2016-11-30" version="1">MSNGYDFLADRIKDCKSNNTIHRQRKSEFFSTNRTRFVNYRHKLKRLTHSGKHAEFRRMVQKIQNSWREAEETRFKNLSEDDRQDLADHYFFALDAECEYKRLIFDKNFVNSEIFQTIRDLTKYTSEANIPNMLCSARYGSAIFMADESSFEEGLSYIQEAKQKFDLVHSCLETGIVLYIEYNMEYNNWHTKFSHKMEPDKKKYFLSLGYRAVDHFQQEGETNPEVSEDFTRMFRLKLSHLYLGIGLFGDYLNTEVTHQDVNESKYLLKAIEDNNDMWNRMETRWKCFYYIAKARISYLDGNLCEALDNTGHALDLAIEGNYTNEIRCTRENIKNIENIITSQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL5</accession>
    <name>A0A1D3RNL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_70712_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000478">
        <property type="protein sequence ID" value="SCN47057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="347" mass="40357" checksum="8D7219E9F3B4A683" modified="2016-11-30" version="1">MKIGRNDPCPCGSGKKYKYCCLSASPAVSDELTELLSDQEFDSIEELQAVTDTLVAKQNHKPHDDFLGLSSEQVFRMLNFAFDTPELFQFSEQLLIEPSAPILMLIEGIISAIDETGLQATKANGNLPQKLCRDVWSDYNKLYVDPDFSGVHKVNKEDDFFELHVARITLELAGFLRKTKGRFFVTKKYQKIDNNFGVKGIYPIIFKTYCREFNWGYWDRYSDTPFIQQSFLFALYLLKQHGEKMTFTSVYEDDFLRAFPMVLDEMEEVSYFSSEESFRHCYCSRVCQRFLVFLGLAELEVIKGDKDYTKKYKIKRTPLFDAVVHFNFLDPKNYKTMHSNIHKGNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNM9</accession>
    <name>A0A1D3RNM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_66689_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000618">
        <property type="protein sequence ID" value="SCN47254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007215">
        <property type="entry name" value="Sulphur_relay_TusB/DsrH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04077">
        <property type="entry name" value="DsrH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="97" mass="11004" checksum="51EA8DA79D789A3D" modified="2016-11-30" version="1">MLHIIDNFPLQHSFLESTHSGDTVILKDNAVYAVKQENIKESLTEKTFAHLNLCVSKADLLLRNISNNELLRGVAILDNMNDFQDTLIDDIACRSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN0</accession>
    <name>A0A1D3RNN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glutamate 5-kinase / RNA-binding C-terminal domain PUA</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_04234_4</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000632">
        <property type="protein sequence ID" value="SCN47282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006561">
        <property type="term" value="P:proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="10"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="220" mass="23577" checksum="8CE26E6CBF9313B4" modified="2016-11-30" version="1">MSRSEFATAKRVVIKIGSALLTDGGKGLNQAAIAVWVEQMALLKQQGIEVVLVSSGSVAEGMARLGLKTRPKVLHELQAAASVGQMGLVQAFESNFQLHDQHTAQVLLTHDDLSDRRRYLNARSTLLTLLSYDVVPVVNENDAVATEEIRFGDNDTLGALVANLVEADLLIILTDQLGLFDSDPSVNPNAQFISEVSADDSRLATMAGGSRSGLVVAVWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNQ4</accession>
    <name>A0A1D3RNQ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Flavocytochrome MsrQ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">msrQ</name>
        <name evidence="9" type="ORF">BAZMOX_00840_4</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="7">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="7">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MsrQ family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000567">
        <property type="protein sequence ID" value="SCN47179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01207">
        <property type="entry name" value="MsrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022837">
        <property type="entry name" value="MsrQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36964">
        <property type="entry name" value="PTHR36964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="8">
        <location>
            <begin position="48"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="198" mass="22806" checksum="61B2D457B3D82533" modified="2016-11-30" version="1">MRLSRPHWVVIKISIFLLSLTPFLLLVKDTLQEQLGANPIETLHFTLGDWALRFLCITLALTPLRKLLQQSWPIRFRRMMGLFAYFYASLHFLVYILLDLSLSWTHFIDEVPQSPYILAGLLTFLLLTPLALSSSKAIQKSLGKRWGQLHKLVYIAGISAVIHYLWLVKSDISEPLFYAAVMSILLGTRLILYFKKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT0</accession>
    <name>A0A1D3RNT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_129335_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000641">
        <property type="protein sequence ID" value="SCN47296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4543" checksum="77D9B7F522A57C5E" modified="2016-11-30" version="1">MTNLSTGGEAFNWYLKRFRIETLFSDLKGRGFNLGSVASTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT8</accession>
    <name>A0A1D3RNT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoxR-like ATPase in aerotolerance operon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_04812_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000707">
        <property type="protein sequence ID" value="SCN47385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="43"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="256"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="328" mass="36473" checksum="114D5610C282CD01" modified="2016-11-30" version="1">MSDVSTSDSLIAIQQLKSTISKQIIGQDVLVERMLIALLADGHILVEGAPGLAKTRAINALSKGIQADFHRVQFTPDLLPADLTGTEIYRPEQGSFEFQKGPLFHNLVLADEINRSPAKVQAALLEAMAERQITVGGETYKLPQLFLVMATQNPIEQEGTYPLPEAQLDRFLLHVKIDYPAPEHEKHILHLARNEAIQNGKPEQKPTLGISQESLFNARQEVLNIFMADNLEDYLLQIILASRNPAAYGEDLTNWIQYGASPRASIALDRCARAKAWLNGKEYVGPEDIQELAFDVLRHRIILSYEAEAEGITSDYFIAQLIARIAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNV7</accession>
    <name>A0A1D3RNV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-damage-inducible protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_18693_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000724">
        <property type="protein sequence ID" value="SCN47405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003497">
        <property type="entry name" value="BRO_N_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02498">
        <property type="entry name" value="Bro-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bro-N" evidence="1">
        <location>
            <begin position="21"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="137" mass="15391" checksum="3489094D9B6FFBA5" modified="2016-11-30" version="1">MKNDLTQQMTESFEGHAQETENGIEYWLARDVQHLLGYTKWDDFLNVISKAKTACELSEHSIPDHFADVGKMVELGSGSQREISDIMLTRYACYLIAQNGDPAKQAIAFALQTRKAELIEKRLTLVPTLLRGNAYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX6</accession>
    <name>A0A1D3RNX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cobalt-zinc-cadmium resistance protein CzcA Cation efflux system protein CusA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_86743_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000608">
        <property type="protein sequence ID" value="SCN47239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="237" mass="26624" checksum="0C2648B36F3723BE" modified="2016-11-30" version="1">MINQIINLSLRNRLLMLVLAVVVIATGYRSYQGLPVDAFPDVSPNLVQIFTITEGLAPEEIEMYVTYPVEAAMTGLPAVEKIRSVSNFGLSVVNVYFEDDVSIYFARQLVGERLQEARNQIPSSFGEPSMGPISTGMGLVLFYYLKDDTHKYSLEDLRTMQDWIVKFNLQTVRGVTEVLGIGGFEKQFHVIVQPDALLRYKVTLNELIERVRANNLNVGAQYLLNSYNKCITSESNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNZ4</accession>
    <name>A0A1D3RNZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04184_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000731">
        <property type="protein sequence ID" value="SCN47410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="86" mass="8878" checksum="22BBB2D78785B924" modified="2016-11-30" version="1">MTCSVRACWELSAGKGVDFDRGKSMLMSVLGRAGVVFLVVSIALLGATVFCVVVDKIGADLGVIKFCVFSGSIVFCVAVALVDGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP08</accession>
    <name>A0A1D3RP08_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04812_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000707">
        <property type="protein sequence ID" value="SCN47384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="48"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="292" mass="33737" checksum="03438942FFEF4450" modified="2016-11-30" version="1">MSETNELTSVNLKMLINLVKPAATLQLFRSRIRALQSGGHVSRIKGRGMEFDEVRPYQPGDDIRSIDWRVTARTGKAHTKLFREERERPVFISVDYRASMQFATRGVFKSVQAAKLASLIAWVAQHHSDRIGGQIFTDFFCKELKPQHGKQAVLHFLNTLTQPQPKQKTLNFEQIMRRLSQHVKPGSLVYIISDFRGLNKATEQYLAKLARHCEVIMILIYDPLESHLPSNGRYRFTDNNKDIVVDTSDKQRVLSYQDKFQQHCITLQQLANKLNIRYLRCASNDDPIQILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP11</accession>
    <name>A0A1D3RP11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_269846_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000748">
        <property type="protein sequence ID" value="SCN47430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4850" checksum="EB7516E1D6702238" modified="2016-11-30" version="1">MRPAEKNFHFLHGFNHTIFKDLTEQILYPKCSKMHHFASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP20</accession>
    <name>A0A1D3RP20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_86743_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000608">
        <property type="protein sequence ID" value="SCN47238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="9"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="207" mass="23038" checksum="9F8DC9ECEE6A638C" modified="2016-11-30" version="1">MQSKDKDLTLYELRAPAEGVIIEKHAVRGEVLATNTRSFTLADLSQVWVNLTVYQKDLARIQRGQSVLISNRFDSSEQNVATQGVISWISPTLDEQTRSAIVRVVIDNPEGHWRPGMFVSAKVAIEQAEAEIVIPLSALQTMDGQTVVFVQHDDGDFEPQSVQTGRRDFKQVEIIQGLKVGQSYVSQNAFSLKAQMQKGEFGEGHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP30</accession>
    <name>A0A1D3RP30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase and inactivated derivatives</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_18693_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000724">
        <property type="protein sequence ID" value="SCN47404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="10"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="176" mass="21090" checksum="82BFB562E4F1C037" modified="2016-11-30" version="1">MGRSRYKITNPEMLHFITLTVLHWIPVFTRQETVNILLESIKFLAKDGLKVYAYVILENHCHFVIQSKQLDRDIAHYKSYTAKQMIQYLSNNNVKQILEQLAFYKKAHKNDRAYQFWQEGVHPELIQNDEMMRQKINYIHLNPVKRGYVDQAEHWRYSSARDYLGQLGLLEVCTQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP59</accession>
    <name>A0A1D3RP59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00594_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000802">
        <property type="protein sequence ID" value="SCN47525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018741">
        <property type="entry name" value="DUF2288"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10052">
        <property type="entry name" value="DUF2288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="97" mass="11138" checksum="D66BEA8E1CEAD708" modified="2016-11-30" version="1">MNQEDLTKEKVNQETSKIAWSELQRFFASGLAVYVAAELDLVEVADAFSKDNKIKVEQWMQTQQVNLVSDQQATDWISNDTMMWATVVKPWVLVQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP63</accession>
    <name>A0A1D3RP63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase IS2020, hypothetical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_25926_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000788">
        <property type="protein sequence ID" value="SCN47490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="134" mass="14702" checksum="BC2C06C6A42BFFB9" modified="2016-11-30" version="1">MLSERRDEDAATTFFKQAINNNGFPDKVVMDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIIEQDPRFIKKITKPMMGFKAFHSAQATIAGIEAAHMIRKGQRGVAIFAKACFGHPSPSKRQKLNATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP78</accession>
    <name>A0A1D3RP78_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rhodopirellula transposase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_253185_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000815">
        <property type="protein sequence ID" value="SCN47545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011518">
        <property type="entry name" value="Transposase_36"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07592">
        <property type="entry name" value="DDE_Tnp_ISAZ013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="128" mass="14704" checksum="F7EFBFA083D7F688" modified="2016-11-30" version="1">MLMDGGGSNSSRHYIFKQDLQVLADEIGVNIRVAHYPPYTSKWNPVEHKAFPHITRAMQGVVLTSHQLTKELIETATTKTGLKVFASILNRVYETGRKVAEGFKESMRIVFDEHLRRWNYVAVPEKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP80</accession>
    <name>A0A1D3RP80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_381064_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000653">
        <property type="protein sequence ID" value="SCN47308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032874">
        <property type="entry name" value="DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13610">
        <property type="entry name" value="DDE_Tnp_IS240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_Tnp_IS240" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="125" mass="13916" checksum="BC1A8C9835A16EC1" modified="2016-11-30" version="1">MLSERRDEDAATAFFKQAINNNGFPDKVVMDKSGANYAGLANINLLLILAGFATMIDICQVKYLNNIIEQDHRFIKKITKPMMGFKAFHSAQATISGIETAHMIRKGQLSEENMPAYKQFMALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH1</accession>
    <name>A0A1D3RPH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lipid A export ATP-binding/permease protein MsbA</fullName>
            <ecNumber evidence="12">3.6.3.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_02898_2</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.6.3.25" evidence="12"/>
    <dbReference type="EMBL" id="FMJP01000884">
        <property type="protein sequence ID" value="SCN47635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034040">
        <property type="term" value="F:ATPase-coupled lipid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011917">
        <property type="entry name" value="ABC_transpr_lipidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02203">
        <property type="entry name" value="MsbA_lipidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="46"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="357"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="391"/>
            <end position="398"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="602" mass="66446" checksum="FA57FEBD91596A1F" modified="2016-11-30" version="1">MEFLVRAKLMCTRLSLSFFCMTQKTSSFTIYTRLLKYVVPFIKFFIVSVLGFVIVAVAQPLFAELVKLIINTIEQGNKAENKFLPAYIMALVLLRSTGAFFGNYFLAKVSVNVVNQLRQEIFNHYTKLSIEYFDAQNSGHLISLITYNVAEVTRAVTDSVRTFIREGLTAIGLLGYLLWLNWQLTLIFFIIAPFIAVLVTKVSKKLRSLSTNVQDSMGDMTHITSELVMGARVVKCFGGSDYEIKRFKKVSLFNKQQSQKVALVAAIQNPIMQLLVASALSALLFLALTIMDTASTGDFVAYLLAAFMIPKPVQSLAQANNDIQKGIAAAGDIFNALDVEPEKDQGTIDKTKGKGVLHFENISFSYPNSKQLALKKINLTIEAGQTVAIVGASGSGKTTLTNLIPRFYDYTQGRILIDGIEINQYSLSCLREQIALVTQNITLFNDTVFNNIAYGVLGNVEEAAVLKAAEDAYATEFIEALSHGIQTEIGEHGIQLSGGQRQRLAIARALLKNAPILILDEATSALDTQSERYIQKALEHVMAHRTTIVIAHRLSTIEKADVILVMEHGEIIERGSHTELIAKQGAYAQLHAMQFTESAGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPH6</accession>
    <name>A0A1D3RPH6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ORF">BAZMOX_04315_2</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000822">
        <property type="protein sequence ID" value="SCN47554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="206" mass="22103" checksum="E5A6A0592E793A98" modified="2016-11-30" version="1">MSLKVPALNSADSAGEVEVSEGVFGKDYNEALIHQLVVKTMAGQRSGTKAQKNRADVSGGGAKPWKQKGAGRARSGTIRSPLWKGGGATFAARPRSFDQKLNKKMYRAGIRSILSELLRSNRLLVSSDIIPTTPKTKELAAKLKDFGSSRVLIVADELDENIYLSSRNIARLEVTTANELDAVMLIAAENVIATPAALKAIEAQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK5</accession>
    <name>A0A1D3RPK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_09834_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000773">
        <property type="protein sequence ID" value="SCN47469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="72" mass="8015" checksum="582A9597B3D76A3E" modified="2016-11-30" version="1">MTNKTKAERIAEQVAQAVNAGKELHLESVDFSDPDRPKTCLEVDFPILPINQIAQIEGNAGKPTLKIRETER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPL9</accession>
    <name>A0A1D3RPL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_47653_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000709">
        <property type="protein sequence ID" value="SCN47387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="120" mass="13951" checksum="81D1310D7488C366" modified="2016-11-30" version="1">MLILDDSSAKDKILHHYKQTNEKVQSSIIAFQFYDRMQQCLQHVTENLTGLSDIVDSPQLLYNPIEWGKLQDKIRKGYTMESEKVMFDAILQGKTIEHAMQLAAEHVNSNEYDDDDIELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP0</accession>
    <name>A0A1D3RPP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_319675_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000912">
        <property type="protein sequence ID" value="SCN47670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="118" mass="14770" checksum="7AB4EC66A1AEBCE3" modified="2016-11-30" version="1">MLLIYLDGFRYSESLYEIDLRERTIRVEEELKHQRELMQEGFKQMEKRFEQVDKRFEQVEKRFEQIDKRFEQVDKRFEQMSLESDKRFTEMNRRLDRFMFWSLGITVSCALFVVTYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPT7</accession>
    <name>A0A1D3RPT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coagulation factor VII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_84921_0</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000941">
        <property type="protein sequence ID" value="SCN47713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920263" evidence="1">
        <location>
            <begin position="24"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="22"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="267"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="351" mass="39071" checksum="98708ABD26BC9CE9" modified="2016-11-30" version="1">MKPNSFIKLFFFTILIYTNLTLASSENTDDVTSSSNSWPSMVTIYHSTGSDWNFQCGASLIDKNWVLTAASCMKGVSAAKELLVIIDEESANVYRGISEIIIHAEYSRHDNDYAMLKIQEVPSWVKPIKVKPIQLPPPYPMEDWHLGTSSAKGLSWDVTENKVRELDLTRISNSLCSKNEKMSGRYGKDWITDNMICAGQGLGKKGTCDGVSGGPLTVFRGHTNTWMHLGVSSFGGGCAPYGVYARTSKITRWVSDLMCSNEEVPDIPSSLKFHINDDNTVTVKWASVSGVTGYNLNYRLKGESFKHSMDLKENDFTTSTDVSGNSYYVTVNSYKNNCLSKETKEKYITLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU1</accession>
    <name>A0A1D3RPU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stringent starvation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_32578_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000937">
        <property type="protein sequence ID" value="SCN47711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007481">
        <property type="entry name" value="SspB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036760">
        <property type="entry name" value="SspB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37486">
        <property type="entry name" value="PTHR37486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04386">
        <property type="entry name" value="SspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005276">
        <property type="entry name" value="SspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101738">
        <property type="entry name" value="SSF101738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="124" mass="13959" checksum="B66ED82E5D0A64B8" modified="2016-11-30" version="1">MTSLKPYLLRSIYEWIIDNNLTPHLLVDASHPHAVLPEDYIDEGKIVLNIRPEAIQSLSLGNTTVEFNTRFNGQSMHIIAPVPAVLAIYAKENGKGMVFDPEEDDNEPPPENKPPQRSHLHVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU6</accession>
    <name>A0A1D3RPU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_05068_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000978">
        <property type="protein sequence ID" value="SCN47765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5378" checksum="CA158BCE34FD825A" modified="2016-11-30" version="1">MVAGYYAHKHRKDIIGSVNSATGKGKDFVLQQKENLEDLVAESKEDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPU9</accession>
    <name>A0A1D3RPU9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_47804_3</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000986">
        <property type="protein sequence ID" value="SCN47775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="170" mass="19306" checksum="EABEAFD4ABFC951C" modified="2016-11-30" version="1">MDVTAIIDSLNDAQRQAVSAPSRSMLVLAGAGSGKTRVLVHRIAWLIQVEHISPHNILAVTFTNKAAKEMRGRVEELLNISARAMWIGTFHGLAHRFLRQHSEEAKLPSTFQVIDSDDQLRLIKRLMKAMNIDDTRWPPKQMVWFINAQKDEGIRASHIQETGDLYQQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX6</accession>
    <name>A0A1D3RPX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00666_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000962">
        <property type="protein sequence ID" value="SCN47750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="570" mass="62846" checksum="DEEFF19F983542CF" modified="2016-11-30" version="1">MKFERHIVGGLLLSVSFQAQTLWAVEFNAAQGAAIAIESELTKDKLIENAVEVINANDPSIKVIDAMEVAPAPAYQPIDAEDQLNQYLATKGLHSGWIEEKKMYISTGVAFFDSEDPSYDDSFITKRSMKSMEAKLNAKADIIEFINTTMSALDKVEVTGTDIYAKFNERQIKNQKKLAAQQRAVAVLLADVDAKQADELRGVTFSDRAKAYMDAAIKKLDETYSVEKIEEKKRVKFQKAKERYLAAKKEQEVLEKEISAFQGQTRGKSSSQIATLSSMPLFGAVTVNQFESWDADSEQYKVALLVMWSKSTEKMARAMITGEKIVIPPGPVTLQTWLNNQNWATMTGSRRFRDERGDGWFIGVDARPIGSSSSSERQARGLAEMSAKKEVAMSLFADMESKKRAETVMIERTDAQRQDASQALGSYAASLRSSIKNRSISGLQKLYAKKVTHPISGQKIYIAVYGMSSSTARKALAMQGSNYVTQLLDIKSQQKLKGTKAGLKAAVHAAEQEQSAYRAAKQNAKQQVQTEAARMTVNSTTSRQTHKSAAPQSKGSQSGVYGGGADSFDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ13</accession>
    <name>A0A1D3RQ13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MutL_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_113537_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000992">
        <property type="protein sequence ID" value="SCN47781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4964" checksum="E538C36EC8F2B6A5" modified="2016-11-30" version="1">MTYERFKTQYHQGSVPSQPLLLPVQVQVNSAEADLADDQQAVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ30</accession>
    <name>A0A1D3RQ30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_62777_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000946">
        <property type="protein sequence ID" value="SCN47722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="295" mass="34468" checksum="AF98CE2C7B4B48B2" modified="2016-11-30" version="1">MRGEWIKVINCRHFKRIKQPLIATLLGMVVTFQYACAADRGIIHRAKEVKQQMRTTAYDDYLHQAELRSEVKIWPASYQIVSRLNARYNSADAIVHGAQARMNRIHLACWYFCHATDEFLDAEIAERRWLELRDHISARLSLIKSENKDEGTTAAVEFERAQKQWYLSVPQKAKAFNINEYVVRHFKTTTYDEDARLTLVAEEAEMAWALNVFLEMRKYIAHISDSEARKRLNAKYKEADEYLAGRVAYYNTLVEAETDEAEATEEVNMLKAKELLQYWVNIQQLHKLITTGELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ33</accession>
    <name>A0A1D3RQ33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="8">KARI</shortName>
            <ecNumber evidence="8">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="8">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ilvC</name>
        <name evidence="12" type="ORF">BAZMOX_117158_0</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000902">
        <property type="protein sequence ID" value="SCN47659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014359">
        <property type="entry name" value="KARI_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000116">
        <property type="entry name" value="IlvC_gammaproteo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8 9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="8 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="10">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="11">
        <location>
            <begin position="182"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="24"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="338" mass="36538" checksum="434897FD8D7D692E" modified="2016-11-30" version="1">MQVYYDKDADLNVIKGKKVAIIGYGSQGHAHANNLQDSGVDVIVGLRANSSSVAKAEAHGLKVTDVAAAVASADVVMILTPDEFQSQLYKEEIEPNIKQGAALAFAHGFAILYNQVVPRADLDVIMIAPKAPGHTVRSEFVRGGGVPDLIAIHQDASGTAKEICLSYASAIGGGRSGIIETTFRAETETDLFGEQAVLCGGAVELVKMGFETLVEAGYEPEMAYFECLHELKLIVDLMFEGGIANMNYSISNNAEYGEYVTGPKIINEESRYAMREALASIQNGEYAKKFILEGMTNYPEMTAKRRLNAEHPIEVTGAKLRAMMPWIAANQIVDKAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ41</accession>
    <name>A0A1D3RQ41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_80079_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000949">
        <property type="protein sequence ID" value="SCN47732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="382" mass="44237" checksum="0A5687F5B14A4CBB" modified="2016-11-30" version="1">MARADNGKWIQDIRDEISEFEVIKNDNIDAYNHYKTWDYAVMAAELAEKRYASSLKKSIEAQNRIYDRNWLYDLDYFVRKYSNQALLDIFSCKNKAWREKNLTKIEAGMERTPTEELDRSKRRLTAVENAISCYVDMYTNLSSRKQAYHGSRADDLMATDELYALRKYDLPQAKMALKYITEFIAAIEPYIPHAVYEVFPGWVNHDSMGYRYTQDCDDSQIRKVFIVLDGISGLSYWSGIQDLTSGDMAWPLQKVVNSCGMVILPLNTLSVGVSRIWGFSLQKTLESEVDQVKEIIDTIDPAMRIFLMRGTDDGRTAEAVLDSLKVGRNHRRVAGLVTVDKNTERIAITYNKDWFAGSEEERMALKIKESMIFYDILRLVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ45</accession>
    <name>A0A1D3RQ45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Possible conjugal transfer protein TrbJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02191_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000875">
        <property type="protein sequence ID" value="SCN47618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="264" mass="28676" checksum="50B87DFF754ECD20" modified="2016-11-30" version="1">MVATSVVSLIPFSQVNATGIPVVDIAHIGIQTGFWTADSAEQAAQTAEQVITSAENVLQTIESVTQTAQQIQMVANWVKNLDRLGASEWVGLINDNVIQSSEITNVMNSVAALQYDAARIRSQMNAIFPQGGDWSTYNFSNLRNARQTWNSTLTDAVNGAMQAQAAINKIAARNNRIQTLLNDSNGADGTVRQIQVGNQLNAALIASVNDMNQSMIATQRMFAIKHQMEISEREAGQEQYVRFMSSYTSRGAAVTVPSSLPPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ84</accession>
    <name>A0A1D3RQ84_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartokinase</fullName>
            <ecNumber evidence="5">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_129026_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000853">
        <property type="protein sequence ID" value="SCN47597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="165"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="245"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="312" mass="33871" checksum="EE11AF75CDE448EE" modified="2016-11-30" version="1">MRIETDSAHTKARIKRIDDARIHADLAAGKVVVVAGFQGMDEQGNITTLGRGGSDTTAVALAAALKANECHIYTDVDGVYTTDPRIEPKASRLDKITFEEMLEMASLGTKILQIRSVEFAGKYNVALRVLSSFAEGRGTLITYEESEVEQALISGIAFNKDEAKLTITGVPDIPGAAFKILGPIADANIEIDMIIQNVADDATTDFTFTVHRNDFVKAQEILTNICNNLEARAVTADDSIVKVSIVGVGMRSHAGIASKMFEVLGQEAINIRMISTSEIKISVVIDEKYLELAVRTLHKAFDLDKEPKEVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQA5</accession>
    <name>A0A1D3RQA5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable oxaloacetate decarboxylase gamma chain</fullName>
            <ecNumber evidence="10">7.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">oadG</name>
        <name evidence="12" type="ORF">BAZMOX_08831_0</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 10 11">Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:57724"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="EC" id="7.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10 11">
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Heterotrimer of an alpha, a beta and a gamma subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10 11">Cell membrane</location>
            <topology evidence="10 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10 11">Belongs to the OadG family.</text>
    </comment>
    <dbReference type="EC" id="7.2.4.2" evidence="10"/>
    <dbReference type="EMBL" id="FMJP01001024">
        <property type="protein sequence ID" value="SCN47834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015451">
        <property type="term" value="F:decarboxylation-driven active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00404">
        <property type="entry name" value="OadG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005899">
        <property type="entry name" value="Na_pump_deCOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023424">
        <property type="entry name" value="OadG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04277">
        <property type="entry name" value="OAD_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01195">
        <property type="entry name" value="oadG_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0915">Sodium</keyword>
    <keyword evidence="10 11" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10 11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN47834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="75" mass="8054" checksum="DF3CC8EF2B03FAE6" modified="2016-11-30" version="1">MNETMTQGVELMFTGMGIVFLFLVMLIGAVKLMASCVTRFFPEEVQPAQVAPRAASQSTAVTAAITAAVHQHRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD3</accession>
    <name>A0A1D3RQD3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_29456_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000970">
        <property type="protein sequence ID" value="SCN47759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="185" mass="20507" checksum="0E1DFA780E1FB50A" modified="2016-11-30" version="1">MIAINLAAAAVQMGLKPLVICQDPQGTSSMIYEGGRLPFEVISNIPKDKPDANLVLIDHQASDWQLPQGRLLLMPVKPARTQYKTYVDAQKIAEKAGKQIITIVTDAQHHRTEERETAKRLVEKGALEIPSSGVFSRADAQLLTIFDEEMNKAYKIKDRRNDFLKILGAVLADALEQEGEKKNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE6</accession>
    <name>A0A1D3RQE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome partition protein smc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_384980_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001029">
        <property type="protein sequence ID" value="SCN47842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="89" mass="9722" checksum="7EE567AE9DC9CAE1" modified="2016-11-30" version="1">MALVFSIFDLNPAPFCLLDEVDAPLDEANVRRFSAMVEEMSANVQFLYISHNKVTMEIAGQLAGVTMKEPGVSRMVAVDIQEAVAMAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQF5</accession>
    <name>A0A1D3RQF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_117266_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001035">
        <property type="protein sequence ID" value="SCN47852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="3929" checksum="CEF2F0A09B4DDCD3" modified="2016-11-30" version="1">MGTTAFAGGGVSVRGCFSFDCKLDLYVLDGNLTGQKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQG1</accession>
    <name>A0A1D3RQG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Amylopullulanase</fullName>
            <ecNumber evidence="1">3.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_12951_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.2.1.1" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01001066">
        <property type="protein sequence ID" value="SCN47886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="99" mass="10980" checksum="D19BF571819FDA81" modified="2016-11-30" version="1">MLGDAKWAFDKVRATGRLSKMQVMEAEFQLAVCEGSDWFWWFGDYNPGQAVSSFEKQFRLNLANLYSILGEEVPAYLALSFTQGSGAPAMGGTMRKGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQG3</accession>
    <name>A0A1D3RQG3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_445571_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001042">
        <property type="protein sequence ID" value="SCN47862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="63" mass="7065" checksum="2E0B20402B9117AF" modified="2016-11-30" version="1">MITDLQANSPAAQVGLMKGDIILAVNKRKVRTLKDLNKAASLSRKKLLIHLQRGQSFLYFVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQH3</accession>
    <name>A0A1D3RQH3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YciL protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_07964_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000929">
        <property type="protein sequence ID" value="SCN47697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="100" mass="10828" checksum="1831B1FB6778842A" modified="2016-11-30" version="1">MLYAILSVDVADSLEKRMAARPAHLERLQILQDEARLIIAGPHPAIDSNDPGKAGFTGSLVIAAFDCLTDAQSWANSDPYLIAGVYTSVTVKPFKQVFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQH7</accession>
    <name>A0A1D3RQH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_00676_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="51" mass="5613" checksum="8DC7F27012BD216A" modified="2016-11-30" version="1">MKNLDVMIKGPGPGRESAVRSFNNLGFKIGNIVDVTPIPHNGCRPPKKRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQI0</accession>
    <name>A0A1D3RQI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase sigma factor RpoH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_35365_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001079">
        <property type="protein sequence ID" value="SCN47906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="169" mass="19335" checksum="5E2F24849CE26B25" modified="2016-11-30" version="1">MAMSAKIGTSKFFGVTMSNSLALPITLTAGNFDSYLNVVGQTNKLNAEEERELAIRFRDHQDLEAAKQLVMANLRFVAHVARGYNGYGLPMNDIVQEGNIGLMKAVKRFNPNLGIRLVSFAVHWIRAEIHEYVIKNWRIVKIATTKSQRKLFFNLRKSKKNFRLDFLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQI5</accession>
    <name>A0A1D3RQI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_25418_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001015">
        <property type="protein sequence ID" value="SCN47819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920285" evidence="1">
        <location>
            <begin position="22"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="261" mass="30641" checksum="492D5DB194D613AE" modified="2016-11-30" version="1">MKILMLLSVVALLSTVTSVNASQASLREARAKYQQMKIDATARYKRMKDKRAESVVWSAPQETVDRLQAWYYRLDEVRYKAQLKFERYGFSLSFIRTDSYADSKDAERVWLQLMNRVIPEQAIAKAEVKPQGTTADVELDRAKRYLAWALNERDMGVRFNNFIHRSLRTRIFHWDATEVERHARLEWLWAVEQYGTQKALVNSQSETRALEQLKVDNEVAEAYLAKQESDEEFRLSEISGFEAVQLEMVRQSLKRFWRISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQJ0</accession>
    <name>A0A1D3RQJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_29456_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000970">
        <property type="protein sequence ID" value="SCN47758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="95" mass="10783" checksum="8A9E73E3A4F62F31" modified="2016-11-30" version="1">MPRNDTSWMDEEDERAESQADTGQPPNAEAPQLVRKEAKAPPRATKGFYIQELHSMAFDRLVFEQKQAKGKKAPELAEEAIELLLKKYGLNINNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQK0</accession>
    <name>A0A1D3RQK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11064_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000947">
        <property type="protein sequence ID" value="SCN47727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920274" evidence="1">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="10290" checksum="81F94D9A05DA4917" modified="2016-11-30" version="1">MHNFTKTLAAMTLLAPMSAHSLGVGTIKLHSALNQKLNAEIMLSLSAGEELADIKVSLASPDKFDQAGIAWNSFLAKIKLEPILKANGQVVLKYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQP5</accession>
    <name>A0A1D3RQP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmJ</name>
        <name evidence="6" type="ORF">BAZMOX_00676_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="PTHR42888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4280" checksum="48A9F195DC164B61" modified="2016-11-30" version="1">MKVRASVKKICRNCKVIKRSGVIRVICKDGRHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL77</accession>
    <name>A0A1D3RL77_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_37 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_56150_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000024">
        <property type="protein sequence ID" value="SCN46422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039554">
        <property type="entry name" value="HigA2-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13744">
        <property type="entry name" value="HTH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_37" evidence="1">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="76" mass="8927" checksum="6931120CDBA48A52" modified="2016-11-30" version="1">MKYDNLELRKELISAIVEQIKIKELKQHDAAILLKIRQPKVCLLMNKKIENFRLEKLIELAGRVDLQVDLDIKLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL78</accession>
    <name>A0A1D3RL78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="13" type="ORF">BAZMOX_01179_1</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000036">
        <property type="protein sequence ID" value="SCN46431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="14"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="659"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="871"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="867"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="539"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN46431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="936" mass="106968" checksum="EB1A486194258197" modified="2016-11-30" version="1">MDKTYTPTDTEQRWYNTWEEKGYFSAKQEGESFCIMIPPPNVTGSLHMGHAFQDTIMDALTRYHRMKGESTLWQPGTDHAGIATQMVVERLINKEGKTRHDYGREEFIKRIWEWKEESGGTITKQLRRMGASLDWERERFTMDDGLSDAVKEVFVTLHEEGLIYRGKRLVNWDPVLHTAVSDLEVLSEEENGFMWHMHYPLANGEGHLIVATTRPETMLGDAAVAIHPADERYQHLLGQFIKLPLSGRLIPIIADEYVDPEFGTGCVKITPAHDFNDYDVWSRHKEMSAIQDQAHGGLINLFTMDAVIRANEAEEGDLIPAAYIGLDRVAARKQIVADLEVLGLLEKTEDHKLMVPRGDRSGSIIEPLLTDQWYVKVAPLAEPAIEAVKSGEIQFVPDNWKNTYYDWMNNIQDWCISRQIWWGHRIPAWYDEQDNIYVGRSEAEVREKHNLAADYPLRQDEDVLDTWFSSALWPFSTLGWPEKTPELAQHYPTSVLVTGFDIIFFWVARMIMMGQKFMGEVPFKKVYIHGLVRDAQGQKMSKSKGNVLDPIDLIDGISLEDLVAKRTGGMMQPHLAEKIEKATRKEFPEGIPSYGTDALRFTFASLASTGRDIRLDSDRLYGYRNFCNKLWNAARFVLMNTEEQDCGINGGELKYSEADKWIVSRLNQVIANTTDAIDNYRFDHAAQEIYEFTWNEYCDWYLELSKISLQSDNEALQRGTRQTLLTVLETILRLAHPVMPFITEEIWQRVAPLAGVQAETIMLQPYPVADDTQIDAQAVDAIEWTKQFILGVRRIRGEMNIAPGKPLPVLLENVTETDENHLAQATTYLQKLGRIESIKCLAENDIAPESAISLVNELRILIPMAGLIDKEAEIARLEKEILKLEKNLPRIEGKLNNPKFVDKAPDEVINKEKEKLAALHTSLTNFNEQLVKIRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL87</accession>
    <name>A0A1D3RL87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01179_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000036">
        <property type="protein sequence ID" value="SCN46432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="144"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="262" mass="29249" checksum="D233F1A2710DBA4E" modified="2016-11-30" version="1">MTTQYANLHVILVEPSTTQQHIIRNYLTQAGINDIICCNSGAELFTSLSRTQPDLIISAMYLPDMTGSELLYTLREDEEYDKAFMLISSETNLSSLEPIRQTGAIAILPKPFTAEELQIALSATVDYLNPEKAILNHFDIEDIAVLLVDDSPLALKYISNILNDIGIEKITQVNDGSKAIPLLQECYFDLIITDYNMPDIDGLQLTSFIREQSEQKTIPIIMITSEQDSQRLAAIQHAGVSAILDKPFEPASIRNFIINLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL93</accession>
    <name>A0A1D3RL93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SoxZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_93501_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000040">
        <property type="protein sequence ID" value="SCN46443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014880">
        <property type="entry name" value="SoxZ_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08770">
        <property type="entry name" value="SoxZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SoxZ" evidence="1">
        <location>
            <begin position="2"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="4810" checksum="65DA6102BA21B63D" modified="2016-11-30" version="1">MGYGISKNPFFSFKIKSAKAGDKVSISWQDNLAYSDTQEHIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RL99</accession>
    <name>A0A1D3RL99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_339772_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000051">
        <property type="protein sequence ID" value="SCN46451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4328" checksum="F359916825BCBB87" modified="2016-11-30" version="1">MARLNPCAIDEILTERVQFRTRDGGFDTFVDVIKIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLA1</accession>
    <name>A0A1D3RLA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_15316_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000053">
        <property type="protein sequence ID" value="SCN46453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="6975" checksum="79B26980E1DCD5A3" modified="2016-11-30" version="1">MRAYDPDNCAFCRLMRSLAFTGVGMGIGSGTAYLLGATQENIMMSGIVVSAIIVFGLLDKNKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLA7</accession>
    <name>A0A1D3RLA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_268034_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000076">
        <property type="protein sequence ID" value="SCN46495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="144" mass="16559" checksum="3C655E9616C8775D" modified="2016-11-30" version="1">MIEKFIGLWVDNNANLLLIEPWKLNILNSGIVKVLFASGKTKAPVSRDFMQQQFTVDVPGEFHNGHEELIIQFGKAYYGPQLHLKYEITDNYKGKASLDPSHALAGSASKEKKEWLKWFEPLEDYVYIDGQDKIEELLKSYKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLB8</accession>
    <name>A0A1D3RLB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_11757_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000058">
        <property type="protein sequence ID" value="SCN46460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="201" mass="23198" checksum="7C40E0767621E0E5" modified="2016-11-30" version="1">MFKPNILVVDDERFFTSLIADILKESYHISIANNGFEALDKLKKGSIDLILLDILMPDMDGYETCKQIKLSERGHDIPVIFLTIKNEIEDELHGFSLGAVDYITKPISPPIVKARVATHIALAKAHEQLRQHTLELELLVAERTVELTREITEKQKAYEKLHYLANYDPLTQLPNRNLFNERLAYAYKLAKRNNSSFFSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLB9</accession>
    <name>A0A1D3RLB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase/phosphodiesterase (GGDEF &amp; EAL domains) with PAS/PAC sensor(S)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11757_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000058">
        <property type="protein sequence ID" value="SCN46462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="163" mass="18447" checksum="9F52629283F74B17" modified="2016-11-30" version="1">MSTRQFCEKVNSYYLIKQLLREFELSGANLQLEITENLMLEDSSVVMEMLSELRAIGVQLSVDDFGTGYSSLSYLRRFPVDILKIDRSFIQDLNLDSGDDALVKAIIAMGQSLGLKVIAEGVETKEQLQFLQAHECDMIQGYYFSKPVNAEEIERLLAKPLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLC7</accession>
    <name>A0A1D3RLC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00432_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000065">
        <property type="protein sequence ID" value="SCN46473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="57" mass="6370" checksum="80957B8DBF170C24" modified="2016-11-30" version="1">MTIEKKAPKSKSVACKITAEQDARLVKLAEKLDITKSNLISQLMAQGYKDLTKNKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLF4</accession>
    <name>A0A1D3RLF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate-selective porin O and P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_15724_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000085">
        <property type="protein sequence ID" value="SCN46503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920232" evidence="1">
        <location>
            <begin position="28"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="457" mass="50484" checksum="2C63452386300DA9" modified="2016-11-30" version="1">MAMTTKNSGKILALAVSAALGSVSVQAADSELLDTLLKNGAINKAQYNKLSNKVVEEKKEEATDWTNNVKVSVGEKGLKVESADKQFKFQFGGRLQVEANGDIGDDELSQGATEGVEVRRARLYMKGIVWGDYKYMIEADFADNDIAIKDAFLTYKGFDWNNLEITVGHQKQPISMELQESSNDIMFTERSTVNVLTAPAFDRAIGLHFKTSDKDWSAQLGFYGDGMAPEKDGNVDEGWSFASRVTYAPLNTKTHVFHLGAFGGYKGFSDSHSEVKFSSETSHMSNLKLTNVRVTNVDGLGIFGVESAYMLGAFSVQGEYAHEWITRSGGEKGLDLNAAYVQVAWTLTGEARSYKGSDGEFKYLKPSQNFSWSKGTWGAFELASRYGISDIAYGSYKDGTREQDVTVALNWYMNNNVRIMADYRYAFDLAGSGITELNGSDLDHGVHSFTLRTQFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLF6</accession>
    <name>A0A1D3RLF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrite reductase [NAD(P)H] small subunit</fullName>
            <ecNumber evidence="3">1.7.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_06966_2</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.7.1.4" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000090">
        <property type="protein sequence ID" value="SCN46511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03529">
        <property type="entry name" value="Rieske_NirD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017881">
        <property type="entry name" value="NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012748">
        <property type="entry name" value="Rieske-like_NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40562">
        <property type="entry name" value="PTHR40562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13806">
        <property type="entry name" value="Rieske_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02378">
        <property type="entry name" value="nirD_assim_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske_2" evidence="2">
        <location>
            <begin position="3"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="110" mass="12082" checksum="DE7580BAA88E773C" modified="2016-11-30" version="1">MSKWVDICAVTDLPADSGVCALVEDKQVAIFYMPKDNAIFAISNYDPFGKVHVLSRGLLGDIKGEPMVSSPLYKQHFSLLTGKCFEDENVCIPVYAARIKDNRVAVSLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN0</accession>
    <name>A0A1D3RLN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04903_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000068">
        <property type="protein sequence ID" value="SCN46479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="213" mass="23012" checksum="15D21D786313E7CF" modified="2016-11-30" version="1">MSFDIVCFDCDSTLSEIEGIDELANRAGCGTAMAALTNAAMNGEVPLESVYGQRLDLIRPDKAAIAWVADLYIERMVQGAQETFQQLQVQGKQVHIISGGLKQAILPLAALLNIDERHVHAVDVLFDEKGDYAGFNQQSPLARNGGKTEVCLQLNPHKVKLAMVGDGNTDMEAKKAGAFCIGFGGVVARKIVQEQADVFIHEPDLQAVLAYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLN6</accession>
    <name>A0A1D3RLN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_39362_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000173">
        <property type="protein sequence ID" value="SCN46615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="219" mass="25673" checksum="DEFA9A32CDCC02D8" modified="2016-11-30" version="1">MKAGVEFIFTCKPDSHETLYEWVDDFERIGNIEHLTTKKWNGKQHIISDYRIARQVPLRNTDDALYLNFFESTVHCEETGKILHHTAFATPIKVSVETVEDYTAQARTRWKIENENNNTLKNQGYHLAHNFGHGKQFLSMTLLTLNLLAFLFHGILQLMDANYQLVREELGTRKTFFDDIKALTKYHYFESFQALLVFMVEGLEIKPPDQKINARYRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLP0</accession>
    <name>A0A1D3RLP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04566_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000071">
        <property type="protein sequence ID" value="SCN46489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920243" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="4780" checksum="966EBE29437681F3" modified="2016-11-30" version="1">MCLASLFLSIASSAIVSAMQLSVQTNRWKSVAVTVRSIKPSRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLQ3</accession>
    <name>A0A1D3RLQ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Asp_Arg_Hydrox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01013_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000006">
        <property type="protein sequence ID" value="SCN46397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018193">
        <property type="term" value="P:peptidyl-amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007803">
        <property type="entry name" value="Asp/Arg/Pro-Hydrxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05118">
        <property type="entry name" value="Asp_Arg_Hydrox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asp_Arg_Hydrox" evidence="1">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="63" mass="7546" checksum="C86B1E3C9780D128" modified="2016-11-30" version="1">MFIFDDTLSHQSFNQTDEARYCLFVDIVRPSKCHFVMDLFVQLVAIIMQKMNHIFYSSWVPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLT5</accession>
    <name>A0A1D3RLT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_196314_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000187">
        <property type="protein sequence ID" value="SCN46641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="41" mass="4591" checksum="7338CC9EB614FFD4" modified="2016-11-30" version="1">MKIDNIDVEAAVKNTQQLFEIERDISPALKSALEMMVLSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLU1</accession>
    <name>A0A1D3RLU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ORF">BAZMOX_00985_3</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000183">
        <property type="protein sequence ID" value="SCN46632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="83"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN46632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="158" mass="17428" checksum="A642F0F0886A16B7" modified="2016-11-30" version="1">MDKVPLTVVGAEKLKAELEELKTVTRPRIVEAIATAREHGDLKENAEYHAAREQQSFAEGRINEIEGKLANAQIIDVTKIDAQGKVIFGATVEIEDLETEKKVTYQIVGQDEADIKKGRISVASPIARALIGKELEDVVTVKTPNGEVDYEIVTIQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLX5</accession>
    <name>A0A1D3RLX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="5">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="5">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">truB</name>
        <name evidence="9" type="ORF">BAZMOX_57941_2</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000088">
        <property type="protein sequence ID" value="SCN46508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015240">
        <property type="entry name" value="tRNA_sdUridine_synth_fam1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09157">
        <property type="entry name" value="TruB-C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="6">
        <location>
            <begin position="32"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="8">
        <location>
            <begin position="181"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="TruB-C_2" evidence="7">
        <location>
            <begin position="243"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="302" mass="33107" checksum="7096F381BB5AF0A7" modified="2016-11-30" version="1">MARRKKGLDIHGIVLLDKRQGISSNKAMQEVKRLYNANKAGHTGSLDPLATGLLPICLGEGTKVSAYMLADDKRYQTVIQLGVMTDTGDVDGTVLENKPVPVISDQQLAECLASFVGEIEQVPPMYSALKHHGKKLYELAREGITVERKARKITIYALECLASTGNTLTLDVRCSKGTYIRTLAEDIGHYLGCGGTVKELRRTAAGQFLLADARTIEQLQAIEAGEPLCSILIPVDQPLQAMPAVHVSQLEAYLIQQGQQISCSSDIAESEICRIYHDKQFLGLGEMLMNAKIQPRKIFNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ1</accession>
    <name>A0A1D3RLZ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type II secretion system core protein G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BAZMOX_00699_1</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GSP G family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000100">
        <property type="protein sequence ID" value="SCN46518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013545">
        <property type="entry name" value="T2SS_protein-GspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010054">
        <property type="entry name" value="Type2_sec_GspG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08334">
        <property type="entry name" value="T2SSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01710">
        <property type="entry name" value="typeII_sec_gspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="T2SSG" evidence="11">
        <location>
            <begin position="33"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SCN46518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="141" mass="15563" checksum="FF8A8F761CAA6694" modified="2016-11-30" version="1">MKHFKKPMSGFTLIELLVVLAIIGLLAGLVGPQVMKHLGSSKTKAAKVQIEDLAGALDMYRMDVGRYPSTEEGLKSLVEKPANARSWNGPYLRKNNVPQDPWVYDYHYASPGEHGRFDIYSLGADNAPGGEGEDQDVNSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ5</accession>
    <name>A0A1D3RLZ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione synthetase</fullName>
            <ecNumber evidence="2">6.3.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_49042_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="6.3.2.3" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000207">
        <property type="protein sequence ID" value="SCN46674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006284">
        <property type="entry name" value="Glut_synth_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004218">
        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
        <property type="entry name" value="PTHR21621:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02955">
        <property type="entry name" value="GSH-S_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSH-S_ATP" evidence="1">
        <location>
            <begin position="2"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5269" checksum="6058B42AA3B8BEA4" modified="2016-11-30" version="1">MGIDVIGDYLTEINVTSPTCVQELDNQFGLNICAQLMDHIESMLPKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM48</accession>
    <name>A0A1D3RM48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">COG0613, Predicted metal-dependent phosphoesterases (PHP family)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_24970_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000277">
        <property type="protein sequence ID" value="SCN46775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="9"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="292" mass="32585" checksum="4A775D8B676B49AE" modified="2016-11-30" version="1">MNEMNEIKYDLHCHSSASDGALTPHEVVLRAKEHGVTTLALTDHDTIAGLAQARQAANENNLKLISGIELSCTWNKRTFHILGLDIDPNNAELLKGIQTLQDTRLERAHKIAHKLEKNKVPGALDAVLEAAGSGMITRSHFADFLLKNNYVSTMQGAFDHYLGQSKSAFVNTQWAELDNAINWIIKAGGCAVVAHPLRYKLTASWMRRFLTAFKEYGGQGMEIITGRSNPDEVRRAAHFAAQFELYGSIGSDFHNPKNQWVELGRLATLPTNIRPVWQLFTPEKINIIKTMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM52</accession>
    <name>A0A1D3RM52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_34263_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000248">
        <property type="protein sequence ID" value="SCN46734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="5142" checksum="14CB6C6BF354624F" modified="2016-11-30" version="1">MVLTEKVHQVLECAGFQVYSHEQIPSNDAGLALGQLYYAHFYKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM72</accession>
    <name>A0A1D3RM72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_49011_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000292">
        <property type="protein sequence ID" value="SCN46795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="69" mass="7335" checksum="52CFA39A40A15C46" modified="2016-11-30" version="1">MSTKALQKISAEPLTTCPVCNKSELKKKISAAGFRLKGSGWYETDFKSGNKKNVVGSEKPVATAGSSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA7</accession>
    <name>A0A1D3RMA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase FkbM family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_239364_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000163">
        <property type="protein sequence ID" value="SCN46597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="31"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="212" mass="24066" checksum="4E3EECD38DC1D3D2" modified="2016-11-30" version="1">MLSSDILTCWQVFIKQEYDFIVEAHPKVIIDAGANIGLASIYFANKYPNAKIIAIEPEQSNFELLKENIAPYPNVIPVQAALWHKNEEINLVDPGLGKWGFMTEMKNAPENIVGDTCHTVEAMTIDRIMNDYHLDKIDILKVDIEGAEKEVFSNALSWIEKVDALIIELHERMKTGCNRSFYCGSNGFDNEWTQGENVYLSRANYLLKHPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMA8</accession>
    <name>A0A1D3RMA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">16S rRNA (Guanine(966)-N(2))-methyltransferase ## SSU rRNA m(2)G966</fullName>
            <ecNumber evidence="1">2.1.1.171</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_237336_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.171" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000301">
        <property type="protein sequence ID" value="SCN46810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052913">
        <property type="term" value="F:16S rRNA (guanine(966)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="96" mass="11131" checksum="CB4EE34096016B89" modified="2016-11-30" version="1">MSASQIKIIQQDVYRYLAGDAELFDLVFLDPPFAKGLALQALSWLEDKQWLAPQAKIYIEVEKQLQLEGVPENWRLLKHKVAGAVAYYLFERDTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMB6</accession>
    <name>A0A1D3RMB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Replication protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_26729_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000310">
        <property type="protein sequence ID" value="SCN46822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="165" mass="19245" checksum="ECF21E6DE84E564D" modified="2016-11-30" version="1">MADIKKKSVKKAVKKPPGQPIKSIQHDLFSDFLANDISEISNTVDLWERIPKYFLSPQEQKRLRPETGQPDPYTQEYILRGRNGELLPYKVRIQPALIEQPEGGFIAFFPTKAEEVIEEILKKIFTEQNLGIHDVKNRESWVKFSYSMINKELRKNKMQQNTPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD2</accession>
    <name>A0A1D3RMD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation elongation factor P Lys34:lysine transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_02677_0</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000206">
        <property type="protein sequence ID" value="SCN46668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004525">
        <property type="entry name" value="EpmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00462">
        <property type="entry name" value="genX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="2">
        <location>
            <begin position="16"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN46668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="324" mass="36873" checksum="F6FFED0A0B3D5AC0" modified="2016-11-30" version="1">MSLNWQPSCSLELIQLRAKLLHEIRTYFYVNNVLEVETPLLCHSVGTDPYLEYFTSHYSIPSRDYYLQSSPEFAMKRLLAANTGSIYQITKAFRNGESGRYHNPEFTLLEWYRTGFDLQQLMDDVESLLTPLLTVECCSGKAERITYVDVFKNYTGLNALQFDAAEYQACADKLGFPEATQLCALDHAAWLDFLFSHVVQQHLGVARLCMVFDYPACLPSLARLKLNDTRVVERVELFIDGVELGNGFFELTDVNEQIRRFDQDIMHRKNNGAVKIDKDERFLAALHSGLPDCSGIAIGIDRLLMIISQKSAIDEVLAFPIENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMD7</accession>
    <name>A0A1D3RMD7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_506713_0</name>
        <name evidence="1" type="ORF">BAZMOX_86853_1</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Seilhamer J.J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">BAZMOX</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000300">
        <property type="protein sequence ID" value="SCN46806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FMJP01000475">
        <property type="protein sequence ID" value="SCN47050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="3840" checksum="D448160C2FDD5CFE" modified="2016-11-30" version="1">MGIPAQASGKNLTRLINAFGAPIRPRHLAPTQQGVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RME9</accession>
    <name>A0A1D3RME9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_35272_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000185">
        <property type="protein sequence ID" value="SCN46637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920242" evidence="1">
        <location>
            <begin position="27"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="124" mass="13768" checksum="0870E24C8E518AB6" modified="2016-11-30" version="1">MSNITQAAKKSMLLIGTLLLVGCVSAPTLDFSIPVDKIEDFNKCMVSGSLEKLGKNQSPKEFWHGGLSKVFISPKLTKLKLHTPLFESIPEILNMLYADKERLEVPKGAELLSVPSLKIRETER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMG5</accession>
    <name>A0A1D3RMG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Micrococcal nuclease Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products</fullName>
            <ecNumber evidence="2">3.1.31.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01466_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.31.1" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000330">
        <property type="protein sequence ID" value="SCN46853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002071">
        <property type="entry name" value="Thermonucl_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="SSF50199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01123">
        <property type="entry name" value="TNASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="1">
        <location>
            <begin position="18"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="161" mass="18228" checksum="8E3544DA18A4B8CA" modified="2016-11-30" version="1">MRTFLFLVAGLWFPSLVFGLDGGVVRVVDGDTIVVLTDDKTSVKVRLSYIDSPEKSQPLGKKAKQVLSGLVFGQVVHIVEQPKPDRWKRVLGVVFVNDGLNVNREMVALGYAWVYPKYNQDADLPAFQLAAQRAGLGLWRLQADQRIEPWVWRKLARQSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMG7</accession>
    <name>A0A1D3RMG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_84593_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000339">
        <property type="protein sequence ID" value="SCN46872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="4860" checksum="3F155216354E2C0E" modified="2016-11-30" version="1">MYGVGGQVGVSLALAHNEINTPARSITVALIVTILYLPYCCLPVMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMH2</accession>
    <name>A0A1D3RMH2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cardiolipin synthetase</fullName>
            <ecNumber evidence="1">2.7.8.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_129637_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.7.8.-" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000230">
        <property type="protein sequence ID" value="SCN46708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="70" mass="7955" checksum="885878B08F832176" modified="2016-11-30" version="1">MISFKGTHFPKDVSGESLFLRKLVLGIPAQASGKNWFCRKHRLIVGFLSHLWVNSDIIPPLFPNVHKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMI4</accession>
    <name>A0A1D3RMI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiol:disulfide interchange protein DsbD</fullName>
            <ecNumber evidence="6">1.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Protein-disulfide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BAZMOX_11318_1</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-dithiol + NAD(+) = [protein]-disulfide + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:18749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-dithiol + NADP(+) = [protein]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:18753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the thioredoxin family. DsbD subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000355">
        <property type="protein sequence ID" value="SCN46901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase (NAD(P)) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02953">
        <property type="entry name" value="DsbDgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035671">
        <property type="entry name" value="DsbD_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022910">
        <property type="entry name" value="Thiol_diS_interchange_DbsD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32234:SF0">
        <property type="entry name" value="PTHR32234:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0520">NAD</keyword>
    <keyword evidence="19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="18">
        <location>
            <begin position="192"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="SCN46901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="323" mass="34706" checksum="E9307C4021001D2A" modified="2016-11-30" version="1">MFGFYHLELPKSLQSRLHNASDKHRDGSYLGAGLMGVFSSLIVGPCVAAPLAAALMYIGQSGDVILGGSALFVMGFGMGVPLLIIGASAGSLLPKAGHWLNASKSVFGVIMLAVAIWMLERVLAAEIIMFFWAILCIIPAIYLRALDPLPSIDSGWHKLWKGVGVVLLAYGLLILVGLSAGNSNPLQPLKGLSMGATANAQAETSPAFKKIASLAELKQEIQRANANGQWVMLDFYADWCISCKEMEAYTLSKPEVKQALANIVLLQADVTKNTSTDKELLKAFNLVGPPAILFFRLDGQEQGDLRIIGYQDAETFLGQLPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK9</accession>
    <name>A0A1D3RMK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_26985_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000365">
        <property type="protein sequence ID" value="SCN46912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="39" mass="4307" checksum="B35428388996049C" modified="2016-11-30" version="1">MAYQHAVAIGLGVTEYEPNSKAAGEIIELWNALREFTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RML2</accession>
    <name>A0A1D3RML2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase III subunit gamma/tau</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaX</name>
        <name evidence="6" type="ORF">BAZMOX_11843_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DnaX/STICHEL family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000353">
        <property type="protein sequence ID" value="SCN46894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18137">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022754">
        <property type="entry name" value="DNA_pol_III_gamma-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012763">
        <property type="entry name" value="DNA_pol_III_sug/sutau_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021029">
        <property type="entry name" value="DNA_pol_III_tau_dom-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045085">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038249">
        <property type="entry name" value="PolIII_tau_V_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12169">
        <property type="entry name" value="DNA_pol3_gamma3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12170">
        <property type="entry name" value="DNA_pol3_tau_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02397">
        <property type="entry name" value="dnaX_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="49"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN46894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="554" mass="61492" checksum="CDC82D3968CD247B" modified="2016-11-30" version="1">MVAAQSKIYHAAMNHQVLARKWRPHNFTEIVGQEHVSQSLINALRHNRLHHAYLFTGTRGVGKTTIARILAKAINCENLQDFNPCGVCAVCTALDEGRFLDLIEVDAASRTKVEDTRDLLDNAQYAPNSGKYKVYLIDEVHMLSGHSFNALLKTLEEPPEHVKFLLATTDPQKIPATVLSRCLQFNLKRLSISQISEQMAYILNAEKIEFEVSALRLLARAADGSMRDGLSLLDQAIVYGNDVVHTATVSHMLGTIAQQPVEDLLRSLAENNAASVLHKVKEMAELTPDFASILQQMLYFLHRLALVQQVPAIAEADDDADILRELSPLFSAEKLQLYYQIALMGQKDLSLSPDPKSGFEMILLRMLAFSPQKTSANVQKIAPTIAQKSRSAMVSPTEVRAMPTDSKIANKEAPVTANVQLTEVGEELSWHEIVATMSIVGLTRELANNCILEGVDEQQCRLILDPKQAQIRSPRSEEKLQAAVQAYYKRPLKLVIKTEAVVADTPAVQIQKDKINRQQDAVDAIDNDENIQALKANFDARIIPGSIEPVQNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMN7</accession>
    <name>A0A1D3RMN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_259346_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000386">
        <property type="protein sequence ID" value="SCN46940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="71" mass="7930" checksum="D51424F89BC8F00A" modified="2016-11-30" version="1">MLLEQIRDLGVDISSGKLSHILTEDLDDFHTEKDELLRTGSSVSQYIHTDDTGARHKGENGYCTHMVLSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMP9</accession>
    <name>A0A1D3RMP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_86593_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000414">
        <property type="protein sequence ID" value="SCN46971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="48" mass="5339" checksum="693BFE2A366887A4" modified="2016-11-30" version="1">MPSWGSDSVNKLISISISISIAFYQLKRESYDTMTSLSIARFSCLTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMS2</accession>
    <name>A0A1D3RMS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I restriction-modification system, restriction subunit R</fullName>
            <ecNumber evidence="2">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_01466_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.21.3" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000330">
        <property type="protein sequence ID" value="SCN46859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021810">
        <property type="entry name" value="T1RH-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11867">
        <property type="entry name" value="DUF3387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3387" evidence="1">
        <location>
            <begin position="64"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="393" mass="44637" checksum="863BC5663084CDE3" modified="2016-11-30" version="1">MWLTGFDAPPLHTLYIDKKMQGAALMQAIARVNRVYKDKPGGLIVDYIGIGQDLRSAMKDYTESGGQGNVAPDIEEIISAMNAKFEVVNQMFHGFNYAPYFTAQTGGKLKLLLAAQNFILKDEKLKDRFLSEVTVLSKLYVMAVPSYESEVIKDKIAFFQAIKSRINKFTPSGGKTDIQVNTAIRQIVDDALSSDGVVDIFEAAGVDNPSLDILSEEFLLEVKHMEHKNLAFELLKKLLNDEIKTRKRKNTLQGKKFSEMLENTIKRYHNNQIDTAQVIKELAEIAREMNLEDHKAEELNLTPEEYAFYSILSQNSSTQYLEENKMKELIHLIVDIIRKNATVDWNKRADVKAKLRLLVKKVLIKYGYPPDVARIEADRVLEQSELLASELTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT0</accession>
    <name>A0A1D3RMT0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatase NudJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_05055_0</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nudix hydrolase family. NudJ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000270">
        <property type="protein sequence ID" value="SCN46767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004787">
        <property type="term" value="F:thiamine-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03675">
        <property type="entry name" value="Nudix_Hydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033713">
        <property type="entry name" value="NudJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="151" mass="17506" checksum="4A301CBD92435654" modified="2016-11-30" version="1">MVWKPHVTVAAIIEQDQRFLLVEEETPAGIAFNQPAGHLEPSESLIDAVKREVNEETAWQFTPEYLTSIQLWRKNPDFPSFMRVCFVGHCYDHNPEQALDEGIIRTHWLTYNEIVDHKSQLRSPLVLTTIDQYLAGEHYPLTLLTTFLDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMT8</accession>
    <name>A0A1D3RMT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I restriction-modification system, restriction subunit R</fullName>
            <ecNumber evidence="1">3.1.21.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_18360_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.21.3" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01000409">
        <property type="protein sequence ID" value="SCN46964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="59" mass="6739" checksum="4970802519BE1E23" modified="2016-11-30" version="1">MFYGAIRCPLEFWAPWRLESEKGDLAKQFGLAEISKELTDLLSPVRLLDILQTSPYSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMW5</accession>
    <name>A0A1D3RMW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_364641_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000444">
        <property type="protein sequence ID" value="SCN47012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="45" mass="5115" checksum="6C3A43F25FB057F5" modified="2016-11-30" version="1">MANFPVAYCGLKIITSLSLRFPDFHRLENRGSLVSRITRFISSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMX0</accession>
    <name>A0A1D3RMX0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_04389_3</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="FMJP01000477">
        <property type="protein sequence ID" value="SCN47055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="452" mass="51267" checksum="1548ACB9728F79AF" modified="2016-11-30" version="1">MFKETISESLLADIMSVSKRTVGSWKKNGKVNPLKNGLYSLSDLVYFPQVKAMMESNWDKEQEIKPIKKYSSIELFAGAGGLAIGLEKAGFNAVALSEIDKNACSTLRKNKPEWNILEGDVSNIDFTVYKNIDFLSGGFPCQAFSYAGNKLGFKDTRGTLFFEFARAIKEIKPKVFLGENVKGLLTHDNGKTLETIKSVIQGLGYTLIEPRVLKAIFYRVPQKRERLFLVCIRNDLVKYNNFEWPEPFNRILTVKDALKKGALYESDCPDSQGQVYPERKKKILSMVPPGGCWVDLPDDIQREYMQKSYFMGGGKTGMARRLSYDSPSLTLTCAPAQKQTERCHPEETRPLTVREYARIQTFPDNWGFVGSVSSQYKQIGNAVPVNLAHAMGKKLISLLNNIENRIEVFESYQIEEKEKTVIQMSLFEPKGKYKLKTHNKKIQRTQKATPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMY5</accession>
    <name>A0A1D3RMY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ser/Thr protein phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_16778_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000435">
        <property type="protein sequence ID" value="SCN47006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="36"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="242" mass="27852" checksum="337A81112808B068" modified="2016-11-30" version="1">MRINYFSEIHLEFGPADLPSNDAGIIVAAGDIGIYDQGIEWLLATNKPVIYIAGNHEFYTREYHNTLRMLRDKCANTNITFLENNTVKFKGVRFIGCSLWADLFIEGEATADALCLSLNDFRKIRYADGMYNPKQFTALYNYSKIWLEKELTKPFDGQTVVVTHHAPTQWSWYDSPNTIKKLAYCNDLKSLFHEHDITIWFHGHTHSIGDYRIAGARILSNTRGYVGRRVVDNFDMNKIVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN01</accession>
    <name>A0A1D3RN01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA invertase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_00523_8</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the site-specific recombinase resolvase family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000315">
        <property type="protein sequence ID" value="SCN46837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006118">
        <property type="entry name" value="Recombinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006120">
        <property type="entry name" value="Resolvase_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02796">
        <property type="entry name" value="HTH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00397">
        <property type="entry name" value="RECOMBINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0229">DNA integration</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="7">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-serine intermediate" evidence="5 6">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606118-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN46837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="184" mass="20310" checksum="664404396382F1D1" modified="2016-11-30" version="1">MKIGYARVSTAGQDTAIQIDALKNASCESIYEETASGAKVGRTELEQCLKSLRRDDILVVWKLDRLGRSLQHLLQIINNLEERGVGFISLTESINTTTSTGKLIFNIFSSLAEFERALIKDRVIAGLESARKKGRVGGRPLALNEKQLQLAIAMFNGGALKSDIAKHFNVSRQTIYSVLKESNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN27</accession>
    <name>A0A1D3RN27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation elongation factor G paralog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_14423_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000403">
        <property type="protein sequence ID" value="SCN46959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFG_IV" evidence="4">
        <location>
            <begin position="162"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="EFG_C" evidence="3">
        <location>
            <begin position="282"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="383" mass="41900" checksum="D89398703B3DD1CD" modified="2016-11-30" version="1">MDDRYGALTFVRIYSGKLNKGDTILNSFTGKTERVGRMVEMHADERIEIDSAQAGDIIAIVGMKNVQTGHTLCDPKSPATLEPMVFPDPVISIAVSPKDKAGSEKMGIAIGKMVAEDPSFRVETDDDSGETILRGMGELHLDIKVDILKRTHGIDVEVGKPQVAYRETITKTIEDSYTHKKQSGGSGQFGKIDYRIEPGEPGSGFVFESKVTGGNVPREFWPAVEKGFKSMIDTGVLAGFPCLDFKVTLLDGGFHAVDSSAVAFEIAAKSAFRQSIPKAGPQLIEPIMHVDVFTPEDHVGDVIGDLNRRRGMIKSQEAGVTGVRIKADVPLSEMFGYIGDLRTMTSGRGQFSMEFSHYLPCPKNISEEVIKEVQERNKAKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN29</accession>
    <name>A0A1D3RN29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Replication protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_34121_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000500">
        <property type="protein sequence ID" value="SCN47090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="278" mass="30473" checksum="B97BC7D4ED2B6617" modified="2016-11-30" version="1">MSRIDILNAFEQEPQPLDFVLPSFLAGTVGALIAPGATGKSYFALQACMSIACAVAGGDLLGLKSKSGLVVYINAEDPEVIVRNRIFAIGKKLNQQAKESIAKNLFIEPMLGKRLDIVDDAQRKRIIGYCIGARLIVFDTLSRIHTLDENSNSHASQIIGMLEQIATETGASVLFLHHVSKASTIGGMAELQQAARGASALIDNARWCGYVAKMTKDEAKNYSENHFNKQAIDPDFCKNFIKFGVSKQNYGQPFLEKWLKFCDGGTLMSAEILRLIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN46</accession>
    <name>A0A1D3RN46_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <shortName evidence="5">AcCoA synthetase</shortName>
            <shortName evidence="5">Acs</shortName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetate--CoA ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Acyl-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">acsA</name>
        <name evidence="9" type="ORF">BAZMOX_39996_0</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="5">Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01000349">
        <property type="protein sequence ID" value="SCN46887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01123">
        <property type="entry name" value="Ac_CoA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="8">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="6">
        <location>
            <begin position="87"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="7">
        <location>
            <begin position="533"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="5">
        <location>
            <begin position="195"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="389"/>
            <end position="391"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="413"/>
            <end position="418"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="502"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="528"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="586"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="5">
        <location>
            <position position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN46887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="622" mass="69839" checksum="91924A597612560F" modified="2016-11-30" version="1">MTEHQTYEHQVHPVKDHIAKNAHINNEQYLALYQQSIEQPETFWAEQADKFLDWQKPWDKVLEYDYPKGEIKWFEGGQLNVSVNCLDRHLATRGNQVALIWEGDDPANDKKMTYRELHQEVCRFANVLKAQGVQKGDRVCIYLPMIIESAVVILACTRIGAVHSIVFGGFSAEALKDRINDSDCKLVVCADEGYRGGKIIPIKATVDKAIASCPCIENVIVIKNSGNTVAWNDSYDVWYHQAMSEVSAECEPEWMDAEDPLFILYTSGSTGQPKGLLHTTGGYLLYAAMTHKYIFDYQEGEIYWCTADIGWITGHTYMIYGPLCNGATTLLFEGVPTYPDASRFWQVVDKHQVNIFYTAPTALRALMAQGDQYLENTSRSSLRVLGSVGEPINPEAWEWYYELVGKENCPIVDTWWQTETGGILITPLPGATELIPSSATRPFLGVKPAILSNEGQVIEDDTEGVLVMERPWPGQARSIYGDHQRFIDTYFKNYPGYYFTGDGARRDERGYYWITGRVDDVINVSGHRMGTAEVESAIDEHPLVAETAVVGYPHTIKGQGIYAYVTLHVGVEGTEALKKELVKLVRADIGSIASPDLIQWSAQLPKTRSGKIMRRICANCGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN63</accession>
    <name>A0A1D3RN63_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_01036_3</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000535">
        <property type="protein sequence ID" value="SCN47131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="196"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="253" mass="29011" checksum="FC273F8297CAF62B" modified="2016-11-30" version="1">MQPASSAIDRSQYPKHIAIIMDGNGRWAKKRHLPRVMGHPAGVKAVKRVVEFCAQEEIQVLTLFAFSSENWRRPKEEVAKLMDLFMSTMQKEVNRLDKNNIRLRFIGDRTEFSDKLQQKMVDSERQTENNTGLTLVIAANYGSHRDMTLAVQNIARKIQEGTLVPDDIDETLIASGLSISDLPEPDLFIRTGGEQRISNFLLWQLAYTELYFTSKLWPDFNAATMQEAIDDFLTRERRFGRTSEQVQKLSKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN70</accession>
    <name>A0A1D3RN70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase eubacterial/eukaryotic</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_02217_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000520">
        <property type="protein sequence ID" value="SCN47113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="217" mass="22847" checksum="472ECD0982FC9A11" modified="2016-11-30" version="1">MFTGIILAVGKITQIEQKAGDVRLSIDTGKLSLVDAALGDSIAVNGVCLTAIELSAHGFVADVSNETLARTNLKLAASGTPVNLELALTPQTRLGGHIVSGHVDGLAVLLDKKPDGRSIRSKFKVPNELAKYIAEKGSICINGISLTVNKVDGAVFSVNIVPHTLKETTLGNIEVNDKVNIEVDLLARYMERLMKGEAAATCAAGVTTELLRESGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB1</accession>
    <name>A0A1D3RNB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_20759_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000529">
        <property type="protein sequence ID" value="SCN47126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4386" checksum="405A7DF12D2C5817" modified="2016-11-30" version="1">MTTIIHNTDGSITGSVARIGESEVRLVFRHNYPAKAINCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB6</accession>
    <name>A0A1D3RNB6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00840_5</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000567">
        <property type="protein sequence ID" value="SCN47180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="66" mass="6846" checksum="60EB90B8A7AE69A5" modified="2016-11-30" version="1">MGLNIESESSKGVRGYVAIMGMLIIILGMVASVQADGSVIPDIMMLVGLIVVLVAEKSSLNEGPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNE1</accession>
    <name>A0A1D3RNE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_161992_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000483">
        <property type="protein sequence ID" value="SCN47069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="60" mass="6924" checksum="610D9C869C5F2E14" modified="2016-11-30" version="1">MAWQIKFDEAAKKNLTKLGEQIAKMKLNRSGKLTNKKTLQQGKRTAIIEQNKKLEILLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNI1</accession>
    <name>A0A1D3RNI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_179333_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000598">
        <property type="protein sequence ID" value="SCN47232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="88" mass="9652" checksum="B8406354368449E9" modified="2016-11-30" version="1">MEMEVTGKISQWGNSLALRVNQKVADTLSVAAGSVVSLNLDKKNKVLTVKNIEKKEAWPFKEADLLVGMNAENSHSDLLTPLLESEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNL4</accession>
    <name>A0A1D3RNL4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cobalt-zinc-cadmium resistance protein CzcA Cation efflux system protein CusA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_218693_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000630">
        <property type="protein sequence ID" value="SCN47271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="190" mass="20670" checksum="1990FED3039C1FAC" modified="2016-11-30" version="1">MLTHDVYYVLGGLYEQQRIAFHDLIIVFIAAIALVFILLLYLYEHFHVALAMMLTTLSAVAAVFIGLWLTGTELNITAMMGMTMVIGIVTEVSIFYYSEYQSLPESELGIQRMIAAGNNRMRPIAMTTVAAILALMPLAMGIGAGSEMLQPLAIGIVSGLIVQMPLVLVLLPALLKILPSIGETNLAKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNP2</accession>
    <name>A0A1D3RNP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_08714_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000645">
        <property type="protein sequence ID" value="SCN47300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="374" mass="42061" checksum="A762535AF5CADD88" modified="2016-11-30" version="1">MIILDIDNDPKDKQLTIKEAKALLESKGISAMILPSKSNQIEKFTDSGKSKGIKDRYRIVIPTKTAIRNNTDEDTYEEFQKLTVNALGLTGSIDTSALKDKARFYYQSPLEAVPVVVKADRVMDISNIENKAIQNVTQARAVKEAQRLKMEQIRADIKKYRIVSMPTSNNLTYVDAEELMDVPITMLIHKFEGGEEATEGSYKYIKTDATKYSIIDDKLAHDFKNDVTYNSLTYLQMQFETNNLNIIARELEKALGGTYIRVNTEAVKTAVADALETATNDKTFEANIKEYFGCKFVKLDKDSIKIADQQISLKDIGIDKGKVVDTLKSNRAIEAQKKAEAVKAKEVESTLDPKQKKEPKQKNQSHSQGGGYHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS2</accession>
    <name>A0A1D3RNS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_140368_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000671">
        <property type="protein sequence ID" value="SCN47331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="74" mass="8484" checksum="C5141608800A0A7A" modified="2016-11-30" version="1">MTLLAKLLGKQSATGRLFGSLQVDSVKARELLDWKPVITMDEQLKKTSGYLLTYLLTYLLTYLIRLSCLYEKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNS4</accession>
    <name>A0A1D3RNS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TldD protein, part of proposed TldE/TldD proteolytic complex (PMID 12029038)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_01495_2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000666">
        <property type="protein sequence ID" value="SCN47323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="40"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="129"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="246"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="482" mass="51702" checksum="96F2317ACAE65E93" modified="2016-11-30" version="1">MDNTVLQLAKQAILVPTGLQEKDIHRVLDQLISGAVDDGDIYIQSSHYESWVLEDGIVKEANHNIEQGAGVRALSGEKTGLAYSDKIELAELLTAAKNVRAIARQGQNAKVAMTPKTGVIKQLYAPLNPLRSLSDQEKVDFLRKIDVETRKIDPRIEQVIISLVGVQEHILIANQGSSLLGDVRPLVRMNVSVIVADKGQREQGSMGGGARSDYNYFFDQDRALGYAQEAVRQALVNLEAIPAPAGSMTVVLGSGWPGILLHEAIGHGLEGDFNRKGTSAFSGRIGERVASSLCTIVDDGTLDNRRGSLSIDDEGTPTQCTTLIENGILKGYMQDRLNARLMKTQSTGNGRRESYAHTPMPRMTNTYMLAGESDPEEILRSVKNGLYAKNFGGGQVDITSGKFVFSASEAYLIENGKITRPVKGATLIGNGPEVLTRVSMVGNDLELDSGVGTCGKEGQSVPVGVGQPTLKIDALTVGGTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNT5</accession>
    <name>A0A1D3RNT5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisF</fullName>
            <shortName evidence="9">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisF</name>
        <name evidence="11" type="ORF">BAZMOX_48678_1</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8 9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000583">
        <property type="protein sequence ID" value="SCN47209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="258" mass="27908" checksum="683B6052B0EB7BB9" modified="2016-11-30" version="1">MSLAKRIIPCLDVDNGRVVKGVKFVDIRDAGDPVEVARRYDREGADEITFLDITATHHDRDTIVHVVEQVASEVFIPLTVGGGIRKLEDIRCMLNAGADKVGINSAAVFNPEFVCEAAEKFGSQCIVVAIDAKKVSRVGEANRWEIFTHGGRKETGINAIEWAKKMVDYGAGEILLTSMDRDGTREGFDLDLTRTISEAVTVPVIASGGVGNLQHLADGVTQGKADAVLAASIFHFAEYSVQEAKEHMASQGIEVRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNU4</accession>
    <name>A0A1D3RNU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_114231_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000680">
        <property type="protein sequence ID" value="SCN47343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="70" mass="8290" checksum="BC12ECD3B6CA0B6D" modified="2016-11-30" version="1">MFFKVYTNKTADNAVTFLDHCKSYFPFYISHVLTDNGAEFTDRFTRKKNKPSRNHLFDINTFANFDLISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNW2</accession>
    <name>A0A1D3RNW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_501764_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000674">
        <property type="protein sequence ID" value="SCN47334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="37" mass="4036" checksum="996201DEA6926C79" modified="2016-11-30" version="1">MILCTLVNKGELSQNLPGNATGAQQLTYACDRTLQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNX9</accession>
    <name>A0A1D3RNX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_48620_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.1.2.6" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000687">
        <property type="protein sequence ID" value="SCN47354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="12"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="238" mass="26090" checksum="646D599E0617DFE3" modified="2016-11-30" version="1">MIFRQLFEPDTCTYTYLIACEVSKKALLIDTVATELKHYIELLGSLDLTLIYTLETHVHADHVTGTSLLRDQLNCKSIVHRDAGAMCADLLVTDGVVLQVGGIEIKILHTPGHTSGCVSYLIGDRVFTGDSLLINGCGRTDFQQGDTATLYNSVTEKLFTLPADTLVYPGHDYNGKRVSNIAQEIALNARLGQQKTCAEFIEIMANLNLPYPKYIDAALPANQACGKIETSQEPLRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNY7</accession>
    <name>A0A1D3RNY7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_204620_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000712">
        <property type="protein sequence ID" value="SCN47392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="87" mass="10071" checksum="AE17C5204781EA9F" modified="2016-11-30" version="1">MDVNKKNDCGDTPLIVTCQQTTLETEEEAVKFISYLWQSSSNLKKSNDFGKTAMNYAESNGLKKIIETLEYIQWKILYDSLYEAFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP26</accession>
    <name>A0A1D3RP26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobile element protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_515977_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000758">
        <property type="protein sequence ID" value="SCN47441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="40" mass="4807" checksum="D4828B782F9DEF04" modified="2016-11-30" version="1">MISFKGTHFPKDVILYAVFFYVRYGVSYRDLEEIMEERGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP71</accession>
    <name>A0A1D3RP71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00950_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000793">
        <property type="protein sequence ID" value="SCN47500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="50" mass="5455" checksum="6BC68BA78B6BFB1C" modified="2016-11-30" version="1">MKENEIKCVLCGLSVEINGFTVNTTEGLKLFCCAGCVSVYRLLNGDKLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP93</accession>
    <name>A0A1D3RP93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FeS_assembly_P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00412_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000688">
        <property type="protein sequence ID" value="SCN47359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017776">
        <property type="entry name" value="FeS_assembly_SufT_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03406">
        <property type="entry name" value="FeS_long_SufT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="86"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="182" mass="19816" checksum="8A53C8E0D5160D3C" modified="2016-11-30" version="1">MSERETITLTRDVNVVLIPDGNHGTLSKGKEVTIHQALGNNYTVVTEHGHMVRIASTDADALGKEVHELHTLVSENSAEAVEKNCWEVMKTVYDPEIPVNIVDLGLVYNCQVESVAEGENDVHIMMTLTAPGCGMGPVIQGDVEKAIRALPGVKSVNVEIVLDPPWSREMMSETAQVQLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB0</accession>
    <name>A0A1D3RPB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_10012_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000806">
        <property type="protein sequence ID" value="SCN47531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01920">
        <property type="entry name" value="Helicase_Rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005752">
        <property type="entry name" value="Helicase_Rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="9">
        <location>
            <begin position="3"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="10">
        <location>
            <begin position="282"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="504"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="668" mass="76206" checksum="1C8602FC5E0A4A99" modified="2016-11-30" version="1">MATKLNPQQQTAVKTIDRPLLVLAGAGSGKTRVITEKIAYLVKQGLPARHIAALTFTNKASREMKARVSKLLDDKELRGLRVSTFHSLGLEILRKEHKTLQYKAGISLFDEQDKITLLKNLITHSSQNYDIDAVNIYSGLIGQWKNSFVTPKQALSLANAEEQEAAQIYVDYTRSLKAYNAVDFDDLILLPVLLFQQFPETLEKWQNTIRYLLVDEYQDTNITQYQLVKLLVGKLGKFTVVGDDDQSIYAWRGAHPENLAQLQKDYMRLEVIKLEQNYRSYGRILKVANQLIANNPHTFEKKLWSDMGYGDPLRVLAHKNDLEEAKQVVAEIVHHKFKTGGCYGNYAILYRSNHQSRLFERSLGEQDVPYFITGSASFFSYAEIKDILSYLRLFVNPDDDAAFLRVVNTPRREIGPSTLEKLGAYASGRHISLFSACSEMGLKPLLSEQALARLQKFCQWTLRTSAEIQSGDTFAVMHAFIQQINYHQWLHENSTSQAAAERKIKNVDELLEWLQRLAEKAEDSENTLEAIVAKIQLLDILDRNQEEEADSQVSLMTFHAAKGLEFPHVFLIGFEEDILPHQNSVETGNIEEERRLAYVGITRAQHTCTFSYCTHRKRYGDVSESAPSRFLEELPEEDLEWPSKNPVDKEEQKVRGKANLAHLKSMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB8</accession>
    <name>A0A1D3RPB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipopolysaccharide core biosynthesis glycosyltransferase, group 2 family protein</fullName>
            <ecNumber evidence="2">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_03110_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.4.1.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000634">
        <property type="protein sequence ID" value="SCN47287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="253" mass="28980" checksum="C16667812B7987C6" modified="2016-11-30" version="1">MTNTKIKNISCVIIVKNAELTIKDTLDSLADFDDIVVYSNGCTDKSNEIAKKYSNVNLIQGEFLGFGATKNKAANLSKHDWVLSLDADEVLSEDFIKKLKKITLNTDNIYTILRENFYKNVQIKHCWGNDIITRLYNKNLTAFTNKNVHESIISDGFNIIHFSDPIKHYPYSTITDFIIKLDRYSTLYANDNAGKKKSSPLKAILNSNFAFFKTYFIKMGFLDGYPGLIIAFSHMATTFYKHMKLYEKNKTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPB9</accession>
    <name>A0A1D3RPB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_412905_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000795">
        <property type="protein sequence ID" value="SCN47504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4519" checksum="68CE93D1C724D672" modified="2016-11-30" version="1">MRLEPLISRKWPILPGKYMQVLTISHKMADYFAFPLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPD7</accession>
    <name>A0A1D3RPD7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_26807_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000652">
        <property type="protein sequence ID" value="SCN47307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="5"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="207" mass="22900" checksum="2179639CFEABB65D" modified="2016-11-30" version="1">MKNIKLVSIWNPKGGQGKSMLAINLAAAAVEIGIKPLIICQDPQGTSINYYKGGNLPFEVIGQIPKEKPDADIIFFDHQASDWEVPSNSLLLMPLKPARDQYATYIDAFKRAESIGKNIITVVTDGSGHRQSEKATVEYLEEQGAFIIPSSGVFSRASNEYRTIFDVALNKAYKVGERRREMSKILGALLIEQSETNHTKEDKKDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF4</accession>
    <name>A0A1D3RPF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_241696_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000794">
        <property type="protein sequence ID" value="SCN47502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021979">
        <property type="entry name" value="DUF3584"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12128">
        <property type="entry name" value="DUF3584"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="194" mass="22972" checksum="029FA0DC6F8F531D" modified="2016-11-30" version="1">MPKSRVTDSFVKHYLPRESSYIIFEYQRHEQTCMVAIYASTNDEGLCYRFIDKGFEPEDFIEQHEDGAKYPVSCRQLKSHLVTRQVQHSNQVTACSDYRTIIQNLPHNKGQDMRQLIARYSFCQGSSGQRLKDIEKIITGMFMRSTDFADLREMLVNCIDENRESIALELQMETLDNWYKEYRAYLQVEQERPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPF5</accession>
    <name>A0A1D3RPF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Conjugative transfer protein TrbF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_02191_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000875">
        <property type="protein sequence ID" value="SCN47615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16425">
        <property type="entry name" value="TrbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035658">
        <property type="entry name" value="TrbF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007430">
        <property type="entry name" value="VirB8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04335">
        <property type="entry name" value="VirB8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="VirB8" evidence="6">
        <location>
            <begin position="22"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN47615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="231" mass="26991" checksum="5E209B464AB176EC" modified="2016-11-30" version="1">MKEAKTAKWENENPIPETPYQRAEQVWDERIGSSRKQAENWRIAAFGSMFISLVSVGGMIYLGQLPKTEVEVVQVDQLGNARYSGRAGQSMAEWRPSEKQIEFHLRRFLRMTRSLSSDMMVVRQNWLDAYNYIADEAVNQLNSETRALSPFKRMETQTVSISIEDTLRLSPDTWQIDWSEQIWSKKGDMLGKEHWRGTFKVEMQIPDSKEKLAKNPLGMYITHYSWSKVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ5</accession>
    <name>A0A1D3RPJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_54488_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000896">
        <property type="protein sequence ID" value="SCN47655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="43" mass="5065" checksum="C00A0A07B5A6D65A" modified="2016-11-30" version="1">MINTNSFIALNVVDKYCLHNLQELSKLRNEYLSKLSKLFVYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPJ9</accession>
    <name>A0A1D3RPJ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">BAZMOX_04315_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000822">
        <property type="protein sequence ID" value="SCN47552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="103" mass="11596" checksum="BCB8B22E5FDDD49E" modified="2016-11-30" version="1">MSSQTIRISLKAFDHKLIDQSAGEIVETAKRTGAQVKGPIPLPTKHERFTILTSPHVNKDARDQYELRTYKRLLDIIEPTDKTVDTLMKLDLAAGVDVKIKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPK7</accession>
    <name>A0A1D3RPK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-nitrophenylphosphatase</fullName>
            <ecNumber evidence="2">3.1.3.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_04294_3</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.41" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000755">
        <property type="protein sequence ID" value="SCN47438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="263" mass="28412" checksum="B388D45EC766D6FD" modified="2016-11-30" version="1">MDGVLWHGEQAIAGLSDFFQLLREQDMPFILATNNASHTAEQYVKKLARMGVSIKQEEILTSGMATALYLAQHKDPANTRIFVLGEQGASQPLLEQGFTLTGIYQLNSPETPNQGADIVVCGKDETITWDKLSTATLNLQAGAEFIATNADTTLPTERGLVQGNGAILAALHAATGRTATVIGKPEPIMYQQALALLGSTPENTIAIGDRLDTDILGAVRTGMRSLMVLTGTSKREDLQNIDFSPTWIMQDLQAATEALRERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN1</accession>
    <name>A0A1D3RPN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_20798_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000894">
        <property type="protein sequence ID" value="SCN47651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="259" mass="30451" checksum="83AB8B5698A54813" modified="2016-11-30" version="1">MNAKYLELVLFLDDSSKNIQSFMRGELLPFGQDTYIDKGPIFDALRQSDRYDTVDMLLQVLLPALCKLSRRLFQDHLPGGKLHDLSEEIKQKVRTAPKTSCYAESVFGQLDCLLRMKPSTKTLPAESCIMFLNNKTLSWLEQKDSEEQKRLLRMASKSVKKLREKYKSRLQEIEESRRVAMNGKIAQLEQLRREKIRKRERYTSDIIHHELWQSETEVDNMILSYIKKNEKVEALKAQLKFRKEVLNQIPDDKTVFLHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN2</accession>
    <name>A0A1D3RPN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_531169_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000895">
        <property type="protein sequence ID" value="SCN47653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="64" mass="7228" checksum="71D593C01609C9C0" modified="2016-11-30" version="1">MANFPVAYCGLKIITSLSLRFPDFQRKAEGKALHDHLYSDVGRDVIATVYFFANSESSLLKYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ3</accession>
    <name>A0A1D3RPQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_165327_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.4.2.18" evidence="4"/>
    <dbReference type="EMBL" id="FMJP01000920">
        <property type="protein sequence ID" value="SCN47680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_3" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="61" mass="6096" checksum="664F8999A8AB05BA" modified="2016-11-30" version="1">MLKSVLDNQPGPALDIVALNAGAAIYAAGLVDSLAAGISKAQEVIASGAAKEKLNALVNFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ7</accession>
    <name>A0A1D3RPQ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="13">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">leuB</name>
        <name evidence="16" type="ORF">BAZMOX_11064_1</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="13"/>
    <dbReference type="EMBL" id="FMJP01000947">
        <property type="protein sequence ID" value="SCN47725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01033">
        <property type="entry name" value="LeuB_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="PTHR42979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0520">NAD</keyword>
    <keyword evidence="10 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="15">
        <location>
            <begin position="4"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="282"/>
            <end position="294"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SCN47725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="365" mass="39359" checksum="10C98D135A76ACF9" modified="2016-11-30" version="1">MTQKIAVLPGDGIGPEIVAEAIKVLDYLNADMGLDIEFEQGLIGGAAYDASGSPFPEATLNLVKQADAVLLGAVGGYKWESLDIAVRPEKGLLGLRSELELFSNLRPAILYPQLAEASTLKPEVVAGLNLMIVRELTGGIYFGQPRGVRVLENGERQGYNTLVYSESEIRRIAHSAFKIAQKRDKRLCSVDKANVLECTELWREVMDEVAKEYPDVALSHMYVDNAAMQLVRAPKQFDVMVTTNMFGDILSDTASMLTGSIGILPSASLDINGKGMYEPIHGSAPDIAGKGIANPLATILSAAMMLRYTFDQAGAADRIEQAVNDALNSNARTADIYSEGMKQVSTSEMGDAVVNALKVRAQNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPS1</accession>
    <name>A0A1D3RPS1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="13" type="ORF">BAZMOX_00950_2</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="FMJP01000793">
        <property type="protein sequence ID" value="SCN47498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="12">
        <location>
            <begin position="340"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="266"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SCN47498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="462" mass="52219" checksum="C1ABAC5D7F2510C5" modified="2016-11-30" version="1">MLKIYNTLSREKEVFTPKVEGKVGMYVCGMTVYDYCHIGHARVMVVFDIVARYLRYSGYDLTYVRNVTDIDDKIIQRANENKEEISELTGRFIDAMHEDERELSVLPPDIEPRATKSMDDIILMITALFEKGLAYIGSNGDVFYAVDKFANYGALSGKKLDELQAGERVDVNLAKKNPFDFVLWKKSKADEPYWNSPWGRGRPGWHIECSAMATRCLGHHFDIHGGGMDLQFPHHENEIAQSEGATGEKFVNVWMHNGFVRINEEKMSKSLGNFFTVREVLKQYRAEIVRFFVLSSHYRSPLNYSDEQLDDAGSAVTRLYTALRGVVVATDVQATDYTLRFKQAMDDDFNTAVAVAVLFDMARELNKIKNNDVELAAQLAAELKELSSVLGILQDDPDEFLKTADGTQDSGLAEQAIEALIAQRIAAKKNKDWALADKIRDDLKAQGIVLEDVATGTSWRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPV8</accession>
    <name>A0A1D3RPV8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_09834_2</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000773">
        <property type="protein sequence ID" value="SCN47467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="229" mass="25580" checksum="D73D21803805E076" modified="2016-11-30" version="1">MLNHSYTTAVDSSLRQPKFTPGLDYKTTGILFIAGTTLVLASISWQPSNQNSSDFATYENKPNQLLIIDQAPRIIEEKNTTDSTTIPYSAYASLVSSALGLGKSDIARILGVSRPTLYSWIKGNSEPRESNHPERLRTLGELVREICGETERPLYHRFVEEPLPGETNSILSLLLAKKWGSERLQQLLAEARRLTTERDQRLGHAIPVKTSRSRQESNLLDNSIASNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPX3</accession>
    <name>A0A1D3RPX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_46996_1</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000956">
        <property type="protein sequence ID" value="SCN47741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012042">
        <property type="entry name" value="NeuTTM/CthTTM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40114">
        <property type="entry name" value="PTHR40114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016487">
        <property type="entry name" value="CYTH_UCP016487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="2">
        <location>
            <begin position="2"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016487-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="155" mass="17958" checksum="3E58BE1F05B6B2B7" modified="2016-11-30" version="1">MAIEIERKFLLANDSWRALVTKSINYRQGYLSSDEHSSVRVRVSDDTAKLNIKSATIGSQRQEYEYDIPLADAHELLTTLCHKPLVEKTRHLVVIKQHTWEIDEFKGENAGLIVAEIELSTVDEDFDKPSWVGQDVTEDIRYYNNQLSKKPYTTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ19</accession>
    <name>A0A1D3RQ19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cob(I)alamin adenosyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_11216_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.5.1.17" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01001032">
        <property type="protein sequence ID" value="SCN47845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="178" mass="20239" checksum="30762A1360090D73" modified="2016-11-30" version="1">MKARDRRQGIVLVNTGEGKGKSSSALGMVFRAAGWDMKVCVIQYIKGKWQTGEQKAAERFDNIEWHVLGDGFTWDTKNPEQDIKTSREIWEFSKQKILSEEYDFVLLDEINYCCGYNWISGQEIADFIIHEKPPWMHLVLTGRNAAPEVIEAAHTVTEMAKVKHAYGQGIKAAQGVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ35</accession>
    <name>A0A1D3RQ35_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable endolytic peptidoglycan transglycosylase RlpA</fullName>
            <ecNumber evidence="3">4.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rlpA</name>
        <name evidence="6" type="ORF">BAZMOX_03760_1</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the RlpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="3"/>
    <dbReference type="EMBL" id="FMJP01000816">
        <property type="protein sequence ID" value="SCN47547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02071">
        <property type="entry name" value="RlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034718">
        <property type="entry name" value="RlpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012997">
        <property type="entry name" value="RplA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00413">
        <property type="entry name" value="rlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPOR" evidence="5">
        <location>
            <begin position="183"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="263" mass="29174" checksum="E6057E7F56D964F2" modified="2016-11-30" version="1">MGKFILLLNLSLLIACTTQEKIVVPIDIVDGRPDQVSVDIATIPDAVPQYEPWSKSVNPKKYTVLGKEYQVLSTNKGYMKQGIASWYGTKFHQRKTATGEDYDMFAMTAAHKTLPIPSYVRVTNLNNQQTVIVRVNDRGPFHEHRIIDLSYAAAVKLGLEKAGTGFVEVVAVQAGEVSGTVPSAQAKHVYLQIGAFSEQKNALNLQHRFAELRLTTSRIVSAQTRERSVYKVQVGPVASVIEADEIIEKIKNLGIYKSHFISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ75</accession>
    <name>A0A1D3RQ75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_121048_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001028">
        <property type="protein sequence ID" value="SCN47841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="46" mass="5438" checksum="9A6135FCDFC5AAE7" modified="2016-11-30" version="1">MNLTLRIKQVVGLVQGRHHHYLIAMLLDIAHEKLFIWHKTTITHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ81</accession>
    <name>A0A1D3RQ81_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="1">4.2.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00676_7</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydroxymethylbilane = H2O + uroporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01001011">
        <property type="protein sequence ID" value="SCN47814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042">
        <property type="entry name" value="PTHR38042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEM4" evidence="2">
        <location>
            <begin position="3"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="162" mass="18252" checksum="D2BE8199108B8A11" modified="2016-11-30" version="1">MFLQHIEQYQYVFFISVNAVNFAYEILNHDFEYLKHVKCIAVGLATYSKLVQFGITNILLPDTGFNSEGILAIPDLQDLDSQSCLIIRGVGGRKLLANTLRARGALVDYMEVYTREPVSYPRESINLAFADGNLDVVVIYSVEALHNLVQLAVEVNKKITYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ85</accession>
    <name>A0A1D3RQ85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_32578_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000937">
        <property type="protein sequence ID" value="SCN47709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920272" evidence="1">
        <location>
            <begin position="25"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="134" mass="14479" checksum="187772D1D1B6E024" modified="2016-11-30" version="1">MIKNKSLKLVCLIVSVGFTGSVFAYGTSATNNGCKKPKFKTFTPAHKSEVDPESEISFTVSGYADPATIKATAKKIPLEVDTEYKISFYAVKAKLPASLNGKYARIHVQADAMLGCTGKDGWLLKIRDKAAEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ88</accession>
    <name>A0A1D3RQ88_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA mismatch repair protein MutL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_113537_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000992">
        <property type="protein sequence ID" value="SCN47782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="128" mass="14454" checksum="112968D9EB9786D6" modified="2016-11-30" version="1">MSLGFELNRMAEEMIVIRAIPALLSGTDVALLVQDVLADIIEHGMSQRVEQSCNEILSTIACHGSVRANRRLTVPEMNVLLRDMEKTERSGQCNHGRPTWVELSKKSWISCFCVGSDELRKYYLIICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ96</accession>
    <name>A0A1D3RQ96_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BAZMOX_06712_3</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000943">
        <property type="protein sequence ID" value="SCN47719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="140"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="204"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SCN47719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="450" mass="48719" checksum="52D1B81A78D2823E" modified="2016-11-30" version="1">MQVNRPQDHSDIHLEQIMKDLDEGALYDARNHLLSLYPAEIALLLRSLPTEYRYRLWSIVAPEVMGQILVALQGEVRIGLIEHTSVQDLVTGANELTPRDLADLVGDFSAEVRDRVLRKKKDSRLEAALAYDGHTAGGLMTLDFLTVRADVTIDAVLRLLRVQKKMTGNMDSLFVVDRENHYQGILPAATILTTDPLMVVSKVMDTSITAIPLNMPVSEVATIFEHRDILSAAVVDDEGILVGRITVDDVVDVIREEADHAILSSAGLDEEHDLFSPVIVSARRRAVWLGVNLFTAFLASWVIGLFEATIDEIVALAVLMPVVASMGGIAGSQTLTLVIRGLALHQISSANAMSFLFKELAVGALNGIVWSVVVALIAAAWFSDMPLGMMLGGAMIINLTCAAFAGVMIPLFLQKRGIDPALAGGVLLTTVTDVIGFMSFLGLATIFLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQB1</accession>
    <name>A0A1D3RQB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P) transhydrogenase alpha subunit</fullName>
            <ecNumber evidence="2">1.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_11819_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="1.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01001070">
        <property type="protein sequence ID" value="SCN47890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_C" evidence="1">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="85" mass="8936" checksum="6FCF68024460DB39" modified="2016-11-30" version="1">MDTLTPFFIDIITGQITAAGKVPPAKVFIIGGGVAGLAAVGTARNMGAIVRAYDVRPAVKEQVESLGGEFLEVSVEVWLIDHNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC0</accession>
    <name>A0A1D3RQC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_101485_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01001033">
        <property type="protein sequence ID" value="SCN47846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008920273" evidence="1">
        <location>
            <begin position="22"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="409" mass="46728" checksum="071DC8C47535A4B1" modified="2016-11-30" version="1">MKNRLAIIGFLMCISSTQGYANDNSWIQNIRDQIDITEQAKSDNIDVENTYRLWPTAVKDAQFAKASYYSALNRVAQAQDRIKGRLIFHDLDQATVLYSNKALIGVWRCKNKAWTEMNITKNEATMLRTPAQELVRVNRRISGVNTAISCFVDLQNALWERFKIKWHFNNYPGSVDDDLMVFAELLRLRRKDHPSAITSLNHVTNFIKNIEKYIPDIVYDVWEGWNNNDSMGYRYTAACDDNKIKKVFIVMDGISGLSHWSGVNDLSSGDMAWPLQREVDDCGMVMLPLSIRYVNDGGVVSREWGFDLSPGSQSTVNMVKSIIDTIGLGVKVYLMKGTDYGHTAELVLDSLKKDDNVNHIAGLITIDKDTEISTIIVNRYFGDKLYSQCIAEELREDLIYYDLKRIIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQC2</accession>
    <name>A0A1D3RQC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_00666_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000962">
        <property type="protein sequence ID" value="SCN47749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="465" mass="54199" checksum="81789AEE055ED1FF" modified="2016-11-30" version="1">MWMRLNRIIVFLMVVIWNTPAFSVESNPVVQYQKLYQKSPMGVYSQGEWLLVVAEVPMNSDKQPKIYYEAKAMLQTQQLLKQFVLLQADLSGLKLHGFNGRLALDFDELVASGDFYHFSINNISVRLLDNKAYKSQYRRVTALKESALSSARLELFKTLNNSFIIQKLLSHARNNNALLARYYFDLGLLREAYFYKWQQLKSTYYLVNYPILDKTPFQRRQYLRRIFTTDSKDYQLDWLKQLPANAELFAQIQADIGNMDRLGQGLLDWLLAATLPMQDYEQQLDKVIQRLEPLAPNAQVKAEFVFLKKNRISKLVLDTYPSILQDILNQQGFLILDTKYSDENTAYFEQAVSLFNQGRKVDKVLTLLIQSLVESPRHIKSWVYLGAVLKYKKHYIESLAAFQQASLLNHSDPDNQANIAEIYFELKQPELAEAYLYYLQQQPVKNLSAYTKKVMSHLVNIKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQD8</accession>
    <name>A0A1D3RQD8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Malyl-CoA lyase</fullName>
            <ecNumber evidence="6">4.1.3.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_18662_0</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="4.1.3.24" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01001051">
        <property type="protein sequence ID" value="SCN47874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043959">
        <property type="term" value="F:L-erythro-3-methylmalyl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050083">
        <property type="term" value="F:malyl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="5">
        <location>
            <begin position="19"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="316" mass="34031" checksum="87914C9417090E46" modified="2016-11-30" version="1">MSHTLYEANAQRVHRCELAVPGSSPEMFEKALKSGVDVIFLDLEDAVAPDDKLQARKNVIKAINELDWAGHGITVSIRINGLDTQYMVRDVVDLVEQCGDKIDTILIPKVGVYSDVYMVEAMLNQLEMQQGMTKKIGIECLIETALGMANVEDIAKQGALGGRLEALHFGVADYAASNRARTTNIGGLNPDYPGDQWHFAISRMTVACRAYGLRAIDGPFGDIKDPEGFKDAARRAAALGCEGKWAIHPSQIALANEVFTPPVTEVEKAKRILQALKEAAAQGKGAAALDGRLIDAASEKMANNVVKTAEAIAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE1</accession>
    <name>A0A1D3RQE1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_17185_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001088">
        <property type="protein sequence ID" value="SCN47920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38039">
        <property type="entry name" value="PTHR38039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="84" mass="10012" checksum="145DF8E4B6C53CAA" modified="2016-11-30" version="1">MNLSFAPKAWDSYLYWQKTDKATVKRINTLIKEIQRSPFEGIGKLEPLKHALSGFWSRRINDEHRIVYKVTDNTIMMAQLRYHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQE2</accession>
    <name>A0A1D3RQE2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BAZMOX_33220_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001084">
        <property type="protein sequence ID" value="SCN47911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="350" mass="39591" checksum="BD8BAD2F4896B3A8" modified="2016-11-30" version="1">MPENQYIDALLADLAQDIAQFSETRPIQSIFMGGGTPSLFSAQHIQHLLEGVQKQLDFADDIEITLEANPGTFESEKFTDYRAIGINRLSIGIQSFHEQHLKRLGRIHSAQEAIRAVTIAQQAGFENLNLDLMFGLPESSEQDSINDVRQAITLQPSHISFYQLTLEPNTYFHKYPPVLPEDDAIFNSQLACQELLAQHGYLQYEISAYAQADKQCSHNLNYWSFGDYLGIGAGAHGKITQNTPHNIVRTTKPKQPEQYLKQDKSKRFAHAINSNDLALEFVMNNLRLKGGFSLDIYTQRTGLSAQTLEPALTHCLNQGLLVQHQQQYYCSEKGWHFLDSILEKFLGSWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQJ3</accession>
    <name>A0A1D3RQJ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplA</name>
        <name evidence="10" type="ORF">BAZMOX_30461_2</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001018">
        <property type="protein sequence ID" value="SCN47829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="231" mass="24363" checksum="E2587A7B414FB77A" modified="2016-11-30" version="1">MTKLSKRAKIAIEKVDPTRQYPFAEAIKLLKELSTVKFSESVDLSVNLGIDARKSDQNVRGATVLPKGSGKTVRVAVFTQGPNAEAAKEAGADIVGMEDLADLVKKGQMDFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPDVAGAVRNAKSGQARYRTDKAGIIHCSVGKIDFTAEDIKTNLEAVVADLVKAKPSAAKGIYLKKISLSTTMGPGVTLDLSSIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQL2</accession>
    <name>A0A1D3RQL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydrofolate synthase / Folylpolyglutamate synthase</fullName>
            <ecNumber evidence="5">6.3.2.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_01607_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.12" evidence="5"/>
    <dbReference type="EMBL" id="FMJP01001034">
        <property type="protein sequence ID" value="SCN47849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="4">
        <location>
            <begin position="47"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="428" mass="46656" checksum="728D78EA65A761BB" modified="2016-11-30" version="1">MHFDTLKGWLDWQESLHPKSIDLGLDRVTEVYSRLNPSGIEPITITVAGTNGKGSSIAFLEAIYRAQGLRVGSYTSPHILKYNERIKIDGTPVSDALLCSAFERIEAVRNNVSLSYFEFSTLAALDIFSRANLNIQLLEVGLGGRLDAVNIIDSDAAIITSIGIDHTAWLGNTRDAIAVEKAGVFRNNTPAIIGDPTPPQSLLDCAINIDAKLLRIGHEFSYSKVDNSWSWQSGNSTLNNLPLPKLKGTHQYRNAAAVITAVQALQNRIPVSKLAIQQGLGSANLLGRFQLINTSPAVLLDVSHNPQAAQTLVEYLQSEFKNTPVHAVFTMMGDKDLPGVIDLVQPCIKHWYISPLDNPRTSTDTDLKKAFASCHNTQVSYGFTDFRAAFNAAKTQAQADNGLILVFGAFFLVSECLSCLNAQQGESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQP8</accession>
    <name>A0A1D3RQP8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="4 8">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_28938_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="4 8"/>
    <dbReference type="EMBL" id="FMJP01001025">
        <property type="protein sequence ID" value="SCN47838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="9">
        <location>
            <begin position="178"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="128"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="32"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="74"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="481" mass="52106" checksum="4C035A1D6099DDB0" modified="2016-11-30" version="1">MKADIGLIGLAVMGQNLVLNMNDHDFKVAAHNRSANKIDDFLAGPAAGTQVTGAYSLVELVDSLKSPRIVMLMVKAGEVVDSYIEQLTPLLAPGDIIIDGGNSLYTDTNRRSIALAEKGIEFVGAGVSGGEEGARHGPSIMPGCSKDAWQIVQPILQSIAAKVDGEPCCQWVGEQGSGHYVKMVHNGIEYGDMQIICEAYQLLSEGLGLSADEIQNIFAQWNKGVLNSYLIEITTNILGYKDEDGEPLVNKILDTAGQKGTGKWTGINALDLGAPLTLIAEAVFARCLSAQKEERVRAANILPQANVKFSGDKETAIKAIGDAVYAAKIISYAQGFGLMRAAEKEYGWQLNYGGIALMWRGGCIIRSQFLNDIKEAYDNNPELENLLLADFFNNAIKESDAGWRETVVLGVQLAVPTPSFSSALAYYDGYRSARLPANLLQAQRDYFGVHTYERIDKPRGEFFHTDWTGTGGKMASTTYTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQV2</accession>
    <name>A0A1D3RQV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type I restriction-modification system, DNA-methyltransferase subunit M</fullName>
            <ecNumber evidence="1">2.1.1.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_02029_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="2.1.1.72" evidence="1"/>
    <dbReference type="EMBL" id="FMJP01001039">
        <property type="protein sequence ID" value="SCN47857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="68" mass="7730" checksum="EC381D768FB17755" modified="2016-11-30" version="1">MANNQAIDAFMGKYITKPFELLENVVGVEINFNKIFYKPEKLRSVGDILEDIEKLDGQIKTLEAELAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLB7</accession>
    <name>A0A1D3RLB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-dihydrouridine(20/20a) synthase</fullName>
            <ecNumber evidence="6">1.3.1.91</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DusA-like U20-specific dihydrouridine synthase</fullName>
            <shortName evidence="6">U20-specific Dus</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_15316_3</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NAD(+) = H(+) + NADH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53340"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NADP(+) = H(+) + NADPH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53336"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NAD(+) = H(+) + NADH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53348"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NADP(+) = H(+) + NADPH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53344"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Dus family. DusA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.91" evidence="6"/>
    <dbReference type="EMBL" id="FMJP01000053">
        <property type="protein sequence ID" value="SCN46456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102264">
        <property type="term" value="F:tRNA-dihydrouridine20 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02041">
        <property type="entry name" value="DusA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004653">
        <property type="entry name" value="DusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907">
        <property type="entry name" value="PTHR42907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00742">
        <property type="entry name" value="yjbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="9">
        <location>
            <begin position="19"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 8">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="21"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="215"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN46456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="332" mass="36969" checksum="C4A931F5D4278A50" modified="2016-11-30" version="1">MLQSKSSNTKDVPCRAVCIAPMLDWSDRHCRYFHRLLSKHIVLYTEMVTTGALINGDVQRHLDYSPQEHPLALQLGGSSVHDLALCSKMAEDYGYDEVNLNVGCPSDRVQNGRFGACLMAEPELVAECVAAMQQVVNIPVTVKTRIGIDDKDSYAELVNFISKVADGGCGTFILHARKAWLSGLSPKQNRDIPPLRYDIVQQIKQDFPRLEIIINGGINSLEQSALLMQGVDGVMIGREAYHNPYLLAQVDKLVYQQNTLVKTREEVVFALLPYIQEQLAAEVRLHSITRHILGLFHSVQGARAWRRHLSTFGPKAGADENVVLQALELVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLI8</accession>
    <name>A0A1D3RLI8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_105338_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000108">
        <property type="protein sequence ID" value="SCN46530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="57" mass="6348" checksum="E95EBD999AC9BF4F" modified="2016-11-30" version="1">MCTMELVDFSKTISLPLYGLKDGGYKYIVNDKFSGVFNISDSVVETPQPDDNDVLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RLZ6</accession>
    <name>A0A1D3RLZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Probable low-affinity inorganic phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BAZMOX_04516_0</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000219">
        <property type="protein sequence ID" value="SCN46692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SCN46692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="185" mass="20473" checksum="6DF7C43E3B77D6AC" modified="2016-11-30" version="1">MLIGALGLSLGLALYGAKLIKTVGTEITELDKMRAFCVSMAAAITVIIASQLGLPVSSTHIAVGAIFGVGFLREYLKRTNAKRLEEIRAHHETLDPEKTEAFLEDFRKASVAKKSTLLAELKKQAKKSQTDFTKRERKALKKVYQEQLVKRSHVYKIAAAWIITVPLSALLAAMLYFTIRGIMLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RM97</accession>
    <name>A0A1D3RM97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_178809_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000158">
        <property type="protein sequence ID" value="SCN46587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="95" mass="10893" checksum="642D974973A0E55B" modified="2016-11-30" version="1">MIDNPKPNLETVRNIVEQIAKGLRAFHRLEMLHQDLRPENIMIDSTGTVKIIRRAILPHEILGTPVTKYSLTYGANWISPSTPCVRFNFAQKPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMC4</accession>
    <name>A0A1D3RMC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_129637_1</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000230">
        <property type="protein sequence ID" value="SCN46709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN46709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="54" mass="6226" checksum="E9C54E04530C58DE" modified="2016-11-30" version="1">MEEIEDCRKKKSTYAIAELLTACLAMFLFKAESRNGLNNLREDLRFEKNLSASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-12-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RMK5</accession>
    <name>A0A1D3RMK5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DctM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_03539_2</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FMJP01000250">
        <property type="protein sequence ID" value="SCN46738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006066">
        <property type="entry name" value="HI0050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="399"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="11"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN46738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="458" mass="49283" checksum="C45E885C9CFA59CE" modified="2016-11-30" version="1">MDSYMALWMFFAVFVVLLSGYPVAFVLSGTALLFALLGLQMDTFDADFLAALPNRLFGIMNNETLIAVPLFVFMGVMLERAKIAESLLEAMSELFGSLHGGLGLAVTIVGMLMAASTGIVGATVVTMGLLSLPTMLKRGYDPSISCGIICASGTLGQIIPPSIVLVLLGDVISTAYQQAQLDMGVFAPETISVGDLFAGALVPGLLLVFMYLIYIVVTAWLRPDALPKPEKTRNHEQGFYFRVFKSLLPPLLLILAVLGSIIGGLATPTEAASVGAIGAIFLAFVSGQLNKEILQDVTRNTTRITSMVFMILIGAALFSLVFRGFEGDEIIIELLSDLPGGKFGALFIVMLVMFLLGFVLDFIEITFVIVPIVGPVLLAMGLDPVWLGIMIALNLQTSFLTPPFGFALFYLRGVAPEEVTTGQIYKGVFPFILIQLFLLGVLAYFPELATWLPSLIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN40</accession>
    <name>A0A1D3RN40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase associated protein RapA</fullName>
            <ecNumber evidence="2">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_00434_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EC" id="3.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="FMJP01000482">
        <property type="protein sequence ID" value="SCN47064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040765">
        <property type="entry name" value="Tudor_1_RapA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18339">
        <property type="entry name" value="Tudor_1_RapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor_1_RapA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="65" mass="7292" checksum="D47D739631CC2975" modified="2016-11-30" version="1">MVGQRWVSASEPELGLGMVLAVEANRVTVLFLASNERRVYAQNNSPLTRVRFCLMIKLRSKAVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN48</accession>
    <name>A0A1D3RN48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_159650_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000424">
        <property type="protein sequence ID" value="SCN46979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN46979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="140" mass="16595" checksum="65BEEC205F8915A2" modified="2016-11-30" version="1">MLKSAGILISFFLYQNEIDVCFQVRLQGYEIFYDPDFVVIHRGSPSQRPGWRRVFFPTRNTLWLIRRYYPQPLAIYMLGSRIIIGLVRAISFHEVRHYCRALKAGLCTPIQKTILPYPLQQQGKSFFRQNSLFHQLLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RN76</accession>
    <name>A0A1D3RN76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_82608_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000562">
        <property type="protein sequence ID" value="SCN47165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="44" mass="5056" checksum="607FC16F580EC2AC" modified="2016-11-30" version="1">MSKRTSNSRALREEIDFGINTNGLPVIVVYPDYSEESDIIKLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNB4</accession>
    <name>A0A1D3RNB4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BAZMOX_00840_6</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000567">
        <property type="protein sequence ID" value="SCN47181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="28"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="129"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="SCN47181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="240" mass="27149" checksum="153D13195F677AC5" modified="2016-11-30" version="1">MEKQQIGKHISHKFNEEIEDIRNQFLIMGGLVEQQLADAVEALVTGNLELAEKVIQSDTDVNNLEHDIDESCLLIIAKRQPAAFDLRLLIAISKAITELERVGDQAKRIADMAIKLEEFNKGYTDFHELKHLLELVRSILNDALDSFARLDVGSAVEVVLRDKDVDEEYISIFRQLTLSMMEDSRNIKRTLNIMNAIRSLERISDHAGNVCDYVIYAVQGQDVRHIPDDKVKAAVLGHST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNC9</accession>
    <name>A0A1D3RNC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_291663_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000549">
        <property type="protein sequence ID" value="SCN47146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="78" mass="8385" checksum="DC6369A68942A82D" modified="2016-11-30" version="1">MTAADLTGADLTWGRFDWKSVEHGGLNDAIKHSVTESTELNPGCQQPFLFDKMSSAGKTPAAKKSAAKKAVKSPKEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNJ1</accession>
    <name>A0A1D3RNJ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="9">5.3.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmhA</name>
        <name evidence="11" type="ORF">BAZMOX_03110_0</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SIS family. GmhA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="9"/>
    <dbReference type="EMBL" id="FMJP01000634">
        <property type="protein sequence ID" value="SCN47285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00041">
        <property type="reaction ID" value="UER00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008968">
        <property type="term" value="F:D-sedoheptulose 7-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001061">
        <property type="term" value="P:D-glycero-D-manno-heptose 7-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00067">
        <property type="entry name" value="GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004515">
        <property type="entry name" value="Phosphoheptose_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="35"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="50"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="92"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SCN47285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="189" mass="20446" checksum="7A7E11F14C186FBB" modified="2016-11-30" version="1">MTTHKSFSDVIQEHQQVTNQLTSCTPLITAASKLIISSLTSGHKLLLCGNGGSAADCQHFAAELVIRYHKNRRAYPAIALTTDSSILTAHANDFAFDSLFSRQVEALGNAGDCLIAISTSGNSENIIQAAITAKQQNMTVIGLIGGDGGRLKERVDMPIVIPSHTTARIQEAHMLIYHWWCEKVDEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN1</accession>
    <name>A0A1D3RNN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sigma-54 dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BAZMOX_01495_4</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000666">
        <property type="protein sequence ID" value="SCN47325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SCN47325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="163" mass="18972" checksum="AC93EB213FA0E8CC" modified="2016-11-30" version="1">MAQELFRKDLYYRINVVQLEIPPLNERPEDLPALIDLILQRMSKKHNKSVTSVSSSVMQKVLAYHWPGNVRELENTLERSLLFTTGKEITELKLDTVESSSKIINWKQKKEQAIAEVEQAFLQVSLQQYQGDIQKIASCMEISTRAVYNKLKKYKINPADYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RNN3</accession>
    <name>A0A1D3RNN3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xerD</name>
        <name evidence="15" type="ORF">BAZMOX_53790_0</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01000613">
        <property type="protein sequence ID" value="SCN47246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01807">
        <property type="entry name" value="Recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011932">
        <property type="entry name" value="Recomb_XerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02225">
        <property type="entry name" value="recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="104"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SCN47246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="293" mass="33142" checksum="649707AF90AABCC9" modified="2016-11-30" version="1">MSSKQLIDTFIDALWVENGLSKNTLSAYASDLRIFHKSLNKPIEQASNSDICLFLSQRYEQGISARSSARILSSLRRFYTYLLREKQVITDPTALIDQPQLGRPLPDSLSEHDIDLLLEAPEPSSILGARDKAMLEMLYATGLRVSELVNLSNDEINLRMGVLRVTGKGNKERLVPIGEQALSCLEEYMQHSRKTLLSERQCNTIFVTNRGAGMTRQAFWHIIKRYAKKAGITKELSPHTLRHAFATHLLNHGADLRVVQLLLGHSDLSTTQIYTHVANERLKELHSLYHPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RP36</accession>
    <name>A0A1D3RP36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_04655_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000620">
        <property type="protein sequence ID" value="SCN47258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="38" mass="4279" checksum="8500A8105A916AD8" modified="2016-11-30" version="1">MQANVGGIDKTIRIIAVGAYFQSWSGGCRYHPSYNRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPE3</accession>
    <name>A0A1D3RPE3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_148500_0</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000830">
        <property type="protein sequence ID" value="SCN47563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="57"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="285" mass="32793" checksum="3EB4F93E3B5649DD" modified="2016-11-30" version="1">MKKHFEKDYNRLVKEKLSATDKKNAMEQSIGGHFHLFGIFQRELLLQQGLKKNDVILDIGCGSGRLANALKAMPDIKFIGIDVVQELLDYANEICQRDDWSFIKVTDLKIPLADNSADIITSFSVFTHLLHEETYVYLAEMRRVLKPGGKIVFSFIDFSVPEHWIFFPSNLIQLNDRVPLNQFIDHQAIKIWCQHLQLGIENIFPGNQPYIQLNEPVEDENGGIYQGKVTLGQSVCVIQKPKYEILPDDFNPQKYLELNPDVAEAKIDPKVHFIVYGQLENRKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPN9</accession>
    <name>A0A1D3RPN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Chorismate synthase</fullName>
            <ecNumber evidence="4 8">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BAZMOX_04184_0</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the chorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8"/>
    <dbReference type="EMBL" id="FMJP01000731">
        <property type="protein sequence ID" value="SCN47407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SCN47407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="265" mass="28868" checksum="C1341409A087A55A" modified="2016-11-30" version="1">MSGNSIGKLFTVTTFGESHGIALGATIDGCPPGLELTEADLQGDLDRRRPGTSRHTTQRREADQVEILSGVFEGKTTGTPIGLLIKNTDQRSKDYANIAETYRPGHADYVYDHKYGFRDYRGGGRSSARETAMRVAAGGIAKKYLKQQYGIEIRGYLSQLGPIKIEAIDWVAMDKSEFFCPDASKEAELVAYMDALRKEGDSIGAKVNVMATNVPPGLGEPIFDRLDADLAHALMSINAVKGVEIGDGFDCVNVKVRVFRDEIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2020-04-22" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPP1</accession>
    <name>A0A1D3RPP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BAZMOX_160466_0</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000909">
        <property type="protein sequence ID" value="SCN47663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="SCN47663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="119" mass="13549" checksum="0C69B16752BEC672" modified="2016-11-30" version="1">MIRERKSYSLAMAQIEKDFTQAINKHFSQSFQEGQKVLVSFVQFDGMRDVDELKACIESLPLTKSVAVGSIENRGVVYEVIYLGNPNDLQLNIMKKSREFRLRGLRAKSNNGGIIAFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPQ5</accession>
    <name>A0A1D3RPQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphate starvation-inducible ATPase PhoH with RNA binding motif</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_26533_1</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000801">
        <property type="protein sequence ID" value="SCN47519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="3">
        <location>
            <begin position="110"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="320" mass="35715" checksum="67729C49AEB350B5" modified="2016-11-30" version="1">MSTETLELILEPADNQRLANLCGEFNGNLQQIEQRLQVEIANRGNQFNVSGTAEAVKGTGAVLNKLFIEAEHEEITPEHIHLSMQDAHIEDIGQDDNLSEVFIKTKRGVLKGRGANQKDYLRRILNHDINFGVGPAGTGKTYLAVACAVEALQSEQVRRIVLVRPAVEAGEKLGFLPGDMAQKVDPYLRPLYDALYEMLGFERAEKLIERKIIEVAPLAFMRGRTLNDSFIILDEAQNTTTEQIKMFLTRVGFGSTAVITGDITQIDLPNEKMSGLKHVLKVLDKVEGISFTFFGAKDIVRHPLVQRIVVAYENYERAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RPZ4</accession>
    <name>A0A1D3RPZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BAZMOX_49357_2</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000831">
        <property type="protein sequence ID" value="SCN47568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="3">
        <location>
            <begin position="13"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="SCN47568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="343" mass="37434" checksum="BF987B3E9D4ABEC7" modified="2016-11-30" version="1">MTDKYKIIEHEYDVVVVGAGGAGLRATFGMAEKGLKTACISKVFPTRSHTVAAQGGISAALGNNGEDDWRWHMYDTVKGSDWLGDQDAIEYMCREAIPAVLELEHYGVPFSRNPDGKIYQRAFGGMTTHFGEGTAQRTCAAADVTGHAILHTLYQQALKHEAEFFIEYVVLDLIMEEGVCRGVLAWCLDDGALHVFKAHTVVLATGGYGRCYFSCTSAHTVTGDGSAMVLRAGLPLQDMEFIQFHPTGIYGAGCLITEGVRGEGGYLTNSEGERFMERYAPHAKDLASRDVVSRAITMEVIAGRGVGENKDCAFLHLEHLDPELIHERLPGISETARILLVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ00</accession>
    <name>A0A1D3RQ00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conjugative transfer protein TrbE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BAZMOX_02191_4</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000875">
        <property type="protein sequence ID" value="SCN47619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P-loop_TraG" evidence="1">
        <location>
            <begin position="168"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="SCN47619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="351" mass="39929" checksum="A231D67614F17621" modified="2016-11-30" version="1">MLGILAMQWLRYPKAQVVFFDKDRTARAATMAVGGSIYEPGNEDRPVAFQPLVNIDQKSDLNWAEGWIETLMDLQNLTLTPKDKTEIHNALQSLATSPRKQRTIGGLQQLIQNQDIRDALMQYTLEGTYGQLFDSDNDTLQDDFWTMIEMGSLMDLGNSAIVPALGYLFYRIEQRFDGRPTLLILDEAWLFMDHPFFATRLRQWLKTLRKKNVFVVFATQEIEDAINSPICSTLLSACMTKIFLPDNSATDPLTSEAYTKLGLSETEIINLSRAVQKKEYFYRSPKGKRLFDLELGDVALAFVGRSSPSDQAFMDDLEKNHSSEQWAELLLRQRNLTWAADMVSEPLSVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQ22</accession>
    <name>A0A1D3RQ22_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase_S8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BAZMOX_72554_1</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="FMJP01000998">
        <property type="protein sequence ID" value="SCN47791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="4">
        <location>
            <begin position="3"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="SCN47791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="150" mass="16168" checksum="24A60346030244CC" modified="2016-11-30" version="1">MPNFKGTSAAAPNAAAVAALLLQKYSYLKPTQVKQVMMHGTIDLIDPANVQNEVQLATNPCAQGVQFDWGTGCGLIQLDLMFEAANHLFLTGLGDLNKDGCVNSRDSAILVAVLRSSTEMQRLYDLTGDGKITDRDFNALLALYDGECTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1D3RQG0</accession>
    <name>A0A1D3RQG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA repair protein RadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BAZMOX_02007_1</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">methanotrophic endosymbiont of Bathymodiolus azoricus (Menez Gwen)</name>
        <dbReference type="NCBI Taxonomy" id="343232"/>
        <lineage>
            <taxon>Bacteria</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Petersen Jillian"/>
                <person name="Sayavedra Lizbeth"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <dbReference type="EMBL" id="FMJP01001073">
        <property type="protein sequence ID" value="SCN47894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000198961">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="102"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SCN47894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000198961"/>
        </source>
    </evidence>
    <sequence length="224" mass="25093" checksum="D9D560D6C9688B7A" modified="2016-11-30" version="1">MSIQDWPEGDRPREKLLAQGAEILSDAELLAIFLRTGIKGKTAVDLARDLLTDFGSLRELLLADCDNFTRAKGLGTAKYAQLQAVLEMARRHTFEELDRGDILTSPEATRAYLSQQLRHYQYEVFACLFLDNQHHILEFEELFRGTIDSASVYPREVIKKALAHNAAAVIFAHNHPSGISEPSQADKLITDKLKQALALIDIRVLDHFIIGDGMPYSFAENGLL</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>